D. Kristensen

发表

An accurate, sensitive, and scalable method to identify functional sites in protein structures.

L. Kavraki, O. Lichtarge, H. Yao, 2003, Journal of molecular biology.

Structural clusters of evolutionary trace residues are statistically significant and common in proteins.

O. Lichtarge, H. Yao, D. Kristensen, 2002, Journal of molecular biology.

Aniline Is Rapidly Converted Into Paracetamol Impairing Male Reproductive Development.

K. Kristiansen, B. Jensen, D. Kristensen, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Evolutionarily Conserved Orthologous Families in Phages Are Relatively Rare in Their Prokaryotic Hosts

A. Mushegian, D. Kristensen, X. Cai, 2011, Journal of bacteriology.

Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes

E. Koonin, Y. Wolf, D. Kristensen, 2014, BMC Biology.

Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.

F. Quiocho, D. Kristensen, Jianpeng Ma, 2005, Biochemistry.

Recurrent use of evolutionary importance for functional annotation of proteins based on local structural similarity

Olivier Lichtarge, Marek Kimmel, L. Kavraki, 2006, Protein science : a publication of the Protein Society.

Orthologous Gene Clusters and Taxon Signature Genes for Viruses of Prokaryotes

Peer Bork, Arcady R. Mushegian, Eugene V. Koonin, 2012, Journal of bacteriology.

Classification and quantification of bacteriophage taxa in human gut metagenomes

Peer Bork, Shinichi Sunagawa, Eugene V Koonin, 2014, The ISME Journal.

New dimensions of the virus world discovered through metagenomics.

Eugene V Koonin, David M Kristensen, Valerian V Dolja, 2010, Trends in microbiology.

De-Orphaning the Structural Proteome through Reciprocal Comparison of Evolutionarily Important Structural Features

Andreas Martin Lisewski, Olivier Lichtarge, David M. Kristensen, 2008, PloS one.

Manuscript accepted to special issue of Protein Science relating to function annotation work shown at the 2005 ISMB conference)

L. Kavraki, A. M. Lisewski, O. Lichtarge, 2006 .

Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3β-HSD inhibition.

D. Kristensen, B. Styrishave, Cecilie Hurup Munkboel, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Paracetamol use during pregnancy — a call for precautionary action

S. Swan, N. Skakkebaek, D. Kristensen, 2021, Nature Reviews Endocrinology.

EDC IMPACT: Is exposure during pregnancy to acetaminophen/paracetamol disrupting female reproductive development?

D. Kristensen, B. Jégou, S. Mazaud-Guittot, 2017, Endocrine connections.

ATP sensitive potassium (KATP) channel inhibition: A promising new drug target for migraine

J. Olesen, D. Kristensen, I. Jansen-Olesen, 2020, Cephalalgia : an international journal of headache.

Functional gene networks reveal distinct mechanisms segregating in migraine families

J. Olesen, D. Kristensen, T. Hansen, 2020, Brain : a journal of neurology.

Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.

H. Leffers, N. Skakkebaek, D. Kristensen, 2008, Human reproduction.

Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract.

H. Leffers, N. Skakkebaek, N. Jørgensen, 2010, Human reproduction.

Reconstruction of the evolution of microbial defense systems

E. Koonin, Y. Wolf, K. Makarova, 2017, BMC Evolutionary Biology.

Evolutionary switches between two serine codon sets are driven by selection

E. Koonin, D. Kristensen, S. Shabalina, 2016, Proceedings of the National Academy of Sciences.

Indomethacin Treatment Prevents High Fat Diet-induced Obesity and Insulin Resistance but Not Glucose Intolerance in C57BL/6J Mice*

K. Kristiansen, L. Madsen, B. Hudson, 2014, The Journal of Biological Chemistry.

Assessment of the analgesic dipyrone as a possible (anti)androgenic endocrine disruptor.

D. Kristensen, B. van Ravenzwaay, Marcella Tapias Passoni, 2017, Toxicology letters.

Prenatal exposure to perfluoroalkyl substances and anogenital distance at 3 months of age in a Danish mother-child cohort.

