N. Carruthers

发表

The first potent and selective non-imidazole human histamine H4 receptor antagonists.

J. A. Jablonowski, Cheryl A. Grice, W. Chai, 2003, Journal of medicinal chemistry.

Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2010, Bioorganic & medicinal chemistry letters.

Indole- and benzothiophene-based histamine H3 antagonists.

Cheryl A. Grice, T. Lovenberg, N. Carruthers, 2010, Bioorganic & medicinal chemistry letters.

Novel imidazole-based histamine H3 antagonists.

J. A. Jablonowski, C. Dvorak, Kiev S. Ly, 2009, Bioorganic & medicinal chemistry letters.

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

2-Aryloxymethylmorpholine histamine H(3) antagonists.

P. Bonaventure, Kiev S. Ly, N. Carruthers, 2008, Bioorganic & medicinal chemistry letters.

Novel human histamine H(3) receptor antagonists.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2002, Bioorganic & medicinal chemistry letters.

A new class of diamine-based human histamine H3 receptor antagonists: 4-(aminoalkoxy)benzylamines.

C. Dvorak, Sandy J. Wilson, T. Lovenberg, 2003, Journal of medicinal chemistry.

Non-imidazole heterocyclic histamine H3 receptor antagonists.

W. Chai, Annette K. Kwok, Sandy J. Wilson, 2003, Bioorganic & medicinal chemistry letters.

Acute wake‐promoting actions of JNJ‐5207852, a novel, diamine‐based H3 antagonist

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2004 .

4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists.

Craig W Berridge, C. Dvorak, Sandy J. Wilson, 2005, Journal of medicinal chemistry.

3,5-Dihydroxybenzoic Acid, a Specific Agonist for Hydroxycarboxylic Acid 1, Inhibits Lipolysis in Adipocytes

T. Lovenberg, N. Carruthers, Jiejun Wu, 2012, Journal of Pharmacology and Experimental Therapeutics.

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [11C]GSK189254 in anesthetized baboon

N. Carruthers, J. Fowler, J. Logan, 2012, Psychopharmacology.

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2015, ACS medicinal chemistry letters.

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, Bioorganic & medicinal chemistry letters.

Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists.

C. Dvorak, T. Lovenberg, N. Carruthers, 2004, Bioorganic & medicinal chemistry letters.

Reductive N‐alkylation of secondary amines with [2‐11C]acetone

J. Leysen, J. A. Jablonowski, N. Carruthers, 2003 .

Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.

T. Lovenberg, N. Carruthers, Hong Ao, 2016, Journal of medicinal chemistry.

Pharmacology of JNJ‐28583113: A novel TRPM2 antagonist

C. Dvorak, T. Lovenberg, N. Carruthers, 2019, European journal of pharmacology.

Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.

P. Bonaventure, J. A. Jablonowski, Kiev S. Ly, 2007, Bioorganic & medicinal chemistry letters.

Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors.

Kiev S. Ly, Sandy J. Wilson, T. Lovenberg, 2007, Bioorganic & medicinal chemistry letters.

Allosteric Modulation of Ionotropic Glutamate Receptors Special Issue.

T. Lovenberg, N. Carruthers, S. Traynelis, 2019, ACS medicinal chemistry letters.

Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, Journal of medicinal chemistry.

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

P. Bonaventure, T. Lovenberg, N. Carruthers, 2011, Psychopharmacology.

Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, European journal of pharmacology.

Synthesis and structure-activity relationships of oxime neurokinin antagonists: discovery of potent arylamides.

Cheryl A. Grice, N. Carruthers, N. Shih, 2002, Bioorganic & medicinal chemistry letters.

Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists.

P. Bonaventure, N. Carruthers, Hong Ao, 2015, Bioorganic & medicinal chemistry letters.

Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists.

N. Carruthers, Hong Ao, A. Bhattacharya, 2015, ACS medicinal chemistry letters.

Tomoxiprole selectively inhibits cyclooxygenase-2.

