V. de Crécy-Lagard

发表

Consistent alignment of metabolic pathways without abstraction.

Tamer Kahveci, F. Ay, V. de Crécy-Lagard, 2008, Computational systems bioinformatics. Computational Systems Bioinformatics Conference.

Identification of the tRNA-Dihydrouridine Synthase Family*

V. de Crécy-Lagard, P. Schimmel, Reid C. Johnson, 2002, The Journal of Biological Chemistry.

Mining high-throughput experimental data to link gene and function.

V. de Crécy-Lagard, Crysten E. Blaby-Haas, 2011, Trends in biotechnology.

A network approach to elucidate and prioritize microbial dark matter in microbial communities

V. de Crécy-Lagard, A. Conesa, J. Foster, 2020, The ISME journal.

'Unknown' proteins and 'orphan' enzymes: the missing half of the engineering parts list--and how to find it.

V. de Crécy-Lagard, A. Hanson, J. Waller, 2009, The Biochemical journal.

Systematic identification and analysis of frequent gene fusion events in metabolic pathways

Thomas D. Niehaus, V. de Crécy-Lagard, C. Henry, 2016, BMC Genomics.

High-throughput comparison, functional annotation, and metabolic modeling of plant genomes using the PlantSEED resource

Rick L. Stevens, Thomas D. Niehaus, R. Overbeek, 2014, Proceedings of the National Academy of Sciences.

The COMBREX Project: Design, Methodology, and Initial Results

Michael Y. Galperin, S. Salzberg, R. Greiner, 2013, PLoS biology.

Fructose catabolism in Xanthomonas campestris pv. campestris. Sequence of the PTS operon, characterization of the fructose-specific enzymes.

A. Danchin, V. de Crécy-Lagard, P. Lejeune, 1991, Journal of Biological Chemistry.

The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes

Naryttza N. Diaz, Rick L. Stevens, R. Overbeek, 2005, Nucleic acids research.

Identification of the thiamin salvage enzyme thiazole kinase in Arabidopsis and maize.

V. de Crécy-Lagard, A. Hanson, Meral Tunc-Ozdemir, 2013, Phytochemistry.

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

V. de Crécy-Lagard, I. Thiele, Stefanía Magnúsdóttir, 2015, Front. Genet..

Integrative data-mining tools to link gene and function.

V. de Crécy-Lagard, B. El Yacoubi, 2014, Methods in molecular biology.

Deciphering synonymous codons in the three domains of life: Co‐evolution with specific tRNA modification enzymes

V. de Crécy-Lagard, C. Marck, H. Grosjean, 2010, FEBS letters.

Biosynthesis and function of posttranscriptional modifications of transfer RNAs.

V. de Crécy-Lagard, M. Bailly, B. El Yacoubi, 2012, Annual review of genetics.

Essential metabolism for a minimal cell

Zaida Luthey-Schulten, Tyler M Earnest, David J Gonzalez, 2019, eLife.

Functional Annotations of Paralogs: A Blessing and a Curse

Bryan Kolaczkowski, Katherine J. Harrison, Rémi Zallot, 2016, Life.

RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes

Henri Grosjean, Christine Gaspin, Wayne A. Decatur, 2008, BMC Genomics.

Bacterial and plant HAD enzymes catalyse a missing phosphatase step in thiamin diphosphate biosynthesis.

V. de Crécy-Lagard, J. Gregory, A. Hanson, 2016, The Biochemical journal.

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae

E. Koonin, Y. Wolf, K. Makarova, 2015, The Journal of Biological Chemistry.

Finding novel metabolic genes through plant-prokaryote phylogenomics.

V. de Crécy-Lagard, A. Hanson, 2007, Trends in microbiology.

Discovery and Characterization of an Amidinotransferase Involved in the Modification of Archaeal tRNA*♦

V. de Crécy-Lagard, M. Swairjo, D. Iwata‐Reuyl, 2010, The Journal of Biological Chemistry.

Biosynthesis of 7-Deazaguanosine-Modified tRNA Nucleosides: a New Role for GTP Cyclohydrolase I

V. de Crécy-Lagard, S. Alvarez, B. El Yacoubi, 2008, Journal of bacteriology.

A subset of the diverse COG0523 family of putative metal chaperones is linked to zinc homeostasis in all kingdoms of life

V. de Crécy-Lagard, D. Rodionov, S. Merchant, 2009, BMC Genomics.

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB

Scott E. Gabriel, K. Shah, V. de Crécy-Lagard, 2009, Journal of bacteriology.