L. Priskorn, T. K. Jensen, T. H. Lassen, 2017, Reproductive toxicology.

Mammary alveolar epithelial cells convert to brown adipocytes in post‐lactating mice

K. Kristiansen, D. Kristensen, S. Kajimura, 2017, Journal of cellular physiology.

New dimensions of the virus world discovered through metagenomics.

E. Koonin, A. Mushegian, D. Kristensen, 2010, Trends in microbiology.

Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

D. Kristensen, I. Jansen-Olesen, D. Klærke, 2022, The Journal of Headache and Pain.

Characterisation and localisation of the endocannabinoid system components in the adult human testis

N. Skakkebaek, D. Kristensen, E. Rajpert-De Meyts, 2019, Scientific Reports.

Ex vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in Rodents.

D. Kristensen, I. Jansen-Olesen, S. L. Christensen, 2022, Journal of visualized experiments : JoVE.

Targeting CGRP via receptor antagonism and antibody neutralisation in two distinct rodent models of migraine-like pain

J. Olesen, D. Kristensen, G. Munro, 2019, Cephalalgia : an international journal of headache.

The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial

D. Kristensen, G. Greisen, C. Vedel, 2022, PloS one.

Extreme secondary sexual dimorphism in the genus Florarctus (Heterotardigrada: Halechiniscidae)

D. Kristensen, R. Kristensen, P. Gąsiorek, 2021, Marine Biodiversity.

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

Søren Brunak, Jorma Toppari, Julie Boberg, 2011, Human reproduction.

Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’

S. Swan, N. Skakkebaek, D. Kristensen, 2021, Nature Reviews Endocrinology.

Intrauterine exposure to drugs and reproduction—still reasons for concern!

D. Kristensen, S. Mazaud-Guittot, Rikke Stausholm, 2019, Current Opinion in Endocrine and Metabolic Research.

Prenatal exposures to paracetamol / acetaminophen and precursor aniline impair 1 masculinisation of male brain and behaviour 2 3

S. Brunak, B. Jensen, T. K. Jensen, 2017 .

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother–child pairs

J. Toppari, T. K. Jensen, D. Kristensen, 2016, Human reproduction.

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility.

K. Kristiansen, B. Jensen, D. Kristensen, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Reply: analgesic use and its effect on male reproduction

J. Toppari, T. K. Jensen, D. Kristensen, 2011 .

Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring.

D. Kristensen, H. Koch, B. Jégou, 2020, Environment international.

No additive effect of combining sumatriptan and olcegepant in the GTN mouse model of migraine

J. Olesen, D. Kristensen, S. L. Christensen, 2020, Cephalalgia : an international journal of headache.

A low-polynomial algorithm for assembling clusters of orthologous groups from intergenomic symmetric best matches

Lavanya Kannan, Arcady R. Mushegian, Eugene V. Koonin, 2010, Bioinform..

Effect of perfluoroalkyl exposure in pregnancy and infancy on intrauterine and childhood growth and anthropometry. Sub study from COPSAC2010 birth cohort

K. Bønnelykke, H. Bisgaard, D. Kristensen, 2022, EBioMedicine.

CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine

D. Kristensen, J. Chaker, S. Christensen, 2021, Cephalalgia : an international journal of headache.

No central action of CGRP antagonising drugs in the GTN mouse model of migraine

J. Olesen, D. Kristensen, S. L. Christensen, 2020, Cephalalgia : an international journal of headache.

A census of α-helical membrane proteins in double-stranded DNA viruses infecting bacteria and archaea

D. Frishman, E. Koonin, D. Kristensen, 2015, BMC Bioinformatics.

Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

D. Kristensen, T. Hansen, C. Janfelt, 2021, Cephalalgia : an international journal of headache.

Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo

D. Kristensen, B. Jégou, S. Mazaud-Guittot, 2018, Human reproduction.

Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study

T. K. Jensen, S. Swan, D. Kristensen, 2017, Environmental Health.

Origin of pluripotent germ cell tumours: The role of microenvironment during embryonic development

H. Leffers, N. Skakkebaek, D. Kristensen, 2008, Molecular and Cellular Endocrinology.

Testicular dysgenesis syndrome and the origin of carcinoma in situ testis.

