Christopher W. J. Smith

发表

Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay.

C. Gooding, M. Wollerton, E. Wagner, 2004, Molecular cell.

Alternative splicing: global insights

Christopher W. J. Smith, M. Hallegger, M. Llorian, 2010, The FEBS journal.

Understanding alternative splicing: towards a cellular code

F. Clark, Christopher W. J. Smith, A. Matlin, 2005, Nature Reviews Molecular Cell Biology.

Quantification of Alternative Splice Variants

Christopher W. J. Smith, M. Llorian, Miriam Llorian, 2012 .

Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

Nicholas J. McGlincy, Christopher W. J. Smith, N. McGlincy, 2008, Trends in biochemical sciences.

Polypyrimidine Tract Binding Protein Functions as a Repressor To Regulate Alternative Splicing of α-Actinin Mutally Exclusive Exons

C. Gooding, Christopher W. J. Smith, Justine Southby, 1999, Molecular and Cellular Biology.

Mutually exclusive splicing of α-tropomyosin exons enforced by an unusual lariat branch point location: Implications for constitutive splicing

Christopher W. J. Smith, B. Nadal-Ginard, Bernardo Nadal-Ginard, 1989, Cell.

Alternative Splice Site Selection

Christopher W. J. Smith, M. Coelho, Miguel B. Coelho, 2012 .

An Apparent Pseudo-Exon Acts both as an Alternative Exon That Leads to Nonsense-Mediated Decay and as a Zero-Length Exon

S. Grellscheid, Christopher W. J. Smith, Sushma-Nagaraja Grellscheid, 2006, Molecular and Cellular Biology.

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

J. G. Patton, Christopher W. J. Smith, B. Nadal-Ginard, 1989, Nature.

Alternative splicing as a source of phenotypic diversity

Christopher W. J. Smith, C. Jiggins, Charlotte J Wright, 2022, Nature Reviews Genetics.

Repression of alpha-actinin SM exon splicing by assisted binding of PTB to the polypyrimidine tract.

C. Gooding, Christopher W. J. Smith, A. Matlin, 2007, RNA.

Phosphorylation of the smooth muscle master splicing regulator RBPMS regulates its splicing activity

Michael D. Barnhart, C. Gooding, Christopher W. J. Smith, 2022, bioRxiv.

Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors

Christopher W. J. Smith, O. Hansson, K. Stenkula, 2022, Cellular and Molecular Life Sciences.

Detection of a Novel ATP-Dependent Cross-Linked Protein at the 5′ Splice Site-U1 Small Nuclear RNA Duplex by Methylene Blue-Mediated Photo-Cross-Linking

Christopher W. J. Smith, Zhi-Ren Liu, B. Sargueil, 1998, Molecular and Cellular Biology.

Photo-Cross-Linking Methylene Blue-Mediated Site-U 1 Small Nuclear RNA Duplex by Splice ′ Cross-Linked Protein at the 5 Detection of a Novel ATP-Dependent

Christopher W. J. Smith, Zhi-Ren Liu, B. Sargueil, 1998 .

Alternative splicing: combinatorial output from the genome.

G. C. Roberts, Christopher W. J. Smith, Christopher W J Smith, 2002, Current opinion in chemical biology.

Alternative Pre‐mRNA Splicing: Prevalence, Mechanisms, and Disease

J. G. Patton, Christopher W. J. Smith, 2002 .

Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1.

Christopher W. J. Smith, H. Field, S. Biswas, 2007, The Journal of antimicrobial chemotherapy.

RNAi is antagonized by A→I hyper‐editing

Christopher W. J. Smith, A D Scadden, C W Smith, 2001, EMBO reports.

A nonsense exon in the Tpm1 gene is silenced by hnRNP H and F.

Christopher W. J. Smith, M. Hallegger, Joel Coles, 2008, RNA.

Regulation of alternative pre-mRNA splicing.

Christopher W. J. Smith, Miguel B. Coelho, 2014, Methods in molecular biology.

The PTB interacting protein raver1 regulates α‐tropomyosin alternative splicing

C. Gooding, Christopher W. J. Smith, R. Singer, 2003 .

A Novel Polypyrimidine Tract-binding Protein Paralog Expressed in Smooth Muscle Cells*

C. Gooding, Christopher W. J. Smith, P. Kemp, 2003, The Journal of Biological Chemistry.

Novel modes of splicing repression by PTB.

Christopher W. J. Smith, R. Spellman, Rachel Spellman, 2006, Trends in biochemical sciences.

Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein.

