H. Münzberg

发表

Central control of autonomic functions in health and disease

S. McDougall, H. Münzberg, A. Derbenev, 2015, Front. Neurosci..

The lateral hypothalamus as integrator of metabolic and environmental needs: From electrical self-stimulation to opto-genetics

H. Berthoud, H. Münzberg, 2011, Physiology & Behavior.

Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.

H. Münzberg, T. Horvath, R. Seeley, 2009, Cell metabolism.

Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action.

H. Münzberg, Yan Zhang, A. Laque, 2013, American journal of physiology. Endocrinology and metabolism.

Leptin-Receptor-Expressing Neurons in the Dorsomedial Hypothalamus and Median Preoptic Area Regulate Sympathetic Brown Adipose Tissue Circuits

H. Münzberg, Yan Zhang, C. Rhodes, 2011, The Journal of Neuroscience.

Glutamatergic Preoptic Area Neurons That Express Leptin Receptors Drive Temperature-Dependent Body Weight Homeostasis

H. Berthoud, H. Münzberg, A. Derbenev, 2016, The Journal of Neuroscience.

1 The PYY / Y 2 R-deficient mouse responds normally to 2 high-fat diet and gastric bypass surgery 3

H. Münzberg, C. Morrison, Sangho Yu, 2019 .

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

H. Berthoud, H. Münzberg, C. Morrison, 2019, Nutrients.

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

H. Berthoud, H. Münzberg, C. Morrison, 2019, Nutrients.

GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents.

N. Stylopoulos, H. Berthoud, H. Münzberg, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Leptin-signaling pathways and leptin resistance.

H. Münzberg, 2010 .

Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.

H. Münzberg, M. Björnholm, M. Myers, 2007, The Journal of clinical investigation.

Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature.

H. Münzberg, G. Heldmaier, S. Klaus, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of signal transducer and activator of transcription 3 in regulation of hypothalamic trh gene expression by leptin.

H. Münzberg, E. Nillni, L. Huo, 2004, Endocrinology.

Homeostatic sensing of dietary protein restriction: A case for FGF21

H. Berthoud, H. Münzberg, C. Morrison, 2018, Frontiers in Neuroendocrinology.

Roux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice

H. Berthoud, H. Münzberg, Jianping Ye, 2016, Molecular metabolism.

FGF21 is an endocrine signal of protein restriction.

G. Bray, L. Redman, H. Münzberg, 2014, The Journal of clinical investigation.

IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery

H. Berthoud, H. Münzberg, A. Carpentier, 2020, Cell Reports Medicine.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, J. D. Tompkins, Rosemary C Challis, 2018, Nature Communications.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, J. D. Tompkins, Rosemary C Challis, 2018, bioRxiv.

Ventilatory capacity and risk for dementia.

P. Schlattmann, B. Geiselmann, H. Münzberg, 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

Comparison of the diagnostic potential of four echocardiographic stress tests shortly after acute myocardial infarction: submaximal exercise, transesophageal atrial pacing, dipyridamole, and dobutamine-atropine.

H. Münzberg, H. Völler, H. Schultheiss, 1996, The American journal of cardiology.

Differential leptin access into the brain — A hierarchical organization of hypothalamic leptin target sites?

H. Münzberg, 2008, Physiology & Behavior.

Missense variants in the human peroxisome proliferator-activated receptor-gamma2 gene in lean and obese subjects.

H. Münzberg, J. Hebebrand, A. Hinney, 1999, European journal of endocrinology.

New Insights into the Regulation of Leptin Gene Expression.

S. Heymsfield, H. Münzberg, 2019, Cell metabolism.

Leptin Therapy in People with a Normal Leptin Gene

S. Heymsfield, H. Münzberg, 2015 .

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.

