H. Pijl

发表

Bromocriptine: a novel approach to the treatment of type 2 diabetes.

J. Lancaster, H. Pijl, S. Ohashi, 2000, Diabetes care.

Impact of Meal Timing and Frequency on the Twenty-Four-Hour Leptin Rhythm

H. Pijl, A. Fogteloo, F. Roelfsema, 2004, Hormone Research in Paediatrics.

Weight loss in neurodegenerative disorders

B. Bloem, H. Pijl, R. Roos, 2008, Journal of Neurology.

Selenium supplementation for Hashimoto's thyroiditis.

Z. Fedorowicz, H. Pijl, E. V. van Zuuren, 2013, The Cochrane database of systematic reviews.

UvA-DARE ( Digital Academic Repository ) Dynamic metabolomic data analysis : a tutorial

A. Smilde, H. Hoefsloot, H. Pijl, 2010 .

Effects of olanzapine and haloperidol on the metabolic status of healthy men.

H. Pijl, J. Romijn, F. Roelfsema, 2010, The Journal of clinical endocrinology and metabolism.

Hyposomatotropism blunts lipolysis in abdominally obese women.

H. Pijl, J. Romijn, H. Sauerwein, 2002, The Journal of clinical endocrinology and metabolism.

Influence of obesity and body fat distribution on growth hormone kinetics in humans.

H. Pijl, C. Roelen, M. Frölich, 1999, American journal of physiology. Endocrinology and metabolism.

Influence of obesity and body fat distribution on growth hormone kinetics in humans.

H. Pijl, C. Roelen, M. Frölich, 1999, The American journal of physiology.

The Gut-Brain Axis

H. Pijl, N. Hattori, J. Romijn, 2021, Annals of Nutrition and Metabolism.

Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis.

Z. Fedorowicz, H. Pijl, E. Manheimer, 2015, The American journal of clinical nutrition.

Growth hormone and ghrelin secretion in Huntington’s disease

H. Pijl, R. Roos, N. Aziz, 2010 .

Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS.

H. Pijl, J. Veldhuis, F. Roelfsema, 2002, American journal of physiology. Endocrinology and metabolism.

Estimation of growth hormone secretion rate: impact of kinetic assumptions intrinsic to the analytical approach.

H. Pijl, J. Veldhuis, A. Meinders, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans

H. Pijl, H. Lamb, J. Smit, 2014, Diabetologia.

Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01)

H. Putter, H. Pijl, M. Pepels, 2019, Breast Cancer Research.

Diminished adrenal sensitivity and ACTH efficacy in obese premenopausal women.

D. M. Keenan, D. Keenan, H. Pijl, 2012, European journal of endocrinology.

The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system

H. Pijl, J. Romijn, D. Ouwens, 2013, British journal of pharmacology.

Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH

H. Pijl, R. Westendorp, D. van Heemst, 2021, Aging.

Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

H. Pijl, R. Westendorp, D. van Heemst, 2020, Journal of the Endocrine Society.

Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice[S]

H. Pijl, J. Romijn, L. Havekes, 2011, Journal of Lipid Research.

Ambulant 24‐h glucose rhythms mark calendar and biological age in apparently healthy individuals

H. Pijl, P. Slagboom, R. Westendorp, 2013, Aging cell.

Delayed onset of the diurnal melatonin rise in patients with Huntington’s disease

H. Pijl, R. Roos, N. Aziz, 2009, Journal of Neurology.

Effect of a 2-day very low-energy diet on skeletal muscle insulin sensitivity in obese type 2 diabetic patients on insulin therapy.

H. Pijl, D. Ouwens, A. Meinders, 2005, Metabolism: clinical and experimental.

Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin.

H. Pijl, J. Romijn, M. Frölich, 2005, Metabolism: clinical and experimental.

Glucose homeostasis in abdominal obesity: hepatic hyperresponsiveness to growth hormone action.

H. Pijl, M. D. de Kam, M. Frölich, 2004, American journal of physiology. Endocrinology and metabolism.

Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study.

H. Pijl, A. Kalsbeek, S. Overeem, 2014, Sleep.

Short-term topiramate treatment does not improve insulin sensitivity or secretion in obese insulin-resistant women.

H. Pijl, I. Jazet, Trea C. M. Streefland, 2012, European journal of endocrinology.

Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin-dependent diabetes.

H. Pijl, M. Frölich, A. Meinders, 1994, Metabolism: clinical and experimental.

Dietary fat content alters insulin-mediated glucose metabolism in healthy men.

H. Pijl, J. Romijn, A. Meijer, 2001, The American journal of clinical nutrition.

Plasma amino acid ratios related to brain serotonin synthesis in response to food intake in bulimia nervosa

H. Pijl, R. Verkes, M. Frölich, 1995, Biological Psychiatry.

Effect of flavor on neuronal responses of the hypothalamus and ventral tegmental area

S. Rombouts, H. Pijl, M. Hoeksma, 2019, Scientific Reports.

Bodyweight Change as an Adverse Effect of Drug Treatment

H. Pijl, A. Meinders, 1996, Drug safety.

Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

H. Pijl, P. Slagboom, R. Westendorp, 2016, Experimental Gerontology.

Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone

H. Pijl, R. Westendorp, D. van Heemst, 2020, The Journal of clinical endocrinology and metabolism.

Evidence for brain serotonin-mediated control of carbohydrate consumption in normal weight and obese humans.

H. Pijl, M. Frölich, A. Meinders, 1993, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Functional and Metabolic Imaging of the Cardiovascular System in Young Healthy South Asians and Caucasians Unveils Early Differences

H. Pijl, H. Lamb, A. de Roos, 2013, Diabetes Care.

Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin.

H. Pijl, J. Romijn, R. Buijs, 2004, Diabetes.

Calorie restriction and Roux‐en‐Y gastric bypass have opposing effects on circulating FGF21 in morbidly obese subjects

H. Pijl, P. Jansen, F. Schaap, 2014, Clinical endocrinology.

Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01)

H. Pijl, H. Guchelaar, S. Böhringer, 2016, Breast Cancer Research.

Calorie Restriction is a Major Determinant of the Short‐Term Metabolic Effects of Gastric Bypass Surgery in Obese Type 2 Diabetic Patients

H. Pijl, E. Aarts, I. Janssen, 2014, Clinical endocrinology.

Time-Dependent Effects of Low-Dose Aspirin on Plasma Renin Activity, Aldosterone, Cortisol, and Catecholamines

H. Pijl, J. D. Snoep, M. Huisman, 2009, Hypertension.

Psychological and metabolic responses of carbohydrate craving obese patients to carbohydrate, fat and protein-rich meals

H. Pijl, A. Meinders, W. Onkenhout, 1997, International Journal of Obesity.

Decrease in visceral fat following diet-induced weight loss in upper body compared to lower body obese premenopausal women.

