G. Amidon

发表

Establishing the pharmaceutical quality of Chinese herbal medicine: a provisional BCS classification.

S. Fong, M. Liu, H. Wei, 2013, Molecular pharmaceutics.

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification.

G. Amidon, N. A. Kasim, M. Whitehouse, 2004, Molecular pharmaceutics.

Absorption potential: estimating the fraction absorbed for orally administered compounds.

G. Amidon, J. Dressman, D. Fleisher, 1985, Journal of pharmaceutical sciences.

Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants

Jason R. Baker, L. Marciani, R. Spiller, 2020, PloS one.

Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential

G. Amidon, G. Saito, K-D Lee, 2003, Gene Therapy.

Design of compounds that increase the absorption of polar molecules.

S. Choe, G. Amidon, P. Venkatesan, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Drug Marker Absorption in Relation to Pellet Size, Gastric Motility and Viscous Meals in Humans

Jeremy J. Frens, G. Amidon, G. Amidon, 1998, Pharmaceutical Research.

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

J. Crison, G. Amidon, H. Lennernäs, 1995, Pharmaceutical Research.

The Biopharmaceutics Classification System: subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC.

G. Amidon, D. Mudie, G. Amidon, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state.

Martin C Garnett, Luca Marciani, Gordon L Amidon, 2014, Molecular pharmaceutics.

Hydrophobicity of polycyclic aromatic compounds. Thermodynamic partitioning analysis

G. Amidon, S. Anik, 1980 .

Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions

Vinod P. Shah, Lawrence X. Yu, Ajaz S. Hussain, 2002, Pharmaceutical Research.

In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome.

Lawrence X. Yu, Lawrence X Yu, Gordon L Amidon, 2004, Current opinion in drug discovery & development.

A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan.

Lawrence X. Yu, Lawrence X Yu, Marival Bermejo, 2006, Molecular pharmaceutics.

Evidence for Overlapping Substrate Specificity Between Large Neutral Amino Acid (LNAA) and Dipeptide (hPEPTl) Transporters for PD 158473, an NMDA Antagonist

G. Amidon, W. Sadee, R. M. Williamson, 2004, Pharmaceutical Research.

Mechanisms of Drug Interactions

G. Amidon, P. Welling, J. McElnay, 1996, Handbook of Experimental Pharmacology.

A pH- and ionic strength-responsive polypeptide hydrogel: synthesis, characterization, and preliminary protein release studies.

G L Amidon, G. Amidon, V. Yang, 1999, Journal of biomedical materials research.

Synthesis and characterization of valyloxy methoxy luciferin for the detection of valacyclovirase and peptide transporter.

G. Amidon, Kyung-Dall Lee, Z. Walls, 2014, Bioorganic & medicinal chemistry letters.

A compartmental absorption and transit model for estimating oral drug absorption.

G L Amidon, G. Amidon, L. Yu, 1999, International journal of pharmaceutics.

Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time

Bo Wen, Yasuhiro Tsume, Gordon L. Amidon, 2017, The AAPS Journal.

Drug targeting strategies for the treatment of inflammatory bowel disease: a mechanistic update

G. Amidon, A. Dahan, E. Zimmermann, 2010, Expert review of clinical immunology.

Compartmental transit and dispersion model analysis of small intestinal transit flow in humans

Lawrence X. Yu, Gordon L. Amidon, J. Crison, 1996 .

Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption.

G L Amidon, Lawrence X. Yu, J. Crison, 1996, Advanced drug delivery reviews.

Human effective permeability data forrurosemide, hydrochlorthiazide, ketoprofen and naproxen to be used in the proposed biopharmaceutical drug classification system for IR-products

G. Amidon, L. Lesko, L. Knutson, 1996 .

Characterization of small intestinal transit time distribution in humans

Lawrence X. Yu, Gordon L. Amidon, G. Amidon, 1998 .

Solubility of nonelectrolytes in polar solvents. VI. Refinements in molecular surface area computations

Samuel H. Yalkowsky, Gordon L. Amidon, S. Yalkowsky, 1976 .

Ion pairing with bile salts modulates intestinal permeability and contributes to food-drug interaction of BCS class III compound trospium chloride.

G. Amidon, S. Reuss, P. Langguth, 2013, Molecular pharmaceutics.

Viscoelasticity of Anionic Polymers and Their Mucociliary Transport on the Frog Palate

N. Weiner, G. Amidon, Shun Y. Lin, 1993, Pharmaceutical Research.

Characterization of the oral absorption of beta-lactam antibiotics. II. Competitive absorption and peptide carrier specificity.

G. Amidon, P. Sinko, 1989, Journal of pharmaceutical sciences.

Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.

G. Amidon, A. Dahan, 2009, Molecular pharmaceutics.

Intestinal permeability study of minoxidil: assessment of minoxidil as a high permeability reference drug for biopharmaceutics classification.

G. Amidon, A. Dahan, M. Ozawa, 2015, Molecular pharmaceutics.

In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.

G. Amidon, G. Amidon, S. Taghavi, 2014, Journal of pharmaceutical sciences.

Excess free energy approach to the estimation of solubility in mixed solvent systems I: Theory.

G. Amidon, N. A. Williams, 1984, Journal of pharmaceutical sciences.

Excess free energy approach to the estimation of solubility in mixed solvent systems III: Ethanol-propylene glycol-water mixtures.

G. Amidon, N. A. Williams, 1984, Journal of pharmaceutical sciences.

Controlled release of ethanehydroxy diphosphonate from polyurethane reservoirs to inhibit calcification of bovine pericardium used in bioprosthetic heart valves

R. Levy, G. Amidon, F. Schoen, 1990 .

Controlled release of 1-hydroxyethylidene diphosphonate: in vitro assessment and effects on bioprosthetic calcification in sheep tricuspid valve replacements

R. Levy, G. Amidon, S. Bolling, 1989 .

Plasticizer-induced changes in the mechanical rate of response of film coatings: an approach to quantitating plasticizer effectiveness

G. Amidon, C. M. Sinko, 1989 .

Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)

G. Amidon, M. Bermejo, B. Hens, 2020, Pharmaceutics.

Physiological parameters for oral delivery and in vitro testing.

G. Amidon, D. Mudie, G. Amidon, 2010, Molecular pharmaceutics.

In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib.

G. Amidon, G. Amidon, K. Matsui, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Drug Interactions in the Gastrointestinal Tract and Their Impact on Drug Absorption and Systemic Availability: A Mechanistic Review

J. Crison, G. Amidon, B. Schug, 1996 .

Potential Development of Tumor-Targeted Oral Anti-Cancer Prodrugs: Amino Acid and Dipeptide Monoester Prodrugs of Gemcitabine

G. Amidon, Y. Tsume, David E. Smith, 2017, Molecules.

Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

B. Vig, Ho-Chul Shin, G. Amidon, 2003, Biochemical and biophysical research communications.

Summary of the National Institute of Child Health and Human Development-best pharmaceuticals for Children Act Pediatric Formulation Initiatives Workshop-Pediatric Biopharmaceutics Classification System Working Group.

G. Amidon, V. Lukacova, A. Vinks, 2012, Clinical therapeutics.

Magnetic Resonance Imaging Quantification of Fasted State Colonic Liquid Pockets in Healthy Humans.