H. Münzberg, A. Zsombok, Suhuan Liu, 2018, JCI insight.

Central mechanisms of adiposity in adult female mice with androgen excess

H. Münzberg, F. Mauvais-Jarvis, A. Laque, 2014, Obesity.

IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery

H. Berthoud, H. Münzberg, A. Carpentier, 2020, Cell reports. Medicine.

Leptin, Obesity, and Leptin Resistance

S. Heymsfield, H. Münzberg, 2015 .

Evolving Concepts of Leptin

H. Münzberg, T. Gettys, 2013 .

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

H. Berthoud, H. Münzberg, C. Morrison, 2019, Nutrients.

Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints

H. Berthoud, H. Münzberg, D. McDougal, 2017, Scientific Reports.

Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2.

H. Berthoud, H. Münzberg, T. Gettys, 2016, Cell reports.

Does gastric bypass surgery change body weight set point?

H. Berthoud, H. Münzberg, C. Morrison, 2016, International journal of obesity supplements.

Analysis of the uncoupling protein-1 (UCP1) gene in obese and lean subjects: Identification of four amino acid variants

H. Münzberg, J. Hebebrand, A. Hinney, 1998, International Journal of Obesity.

Sympathetic Innervation of White Adipose Tissue: to Beige or Not to Beige?

H. Münzberg, J. Chang, E. Floyd, 2021, Physiology.

gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.

H. Münzberg, T. Horvath, M. Shanabrough, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Roux-en-Y Gastric Bypass Surgery-Induced Weight Loss and Metabolic Improvements Are Similar in TGR5-Deficient and Wildtype Mice

H. Berthoud, H. Münzberg, T. Gettys, 2018, Obesity Surgery.

Preoptic leptin signaling modulates energy balance independent of body temperature regulation

H. Berthoud, H. Münzberg, A. Derbenev, 2018, eLife.

Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice

H. Berthoud, H. Münzberg, C. Rhodes, 2019, Molecular metabolism.

Reprogramming of defended body weight after Roux‐En‐Y gastric bypass surgery in diet‐induced obese mice

H. Berthoud, H. Münzberg, Jianping Ye, 2016, Obesity.

FGF21 is required for protein restriction to extend lifespan and improve metabolic health in male mice

H. Berthoud, H. Münzberg, A. Bartke, 2022, Nature communications.

Leptin deficient ob/ob mice and diet-induced obese mice responded differently to Roux-en-Y bypass surgery

H. Berthoud, H. Münzberg, Jianping Ye, 2014, International Journal of Obesity.

RYGB Produces more Sustained Body Weight Loss and Improvement of Glycemic Control Compared with VSG in the Diet-Induced Obese Mouse Model

H. Berthoud, H. Münzberg, C. Morrison, 2017, Obesity Surgery.

Leptin Receptor Signaling and Action in the Central Nervous System

H. Münzberg, M. Björnholm, M. Myers, 2006, Obesity.

Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade

N. Stylopoulos, H. Berthoud, H. Münzberg, 2014, Obesity.

Gastric bypass surgery in lean adolescent mice prevents diet-induced obesity later in life

H. Berthoud, H. Münzberg, C. Morrison, 2019, Scientific Reports.

Identification of a deletion variant in the gene encoding the human alpha(2A)-adrenergic receptor.

H. Münzberg, J. Hebebrand, A. Hinney, 2001, European journal of endocrinology.

The Hypothalamic Preoptic Area and Body Weight Control

H. Münzberg, Sangho Yu, Marie Francois, 2017, Neuroendocrinology.

A guide to analysis of mouse energy metabolism

Robert V Farese, E. Ravussin, R. Eckel, 2011, Nature Methods.

Body Composition, Food Intake, and Energy Expenditure in a Murine Model of Roux-en-Y Gastric Bypass Surgery

H. Berthoud, H. Münzberg, Jianping Ye, 2016, Obesity Surgery.

Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low 3

H. Münzberg, Roy J Martin, S. Hutson, 2014 .

Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry.

