N. Klopp

P. Rzehak, N. Klopp, T. Illig, 2013, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques – Tampere Vascular Study

T. Lehtimäki, N. Klopp, T. Illig, 2017, Scientific Reports.

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds.

T. Lehtimäki, N. Klopp, T. Illig, 2015, Atherosclerosis.

DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a case-control study

H. Brenner, N. Klopp, T. Illig, 2011, BMC Cancer.

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk

H. Brenner, J. Chang-Claude, M. Hoffmeister, 2010, International journal of cancer.

Polycyclic aromatic hydrocarbons from diesel emissions exert proallergic effects in birch pollen allergic individuals through enhanced mediator release from basophils

N. Klopp, H. Behrendt, J. Buters, 2009, Environmental toxicology.

An association between a variation in the PSCA gene and upper gastrointestinal cancer in Caucasians

N. Klopp, T. Illig, W. Chow, 2011 .

Association study between the D10S1423 microsatellite marker and Alzheimer's disease

H. Gohlke, N. Klopp, T. Illig, 2006, Neurobiology of Aging.

Expression and regulation of interferon-related development regulator-1 in cystic fibrosis neutrophils.

N. Klopp, T. Illig, S. Zielen, 2013, American journal of respiratory cell and molecular biology.

Somatic Mutations and Inborn Variants in Exon 12 of ASXL1 in Different Myeloid Neoplasms

H. Wichmann, N. Klopp, T. Illig, 2011 .

Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms

Bernhard Horsthemke, Bernward Klocke, Melina Claussnitzer, 2014, Cell.

New loci associated with kidney function and chronic kidney disease

Uwe Völker, Luigi Ferrucci, Reinhold Schmidt, 2010, Nature Genetics.

Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life

H. Wichmann, N. Klopp, T. Illig, 2009, Allergy.

Analysis of the individual and aggregate genetic contributions of previously identified SPINK 5 , KLK 7 and FLG polymorphisms to eczema risk

C. Strobl, N. Klopp, T. Illig, 2015 .

Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study).

C. Gieger, W. Rathmann, C. Meisinger, 2007, European journal of endocrinology.

A MULTICOPY c‐myc TRANSGENE AS A NUCLEAR LABEL: OVERGROWTH OF Myctg50CELLS IN ALLOPHENIC MICE

N. Klopp, M. Augustin, H. Jockusch, 1998, Cell biology international.

IL6 Gene Promoter Polymorphisms and Type 2 Diabetes

C. Gieger, W. Rathmann, T. Hansen, 2006, Diabetes.

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Christian Gieger, Inês Barroso, Meena Kumari, 2011, Nature Genetics.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2012, Nature Genetics.

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS

Christian Gieger, Nicholas J Timpson, Manuel A. R. Ferreira, 2011, Nature Genetics.

A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease

Olli Saarela, Frank Kee, Kaisa Silander, 2011, Circulation. Cardiovascular genetics.

Genetic variants in the GATA3 gene are not associated with asthma and atopic diseases in German children.

N. Klopp, T. Illig, J. Adamski, 2009, The Journal of allergy and clinical immunology.

[Centralized biobanks: a basis for medical research].

N. Klopp, T. Illig, M. Hummel, 2016, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis.

N. Klopp, T. Illig, S. Weidinger, 2007, The Journal of investigative dermatology.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Nick C Fox, Michelle K. Lupton, Charles C. White, 2019, Nature Genetics.

Discovery and Refinement Supplementary

Christian Gieger, Cisca Wijmenga, Inês Barroso, 2015 .

Original article: Polymorphisms in eosinophil pathway genes, asthma and atopy

S. Weiland, B. Niggemann, N. Klopp, 2007, Allergy.

Edinburgh Research Explorer Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Daniel L. Koller, C. Gieger, A. Morris, 2018 .

Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk.

N. Klopp, T. Illig, E. von Mutius, 2010, The Journal of allergy and clinical immunology.

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

J. Chang-Claude, H. Dienemann, H. Wichmann, 2008, BMC Cancer.

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators.

C. Gieger, A. Peters, E. Boerwinkle, 2010, Blood.

Quality Assessment of the Preanalytical Workflow in Liquid Biobanking: Taurine as a Serum-Specific Quality Indicator for Preanalytical Process Variations.