H. Pijl, A. Meinders, J. Langendonk, 2006, European journal of internal medicine.

Microvascular complications in patients with cystic fibrosis-related diabetes (CFRD).

H. Pijl, H. Heijerman, A. Morton, 2008, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Brain activity and connectivity changes in response to nutritive natural sugars, non-nutritive natural sugar replacements and artificial sweeteners

S. Rombouts, H. Pijl, M. Hoeksma, 2019, Nutritional neuroscience.

Brain activity and connectivity changes in response to glucose ingestion

S. Rombouts, H. Pijl, M. Hoeksma, 2020, Nutritional neuroscience.

Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance Published, JLR Papers in Press, October 1, 2003. DOI 10.1194/jlr.M300240-JLR200

H. Pijl, J. Romijn, R. Mensink, 2004, Journal of Lipid Research.

The Effect of Multidisciplinary Lifestyle Intervention on the Pre- and Postprandial Plasma Gut Peptide Concentrations in Children with Obesity

H. Pijl, E. V. van Zwet, J. Wit, 2011, ISRN endocrinology.

Renal contribution to increased clearance of exogenous growth hormone in obese hypertensive patients.

H. Pijl, A. Kroon, P. D. de Leeuw, 2005, The Journal of clinical endocrinology and metabolism.

Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss

Jeroen F. J. Laros, H. Pijl, P. Hoen, 2014, Diabetologia.

Prolactin Secretion in Healthy Adults Is Determined by Gender, Age and Body Mass Index

D. M. Keenan, H. Pijl, J. Veldhuis, 2012, PloS one.

Altered multihormone synchrony in obese patients with polycystic ovary syndrome.

H. Pijl, J. Veldhuis, F. Roelfsema, 2011, Metabolism: clinical and experimental.

Growth hormone secretion in primary adrenal Cushing's syndrome is disorderly and inversely correlated with body mass index.

H. Pijl, J. Romijn, J. Veldhuis, 2005, American journal of physiology. Endocrinology and metabolism.

The effect of dietary phytosphingosine on cholesterol levels and insulin sensitivity in subjects with the metabolic syndrome

H. Pijl, J. Romijn, L. Havekes, 2010, European Journal of Clinical Nutrition.

Individual and partner's level of occupation and the association with HbA1c levels in people with Type 2 diabetes mellitus: the Dutch Diabetes Pearl cohort

H. Pijl, O. Dekkers, G. Nijpels, 2017, Diabetic medicine : a journal of the British Diabetic Association.

A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-alpha protein concentration in ApoE-3*Leiden mice.

H. Pijl, J. Romijn, R. Mensink, 2003, The Journal of nutrition.

Human visceral adipose tissue and the plasminogen activator inhibitor type 1

P. Eilers, H. Pijl, T. Kooistra, 2007, International Journal of Obesity.

Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass.

H. Pijl, F. Koning, I. Janssen, 2016, Metabolism: clinical and experimental.

Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance.

H. Pijl, R. Toes, F. Koning, 2014, Metabolism: clinical and experimental.

Circadian rhythm of plasma leptin levels in upper and lower body obese women: influence of body fat distribution and weight loss.

H. Pijl, J. Doornbos, A. Meinders, 1998, The Journal of clinical endocrinology and metabolism.

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

H. Pijl, J. Romijn, Yanan Wang, 2015, Diabetologia.

Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation

H. Pijl, B. Everts, M. Wijngaarden, 2021, Proceedings of the National Academy of Sciences.

Insulin and leptin concentrations in obese humans during long-term weight loss.

H. Pijl, R. Westendorp, A. Meinders, 1997, The Netherlands journal of medicine.

Adipocytes Modulate the Phenotype of Human Macrophages through Secreted Lipids

H. Pijl, M. Giera, T. Huizinga, 2013, The Journal of Immunology.

Familial Longevity Is Marked by Lower Diurnal Salivary Cortisol Levels: The Leiden Longevity Study

H. Pijl, A. D. de Craen, P. Slagboom, 2012, PloS one.

Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults

H. Pijl, R. Adan, J. Seidell, 2006, International Journal of Obesity.

Reduction of plasma leptin levels and loss of its circadian rhythmicity in hypocretin (orexin)-deficient narcoleptic humans.

H. Pijl, S. Overeem, F. Roelfsema, 2002, The Journal of clinical endocrinology and metabolism.

Ghrelin and the hyposomatotropism of obesity.

H. Pijl, T. Kooistra, J. Lindeman, 2002, Obesity research.

Serum leptin in normal-weight and obese humans.

H. Pijl, A. Meinders, A. Toornvliet, 1996, The New England journal of medicine.

The decline in plasma leptin in response to calorie restriction predicts the effects of adjunctive leptin treatment on body weight in humans.

H. Pijl, M. Mccamish, M. Frölich, 2003, European journal of internal medicine.

Insulin Sensitivity in De Novo Parkinson's Disease: A Hyperinsulinemic‐Euglycemic Clamp Study

H. Pijl, R. Roos, N. Aziz, 2020, Movement disorders : official journal of the Movement Disorder Society.

Huntington disease: clinical consequences and therapeutic implications

H. Pijl, D. Swaab, N. Aziz, 2007 .

Oxyntomodulin ameliorates glucose intolerance in mice fed a high-fat diet.

H. Pijl, J. Romijn, A. Heijboer, 2008, American journal of physiology. Endocrinology and metabolism.

Selenium Supplementation for Hashimoto's Thyroiditis: Summary of a Cochrane Systematic Review

Z. Fedorowicz, H. Pijl, E. V. van Zuuren, 2013, European Thyroid Journal.

Neuroendocrinology of Human Narcolepsy

H. Pijl, S. Overeem, G. Lammers, 2006 .

The effects of carbohydrate variation in isocaloric diets on glycogenolysis and gluconeogenesis in healthy men.

