D. Wiley

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The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.

S. Schreiber, S. Harrison, G. Zhou, 2000, Bioorganic & medicinal chemistry.

Refinement of the influenza virus hemagglutinin by simulated annealing.

J. Skehel, D. Wiley, A. Brünger, 1991, Journal of molecular biology.

Structure of influenza haemagglutinin at the pH of membrane fusion

J. Skehel, D. Wiley, P. Bullough, 1994, Nature.

Structural characterization of a soluble and partially folded class I major histocompatibility heavy chain/β2m heterodimer

D. Wiley, M. Bouvier, 1998, Nature Structural Biology.

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.

J. Skehel, D. Wiley, 2000, Annual review of biochemistry.

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

J. Skehel, D. Wiley, L. González-Reyes, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

I. Wilson, J. Skehel, D. Wiley, 1981, Nature.

Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes.

J. Skehel, D. Wiley, S. Martin, 1986, Virology.

The receptor‐binding and membrane‐fusion properties of influenza virus variants selected using anti‐haemagglutinin monoclonal antibodies.

J. Skehel, D. Wiley, J. Paulson, 1987, The EMBO journal.

Studies on the structure of the influenza virus haemagglutinin at the pH of membrane fusion.

J. Skehel, D. Wiley, W. Weis, 1988, The Journal of general virology.

A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation.

W. Weissenhorn, J. Skehel, D. Wiley, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Coiled Coils in Both Intracellular Vesicle and Viral Membrane Fusion

J. Skehel, D. Wiley, John J Skehel, 1998, Cell.

N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.

J. Skehel, D. Wiley, J. Chen, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The structure and function of the hemagglutinin membrane glycoprotein of influenza virus.

J. Skehel, D. Wiley, D C Wiley, 1987, Annual review of biochemistry.

Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles.

J. Skehel, D. Wiley, D. Steinhauer, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the Hemagglutinin Precursor Cleavage Site, a Determinant of Influenza Pathogenicity and the Origin of the Labile Conformation

David J Stevens, J. Skehel, D. Wiley, 1998, Cell.

H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes

Ya Ha, J. Skehel, D. Wiley, 2002, The EMBO journal.

The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin

D. J. Stevens, J. Skehel, D. Wiley, 2004, Science.

Analyses of the antigenicity of influenza haemagglutinin at the pH optimum for virus-mediated membrane fusion.

J. Skehel, D. Wiley, A. Douglas, 1983, The Journal of general virology.

Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation.

J. Skehel, D. Wiley, R. Ruigrok, 1995, The EMBO journal.

X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.

Ya Ha, David J Stevens, J. Skehel, 2003, Virology.

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs

J. Skehel, D. Wiley, D. Stevens, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

I. Wilson, J. Skehel, D. Wiley, 1981, Nature.

Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.

I. Wilson, J. Skehel, D. Wiley, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Electron microscopy of influenza haemagglutinin-monoclonal antibody complexes.

J. Skehel, D. Wiley, A. Douglas, 1983, Virology.

Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity

I. Wilson, J. Skehel, D. Wiley, 1983, Nature.

Antigenic analyses of influenza virus haemagglutinins with different receptor-binding specificities.

C. Naeve, R. Webster, J. Skehel, 1984, Virology.

Studies on the adaptation of influenza viruses to MDCK cells.

J. Skehel, D. Wiley, H. Klenk, 1984, The EMBO journal.

Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin

M. Knossow, J. Skehel, D. Wiley, 1984, Nature.

Host-mediated selection of influenza virus receptor variants. Sialic acid-alpha 2,6Gal-specific clones of A/duck/Ukraine/1/63 revert to sialic acid-alpha 2,3Gal-specific wild type in ovo.

J. Skehel, D. Wiley, J. Paulson, 1985, The Journal of biological chemistry.

Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

S. Cusack, J. Skehel, D. Wiley, 1988, Nature.

Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study.

G M Whitesides, G. Whitesides, J. Skehel, 1989, Biochemistry.

Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.

J. Skehel, D. Wiley, J. H. Brown, 1994, Biochemistry.

Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin.