N. Klopp, T. Illig, F. Betsou, 2019, Biopreservation and biobanking.

Influence of FADS Polymorphisms on Tracking of Serum Glycerophospholipid Fatty Acid Concentrations and Percentage Composition in Children

P. Rzehak, N. Klopp, J. Heinrich, 2011, PloS one.

Lack of association between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema.

N. Klopp, T. Illig, J. Ring, 2006, The Journal of allergy and clinical immunology.

Dissection of Genetic Factors Modulating Fetal Growth in Cattle Indicates a Substantial Role of the Non-SMC Condensin I Complex, Subunit G (NCAPG) Gene

N. Klopp, K. Flisikowski, R. Fries, 2009, Genetics.

Dissection of genetic factors modulating fetal growth in cattle indicates a role of the non-SMC condensin I complex, subunit G ( NCAPG ) gene

N. Klopp, K. Flisikowski, R. Pfuhl, 2009 .

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease.

Marc N. Offman, A. Peters, B. Rost, 2011, American journal of human genetics.

SARS-CoV-2 seroprevalence in Germany - a population based sequential study in five regions

N. Klopp, T. Illig, T. Tonn, 2021, medRxiv.

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

W. Rathmann, A. Hofman, A. Uitterlinden, 2011, Nature Genetics.

Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus

L. Liang, C. Gieger, T. Meitinger, 2008, PLoS genetics.

Unifying Candidate Gene and GWAS Approaches in Asthma

Jon Genuneit, Ivo G. Gut, Erika von Mutius, 2010, PloS one.

Safety and immunogenicity of an mRNA-lipid nanoparticle vaccine candidate against SARS-CoV-2

N. Klopp, P. Kremsner, M. Fotin‐Mleczek, 2021, Wiener klinische Wochenschrift.

Refining Kidney Survival in 383 Genetically Characterized Patients With Nephronophthisis

N. Klopp, J. Gerss, H. Omran, 2022, Kidney international reports.

Wnt signaling and Dupuytren's disease.

Peter Nürnberg, Andre Franke, Cisca Wijmenga, 2011, The New England journal of medicine.

CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children

S. Weiland, N. Klopp, T. Illig, 2007, International Archives of Allergy and Immunology.

Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population

M. Akmatov, N. Klopp, T. Illig, 2017, Human vaccines & immunotherapeutics.

Genetic Association Study Identifies HSPB7 as a Risk Gene for Idiopathic Dilated Cardiomyopathy

I. König, L. Fauchier, V. Regitz-Zagrosek, 2010, PLoS genetics.

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

Simon C. Potter, Thomas W. Mühleisen, Benjamin J. Wright, 2011, PLoS genetics.

The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation

N. Klopp, T. Illig, J. Graw, 2009, Molecular vision.

TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants.

P. Rosenstiel, N. Klopp, T. Illig, 2009, The Journal of allergy and clinical immunology.

The effect of BDNF gene variants on asthma in German children

N. Klopp, T. Illig, L. Pinto, 2009, Allergy.

Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P

N. Klopp, T. Illig, B. Lorenz, 2006, Graefe's Archive for Clinical and Experimental Ophthalmology.

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

M. Waldenberger, T. Lehtimäki, O. Raitakari, 2015, Human Genetics.

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk

N. Klopp, T. Illig, E. von Mutius, 2009, Allergy.

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (vol 41, pg 1088, 2009)

Nick C Fox, Moskvina, D. Rujescu, 2013 .

Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC)

S. Ring, N. Klopp, B. Koletzko, 2012, British Journal of Nutrition.

Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array

Christian Gieger, Thomas Meitinger, Nilesh Samani, 2009, PloS one.

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

Christian Gieger, Thomas Meitinger, Nilesh Samani, 2009, Human molecular genetics.

Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients

Marcus M. Scheunemann, Lennart M. Reinke, J. Papenbrock, 2022, Scientific data.

Evaluation of a multiplex PCR screening approach to identify community-acquired bacterial co-infections in COVID-19: a multicenter prospective cohort study of the German competence network of community-acquired pneumonia (CAPNETZ)

N. Klopp, T. Welte, N. Suttorp, 2021, Infection.

Shift in bacterial etiology from the CAPNETZ cohort in patients with community-acquired pneumonia: data over more than a decade

N. Klopp, T. Welte, G. Barten, 2021, Infection.

Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse.