H. Pijl, J. Romijn, A. Meijer, 2000, The Journal of clinical endocrinology and metabolism.

CNTO736, a Novel Glucagon-Like Peptide-1 Receptor Agonist, Ameliorates Insulin Resistance and Inhibits Very Low-Density Lipoprotein Production in High-Fat-Fed Mice

H. Pijl, J. Romijn, K. O'Neil, 2009, Journal of Pharmacology and Experimental Therapeutics.

Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice.

H. Pijl, J. Romijn, A. Heijboer, 2007, American journal of physiology. Endocrinology and metabolism.

Chronic PYY 3 – 36 treatment promotes fat oxidation and ameliorates insulin resistance in C 57 BL 6 mice

H. Pijl, J. Romijn, A. Heijboer, 2006 .

Chapter 4 PYY 3-36 reinforces insulin action on glucose disposal in m ice fed a high fat diet

H. Pijl, J. Romijn, A. Heijboer, 2006 .

Chapter 5 Chronic PYY 3-36 treatm ent am eliorates insulin resistance in C 57 BL 6-mice on a high fat diet

H. Pijl, J. Romijn, A. Heijboer, 2006 .

Endothelial function in patients with hyperthyroidism before and after treatment with propranolol and thiamazol.

H. Pijl, A. Cohen, S. Lalezari, 2001, Thyroid : official journal of the American Thyroid Association.

Leptin Deficiency Per Se Dictates Body Composition and Insulin Action in ob/ob Mice

B. Teusink, H. Pijl, J. Romijn, 2007, Journal of neuroendocrinology.

Leptin deficiency per se dictates body com position, insulin action and insulin clearance in ob/ob mice

B. Teusink, H. Pijl, J. Romijn, 2006 .

Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes

H. Pijl, M. Giera, K. Willems van Dijk, 2015, Nutrients.

Increased PUFA content and 5-lipoxygenase pathway activity are associated with subcutaneous adipose tissue inflammation in obese women

H. Pijl, M. Giera, M. Lips, 2015 .

Factors predicting the blood glucose lowering effect of a 30‐day very low calorie diet in obese Type 2 diabetic patients

H. Pijl, A. Meinders, I. Jazet, 2005, Diabetic medicine : a journal of the British Diabetic Association.

Prolonged Caloric Restriction in Obese Patients With Type 2 Diabetes Mellitus Decreases Plasma CETP and Increases Apolipoprotein AI Levels Without Improving the Cholesterol Efflux Properties of HDL

H. Pijl, H. Lamb, J. Romijn, 2011, Diabetes Care.

Long‐Term Beneficial Effect of a 16‐Week Very Low Calorie Diet on Pericardial Fat in Obese Type 2 Diabetes Mellitus Patients

H. Pijl, H. Lamb, A. Roos, 2012, Obesity.

Intracerebroventricular adm inistration of m elanotan II increases insulin sensitivity of glucose disposal in m ice

H. Pijl, J. Romijn, A. Heijboer, 2006 .

Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice

H. Pijl, P. Voshol, L. Havekes, 2005, Diabetologia.

Food choice in hyperthyroidism: potential influence of the autonomic nervous system and brain serotonin precursor availability.

H. Pijl, A. Meinders, A. Cohen, 2001, Journal of Clinical Endocrinology and Metabolism.

Specific stimulation of brain serotonin mediated neurotransmission by dexfenfluramine does not restore growth hormone responsiveness in obese women

H. Pijl, H. Schoemaker, A. Cohen, 1996, Clinical endocrinology.

Roux-en-Y gastric bypass and calorie restriction induce comparable time-dependent effects on thyroid hormone function tests in obese female subjects.

H. Pijl, B. van Ramshorst, J. A. Smit, 2013, European journal of endocrinology.

Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndrome.

H. Pijl, J. Veldhuis, F. Roelfsema, 2004, American journal of physiology. Endocrinology and metabolism.

Co-publication of articles from the Netherlands Drug Bulletin 183

H. Pijl, I. Jazet, D. Bijl, 2003 .

Sustained cardiac remodeling after a short-term very low calorie diet in type 2 diabetes mellitus patients

H. Pijl, H. Lamb, J. Romijn, 2013, The International Journal of Cardiovascular Imaging.

Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake.

B. Teusink, H. Pijl, J. Romijn, 2003, Diabetes.

Cortisol production rate is similarly elevated in obese women with or without the polycystic ovary syndrome.

H. Pijl, F. Roelfsema, A. Pereira, 2010, The Journal of clinical endocrinology and metabolism.

thyroid hormone function tests in obese female subjects. 2

H. Pijl, I. Janssen, M. Lips, 2013 .

Bromocriptine reduces augmented thyrotropin secretion in obese premenopausal women.

H. Pijl, J. van Pelt, F. Roelfsema, 2009, The Journal of clinical endocrinology and metabolism.

Effect of serotonin re-uptake inhibition by fluoxetine on body weight and spontaneous food choice in obesity.

H. Pijl, A. Meinders, H. Koppeschaar, 1991, International journal of obesity.

GLP-1 treatment reduces endogenous insulin resistance via activation of central GLP-1 receptors in mice fed a high-fat diet.

H. Pijl, J. Romijn, J. E. de Leeuw van Weenen, 2010, American journal of physiology. Endocrinology and metabolism.

Disordered and increased adrenocorticotropin secretion with diminished adrenocorticotropin potency in obese in premenopausal women.

H. Pijl, F. Roelfsema, M. Frolich, 2009, The Journal of clinical endocrinology and metabolism.

Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese women

H. Pijl, F. Koning, K. V. Dijk, 2014, International Journal of Obesity.

Energy restriction and Roux-en-Y gastric bypass reduce postprandial α-dicarbonyl stress in obese women with type 2 diabetes

H. Pijl, C. Stehouwer, C. Schalkwijk, 2016, Diabetologia.

Observational study on dietary changes of participants following a multicomponent lifestyle program (Reverse Diabetes2 Now).

H. Pijl, P. Voshol, G. Pot, 2021, Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.

Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimicking diet in patients with type 2 diabetes

H. Pijl, H. Lamb, M. Numans, 2020, BMC Endocrine Disorders.

The effects of high fat diet on the basal activity of the hypothalamus-pituitary-adrenal axis in mice.

