P. Acklin

发表

Comparison of topological descriptors for similarity-based virtual screening using multiple bioactive reference structures.

P. Willett, J. Hert, E. Jacoby, 2004, Organic & biomolecular chemistry.

Enhancing the effectiveness of similarity-based virtual screening using nearest-neighbor information.

P. Willett, J. Hert, E. Jacoby, 2005, Journal of medicinal chemistry.

Prioritization of high throughput screening data of compound mixtures using molecular similarity

M. Glick, J. Davies, P. Acklin, 2003 .

Finding more needles in the haystack: A simple and efficient method for improving high-throughput docking results.

Anthony E. Klon, M. Glick, J. Davies, 2004, Journal of medicinal chemistry.

N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1999, Bioorganic & medicinal chemistry letters.

5-Aminomethylquinoxaline-2,3-diones. Part II: N-aryl derivatives as novel NMDA/glycine and AMPA antagonists.

P. Acklin, Y. Auberson, M. Biollaz, 1998, Bioorganic & medicinal chemistry letters.

Sequential Superparamagnetic Clustering for Unbiased Classification of High‐Dimensional Chemical Data.

Ruedi Stoop, Pierre Acklin, Edgar Jacoby, 2004 .

A highly stereoselective in vitro cyclization of dolabellatriene diterpenes into novel dolastadienes

P. Acklin, L. Jenny, Hans‐Jürg Borschberg, 1996 .

5-Aminomethylquinoxaline-2,3-diones, Part III: Arylamide derivatives as highly potent and selective glycine-site NMDA receptor antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1998, Bioorganic & medicinal chemistry letters.

Oxiranyllithium reagents: Generation from organotin precursors, addition to aldehydes and ketones, and dimerization to α,α′-dialkoxyolefins

P. Acklin, P. Lohse, A. Pfaltz, 1991 .

4-3,5-BIS(2-HYDROXYPHENYL)-1,2,4-TRIAZOL-1-YL-BENZOIC ACID : A NOVEL EFFICIENT AND SELECTIVE IRON(III) COMPLEXING AGENT

P. Acklin, B. Faller, U. Heinz, 1999 .

Development of tridentate iron chelators: from desferrithiocin to ICL670.

P. Acklin, D. Alberti, H. Nick, 2003, Current medicinal chemistry.

ICL670A: preclinical profile.

P. Acklin, B. Faller, Helmut Thomas, 2002, Advances in experimental medicine and biology.

Similarity Metrics for Ligands Reflecting the Similarity of the Target Proteins

Pierre Acklin, Edgar Jacoby, Ansgar Schuffenhauer, 2003, J. Chem. Inf. Comput. Sci..

Sequential Superparamagnetic Clustering for Unbiased Classification of High-Dimensional Chemical Data

Ruedi Stoop, Pierre Acklin, Edgar Jacoby, 2004, J. Chem. Inf. Model..

5‐Aminomethylquinoxaline‐2,3‐diones. Part 3. Arylamide Derivatives as Highly Potent and Selective Glycine‐Site NMDA Receptor Antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1998 .

New Methods for Ligand-Based Virtual Screening: Use of Data Fusion and Machine Learning to Enhance the Effectiveness of Similarity Searching

Jérôme Hert, Peter Willett, David J Wilton, 2006, J. Chem. Inf. Model..

Comparison of Fingerprint-Based Methods for Virtual Screening Using Multiple Bioactive Reference Structures

Jérôme Hert, Peter Willett, Pierre Acklin, 2004, J. Chem. Inf. Model..

Enrichment of Extremely Noisy High-Throughput Screening Data Using a Naïve Bayes Classifier

Meir Glick, Pierre Acklin, Anthony E. Klon, 2004, Journal of biomolecular screening.

Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection.

Peter Meier, Pierre Acklin, Kamal Azzaoui, 2005, Current topics in medicinal chemistry.

New Scoring Functions for Virtual Screening from Molecular Dynamics Simulations with a Quantum‐Refined Force‐Field (QRFF‐MD). Application to Cyclin‐Dependent Kinase 2.

Alessandro Curioni, Eric Vangrevelinghe, Tiziana Mordasini, 2006 .