H. Münzberg, Sangho Yu, 2018, Bio-protocol.

N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptin.

H. Münzberg, E. Nillni, C. Bjørbaek, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of leptin action and leptin resistance.

Heike Münzberg, H. Münzberg, M. Myers, 2008, Annual review of physiology.

Structure, production and signaling of leptin.

H. Münzberg, C. Morrison, 2015, Metabolism: clinical and experimental.

Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

C. Saper, L. Ferrari, E. Arrigoni, 2018, Nature Communications.

Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus.

H. Münzberg, Roy J Martin, S. Hutson, 2012, The Journal of endocrinology.

Leptin receptor action and mechanisms of leptin resistance

H. Münzberg, M. Björnholm, M. Myers, 2005, Cellular and Molecular Life Sciences.

Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity

H. Berthoud, H. Münzberg, Sangho Yu, 2021, Molecular metabolism.

Early-life exposure to testosterone programs the hypothalamic melanocortin system.

H. Münzberg, R. Waraich, Yan Zhang, 2011, Endocrinology.

Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

H. Münzberg, J. Flier, C. Bjørbaek, 2004, Endocrinology.

Direct Innervation of GnRH Neurons by Metabolic- and Sexual Odorant-Sensing Leptin Receptor Neurons in the Hypothalamic Ventral Premammillary Nucleus

H. Münzberg, Y. Jo, M. Myers, 2009, The Journal of Neuroscience.

Phenotyping of nNOS neurons in the postnatal and adult female mouse hypothalamus

H. Münzberg, V. Prévot, E. Hrabovszky, 2017, The Journal of comparative neurology.

Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status.

H. Münzberg, R. Seeley, D. Fingar, 2009, Endocrinology.

Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.

D. Ingram, H. Münzberg, P. Pistell, 2013, Cell metabolism.

Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake

Heike Münzberg, H. Münzberg, A. Derbenev, 2014, Molecular metabolism.

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.

F. Ashcroft, Xiaosong Ma, T. Mak, 2006, The Journal of clinical investigation.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, G. Salama, V. Gradinaru, 2018, bioRxiv.

Critical roles for the TSC-mTOR pathway in β-cell function.

H. Münzberg, K. Inoki, O. MacDougald, 2009, American journal of physiology. Endocrinology and metabolism.

Critical role for hypothalamic mTOR activity in energy balance.

H. Münzberg, K. Inoki, O. MacDougald, 2009, Cell metabolism.

Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and Regulate Cocaine- and Amphetamine-Regulated Transcript Neurons of the Extended Central Amygdala

H. Münzberg, M. Myers, C. Rhodes, 2010, The Journal of Neuroscience.

Neural Control of Energy Expenditure.

H. Berthoud, H. Münzberg, C. Morrison, 2016, Handbook of experimental pharmacology.

Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat

H. Münzberg, B. Neel, B. Kahn, 2015, Cell.

Novel aspects of brown adipose tissue biology.

H. Münzberg, J. Heeren, 2013, Endocrinology and metabolism clinics of North America.

Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low dietary protein.

H. Münzberg, Roy J Martin, S. Hutson, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

FGF21 and the Physiological Regulation of Macronutrient Preference

H. Berthoud, H. Münzberg, D. McDougal, 2020, Endocrinology.

Protein Appetite at the Interface between Nutrient Sensing and Physiological Homeostasis

H. Berthoud, H. Münzberg, C. Morrison, 2021, Nutrients.

Sympathetic innervation of the interscapular brown adipose tissue in mouse

H. Berthoud, H. Münzberg, C. Morrison, 2019, Annals of the New York Academy of Sciences.

The geometry of leptin action in the brain: more complicated than a simple ARC.

H. Münzberg, M. Myers, G. Leinninger, 2009, Cell metabolism.

Blaming the Brain for Obesity: Integration of Hedonic and Homeostatic Mechanisms.