Towards a Systems Approach in the Genetic Analysis of Archaea: Accelerating Mutant Construction and Phenotypic Analysis in Haloferax volcanii

Ian K. Blaby, V. de Crécy-Lagard, Crysten E. Blaby-Haas, 2010, Archaea.

The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.

Ian K. Blaby, V. de Crécy-Lagard, I. Blaby, 2012, RNA.

Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System.

Eric P. Skaar, D. Giedroc, V. de Crécy-Lagard, 2020, Cell host & microbe.

Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168

V. de Crécy-Lagard, P. Limbach, V. Marchand, 2020, Biomolecules.

Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways

V. de Crécy-Lagard, Geoffrey Hutinet, Manal A Swarjo, 2016, RNA biology.

Evidence That COG0325 Proteins are involved in PLP Homeostasis.

Katherine J. Harrison, O. Fiehn, V. de Crécy-Lagard, 2016, Microbiology.

Novel genomic island modifies DNA with 7-deazaguanine derivatives

V. de Crécy-Lagard, C. Brochier-Armanet, Watthanachai Jumpathong, 2016, Proceedings of the National Academy of Sciences.

Metabolite Damage and Metabolite Damage Control in Plants.

O. Fiehn, V. de Crécy-Lagard, C. Henry, 2016, Annual review of plant biology.

Variations in metabolic pathways create challenges for automated metabolic reconstructions: Examples from the tetrahydrofolate synthesis pathway

V. de Crécy-Lagard, 2014, Computational and structural biotechnology journal.

Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.

V. de Crécy-Lagard, P. Schimmel, M. Swairjo, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Detection of preQ0 deazaguanine modifications in bacteriophage CAjan DNA using Nanopore sequencing reveals same hypermodification at two distinct DNA motifs

V. de Crécy-Lagard, L. Hansen, P. Dedon, 2020, Nucleic acids research.

Identification of genes encoding tRNA modification enzymes by comparative genomics.

V. de Crécy-Lagard, 2007, Methods in enzymology.

Uncovering the chemistry of C–C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex

V. de Crécy-Lagard, J. Naismith, N. Richards, 2020, Chemical communications.

Structure of the ForT/PRPP complex uncovers the mechanism of C-C bond formation in C-nucleotide antibiotic biosynthesis

V. de Crécy-Lagard, J. Naismith, N. Richards, 2020, bioRxiv.

A Genetic Investigation of the KEOPS Complex in Halophilic Archaea

U. Gophna, V. de Crécy-Lagard, T. Allers, 2012, PloS one.

The DUF328 family member YaaA is a DNA-binding protein with a novel fold

V. de Crécy-Lagard, Yilun Liu, Chou-Wei Chang, 2020, The Journal of Biological Chemistry.

Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function

Thomas D. Niehaus, O. Fiehn, V. de Crécy-Lagard, 2018, Bioscience reports.

Identification of the minimal bacterial 2′‐deoxy‐7‐amido‐7‐deazaguanine synthesis machinery

V. de Crécy-Lagard, P. Dedon, D. Iwata‐Reuyl, 2018, Molecular microbiology.

Newly-discovered enzymes that function in metabolite damage-control.

V. de Crécy-Lagard, A. Hanson, Drago Haas, 2018, Current opinion in chemical biology.

The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth*

V. de Crécy-Lagard, Diego Rojas-Benítez, P. Thiaville, 2015, The Journal of Biological Chemistry.

Functions of Bacterial tRNA Modifications: From Ubiquity to Diversity.

V. de Crécy-Lagard, Marshall Jaroch, 2020, Trends in microbiology.

A roadmap for the functional annotation of protein families: a community perspective

Benjamin M. Gyori, Lucy J. Colwell, Ian K. Blaby, 2022, Database J. Biol. Databases Curation.

Mannitol-1-phosphate dehydrogenases/phosphatases: a family of novel bifunctional enzymes for bacterial adaptation to osmotic stress.

V. de Crécy-Lagard, H. Santos, V. Müller, 2015, Environmental microbiology.

Hypermodified DNA in Viruses of E. coli and Salmonella

V. de Crécy-Lagard, P. Weigele, Yan-Jiun Lee, 2021, EcoSal Plus.

Deoxyinosine and 7-Deaza-2-Deoxyguanosine as Carriers of Genetic Information in the DNA of Campylobacter Viruses

C. Szymanski, V. de Crécy-Lagard, P. Azadi, 2019, Journal of Virology.

tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs.