N. Klopp, P. Selby, J. Favor, 2004, Investigative ophthalmology & visual science.

Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene

N. Klopp, T. Illig, W. Engel, 2007, Molecular vision.

Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family.

N. Klopp, T. Illig, P. M. Gopinath, 2006, Molecular vision.

Metabolite profiling reveals new insights into the regulation of serum urate in humans

Fabian J Theis, C. Gieger, M. Waldenberger, 2013, Metabolomics.

Association of NOD1 polymorphisms with atopic eczema and related phenotypes.

N. Klopp, T. Illig, J. Heinrich, 2005, The Journal of allergy and clinical immunology.

NOD1 variation, immunoglobulin E and asthma.

W. Cookson, A. James, S. Weiland, 2005, Human molecular genetics.

Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.

H. Brenner, J. Chang-Claude, M. Hoffmeister, 2010, Carcinogenesis.

Edinburgh Research Explorer Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Andrew D. Johnson, Nicholette D. Palmer, 2022 .

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Fabian J Theis, Andrew D. Johnson, Lorna M. Lopez, 2012, Nature Genetics.

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Tom R. Gaunt, Tom S. Price, Joseph T. Glessner, 2011, American journal of human genetics.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Nick C Fox, Michelle K. Lupton, Charles C. White, 2019, Nature Genetics.

other inflammatory mediators circulating concentrations of monocyte chemoattractant protein-1 and Duffy antigen receptor for chemokines (Darc) polymorphism regulates

C. Gieger, E. Boerwinkle, E. Benjamin, 2014 .

Abstract 1808: Duffy Antigen Receptor for Chemokines (Darc) Polymorphism Regulates Circulating Concentrations of Monocyte Chemoattractant Protein-1 and Other Circulating Inflammatory Mediators

C. Gieger, A. Peters, E. Boerwinkle, 2009 .

Toll-like receptor heterodimer variants protect from childhood asthma.

S. Weiland, N. Klopp, T. Illig, 2008, The Journal of allergy and clinical immunology.

A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.

R. Martins, N. Klopp, T. Illig, 2006, Human molecular genetics.

Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM.

Hermann Brenner, Jenny Chang-Claude, Thomas Illig, 2010, Carcinogenesis.

Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis.

D. Postma, X. Estivill, G. Koppelman, 2010, The Journal of investigative dermatology.

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.

Thomas W. Mühleisen, Michelle K. Lupton, A. Singleton, 2012, Journal of Alzheimer's disease : JAD.

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study.

T. Lehtimäki, N. Klopp, T. Illig, 2011, Atherosclerosis.

Genome-wide association study identifies 48 common genetic variants associated with handedness

Cameron D. Palmer, David M. Evans, N. Eriksson, 2019, bioRxiv.

Disentangling the genetics of lean mass.

Daniel L. Koller, D. Kiel, C. Gieger, 2019, The American journal of clinical nutrition.

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Olli Simell, Mark I. McCarthy, Karen L. Mohlke, 2012, Nature Genetics.

Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals.

H. Brenner, E. El-Omar, N. Klopp, 2011, Gastroenterology.

Three murine cataract mutants (Cat2) are defective in different gamma-crystallin genes.

N. Klopp, A. Prescott, G. Vrensen, 1998, Genomics.

N-acetyltransferase 2 Phenotype, Occupation, and Bladder Cancer Risk: Results from the EPIC Cohort

J. Chang-Claude, F. Clavel-Chapelon, E. Riboli, 2013, Cancer Epidemiology, Biomarkers & Prevention.

Genome-Wide Association Study to Identify Common Variants Associated with Brachial Circumference: A Meta-Analysis of 14 Cohorts

Christian Gieger, Alexander Teumer, Erika Salvi, 2012, PloS one.

Ethylnitrosourea-induced mutation in mice leads to the expression of a novel protein in the eye and to dominant cataracts.