H. Berthoud, H. Münzberg, C. Morrison, 2017, Gastroenterology.

The Long Form of the Leptin Receptor Regulates STAT5 and Ribosomal Protein S6 via Alternate Mechanisms*

H. Münzberg, D. Fingar, M. Myers, 2007, Journal of Biological Chemistry.

Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature.

H. Münzberg, G. Heldmaier, S. Klaus, 1998, American Journal of Physiology.

Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin.

H. Münzberg, A. Hollenberg, E. Nillni, 2003, Endocrinology.

Molecular and anatomical determinants of central leptin resistance

H. Münzberg, M. Myers, 2005, Nature Neuroscience.

Hedonics Act in Unison with the Homeostatic System to Unconsciously Control Body Weight

H. Berthoud, H. Münzberg, C. Morrison, 2016, Front. Nutr..

Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice

L. Redman, H. Münzberg, Sujoy Ghosh, 2021, BMC genomics.

Capricious Cre: the devil is in the details.

H. Münzberg, C. Morrison, 2012, Endocrinology.

Genetics-based manipulation of adipose tissue sympathetic innervation

H. Berthoud, H. Münzberg, Sangho Yu, 2017, Physiology & Behavior.

Neural and metabolic regulation of macronutrient intake and selection

H. Berthoud, H. Münzberg, C. Morrison, 2012, Proceedings of the Nutrition Society.

Galanin-Expressing GABA Neurons in the Lateral Hypothalamus Modulate Food Reward and Noncompulsive Locomotion

H. Berthoud, H. Münzberg, A. Bruce-Keller, 2017, The Journal of Neuroscience.

Appetite and body weight regulation after bariatric surgery

H. Berthoud, H. Münzberg, A. Laque, 2015, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Organization of sympathetic innervation of interscapular brown adipose tissue in the mouse

H. Berthoud, H. Münzberg, W. Neuhuber, 2021, The Journal of comparative neurology.

Carotid atherosclerosis, vascular risk profile and mortality in a population‐based sample of functionally healthy elderly subjects: the Berlin Ageing Study

H. Münzberg, E. Steinhagen-Thiessen, T. Hillen, 2000, Journal of internal medicine.

Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity

H. Münzberg, A. Husch, P. Kloppenburg, 2009, The Journal of Neuroscience.

Galanin Regulates Myocardial Mitochondrial ROS Homeostasis and Hypertrophic Remodeling Through GalR2

H. Münzberg, J. Roncalli, O. Kunduzova, 2022, Frontiers in Pharmacology.

Lateral hypothalamic galanin neurons are activated by stress and blunt anxiety-like behavior in mice

L. Lecea, H. Münzberg, Joshua Owens-French, 2022, Behavioural Brain Research.

Regulation of body weight: Lessons learned from bariatric surgery

H. Berthoud, H. Münzberg, C. Morrison, 2022, Molecular metabolism.

The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed?

H. Berthoud, H. Münzberg, C. Morrison, 2020, Physiology & Behavior.

Integration of sensory information via central thermoregulatory leptin targets

H. Münzberg, K. Rezai-zadeh, 2013, Physiology & Behavior.

Modulation of Feeding and Associated Behaviors by Lateral Hypothalamic Circuits

Heike Münzberg, H. Münzberg, Emily Qualls-Creekmore, 2018, Endocrinology.

Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints

H. Berthoud, H. Münzberg, D. McDougal, 2017, Scientific Reports.

Recent advances in understanding the role of leptin in energy homeostasis

S. Heymsfield, H. Münzberg, Prachi Singh, 2020, F1000Research.

Mechanisms Responsible for Metabolic Improvements of Bariatric Surgeries

H. Berthoud, H. Münzberg, J. Kirwan, 2018, Diabetes.

Eating in mice with gastric bypass surgery causes exaggerated activation of brainstem anorexia circuit