L. Marciani, R. Spiller, G. Amidon, 2017, Molecular pharmaceutics.

Design of prodrugs for improved gastrointestinal absorption by intestinal enzyme targeting.

G. Amidon, D. Fleisher, B. H. Stewart, 1985, Methods in enzymology.

The in vivo predictive dissolution for immediate release dosage of donepezil and danazol, BCS class IIc drugs, with the GIS and the USP II with biphasic dissolution apparatus

G. Amidon, G. Amidon, H. Ruan, 2020 .

Summary of the In Vivo Predictive Dissolution (iPD) - Oral Drug Delivery (ODD) Conference 2018

R. Ziff, L. Marciani, R. Löbenberg, 2018 .

Pharmacokinetics of probenecid following oral doses to human volunteers.

G. Amidon, P. Welling, A. Selen, 1982, Journal of pharmaceutical sciences.

Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications.

Jason R. Baker, G. Amidon, M. Bermejo, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Modified polypeptides containing γ-benzyl glutamic acid as drug delivery platforms

G. Amidon, V. Yang, P. Markland, 1999 .

Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.

G. Amidon, D. Fleisher, T. Heimbach, 2002, The Journal of pharmacology and experimental therapeutics.

Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution.

Yasuhiro Tsume, Gordon L Amidon, G. Amidon, 2014, Journal of pharmaceutical sciences.

An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products

G. Amidon, M. Bermejo, B. Hens, 2021, Pharmaceutics.

The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene.

G. Amidon, G. Amidon, Y. Tsume, 2018, Journal of pharmaceutical sciences.

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

G. Amidon, J. Brasseur, M. Bermejo, 2018, The AAPS Journal.

Scale-up of oral extended-release dosage forms

Mario A. González, W. H. Barr, G. Amidon, 1995 .

Scale-up of immediate release oral solid dosage forms. AAPS/FDA Workshop Committee Report.

G. Amidon, A. Malick, J. Skelly, 1993, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

Workshop report : scale-up of immediate release oral solid dosage forms

Mario A. González, G. Amidon, V. Shah, 1992 .

Pharmacokinetics of Alcohol Following Single Low Doses to Fasted and Nonfasted Subjects

G. Amidon, P. Welling, L. L. Lyons, 1977, Journal of clinical pharmacology.

A peptide prodrug approach for improving bisphosphonate oral absorption.

I. Alferiev, H. Cohen, G. Golomb, 2000, Journal of medicinal chemistry.

The Dipeptide Monoester Prodrugs of Floxuridine and Gemcitabine—Feasibility of Orally Administrable Nucleoside Analogs

G. Amidon, Y. Tsume, B. Bermejo, 2014, Pharmaceuticals.

The Site-Specific Transport and Metabolism of Tacrolimus in Rat Small Intestine

G. Amidon, S. Yamashita, R. Ibuki, 2003, Journal of Pharmacology and Experimental Therapeutics.

Comparative gene expression of intestinal metabolizing enzymes

A. A. Abd El-Aty, Ho-Chul Shin, G. Amidon, 2009, Biopharmaceutics & drug disposition.

Lessons learned from marketed and investigational prodrugs.

B. Testa, G. Amidon, P. Ettmayer, 2004, Journal of medicinal chemistry.

Drug transport and targeting. Intestinal transport.

G. Amidon, D. Oh, H. Han, 1999, Pharmaceutical biotechnology.

Comparative gene expression profiles of intestinal transporters in mice, rats and humans.

A. A. Abd El-Aty, Ho-Chul Shin, G. Amidon, 2007, Pharmacological research.

Gene Expression in the Human Intestine and Correlation with Oral Valacyclovir Pharmacokinetic Parameters

G. Amidon, C. Ramachandran, D. Foster, 2003, Journal of Pharmacology and Experimental Therapeutics.

Modeling drug release from dynamically swelling poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels

G. Amidon, D. Fleisher, J. Kou, 1990 .

Comparison of gastrointestinal pH in dogs and humans: implications on the use of the beagle dog as a model for oral absorption in humans.

G. Amidon, J. Dressman, D. Fleisher, 1986, Journal of pharmaceutical sciences.

Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein

G. Amidon, D. Fleisher, Duxin Sun, 2001, AAPS PharmSci.

The Molecular Weight Dependence of Nasal Absorption: The Effect of Absorption Enhancers

G. Flynn, G. Amidon, M. Donovan, 1990, Pharmaceutical Research.

Specificity of a prodrug-activating enzyme hVACVase: the leaving group effect.

G. Amidon, Kyung-Dall Lee, A. Dahan, 2010, Molecular pharmaceutics.

Pharmacokinetics and Pharmacodynamics of Nifedipine in Children with Bronchopulmonary Dysplasia and Pulmonary Hypertension

G. Amidon, R. Beekman, Cary E. Johnson, 1991, Pediatric Research.

Mechanistic enhancement of the intestinal absorption of drugs containing the polar guanidino functionality

G. Amidon, A. Dahan, Liat Rozen, 2011, Expert opinion on drug metabolism & toxicology.

Effects of Gravity on Gastric Emptying, Intestinal Transit, and Drug Absorption

G. Amidon, N. Najib, Gary A. DeBrincat, 1991, Journal of clinical pharmacology.

Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme.

G. Amidon, C. McKenna, C. Nelson, 2010, Antiviral research.

Absorption of Polyethylene Glycols 600 Through 2000: The Molecular Weight Dependence of Gastrointestinal and Nasal Absorption

G. Flynn, G. Amidon, M. Donovan, 1990, Pharmaceutical Research.

Human Jejunal Permeability of Cyclosporin A: Influence of Surfactants on P-Glycoprotein Efflux in Caco-2 Cells

G. Amidon, L. Welage, J. Barnett, 2003, Pharmaceutical Research.

Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model

R. Löbenberg, G. Amidon, M. Bermejo, 2018, The AAPS Journal.

MRP2 mediated drug-drug interaction: indomethacin increases sulfasalazine absorption in the small intestine, potentially decreasing its colonic targeting.

G. Amidon, A. Dahan, 2010, International journal of pharmaceutics.

A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein.

B. Vig, Ho-Chul Shin, G. Amidon, 2004, Molecular pharmaceutics.

Oral absorption of phytosterols and emulsified phytosterols by Sprague-Dawley rats.

G. Amidon, D. Kritchevsky, Y. Tsume, 2004, The Journal of nutritional biochemistry.

Mechanistic analysis and experimental verification of bicarbonate‐controlled enteric coat dissolution: Potential in vivo implications

G. Amidon, M. Bermejo, G. Amidon, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Radiotelemetric method for evaluating enteric coatings in vivo.

G. Amidon, J. Dressman, 1984, Journal of pharmaceutical sciences.

Comparison of gastrointestinal pH in cystic fibrosis and healthy subjects

G. Amidon, J. Dressman, R. Berardi, 1987, Digestive Diseases and Sciences.

Intestinal absorption of amino acid derivatives: structural requirements for membrane hydrolysis.

G. Amidon, M. Lee, H. Lee, 1983, Journal of pharmaceutical sciences.

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

Kerby Shedden, Marival Bermejo, Bart Hens, 2020, Pharmaceutics.

Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling

G. Amidon, M. Bermejo, B. Hens, 2022, The AAPS Journal.

Mass Transport Analysis of Bicarbonate Buffer: Effect of the CO2-H2CO3 Hydration-Dehydration Kinetics in the Fluid Boundary Layer and the Apparent Effective p Ka Controlling Dissolution of Acids and Bases.

R. Ziff, G. Amidon, G. Amidon, 2019, Molecular pharmaceutics.

Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate-CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance.

G. Amidon, M. Bermejo, B. Hens, 2018, Molecular pharmaceutics.

In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.

Jason R. Baker, G. Amidon, R. Lionberger, 2017, Molecular pharmaceutics.

Toward Biopredictive Dissolution for Enteric Coated Dosage Forms.

G. Amidon, P. Langguth, J. Al-Gousous, 2016, Molecular pharmaceutics.

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.

Kerby Shedden, Jianghong Fan, Marival Bermejo, 2017, Molecular pharmaceutics.

Biphasic Dissolution as an Exploratory Method during Early Drug Product Development

N. Davies, R. Löbenberg, G. Amidon, 2020, Pharmaceutics.

Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution

Jason R. Baker, G. Amidon, Trachette L. Jackson, 2019, The AAPS Journal.

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.

Jason R. Baker, R. Löbenberg, G. Amidon, 2018, Molecular pharmaceutics.

Transporter mRNA expression in a conditionally immortalized rat small intestine epithelial cell line (TR-SIE).

G. Amidon, M. Obinata, T. Terasaki, 2004, Drug metabolism and pharmacokinetics.

Gastrointestinal Uptake of Biodegradable Microparticles: Effect of Particle Size

Gordon L. Amidon, Robert J. Levy, R. Levy, 1996, Pharmaceutical Research.

Mathematical model and dimensional analysis of glycocholate binding to cholestyramine resin: implications for in vivo resin performance.

J. Polli, G. Amidon, 1995, Journal of pharmaceutical sciences.

The effect of enzyme inhibitor and absorption site following [D‐ala2, D‐leu5]enkephalin oral administration in rats

G. Amidon, Hye J Lee, 2002, Biopharmaceutics & drug disposition.

Equilibrium and Kinetic Factors Influencing Bile Sequestrant Efficacy

G. Amidon, P. Luner, 1992, Pharmaceutical Research.

Description and simulation of a multiple mixing tank model to predict the effect of bile sequestrants on bile salt excretion.

G. Amidon, P. Luner, 1993, Journal of pharmaceutical sciences.

Application of the surface area approach to the correlation and estimation of aqueous solubility and vapor pressure. Alkyl aromatic hydrocarbons

G. Amidon, S. Anik, 1981 .

Effect of size and density on canine gastric emptying of nondigestible solids.

G. Amidon, J. Meyer, J. Dressman, 1985, Gastroenterology.

Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Novel Valacyclovir-Activating Enzyme.

G. Amidon, Hao-Jie Zhu, Jian Shi, 2020, Molecular pharmaceutics.

Peptide-based Drug Design, Controlling Transport and Metabolism

G. Amidon, Michael D. Taylor, 1995 .

Moisture sorption kinetics for water-soluble substances. I: Theoretical considerations of heat transport control.

G. Amidon, G. Zografi, L. Van Campen, 1983, Journal of pharmaceutical sciences.

Theoretical calculation of heats of complexation in carbon tetrachloride.

G. Amidon, 1974, Journal of pharmaceutical sciences.

Enhancing the intestinal absorption of molecules containing the polar guanidino functionality: a double-targeted prodrug approach.

G. Amidon, A. Dahan, Jing Sun, 2010, Journal of medicinal chemistry.

Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

B. Vig, Ho-Chul Shin, G. Amidon, 2006, Biological & pharmaceutical bulletin.

Floxuridine Amino Acid Ester Prodrugs: Enhancing Caco-2 Permeability and Resistance to Glycosidic Bond Metabolism

G. Amidon, Xueqin Song, P. Lorenzi, 2005, Pharmaceutical Research.

Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.

B. Vig, G. Amidon, Xueqin Song, 2005, Journal of medicinal chemistry.

Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme.

G. Amidon, H. Mosberg, P. Subramanian, 1992, Journal of pharmaceutical sciences.

Proline Prodrug of Melphalan Targeted to Prolidase, a Prodrug Activating Enzyme Overexpressed in Melanoma

B. Vig, G. Amidon, Xueqin Song, 2007, Pharmaceutical Research.

Prediction of Physical Aging in Controlled-Release Coatings: The Application of the Relaxation Coupling Model to Glassy Cellulose Acetate

G. Amidon, A. Yee, C. M. Sinko, 1991, Pharmaceutical Research.

Interferon-gamma increases expression of the di/tri-peptide transporter, h-PEPT1, and dipeptide transport in cultured human intestinal monolayers.

G. Amidon, D. Foster, L. Welage, 2009, Pharmacological research.

"5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter,".

G. Amidon, C. R. Walgreen, 1999, Pharmaceutical research.

Report from the “3rd International Symposium on BA/BE of Oral Drug Products: Biopharmaceutics meets Galenics”

G. Amidon, M. Bermejo, K. Kawakami, 2020 .

Pharmacokinetics of cefazolin in normal and uremic subjects

G. Amidon, P. Welling, W. Craig, 1974, Clinical pharmacology and therapeutics.

Intestinal dipeptide absorption is preserved during thermal injury and cytokine treatment.

G. Amidon, J. Gonzales, D. Foster, 2009, JPEN. Journal of parenteral and enteral nutrition.

Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction

G. Amidon, H. Merkle, Cheng-Pang Hsu, 1998, Pharmaceutical Research.

Enhanced Absorption and Growth Inhibition with Amino Acid Monoester Prodrugs of Floxuridine by Targeting hPEPT1 Transporters

B. Vig, G. Amidon, C. Ramachandran, 2008, Molecules.

Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability.

Lawrence X. Yu, Ho-Chul Shin, G. Amidon, 2005, Molecular pharmaceutics.

On the use of a dynamic approach to the estimation of dissociation constants for reversible competitive antagonists.

G. Amidon, C. Buckner, 1981, The Journal of pharmacology and experimental therapeutics.

The development of orally administrable gemcitabine prodrugs with D-enantiomer amino acids: enhanced membrane permeability and enzymatic stability.

G. Amidon, Xueqin Song, Y. Tsume, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Enhancing the intestinal membrane permeability of zanamivir: a carrier mediated prodrug approach.

G. Amidon, Kyung-Dall Lee, A. Dahan, 2011, Molecular pharmaceutics.

Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers.

G. Amidon, Kyung-Dall Lee, Sheeba Varghese Gupta, 2009, Molecular pharmaceutics.

Enhanced Cancer Cell Growth Inhibition by Dipeptide Prodrugs of Floxuridine: Increased Transporter Affinity and Metabolic Stability

G. Amidon, Y. Tsume, J. Hilfinger, 2008, Molecular pharmaceutics.

Effect of experimental acute renal and hepatic failure on absorption of tacrolimus in rat small intestine.