H. Pijl, J. Romijn, L. Havekes, 2012, The Journal of endocrinology.

Plasma total ghrelin and leptin levels in human narcolepsy and matched healthy controls: basal concentrations and response to sodium oxybate.

H. Pijl, S. Overeem, N. Aziz, 2013, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

Renal clearance of endogenous leptin in hypertensive humans with or without renal artery stenosis.

H. Pijl, A. Kroon, P. D. de Leeuw, 2001, American journal of physiology. Endocrinology and metabolism.

Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013–14) trial

H. Pijl, H. Gelderblom, V. Longo, 2020, Breast Cancer Research and Treatment.

Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice

H. Pijl, A. Heijboer, L. Havekes, 2006, Diabetologia.

Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1

H. Pijl, V. Dahlmans, S. Koopmans, 2001, Diabetologia.

Very low calorie diets and recently developed anti-obesity drugs for treating overweight in non-insulin dependent diabetics.

H. Pijl, A. Meinders, 1990, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets.

J. Holst, J. Rehfeld, H. Pijl, 2010, European journal of endocrinology.

Short-term treatment with Olanzapine does not modulate gut hormone

J. Holst, J. Rehfeld, H. Pijl, 2009 .

Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients.

T. Stijnen, H. Pijl, J. Romijn, 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

practice applications LETTERS TO THE EDITOR Snacking and Obesity: Urgency of a Definition to Explore such a Relationship

R. Wurtman, H. Pijl, R. Gleason, 2007 .

Diminished Adrenal Sensitivity and Adrenocorticotropin

D. M. Keenan, H. Pijl, F. Roelfsema, 2012 .

Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity

S. H. van der Burg, H. Pijl, J. Kroep, 2022, Cancers.

The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study

H. Putter, H. Pijl, M. Welters, 2015, BMC Cancer.

Adipose tissue as an endocrine organ: impact on insulin resistance.

H. Pijl, A. Meinders, A. Meinders, 2003, The Netherlands journal of medicine.

The effect of family-based multidisciplinary cognitive behavioral treatment on health-related quality of life in childhood obesity

H. Pijl, J. Wit, R. Vos, 2012, Quality of Life Research.

The Effect of a Lifestyle Intervention on Type 2 Diabetes Pathophysiology and Remission: The Stevenshof Pilot Study

H. Pijl, W. Otten, S. Wopereis, 2021, Nutrients.

The prevalence of the metabolic syndrome is increased in patients with GH deficiency, irrespective of long-term substitution with recombinant human GH.

E. Feskens, H. Pijl, J. Romijn, 2007, European journal of endocrinology.

No effect of consumption of green and black tea on plasma lipid and antioxidant levels and on LDL oxidation in smokers.

H. Pijl, A. Meinders, H. Princen, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Olanzapine shifts the temporal relationship between the daily acrophase of serum prolactin and cortisol concentrations rhythm in healthy men

H. Pijl, F. Roelfsema, S. Vidarsdóttir, 2009, Psychoneuroendocrinology.

Phase difference between serum prolactin and cortisol rhythms is related to body mass index in humans.

H. Pijl, F. Roelfsema, 2012, The Journal of clinical endocrinology and metabolism.

Modulation of Monoaminergic Neural Circuits

H. Pijl, E. Meinders, 2002 .

Sodium oxybate increases prolactin secretion in narcolepsy patients and healthy controls.

H. Pijl, S. Overeem, N. Aziz, 2011, European Journal of Endocrinology.

Altered thyrotropic and lactotropic axes regulation in Huntington’s disease

H. Pijl, F. Roelfsema, R. Roos, 2010, Clinical endocrinology.

Pharmacological Modulation of Dopamine Receptor D2-Mediated Transmission Alters the Metabolic Phenotype of Diet Induced Obese and Diet Resistant C57Bl6 Mice

H. Pijl, K. Willems van Dijk, J. E. de Leeuw van Weenen, 2011, Experimental diabetes research.

Pulsatile LH release is diminished, whereas FSH secretion is normal, in hypocretin-deficient narcoleptic men.

S Overeem, H. Pijl, S. Overeem, 2004, American journal of physiology. Endocrinology and metabolism.

Four weeks high fat feeding induces insulin resistance without affecting dopamine release or gene expression patterns in the hypothalamus of C57Bl6 mice

H. Pijl, J. Tamsma, J. V. Weenen, 2009, Brain Research.

Unraveling the Resistance of IGF-Pathway Inhibition in Ewing Sarcoma

H. Pijl, H. Gelderblom, J. Kroep, 2020, Cancers.

Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans

M. McCarthy, R. Scharfmann, H. Pijl, 2015, Diabetes.

A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice.

H. Pijl, R. Mensink, L. Havekes, 2002, Metabolism: clinical and experimental.

Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature

H. Pijl, A. D. de Craen, N. Aziz, 2017, BMJ Open Diabetes Research and Care.

Effects of short-term fasting on cancer treatment

H. Pijl, J. V. D. van der Hoeven, J. Kroep, 2019, Journal of experimental & clinical cancer research : CR.

Dynamic metabolomic data analysis: a tutorial review

A. K. Smilde, J. A. Westerhuis, H. C. J. Hoefsloot, 2009, Metabolomics.

Soluble mannose receptor induces pro-inflammatory macrophage activation and obesity-associated metaflammation

H. Pijl, B. Everts, K. V. van Dijk, 2020, bioRxiv.

The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells.

H. Pijl, J. Romijn, L. Havekes, 2010, Biochemical pharmacology.

Acipimox enhances spontaneous growth hormone secretion in obese women.

H. Pijl, F. Roelfsema, A. Meinders, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions

H. Pijl, H. Pijl, H. Lamb, 2012, International journal of endocrinology.

Sympathovagal imbalance in hyperthyroidism.

H. Pijl, A. Meinders, A. Cohen, 2001, American journal of physiology. Endocrinology and metabolism.

Repeat length variations in polyglutamine disease-associated genes affect body mass index

H. Pijl, R. Roos, P. Slagboom, 2018, International Journal of Obesity.

GLP-1 Receptor Activation Inhibits VLDL Production and Reverses Hepatic Steatosis by Decreasing Hepatic Lipogenesis in High-Fat-Fed APOE*3-Leiden Mice

Hanno Pijl, Patrick C. N. Rensen, H. Pijl, 2012, PloS one.

