J. Chan

V. Cheng, J. Chan, K. To, 2013, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant

K. To, Jian-Piao Cai, J. Chan, 2022, Cell discovery.

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Nature communications.

Prevention of nosocomial transmission of swine-origin pandemic influenza virus A/H1N1 by infection control bundle

K. To, Kwok-Hung Chan, J. Chan, 2010, Journal of Hospital Infection.

Complementary use of MALDI-TOF MS and real-time PCR-melt curve analysis for rapid identification of methicillin-resistant staphylococci and VRE.

J. Chan, B. S. Tang, R. Lai, 2015, Journal of Antimicrobial Chemotherapy.

Fusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants

K. To, J. Chan, K. Yuen, 2022, Emerging microbes & infections.

A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamsters

K. To, J. Chan, K. Yuen, 2022, Cell discovery.

Ongoing transmission of avian influenza A viruses in Hong Kong despite very comprehensive poultry control measures: A prospective seroepidemiology study.

K. To, Kwok-Hung Chan, J. Chan, 2016, The Journal of infection.

Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses

K. To, C. Yip, Kwok-Hung Chan, 2015, Journal of Clinical Microbiology.

Title Avian Influenza A H 7 N 9 Virus Induces Severe Pneumonia in Mice without Prior Adaptation and Responds to a Combination of Zanamivir and COX-2 Inhibitor

K. To, J. Chan, I. Hung, 2014 .

Avian Influenza A H7N9 Virus Induces Severe Pneumonia in Mice without Prior Adaptation and Responds to a Combination of Zanamivir and COX-2 Inhibitor

K. To, J. Chan, I. Hung, 2014, PloS one.

Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus

K. To, Kwok-Hung Chan, J. Chan, 2013, Journal of Infection.

The Lower Serum Immunoglobulin G2 Level in Severe Cases than in Mild Cases of Pandemic H1N1 2009 Influenza Is Associated with Cytokine Dysregulation

K. To, Kwok-Hung Chan, V. Cheng, 2010, Clinical and Vaccine Immunology.

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

K. To, Jian-Piao Cai, J. Chan, 2020, Cell Reports Medicine.

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

K. To, C. Yip, Jian-Piao Cai, 2022, Science.

The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model

K. To, C. Yip, Jian-Piao Cai, 2022, bioRxiv.

Emerging SARS-CoV-2 variants expand species tropism to rodents

K. To, Jian-Piao Cai, W. Chan, 2021 .

Fatal Empyema Thoracis Caused by Schizophyllum commune with Cross-Reactive Cryptococcal Antigenemia

K. To, J. Chan, K. Yuen, 2013, Journal of Clinical Microbiology.

Targeting the inositol-requiring enzyme-1 pathway efficiently reverts Zika virus-induced neurogenesis and spermatogenesis marker perturbations.

J. Chan, K. Yuen, Jie Zhou, 2020, ACS infectious diseases.

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B‐NS3 protease inhibitor

C. Yip, Kwok-Hung Chan, J. Chan, 2017, Antiviral research.

Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages

K. To, Jian-Piao Cai, J. Chan, 2019, The Journal of infectious diseases.

The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”

J. Chan, S. Lau, Patrick C Y Woo, 2013, Journal of the Formosan Medical Association.

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis

J. Chan, K. Yuen, Jie Zhou, 2015, Virology Journal.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome Coronavirus

J. Chan, K. Yuen, G. Gao, 2016, Journal of Virology.

Coronaviruses: emerging and re-emerging pathogens in humans and animals

J. Chan, S. Lau, 2015, Virology Journal.

Emergence of Cytomegalovirus Mononucleosis Syndrome Among Young Adults in Hong Kong Linked to Falling Seroprevalence: Results of a 14-Year Seroepidemiological Study

P. Woo, V. Cheng, J. Chan, 2018, Open forum infectious diseases.

A Systematic Approach to Novel Virus Discovery in Emerging Infectious Disease Outbreaks

P. Woo, K. To, J. Chan, 2015, The Journal of Molecular Diagnostics.

SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission 1 in hamsters 2

Kwok-Hung Chan, J. Chan, Honglin Chen, 2020 .

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

K. To, Jian-Piao Cai, W. Chan, 2020, Nature Communications.

Clostridium difficile isolates with increased sporulation: emergence of PCR ribotype 002 in Hong Kong

W. Yam, K. To, V. Cheng, 2011, European Journal of Clinical Microbiology & Infectious Diseases.

Outbreak of Intestinal Infection Due to Rhizopus microsporus

V. Cheng, J. Chan, K. Yuen, 2009, Journal of Clinical Microbiology.

Proactive infection control measures to prevent nosocomial transmission of carbapenem‐resistant Enterobacteriaceae in a non‐endemic area

K. To, V. Cheng, J. Chan, 2013, Chinese medical journal.

Severe influenza A H7N9 pneumonia with rapid virological response to intravenous zanamivir

Kwok-Hung Chan, V. Cheng, J. Chan, 2014, European Respiratory Journal.

