J. Culp

发表

The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations.

K. Murthy, E. Winborne, M. Minnich, 1994 .

Immunohistochemical localization of PDE10A in the rat brain

Jerry Lanfear, J. Culp, F. Menniti, 2003, Brain Research.

Screening Orphan Receptors for Native Ligands

J. Culp, J. Chambers, H. Sarau, 2019, G Protein-Coupled Receptors.

The active-site and amino-terminal amino acid sequence of bovine intestinal alkaline phosphatase.

J. Culp, M. Hermodson, L. Butler, 1985, Biochimica et biophysica acta.

Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK).

J. Pandit, J. Culp, K. Parris, 2017, Journal of medicinal chemistry.

Amino acid sequence of the active site peptide of bovine intestinal 5'-nucleotide phosphodiesterase and identification of the active site residue as threonine.

J. Culp, M. Hermodson, L. Butler, 1985, The Journal of biological chemistry.

Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation

Graham M. West, J. Culp, E. Carpenter, 2019, eLife.

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.

J. Culp, C. Smith, R. Ricciardi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis for the transport mechanism of the human glutamine transporter SLC1A5 (ASCT2)

Graham M. West, J. Culp, E. Carpenter, 2019, bioRxiv.

Phosphorylation of serine residue 89 of human adenovirus E1A proteins is responsible for their characteristic electrophoretic mobility shifts, and its mutation affects biological function

J. Culp, C. Debouck, C. Smith, 1989 .

Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4.

J. Culp, M. Rosenberg, R. Sweet, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.

J. Culp, B. Chance, R. Ricciardi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis.

R. DesJarlais, K. Murthy, E. Winborne, 1993, Biochemistry.

Kinetic and mutational analysis of human immunodeficiency virus type 1 reverse transcriptase inhibition by inophyllums, a novel class of non-nucleoside inhibitors.

J. Culp, C. Debouck, R. Hertzberg, 1994, The Journal of biological chemistry.

Unique fold and active site in cytomegalovirus protease

J. Culp, A. Dilella, S. Abdel-Meguid, 1996, Nature.

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Ing-Kae Wang, Xiayang Qiu, Dennis E Danley, 2007, Nature Structural &Molecular Biology.

Distribution of phosphodiesterase I in normal human tissues.

J. Culp, T. Ulbright, M. Hodes, 1987, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Alkaline phosphatase and 5'-nucleotide phosphodiesterase from bovine intestine are cross-reactive.

J. Culp, L. Butler, 1985, Biochemistry.

The relationship of alkaline phosphatase, CaATPase, and phytase.

S. Williams, J. Culp, L. Butler, 1985, Archives of biochemistry and biophysics.

Phosphorylated threonine as the covalent intermediate in snake venom phosphodiesterase.

J. Culp, L. Butler, 1986, Archives of biochemistry and biophysics.

tRNA Modification by S-Adenosylmethionine:tRNA Ribosyltransferase-Isomerase

J. Culp, S. V. Van Lanen, S. D. Kinzie, 2003, The Journal of Biological Chemistry.

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.

D W Rodgers, S. Harrison, J. Culp, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of varicella-zoster virus protease.

J. Culp, C. Debouck, S. Abdel-Meguid, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

Xiayang Qiu, Dennis E Danley, S. Shenolikar, 2007, Nature Structural &Molecular Biology.

Characterization of HIV‐1 p24 self‐association using analytical affinity chromatography

J. Culp, C. Debouck, I. Chaiken, 1992, Proteins.

Phosphorylation of Serine Residue 89 of Human Adenovirus E1A Proteins Is Responsible for Their Characteristic Electrophoretic Mobility Shifts, and Its Mutation Affects Biological Function

J. Culp, C. Debouck, C. Smith, 1989, Journal of virology.

Probability Analysis of Variational Crystallization and Its Application to gp120, The Exterior Envelope Glycoprotein of Type 1 Human Immunodeficiency Virus (HIV-1)*

J. Sodroski, R. Wyatt, J. Culp, 1999, The Journal of Biological Chemistry.

Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease.

M. Minnich, J. Culp, C. Debouck, 1991, Biochemistry.

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

D. Lin, Hong Wang, J. Culp, 2017, PloS one.

Seed ticks.

J. Culp, 1987, American family physician.

Human immunodeficiency virus-1 protease. 1. Initial velocity studies and kinetic characterization of reaction intermediates by 18O isotope exchange.

S. Carr, M. Minnich, J. Culp, 1991, Biochemistry.

Use of protein unfolding studies to determine the conformational and dimeric stabilities of HIV-1 and SIV proteases.

M. Minnich, J. Culp, C. Debouck, 1992, Biochemistry.

Effect of human immunodeficiency virus gp120 glycoprotein on the association of the protein tyrosine kinase p56lck with CD4 in human T lymphocytes.

S. Kassis, J. Culp, A. Truneh, 1991, The Journal of biological chemistry.

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

David G Myszka, Dennis E Danley, R. Fletterick, 2002, Chemistry & biology.

Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors.

Baoguang Zhao, E. Winborne, M. Minnich, 1993, Biochemistry.