Obesity, dopamine and the metabolic syndrome: potential of dopaminergic agents in the control of metabolism

H. Pijl, J. Romijn, 2006 .

obesity : evolution of a symptom of affluence . How food has shaped our existence

H. Pijl, 2022 .

The Impact of Obesity and Lifestyle on the Immune System and Susceptibility to Infections Such as COVID-19

D. Atsma, H. Pijl, J. Seidell, 2020, Frontiers in Nutrition.

Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients

H. Pijl, J. Maassen, J. Romijn, 2007, Diabetologia.

Gut–Brain Axis: Regulation of Glucose Metabolism

H. Pijl, J. Romijn, L. Havekes, 2006, Journal of neuroendocrinology.

From Diabetes Care to Diabetes Cure—The Integration of Systems Biology, eHealth, and Behavioral Change

Mattijs E. Numans, Ben van Ommen, Hanno Pijl, 2018, Front. Endocrinol..

Somatotropic axis in hypocretin-deficient narcoleptic humans: altered circadian distribution of GH-secretory events.

H. Pijl, S. Overeem, A. Vein, 2003, American journal of physiology. Endocrinology and metabolism.

Exploratory analysis of candidate germline gene polymorphisms in breast cancer patients treated with neoadjuvant anthracycline-containing chemotherapy and associations with febrile neutropenia.

H. Pijl, H. Gelderblom, T. van der Straaten, 2015, Pharmacogenomics.

Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism.

H. Pijl, C. Wijbrandts, J. Romijn, 2003, The American journal of clinical nutrition.

Metabolic impact of intermittent energy restriction and periodic fasting in patients with type 2 diabetes: a systematic review

H. Pijl, M. Numans, Petra G. van Peet, 2023, Nutrition reviews.

Roux-en-Y Gastric Bypass Surgery, but Not Calorie Restriction, Reduces Plasma Branched-Chain Amino Acids in Obese Women Independent of Weight Loss or the Presence of Type 2 Diabetes

Thomas Hankemeier, Gert-Jan van Ommen, Hanno Pijl, 2014, Diabetes Care.

Effects of bariatric surgery on pericardial ectopic fat depositions and cardiovascular function

H. Pijl, H. Lamb, A. Roos, 2014, Clinical endocrinology.

Familial longevity is marked by enhanced insulin sensitivity

H. Pijl, S. le Cessie, P. Slagboom, 2011, Aging Cell.

Effect of diet-induced weight loss on lipoprotein(a) levels in obese individuals with and without type 2 diabetes

F. Kronenberg, H. Pijl, E. Sijbrands, 2017, Diabetologia.

Consumption of black and green tea has no effect on inflammation, haemostasis and endothelial markers in smoking healthy individuals

H. Pijl, C. Kluft, H. Princen, 2000, European Journal of Clinical Nutrition.

Borderline personality, impulsiveness, and platelet monoamine measures in bulimia nervosa and recurrent suicidal behavior

H. Pijl, R. Verkes, A. Meinders, 1996, Biological Psychiatry.

The Impact of Dairy Products in the Development of Type 2 Diabetes: Where Does the Evidence Stand in 2019?

D. I. Givens, A. Astrup, H. Pijl, 2019, Advances in nutrition.

Prolactin release is enhanced in proportion to excess visceral fat in obese women.

H. Pijl, F. Roelfsema, A. Meinders, 2004, The Journal of clinical endocrinology and metabolism.

Increased circadian prolactin release is blunted after body weight loss in obese premenopausal women.

H. Pijl, F. Roelfsema, A. Meinders, 2006, American journal of physiology. Endocrinology and metabolism.

body weight loss in obese premenopausal women Increased circadian prolactin release is blunted after

H. Pijl, F. Roelfsema, C. C. D. Wit, 2016 .

Activation of dopamine D2 receptors simultaneously ameliorates various metabolic features of obese women.

Hanno Pijl, Ferdinand Roelfsema, Marijke Frölich, 2006, American journal of physiology. Endocrinology and metabolism.

Disease‐specific impairments in quality of life during long‐term follow‐up of patients with different pituitary adenomas

H. Pijl, O. Dekkers, J. Romijn, 2008, Clinical endocrinology.

High circulating thyrotropin levels in obese women are reduced after body weight loss induced by caloric restriction.

H. Pijl, F. Roelfsema, A. Meinders, 2005, The Journal of clinical endocrinology and metabolism.

The effect of aripiprazole and quinagolide, a dopamine agonist, in a patient with symptomatic pituitary prolactinoma and chronic psychosis.

H. Pijl, E. Giltay, M. Gosselink, 2012, General hospital psychiatry.

Spontaneous diurnal thyrotropin secretion is enhanced in proportion to circulating leptin in obese premenopausal women.

H. Pijl, F. Roelfsema, A. Meinders, 2005, The Journal of clinical endocrinology and metabolism.

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

H. Pijl, P. Slagboom, R. Westendorp, 2015, Scientific Reports.

Characterization of the Hypothalamic-Pituitary-Adrenal-Axis in Familial Longevity under Resting Conditions

H. Pijl, R. Westendorp, D. van Heemst, 2015, PloS one.

Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

H. Pijl, P. Slagboom, R. Westendorp, 2019, The Journal of clinical endocrinology and metabolism.

Effects of low-carbohydrate- compared with low-fat-diet interventions on metabolic control in people with type 2 diabetes: a systematic review including GRADE assessments.

Z. Fedorowicz, H. Pijl, T. Kuijpers, 2018, The American journal of clinical nutrition.

High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort

H. Pijl, J. Dekker, F. Rutters, 2018, Diabetes Care.

Glucose Ingestion Fails to Inhibit Hypothalamic Neuronal Activity in Patients With Type 2 Diabetes

Jeroen van der Grond, Max A Viergever, Hanno Pijl, 2007, Diabetes.

Omega-3 fatty acids in heart disease—why accurately measured levels matter

H. Pijl, C. von Schacky, D. Grobbee, 2023, Netherlands Heart Journal.

Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function.