H. Leffers, I. A. Olesen, N. Skakkebaek, 2008, International journal of andrology.

Cavity Scaling: Automated Refinement of Cavity-Aware motifs in protein Function Prediction

Lydia E. Kavraki, Olivier Lichtarge, Marek Kimmel, 2007, J. Bioinform. Comput. Biol..

Analysis of SOX2 expression in developing human testis and germ cell neoplasia.

H. Leffers, D. Kristensen, N. Hanley, 2010, The International journal of developmental biology.

A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples

H. Leffers, I. A. Olesen, D. Kristensen, 2012, Andrologia.

Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.

D. Kristensen, Christophe Nicolas Nicolaz, B. Jégou, 2013, The Journal of clinical endocrinology and metabolism.

Analgesic use — prevalence, biomonitoring and endocrine and reproductive effects

D. Kristensen, K. Main, B. Jégou, 2016, Nature Reviews Endocrinology.

Computational methods for Gene Orthology inference

Arcady R. Mushegian, Eugene V. Koonin, Yuri I. Wolf, 2011, Briefings Bioinform..

Ibuprofen results in alterations of human fetal testis development

B. Le Bizec, J. Antignac, D. Kristensen, 2017, Scientific Reports.

OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres.

S. Brunak, H. Leffers, N. Skakkebaek, 2010, Molecular human reproduction.

Coupling Between Protein Level Selection and Codon Usage Optimization in the Evolution of Bacteria and Archaea

Eugene V. Koonin, David M. Kristensen, E. Koonin, 2014, mBio.

Cytokine signalling in embryonic stem cells

D. Kristensen, J. Nielsen, M. Kalisz, 2005, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Inter-annual growth of Arctic charr (Salvelinus alpinus, L.) in relation to climate variation

R. K. Larsen, D. Kristensen, T. Jørgensen, 2006, BMC Ecology.

Evolutionary Trace Annotation Server: automated enzyme function prediction in protein structures using 3D templates

Olivier Lichtarge, David M. Kristensen, Stephen Murray, 2009, Bioinform..

Detection of Biochemical Pathways by Probabilistic Matching of Phyletic Vectors

Michael K. Coleman, David M. Kristensen, Arcady Mushegian, 2009, PloS one.

Systems biology of bacteriophage proteins and new dimensions of the virus world discovered through metagenomics

E. Koonin, A. Mushegian, D. Kristensen, 2011, Genome Biology.

Classification and quantification of bacteriophage taxa in human gut metagenomes

Peer Bork, Shinichi Sunagawa, Eugene V Koonin, 2014, The ISME Journal.

Prokaryotic Virus Orthologous Groups (pVOGs): a resource for comparative genomics and protein family annotation

Eugene V. Koonin, David M. Kristensen, Ana Laura Grazziotin, 2016, Nucleic Acids Res..

No evidence of inhibition of horizontal gene transfer by CRISPR–Cas on evolutionary timescales

Eugene V Koonin, Yuri I Wolf, David M Kristensen, 2015, The ISME Journal.

Microbial genome analysis: the COG approach

Michael Y. Galperin, Eugene V Koonin, Yuri I Wolf, 2019, Briefings Bioinform..

Correction.

K. Kristiansen, S. Brunak, J. Antignac, 2020, Archives of physical medicine and rehabilitation.

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

K. Kristiansen, S. Brunak, B. Le Bizec, 2018, Proceedings of the National Academy of Sciences.

Prediction of enzyme function based on 3D templates of evolutionarily important amino acids

Lydia E. Kavraki, Andreas Martin Lisewski, Olivier Lichtarge, 2008, BMC Bioinformatics.

ATGC database and ATGC-COGs: an updated resource for micro- and macro-evolutionary studies of prokaryotic genomes and protein family annotation

Eugene V. Koonin, Yuri I. Wolf, David M. Kristensen, 2016, Nucleic Acids Res..

Evolutionary Conservation of Bacterial Essential Metabolic Genes across All Bacterial Culture Media

Eytan Ruppin, David M. Kristensen, E. Ruppin, 2015, PloS one.

Contribution of phage-derived genomic islands to the virulence of facultative bacterial pathogens.