V. de Crécy-Lagard, J. Bujnicki, S. Dunin-Horkawicz, 2016, Methods.

Dihydrouridine in the Transcriptome: New Life for This Ancient RNA Chemical Modification.

V. de Crécy-Lagard, M. Fontecave, D. Hamdane, 2022, ACS chemical biology.

Major Biocontrol of Plant Tumors Targets tRNA Synthetase

J. Reader, V. de Crécy-Lagard, S. Farrand, 2005, Science.

Queuosine modification of tRNA-Tyrosine elicits translational reprogramming and enhances growth of Vibrio cholerae with aminoglycosides

V. de Crécy-Lagard, O. Namy, Z. Baharoglu, 2022, bioRxiv.

Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations

V. de Crécy-Lagard, A. Hanson, B. El Yacoubi, 2007, BMC Genomics.

Functional promiscuity of the COG0720 family.

Robert H. White, V. de Crécy-Lagard, Crysten E. Blaby-Haas, 2012, ACS chemical biology.

Biosynthesis and function of tRNA modifications in Archaea.

V. de Crécy-Lagard, G. Phillips, 2011, Current opinion in microbiology.

An Unusual Route for p-Aminobenzoate Biosynthesis in Chlamydia trachomatis Involves a Probable Self-Sacrificing Diiron Oxygenase

Robert H. White, A. Murzin, V. de Crécy-Lagard, 2020, Journal of Bacteriology.

Archaeosine Modification of Archaeal tRNA: Role in Structural Stabilization

V. de Crécy-Lagard, P. Limbach, R. Schmitz, 2020, Journal of bacteriology.

QueF-Like, a Non-Homologous Archaeosine Synthase from the Crenarchaeota

V. de Crécy-Lagard, D. Iwata‐Reuyl, Ben Turner, 2017, Biomolecules.

The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12

Thomas J. Begley, A. Danchin, V. de Crécy-Lagard, 2022, Metallomics : integrated biometal science.

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

V. de Crécy-Lagard, F. Musayev, M. Safo, 2022, Protein science : a publication of the Protein Society.

Whole-Genome Sequence of Streptomyces kaniharaensis Shomura and Niida SF-557

V. de Crécy-Lagard, N. Richards, M. Hughes, 2020, Microbiology Resource Announcements.

Decoding in Candidatus Riesia pediculicola, close to a minimal tRNA modification set?

V. de Crécy-Lagard, C. Marck, H. Grosjean, 2012, Trends in cell & molecular biology.

Synergistic use of plant-prokaryote comparative genomics for functional annotations

Andreas Wilke, Ross Overbeek, Ian K. Blaby, 2011, BMC Genomics.

Plant B vitamin pathways and their compartmentation: a guide for the perplexed.

Svetlana Gerdes, Andrew D Hanson, Christopher S Henry, 2012, Journal of experimental botany.

Identification of Mitochondrial Coenzyme A Transporters from Maize and Arabidopsis1[W][OA]

V. de Crécy-Lagard, R. Mullen, Claudia Lerma-Ortiz, 2013, Plant Physiology.

Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family

V. de Crécy-Lagard, D. Hamdane, D. Brégeon, 2022, Biomolecules.

Phylogenomic and Functional Analysis of Pterin-4a-Carbinolamine Dehydratase Family (COG2154) Proteins in Plants and Microorganisms1[W][OA]

V. de Crécy-Lagard, S. Beverley, S. Ravanel, 2008, Plant Physiology.

Diversity of archaeosine synthesis in crenarchaeota.

V. de Crécy-Lagard, M. Bailly, P. Limbach, 2012, ACS chemical biology.

A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis.

Bing Wang, James G. Jeffryes, James G Jeffryes, 2015, The Biochemical journal.

Systematic identification and analysis of frequent gene fusion events in metabolic pathways

Thomas D. Niehaus, V. de Crécy-Lagard, C. Henry, 2016, BMC Genomics.

Experimental Evolution of a Facultative Thermophile from a Mesophilic Ancestor

Ian K. Blaby, Steven A. Benner, S. Benner, 2011, Applied and Environmental Microbiology.