Hanno Pijl, Marieke Snel, Albert de Roos, 2008, Journal of the American College of Cardiology.

Diurnal Secretion Profiles of Growth Hormone, Thyrotrophin and Prolactin in Parkinson’s Disease

H. Pijl, F. Roelfsema, R. Roos, 2011, Journal of neuroendocrinology.

Reduced dopaminergic tone in hypothalamic neural circuits: expression of a "thrifty" genotype underlying the metabolic syndrome?

H. Pijl, 2003, European journal of pharmacology.

Obesity is marked by distinct functional connectivity in brain networks involved in food reward and salience

H. Pijl, S. Rombouts, H. Pijl, 2015, Behavioural Brain Research.

Resting-state functional connectivity of brain regions involved in cognitive control, motivation, and reward is enhanced in obese females.

Jeroen van der Grond, Hanno Pijl, Serge A R B Rombouts, 2014, The American journal of clinical nutrition.

Blocking Dopamine D2 Receptors by Haloperidol Curtails the Beneficial Impact of Calorie Restriction on the Metabolic Phenotype of High‐Fat Diet Induced Obese Mice

H. Pijl, O. Meijer, C. Coomans, 2011, Journal of neuroendocrinology.

Dietary sugars and non-caloric sweeteners elicit different homeostatic and hedonic responses in the brain.

H. Pijl, M. Hoeksma, J. van der Grond, 2019, Nutrition.

The effect of consumption temperature on the homeostatic and hedonic responses to glucose ingestion in the hypothalamus and the reward system.

S. Rombouts, H. Pijl, M. Hoeksma, 2018, The American journal of clinical nutrition.

The Predictive Value of the Individual Components of the Metabolic Syndrome for Insulin Resistance in Obese Children

H. Pijl, J. Wit, R. Vos, 2011, Hormone Research in Paediatrics.

Longevity. The allostatic load of dietary restriction

H. Pijl, 2012, Physiology & Behavior.

A 5-Day High-Fat, High-Calorie Diet Impairs Insulin Sensitivity in Healthy, Young South Asian Men but Not in Caucasian Men

H. Pijl, H. Lamb, J. Smit, 2013, Diabetes.

Lifestyle medicine for type 2 diabetes: practice-based evidence for long-term efficacy of a multicomponent lifestyle intervention (Reverse Diabetes2 Now)

H. Pijl, N. J. van der Zijl, P. Voshol, 2020, BMJ nutrition, prevention & health.

Experience with a totally implantable venous access device (Port-A-Cath) in patients with AIDS.

H. Pijl, P. Frissen, 1992 .

Thyroid function alters during neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01)

H. Putter, H. Pijl, V. Smit, 2015, Breast Cancer Research and Treatment.

Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity.

H. Pijl, S. Overeem, J. Seidell, 2003, Obesity research.

Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals

H. Pijl, P. Slagboom, R. Noordam, 2016, Aging cell.

Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic

H. Pijl, O. Dekkers, E. D. de Koning, 2021, BMJ Open Diabetes Research & Care.

Intracerebroventricular Administration of Neuropeptide Y Induces Hepatic Insulin Resistance via Sympathetic Innervation

H. Pijl, A. Kalsbeek, J. Romijn, 2008, Diabetes.

Quality of life in type 2 diabetes mellitus after a very low calorie diet and exercise.

Hanno Pijl, Marieke Snel, H. Pijl, 2012, European journal of internal medicine.

Obesity is associated with an altered autonomic nervous system response to nutrient restriction

H. Pijl, M. Wijngaarden, J. Burggraaf, 2013, Clinical endocrinology.

Modulation of monoaminergic neural circuits: potential for the treatment of type 2 diabetes mellitus.

H. Pijl, A. Edo, 2002, Treatments in endocrinology.

The effect of family-based multidisciplinary cognitive behavioral treatment in children with obesity: study protocol for a randomized controlled trial

H. Pijl, J. Wit, R. Vos, 2011, Trials.

Orally disintegrating and standard olanzapine tablets similarly elevate the HOMA insulin resistance index and plasma triglyceride levels in healthy men

H. Pijl, F. Roelfsema, S. Vidarsdóttir, 2010 .

Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity and glycogen synthesis.

H. Pijl, M. Matsuda, R. Pipek, 2001, American journal of physiology. Endocrinology and metabolism.

Nutrition and lifestyle intervention in type 2 diabetes: pilot study in the Netherlands showing improved glucose control and reduction in glucose lowering medication

H. Pijl, R. Witkamp, M. D. De Vries, 2019, BMJ Nutrition, Prevention & Health.

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

H. Pijl, K. V. van Dijk, M. Wijngaarden, 2014, American journal of physiology. Endocrinology and metabolism.

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.

H. Pijl, K. V. van Dijk, M. Wijngaarden, 2013, American journal of physiology. Endocrinology and metabolism.

in skeletal muscle from lean and obese individuals expression, and mitochondrial respiratory chain content Effects of prolonged fasting on AMPK signaling, gene

H. Pijl, M. Wijngaarden, K. W. Dijk, 2013 .

Growth hormone blunts protein oxidation and promotes protein turnover to a similar extent in abdominally obese and normal-weight women.

H. Pijl, J. Romijn, M. D. de Kam, 2002, The Journal of clinical endocrinology and metabolism.

Familial Longevity Is Not Associated with Major Differences in the Hypothalamic–Pituitary–Gonadal Axis in Healthy Middle-Aged Men

H. Pijl, P. Slagboom, R. Westendorp, 2016, Front. Endocrinol..

Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship.

H. Pijl, P. Slagboom, R. Westendorp, 2015, The Journal of clinical endocrinology and metabolism.

Stress, serotonergic function, and mood in users of oral contraceptives

H. Pijl, D. Fekkes, H. Koppeschaar, 1995, Psychoneuroendocrinology.

Systemic energy homeostasis in Huntington's disease patients

H. Pijl, R. Roos, N. Aziz, 2010, Journal of Neurology, Neurosurgery & Psychiatry.

Tumor‐stroma ratio is associated with Miller‐Payne score and pathological response to neoadjuvant chemotherapy in HER2‐negative early breast cancer

H. Pijl, W. Mesker, E. Kranenbarg, 2020, International journal of cancer.

Regulation of skeletal muscle energy/nutrient-sensing pathways during

H. Pijl, M. Wijngaarden, K. W. Dijk, 2014 .

PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat diet.