H. Fuchs, E. Wolf, R. Balling, 2001, Genetics.

Bmc Medical Genetics Association between Variations in the Tlr4 Gene and Incident Type 2 Diabetes Is Modified by the Ratio of Total Cholesterol to Hdl-cholesterol

C. Meisinger, N. Klopp, T. Illig, 2022 .

Children and Adolescents’ Behavioral Patterns in Response to Escalating COVID-19 Restriction Reveal Sex and Age Differences

N. Klopp, T. Illig, T. Pietschmann, 2021, Journal of Adolescent Health.

Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol

Nilesh J Samani, Barbara Thorand, Muredach P Reilly, 2011, Circulation. Cardiovascular genetics.

Predicting sudden cardiac death using common genetic risk variants for coronary artery disease.

M. Waldenberger, T. Lehtimäki, N. Klopp, 2015, European heart journal.

Gene-Gene Interaction between APOA5 and USF1: Two Candidate Genes for the Metabolic Syndrome

W. Rathmann, H. Wichmann, C. Meisinger, 2009, Obesity Facts.

Genetic variants in the USF1 gene are associated with low-density lipoprotein cholesterol levels and incident type 2 diabetes mellitus in women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

C. Meisinger, N. Klopp, T. Illig, 2008, European journal of endocrinology.

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm – The Tampere Vascular Study

T. Lehtimäki, N. Klopp, T. Illig, 2017, Scientific Reports.

Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts

A. Peters, V. Salomaa, N. Samani, 2012, PloS one.

Association of the interleukin-1 receptor antagonist gene with asthma.

Matthias Wjst, Michael Knapp, Thomas Illig, 2004, American journal of respiratory and critical care medicine.

No Association Between the Putative Functional ZDHHC8 Single Nucleotide Polymorphism rs175174 and Schizophrenia in Large European Samples

S. Cichon, M. Rietschel, M. Nöthen, 2005, Biological Psychiatry.

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts.

T. Lehtimäki, N. Klopp, T. Illig, 2011, Atherosclerosis.

Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling.

T. Lehtimäki, E. Halperin, J. Viikari, 2011, Atherosclerosis.

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.

M. Wjst, H. Gohlke, N. Klopp, 2002, Human molecular genetics.

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.

A. Peters, T. Lehtimäki, V. Salomaa, 2012, Heart rhythm.

A genome-wide association study identifies three loci associated with mean platelet volume.

Christian Gieger, Thomas Meitinger, Henry Völzke, 2009, American journal of human genetics.

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

H. Brenner, N. Klopp, T. Illig, 2012, European journal of cancer.

Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk.

C. Gieger, H. Völzke, H. Wichmann, 2011, American journal of human genetics.

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Jingyuan Fu, Thomas Meitinger, Jan A. Kors, 2010, Nature Genetics.

No evidence for an association between variants at the ??-amino-n-butyric acid type A receptor ??2 locus and schizophrenia

S. Cichon, M. Rietschel, M. Nöthen, 2007 .

The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations

S. Weiland, B. Niggemann, N. Klopp, 2006, Respiratory research.

G-Protein-coupled receptor polymorphisms are associated with asthma in a large German population.

S. Weiland, N. Klopp, T. Illig, 2005, American journal of respiratory and critical care medicine.

Association of CARD15 polymorphisms with atopy‐related traits in a population‐based cohort of Caucasian adults

N. Klopp, T. Illig, H. Wichmann, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Scott M. Williams, Andrew D. Johnson, J. Danesh, 2012, Blood.

Putative association of a TLR9 promoter polymorphism with atopic eczema

N. Klopp, T. Illig, J. Ring, 2007, Allergy.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2013, Nature Genetics.

Running title: Pfeiffer et al.; genome-wide DNA methylation and blood lipid levels

D. Melzer, L. Pilling, A. Singleton, 2015 .

Genome-wide DNA methylation analysis reveals several loci important for blood lipid levels

S. Bandinelli, D. Hernandez, D. Melzer, 2015 .

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

A. Heinzmann, N. Klopp, T. Illig, 2015, The Journal of allergy and clinical immunology.

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism—The Young Finns Study

M. Waldenberger, T. Lehtimäki, J. Viikari, 2016, Scientific Reports.

Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults

H. Wichmann, N. Klopp, T. Illig, 2004, Journal of Medical Genetics.

Genome-Wide Association Analysis of High-Density Lipoprotein Cholesterol in the Population-Based KORA Study Sheds New Light on Intergenic Regions

C. Gieger, F. Kronenberg, T. Meitinger, 2008, Circulation. Cardiovascular genetics.

Association of a MTNR1B gene variant with fasting glucose and HOMA-B in children and adolescents with high BMI-SDS.