G. Amidon, S. Yamashita, A. Ohike, 2004, Drug metabolism and pharmacokinetics.

Transdermal Delivery of Bioactive Peptides: The Effect of n-Decylmethyl Sulfoxide, pH, and Inhibitors on Enkephalin Metabolism and Transport

G. Flynn, G. Amidon, Hoo-Kyun Choi, 2004, Pharmaceutical Research.

In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil.

G. Amidon, Duxin Sun, M. R. Feng, 2022, Molecular pharmaceutics.

Effects of viscosity and fluid outflow on postcibal gastric emptying of solids.

J. Elashoff, G. Amidon, J. Meyer, 1986, The American journal of physiology.

Determinants of the Modulated Release of Antiarrhythmic Drugs by Iontophoresis through Polymer Membranes

R. Levy, G. Amidon, S. Schwendeman, 1993 .

Passive and Carrier-Mediated Intestinal Absorption Components of Two Angiotensin Converting Enzyme (ACE) Inhibitor Prodrugs in Rats: Enalapril and Fosinopril

G. Amidon, D. Friedman, 1989, Pharmaceutical Research.

Investigation into the intestinal metabolism of [D-Ala1] peptide T amide: implication for oral drug delivery.

G. Amidon, S. Su, 1995, Biochimica et biophysica acta.

Stability of valacyclovir: implications for its oral bioavailability.

G. Amidon, G. Granero, 2006, International journal of pharmaceutics.

The intestinal peptide carrier: A potential transport system for small peptide derived drugs

G. Amidon, T. Kissel, E. Walter, 1996 .

Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards.

R. Löbenberg, G. Amidon, 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.

G L Amidon, P Langguth, G. Amidon, 2000, Journal of pharmaceutical sciences.

Provisional biopharmaceutical classification of some common herbs used in Western medicine.

R. Löbenberg, I. Kanfer, G. Amidon, 2012, Molecular pharmaceutics.

Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model

Ho-Chul Shin, Lawrence X. Yu, Duxin Sun, 2006, Pharmaceutical Research.

Absorption of peptide and peptidomimetic drugs.

G L Amidon, G. Amidon, H J Lee, 1994, Annual review of pharmacology and toxicology.

Physicochemical property modification strategies based on enzyme substrate specificities I: rationale, synthesis, and pharmaceutical properties of aspirin derivatives.

G. Amidon, P. K. Banerjee, 1981, Journal of pharmaceutical sciences.

Bio-predictive tablet disintegration: effect of water diffusivity, fluid flow, food composition and test conditions.

G. Amidon, M. Wagner, P. Langguth, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Feasibility studies of utilizing disk intrinsic dissolution rate to classify drugs.

Lawrence X. Yu, Lawrence X Yu, Gordon L Amidon, 2004, International journal of pharmaceutics.

Characterization of the intestinal transport parameters for small peptide drugs

G. Amidon, D. Friedman, 1990 .

In silico prediction of drug dissolution and absorption with variation in intestinal pH for BCS class II weak acid drugs: ibuprofen and ketoprofen

G. Amidon, P. Langguth, A. García‐Arieta, 2012, Biopharmaceutics & drug disposition.

Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists

Valentino J. Stella, Gordon L. Amidon, K. A. Connors, 1979 .

Membrane Transporters as Drug Targets

G. Amidon, W. Sadee, 2002, Pharmaceutical Biotechnology.

Reaction of Aspirin with Amines. Potential Mechanism for Aspirin Allergy

G. Amidon, M. Schwartz, 1966 .

The BCS, BDDCS, and Regulatory Guidances

Lawrence X. Yu, G. Amidon, L. Benet, 2011, Pharmaceutical Research.

Setting bioequivalence requirements for drug development based on preclinical data: optimizing oral drug delivery systems.

G. Amidon, E. Lipka, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Thermodynamic studies on the gel-sol transition of some pluronic polyols

Gordon L. Amidon, G. Amidon, J. Haslam, 1984 .

Solubility of nonelectrolytes in polar solvents III: Alkyl p-aminobenzoates in polar and mixed solvents.

S. Yalkowsky, G. Flynn, G. Amidon, 1975, Journal of pharmaceutical sciences.

Intestinal Transport of Gentamicin with a Novel, Glycosteroid Drug Transport Agent

S. Choe, G. Amidon, H. Axelrod, 1998, Pharmaceutical Research.

Solubility of nonelectrolytes in polar solvents IV: nonpolar drugs in mixed solvents.

G L Amidon, S. Yalkowsky, G. Amidon, 1976, Journal of pharmaceutical sciences.

Solubility of nonelectrolytes in polar solvents.

G L Amidon, S. Yalkowsky, G. Flynn, 1972, Journal of pharmaceutical sciences.

The biowaiver extension for BCS class III drugs: the effect of dissolution rate on the bioequivalence of BCS class III immediate-release drugs predicted by computer simulation.

Yasuhiro Tsume, Gordon L. Amidon, G. Amidon, 2010, Molecular pharmaceutics.

Solubility of nonelectrolytes in polar solvents II: solubility of aliphatic alcohols in water.

G L Amidon, S. Yalkowsky, G. Amidon, 1974, Journal of pharmaceutical sciences.

Cytomegalovirus Protease Targeted Prodrug Development

G. Amidon, Kyung-Dall Lee, A. Dahan, 2013, Molecular pharmaceutics.

Structure and reactivity of theobrominate and theophyllinate complexes with methyl trans-cinnamate.

G. Amidon, 1974, Journal of pharmaceutical sciences.

Comparison of theoretical, absolute interaction energies with heats of complexation in carbon tetrachloride.

G. Amidon, 1974, Journal of pharmaceutical sciences.

The low/high BCS permeability class boundary: physicochemical comparison of metoprolol and labetalol.

G. Amidon, Omri Wolk, A. Dahan, 2014, Molecular pharmaceutics.

The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation.

G. Amidon, G. Amidon, A. Dahan, 2011, Molecular pharmaceutics.

The solubility-permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone.

Gordon L Amidon, Arik Dahan, G. Amidon, 2010, Journal of pharmaceutical sciences.

Prediction of Solubility and Permeability Class Membership: Provisional BCS Classification of the World’s Top Oral Drugs

Gordon L. Amidon, Arik Dahan, G. Amidon, 2009, The AAPS Journal.

Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat.

Brady T. West, G. Amidon, B. West, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media.

G. Amidon, G. Amidon, K. Matsui, 2016, Journal of pharmaceutical sciences.

Solubility of nonelectrolytes in polar solvents. V. Estimation of the solubility of aliphatic monofunctional compounds in water using a molecular surface area approach

Samuel H. Yalkowsky, Gordon L. Amidon, S. Yalkowsky, 1975 .

Structural Specificity of Mucosal-Cell Transport and Metabolism of Peptide Drugs: Implication for Oral Peptide Drug Delivery

G. Amidon, J. Bai, 1992, Pharmaceutical Research.

Moisture sorption kinetics for water-soluble substances. II: Experimental verification of heat transport control.

G. Amidon, G. Zografi, L. Van Campen, 1983, Journal of pharmaceutical sciences.

Targeted prodrug design to optimize drug delivery

Gordon L. Amidon, Hyo-Kyung Han, G. Amidon, 2000, AAPS PharmSci.

Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms

Christos Reppas, Vinod P. Shah, Gordon L. Amidon, 2004, Pharmaceutical Research.