M. Billah, R. Egan, N. Carruthers, 1997, Prostaglandins.

Patent Update: Pulmonary-Allergy, Dermatological, Gastrointestinal, Endocrine & Metabolic: Highlights from the anti-allergy and gastrointestinal patent literature: July through December 1993

N. Carruthers, J. Kaminski, 1994 .

Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a Small Molecule Antagonist of the Neuropeptide Y Y2 Receptor

P. Bonaventure, J. A. Jablonowski, T. Lovenberg, 2004, Journal of Pharmacology and Experimental Therapeutics.

Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, ACS medicinal chemistry letters.

Translational evaluation of JNJ-18038683, a 5-HT7 receptor antagonist, on REM sleep and in major depressive disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012 .

REM sleep and in major depressive disorder

P. Bonaventure, W. Chai, C. Dvorak, 2012 .

Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore.

J. A. Jablonowski, Kiev S. Ly, Sandy J. Wilson, 2007, Bioorganic & medicinal chemistry letters.

Monthly Update Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Recent developments with investigational drugs potentially useful in the treatment of allergic and inflammatory disorders

N. Carruthers, J. Kaminski, 1995 .

Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia

M. Papp, T. Lovenberg, N. Carruthers, 2018, Neuropsychopharmacology.

4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2017, Journal of medicinal chemistry.

Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonists.

N. Carruthers, Hong Ao, A. Bhattacharya, 2016, Bioorganic & medicinal chemistry letters.

A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334.

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015, European journal of pharmacology.

Neuropharmacology and analgesia A novel radioligand for the ATP-gated ion channel P 2 X 7 : [ 3 H ] JNJ-54232334

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015 .

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists.

P. Bonaventure, N. Carruthers, Hong Ao, 2013, ACS medicinal chemistry letters.

In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor

P. Bonaventure, C. Dvorak, T. Lovenberg, 2010, Psychopharmacology.

Substituted 5,6-(Dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-methanones as P2X7 Antagonists.

P. Bonaventure, T. Lovenberg, N. Carruthers, 2016, ACS chemical neuroscience.

Novel non-peptidic neuropeptide Y Y2 receptor antagonists.

P. Bonaventure, J. A. Jablonowski, W. Chai, 2004, Bioorganic & medicinal chemistry letters.

dantly expressed NPY receptor subtypes in the brain

P. Bonaventure, J. A. Jablonowski, T. Lovenberg, 2004 .

Characterization of JNJ-5207787, a small molecule antagonist of the neuropeptide Y Y 2 receptor

P. Bonaventure, T. Lovenberg, N. Carruthers, 2003 .

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats

E. Levin, P. Bonaventure, T. Lovenberg, 2011, Psychopharmacology.

Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2007, European journal of pharmacology.

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects.

C. Dvorak, T. Lovenberg, N. Carruthers, 2012, ACS medicinal chemistry letters.

Pulmonary-Allergy, Dermatological, Gastrointestinal and Arthritis: Cyclooxygenase-2: a novel target for therapeutic intervention

N. Carruthers, J. Kaminski, R. Aslanian, 1994 .

Discovery and SAR Studies of 2-Alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 Inhibitors Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, Bioorganic & medicinal chemistry letters.

The TRPV1 Vanilloid Receptor: A Target for Therapeutic Intervention

N. Carruthers, S. Chaplan, J. Breitenbucher, 2005 .

Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

Aminophosphonic and aminophosphinic acid analogues of aspartic acid

N. Carruthers, S. Mickel, M. M. Campbell, 1982 .

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

A practical parallel synthesis of 2-substituted indolizines

W. Chai, Annette K. Kwok, N. Carruthers, 2003 .

Synthesis of α-aminophosphonic and α-aminophosphinic acids and derived dipeptides from 4-acetoxyazetidin-2-ones

N. Carruthers, M. M. Campbell, 1980 .

Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.

P. Bonaventure, Kiev S. Ly, Sandy J. Wilson, 2008, Bioorganic & medicinal chemistry letters.

Palladium-catalyzed coupling of pyrazole triflates with arylboronic acids.

C. Dvorak, N. Carruthers, Sandy Ma, 2005, The Journal of organic chemistry.

Recent medicinal chemistry of the histamine H3 receptor.

C. Dvorak, N. Carruthers, Michael A Letavic, 2006, Progress in medicinal chemistry.

Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2009, European journal of medicinal chemistry.

Copper-Mediated Synthesis of Drug-like Bicyclopentanes

N. Carruthers, C. Le, D. MacMillan, 2020, Nature.

.alpha.-Diazophosphonic acids as potential photoaffinity labeling reagents: synthesis, stability, and photochemistry

N. Carruthers, P. Bartlett, B. Winter, 1982 .

Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

N. Carruthers, P. Mantyh, M. Kuskowski, 2005, The Journal of Neuroscience.

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.

J. A. Jablonowski, Cheryl A. Grice, W. Chai, 2005, Journal of medicinal chemistry.

Dual serotonin transporter inhibitor/histamine H3 antagonists: development of rigidified H3 pharmacophores.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

An α-diazophosphonic acid monoester: synthesis, stability, and unexpected photochemical behaviour

N. Carruthers, P. Bartlett, 1982 .

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities.

N. Carruthers, C. Rizzo, S. Wong, 1998, Bioorganic & medicinal chemistry letters.

A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects

T. P. Lebold, P. Bonaventure, T. Lovenberg, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

Nicholas J. Carruthers, J. Pyati, T. Lovenberg, 2001, Molecular pharmacology.

Patent Update Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis Neurokinin receptor antagonists for the treatment of inflammation

N. Carruthers, J. Kaminski, 1996 .

Radiosynthesis and biodistribution of a histamine H3 receptor antagonist 4-[3-(4-piperidin-1-yl-but-1-ynyl)-[11C]benzyl]-morpholine: evaluation of a potential PET ligand.

J. Leysen, J. A. Jablonowski, N. Carruthers, 2006, Nuclear medicine and biology.

Synthesis and resolution of β-(aminomethyl)-4-chlorobenzeneethanesulfinic acid a potent gabaB receptor ligand

N. Carruthers, H. Shue, D. Blythin, 1995 .

Synthesis of corticoids from 9.alpha.-hydroxyandrost-4-ene-3,17-dione

N. Carruthers, A. McPhail, Sohaila Garshasb, 1992 .

A study of 3-amino-N-hydroxypropanesulfonamide derivatives as potential GABAB agonists and their fragmentation to 3-aminopropanesulfinic acid

N. Carruthers, C. Rizzo, H. Shue, 1996 .

Synthesis and Resolution of β-(Aminomethyl)-4- chlorobenzeneethanesulfinic Acid - a Potent GABAB Receptor Ligand.

N. Carruthers, H. Shue, D. Blythin, 1995 .

Discovery of novel nonpeptide tricyclic inhibitors of Ras farnesyl protein transferase.

W. R. Bishop, N. Carruthers, P. Kirschmeier, 1997, Bioorganic & medicinal chemistry.

Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine.

M. Billah, N. Carruthers, A. McPhail, 1999, Bioorganic & medicinal chemistry.

A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate.

C. Dvorak, N. Carruthers, A. Bhattacharya, 2018, Journal of medicinal chemistry.

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

P. Bonaventure, C. Dvorak, T. Lovenberg, 2009, Journal of Pharmacology and Experimental Therapeutics.

Discovery of Imidazo[1,2-a]pyrazines and Pyrazolo[1,5-c]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.

T. Lovenberg, N. Carruthers, B. Savall, 2018, ACS medicinal chemistry letters.

Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.

T. Lovenberg, N. Carruthers, B. Savall, 2018, ACS medicinal chemistry letters.

Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8

T. Lovenberg, N. Carruthers, T. Steckler, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling.

T. Lovenberg, N. Carruthers, S. Bembenek, 2008, Bioorganic & medicinal chemistry.

Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.

N. Carruthers, A. Dubin, Sui-Po Zhang, 2005, Journal of medicinal chemistry.

Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors

P. Bonaventure, N. Carruthers, B. Shireman, 2008 .

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [11C]GSK189254 in anesthetized baboon

N. Carruthers, J. Fowler, J. Logan, 2012, Psychopharmacology.

Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice.

Xavier Langlois, Rene Hen, Pascal Bonaventure, 2002, The Journal of pharmacology and experimental therapeutics.

The discovery of potent selective NPY Y(2) antagonists.

P. Bonaventure, W. Chai, T. Lovenberg, 2013, Bioorganic & medicinal chemistry letters.

Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432

P. Bonaventure, T. Lovenberg, N. Carruthers, 2014, The Journal of Pharmacology and Experimental Therapeutics.

In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor.

Brian Lord, Leah Aluisio, Pascal Bonaventure, 2008, European journal of pharmacology.

Aplysamine-1 and related analogs as histamine H3 receptor antagonists.

T. Lovenberg, N. Carruthers, J. Boggs, 2006, Bioorganic & medicinal chemistry letters.

Effects of histamine H3 antagonists and donepezil on learning and mnemonic deficits induced by pentylenetetrazol kindling in weanling mice

Kazuhiko Yanai, Nobuyuki Okamura, Motohisa Kato, 2006, Neuropharmacology.

Novel Substituted 4‐Phenyl‐[1,3]dioxanes: Potent and Selective Orexin Receptor 2 (OX2R) Antagonists.

C. Dvorak, T. Lovenberg, N. Carruthers, 2004 .

Neurochemical profile of orexin receptor antagonists : awakening the neurochemistry of sleep

P. Bonaventure, C. Dvorak, T. Lovenberg, 2008 .

Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-g 8 s

T. Lovenberg, N. Carruthers, T. Steckler, 2016 .

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2008, Bioorganic & medicinal chemistry letters.

Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”

T. Lovenberg, N. Carruthers, B. Savall, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, ACS Medicinal Chemistry Letters.

Patent Update: Potential Therapeutic Agents for the Treatment of Allergic and Gastrointestinal Disorders

N. Carruthers, J. Kaminski, 1992 .

Patent Update: Novel Chemical Entities Potentially Useful as Allergic and Gastrointestinal Medicaments

N. Carruthers, J. Kaminski, 1992 .

Histamine H3 receptor antagonists: from target identification to drug leads.

P. Bonaventure, F. Kamme, T. Lovenberg, 2007, Biochemical pharmacology.

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012, Journal of Pharmacology and Experimental Therapeutics.

Drug Discovery and Development for Pain

N. Carruthers, S. Chaplan, W. Eckert, 2010 .

1H-Pyrrolo[3,2-b]pyridine GluN2B-Selective Negative Allosteric Modulators.

N. Carruthers, T. Koudriakova, K. Coe, 2019, ACS medicinal chemistry letters.

Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators.

C. Dvorak, N. Carruthers, J. Alcázar, 2023, Journal of medicinal chemistry.

3,5-Dihydroxybenzoic Acid, a Specific Agonist for Hydroxycarboxylic Acid 1, Inhibits Lipolysis in Adipocytes

T. Lovenberg, N. Carruthers, Jiejun Wu, 2012, Journal of Pharmacology and Experimental Therapeutics.

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, Bioorganic & medicinal chemistry letters.

Aplysamine‐1 and Related Analogues as Histamine H3 Receptor Antagonists.

T. Lovenberg, N. Carruthers, J. Boggs, 2006 .

High-Affinity, Non-Peptide Agonists for the ORL 1 (Orphanin FO/Nociceptin) Receptor

N. Carruthers, L. Mcatee, 2002 .

Regioselective assembly of fused pyrazole-azepine heterocycles: Synthesis of the 5-HT7 antagonist 1-benzyl-3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine

C. Dvorak, N. Carruthers, N. Mani, 2021 .