Analytical Sensitivity of Seven Point-of-Care Influenza Virus Detection Tests and Two Molecular Tests for Detection of Avian Origin H7N9 and Swine Origin H3N2 Variant Influenza A Viruses

K. To, Kwok-Hung Chan, J. Chan, 2013, Journal of Clinical Microbiology.

Prevention of Nosocomial Transmission of Norovirus by Strategic Infection Control Measures

K. To, V. Cheng, J. Chan, 2011, Infection Control & Hospital Epidemiology.

Development and in-use evaluation of a novel Luminex MicroPlex microsphere-based (TRIOL) assay for simultaneous identification of Mycobacterium tuberculosis and detection of first-line and second-line anti-tuberculous drug resistance in China

J. Chan, K. Yuen, W. Yam, 2016, Journal of Clinical Pathology.

Human H7N9 virus induces a more pronounced pro-inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically-linked chicken H7N9 virus

K. To, Kwok-Hung Chan, J. Chan, 2016, Virology Journal.

Title Human H 7 N 9 virus induces a more pronounced pro-inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically-linked chicken H 7 N 9 virus

K. To, Kwok-Hung Chan, J. Chan, 2016 .

Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial.

K. To, Kwok-Hung Chan, J. Chan, 2016, The Lancet. Infectious diseases.

A 10-year study reveals clinical and laboratory evidence for the ‘semi-invasive' properties of chronic pulmonary aspergillosis

Siu Man Chan, K. To, V. Cheng, 2016, Emerging Microbes & Infections.

Genetic diversity of Aspergillus species isolated from onychomycosis and Aspergillus hongkongensis sp. nov., with implications to antifungal susceptibility testing.

J. Chan, K. Yuen, Kim-Chung Lee, 2016, Diagnostic microbiology and infectious disease.

Subcutaneous Phaeohyphomycotic Nodule Due to Phialemoniopsis hongkongensis sp. nov

J. Chan, P. Ip, S. Lau, 2014, Journal of Clinical Microbiology.

Streptobacillus hongkongensis sp. nov., isolated from patients with quinsy and septic arthritis, and emended descriptions of the genus Streptobacillus and Streptobacillus moniliformis.

P. Woo, J. Chan, S. Lau, 2014, International journal of systematic and evolutionary microbiology.

Clinical Spectrum of Exophiala Infections and a Novel Exophiala Species, Exophiala hongkongensis

P. Woo, J. Chan, K. Yuen, 2012, Journal of Clinical Microbiology.

Internal Transcribed Spacer Region Sequence Heterogeneity in Rhizopus microsporus: Implications for Molecular Diagnosis in Clinical Microbiology Laboratories

P. Woo, K. To, V. Cheng, 2009, Journal of Clinical Microbiology.

SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters

Kenneth Lap-Kei Wu, Jian-Piao Cai, J. Chan, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Rapid reduction of viruria and stabilization of allograft function by fusidic acid in a renal transplant recipient with JC virus-associated nephropathy

Kwok-Hung Chan, V. Cheng, J. Chan, 2015, Infection.

Avian-origin influenza A(H7N9) infection in influenza A(H7N9)-affected areas of China: a serological study.

K. To, J. Chan, Honglin Chen, 2014, The Journal of infectious diseases.

Use of fluoroquinolones is the single most important risk factor for the high bacterial load in patients with nasal and gastrointestinal colonization by multidrug-resistant Acinetobacter baumannii

J. H. Chen, V. Cheng, J. Chan, 2015, European Journal of Clinical Microbiology and Infectious Diseases.

Clostridium difficile ribotype 027 arrives in Hong Kong.

K. To, J. Chan, K. Yuen, 2009, International journal of antimicrobial agents.

Minimal Intervention for Controlling Nosocomial Transmission of Methicillin-Resistant Staphylococcus aureus in Resource Limited Setting with High Endemicity

K. To, V. Cheng, J. Chan, 2014, PloS one.

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells

J. Chan, Jie Zhou, H. Chu, 2021, Emerging microbes & infections.

Targeting ACLY efficiently inhibits SARS-CoV-2 replication

Jian-Piao Cai, J. Chan, H. Chu, 2022, International journal of biological sciences.

Host genes and influenza pathogenesis in humans: an emerging paradigm

J. Chan, K. Yuen, Jie Zhou, 2015, Current Opinion in Virology.

Renal denervation superior to drug therapy in hypertension

J. Chan, K. Yuen, C. Yu, 2015 .

An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron

J. Chan, K. Yuen, H. Chu, 2022, Nature Microbiology.

Absence of nosocomial influenza and respiratory syncytial virus infection in the coronavirus disease 2019 (COVID-19) era: Implication of universal masking in hospitals

V. Cheng, J. Chan, I. Hung, 2020, Infection Control & Hospital Epidemiology.

Cutaneous hyalohyphomycosis due to Parengyodontium album gen. et comb. nov.

P. Woo, J. Chan, S. Lau, 2016, Medical mycology.

Reactive and Infective Dermatoses Associated with Adult-Onset Immunodeficiency due to Anti-Interferon-Gamma Autoantibody: Sweet's Syndrome and Beyond

V. Cheng, J. Chan, I. Hung, 2013, Dermatology.

Disseminated Penicilliosis, Recurrent Bacteremic Nontyphoidal Salmonellosis, and Burkholderiosis Associated with Acquired Immunodeficiency Due to Autoantibody against Gamma Interferon

O. Tsang, K. To, V. Cheng, 2010, Clinical and Vaccine Immunology.

An unprecedented outbreak investigation for nosocomial and community-acquired legionellosis in Hong Kong.