M B Eisen, M. Eisen, J. Knowles, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region.

J. J. Rosa, D. Wiley, J. Rosal, 1992, The EMBO journal.

Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs.

S. Watowich, J. Skehel, D. Wiley, 1994, Structure.

A surface plasmon resonance assay for the binding of influenza virus hemagglutinin to its sialic acid receptor.

J. Skehel, D. Wiley, D. Takemoto, 1996, Virology.

Binding of the influenza A virus to cell-surface receptors: structures of five hemagglutinin-sialyloligosaccharide complexes determined by X-ray crystallography.

M B Eisen, M. Eisen, J. Skehel, 1997, Virology.

A polar octapeptide fused to the N-terminal fusion peptide solubilizes the influenza virus HA2 subunit ectodomain.

J. Skehel, D. Wiley, J. Chen, 1998, Biochemistry.

Studies of the binding properties of influenza hemagglutinin receptor-site mutants.

J. Skehel, D. Wiley, D. Steinhauer, 1998, Virology.

The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2

D. Wiley, D. Garboczi, D. Madden, 1993, Cell.

Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.

D. Wiley, U. Utz, D. Garboczi, 1998, Immunity.

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

D. Wiley, J. Strominger, T. Jardetzky, 1993, Nature.

Structure of the human class I histocompatibility antigen, HLA-A2

M. A. Saper, D. Wiley, J. Strominger, 1987, Nature.

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

M. A. Saper, D. Wiley, J. Strominger, 1990, Nature.

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.

D. Wiley, P. Bjorkman, M. Saper, 1991, Journal of molecular biology.

Structure of the human class I histocompatibility antigen, HLA-A2.

D. Wiley, J. Strominger, P. Bjorkman, 2005, Journal of immunology.

Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro

R. Klausner, D. Wiley, T. Ottenhoff, 1994, Nature.

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.

D. Wiley, J. Strominger, T. Jardetzky, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Atomic structure of a human MHC molecule presenting an influenza virus peptide

Don C. Wiley, D. Wiley, J. Strominger, 1992, Nature.

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.

B M Baker, D. Wiley, D. Garboczi, 1999, Immunity.

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

D. Wiley, D. Garboczi, D. T. Hung, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

Partho Ghosh, Don C. Wiley, D. Wiley, 1995, Nature.

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

Partho Ghosh, Don C. Wiley, D. Wiley, 1996, Nature.

The Structure and Stability of an HLA-A*0201/Octameric Tax Peptide Complex with an Empty Conserved Peptide-N-Terminal Binding Site1

Partho Ghosh, Brian M. Baker, Don C. Wiley, 2000, The Journal of Immunology.

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

Don C. Wiley, D. Wiley, J. Strominger, 1994, Nature.

2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei.

D. Wiley, M. Carrington, M. Turner, 1990, Journal of molecular biology.

HOOK: A program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site

M Karplus, R E Hubbard, M B Eisen, 1994, Proteins.

Structure, Function, and Antigenicity of the Hemagglutinin of Influenza Virus

Don C. Wiley, J. Skehel, D. Wiley, 1989 .

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

Don C. Wiley, Bing Chen, Haiyun Gong, 2005 .

Peptide binding to HLA‐DR1: a peptide with most residues substituted to alanine retains MHC binding.

D. Wiley, J. Strominger, J. Rothbard, 1990, The EMBO journal.

Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.

D. Wiley, J. Strominger, T. Jardetzky, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.

D. Wiley, D. Garboczi, M. Karpusas, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Membrane fusion by influenza hemagglutinin.

J. Skehel, D. Wiley, P. Bullough, 1995, Cold Spring Harbor symposia on quantitative biology.

Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies.

J. Skehel, D. Wiley, L. González-Reyes, 2000, Virology.

Receptor-binding characteristics of monoclonal antibody-selected antigenic variants of influenza virus

J. Skehel, D. Wiley, P. Underwood, 1987, Journal of virology.

Membrane fusion by peptide analogues of influenza virus haemagglutinin.

J. Skehel, D. Wiley, S. Martin, 1988, The Journal of general virology.

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation.