N. Klopp, T. Illig, H. Grallert, 2011, European journal of endocrinology.

Association study of mast cell chymase polymorphisms with atopy

R. Holle, G. Fischer, N. Klopp, 2005, Allergy.

FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children

H. Wichmann, N. Klopp, J. Heinrich, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

Niku Oksala, Thomas Illig, Terho Lehtimäki, 2014, Scientific Reports.

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.

D. Balding, M. Alpers, H. Wichmann, 2012, Human molecular genetics.

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes.

S. Cichon, M. Rietschel, M. Nöthen, 2005, The American journal of psychiatry.

Investigation of the DAOA/G30 locus in panic disorder

S. Cichon, M. Rietschel, M. Nöthen, 2005, Molecular Psychiatry.

Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder

S. Cichon, M. Rietschel, T. Schulze, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms

M. Platzer, N. Klopp, T. Illig, 2010, Molecular vision.

RANTES/CCL5 gene polymorphisms, serum concentrations, and incident type 2 diabetes: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

C. Meisinger, N. Klopp, T. Illig, 2008, European journal of endocrinology.

Altered aggregation properties of mutant γ‐crystallins cause inherited cataract

C. Dobson, N. Klopp, C. MacPhee, 2002 .

Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk

N. Klopp, T. Illig, J. Ring, 2009, Allergy.

11 novel Mutations in the Factor VIII encoding Gene lead to severe or moderate Hemophilia A

N. Klopp, J. Oldenburg, R. Schwaab, 2003 .

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes

Pashupati P. Mishra, M. Waldenberger, T. Lehtimäki, 2019, Scientific Reports.

Filaggrin mutations, atopic eczema, hay fever, and asthma in children.

S. Weiland, N. Klopp, T. Illig, 2008, The Journal of allergy and clinical immunology.

Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

N. Klopp, T. Illig, J. Ring, 2006, The Journal of allergy and clinical immunology.

No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample.

S. Cichon, A. Georgi, M. Rietschel, 2006, Psychiatric genetics.

CXCR1 and CXCR2 haplotypes synergistically modulate cystic fibrosis lung disease

N. Klopp, T. Illig, A. Gaggar, 2011, European Respiratory Journal.

Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromosome 10 and Alzheimer’s disease

N. Klopp, T. Illig, A. Kurz, 2004, Neurobiology of Aging.

ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome

N. Schmitz, N. Klopp, T. Illig, 2013, Leukemia.

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3.

C. Gieger, R. Vasan, H. Völzke, 2011, Human molecular genetics.

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.

T. Lehtimäki, N. Klopp, T. Illig, 2013, Atherosclerosis.

MMP-9 gene variants increase the risk for non-atopic asthma in children

N. Klopp, T. Illig, L. Pinto, 2010, Respiratory research.

Genetic variation in CRTh2 influences development of allergic phenotypes

N. Klopp, T. Illig, E. von Mutius, 2009, Allergy.

Genetic Variations in Polyunsaturated Fatty Acid Metabolism – Implications for Child Health?

N. Klopp, J. Heinrich, B. Koletzko, 2012, Annals of Nutrition and Metabolism.

SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease

Thomas Illig, Luciano Xumerle, Joachim Heinrich, 2008, Lipids.

An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis.

C. Gieger, A. Kretschmer, H. Prokisch, 2014, The Journal of investigative dermatology.

FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies

H. Wichmann, N. Klopp, J. Heinrich, 2012, Allergy.

IRF-1 gene variations influence IgE regulation and atopy.

S. Weiland, P. Rosenstiel, N. Klopp, 2008, American journal of respiratory and critical care medicine.

Variants of the FADS1 FADS2 Gene Cluster, Blood Levels of Polyunsaturated Fatty Acids and Eczema in Children within the First 2 Years of Life

D. Postma, P. A. van den Brandt, P. Dagnelie, 2010, PloS one.

A novel GJA8 mutation causing a recessive triangular cataract

N. Klopp, T. Illig, J. Graw, 2008, Molecular vision.

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10 p 11 . 23

C. Gieger, A. Peters, C. Loley, 2010 .

Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome The cardiovascular risk in Young Finns Study

M. Waldenberger, T. Lehtimäki, J. Viikari, 2014, Molecular and Cellular Endocrinology.

A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels.

