D. Laukens

D. Laukens, W. van Biesen, R. Vanholder, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn’s disease/infectious colitis and healthy controls

D. Laukens, M. De Vos, P. Hindryckx, 2013, Journal of Inflammation.

Intrarectal Nitric Oxide Administration Prevents Cellular Infiltration but Not Colonic Injury During Dextran Sodium Sulfate Colitis

T. Wiele, D. Laukens, M. Vos, 2012, Digestive Diseases and Sciences.

Inverse correlation between metallothioneins and hypoxia-inducible factor 1 alpha in colonocytes and experimental colitis.

D. Laukens, M. De Vos, P. Hindryckx, 2011, Biochemical and biophysical research communications.

CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn’s disease

D. Laukens, M. De Vos, E. Remaut, 2004, Annals of the rheumatic diseases.

Longitudinal quantification of inflammation in the murine dextran sodium sulfate‐induced colitis model using &mgr;PET/CT1

D. Laukens, M. De Vos, L. Delrue, 2011, Inflammatory bowel diseases.

Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension.

P. Carmeliet, D. Laukens, A. Geerts, 2009, Gastroenterology.

The paradox of the unfolded protein response in cancer.

D. Laukens, F. Heindryckx, A. Geerts, 2013, Anticancer research.

Genetics of spondyloarthropathies and inflammatory bowel disease: searching for common susceptibility factors

D. Laukens, M. Vos, 2008 .

Intestinal Barrier Dysfunction: The Primary Driver of IBD?

D. Laukens, P. Hindryckx, 2012 .

High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Hailiang Huang, Stephan Ripke, Andre Franke, 2014, Nature Genetics.

Materials for : Host-microbe interactions shape genetic risk for inflammatory bowel disease

Judy H. Cho, C. Gieger, M. Daly, 2012 .

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Judy H. Cho, John P. Ferguson, G. Wainrib, 2019, Scientific Reports.

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

Isabelle Cleynen, Michel Georges, Paul Rutgeerts, 2011, Nature Genetics.

Role of metallothioneins as danger signals in the pathogenesis of colitis

C. Vanhove, D. Laukens, M. Vos, 2014, The Journal of pathology.

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

D. Laukens, A. Geerts, C. Van Steenkiste, 2016, Oncotarget.

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

B. Lambrecht, C. Vanhove, D. Laukens, 2014, Hepatology International.

Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease

Y. Moreau, J. Vermeesch, C. Robberecht, 2016, Inflammatory bowel diseases.

Unmet Needs in IBD: the Case of Fatigue

D. Laukens, S. Danese, P. Hindryckx, 2018, Clinical Reviews in Allergy & Immunology.

Metabolic modulation during intestinal fibrosis

D. Laukens, Simon Bos, 2020, Journal of digestive diseases.

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

C. Vanhove, D. Laukens, A. Geerts, 2015, Oncotarget.

Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen‐induced liver injury

D. Laukens, A. Geerts, H. Van Vlierberghe, 2021, Journal of leukocyte biology.

A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach.

D. Laukens, M. Marzorati, P. van den Abbeele, 2013, Journal of agricultural and food chemistry.

Interindividual differences in response to treatment with butyrate-producing Butyricicoccus pullicaecorum 25-3T studied in an in vitro gut model.

J. Raes, G. Falony, D. Laukens, 2015, FEMS microbiology ecology.

Evidence for a Potential Role of Metallothioneins in Inflammatory Bowel Diseases

D. Laukens, M. De Vos, A. Waeytens, 2009, Mediators of inflammation.

Versatile human in vitro triple coculture model coincubated with adhered gut microbes reproducibly mimics pro‐inflammatory host‐microbe interactions in the colon

D. Laukens, A. Rajković, T. van de Wiele, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Novel development in extraintestinal manifestations and spondylarthropathy.

D. Laukens, M. De Vos, P. Hindryckx, 2011, Best practice & research. Clinical gastroenterology.

Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

D. Laukens, S. Coulon, A. Geerts, 2014, Liver international : official journal of the International Association for the Study of the Liver.

Altered gut transcriptome in spondyloarthropathy

D. Laukens, M. De Vos, P. Hummelen, 2006, Annals of the rheumatic diseases.

CARD 15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn ’ s disease

D. Laukens, E. Remaut, D. Elewaut, 2004 .

Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn’s disease

D. Laukens, M. Vos, E. Remaut, 2004, Annals of the rheumatic diseases.

Inflammation-independent mechanisms of intestinal fibrosis : the role of the extracellular matrix

D. Laukens, 2018 .

Albumin-dependent and independent mechanisms in the syndrome of kwashiorkor

D. Laukens, G. Gonzales, J. Berkley, 2021, medRxiv.

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

D. Laukens, M. De Vos, P. van den Abbeele, 2016, Environmental microbiology.

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

P. Carmeliet, D. Laukens, A. Geerts, 2016, BMC Cancer.

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential

D. Laukens, K. Sheahan, A. O'Grady, 2015, Clinical and experimental immunology.

Detection and Manipulation of the Stress Response Protein Metallothionein

D. Laukens, L. Devisscher, M. Lynes, 2017, Current protocols in toxicology.

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

P. Vandenabeele, D. Laukens, M. Vos, 2014, Laboratory Investigation.

Pharmacologic activation of tumor hypoxia: a means to increase tumor 2-deoxy-2-[18F]fluoro-D-glucose uptake?