D. Zaller, D. Wiley, L. Mosyak, 1998, Immunity.

Identification of the Lateral Interaction Surfaces of Human Histocompatibility Leukocyte Antigen (HLA)-DM with HLA-DR1 by Formation of Tethered Complexes That Present Enhanced HLA-DM Catalysis

D. Zaller, D. Wiley, L. Mosyak, 2002, Journal of Experimental Medicine.

Peptide binding to the major histocompatibility complex molecules: Current Opinion in Structural Biology 1992, 2:300–304

D. Wiley, D. Madden, 1992 .

The human class II MHC protein HLA-DR1 assembles as empty αβ heterodimers in the absence of antigenic peptide

D. Wiley, L. Stern, 1992, Cell.

Human class II MHC molecule HLA-DR1: X-ray structure determined from three crystal forms.

D. Wiley, J. Strominger, T. Jardetzky, 1995, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X‐ray diffraction studies of the human major histocompatibility antigen HLA‐B27

D. Wiley, J. Strominger, D. Madden, 1992, Proteins.

The class I and class II proteins of the human major histocompatibility complex

D. Wiley, J. Strominger, 1995 .

Crystallization of HLA-DR antigens.

D. Wiley, J. Strominger, T. Jardetzky, 1991, Research in immunology.

Enhanced Catalytic Action of HLA-DM on the Exchange of Peptides Lacking Backbone Hydrogen Bonds between their N-Terminal Region and the MHC Class II α-Chain1

D. Wiley, L. Stern, E. Stratikos, 2004, The Journal of Immunology.

An HLA-A2/beta 2-microglobulin/peptide complex assembled from subunits expressed separately in Escherichia coli.

K. Parker, D. Wiley, M. L. Silver, 1992, Molecular immunology.

Crystallization and preliminary X-ray analysis of an intact soluble-form variant surface glycoprotein from the African trypanosome, Trypanosoma brucei.

D. Wiley, M. Turner, S. Garman, 1991, Journal of molecular biology.

Biochemical and functional analyses of a secreted H-2Ld molecule

J. Seidman, K. Parker, D. Wiley, 1986, Molecular and cellular biology.

Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule.

Eric O Long, D. Wiley, D. Garboczi, 1996, Proceedings of the National Academy of Sciences of the United States of America.

CRYSTAL STRUCTURE OF HLA-CW4, A LIGAND FOR THE KIR2D NATURAL KILLER CELL INHIBITORY RECEPTOR

D. Wiley, Q. Fan, 1999 .

Cobalt-mediated Dimerization of the Human Natural Killer Cell Inhibitory Receptor*

Eric O Long, D. Wiley, Q. Fan, 2000, The Journal of Biological Chemistry.

Overexpression of native human β-microglobulin in Escherichia coli and its purification

K. Parker, D. Wiley, 1989 .

Purification of Complexes between Peptide Antigens and Class II Major Histocompatibility Complex Antigens Using Biotinylated Peptides

D. Wiley, J. Strominger, J. Rothbard, 1989 .

Crystallization and X-ray diffraction studies on the histocompatibility antigens HLA-A2 and HLA-A28 from human cell membranes.

D. Wiley, J. Strominger, P. Bjorkman, 1985, Journal of molecular biology.

MHC class II function preserved by low-affinity peptide interactions preceding stable binding

D. Wiley, R. Germain, L. Stern, 1994, Nature.

Antigenic peptides containing large PEG loops designed to extend out of the HLA-A2 binding site form stable complexes with class I major histocompatibility complex molecules.

D. Wiley, M. Bouvier, 1996, Proceedings of the National Academy of Sciences of the United States of America.

A tricyclic ring system replaces the variable regions of peptides presented by three alleles of human MHC class I molecules.

S. Schreiber, D. Wiley, D. Garboczi, 1995, Chemistry & biology.

Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1.

D. Wiley, S. J. Park, S. Sadegh-Nasseri, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Amino acid sequences of haemagglutinins of influenza viruses of the H3 subtype isolated from horses.