Oral product input to the GI tract: GIS an oral product performance technology

Yasuhiro Tsume, Gordon L. Amidon, G. Amidon, 2017, Frontiers of Chemical Science and Engineering.

Solubilization and dissolution of insoluble weak acid, ketoprofen: effects of pH combined with surfactant.

Gordon L Amidon, G. Amidon, N. A. Kasim, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS)

Kazuki Matsui, Yasuhiro Tsume, Gordon L Amidon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Application of a radiotelemetric system to evaluate the performance of enteric coated and plain aspirin tablets.

G. Amidon, D. Fleisher, R. Oberle, 1986, Journal of pharmaceutical sciences.

Dissolution of ionizable water-insoluble drugs: the combined effect of pH and surfactant.

G L Amidon, J. Crison, G. Amidon, 2000, Journal of pharmaceutical sciences.

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro‐in silico‐in vivo approach

Marival Bermejo, Bart Hens, Gregory E. Amidon, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach.

D. A. Johnson, G. Amidon, P. Sinko, 1988, Journal of theoretical biology.

Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs.

G. Amidon, A. Dahan, Jonathan M. Miller, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis.

R. Ziff, G. Amidon, G. Amidon, 2021, Molecular pharmaceutics.

The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests.

G. Amidon, Y. Tsume, J. Hilfinger, 2006, Molecular pharmaceutics.

Surfactant-mediated dissolution: contributions of solubility enhancement and relatively low micelle diffusivity.

Anand Balakrishnan, James E Polli, Gordon L Amidon, 2004, Journal of pharmaceutical sciences.

Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Dissolution Behavior of Glibenclamide

Raimar Löbenberg, Vinod P. Shah, Johannes Krämer, 2000, Pharmaceutical Research.

The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil

G. Amidon, A. Dahan, S. Cvijić, 2022, Pharmaceutics.

Biowaiver monographs for immediate release solid oral dosage forms: isoniazid.

D. Barends, G. Amidon, H. Junginger, 2007, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms: diclofenac sodium and diclofenac potassium.

D. Barends, J. Polli, G. Amidon, 2009, Journal of pharmaceutical sciences.

Simulated, biorelevant, clinically relevant or physiologically relevant dissolution media: The hidden role of bicarbonate buffer.

N. Davies, R. Löbenberg, G. Amidon, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Toward an in vivo dissolution methodology: a comparison of phosphate and bicarbonate buffers.

Gordon L Amidon, G. Amidon, Jennifer J Sheng, 2009, Molecular pharmaceutics.

Pharmacokinetics of trimethoprim and sulfamethoxazole in normal subjects and in patients with renal failure.

G. Amidon, P. Welling, W. Craig, 1973, The Journal of infectious diseases.

Intranasal absorption of flurazepam, midazolam, and triazolam in dogs.

G. Amidon, A. Goldberg, C. Lui, 1991, Journal of pharmaceutical sciences.

The challenge of proteolytic enzymes in intestinal peptide delivery

G. Amidon, S. Wolffram, H. Merkle, 1997 .

Biowaiver monographs for immediate release solid oral dosage forms: aciclovir.

D. Barends, G. Amidon, M. Bermejo, 2008, Journal of pharmaceutical sciences.

Dissolution media for in vitro testing of water-insoluble drugs: effect of surfactant purity and electrolyte on in vitro dissolution of carbamazepine in aqueous solutions of sodium lauryl sulfate.

J. Crison, G. Amidon, N. Weiner, 1997, Journal of pharmaceutical sciences.

Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.

Jayanth Panyam, Robert J Levy, Gordon L Amidon, 2003, Journal of controlled release : official journal of the Controlled Release Society.

pH-Dependent Swelling and Solute Diffusion Characteristics of Poly(Hydroxyethyl Methacrylate–CO–Methacrylie Acid) Hydrogels

G. Amidon, Ping I. Lee, J. H. Kou, 1988, Pharmaceutical Research.

Comparison of the permeability of metoprolol and labetalol in rat, mouse, and Caco-2 cells: use as a reference standard for BCS classification.

G. Amidon, Y. Tsume, T. Incecayir, 2013, Molecular pharmaceutics.

Drug dissolution into micellar solutions: development of a convective diffusion model and comparison to the film equilibrium model with application to surfactant-facilitated dissolution of carbamazepine.

J. Crison, G. Amidon, V. Shah, 1996, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: verapamil hydrochloride, propranolol hydrochloride, and atenolol.

G L Amidon, D M Barends, M Olling, 2004, Journal of pharmaceutical sciences.

Fetal and maternal tissue distribution of the new fluoroquinolone DW-116 in pregnant rats.

Ho-Chul Shin, G. Amidon, Mi-Kyung Lee, 2003, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Thermodynamic aspects of the disappearance of antiplasticization in slightly plasticized polymer films at high temperature.

G. Amidon, R. E. Robertson, J. H. Guo, 1992, Journal of pharmaceutical sciences.

Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes.

Brent R. Martin, H. Carlson, G. Amidon, 2015, Molecular pharmaceutics.

Biowaiver monographs for immediate release solid oral dosage forms: acetaminophen (paracetamol).

D. Barends, G. Amidon, H. Junginger, 2006, Journal of pharmaceutical sciences.

A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

Gordon L Amidon, Marilyn N Martinez, G. Amidon, 2002, Journal of clinical pharmacology.

Possible degradative process of cholecystokinin analogs in rabbit jejunum brush-border membrane vesicles.

G. Amidon, S. Su, Hye J Lee, 2002, Life sciences.

Intestinal metabolism and absorption of cholecystokinin analogs in rats.

G. Amidon, S. Su, Hye J Lee, 2002, Biochemical and biophysical research communications.

Gastrointestinal Dissolution and Absorption of Drugs

G. Amidon, C. Ramachandran, G. Granero, 2004 .

Carrier mediated transport of amino acids, small peptides, and their drug analogs

G. Amidon, P. Sinko, Ming Hu, 1987 .

CARRIER MEDIATED TRANSPORT OF AMINO ACIDS, THEIR DRUG ANALOGS*

G. Amidon, P. Sinko, Ming Hu, 1987 .

High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations.

Lawrence X. Yu, G. Amidon, H. Lennernäs, 2010, Molecular pharmaceutics.

Multiple Efflux Pumps Are Involved in the Transepithelial Transport of Colchicine: Combined Effect of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 Leads to Decreased Intestinal Absorption Throughout the Entire Small Intestine

G. Amidon, A. Dahan, Hairat Sabit, 2009, Drug Metabolism and Disposition.

Grapefruit Juice and its Constituents Augment Colchicine Intestinal Absorption: Potential Hazardous Interaction and the Role of P-Glycoprotein

G. Amidon, A. Dahan, 2009, Pharmaceutical Research.

Noncompetitive inhibition of cephradine uptake by enalapril in rabbit intestinal brush-border membrane vesicles: an enalapril specific inhibitory binding site on the peptide carrier.

G. Amidon, D. Fleisher, H. Yuasa, 1994, The Journal of pharmacology and experimental therapeutics.

Determination of intrinsic membrane transport parameters from perfused intestine experiments: a boundary layer approach to estimating the aqueous and unbiased membrane permeabilities.