Debby Laukens, Christophe Van de Wiele, D. Laukens, 2013, Molecular imaging.

Assessment of faecal microbial transfer in irritable bowel syndrome with severe bloating

J. Raes, D. Laukens, H. Van Vlierberghe, 2016, Gut.

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

B. Lambrecht, C. Vanhove, D. Laukens, 2014, European journal of gastroenterology & hepatology.

Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn’s Like Ileitis

D. Laukens, M. De Vos, P. Hindryckx, 2021, Biology.

Hydroxylase Inhibition Abrogates TNF-α–Induced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1–Dependent Repression of FADD

P. Vandenabeele, D. Laukens, M. De Vos, 2010, The Journal of Immunology.

Metallothionein and stress combine to affect multiple organ systems

D. Laukens, D. Lawrence, J. Hidalgo, 2014, Cell Stress and Chaperones.

Role of integrin expression in the prediction of response to vedolizumab: A prospective real‐life multicentre cohort study

D. Laukens, M. De Vos, S. Tavernier, 2022, Clinical and translational medicine.

Prevalence of Fatigue and Unrecognized Depression in Patients with Inflammatory Bowel Disease in Remission under Immunosuppressants and Biologicals

D. Laukens, M. De Vos, G. Gonzales, 2021, Journal of clinical medicine.

Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease

D. Laukens, J. Vandesompele, M. De Vos, 2010, BMC Immunology.

MRI texture analysis of T2-weighted images is preferred over magnetization transfer imaging for readily longitudinal quantification of gut fibrosis

D. Laukens, M. De Vos, L. Delrue, 2023, European Radiology.

Human metallothionein expression under normal and pathological conditions: mechanisms of gene regulation based on in silico promoter analysis.

D. Laukens, M. De Vos, P. de Bleser, 2009, Critical reviews in eukaryotic gene expression.

Validated High Resolution Mass Spectrometry-Based Approach for Metabolomic Fingerprinting of the Human Gut Phenotype.

Lynn Vanhaecke, Massimo Marzorati, Debby Laukens, 2015, Analytical chemistry.

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

D. Laukens, M. De Vos, T. van de Wiele, 2017, Scientific Reports.

Tumor PD-L1 status and CD8+ tumor-infiltrating T cells: markers of improved prognosis in oropharyngeal cancer.

D. Laukens, S. Rottey, S. Aspeslagh, 2017, Oncotarget.

A novel susceptibility locus for Crohn's disease identified by whole genome association maps to a gene desert on chromosome 5p13.1 and modulates the level of expression of the prostaglandin receptor EP4

L. Liang, S. Heath, S. Hansoul, 2005 .

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Judy H. Cho, C. Gieger, H. Hakonarson, 2015 .

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Lisa, Husam, John P. Ferguson, 2023 .

Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis

C. Libioulle, C. Sandor, D. Laukens, 2009, PloS one.

Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn’s disease/infectious colitis and healthy controls

D. Laukens, M. De Vos, P. Hindryckx, 2013, Journal of Inflammation.

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor.

D. Laukens, T. Holvoet, D. Leysen, 2017, Gastroenterology.

Ursodeoxycholic Acid and Its Taurine- or Glycine-Conjugated Species Reduce Colitogenic Dysbiosis and Equally Suppress Experimental Colitis in Mice

D. Laukens, T. Holvoet, M. De Vos, 2017, Applied and Environmental Microbiology.

Cellular diversity in the colon: another brick in the wall

D. Laukens, I. Cleynen, 2019, Nature Reviews Gastroenterology & Hepatology.

Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia

D. Laukens, M. Vos, P. Hindryckx, 2011 .

A comprehensive metabolite fingerprint of fibrostenosis in patients with Crohn’s disease

D. Laukens, Ellen De Paepe, Vera Plekhova, 2023, Scientific reports.

Subclinical gut inflammation in spondyloarthritis is associated with a pro-angiogenic intestinal mucosal phenotype

D. Laukens, D. Elewaut, C. Cuvelier, 2011, Annals of the rheumatic diseases.

Effect of 5-hydroxytryptophan on fatigue in quiescent inflammatory bowel disease: a randomized controlled trial.

O. Dewit, D. Laukens, S. Vermeire, 2022, Gastroenterology.

Safety and efficacy of faecal microbiota transplantation in patients with mild to moderate Parkinson's disease (GUT-PARFECT): a double-blind, placebo-controlled, randomised, phase 2 trial.

D. Laukens, R. Vandenbroucke, P. Santens, 2024, EClinicalMedicine.