J. Skehel, D. Wiley, R. Daniels, 1985, The Journal of general virology.

Crystallization and x-ray diffraction studies on the haemagglutinin glycoprotein from the membrane of influenza virus.

J. Skehel, D. Wiley, 1977, Journal of molecular biology.

MHC gene in cytomegalovirus

D. Wiley, 1988, Nature.

A disulfide‐linked natural killer cell receptor dimer has higher affinity for HLA‐C than wild‐type monomer

Eric O Long, D. Wiley, Q. Fan, 2000, European journal of immunology.

Three-dimensional structures at 5.5 A resolution and regulatory processes in aspartate transcarbamylase from E. coli.

W. Lipscomb, D. Wiley, B. Edwards, 1974, Journal of supramolecular structure.

Aqueous Central Cavity in Aspartate Transcarbamylase from Escherichia coli

W. Lipscomb, D. Wiley, P. Bethge, 1973, Science.

Antigenic and amino acid sequence analysis of the variants of H1N1 influenza virus in 1986.

J. Skehel, D. Wiley, A. Douglas, 1987, Bulletin of the World Health Organization.

The structure of acumycin

D. Wiley, J. Finer-Moore, J. Clardy, 1981 .

Evidence from studies with a cross-linking reagent that the haemagglutinin of influenza virus is a trimer.

J. Skehel, D. Wiley, M. Waterfield, 1977, Virology.

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

Dean R. Madden, Don C. Wiley, D. Wiley, 1992, Cell.

Structure of a human natural killer cell inhibitory receptor.

D. Wiley, L. Mosyak, D. Garboczi, 1999, Transplantation proceedings.

A system for collection and on-line integration of X-ray diffraction data from a multiwire area detector

S. Harrison, D. Wiley, P. Metcalf, 1987 .

CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.

J. J. Rosa, D. Wiley, S. R. Pollard, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragment

S. Harrison, D. Wiley, K. Arnett, 2004 .

Gamblin Hemagglutinin The Structure and Receptor Binding Properties of the 1918 Influenza

J. Skehel, D. Wiley, S. Gamblin, 2012 .

Targets for the Design of Antiviral Agents: Targets in Orthomyxoviruses

J. Skehel, D. Wiley, 1984 .

Deacylation of the hemagglutinin of influenza A/Aichi/2/68 has no effect on membrane fusion properties.

J. Skehel, D. Wiley, D. Steinhauer, 1991, Virology.

Preliminary Studies of the Membrane-Associated Portion of the Hemagglutinin

J. Skehel, D. Wiley, 1978 .

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide.

D. Wiley, L. Stern, 1992, Cell.

Antigenic and amino acid sequence analyses of influenza viruses of the H1N1 subtype isolated between 1982 and 1984.

J. Skehel, D. Wiley, A. Douglas, 1985, Bulletin of the World Health Organization.

Studies of the Hong Kong Influenza Hemagglutinin

J. Skehel, D. Wiley, 1985 .

Importance of peptide amino and carboxyl termini to the stability of MHC class I molecules.

D. Wiley, M. Bouvier, D C Wiley, 1994, Science.

The structure of aspartate transcarbamylase, I. A molecular twofold axis in the complex with cytidine triphosphate.

T. Steitz, W. Lipscomb, D. Wiley, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Aspartate transcarbamoylase from Escherichia coli: electron density at 5.5 A resolution.

W. Lipscomb, D. Wiley, B. Edwards, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Structure of an unliganded simian immunodeficiency virus gp120 core

Don C. Wiley, Bing Chen, Haiyun Gong, 2005, Nature.

Atomic structure of the ectodomain from HIV-1 gp41

S. Harrison, W. Weissenhorn, J. Skehel, 1997, Nature.

Ligand recognition by influenza virus. The binding of bivalent sialosides.

J. Knowles, J. Skehel, D. Wiley, 1991, The Journal of biological chemistry.

Variant specific glycoprotein of Trypanosoma brucei consists of two domains each having an independently conserved pattern of cysteine residues.

D. Wiley, M. Carrington, M. Turner, 1991, Journal of molecular biology.

Structure of a human insulin peptide–HLA-DQ8 complex and susceptibility to type 1 diabetes

Don C. Wiley, D. Wiley, K. Wucherpfennig, 2001, Nature Immunology.