D. A. Johnson, G. Amidon, Gordon L. Amidon, 1988, Journal of theoretical biology.

Selection of suitable prodrug candidates for in vivo studies via in vitro studies; the correlation of prodrug stability in between cell culture homogenates and human tissue homogenates.

G. Amidon, Y. Tsume, 2012, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

The Feasibility of Enzyme Targeted Activation for Amino Acid/Dipeptide Monoester Prodrugs of Floxuridine; Cathepsin D as a Potential Targeted Enzym

G. Amidon, Y. Tsume, 2012, Molecules.

The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.

G. Amidon, Y. Tsume, C. Provoda, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Human postprandial gastric emptying of 1-3-millimeter spheres.

J. Elashoff, G. Amidon, J. Meyer, 1988, Gastroenterology.

Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity

Peter Langguth, G. Amidon, P. Langguth, 2012, Biopharmaceutics & drug disposition.

Solution kinetics of a water-soluble hydrocortisone prodrug: hydrocortisone-21-lysinate.

G. Amidon, S. Pogany, K. Johnson, 1985, Journal of pharmaceutical sciences.

Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport.

B. Vig, G. Amidon, Xueqin Song, 2005, Molecular pharmaceutics.

Amino Acid Ester Prodrugs of Floxuridine: Synthesis and Effects of Structure, Stereochemistry, and Site of Esterification on the Rate of Hydrolysis

B. Vig, Ho-Chul Shin, G. Amidon, 2003, Pharmaceutical Research.

Dipeptidyl Peptidase IV as a Potential Target for Selective Prodrug Activation and Chemotherapeutic Action in Cancers

G. Amidon, Zhiqian Wu, Omri Wolk, 2014, Molecular pharmaceutics.

Improved intestinal transport of PD 158473, an N-methyl-D-aspartate (NMDA) antagonist, by involvement of multiple transporters.

Narayanan Surendran, Gordon L Amidon, Hyo-Kyung Han, 2002, Journal of pharmaceutical sciences.

Potential of Amino Acid/Dipeptide Monoester Prodrugs of Floxuridine in Facilitating Enhanced Delivery of Active Drug to Interior Sites of Tumors: A Two-Tier Monolayer In Vitro Study

G. Amidon, Y. Tsume, J. Hilfinger, 2011, Pharmaceutical Research.

Targeted delivery to PEPT1-overexpressing cells: Acidic, basic, and secondary floxuridine amino acid ester prodrugs

B. Vig, G. Amidon, Xueqin Song, 2005, Molecular Cancer Therapeutics.

Cellular Uptake Mechanism of Amino Acid Ester Prodrugs in Caco-2/hPEPT1 Cells Overexpressing a Human Peptide Transporter

G. Amidon, Hyo-Kyung Han, D. Oh, 1998, Pharmaceutical Research.

Biowaiver monographs for immediate release solid oral dosage forms: pyrazinamide.

D. Barends, G. Amidon, H. Junginger, 2008, Journal of pharmaceutical sciences.

N-METHYLPURINE DNA GLYCOSYLASE AND 8-OXOGUANINE DNA GLYCOSYLASE METABOLIZE THE ANTIVIRAL NUCLEOSIDE 2-BROMO-5,6-DICHLORO-1-(β-D-RIBOFURANOSYL)BENZIMIDAZOLE

G. Amidon, Xueqin Song, A. Brancale, 2006, Drug Metabolism and Disposition.

Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo

G. Amidon, Xueqin Song, P. Lorenzi, 2005, Journal of Pharmacology and Experimental Therapeutics.

The Mechanism of Uptake of Biodegradable Microparticles in Caco-2 Cells Is Size Dependent

Gordon L. Amidon, Robert J. Levy, R. Levy, 1997, Pharmaceutical Research.

Steady‐state pharmacokinetics of delavirdine in HIV‐positive patients: Effect on erythromycin breath test

D. E. Smith, G. Amidon, P. Watkins, 1997, Clinical pharmacology and therapeutics.

Applying the biopharmaceutics classification system to veterinary pharmaceutical products. Part II. Physiological considerations.

G. Amidon, A. Mitra, J. Riviere, 2002, Advanced drug delivery reviews.

Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated Compounds

Patrick J. Sinko, Gordon L. Amidon, G. Amidon, 2004, Pharmaceutical Research.

Predicting Fraction Dose Absorbed in Humans Using a Macroscopic Mass Balance Approach

Patrick J. Sinko, Gordon L. Amidon, G. Amidon, 1991, Pharmaceutical Research.

Physicochemical model for dose-dependent drug absorption.

G. Amidon, J. Dressman, D. Fleisher, 1984, Journal of pharmaceutical sciences.

Analysis of models for determining intestinal wall permeabilities.

G. Amidon, E. Lightfoot, R. Elliott, 1980, Journal of pharmaceutical sciences.

A convective mass transfer model for determining intestinal wall permeabilities: laminar flow in a circular tube.

G. Amidon, E. Lightfoot, R. Elliott, 1980, Journal of theoretical biology.

Calculation of the Aqueous Diffusion Layer Resistance for Absorption in a Tube: Application to Intestinal Membrane Permeability Determination

G. Amidon, D. Fleisher, J. Kou, 1991, Pharmaceutical Research.

Characterization of the Oral Absorption of β-Lactam Antibiotics. I. Cephalosporins: Determination of Intrinsic Membrane Absorption Parameters in the Rat Intestine In Situ

G. Amidon, P. Sinko, 1988, Pharmaceutical Research.

Purely in silico BCS classification: science based quality standards for the world's drugs.

G. Crippen, G. Amidon, C. Ramachandran, 2013, Molecular pharmaceutics.

Characteristics of gastrointestinal absorption of DX-9065a, a new synthetic anticoagulant.

G. Amidon, Y. Aramaki, H. Kikuchi, 2007, Drug metabolism and pharmacokinetics.

Human Jejunal Permeability of Two Polar Drugs: Cimetidine and Ranitidine

G. Amidon, L. Lesko, H. Lennernäs, 2001, Pharmaceutical Research.

Time-Dependent Oral Absorption Models

Gordon L. Amidon, Kazutaka Higaki, G. Amidon, 2001, Journal of Pharmacokinetics and Pharmacodynamics.

Human Intestinal Permeability of Piroxicam, Propranolol, Phenylalanine, and PEG 400 Determined by Jejunal Perfusion

G. Amidon, L. Lesko, H. Lennernäs, 1997, Pharmaceutical Research.

Oral Absorption of Peptides: The Effect of Absorption Site and Enzyme Inhibition on the Systemic Availability of Metkephamid

G. Amidon, H. Merkle, P. Langguth, 1994, Pharmaceutical Research.

Use of the Peptide Carrier System to Improve the Intestinal Absorption of L-α-Methyldopa: Carrier Kinetics, Intestinal Permeabilities, and In Vitro Hydrolysis of Dipeptidyl Derivatives of L-α-Methyldopa

G. Amidon, H. Mosberg, P. Subramanian, 2004, Pharmaceutical Research.

Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats.

G. Amidon, S. Yamashita, A. Ohike, 2002, Journal of pharmaceutical sciences.

Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter.