H. Pijl, J. Romijn, A. Heijboer, 2004, Diabetes.

Recombinant human GH replacement increases CD34+ cells and improves endothelial function in adults with GH deficiency.

H. Pijl, J. Romijn, T. Rabelink, 2008, European journal of endocrinology.

Activation of dopamine D2 receptors lowers circadian leptin concentrations in obese women.

H. Pijl, J. van Pelt, F. Roelfsema, 2006, The Journal of clinical endocrinology and metabolism.

The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy

H. Pijl, E. V. van Someren, S. Overeem, 2015, Journal of sleep research.

Altered Circadian Rhythm of Melatonin Concentrations in Hypocretin-Deficient Men

H. Pijl, A. Kalsbeek, S. Overeem, 2012, Chronobiology international.

Effect of sodium oxybate on growth hormone secretion in narcolepsy patients and healthy controls.

H. Pijl, S. Overeem, N. Aziz, 2011, American journal of physiology. Endocrinology and metabolism.

1 The effect of sodium oxybate on growth hormone secretion 2 in narcolepsy patients and healthy controls 3 4 5

H. Pijl, S. Overeem, N. Aziz, 2011 .

Autonomic nervous system activity in diabetic and healthy obese female subjects and the effect of distinct weight loss strategies.

H. Pijl, M. D. de Kam, J. Burggraaf, 2013, European journal of endocrinology.

Increased heart rate variability but normal resting metabolic rate in hypocretin/orexin-deficient human narcolepsy.

H. Pijl, S. Overeem, J. G. van Dijk, 2008, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

Oral glucose intake inhibits hypothalamic neuronal activity more effectively than glucose infusion.

M. Viergever, H. Pijl, M. V. van Osch, 2007, American journal of physiology. Endocrinology and metabolism.

The 24-hour serum profiles of bone markers in healthy older men and women.

H. Pijl, R. Cachucho, D. van Heemst, 2019, Bone.

Long-term effect of lifestyle intervention on adiposity, metabolic parameters, inflammation and physical fitness in obese children: a randomized controlled trial

H. Pijl, J. Wit, R. Vos, 2011, Nutrition & Diabetes.

Effects of adding exercise to a 16-week very low-calorie diet in obese, insulin-dependent type 2 diabetes mellitus patients.

H. Pijl, J. Romijn, A. Gastaldelli, 2012, The Journal of clinical endocrinology and metabolism.

Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1.

H. Pijl, J. Romijn, L. Havekes, 2001, Diabetes.

Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals

Hanno Pijl, Diana van Heemst, H. Pijl, 2015, PloS one.

Thyrotropin secretion in healthy subjects is robust and independent of age and gender, and only weakly dependent on body mass index.

H. Pijl, E. Fliers, J. Veldhuis, 2014, The Journal of clinical endocrinology and metabolism.

Spontaneous food choice in narcolepsy.

H. Pijl, A. Meinders, G. Lammers, 1996, Sleep.

Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease.

H. Pijl, R. Roos, J. Romijn, 2009, The Journal of clinical endocrinology and metabolism.

Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01)

H. Putter, H. Pijl, M. Pepels, 2019, Breast Cancer Research.

Short-term treatment with bromocriptine improves impaired circadian growth hormone secretion in obese premenopausal women.

H. Pijl, J. van Pelt, F. Roelfsema, 2008, The Journal of clinical endocrinology and metabolism.

Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy

H. Pijl, H. Gelderblom, J. V. D. van der Hoeven, 2017, OncoTargets and therapy.

Orally disintegrating and oral standard olanzapine tablets similarly elevate the homeostasis model assessment of insulin resistance index and plasma triglyceride levels in 12 healthy men: a randomized crossover study.

H. Pijl, F. Roelfsema, S. Vidarsdóttir, 2010, The Journal of clinical psychiatry.

Enhanced circadian ACTH release in obese premenopausal women: reversal by short-term acipimox treatment.

H. Pijl, F. Roelfsema, M. Stokkel, 2004, American journal of physiology. Endocrinology and metabolism.

Leptin secretion rate increases with higher CAG repeat number in Huntington’s disease patients

H. Pijl, R. Roos, F. Roelfsema, 2010, Clinical endocrinology.

Exophthalmos in Obesity

H. Pijl, A. Fogteloo, A. Meinders, 2004, Ophthalmic Research.

The muscle–liver axis: does aerobic fitness induce intrahepatic protection against non‐alcoholic fatty liver disease?

H. Pijl, J. Romijn, 2009, The Journal of physiology.

[New drugs; exenatide and sitagliptin].

H. Pijl, A. Cohen, H. van Bronswijk, 2008, Nederlands tijdschrift voor geneeskunde.

Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed growth hormone secretion.

S. O’Rahilly, H. Pijl, I. Farooqi, 2011, The Journal of clinical endocrinology and metabolism.

Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome.

H. Pijl, J. Veldhuis, F. Roelfsema, 2002, The Journal of clinical endocrinology and metabolism.

Altered neuroregulation of GH secretion in viscerally obese premenopausal women.

H. Pijl, J. Veldhuis, A. Meinders, 2001, The Journal of clinical endocrinology and metabolism.

Response to Comment on: Teeuwisse et al. Short-Term Caloric Restriction Normalizes Hypothalamic Neuronal Responsiveness to Glucose Ingestion in Patients With Type 2 Diabetes. Diabetes 2012;61:3255–3259

H. Pijl, J. van der Grond, R. Widya, 2013, Diabetes.

Short-Term Caloric Restriction Normalizes Hypothalamic Neuronal Responsiveness to Glucose Ingestion in Patients With Type 2 Diabetes

Jeroen van der Grond, Hildo J. Lamb, Hanno Pijl, 2012, Diabetes.

Circadian distribution of motor activity and immobility in narcolepsy: assessment with continuous motor activity monitoring.

H. Pijl, H. Kamphuisen, H. Middelkoop, 1995, Psychophysiology.

Predictors of weight loss during treatment with d‐fenfluramine

H. Pijl, A. Meinders, A. Toornvliet, 1997, Journal of internal medicine.

Obesity: evolution of a symptom of affluence.