S. Weiland, N. Klopp, T. Illig, 2004, The Journal of allergy and clinical immunology.

Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

C. Meisinger, N. Klopp, T. Illig, 2008, Atherosclerosis.

RANTES/CCL5 and Risk for Coronary Events: Results from the MONICA/KORA Augsburg Case-Cohort, Athero-Express and CARDIoGRAM Studies

Michael H. Preuss, C. Meisinger, N. Klopp, 2011, PloS one.

Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany

N. Klopp, T. Illig, T. Tonn, 2022, Frontiers in Immunology.

The Hannover Unified Biobank (HUB) – Centralized Standardised Biobanking at Hannover Medical School

N. Klopp, T. Illig, U. Lehmann, 2021, Open Journal of Bioresources.

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

C. Gieger, P. Deloukas, C. Wijmenga, 2013, PLoS genetics.

The KORA Eye Study: a population-based study on eye diseases in Southern Germany (KORA F4).

R. Holle, W. Rathmann, A. Peters, 2011, Investigative ophthalmology & visual science.

American Journal of Epidemiology Practice of Epidemiology Estimating the Single Nucleotide Polymorphism Genotype Misclassification from Routine Double Measurements in a Large Epidemiologic Sample

F. Kronenberg, A. Peters, H. Wichmann, 2022 .

A common atopy‐associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding

A. Kretschmer, M. Waldenberger, A. Peters, 2014, Allergy.

Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence

N. Klopp, T. Illig, M. Seifert, 2021, Frontiers in Oncology.

Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination

M. Akmatov, N. Klopp, T. Illig, 2017, BMC Medical Research Methodology.

Undiagnosed Diabetes Mellitus in Community-Acquired Pneumonia: A Prospective Cohort Study

C. Kropf-Sanchen, N. Klopp, T. Illig, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Genome-wide meta-analysis of common variant differences between men and women

E. Demerath, Toshiko Tanaka, S. Bandinelli, 2012, Human molecular genetics.

Genome-wide association study identifies 48 common genetic variants associated with handedness

Cameron D. Palmer, David M. Evans, N. Eriksson, 2020, Nature Human Behaviour.

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin

S. Cichon, M. Rietschel, M. Nöthen, 2004, Nature Genetics.

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm – The Tampere Vascular Study

T. Lehtimäki, N. Klopp, T. Illig, 2017, Scientific Reports.

Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.

T. Lehtimäki, N. Klopp, T. Illig, 2017, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

No association of two functional polymorphisms in human ALOX15 with myocardial infarction.

F. Kronenberg, C. Meisinger, A. Peters, 2009, Atherosclerosis.

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract.

C. Dobson, N. Klopp, C. MacPhee, 2002, The EMBO journal.

Genetic variants in Protocadherin‐1, bronchial hyper‐responsiveness, and asthma subphenotypes in German children

A. Heinzmann, N. Klopp, T. Illig, 2012, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

PSEA: Phenotype Set Enrichment Analysis—A New Method for Analysis of Multiple Phenotypes

Christian Gieger, Thomas Meitinger, Karsten Suhre, 2012, Genetic epidemiology.

Genetic variation in the Toll-like receptor signaling pathway is associated with childhood asthma.

L. Liang, A. Heinzmann, N. Klopp, 2013, The Journal of allergy and clinical immunology.

Genetic association between obstructive bronchitis and enzymes of oxidative stress.

N. Klopp, T. Illig, J. Heinrich, 2012, Metabolism: clinical and experimental.

Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression

S. Cichon, M. Rietschel, M. Nöthen, 2005, Biological Psychiatry.

No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia.

S. Cichon, M. Rietschel, M. Nöthen, 2006, Psychiatric Genetics.

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes

Pashupati P. Mishra, M. Waldenberger, T. Lehtimäki, 2019, Scientific Reports.

Ethylnitrosourea-induced base pair substitution affects splicing of the mouse gammaE-crystallin encoding gene leading to the expression of a hybrid protein and to a cataract.