Samson S. Y. Wong, K. To, Kwok-Hung Chan, 2012, Chinese medical journal.

Extensive contact tracing and screening to control the spread of vancomycin-resistant Enterococcus faecium ST414 in Hong Kong.

V. Cheng, J. Chan, K. Yuen, 2012, Chinese medical journal.

Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping.

K. To, C. Yip, V. Cheng, 2018, Diagnostic microbiology and infectious disease.

Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model

K. To, D. Lung, C. Yip, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Toll-Like Receptor 7 Agonist Imiquimod in Combination with Influenza Vaccine Expedites and Augments Humoral Immune Responses against Influenza A(H1N1)pdm09 Virus Infection in BALB/c Mice

K. To, J. Chan, I. Hung, 2014, Clinical and Vaccine Immunology.

First detection and complete genome sequence of a phylogenetically distinct human polyomavirus 6 highly prevalent in human bile samples.

Kwok-Hung Chan, R. W. Poon, J. Chan, 2017, The Journal of infection.

A case series of children with Coronavirus Disease 2019: what have we learned?

K. To, J. Chan, K. Yuen, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses

J. Chan, Jie Zhou, H. Chu, 2021, Biomedicines.

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells

J. Chan, K. Yuen, H. Chu, 2020, Metabolites.

Human tryptophanyl-tRNA synthetase is an IFN-&ggr;–inducible entry factor for Enterovirus

P. Woo, Jian-Piao Cai, Kwok-Hung Chan, 2018, The Journal of clinical investigation.

Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron

K. To, Jian-Piao Cai, J. Chan, 2021, Nature.

Endosomal acidification inhibitors broadly inhibit influenza virus and coronavirus in vivo

K. To, J. Chan, K. Yuen, 2021 .

Peptidic defective interfering gene nanoparticles against Omicron, Delta SARS-CoV-2 variants and influenza A virus in vivo

J. Chan, K. Yuen, Hanjun Zhao, 2022, Signal Transduction and Targeted Therapy.

Epidemiological and Clinical Characteristics of Human Hepegivirus 1 Infection in Patients With Hepatitis C

C. Yip, V. Cheng, J. Chan, 2019, Open forum infectious diseases.

Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway

A. Tam, Jian-Piao Cai, Kwok-Hung Chan, 2022, International journal of biological sciences.

Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay

J. Chan, J. Perfect, N. Thu, 2020, Open forum infectious diseases.

Superiority of a Novel Mp1p Antigen Detection Enzyme Immunoassay Compared to Standard BACTEC Blood Culture in the Diagnosis of Talaromycosis

N. P. H. Lan, Jian-Piao Cai, J. Chan, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Transmission of Rat Hepatitis E Virus Infection to Humans in Hong Kong: A Clinical and Epidemiological Analysis

O. Tsang, C. Yip, Jian-Piao Cai, 2020, Hepatology.

First Report of Brain Abscess Caused by a Satelliting Phenotypic Variant of Helcococcus kunzii

J. Chan, K. Yuen, S. Sridhar, 2013, Journal of Clinical Microbiology.

Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus

C. Yip, Kwok-Hung Chan, V. Cheng, 2018, Virology Journal.

The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Emerging microbes & infections.

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

C. Yip, Jian-Piao Cai, Kwok-Hung Chan, 2016, Emerging Microbes & Infections.

Successful control of vancomycin-resistant Enterococcus faecium outbreak in a neurosurgical unit at non-endemic region

J. Chan, K. Yuen, K. To, 2008 .

The use of high-resolution melting analysis for rapid spa typing on methicillin-resistant Staphylococcus aureus clinical isolates.

V. Cheng, J. Chan, K. Yuen, 2013, Journal of microbiological methods.

Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus

Jian-Piao Cai, J. Chan, K. Yuen, 2019, Viruses.

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy

C. Yip, J. Chan, K. Yuen, 2018, Antiviral Research.

Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models

C. Yip, Jian-Piao Cai, Kwok-Hung Chan, 2018, The Journal of infectious diseases.

Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

Jian-Piao Cai, J. Chan, K. Yuen, 2017, Journal of Virology.

Molecular Characterization of a Catalase-Negative Staphylococcus aureus subsp. aureus Strain Collected from a Patient with Mitral Valve Endocarditis and Pericarditis Revealed a Novel Nonsense Mutation in the katA Gene

K. To, V. Cheng, J. Chan, 2011, Journal of Clinical Microbiology.

Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters.

Jian-Piao Cai, Kwok-Hung Chan, Cuiting Luo, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Targeting papain-like protease for broad-spectrum coronavirus inhibition

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Protein & Cell.

Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong

K. To, C. Yip, Kwok-Hung Chan, 2020, Journal of Clinical Microbiology.

Clinical performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 1 detection in nasopharyngeal specimens of COVID-19 patients in Hong Kong a commercial detection

K. To, C. Yip, Kwok-Hung Chan, 2020 .

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant

P. Woo, C. Yip, Jian-Piao Cai, 2018, Emerging infectious diseases.

Reply to Leow

Kwok-Hung Chan, J. Chan, K. Yuen, 2013, The Journal of infectious diseases.