Zinc-dependent dimers observed in crystals of human endostatin.

R. Timpl, D. Wiley, J. Folkman, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1–HLA-Cw4 complex

Eric O Long, D. Wiley, Q. Fan, 2001, Nature Immunology.

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

M. A. Saper, D. Wiley, J. Strominger, 1987, Nature.

Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin

J. Skehel, D. Wiley, D. Steinhauer, 1995, Journal of virology.

Fusion mutants of the influenza virus hemagglutinin glycoprotein

D. Wiley, A. Hay, R. Daniels, 1985, Cell.

Antigenic peptide binding by class I and class II histocompatibility proteins.

D. Wiley, L. Stern, D C Wiley, 1994, Behring Institute Mitteilungen.

A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody.

I. Wilson, J. Skehel, D. Wiley, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV.

J. Skehel, D. Wiley, G. Smith, 1989, Virology.

Synthesis and configuration of cis-2,6-dimethyl-1,4-cyclohexanedione, r-2, c-6-dimethyl-c-4-hydroxycyclohexanone and two related diols

D. Wiley, T. Giants, R. Krikorian, 1972 .

Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1.

D. Wiley, J. Strominger, R. Urban, 1994, Science.

Proton nuclear magnetic resonance studies of the binding of sialosides to intact influenza virus.

J. Skehel, D. Wiley, N. Sauter, 1992, Virology.

T Cell Receptor–MHC Interactions up Close

D. Wiley, J. Hennecke, 2001, Cell.

The structure and role of the carbohydrate moieties of influenza virus haemagglutinin.

I. Wilson, J. Skehel, D. Wiley, 1983, Biochemical Society transactions.

Temperature dependence of fusion by sendai virus.

J. Skehel, D. Wiley, S. Wharton, 2000, Virology.

Chapter 20 Viral membranes

J. Skehel, D. Wiley, D. Steinhauer, 1998 .

Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors

Eric O Long, D. Wiley, L. Mosyak, 1997, Nature.

Two variant surface glycoproteins of Trypanosoma Brucei of different sequence classes have similar 6 Å resolution X-ray structures

D. Wiley, M. Turner, D. Freymann, 1987, Nature.

A structural motif in the variant surface glycoproteins of Trypanosoma brucei

D. Wiley, M. Carrington, M. Turner, 1993, Nature.

Comparative analyses of the specificities of anti-influenza hemagglutinin antibodies in human sera

J. Skehel, D. Wiley, M. L. Wang, 1986, Journal of virology.

Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein

Don C. Wiley, D. Wiley, K. Wucherpfennig, 1998, The Journal of experimental medicine.

Complexed with a Peptide from Human Myelin Basic Protein

Don C. Wiley, D. Wiley, K. Wucherpfennig, 1998 .

Covalent HLA-B27/peptide complex induced by specific recognition of an aziridine mimic of arginine.

S. Schreiber, D. Wiley, William Arbuthnot Sir Lane, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein.

L Gauthier, D. Wiley, J. Strominger, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401)

Don C. Wiley, D. Wiley, J. Hennecke, 2002, The Journal of experimental medicine.

Structure of a covalently stabilized complex of a human αβ T‐cell receptor, influenza HA peptide and MHC class II molecule, HLA‐DR1

D. Wiley, A. Carfi, J. Hennecke, 2000, The EMBO journal.

X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.

D. Zaller, D. Wiley, A. Dessen, 1997, Immunity.

Three-dimensional structure of a peptide extending from one end of a class I MHC binding site

Edward J. Collins, Don C. Wiley, D. Wiley, 1994, Nature.

Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen

Don C. Wiley, D. Wiley, J. Strominger, 1994, Nature.

Antigenic peptide binding by class I and class II histocompatibility proteins.