H. Berthoud, H. Münzberg, Jianping Ye, 2016, International Journal of Obesity.

N-acetylation of hypothalamic α-melanocyte-stimulating hormone and regulation by leptin

H. Münzberg, E. Nillni, Christian Bjørbæk, 2004 .

Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

H. Berthoud, H. Münzberg, A. Laque, 2015, Molecular metabolism.

Appropriate Inhibition of Orexigenic Hypothalamic Arcuate Nucleus Neurons Independently of Leptin Receptor/STAT3 Signaling

H. Münzberg, J. Elmquist, M. Björnholm, 2007, The Journal of Neuroscience.

Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

C. Saper, L. Ferrari, E. Arrigoni, 2018, Nature Communications.

European Obesity Summit (EOS) – Joint Congress of EASO and IFSO-EC, Gothenburg, Sweden, June 1 – 4, 2016: Abstracts

Parashu Ram Pal, S. A. Todd, Jimmy D Bell, 2016, Obesity Facts.

Sympathetic innervation of inguinal white adipose tissue in the mouse

H. Berthoud, H. Münzberg, W. Neuhuber, 2020, The Journal of comparative neurology.

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.

H. Münzberg, T. Horvath, M. Shanabrough, 2007, Cell metabolism.

Differential accessibility of circulating leptin to individual hypothalamic sites.

H. Münzberg, M. Björnholm, M. Faouzi, 2007, Endocrinology.

Animal Models of Obesity: Perspectives on Evolution of Strategies for Their Development and Analysis of Their Phenotypes

H. Münzberg, T. Gettys, T. Henagan, 2014 .

Thrifty Phenotype: Effect of Gender Glycerol-3-phosphate Dehydrogenase Gene Exhibit a Mice with Deletion of the Mitochondrial Diet-sensitive Obesity Enhanced Pip3 Signaling in Pomc Neurons Causes Katp Channel Activation and Leads To

F. Ashcroft, C. Bouchard, Xiaosong Ma, 2006 .

Screening for variability in the ciliary neurotrophic factor (CNTF) gene: No evidence for association with human obesity

H. Münzberg, J. Hebebrand, A. Hinney, 2009, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Regulation of leptin receptor‐expressing neurons in the brainstem by TRPV1

H. Münzberg, A. Derbenev, A. Zsombok, 2014, Physiological reports.

Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.

D. Ingram, H. Münzberg, P. Pistell, 2013, Cell metabolism.

FGF21 is an endocrine signal of protein restriction.

G. Bray, L. Redman, H. Münzberg, 2014, The Journal of clinical investigation.

Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin.

H. Münzberg, A. Hollenberg, E. Nillni, 2003, Endocrinology.

FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

Stephen J. Simpson, H. Berthoud, H. Münzberg, 2019, Cell reports.

Sensory spinal interoceptive pathways and energy balance regulation

H. Berthoud, H. Münzberg, Winfried L. Neuhuber, 2023, Molecular metabolism.

Neural and metabolic regulation of macronutrient intake and selection

H. Münzberg, H. Berthoud, Brenda K. Richards, 2012, Proceedings of the Nutrition Society.

Symposium on 'Metabolic flexibility in animal and human nutrition' Session III: Appetite regulation: Neural and metabolic regulation of macronutrient intake and selection

H. Berthoud, H. Münzberg, C. Morrison, 2012 .

Hepatic interoception in health and disease

H. Münzberg, Christopher D. Morrison, Winfried L. Neuhuber, 2024, Autonomic Neuroscience.

FGF21 as a mediator of adaptive changes in food intake and macronutrient preference in response to protein restriction

H. Münzberg, Sangho Yu, Redin A. Spann, 2024, Neuropharmacology.

History and future of leptin: Discovery, regulation and signaling.

H. Münzberg, Christopher D. Morrison, H.-R. Berthoud, 2024, Metabolism: clinical and experimental.

FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling

H. Münzberg, D. McDougal, Sangho Yu, 2024, bioRxiv.