Incorporation of nonnatural amino acids into proteins.

Paul Schimmel, Tamara L Hendrickson, V. de Crécy-Lagard, 2004, Annual review of biochemistry.

Metabolite Damage and Damage Control in a Minimal Genome

Lijie Sun, K. Wise, J. Glass, 2021, bioRxiv.

Complete Reconstitution of the Human Coenzyme A Biosynthetic Pathway via Comparative Genomics*

Athanasios Lykidis, V. de Crécy-Lagard, A. Osterman, 2002, The Journal of Biological Chemistry.

From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold.

J. Reader, V. de Crécy-Lagard, M. Swairjo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of a Gene Family Critical to Wyosine Base Formation in a Subset of Phenylalanine-specific Transfer RNAs*

V. de Crécy-Lagard, P. Schimmel, W. Waas, 2005, Journal of Biological Chemistry.

Global translational impacts of the loss of the tRNA modification t6A in yeast

V. de Crécy-Lagard, O. Namy, G. Chalancon, 2015, Microbial cell.

Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.

V. de Crécy-Lagard, J. Armengaud, L. Droogmans, 2010, Molecular biology and evolution.

Rapid Evolution of Diminished Transformability in Acinetobacter baylyi

D. Metzgar, V. de Crécy-Lagard, Jamie M. Bacher, 2006, Journal of bacteriology.

Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5′-monophosphate as the biological substrate

Gregory I. Elliott, V. de Crécy-Lagard, B. Green, 2023, Nucleic acids research.

Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens

V. de Crécy-Lagard, J. Gerlt, S. Almo, 2019, Proceedings of the National Academy of Sciences.

Plant, Animal, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family

V. de Crécy-Lagard, F. Forouhar, J. Hunt, 2014, ACS chemical biology.

Discovery of the β-barrel–type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs

V. de Crécy-Lagard, Tsutomu Suzuki, K. Miyauchi, 2014, Nucleic acids research.

PMP–diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9cc06975e

V. de Crécy-Lagard, J. Naismith, N. Richards, 2019, Chemical communications.

Can Protein Expression Be Regulated by Modulation of tRNA Modification Profiles?

V. de Crécy-Lagard, Leticia Pollo-Oliveira, 2018, Biochemistry.

Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t6A), a universal modification of tRNA

V. de Crécy-Lagard, P. Thiaville, D. Iwata-Reuyl, 2014, RNA biology.

Biosynthesis of Threonylcarbamoyl Adenosine (t6A), a Universal tRNA Nucleoside*

V. de Crécy-Lagard, B. El Yacoubi, D. Iwata-Reuyl, 2012, The Journal of Biological Chemistry.

A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification

Tamer Kahveci, V. de Crécy-Lagard, J. Rousset, 2011, The EMBO journal.

'Nothing of chemistry disappears in biology': the Top 30 damage-prone endogenous metabolites.

Oliver Fiehn, James G. Jeffryes, Thomas D. Niehaus, 2016, Biochemical Society transactions.

Role of a Zn‐independent DksA in Zn homeostasis and stringent response

V. de Crécy-Lagard, Crysten E. Blaby-Haas, D. Rodionov, 2011, Molecular microbiology.

Artificially ambiguous genetic code confers growth yield advantage.

P. Marlière, D. Metzgar, V. de Crécy-Lagard, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A Gateway platform for functional genomics in Haloferax volcanii: deletion of three tRNA modification genes.

Ian K. Blaby, V. de Crécy-Lagard, I. Blaby, 2009, Archaea.

Predicting the Minimal Translation Apparatus: Lessons from the Reductive Evolution of Mollicutes

V. de Crécy-Lagard, D. Fourmy, A. Blanchard, 2014, PLoS genetics.

Predicting the pathway involved in post-translational modification of Elongation factor P in a subset of bacterial species

V. de Crécy-Lagard, M. Bailly, 2010, Biology Direct.

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast

Thomas J. Begley, V. de Crécy-Lagard, T. Begley, 2020, Biomolecules.

Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy.