G. Amidon, X. Chu, K. Higaki, 2001, Journal of Pharmacology and Experimental Therapeutics.

Prediction of drug-drug interaction during oral absorption of carrier-mediated compounds in humans

G. Amidon, D. Oh, 1994 .

Characterization of the Oral Absorption of Some β-Lactams Effect of the α-Amino Side Chain Group

G. Amidon, P. Sinko, D. Oh, 1993 .

Characterization of the oral absorption of several aminopenicillins: determination of intrinsic membrane absorption parameters in the rat intestine in situ.

G. Amidon, P. Sinko, Oh D-M, 1992, International journal of pharmaceutics.

Predicting Oral Drug Absorption in Humans: A Macroscopic Mass Balance Approach for Passive and Carrier-Mediated Compounds

G. Amidon, P. Sinko, D. Oh, 1991 .

Intestinal absorption mechanism of dipeptide angiotensin converting enzyme inhibitors of the lysyl-proline type: lisinopril and SQ 29,852.

G. Amidon, D. Friedman, 1989, Journal of pharmaceutical sciences.

Passive and carrier-mediated intestinal absorption components of captopril.

G. Amidon, M. Hu, 1988, Journal of pharmaceutical sciences.

Improving intestinal absorption of water-insoluble compounds: a membrane metabolism strategy.

G. Amidon, G. Leesman, R. Elliott, 1980, Journal of pharmaceutical sciences.

Gastric emptying of nondigestible solids in dogs: a hydrodynamic correlation.

G. Amidon, J. Meyer, J. Dressman, 1990, The American journal of physiology.

Summary Workshop Report: Bioequivalence, Biopharmaceutics Classification System, and Beyond

Jack A. Cook, Vinod P. Shah, Lawrence X. Yu, 2008, The AAPS Journal.

Nucleoside Ester Prodrug Substrate Specificity of Liver Carboxylesterase

G. Amidon, Xueqin Song, P. Lorenzi, 2006, Journal of Pharmacology and Experimental Therapeutics.

Oral absorption of 21-corticosteroid esters: a function of aqueous stability and intestinal enzyme activity and distribution.

G. Amidon, D. Fleisher, B. H. Stewart, 1986, Journal of pharmaceutical sciences.

Uptake of prodrugs by rat intestinal mucosal cells: mechanism and pharmaceutical implications.

G. Amidon, B. H. Stewart, R. K. Brabec, 1986, Journal of pharmaceutical sciences.

Effect of micronization on the extent of drug absorption from suspensions in humans

G. Amidon, R. Curl, C. Yong, 1995 .

Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.

G. Amidon, Kyung-Dall Lee, A. Dahan, 2013, Molecular pharmaceutics.

In vitro stability and intestinal absorption characteristics of hexapeptide endothelin receptor antagonists.

G. Amidon, A. Doherty, B. H. Stewart, 1998, Life sciences.

Blockade of interleukin-6 receptor suppresses the proliferation of H460 lung cancer stem cells.

Ho-Chul Shin, G. Amidon, Soo-Min Cho, 2012, International journal of oncology.

Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs

Gordon L. Amidon, Duxin Sun, G. Amidon, 2002, Pharmaceutical Research.

Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine

Maria A. Croyle, Blake J. Roessler, Cheng-Pang Hsu, 1998, Pharmaceutical Research.

The Absence of Accessible Vitronectin Receptors in Differentiated Tissue Hinders Adenoviral-Mediated Gene Transfer to the Intestinal Epithelium In Vitro

G. Amidon, E. Walter, B. Roessler, 1997, Pharmaceutical Research.

Adenovirus mediated gene transfer to intestinal epithelial cells as a potential approach for oral delivery of peptides and proteins

G. Amidon, B. Davidson, E. Walter, 1997 .

Gastrointestinal Transport of Peptide and Protein Drugs and Prodrugs

G. Amidon, B. H. Stewart, J. Bai, 1994 .

Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.

G. Amidon, A. Dahan, 2009, American journal of physiology. Gastrointestinal and liver physiology.

The "site of action"

G. Amidon, 2005 .

Changes in mechanical events and adenosine 3',5'-monophosphate levels induced by enantiomers of isoproterenol in isolated rat atria and uteri.

G. Amidon, P. Abel, C. Buckner, 1975, The Journal of pharmacology and experimental therapeutics.

Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system

G. Amidon, M. Bermejo, I. González-Álvarez, 2018, British journal of clinical pharmacology.

The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine; an explanation for the double peak phenomenon

Gordon L. Amidon, G. Amidon, Rebecca L. Oberle, 1987, Journal of Pharmacokinetics and Biopharmaceutics.

Human Postprandial Gastric l-3-Millimeter Spheres Emptying of

J. Elashoff, G. Amidon, J. Dressman, 1988 .

Mass Balance Approaches for Estimating the Intestinal Absorption and Metabolism of Peptides and Analogues: Theoretical Development and Applications

G. Amidon, P. Sinko, G. Leesman, 1993, Pharmaceutical Research.

Dissolution and Solubility Behavior of Fenofibrate in Sodium Lauryl Sulfate Solutions

Gordon L Amidon, G. Amidon, C. Ramachandran, 2005, Drug development and industrial pharmacy.

The Use of BDDCS in Classifying the Permeability of Marketed Drugs

Vinod P. Shah, Lawrence X. Yu, James E. Polli, 2008, Pharmaceutical Research.

G.L. Amidon, H. Lennernas, V.P. Shah, and J.R. Crison. A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of In Vitro Drug Product Dissolution and In Vivo Bioavailability, Pharm Res 12, 413–420, 1995—Backstory of BCS

G. Amidon, V. Shah, 2014, The AAPS Journal.

Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs.

R. Löbenberg, G. Amidon, J. S. Kim, 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans.

S. Choe, R. Löbenberg, G. Amidon, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pharmacokinetics of the CYP 3A Substrate Simvastatin following Administration of Delayed Versus Immediate Release Oral Dosage Forms

G. Amidon, P. Langguth, P. Staubach, 2008, Pharmaceutical Research.

The fraction dose absorbed, in humans, and high jejunal human permeability relationship.

G. Amidon, H. Lennernäs, A. Dahan, 2012, Molecular pharmaceutics.

Influence of Physical Aging on Mechanical Properties of Polymer Free Films: The Prediction of Long-Term Aging Effects on the Water Permeability and Dissolution Rate of Polymer Film-Coated Tablets

G. Amidon, R. E. Robertson, Jian-Hwa Guo, 1991, Pharmaceutical Research.

The Effect of Physical Aging on the Dissolution Rate of Anionic Polyelectrolytes

G. Amidon, A. Yee, C. M. Sinko, 1990, Pharmaceutical Research.

Biowaiver monographs for immediate release solid oral dosage forms: ethambutol dihydrochloride.

D. Barends, G. Amidon, H. Junginger, 2008, Journal of pharmaceutical sciences.

Transporter and ion channel gene expression after caco-2 cell differentiation using 2 different microarray technologies

Pascale Anderle, Wolfgang Sadee, Gordon L. Amidon, 2004, The AAPS Journal.

Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract.

Jason R. Baker, G. Amidon, R. Lionberger, 2017, Molecular pharmaceutics.