D. Wiley, L. Stern, D C Wiley, 1994, Structure.

Identification of self peptides bound to purified HLA-B27

D. R. Madden, D. Wiley, William Arbuthnot Sir Lane, 1991, Nature.

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

D. R. Madden, D. Wiley, J. Strominger, 1991, Nature.

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

D. Wiley, P. Bjorkman, T. Jardetzky, 1988, Nature.

Structure of unliganded HSV gD reveals a mechanism for receptor‐mediated activation of virus entry

D. Wiley, R. Eisenberg, G. Cohen, 2005, The EMBO journal.

Structural basis for membrane fusion by enveloped viruses.

S. Harrison, W. Weissenhorn, J. Skehel, 1999, Molecular membrane biology.

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

Rachelle Gaudet, D. Wiley, R. Gaudet, 2001, The EMBO journal.

Noble metals strip peptides from class II MHC proteins

Timothy J Mitchison, D. Wiley, B. DeDecker, 2006, Nature chemical biology.

Potential Nectin-1 Binding Site on Herpes Simplex Virus Glycoprotein D

D. Wiley, R. Eisenberg, G. Cohen, 2005, Journal of Virology.

Reconstitution by MHC-restricted peptides of HLA-A2 heavy chain with β2-microglobulin, in vitro

K. Parker, D. Wiley, M. L. Silver, 1991, Nature.

Data collection from very thin HLA crystals using synchrotron radiation.

D. Wiley, P. Bjorkman, W. Bennett, 1989, Basic life sciences.

Evidence that multiple residues on both the α-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor

D. Wiley, J. Bluestone, S. Nathenson, 1988, Cell.

Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.

W. Weissenhorn, J. Skehel, D. Wiley, 1998, Molecular cell.

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

William S. Lane, Don C. Wiley, D. Wiley, 1992, Nature.

The ectodomain of HIV‐1 env subunit gp41 forms a soluble, alpha‐helical, rod‐like oligomer in the absence of gp120 and the N‐terminal fusion peptide.

P. Earl, B. Moss, W. Weissenhorn, 1996, The EMBO journal.

Peptide recognition by two HLA-A2/Tax11-19-specific T cell clones in relationship to their MHC/peptide/TCR crystal structures.

D. Wiley, U. Utz, D. Garboczi, 1999, Journal of immunology.

The Crystal Structure of a Pyrrolinone−Peptide Hybrid Ligand Bound to the Human Class II MHC Protein HLA-DR1

D. Wiley, Kon-Ho Lee, D. Bolin, 2000 .

Structure of a trimeric domain of the MHC class II‐associated chaperonin and targeting protein Ii

D. Wiley, A. Jasanoff, G. Wagner, 1998, The EMBO journal.

Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by Tax Peptide/Hla-A2–Specific T Cell Receptors

Brian M. Baker, Don C. Wiley, D. Wiley, 2001, The Journal of experimental medicine.

Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.

D. Wiley, U. Utz, D. Garboczi, 1996, Journal of immunology.

Comparison of orthorhombic and monoclinic crystal structures of HLA-A2.

D. Wiley, J. Strominger, P. Bjorkman, 1989, Cold Spring Harbor symposia on quantitative biology.

Structural, biochemical, and biophysical studies of HLA-A2/altered peptide ligands binding to viral-peptide-specific human T-cell receptors.

B M Baker, D. Wiley, D. Garboczi, 1999, Cold Spring Harbor symposia on quantitative biology.

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

D. Wiley, H. Ploegh, D. Tortorella, 2001, Proceedings of the National Academy of Sciences of the United States of America.

One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules.

D. Wiley, A. Jasanoff, G. Wagner, 1999, Immunity.

Crystal Structures of Two Closely Related but Antigenically Distinct HLA-A2/Melanocyte-Melanoma Tumor-Antigen Peptide Complexes1

M. Karplus, D. Wiley, P. Romero, 2001, The Journal of Immunology.

Tumor-Antigen Peptide Complexes HLA-A 2 / Melanocyte-Melanoma Antigenically Distinct Crystal Structures of Two Closely Related but C

M. Karplus, D. Wiley, P. Romero, 2001 .

Protein, DNA, and virus crystallography with a focused imaging proportional counter.

P Metcalf, S. Harrison, D. Wiley, 1986, Science.