V. de Crécy-Lagard, P. Clayton, V. Crécy-Lagard, 2016, American journal of human genetics.

Moonlighting Glutamate Formiminotransferases Can Functionally Replace 5-Formyltetrahydrofolate Cycloligase*

V. de Crécy-Lagard, J. Gregory, A. Hanson, 2010, The Journal of Biological Chemistry.

tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii

V. de Crécy-Lagard, Priti Thakur, Manasses Jora, 2019, Journal of bacteriology.

7-Deazaguanine modifications protect phage DNA from host restriction systems

V. de Crécy-Lagard, L. Hansen, M. Sassanfar, 2019, Nature Communications.

Identification of a Novel Epoxyqueuosine Reductase Family by Comparative Genomics

Rémi Zallot, Wei-Hung Chen, V. de Crécy-Lagard, 2017, ACS chemical biology.

Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars

Matthew P Jacobson, Suwen Zhao, Brian San Francisco, 2016, Proceedings of the National Academy of Sciences.

Pseudouridine formation in archaeal RNAs: The case of Haloferax volcanii.

Ian K. Blaby, V. de Crécy-Lagard, I. Blaby, 2011, RNA.

A strictly monofunctional bacterial hydroxymethylpyrimidine phosphate kinase precludes damaging errors in thiamin biosynthesis.

V. de Crécy-Lagard, S. Gerdes, A. Hanson, 2017, The Biochemical journal.

Discovery of a New Prokaryotic Type I GTP Cyclohydrolase Family*

Manal A. Swairjo, V. de Crécy-Lagard, M. Swairjo, 2006, Journal of Biological Chemistry.

Pyridoxal 5’-phosphate synthesis and salvage in Bacteria and Archaea: predicting pathway variant distributions and holes

V. de Crécy-Lagard, J. Gerlt, R. Denise, 2023, Microbial genomics.

Comparative RNomics and Modomics in Mollicutes: Prediction of Gene Function and Evolutionary Implications

V. de Crécy-Lagard, C. Brochier-Armanet, C. Marck, 2007, IUBMB life.

Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.

V. de Crécy-Lagard, S. Gerdes, J. Hunt, 2014, The Biochemical journal.

The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA

V. de Crécy-Lagard, P. Schimmel, J. Williamson, 2009, Nucleic acids research.

Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite.

O. Fiehn, S. Copley, V. de Crécy-Lagard, 2016, ACS chemical biology.

Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes

V. de Crécy-Lagard, M. Fontecave, D. Hamdane, 2021, RNA biology.

Knowns and Unknowns of Vitamin B6 Metabolism in Escherichia coli

V. de Crécy-Lagard, C. Nardella, A. Tramonti, 2021, EcoSal Plus.

Comparative Genomic Analysis of the DUF34 Protein Family Suggests Role as a Metal Ion Chaperone or Insertase

V. de Crécy-Lagard, Geoffrey Hutinet, C. Reed, 2021, Biomolecules.

Cross Kingdom Functional Conservation of the Core Universally Conserved Threonylcarbamoyladenosine tRNA Synthesis Enzymes

V. de Crécy-Lagard, P. Forterre, O. Namy, 2014, Eukaryotic Cell.

Epoxyqueuosine Reductase QueH in the Biosynthetic Pathway to tRNA Queuosine Is a Unique Metalloenzyme.

V. de Crécy-Lagard, J. Gerlt, A. Angerhofer, 2021, Biochemistry.

Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of Escherichia coli

Philippe Marlière, P. Marlière, V. de Crécy-Lagard, 2001, BMC biotechnology.

Enlarging the Amino Acid Set of Escherichia coli by Infiltration of the Valine Coding Pathway

P. Marlière, V. de Crécy-Lagard, H. Mootz, 2001, Science.

Open access, freely available online PLoS BIOLOGY Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance

Floyd E Romesberg, William A Craig, V. de Crécy-Lagard, 2022 .

The Response of Acinetobacter baumannii to Zinc Starvation.

Eric P. Skaar, D. Giedroc, V. de Crécy-Lagard, 2016, Cell host & microbe.

6-Pyruvoyltetrahydropterin Synthase Paralogs Replace the Folate Synthesis Enzyme Dihydroneopterin Aldolase in Diverse Bacteria

J. E. Hyde, V. de Crécy-Lagard, A. Hanson, 2009, Journal of bacteriology.

FolX and FolM Are Essential for Tetrahydromonapterin Synthesis in Escherichia coli and Pseudomonas aeruginosa

Ian K. Blaby, V. de Crécy-Lagard, J. Gregory, 2009, Journal of bacteriology.