Evaluation of the molecular Xpert Xpress Flu/RSV assay vs. Alere i Influenza A & B assay for rapid detection of influenza viruses.

J. H. Chen, J. Chan, K. Yuen, 2017, Diagnostic microbiology and infectious disease.

Human oropharynx as natural reservoir of Streptobacillus hongkongensis

P. Woo, J. Chan, Y. Lau, 2016, Scientific Reports.

Mixed genotypes of Orientia tsutsugamushi in conserved genes and a single immune-dominant tsa56 genotype discovered from a patient with scrub typhus in Hainan Island, China: a case report

J. Chan, K. Yuen, Y. Huang, 2022, BMC Infectious Diseases.

Bacillus Calmette-Guérin–induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice

Jian-Piao Cai, J. Chan, I. Hung, 2022, JCI insight.

Early treatment of high-risk hospitalized COVID-19 patients with a combination of interferon beta-1b and remdesivir: a phase 2 open-label randomized controlled trial

A. Tam, C. Yip, Kwok-Hung Chan, 2022, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Cross-variant protection against SARS-CoV-2 infection in hamsters immunized with monovalent and bivalent inactivated vaccines

K. To, Cuiting Luo, J. Chan, 2022, International journal of biological sciences.

Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial

Kwok-Hung Chan, Raymond Liu, O. Tsang, 2020, The Lancet.

A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo

Dafydd G. Thomas, K. To, Jian-Piao Cai, 2021, Cell Reports Medicine.

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

Jian-Piao Cai, Cuiting Luo, J. Chan, 2021, Nature Communications.

Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Pharmaceuticals.

First Report of Human Infection by Agromyces mediolanus, a Gram-Positive Organism Found in Soil

P. Woo, C. Yip, J. Chan, 2015, Journal of Clinical Microbiology.

A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge

K. To, J. Chan, Honglin Chen, 2022, Nature Communications.

Response to “Novel Middle East respiratory syndrome coronavirus”

J. Chan, S. Lau, Patrick C Y Woo, 2013, Journal of the Formosan Medical Association.

Coronaviruses exploit a host cysteine-aspartic protease for replication

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Nature.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections by intranasal or testicular inoculation induces testicular damage preventable by vaccination in golden Syrian hamsters

K. To, D. Lung, C. Yip, 2022, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Severity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections

J. Chan, Y. Lau, M. Peiris, 2022, Emerging microbes & infections.

Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2

J. Chan, K. Yuen, H. Chu, 2022, Emerging microbes & infections.

A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern

J. Chan, K. Yuen, Jie Zhou, 2022, Viruses.

A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant

J. Chan, K. Yuen, Jie Zhou, 2022, Cell Research.

SARS-CoV-2 infects human neural progenitor cells and brain organoids

J. Chan, I. Hung, K. Yuen, 2020, Cell Research.

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

Lu Lu, Shibo Jiang, Yun Zhu, 2014, Nature Communications.

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

J. Chan, K. Yuen, H. Chu, 2019, Viruses.

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

Dong Yang, K. To, Jian-Piao Cai, 2020, Nature Communications.

A lethal mouse model using a mouse-adapted SARS-CoV-2 strain with enhanced binding to mouse ACE2 as an important platform for COVID-19 research

J. Chan, H. Chu, Hin Chu, 2021, EBioMedicine.

Low dose inocula of SARS-CoV-2 B.1.1.7 variant initiate more robust infections in the upper respiratory tract of hamsters than earlier D614G variants

K. To, Kwok-Hung Chan, J. Chan, 2021, bioRxiv.

Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology.

N. Ampel, J. Chan, T. Hohl, 2021, The Lancet. Infectious diseases.

Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids

J. Chan, H. Chu, D. Pei, 2022, Signal Transduction and Targeted Therapy.

Gordonia Species as Emerging Causes of Continuous-Ambulatory-Peritoneal-Dialysis-Related Peritonitis Identified by 16S rRNA and secA1 Gene Sequencing and Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS)

W. Leung, J. Chan, C. Tse, 2014, Journal of Clinical Microbiology.

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

Dong Yang, Lei Wen, Cun Li, 2019, Nature Communications.

Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

Susanna K. P. Lau, Patrick C. Y. Woo, P. Woo, 2015, Clinical Microbiology Reviews.

Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study

J. Chan, S. Lau, Chi-Ching Tsang, 2015, Journal of Clinical Microbiology.

Animal models for COVID-19

Lisa E. Gralinski, J. Chan, J. Segalés, 2020, Nature.

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Liyuan Liu, Yicheng Guo, K. To, 2021, Nature.

Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses

J. Chan, Zhiwei Chen, K. Yuen, 2021, bioRxiv.

Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters

J. Chan, K. Yuen, Hongzhe Sun, 2020, Nature Microbiology.

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

K. To, A. Tam, V. Cheng, 2021, Emerging microbes & infections.

The Coronavirus Disease 2019 pandemic: how does it spread and how do we stop it?

J. Chan, Xin Li, S. Sridhar, 2020, Current opinion in HIV and AIDS.

Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system

Jian-Piao Cai, Lin-Lei Chen, J. Chan, 2020, Pharmacological Research.

Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein

K. To, Jian-Piao Cai, J. Chan, 2020, mBio.

Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay

K. To, Jian-Piao Cai, Lin-Lei Chen, 2020, International journal of molecular sciences.

Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study

K. To, Jian-Piao Cai, Lin-Lei Chen, 2020, The Lancet Microbe.

Viral load in patients infected with pandemic H1N1 2009 influenza A virus

J. Peiris, K. To, Kwok-Hung Chan, 2009, Journal of medical virology.

Diversity of phenotypically non-dermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing

J. Chan, Xin Li, S. Lau, 2019, Emerging microbes & infections.

Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing

P. Woo, J. Chan, S. Lau, 2020, Emerging microbes & infections.

A global call for talaromycosis to be recognised as a neglected tropical disease.

J. Chan, K. Yuen, J. Perfect, 2021, The Lancet. Global health.

Use of Nasopharyngeal Aspirate for Diagnosis of Pneumocystis Pneumonia

K. To, Kwok-Hung Chan, R. W. Poon, 2013, Journal of Clinical Microbiology.

Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China

P. Woo, Jian-Piao Cai, J. Chan, 2019, Viruses.

Yeast identification by sequencing, biochemical kits, MALDI–TOF MS and rep-PCR DNA fingerprinting

P. Woo, J. Chan, P. Woo, 2018, Medical mycology.

Management of an incident of failed sterilization of surgical instruments in a dental clinic in Hong Kong.

V. Cheng, J. Chan, K. Yuen, 2013, Journal of the Formosan Medical Association = Taiwan yi zhi.

Genotyping of Enterocytozoon bieneusi among captive long-tailed macaques (Macaca fascicularis) in Hainan Province: high genetic diversity and zoonotic potential.

J. Chan, Meicen Liu, F. Yin, 2019, Acta tropica.

A Novel Psittacine Adenovirus Identified During an Outbreak of Avian Chlamydiosis and Human Psittacosis: Zoonosis Associated with Virus-Bacterium Coinfection in Birds

K. To, W. Chan, Kwok-Hung Chan, 2014, PLoS neglected tropical diseases.

Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong

O. Tsang, C. Yip, V. Cheng, 2020, Infection Control & Hospital Epidemiology.

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

K. To, J. Chan, Honglin Chen, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Adult-onset immunodeficiency due to anti-interferon-gamma autoantibody in mainland Chinese.

V. Cheng, J. Chan, I. Hung, 2014, Chinese medical journal.

Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry for identification of clinically significant bacteria that are difficult to identify in clinical laboratories

J. Chan, K. Yuen, S. Lau, 2013, Journal of Clinical Pathology.

Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

Ronald A. Li, S. Chanda, R. Sun, 2021, Nature.

Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

Wenjun Song, Qiang Fang, Haibo Wu, 2013, The Lancet.

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study

O. Tsang, K. To, D. Lung, 2020, The Lancet Microbe.

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

K. To, Jian-Piao Cai, J. Chan, 2020, Viruses.

A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals

Peter G. Schultz, Ren Sun, Sebastian Burgstaller-Muehlbacher, 2020, bioRxiv.

Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens

Kwok-Hung Chan, Chi-Chun Ho, S. Tsui, 2020, International journal of molecular sciences.

Viral Infections, an Overview with a Focus on Prevention of Transmission

V. Cheng, J. Chan, I. Hung, 2016, International Encyclopedia of Public Health.

Structure‐based discovery of clinically approved drugs as Zika virus NS2B‐NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo

Zheng Zhu, Horacio Pérez‐Sánchez, C. Yip, 2017, Antiviral research.

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection

Jian-Piao Cai, J. Chan, K. Yuen, 2021, Emerging microbes & infections.

Multimodal investigation of rat hepatitis E virus antigenicity: implications for infection, diagnostics, and vaccine efficacy.

C. Yip, Jian-Piao Cai, W. Chan, 2021, Journal of hepatology.

Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus

C. Yip, Kwok-Hung Chan, V. Cheng, 2018, Virology Journal.

Infection of bat and human intestinal organoids by SARS-CoV-2

K. To, C. Yip, Jian-Piao Cai, 2020, Nature Medicine.

A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters

K. To, Jian-Piao Cai, J. Chan, 2021, Emerging microbes & infections.

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

S. Chanda, E. Ruppin, J. Chan, 2020, Nature.

Discovery of SARS-CoV-2 Antivirals through Large-scale Drug Repositioning

Eytan Ruppin, Andrew I Su, Ren Sun, 2020, Nature.

Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

Chuan Qin, Yanfeng Yao, Cun Li, 2015, The Journal of infectious diseases.

Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination

Samson S. Y. Wong, P. Woo, Jian-Piao Cai, 2015, Journal of Virology.

Interspecies transmission and emergence of novel viruses: lessons from bats and birds

Herman Tse, Dong-Yan Jin, K. To, 2013, Trends in Microbiology.