Structure of Human Histocompatibility Leukocyte Antigen (Hla)-Cw4, a Ligand for the Kir2d Natural Killer Cell Inhibitory Receptor

Don C. Wiley, D. Wiley, Q. Fan, 1999, The Journal of experimental medicine.

Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

D. Wiley, B. Baker, W. Biddison, 2000, Immunity.

Crystal Structures of Hla-a*0201 Complexed with Antigenic Peptides with Either the Amino-or Carboxyl-terminal Group Substituted by a Methyl Group

D. Wiley, Kathrine J. Smith, Hwai-Chen Guo, 2022 .

Five viral peptide-HLA-A2 co-crystals. Simultaneous space group determination and X-ray data collection.

D. Wiley, D. Garboczi, D. Madden, 1994, Journal of Molecular Biology.

Peptide-N-Terminal Binding Site Complex with an Empty Conserved HLA-A * 0201 / Octameric Tax Peptide The Structure and Stability of an Biddison

D. Wiley, B. Baker, P. Ghosh, 2000 .

Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains.

I. Wilson, J. Skehel, D. Wiley, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Peptide binding to major histocompatibility complex molecules

D. Wiley, D. Madden, 1992, Current Biology.

Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements

Stuart L. Schreiber, Don C. Wiley, Winfried Weissenhorn, 1999, Nature Structural Biology.

Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli.

J. L. Crawford, J L Crawford, J E Ladner, 1982, Journal of molecular biology.

Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus.

D. Wiley, C. Smith, A. Carfi, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Crystals of a fragment of influenza haemagglutinin in the low pH induced conformation.

J. Skehel, D. Wiley, R. Ruigrok, 1994, Journal of Molecular Biology.

Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity.

J. Skehel, D. Wiley, D. Steinhauer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

6 Å-Resolution X-ray structure of a variable surface glycoprotein from Trypanosoma brucei

D. Wiley, M. Turner, D. Freymann, 1984, Nature.

Membrane fusion by surrogate receptor-bound influenza haemagglutinin.

J. Skehel, D. Wiley, L. Calder, 1999, Virology.

The central structural feature of the membrane fusion protein subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil.

W. Weissenhorn, J. Skehel, D. Wiley, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity

J. Skehel, D. Wiley, B. Ely, 1992, Cell.

Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro.

S. Harrison, W. Weissenhorn, D. Wiley, 1996, European journal of biochemistry.

Structure-Based Analysis of the Herpes Simplex Virus Glycoprotein D Binding Site Present on Herpesvirus Entry Mediator HveA (HVEM)

D. Wiley, R. Eisenberg, G. Cohen, 2002, Journal of Virology.

Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus

J. Skehel, D. Wiley, Chi‐Huey Wong, 1998, Nature.

Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus

J. Skehel, D. Wiley, Chi‐Huey Wong, 1998, Nature.

X‐ray crystallographic determination of the structure of the influenza C virus haemagglutinin‐esterase‐fusion glycoprotein

J. Skehel, D. Wiley, Chi‐Huey Wong, 1999, Acta crystallographica. Section D, Biological crystallography.

Influenza viruses and cell membranes.

J. Skehel, D. Wiley, 1995, American journal of respiratory and critical care medicine.

Antigenicity of the Influenza Haemagglutinin Membrane Glycoprotein

J. Skehel, D. Wiley, 1987 .

Crystallographic Determination of Symmetry of Aspartate Transcarbamylase

W. Lipscomb, D. Wiley, 1968, Nature.

Antigenic and amino acid sequence variations in the haemagglutinins of type A influenza viruses recently isolated from human subjects.

J. Skehel, D. Wiley, A. Douglas, 1983, Bulletin of the World Health Organization.

αβ T Cell Receptor Ligand-Specific Oligomerization Revisited

Brian M. Baker, Don C. Wiley, D. Wiley, 2001 .

Herpes simplex virus glycoprotein D bound to the human receptor HveA.

D. Wiley, R. Eisenberg, G. Cohen, 2001, Molecular cell.

Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.