H. Pijl, 2011, The Netherlands journal of medicine.

The Diabetes Pearl: Diabetes biobanking in The Netherlands

H. Pijl, G. Nijpels, J. Dekker, 2012, BMC Public Health.

Altered setting of the pituitary-thyroid ensemble in hypocretin-deficient narcoleptic men.

H. Pijl, S. Overeem, F. Roelfsema, 2005, American journal of physiology. Endocrinology and metabolism.

High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice

H. Pijl, E. Corssmit, E. Donga, 2005, Peptides.

Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice.

H. Pijl, J. Romijn, R. Mensink, 2003, Metabolism: clinical and experimental.

Cardiovascular flexibility in middle-aged overweight South Asians vs. white Caucasians: response to short-term caloric restriction.

H. Pijl, H. Lamb, A. de Roos, 2015, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Food Cues Do Not Modulate the Neuroendocrine Response to a Prolonged Fast in Healthy Men

Maurice B. Bizino, H. Pijl, M. van Buchem, 2012, Neuroendocrinology.

Growth hormone and ghrelin secretion are associated with clinical severity in Huntington’s disease

H. Pijl, N. Aziz, F. Roelfsema, 2010, European journal of neurology.

The influence of serotonergic neurotransmission on pituitary hormone release in obese and non-obese females.

H. Pijl, A. Meinders, H. Koppeschaar, 1993, Acta endocrinologica.

Effects of short-term fasting on cancer treatment

H. Pijl, J. V. D. van der Hoeven, J. Kroep, 2019, Journal of Experimental & Clinical Cancer Research.

hypocretin-deficient narcoleptic men Altered setting of the pituitary-thyroid ensemble in

H. Pijl, S. Overeem, F. Roelfsema, 2016 .

Major depression during dexfenfluramine treatment.

H. Pijl, A. Meinders, A. Toornvliet, 1994, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Effects of recombinant human leptin treatment as an adjunct of moderate energy restriction on body weight, resting energy expenditure and energy intake in obese humans.

H. Pijl, A. Fogteloo, A. Meinders, 2003, Diabetes, nutrition & metabolism.

Effectiveness of a hospital‐based vascular screening programme (SMART) for risk factor management in patients with established vascular disease or type 2 diabetes: a parallel‐group comparative study

A. Algra, H. Pijl, E. E. van der Wall, 2010, Journal of internal medicine.

Sustained cardiac remodeling after a short-term very low calorie diet in type 2 diabetes mellitus

H. Pijl, H. Lamb, J. Romijn, 2011, Journal of Cardiovascular Magnetic Resonance.

Leptin, adiponectin, and resistin secretion and diurnal rhythmicity are unaltered in Parkinson's disease

H. Pijl, N. Aziz, F. Roelfsema, 2011, Movement disorders : official journal of the Movement Disorder Society.

Dynamics of the pituitary-adrenal ensemble in hypocretin-deficient narcoleptic humans: blunted basal adrenocorticotropin release and evidence for normal time-keeping by the master pacemaker.

H. Pijl, R. Strijers, S. Overeem, 2002, The Journal of clinical endocrinology and metabolism.

Sex‐specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

T. Hansen, O. Pedersen, N. Grarup, 2014, Diabetic medicine : a journal of the British Diabetic Association.

Effects of intranasal insulin application on the hypothalamic BOLD response to glucose ingestion

H. Pijl, R. Westendorp, J. Grond, 2017, Scientific Reports.

Gut–brain axis

H. Pijl, J. Romijn, L. Havekes, 2008, Current opinion in clinical nutrition and metabolic care.

Lifestyle Medicine: Why Do We Need It?

H. Pijl, 2018, Medical Science Educator.

Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation

H. Pijl, B. Everts, M. Wijngaarden, 2021, Proceedings of the National Academy of Sciences.

Endocrine pulse identification using penalized methods and a minimum set of assumptions.

Age K Smilde, Johan A Westerhuis, Jan van der Greef, 2010, American journal of physiology. Endocrinology and metabolism.

Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis.

Z. Fedorowicz, H. Pijl, E. Manheimer, 2015, The American journal of clinical nutrition.

Intensive Lifestyle (e)Support to Reverse Diabetes-2

Catholijn M. Jonker, Ben van Ommen, Hildo J. Lamb, 2016, Bled eConference.

Plasma total ghrelin and leptin levels in human narcolepsy and matched healthy controls: basal concentrations and response to sodium oxybate.

H. Pijl, S. Overeem, F. Roelfsema, 2013, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

The effect of consumption temperature on the homeostatic and hedonic responses to glucose ingestion in the hypothalamus and the reward system.

S. Rombouts, H. Pijl, M. Hoeksma, 2018, The American journal of clinical nutrition.

Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship.

H. Pijl, R. Westendorp, D. van Heemst, 2015, The Journal of clinical endocrinology and metabolism.

Weight loss and exercise in obese older adults.

H. Pijl, R. Roos, N. Aziz, 2011, The New England journal of medicine.

Low serum cholesterol and serotonin metabolism; results may have been affected by confounding : letter to the editor

H. Pijl, J. Leuven, G. Kempen, 1996 .

The prevalence of the metabolic syndrome is increased in patients with GH deficiency, irrespective of long-term substitution with recombinant human GH.

E. Feskens, H. Pijl, J. Romijn, 2007, European journal of endocrinology.

Bromocriptine: a novel approach to the treatment of type 2 diabetes.

J. Lancaster, H. Pijl, S. Ohashi, 2000, Diabetes care.

The effect of family-based multidisciplinary cognitive behavioral treatment in children with obesity: study protocol for a randomized controlled trial

H. Pijl, J. Wit, R. Vos, 2011, Trials.

The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity. By Stephen J. Simpson and David Raubenheimer. xii + 239 pp. Princeton, NJ: Princeton University Press. 2012. $49.50 (cloth or ebook).

H. Pijl, 2013 .

Tumor‐stroma ratio is associated with Miller‐Payne score and pathological response to neoadjuvant chemotherapy in HER2‐negative early breast cancer

H. Pijl, W. Mesker, E. Kranenbarg, 2021, International journal of cancer.

Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease.

H. Pijl, R. Roos, J. Romijn, 2009, The Journal of clinical endocrinology and metabolism.