Human airway organoids model SARS-CoV-2 high infectiousness and evasion of interferon response

C. Yip, Jian-Piao Cai, J. Chan, 2020 .

Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system

K. To, Jian-Piao Cai, Kwok-Hung Chan, 2021, Cell.

Emerging SARS-CoV-2 variants expand species tropism to murines

K. To, Jian-Piao Cai, W. Chan, 2021, EBioMedicine.

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

K. To, Jian-Piao Cai, J. Chan, 2021, EMBO molecular medicine.

Differentiated human airway organoids to assess infectivity of emerging influenza virus

K. To, J. Chan, Honglin Chen, 2018, Proceedings of the National Academy of Sciences.

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

Dong Yang, Yuxin Hou, Yue Chai, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Antibody evasion properties of SARS-CoV-2 Omicron sublineages

Liyuan Liu, J. Chan, K. Yuen, 2022, Nature.

Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China

C. Yip, V. Cheng, J. Chan, 2018, Emerging infectious diseases.

Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

Samson S. Y. Wong, K. To, Kwok-Hung Chan, 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Fatal pancytopenia due to albendazole treatment for strongyloidiasis

J. Chan, K. Yuen, W. Seto, 2018, IDCases.

hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs

Jian-Piao Cai, J. Chan, K. Yuen, 2022, Emerging microbes & infections.

Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests

Herman Tse, Kwok-Hung Chan, K. To, 2013, Journal of Infection.

SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamsters

K. To, Kwok-Hung Chan, J. Chan, 2020, bioRxiv.

Infection of immunocompromised patients by avian H9N2 influenza A virus.

Kwok-Hung Chan, V. Cheng, J. Chan, 2011, The Journal of infection.

Identification of a Novel Ichthyic Parvovirus in Marine Species in Hainan Island, China

J. Chan, K. Yuen, Jiang-feng Du, 2019, Front. Microbiol..

The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2

K. To, V. Cheng, J. Chan, 2020, Journal of Infection.

Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding

P. Woo, Jian-Piao Cai, J. Chan, 2018, The Journal of infectious diseases.

Coronaviruses: emerging and re-emerging pathogens in humans and animals

J. Chan, S. Lau, 2015, Virology Journal.

Early-Morning vs Spot Posterior Oropharyngeal Saliva for Diagnosis of SARS-CoV-2 Infection: Implication of Timing of Specimen Collection for Community-Wide Screening

K. To, C. Yip, V. Cheng, 2020, Open forum infectious diseases.

Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets

J. Chan, K. Yuen, H. Chu, 2021, Computational and structural biotechnology journal.

In Silico Structure-Based Design of Antiviral Peptides Targeting the Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein Gn

Jian-Piao Cai, Cuiting Luo, J. Chan, 2021, Viruses.

SARS-CoV-2 hijacks neutralizing dimeric IgA for enhanced nasal infection and injury

D. Ho, K. To, J. Chan, 2021, bioRxiv.

SARS-CoV-2 hijacks neutralizing dimeric IgA for enhanced nasal infection

Man, Yeung, Zhang, 2021 .

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

Jian-Piao Cai, J. Chan, Honglin Chen, 2015, The Journal of infectious diseases.

Ebola virus disease: a highly fatal infectious disease reemerging in West Africa

V. Cheng, J. Chan, K. Yuen, 2014, Microbes and Infection.

Emergence in China of human disease due to avian influenza A(H10N8)--cause for concern?

V. Cheng, J. Chan, Honglin Chen, 2014, The Journal of infection.

Clinical management and infection control of SARS: Lessons learned

K. To, V. Cheng, J. Chan, 2013, Antiviral Research.

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

K. To, Kwok-Hung Chan, J. Chan, 2021, Nature Communications.

Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals

K. To, Cuiting Luo, J. Chan, 2022, Cellular & Molecular Immunology.

Animal models for COVID-19

Lisa E. Gralinski, J. Chan, J. Segalés, 2020, Nature.

Immunogenicity of intradermal trivalent influenza vaccine with topical imiquimod: a double blind randomized controlled trial.

K. To, Kwok-Hung Chan, V. Cheng, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Long SARS-CoV-2 nucleocapsid sequences in blood monocytes collected soon after hospital admission

Kwok-Hung Chan, Kaiming Tang, K. To, 2020, bioRxiv.

MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Chuan Qin, Yanfeng Yao, Kwok-Hung Chan, 2016, Nature Microbiology.

Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses.

J. Chan, K. Yuen, H. Tsoi, 2009, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the prepandemic phase in Hong Kong

K. To, V. Cheng, J. Chan, 2020, American Journal of Infection Control.

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses

Yicheng Guo, J. Chan, Zhiwei Chen, 2021, Emerging microbes & infections.

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses

Yicheng Guo, J. Chan, Zhiwei Chen, 2021, bioRxiv.

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility

K. To, Jian-Piao Cai, W. Chan, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

K. To, Kwok-Hung Chan, J. Chan, 2021, Communications Biology.

SARS coronavirus ORF 8 protein is acquired from SARS-related coronavirus 1 from greater horseshoe bats through recombination 2 3

Samson S. Y. Wong, Jian-Piao Cai, J. Chan, 2015 .

Nosocomial transmission of chickenpox and varicella zoster virus seroprevalence rate amongst healthcare workers in a teaching hospital in China

S. Lo, J. Chan, K. Yuen, 2019, BMC Infectious Diseases.

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Liyuan Liu, Yicheng Guo, K. To, 2021, Nature.

Infection of bat and human intestinal organoids by SARS-CoV-2

O. Tsang, K. To, C. Yip, 2020, Nature Medicine.

Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity

Jian-Piao Cai, J. Chan, K. Yuen, 2021, EBioMedicine.

Efficacy of Clarithromycin‐Naproxen‐Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open‐label Randomized, Controlled, Phase IIb/III Trial

A. Tam, Kwok-Hung Chan, V. Cheng, 2017, Chest.

Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19)

K. To, C. Yip, Kwok-Hung Chan, 2020, Infection Control & Hospital Epidemiology.

Cellular Sensors and Viral Countermeasures: A Molecular Arms Race between Host and SARS-CoV-2

J. Chan, Shuofeng Yuan, Haoran Sun, 2023, Viruses.

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists

K. To, Jian-Piao Cai, J. Chan, 2020, Emerging microbes & infections.

Clinical Evaluation of the New High-Throughput Luminex NxTAG Respiratory Pathogen Panel Assay for Multiplex Respiratory Pathogen Detection

V. Cheng, J. Chan, K. Yuen, 2016, Journal of Clinical Microbiology.

Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus.

K. To, J. Chan, Honglin Chen, 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Animal models in SARS-CoV-2 research

J. Chan, K. Yuen, H. Chu, 2022, Nature Methods.

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons

C. Yip, Jian-Piao Cai, Kwok-Hung Chan, 2016, EBioMedicine.

Mice A ( H 1 N 1 ) pdm 09 Virus Infection in BALB / c Responses against Influenza Expedites and Augments Humoral Immune Combination with Influenza Vaccine Toll-Like Receptor 7 Agonist Imiquimod in

K. To, J. Chan, K. Yuen, 2014 .

Donor-Derived Genotype 4 Hepatitis E Virus Infection, Hong Kong, China, 2018

P. Woo, C. Yip, Jian-Piao Cai, 2019, Emerging infectious diseases.

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

J. Chan, Zhiwei Chen, K. Yuen, 2021, Nature Communications.

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

J. Chan, Zhiwei Chen, K. Yuen, 2022, Science Translational Medicine.

Middle East Respiratory Syndrome Interpreted: Human Herpesvirus 6B Pneumonia

P. Woo, C. Yip, Kwok-Hung Chan, 2016, The American Journal of Medicine.

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

K. To, Kwok-Hung Chan, J. Chan, 2020, Emerging microbes & infections.

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

J. Sodroski, J. Chan, K. Yuen, 2020, Nature.

High Titer and Avidity of Nonneutralizing Antibodies against Influenza Vaccine Antigen Are Associated with Severe Influenza

K. To, Kwok-Hung Chan, J. Chan, 2012, Clinical and Vaccine Immunology.

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication

K. To, Cuiting Luo, J. Chan, 2021, Cell Discovery.

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication

K. To, Jian-Piao Cai, Cuiting Luo, 2021, Cell discovery.

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

K. To, Jian-Piao Cai, J. Chan, 2020, Science Advances.

Recent developments in mycobacterial research.

J. Chan, V. Mehra, A. J. Steyn, 1999, Current opinion in infectious diseases.

Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model

K. To, J. Chan, K. Yuen, 2022, Emerging microbes & infections.

Differences in Antibody Responses of Individuals with Natural Infection and Those Vaccinated against Pandemic H1N1 2009 Influenza

K. To, Kwok-Hung Chan, V. Cheng, 2011, Clinical and Vaccine Immunology.

D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice

Ke Zhang, Bojian Zheng, Kwok-Hung Chan, 2010, Experimental biology and medicine.

Effect of clinical and virological parameters on the level of neutralizing antibody against pandemic influenza A virus H1N1 2009.

K. To, Kwok-Hung Chan, V. Cheng, 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities

J. Chan, Honglin Chen, K. Yuen, 2013, The Lancet Infectious Diseases.

Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant

J. Chan, K. Yuen, Lu Lu, 2022, Cell Research.

Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection

O. Tsang, K. To, C. Yip, 2020, Journal of Clinical Virology.

High Incidence of Severe Influenza among Individuals over 50 Years of Age

K. To, Kwok-Hung Chan, J. Chan, 2011, Clinical and Vaccine Immunology.

Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits

K. To, C. Yip, W. Chan, 2020, Journal of Clinical Virology.

Comparative evaluation of a dual-target real-time RT-PCR assay for COVID-19 diagnosis and assessment of performance in pooled saliva and nasopharyngeal swab samples

K. To, Kwok-Hung Chan, A. C. Ng, 2021, Expert review of molecular diagnostics.

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies

D. Ho, K. To, J. Chan, 2021, Cell Host & Microbe.

Factors affecting stability and infectivity of SARS-CoV-2

K. To, Kwok-Hung Chan, V. Cheng, 2020, Journal of Hospital Infection.

Author Correction: SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Nature Communications.

Identification and characterization of GLDC as host susceptibility gene to severe influenza

K. To, J. Chan, K. Yuen, 2018, EMBO molecular medicine.

ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury

J. Chan, K. Yuen, M. Kiso, 2021, Nature Communications.

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells

C. Yip, J. Chan, K. Yuen, 2019, International journal of molecular sciences.

Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying blaKPC-2 in a Klebsiella pneumoniae

V. Cheng, J. Chan, P. Ho, 2013, Current Microbiology.

Inhaled Dry Powder Formulation of Tamibarotene, a Broad‐Spectrum Antiviral against Respiratory Viruses Including SARS‐CoV‐2 and Influenza Virus

J. Chan, K. Yuen, Shuofeng Yuan, 2021, Advanced Therapeutics.

Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer

Jian-Piao Cai, J. Chan, K. Yuen, 2020, Journal of Infection.