Eugene V Koonin, David M Kristensen, Ben Busby, 2013, Environmental microbiology.

Reconstruction of the evolution of microbial defense systems

E. Koonin, Y. Wolf, K. Makarova, 2017, BMC Evolutionary Biology.

Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes

E. Koonin, Y. Wolf, D. Kristensen, 2014, BMC Biology.

Prenatal exposure to perfluoroalkyl substances and anogenital distance at 3 months of age as marker of endocrine disruption.

L. Priskorn, T. K. Jensen, T. H. Lassen, 2016, Reproductive toxicology.

Building Genomic Analysis Pipelines in a Hackathon Setting with Bioinformatician Teams: DNA-seq, Epigenomics, Metagenomics and RNA-seq

Paul W. Bible, Lisa Federer, Allissa Dillman, 2015, bioRxiv.

Many Putative Endocrine Disruptors Inhibit Prostaglandin Synthesis

S. Brunak, H. Leffers, D. Kristensen, 2010, Environmental health perspectives.

The MASH Pipeline for Protein Function Prediction and an Algorithm for the Geometric Refinement of 3D Motifs

Lydia E. Kavraki, Andreas Martin Lisewski, Olivier Lichtarge, 2007, J. Comput. Biol..

Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour.

K. Kristiansen, S. Brunak, B. Jensen, 2017, Reproduction.

Algorithms for Structural Comparison and Statistical Analysis of 3D Protein Motifs

Lydia E. Kavraki, Olivier Lichtarge, Marek Kimmel, 2004, Pacific Symposium on Biocomputing.

ET viewer: an application for predicting and visualizing functional sites in protein structures

Olivier Lichtarge, David M. Kristensen, David Mittelman, 2006, Bioinform..

Geometric Sieving: Automated Distributed Optimization of 3D Motifs for Protein Function Prediction

Lydia E. Kavraki, Andreas Martin Lisewski, Olivier Lichtarge, 2006, RECOMB.

Accurate and scalable identification of functional sites by evolutionary tracing

Olivier Lichtarge, David M. Kristensen, Srinivasan Madabushi, 2004, Journal of Structural and Functional Genomics.

The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

S. Swan, D. Kristensen, A. Mantovani, 2019, Environmental Health.

The PACAP pathway is independent of CGRP in mouse models of migraine: possible new drug target?

D. Kristensen, I. Jansen-Olesen, S. L. Christensen, 2022, Brain : a journal of neurology.

Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.

H. Leffers, D. Kristensen, B. Jégou, 2012, International journal of andrology.

Hypothesis: Metformin is a potential reproductive toxicant

D. Kristensen, N. Skakkebæk, K. Kjær, 2022, Frontiers in Endocrinology.

Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds

S L Christensen, R B Hansen, M A Storm, 2019, European journal of pain.

NCBI’s Virus Discovery Hackathon: Engaging Research Communities to Identify Cloud Infrastructure Requirements

Ryan Shean, Matthew Miller, Carl Leubsdorf, 2019, Genes.

Anogenital Distance: A Marker of Steroidal Endocrine Disruption

S. Swan, D. Kristensen, 2014 .

PACAP signaling is not involved in GTN- and levcromakalim-induced hypersensitivity in mouse models of migraine

D. Kristensen, M. Ashina, A. Hay-Schmidt, 2022, The Journal of Headache and Pain.

NCBI’s Virus Discovery Codeathon: Building “FIVE” —The Federated Index of Viral Experiments API Index

Michael Muchow, Robert A Edwards, Ward Deboutte, 2020, Viruses.

Effects of virion and salt concentrations on the Raman signatures of filamentous phages fd, Pf1, Pf3, and PH75.

D. Kristensen, G. Thomas, S. Overman, 2004, Biochemistry.

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility.

K. Kristiansen, B. Jensen, D. Kristensen, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

K. Kristiansen, S. Brunak, B. Le Bizec, 2018, Proceedings of the National Academy of Sciences.

Comprehensive Evaluation of Blood Plasma and Serum Sample Preparations for HRMS-Based Chemical Exposomics: Overlaps and Specificities.

D. Kristensen, B. Jégou, T. Halldorsson, 2022, Analytical chemistry.