N. Klopp, J. Favor, J. Graw, 2002, Genetics.

Characterization of a 1-bp deletion in the gammaE-crystallin gene leading to a nuclear and zonular cataract in the mouse.

N. Klopp, J. Graw, J. Löster, 2001, Investigative ophthalmology & visual science.

Further Genetic Heterogeneity for Autosomal Dominant Human Sutural Cataracts

M. Wjst, N. Klopp, T. Illig, 2003, Ophthalmic Research.

AREGPKD - A European ARPKD Registry Study

N. Klopp, T. Illig, S. Testa, 2015 .

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Tanya M. Teslovich, Andrew D. Johnson, Kyle J. Gaulton, 2014 .

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss

N. Klopp, T. Illig, C. Holzapfel, 2013, Obesity.

Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events: AtheroRemo Consortium

T. Lehtimäki, T. Laitinen, J. Viikari, 2013, Circulation. Cardiovascular genetics.

Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.

N. Klopp, J. Favor, J. Graw, 1998, Developmental genetics.

A Genome-wide Association Study Identiﬁes Three Loci Associated with Mean Platelet Volume

C. Gieger, A. Peters, P. Deloukas, 2022 .

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Tanya M. Teslovich, Andrew D. Johnson, Simon C. Potter, 2012, Nature Genetics.

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Simon C. Potter, Nicholette D. Palmer, Joshua P. Lewis, 2012, PLoS ONE.

Genome-wide meta-analysis of common variant differences between men and women

E. Demerath, Toshiko Tanaka, S. Bandinelli, 2012 .

Common variants at ABCA 7 , MS 4 A 6 A / MS 4 A 4 E , EPHA 1 , CD 33 and CD 2 AP are associated with Alzheimer ’ s disease

Nick C Fox, John X. Morris, Thomas W. Mühleisen, 2011 .

Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function

Lorna M. Lopez, Sina A. Gharib, Bonnie R. Joubert, 2011, Nature Genetics.

Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Tanya M. Teslovich, Kyle J. Gaulton, Sara M. Willems, 2015, Nature Genetics.

Common variants associated with plasma triglycerides and risk for coronary artery disease

Tanya M. Teslovich, Ross M. Fraser, May E. Montasser, 2013, Nature Genetics.

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Schadt, Talin, Jian-an, 2011 .

Effects of Repeated Freeze and Thaw Cycles on the Genome-Wide DNA Methylation Profile of Isolated Genomic DNA.

N. Klopp, T. Illig, M. Seifert, 2023, Biopreservation and biobanking.

Large-scale association analysis identifies new risk loci for coronary artery disease

J. Danesh, R. Collins, D. Absher, 2012, Nature Genetics.

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Bjarni V. Halldórsson, D. Kiel, C. Gieger, 2011, Nature genetics.

Nutrition, sirtuins and renin-angiotensin system: Cross talk in metabolic regulation

C. Gieger, W. Rathmann, J. Pankow, 2015 .

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Nicholette D. Palmer, Y. J. Kim, 2016, Nature Communications.

Polymorphisms in the IRF‐4 gene, asthma and recurrent bronchitis in children

A. Heinzmann, N. Klopp, T. Illig, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (vol 42, pg 579, 2010)

C. Gieger, W. Rathmann, J. Pankow, 2011 .

STAT1 gene variations, IgE regulation and atopy

N. Klopp, T. Illig, E. von Mutius, 2007, Allergy.

Genetic variants in Protocadherin‐1, bronchial hyper‐responsiveness, and asthma subphenotypes in German children

N. Klopp, T. Illig, T. Balschun, 2012, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

I. Ntalla, D. Postma, D. Lawlor, 2012, Nature Genetics.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic, Nick C Fox, Michelle K. Lupton, 2019, Nature Genetics.

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss

N. Klopp, T. Illig, C. Holzapfel, 2013, Obesity.

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk

H. Brenner, J. Chang-Claude, M. Hoffmeister, 2010, International journal of cancer.

N. Klopp, T. Illig, H. Grallert, 2008, European journal of endocrinology.

Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms

C. Gieger, J. Pankow, E. Zeggini, 2014, Cell.

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease