I. Mihalek

发表

An accurate, sensitive, and scalable method to identify functional sites in protein structures.

L. Kavraki, O. Lichtarge, H. Yao, 2003, Journal of molecular biology.

A family of evolution-entropy hybrid methods for ranking protein residues by importance.

O. Lichtarge, I. Mihalek, I. Res, 2004, Journal of molecular biology.

On itinerant water molecules and detectability of protein-protein interfaces through comparative analysis of homologues.

O. Lichtarge, I. Mihalek, I. Res, 2007, Journal of molecular biology.

Determinants, Discriminants, Conserved Residues - A Heuristic Approach to Detection of Functional Divergence in Protein Families

I. Mihalek, Kavitha Bharatham, Z. H. Zhang, 2011, PloS one.

Sequence analysis A structure and evolution-guidedMonte Carlo sequence selection strategy for multiple alignment-based analysis of proteins

O. Lichtarge, I. Mihalek, I. Res, 2006 .

DIVISIONS P 11 HUMAN INFECTIOUS DISEASES P 12 GENOME AND GENE EXPRESSION DATA ANALYSIS DIVISION P 14

V. Kuznetsov, F. Eisenhaber, I. Mihalek, 2012 .

Evolutionary and structural feedback on selection of sequences for comparative analysis of proteins

O. Lichtarge, I. Mihalek, I. Res, 2006, Proteins.

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

M. K. Harper, I. Mihalek, C. Ireland, 2010, Journal of Cell Science.

Cancer-associated mutations in the ribosomal protein L5 gene dysregulate the HDM2/p53-mediated ribosome biogenesis checkpoint

I. Mihalek, J. Bartek, S. Volarevic, 2020, Oncogene.

Molecular map of GNAO1-related disease phenotypes and reactions to therapy

I. Mihalek, A. Poduri, O. Bodamer, 2017 .

Cube - An Online Tool for Comparison and Contrasting of Protein Sequences

I. Mihalek, Z. H. Zhang, A. A. Khoo, 2013, PloS one.

Helix Straightening as an Activation Mechanism in the Gelsolin Superfamily of Actin Regulatory Proteins*

I. Mihalek, R. Robinson, M. Larsson, 2009, The Journal of Biological Chemistry.

Spectrum of neurodevelopmental disease associated with the GNAO1 guanosine triphosphate–binding region

I. Scheffer, I. Mihalek, L. Swanson, 2019, Epilepsia.

The C-Terminal Extension Unique to the Long Isoform of the Shelterin Component TIN2 Enhances Its Interaction with TRF2 in a Phosphorylation- and Dyskeratosis Congenita Cluster-Dependent Fashion

I. Mihalek, A. Bertuch, A. Baldan, 2018, Molecular and Cellular Biology.

TRF2 Interaction with Ku Heterotetramerization Interface Gives Insight into c-NHEJ Prevention at Human Telomeres

I. Mihalek, A. Bertuch, A. Ribes-Zamora, 2013, Cell reports.

Rank information: A structure‐independent measure of evolutionary trace quality that improves identification of protein functional sites

Olivier Lichtarge, O. Lichtarge, H. Yao, 2006, Proteins.

Utility of rapid whole-exome sequencing in the diagnosis of Niemann–Pick disease type C presenting with fetal hydrops and acute liver failure

I. Mihalek, A. O’Donnell-Luria, M. Rohanizadegan, 2017, Cold Spring Harbor molecular case studies.

ExoLocator—an online view into genetic makeup of vertebrate proteins

Matija Korpar, Mile Sikic, Ivana Mihalek, 2013, Nucleic Acids Res..

Cube-DB: detection of functional divergence in human protein families

Zong Hong Zhang, Ivana Mihalek, Kavitha Bharatham, 2011, Nucleic Acids Res..

Combining inference from evolution and geometric probability in protein structure evaluation.

O. Lichtarge, H. Yao, I. Mihalek, 2003, Journal of molecular biology.

A novel FAM20C mutation causes a rare form of neonatal lethal Raine syndrome

I. Mihalek, O. Bodamer, M. Bauer, 2019, American journal of medical genetics. Part A.

BIOINFORMATICS ORIGINAL PAPER Systems biology

Olivier Lichtarge, I. Mihalek, I. Res, 2004 .

Manifestation of hawkinsinuria in a patient compound heterozygous for hawkinsinuria and tyrosinemia III.

I. Mihalek, O. Bodamer, J. Vodopiutz, 2007, Molecular genetics and metabolism.

Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions

Olivier Lichtarge, Albert Ribes-Zamora, O. Lichtarge, 2007, Nature Structural &Molecular Biology.

Defining the Phenotype in Congenital Disorder of Glycosylation Due to ALG1 Mutations

I. Mihalek, R. Wevers, Z. H. Zhang, 2012, Pediatrics.

Background frequencies for residue variability estimates: BLOSUM revisited

Olivier Lichtarge, I. Mihalek, I. Res, 2007, BMC Bioinformatics.

Accurate and scalable identification of functional sites by evolutionary tracing

Olivier Lichtarge, David M. Kristensen, Srinivasan Madabushi, 2004, Journal of Structural and Functional Genomics.

Active site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling.

Srinath Krishnamurthy, Ganesh S Anand, Kavitha Bharatham, 2014, Biophysical journal.

Evolutionary trace report_maker: a new type of service for comparative analysis of proteins

Olivier Lichtarge, I. Mihalek, I. Res, 2006, Bioinform..

Mutations in RIT1 cause Noonan syndrome – additional functional evidence and expanding the clinical phenotype

I. Mihalek, K. Gripp, G. Shi, 2016, Clinical genetics.

deconSTRUCT: general purpose protein database search on the substructure level

Zong Hong Zhang, Ivana Mihalek, Westley A. Sherman, 2010, Nucleic Acids Res..

A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure

M. Tekin, I. Mihalek, E. Gussoni, 2017, PloS one.

Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity

Hwee Kuan Lee, Zong Hong Zhang, Ivana Mihalek, 2010, BMC Bioinformatics.

Defining the Phenotype in Congenital Disorder of Glycosylation Due to ALG1 Mutations

I. Mihalek, R. Wevers, Z. H. Zhang, 2012, Pediatrics.