A network approach to elucidate and prioritize microbial dark matter in microbial communities

V. de Crécy-Lagard, A. Conesa, J. Foster, 2020, The ISME Journal.

Experimental and Metabolic Modeling Evidence for a Folate-Cleaving Side-Activity of Ketopantoate Hydroxymethyltransferase (PanB)

Andrew D. Hanson, Christopher S. Henry, Katherine J. Harrison, 2016, Front. Microbiol..

Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea

Ian K. Blaby, Daniel N. Wilson, V. de Crécy-Lagard, 2016, Archaea.

The Escherichia coli COG1738 Member YhhQ Is Involved in 7-Cyanodeazaguanine (preQ0) Transport

V. de Crécy-Lagard, Rémi Zallot, Yifeng Yuan, 2017, Biomolecules.

Specificity in the biosynthesis of the universal tRNA nucleoside N6-threonylcarbamoyl adenosine (t6A)—TsaD is the gatekeeper

V. de Crécy-Lagard, A. Luthra, P. Agris, 2020, RNA.

Proteins of Unknown Biochemical Function: A Persistent Problem and a Roadmap to Help Overcome It1

Thomas D. Niehaus, Andrew D Hanson, V. de Crécy-Lagard, 2015, Plant Physiology.

Molecular determinants of dihydrouridine synthase activity

V. de Crécy-Lagard, A. Bishop, D. Savage, 2006, FEBS letters.

Aminoacylation of the anticodon stem by a tRNA-synthetase paralog: relic of an ancient code?

V. de Crécy-Lagard, G. Björk, H. Grosjean, 2004, Trends in biochemical sciences.

Identification of Four Genes Necessary for Biosynthesis of the Modified Nucleoside Queuosine*

D. Metzgar, J. Reader, V. de Crécy-Lagard, 2004, Journal of Biological Chemistry.

Quinolinate Salvage and Insights for Targeting NAD Biosynthesis in Group A Streptococci

Ian K. Blaby, V. de Crécy-Lagard, A. Osterman, 2012, Journal of bacteriology.

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes

V. de Crécy-Lagard, M. Graille, Nathalie Ulryck, 2018, Nucleic acids research.

Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs

T. Lenstra, P. Lijnzaad, F. Holstege, 2011, Nucleic acids research.

A family of metal-dependent phosphatases implicated in metabolite damage-control.

Oliver Fiehn, John Shanklin, Rémi Zallot, 2016, Nature chemical biology.

Genome Sequence of Candidatus Riesia pediculischaeffi, Endosymbiont of Chimpanzee Lice, and Genomic Comparison of Recently Acquired Endosymbionts from Human and Chimpanzee Lice

Julie M. Allen, V. de Crécy-Lagard, D. Reed, 2014, G3: Genes, Genomes, Genetics.

ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities.

S. Gottesman, V. de Crécy-Lagard, V. Crécy-Lagard, 1993, The Journal of biological chemistry.

Alteration of the synthesis of the Clp ATP‐dependent protease affects morphological and physiological differentiation in Streptomyces

V. de Crécy-Lagard, C. Grandvalet, P. Mazodier, 1999, Molecular microbiology.

Discovery of a widespread prokaryotic 5-oxoprolinase that was hiding in plain sight

Thomas D. Niehaus, O. Fiehn, V. de Crécy-Lagard, 2017, The Journal of Biological Chemistry.

A Xanthomonas campestris pv. campestris protein similar to catabolite activation factor is involved in regulation of phytopathogenicity

A. Danchin, V. de Crécy-Lagard, P. Glaser, 1990, Journal of bacteriology.

Acinetobacter sp. ADP1: an ideal model organism for genetic analysis and genome engineering.

Philippe Marlière, Paul Schimmel, David Metzgar, 2004, Nucleic acids research.

Promiscuous and Adaptable Enzymes Fill “Holes” in the Tetrahydrofolate Pathway in Chlamydia Species

V. de Crécy-Lagard, F. Barona-Gómez, A. J. McCoy, 2014, mBio.

Fructose phosphotransferase system of Xanthomonas campestris pv. campestris: characterization of the fruB gene.

A. Danchin, V. de Crécy-Lagard, M. Binet, 1995, Microbiology.

Quantitative mapping of the cellular small RNA landscape with AQRNA-seq

Thomas J. Begley, V. de Crécy-Lagard, S. Levine, 2021, Nature Biotechnology.

Sequencing-based quantitative mapping of the cellular small RNA landscape

V. de Crécy-Lagard, S. Levine, M. DeMott, 2019, bioRxiv.

The ClpB ATPase of Streptomyces albus G belongs to the HspR heat shock regulon

V. de Crécy-Lagard, C. Grandvalet, P. Mazodier, 1999, Molecular microbiology.

Identification and Characterization of the Missing Pyrimidine Reductase in the Plant Riboflavin Biosynthesis Pathway1[W][OA]

V. de Crécy-Lagard, J. Gregory, A. Hanson, 2012, Plant Physiology.

Multienzymatic non ribosomal peptide biosynthesis: identification of the functional domains catalysing peptide elongation and epimerisation.

P. Marlière, W. Saurin, V. de Crécy-Lagard, 1995, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life

Ian K. Blaby, V. de Crécy-Lagard, T. Vickers, 2010, Proceedings of the National Academy of Sciences.

A plastidial pantoate transporter with a potential role in pantothenate synthesis.

V. de Crécy-Lagard, C. Henry, A. Fernie, 2018, The Biochemical journal.

4′-Deoxypyridoxine disrupts vitamin B6 homeostasis in Escherichia coli K12 through combined inhibition of cumulative B6 uptake and PLP-dependent enzyme activity

A. Deutschbauer, V. de Crécy-Lagard, C. Nardella, 2023, Microbiology.

Bacterial RNA Degradosomes: Molecular Machines under Tight Control.

V. de Crécy-Lagard, H. de Reuse, Alejandro Tejada-Arranz, 2020, Trends in biochemical sciences.

Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene

W. Saurin, V. de Crécy-Lagard, J. Crouzet, 1997, Antimicrobial agents and chemotherapy.

Plasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?

J. E. Hyde, V. de Crécy-Lagard, A. Hanson, 2008, Trends in parasitology.

Mutational separation of two pathways for editing by a class I tRNA synthetase.

Paul Schimmel, Shigeyuki Yokoyama, Osamu Nureki, 2002, Molecular cell.

7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system

V. de Crécy-Lagard, A. Luthra, P. Dedon, 2023, Nucleic acids research.

Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase.

V. de Crécy-Lagard, P. Schimmel, Jamie M. Bacher, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Genetic Code Ambiguity Confers a Selective Advantage on Acinetobacter baylyi

D. Metzgar, V. de Crécy-Lagard, P. Schimmel, 2007, Journal of bacteriology.

Four additional natural 7-deazaguanine derivatives in phages and how to make them

V. de Crécy-Lagard, K. Holmfeldt, P. Weigele, 2023, bioRxiv.

Pristinamycin I biosynthesis in Streptomyces pristinaespiralis: molecular characterization of the first two structural peptide synthetase genes

V. de Crécy-Lagard, J. Crouzet, V. Blanc, 1997, Journal of bacteriology.

Beyond Blast: Enabling Microbiologists to Better Extract Literature, Taxonomic Distributions and Gene Neighborhood Information for Protein Families

V. de Crécy-Lagard, Geoffrey Hutinet, R. Denise, 2023, bioRxiv.

The Escherichia coli COG1738 Member YhhQ Is Involved in 7-Cyanodeazaguanine (preQ0) Transport

Yuri Motorin, Mark Helm, Lilia Ayadi, 2017, Biomolecules.

Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage

V. de Crécy-Lagard, L. Tong, F. Forouhar, 2012, Biology Direct.

Experimental Evolution of a Facultative Thermophile from a Mesophilic Ancestor

Ian K. Blaby, S. Benner, V. de Crécy-Lagard, 2011, Applied and Environmental Microbiology.

Evidence That COG0325 Proteins are involved in PLP Homeostasis.

Katherine J. Harrison, O. Fiehn, V. de Crécy-Lagard, 2016, Microbiology.

Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages.

V. de Crécy-Lagard, M. Chevrette, Rémi Zallot, 2024, Microbiology and molecular biology reviews : MMBR.

Alternate routes to mnm5s2U synthesis in Gram-positive bacteria

V. de Crécy-Lagard, Kelly C. Rice, Agnieszka Dziergowska, 2024, Journal of bacteriology.

Arabidopsis TH2 Encodes the Orphan Enzyme Thiamin Monophosphate Phosphatase[OPEN]

Thomas D. Niehaus, V. de Crécy-Lagard, J. Gregory, 2016, Plant Cell.