T. Cooper, Christopher W. J. Smith, A. Matlin, 2003, RNA.

Genome-Wide Association between Branch Point Properties and Alternative Splicing

Christopher W. J. Smith, Eduardo Eyras, André Corvelo, 2010, PLoS Comput. Biol..

Matrin3: connecting gene expression with the nuclear matrix

J. Ule, Christopher W. J. Smith, J. Attig, 2016, Wiley interdisciplinary reviews. RNA.

Four exons of the serotonin receptor 4 gene are associated with multiple distant branch points.

Christopher W. J. Smith, M. Hallegger, Andrew Sobala, 2010, RNA.

Polypyrimidine tract binding protein regulates alternative splicing of an aberrant pseudoexon in NF1

D. Baralle, Christopher W. J. Smith, M. Llorian, 2008, The FEBS journal.

Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content

Christopher W. J. Smith, R. Jackson, F. Robinson, 2008, PloS one.

A splicing silencer that regulates smooth muscle specific alternative splicing is active in multiple cell types.

Christopher W. J. Smith, N. Gromak, 2002, Nucleic acids research.

Decoding muscle alternative splicing.

Christopher W. J. Smith, M. Llorian, Miriam Llorian, 2011, Current opinion in genetics & development.

Tropomyosin exons as models for alternative splicing.

C. Gooding, Christopher W. J. Smith, Clare Gooding, 2008, Advances in experimental medicine and biology.

The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing.

C. Gooding, Christopher W. J. Smith, R. Singer, 2003, The EMBO journal.

Repression of α-actinin SM exon splicing by assisted binding of PTB to the polypyrimidine tract

C. Gooding, Christopher W. J. Smith, A. Matlin, 2007 .

Lamin A/C controls nuclear matrin-3 levels and localization, but not alternative splicing of cassette exons

C. Gooding, Christopher W. J. Smith, R. Hayward, 2018, bioRxiv.

Alternative Splicing: Cell‐type‐specific and Developmental Control

J. Valcárcel, Christopher W. J. Smith, 2006 .

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain

Stefan Hüttelmaier, Robert H Singer, Mike Lorenz, 2006, Nature Structural &Molecular Biology.

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

Christopher W. J. Smith, M. Llorian, E. Olson, 2013, Journal of Cell Science.

Defining the roles and interactions of PTB.

Richard J Jackson, C. Gooding, Christopher W. J. Smith, 2012, Biochemical Society transactions.

Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses

Clive R. Bagshaw, C. Gooding, Christopher W. J. Smith, 2010, The EMBO journal.

Visualization of alternative splicing in vivo.

Christopher W. J. Smith, P. Kemp, P. D. Ellis, 2005, Methods.

Alternative Splicing— When Two’s a Crowd

Christopher W. J. Smith, 2005, Cell.

A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties

C. Gooding, Christopher W. J. Smith, S. Harper, 2021, Oncogenesis.

Alternative pre-mRNA splicing: the logic of combinatorial control.

J. Valcárcel, Christopher W. J. Smith, C. W. Smith, 2000, Trends in biochemical sciences.

Co-transcriptional commitment to alternative splice site selection.

G. C. Roberts, C. Gooding, Christopher W. J. Smith, 1998, Nucleic acids research.

Scanning and competition between AGs are involved in 3' splice site selection in mammalian introns

Christopher W. J. Smith, C. W. Smith, B. Nadal-Ginard, 1993, Molecular and cellular biology.

Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated alpha-tropomyosin exon.

G. C. Roberts, C. Gooding, Christopher W. J. Smith, 1969, RNA.

Smooth muscle‐specific switching of alpha‐tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon.

G. C. Roberts, C. Gooding, Christopher W. J. Smith, 1994, The EMBO journal.

Cell-type specific regulator RBPMS switches alternative splicing via higher-order oligomerization and heterotypic interactions with other splicing regulators

C. Gooding, Christopher W. J. Smith, M. Peacey, 2023, Nucleic acids research.

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

J. Marioni, I. Macaulay, M. Surani, 2018, Cell Discovery.

Regulation of alternative splicing by PTB and associated factors.

Nicholas J. McGlincy, C. Gooding, M. Wollerton, 2005, Biochemical Society transactions.

Detection of a Novel ATP-Dependent Cross-Linked Protein at the 5′ Splice Site-U1 Small Nuclear RNA Duplex by Methylene Blue-Mediated Photo-Cross-Linking

Christopher W. J. Smith, Zhi-Ren Liu, B. Sargueil, 1998, Molecular and Cellular Biology.

Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

Nicholas J. McGlincy, Christopher W. J. Smith, 2008, Trends in biochemical sciences.