T. Mironenko

发表

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Gurpreet W. Tang, Karl J. Dykema, M. Stratton, 2009, Nature.

Systematic identification of genomic markers of drug sensitivity in cancer cells

S. Ramaswamy, M. Stratton, P. Futreal, 2012, Nature.

A Landscape of Pharmacogenomic Interactions in Cancer

Emanuel J. V. Gonçalves, M. Stratton, G. Bignell, 2016, Cell.

Patterns of somatic mutation in human cancer genomes

E. Birney, A. Nicholson, M. Stratton, 2007, Nature.

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

Andrew Menzies, Sarah Edkins, Sara Widaa, 2009, Nature Genetics.

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

Emanuel J. V. Gonçalves, A. Leach, F. Iorio, 2020, Molecular systems biology.

Resource A Landscape of Pharmacogenomic Interactions in Cancer Graphical Abstract Highlights

Emanuel J. V. Gonçalves, M. Stratton, G. Bignell, 2016 .

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.

Andrew Menzies, Keiran Raine, Sarah Edkins, 2007, American journal of human genetics.

Patterns of somatic mutation in human cancer genomes

E. Birney, A. Nicholson, M. Stratton, 2007, Nature.

Somatic mutations of the histone H3K27 demethylase, UTX, in human cancer

Bin Tean Teh, Chai Yin Kok, Andrew Menzies, 2009, Nature Genetics.

X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment

Andrew Menzies, Sarah Edkins, Sara Widaa, 2008, Nature Genetics.

The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A.

P. Leadlay, T. Mironenko, S. Haydock, 2006, Chemistry & biology.

Increasing the efficiency of heterologous promoters in actinomycetes.

Christine J. Martin, P. Leadlay, T. Mironenko, 2002, Journal of molecular microbiology and biotechnology.

Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.

Hui Hong, P. Leadlay, Z. Deng, 2007, Chemistry & biology.

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338

Markiyan Samborskyy, P. Leadlay, T. Mironenko, 2007, Nature Biotechnology.

The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.

T. Mironenko, S. Haydock, D. Spiteller, 2005, Organic & biomolecular chemistry.

The putative elaiophylin biosynthetic gene cluster in Streptomyces sp. DSM4137 is adjacent to genes encoding adenosylcobalamin-dependent methylmalonyl CoA mutase and to genes for synthesis of cobalamin.

P. Leadlay, T. Mironenko, S. Haydock, 2004, Journal of biotechnology.

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

J. Gécz, M. Stratton, P. Futreal, 2007, Nature Genetics.

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

Richard Lugg, Andrew Menzies, Michael R. Stratton, 2006, Molecular Cancer Therapeutics.

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

Andrew R. Leach, Francesco Iorio, Clare Pacini, 2020, bioRxiv.

LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition

M. Stratton, T. Santarius, S. Edkins, 2009, British Journal of Cancer.

Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.

P. Leadlay, T. Mironenko, S. Haydock, 2004, Chemistry & biology.

Effective drug combinations in breast, colon and pancreatic cancer cells

S. Barthorpe, T. Mironenko, M. Garnett, 2022, Nature.

Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing’s Sarcoma

M. Stratton, U. McDermott, S. Barthorpe, 2015, PloS one.

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly.

K. Friend, M. Shaw, J. Gécz, 2007, American journal of human genetics.

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

J. Gécz, M. Stratton, P. Futreal, 2006, American journal of human genetics.

Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.

P. Leadlay, T. Mironenko, S. Haydock, 2005, Microbiology.

Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.

Markiyan Samborskyy, Hui Hong, P. Leadlay, 2006, Microbiology.

Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations

Jerome T. Mettetal, S. Barthorpe, T. Mironenko, 2024, Cancer discovery.