S. Harrison, D. Wiley, K. Arnett, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Structure-Based Mutagenesis of Herpes Simplex Virus Glycoprotein D Defines Three Critical Regions at the gD-HveA/HVEM Binding Interface

D. Wiley, R. Eisenberg, G. Cohen, 2003, Journal of Virology.

Studies of influenza haemagglutinin-mediated membrane fusion.

J. Skehel, D. Wiley, S. Wharton, 1986, Virology.

Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion.

J. Skehel, D. Wiley, D. Steinhauer, 1997, Virology.

Studies on influenza haemagglutinin fusion peptide mutants generated by reverse genetics

J. Skehel, D. Wiley, D. Steinhauer, 2001, The EMBO journal.

The structure of a membrane fusion mutant of the influenza virus haemagglutinin.

J. Skehel, D. Wiley, W. Weis, 1990, The EMBO journal.

Three-dimensional crystals of the lipid-enveloped Semliki Forest virus.

D. Wiley, C. von Bonsdorff, 1978, Journal of Molecular Biology.

Conformational aspects of the acid-induced fusion mechanism of influenza virus hemagglutinin. Circular dichroism and fluorescence studies.

J. Skehel, D. Wiley, W. Weis, 1988, The Journal of biological chemistry.

Identification of domain boundaries within the N‐termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin‐mediated increase in peptide loading of MHC class I

D. Wiley, E. Procko, R. Gaudet, 2005, Immunology and cell biology.

Crystallization of amino-terminal domains and domain fragments of variant surface glycoproteins from Trypanosoma brucei brucei.

D. Wiley, M. Turner, J. Down, 1988, The Journal of biological chemistry.

Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli.

W. Weissenhorn, J. Skehel, D. Wiley, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Evasion of host defenses: group report.

A. Tomasz, J. Skehel, D. Wiley, 1980 .

Expression, Purification, and Characterization of gp160e, the Soluble, Trimeric Ectodomain of the Simian Immunodeficiency Virus Envelope Glycoprotein, gp160*

S. Harrison, E. Reinherz, J. Skehel, 2000, The Journal of Biological Chemistry.

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

S. Harrison, J. Skehel, D. Wiley, 2005, Structure.

The structure of the influenza virus haemagglutinin glycoprotein at 3 Ã resolution

Ian A. Wilson, Don C. Wiley, I. Wilson, 1981 .

Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA.

D. Wiley, R. Eisenberg, G. Cohen, 2002, Acta crystallographica. Section D, Biological crystallography.

A Chimeric Protein of Simian Immunodeficiency Virus Envelope Glycoprotein gp140 and Escherichia coli Aspartate Transcarbamoylase

S. Harrison, E. Reinherz, J. Skehel, 2004, Journal of Virology.

alpha beta T cell receptor ligand-specific oligomerization revisited.

D. Wiley, B. Baker, 2001, Immunity.

CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX

D. Wiley, B. Baker, P. Ghosh, 2000 .

Crystallization and preliminary X‐ray diffraction studies of the influenza C virus glycoprotein

J. Skehel, D. Wiley, J. Newman, 1996, Acta Crystallographica Section D: Biological Crystallography.

Changes in the conformation of inf the pH optimum of virus-mediated (virus glycoprotein/lipid binding/detergent binding)

I. Wilson, J. Skehel, D. Wiley, 2016 .

Studies on the structure of the haemagglutinin.

J. Skehel, D. Wiley, M. Waterfield, 1980, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 1996. 384: 134-141.

D. Wiley, U. Utz, D. Garboczi, 2010, Journal of immunology.

Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein

D. Wiley, K. Wucherpfennig, J. Pyrdol, 1998, The Journal of experimental medicine.

Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.

D. Wiley, J. Strominger, M. Saper, 2005 .

Studies on the Structure and Activities of Influenza Virus Haemagglutinin

I. Wilson, J. Skehel, D. Wiley, 1984 .

Ligand Recognition by Influenza Virus

J. Skehel, D. Wiley, L. Peter, 1991 .

Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.

J. Skehel, D. Wiley, N. Sauter, 1994, Biochemistry.

Recognition at Membrane Surfaces Influenza HA and Human HLA

D. Wiley, 1990 .