Liquid repellency enabled antipathogen coatings

J. Chan, Nan Huang, H. Chu, 2021, Materials Today Bio.

Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2

K. To, C. Yip, Kwok-Hung Chan, 2020, Emerging microbes & infections.

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis

J. Chan, K. Yuen, Jie Zhou, 2015, Virology Journal.

The role of laboratory diagnostics in emerging viral infections: the example of the Middle East respiratory syndrome epidemic

J. Chan, S. Lau, S. Sridhar, 2017, Journal of Microbiology.

Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

S. Chanda, R. Sun, K. To, 2020, Research square.

Subcutaneous phaeohyphomycosis in a patient with IgG4-related sclerosing disease caused by a novel ascomycete, Hongkongmyces pedis gen. et sp. nov.: first report of human infection associated with the family Lindgomycetaceae.

P. Woo, J. Chan, S. Lau, 2014, Medical mycology.

From SARS coronavirus to novel animal and human coronaviruses.

J. Chan, K. Yuen, K. To, 2013, Journal of thoracic disease.

Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms

K. To, A. Tam, C. Yip, 2020, Infection.

Title Fatal anti-aquaporin-4 seropositive neuromyelitis opticaspectrum disorder in tuberculosis

J. Chan, K. Yuen, S. Sridhar, 2014 .

Berbamine inhibits the infection of SARS-CoV-2 and flaviviruses by compromising TPRMLs-mediated endolysosomal trafficking of viral receptors

J. Chan, J. Yue, H. Chu, 2020 .

Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection

O. Tsang, K. To, C. Yip, 2020, International journal of molecular sciences.

K. To, Kwok-Hung Chan, J. Chan, 2016, Virology Journal.

A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamsters

K. To, Jian-Piao Cai, J. Chan, 2022, Cell Discovery.

Molecular prevalence and subtyping of Cryptosporidium hominis among captive long-tailed macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) from Hainan Island, southern China

J. Chan, Meicen Liu, F. Yin, 2019, Parasites & vectors.

Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

K. To, Kwok-Hung Chan, J. Chan, 2020, bioRxiv.

Control of hospital endemicity of multiple-drug-resistant Acinetobacter baumannii ST457 with directly observed hand hygiene

J. H. Chen, C. Yip, R. W. Poon, 2015, European Journal of Clinical Microbiology & Infectious Diseases.

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor

Jian-Piao Cai, Cuiting Luo, J. Chan, 2021, International journal of biological sciences.

ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury

J. Chan, K. Yuen, M. Kiso, 2020, Nature communications.

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy

C. Yip, J. Chan, K. Yuen, 2019, International journal of molecular sciences.

A new ASPECT for complicated urinary tract infections

J. Chan, K. Yuen, 2015, The Lancet.

Absence of Vaccine-enhanced Disease With Unexpected Positive Protection Against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Inactivated Vaccine Given Within 3 Days of Virus Challenge in Syrian Hamster Model

K. To, D. Lung, Jian-Piao Cai, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

C. Yip, Jian-Piao Cai, Kwok-Hung Chan, 2016, Emerging Microbes & Infections.

Comparative analysis of SARS‐CoV‐2 Omicron BA.2.12.1 and BA.5.2 variants

J. Chan, H. Chu, Shuofeng Yuan, 2022, Journal of medical virology.

Altered host protease determinants for SARS-CoV-2 Omicron

Jian-Piao Cai, J. Chan, K. Yuen, 2023, Science advances.

The role of laboratory diagnostics in emerging viral infections: the example of the Middle East respiratory syndrome epidemic

Susanna K. P. Lau, P. Woo, J. Chan, 2017, Journal of Microbiology.

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant

P. Woo, C. Yip, Jian-Piao Cai, 2018, Emerging infectious diseases.

Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy

J. Chan, K. Yuen, Z. Zuo, 2021, Chemical science.

Identification of a Novel Astrovirus in Pinnipeds

J. Chan, K. Yuen, Yun Zhang, 2022, Frontiers in Microbiology.

An elite broadly neutralizing antibody protects SARS-CoV-2 Omicron variant challenge

K. To, J. Chan, Zhiwei Chen, 2022, bioRxiv.

Use of fluoroquinolones is the single most important risk factor for the high bacterial load in patients with nasal and gastrointestinal colonization by multidrug-resistant Acinetobacter baumannii

V. Cheng, J. Chan, I. Hung, 2015, European Journal of Clinical Microbiology & Infectious Diseases.

Epidemiology of Klebsiella oxytoca-Associated Diarrhea Detected by Simmons Citrate Agar Supplemented with Inositol, Tryptophan, and Bile Salts

V. Cheng, J. Chan, I. Hung, 2012, Journal of Clinical Microbiology.

Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay

Samson S. Y. Wong, K. To, R. W. Poon, 2019, Journal of Clinical Pathology.