J. Desmet

发表

The fuzzy-end elimination theorem: correctly implementing the side chain placement algorithm based on the dead-end elimination theorem.

I. Lasters, J. Desmet, Johan Desmet, 1993, Protein engineering.

Conformational splitting: A more powerful criterion for dead‐end elimination

S. L. Mayo, N. Pierce, J. Desmet, 2000, J. Comput. Chem..

Development of a thick film ammonia sensor for livestock buildings

J. Roggen, G Huyberechts, M. Honore, 1994 .

Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.

S E Hufton, J. Desmet, T. van den Beucken, 2001, Journal of molecular biology.

Flexible docking of peptide ligands to proteins.

I. Lasters, J. Desmet, J. Spriet, 2000, Methods in molecular biology.

Computation of the binding of fully flexible peptides to proteins with flexible side chains

I Lasters, M De Maeyer, I. Wilson, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

High performance liquid chromatography stability study of malonyl-coenzyme A, using statistical experimental designs.

J. Desmet, B. De Spiegeleer, K. Sintobin, 1989, Biomedical chromatography : BMC.

The dead-end elimination theorem: mathematical aspects, implementation, optimizations, evaluation, and performance.

I Lasters, M De Maeyer, I. Lasters, 2000, Methods in molecular biology.

Anchor profiles of HLA‐specific peptides: Analysis by a novel affinity scoring method and experimental validation

I. Lasters, N. Boutonnet, J. Desmet, 2004, Proteins.

Formal copolymers based on 1,3-dithienylisothianaphthene derivatives : Promising materials for electronic devices

P. Adriaensens, J. Gelan, J. Desmet, 1998 .

Rational humanization of the powerful antithrombotic anti-GPIbα antibody: 6B4

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and Haemostasis.

A novel class of pore-forming peptides in the venom of parabuthus schlechteri Purcell (scorpions: buthidae)

J. Desmet, F. Verdonck, J. Tytgat, 2000 .

Complexes of the polyamines spermine, spermidine and putrescine with alpha-lactalbumins.

J. Desmet, M. Joniau, L. Morozova, 1993, European journal of biochemistry.

Coexistence of hypocalciuric hypercalcaemia and interstitial lung disease in a family: a cross‐sectional study

J. Auwerx, J. Desmet, R. Bouillon, 1985, European journal of clinical investigation.

Affinity maturation by semi-rational approaches.

J. Desmet, J. Casal, R. Barderas, 2012, Methods in molecular biology.

Novel scorpion K+ channel toxins isolated from venoms of species belonging to the Parabuthus genus

J. Desmet, J. Tytgat, P. Daenens, 1998 .

Humanization by Resurfacing

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2010 .

In Silico De-Immunization

I. Lasters, J. Desmet, P. Alard, 2010 .

Clavis Patrum Graecorum

J. Desmet, F. Winkelmann, M. Geerard, 1974 .

Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

I. Lasters, J. Desmet, S. Savvides, 2021, Science Advances.

Synthesis and characterization of tin dioxide powders for the realization of thick-film gas sensors

J. Desmet, S. Lenaerts, J. Roggen, 1994 .

Diagnostic and treatment issues in postamputation pain after landmine injury.

J. Desmet, R. Harden, P. Wiffen, 2006, Pain medicine.

Enhanced antigenicity of a four-contact-residue epitope of the measles virus hemagglutinin protein by phage display libraries: evidence of a helical structure in the putative active site.

J. Desmet, K. E. El Kasmi, P. Fournier, 1998, Molecular immunology.

Liver-FunctionStudies in Heart-Transplant RecipientsTreated with CyclosporinA

J. Desmet, M. Adler, J. Leclerc, 1988 .

The dead-end elimination theorem and its use in protein side-chain positioning

Johan Desmet, Marc De Maeyer, Bart Hazes, 1992, Nature.

All in one: a highly detailed rotamer library improves both accuracy and speed in the modelling of sidechains by dead-end elimination.

I Lasters, M De Maeyer, I. Lasters, 1997, Folding & design.

Structural basis of IL-23 antagonism by an Alphabody protein scaffold

I. Lasters, J. Desmet, S. Savvides, 2014, Nature Communications.

Affinity maturation of antibodies assisted by in silico modeling

Peter Timmerman, J Ignacio Casal, Rodrigo Barderas, 2008, Proceedings of the National Academy of Sciences.

Fast and accurate side‐chain topology and energy refinement (FASTER) as a new method for protein structure optimization

I. Lasters, J. Desmet, J. Spriet, 2002, Proteins.

The effect of metal ion binding on protein stability

J. Desmet, M. Joniau, H. Dael, 1993 .

The Dead-End Elimination Theorem:

Marc De Maeyer, I. Lasters, J. Desmet, 2000 .

Development and application of cytotoxic T lymphocyte‐associated antigen 4 as a protein scaffold for the generation of novel binding ligands

J. Desmet, H. Hoogenboom, S. Hufton, 2000, FEBS letters.

A Ca2+-binding Chimera of Human Lysozyme and Bovine α-Lactalbumin That Can Form a Molten Globule (*)

C M Dobson, C. Dobson, J. Desmet, 1995, The Journal of Biological Chemistry.

Comparison of the binding of Ca2+ and Mn2+ to bovine α-lactalbumin and equine lysozyme

J. Desmet, S. Sugai, K. Nitta, 1989 .

Calorimetric experiments of Mn2+-binding to α-lactalbumin

J. Desmet, F. V. Cauwelaert, 1988 .

Comparison of the binding of Na+ and Ca2+ to bovine α-lactalbumin

J. Desmet, I. Hanssens, F. V. Cauwelaert, 1987 .

Binding of CDR‐derived peptides is mechanistically different from that of high‐affinity parental antibodies

J. Desmet, D. Altschuh, R. Meloen, 2010, Journal of molecular recognition : JMR.

A Combinatorial Approach for the Design of Complementarity-determining Region-derived Peptidomimetics with in Vitro Anti-tumoral Activity*

J. Desmet, D. Altschuh, R. Meloen, 2009, The Journal of Biological Chemistry.

Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and haemostasis.

Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.

Karen Vanhoorelbeke, J. Desmet, H. Deckmyn, 2006, Molecular immunology.

Enhanced dead-end elimination in the search for the global minimum energy conformation of a collection of protein side chains.

I Lasters, M De Maeyer, J Desmet, 1995, Protein engineering.

Conformational splitting: A more powerful criterion for dead-end elimination

Stephen L. Mayo, Niles A. Pierce, Jan A. Spriet, 2000, J. Comput. Chem..

Theoretical and algorithmical optimization of the dead-end elimination theorem.

I Lasters, M De Maeyer, J Desmet, 1997, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.