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

G. Amidon, J. Brasseur, M. Bermejo, 2018, The AAPS Journal.

Utilization of Gastrointestinal Simulator, an in Vivo Predictive Dissolution Methodology, Coupled with Computational Approach To Forecast Oral Absorption of Dipyridamole.

G. Amidon, K. Matsui, Y. Tsume, 2017, Molecular pharmaceutics.

Exploring gastrointestinal variables affecting drug and formulation behavior: Methodologies, challenges and opportunities.

Roelof J Bennink, Clive G. Wilson, Bart Hens, 2017, International journal of pharmaceutics.

An Investigation into the Mechanical and Transport Properties of Aqueous Latex Films: A New Hypothesis for the Film-Forming Mechanism of Aqueous Dispersion System

G. Amidon, R. E. Robertson, Jian-Hwa Guo, 1993, Pharmaceutical Research.

Viscoelastic Properties of Polyacrylic Acid Gels in Mixed Solvents

N. Weiner, G. Amidon, J. S. Chu, 2004, Pharmaceutical Research.

Pharmacokinetics of Drugs

Gordon L. Amidon, L. Balant, G. Amidon, 1994, Handbook of Experimental Pharmacology.

Mechanism of gastrointestinal drug absorption and application in therapeutic drug delivery

R. Löbenberg, G. Amidon, N. Bou-Chacra, 2013 .

In vitro characterization of sodium glycocholate binding to cholestyramine resin.

J. Polli, G. Amidon, 1995, Journal of pharmaceutical sciences.

Gastrointestinal Motility Variation and Implications for Plasma Level Variation: Oral Drug Products.

G. Amidon, Arjang Talattof, Judy C Price, 2016, Molecular pharmaceutics.

Enteric coated aspirin circumventing gastric retention.

G. Amidon, J. Dressman, 1985, The Journal of rheumatology.

Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

G. Amidon, M. Bermejo, N. Rodríguez-Hornedo, 2019, Pharmaceutics.

G. Amidon, V. Shah, 2014, The AAPS Journal.

Bioequivalence of Oral Products and the Biopharmaceutics Classification System: Science, Regulation, and Public Policy

G. Amidon, H. Lennernäs, P. Langguth, 2011, Clinical pharmacology and therapeutics.

Enabling the intestinal absorption of highly polar antiviral agents: ion-pair facilitated membrane permeation of zanamivir heptyl ester and guanidino oseltamivir.

G. Amidon, A. Dahan, Jonathan M. Miller, 2010, Molecular pharmaceutics.

Molecular Basis of Prodrug Activation by Human Valacyclovirase, an α-Amino Acid Ester Hydrolase*

G. Amidon, Zhaohui Xu, Kyung-Dall Lee, 2008, Journal of Biological Chemistry.

Determination of the population pharmacokinetic parameters of sustained‐release and enteric‐coated oral formulations, and the suppository formulation of diclofenac sodium by simultaneous data fitting using NONMEM

G. Amidon, N. Idkaidek, N. Najib, 1998, Biopharmaceutics & drug disposition.

The Role of Rheological Properties in Mucociliary Transport by Frog Palate Ciliated Model

N. Weiner, G. Amidon, D. Fleisher, 1994, Pharmaceutical Research.

Viscoelastic properties of poly(ethylene oxide) solution.

G. Amidon, A. Goldberg, N. Weiner, 1994, Journal of pharmaceutical sciences.

The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique.

G. Amidon, L. Lesko, H. Lennernäs, 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Excess free energy approach to the estimation of solubility in mixed solvent systems II: Ethanol-water mixtures.

G. Amidon, N. A. Williams, 1984, Journal of pharmaceutical sciences.

Transport processes in pharmaceutical systems

Elizabeth M. Topp, Gordon L. Amidon, G. Amidon, 1999 .

Theoretical calculations on an acetic acid, 5-methylimidazole, methanol hydrogen bond network: a model charge relay system.

G. Amidon, 1974, Journal of theoretical biology.

Overview of membrane transport.

G. Amidon, D. Oh, 1999, Pharmaceutical biotechnology.

Membrane topology of the human dipeptide transporter, hPEPT1, determined by epitope insertions.

G L Amidon, G. Amidon, W. Sadee, 1998, Biochemistry.

Gastrointestinal Dissolution and Absorption of Class II Drugs

G. Amidon, A. Dahan, 2008 .

Rapid in vivo dissolution of ketoprofen: implications on the biopharmaceutics classification system.

G. Amidon, C. Ramachandran, G. Granero, 2006, Die Pharmazie.

Propagation Characteristics of Fasting Duodeno-Jejunal Contractions in Healthy Controls Measured by Clustered Closely-spaced Manometric Sensors

G. Amidon, J. Brasseur, K. Shedden, 2019, Journal of neurogastroenterology and motility.

The effect of enzymatic reaction on dissolution rate: theoretical analysis and experimental test.

D. A. Johnson, G. Amidon, 1986, Journal of pharmaceutical sciences.

Modulated Drug Release Using Iontophoresis through Heterogeneous Cation-Exchange Membranes: Membrane Preparation and Influence of Resin Cross-Linkage

R. Levy, G. Amidon, M. Meyerhoff, 1992 .

A theoretical model for the use of functional antagonism to estimate dissociation constants for agonists.

G. Amidon, C. Buckner, 1982, Journal of pharmacological methods.

Oral Bioavailability of Peptide and Peptidomimetic Drugs

G. Amidon, A. Dahan, Y. Tsume, 2011 .

Transporters in the GI Tract

Ho-Chul Shin, G. Amidon, Duxin Sun, 2004 .

A novel high-throughput pepT1 transporter assay differentiates between substrates and antagonists.

B. Vig, G. Amidon, T. Stouch, 2004, Molecular pharmaceutics.

Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model

R. Löbenberg, G. Amidon, M. Bermejo, 2018, The AAPS Journal.

Report of the Workshop on In Vitro and In Vivo Testing and Correlation for Oral Controlled/Modified-Release Dosage Forms

J. E. Carter, W. H. Barr, G. Amidon, 1990 .

Dissolution Effect of Gastric and Intestinal pH fora BCS class II drug, Pioglitazone: New in vitro Dissolution System to Predict in vivo Dissolution

G. Amidon, Y. Tsume, Susumu Takeuchi, 2013 .

Provisional BCS Classification of the Leading Oral Drugs on the Global Market

G. Amidon, A. Dahan, 2010, Burger's Medicinal Chemistry and Drug Discovery.

Biowaiver monographs for immediate release solid oral dosage forms: cimetidine.

D. Barends, G. Amidon, H. Junginger, 2006, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms: amitriptyline hydrochloride.

D. Barends, G. Amidon, V. Shah, 2006, Journal of pharmaceutical sciences.

Feasibility of Biowaiver Extension to Biopharmaceutics Classification System Class III Drug Products

Jennifer B Dressman, Gordon L Amidon, G. Amidon, 2006, Clinical Pharmacokinetics.

Gastric pH Influences the Appearance of Double Peaks in the Plasma Concentration-Time Profiles of Cimetidine After Oral Administration in Dogs

Gordon L. Amidon, G. Amidon, J. Dressman, 1995, Pharmaceutical Research.

Novel approach to the analysis of in vitro-in vivo relationships.

G L Amidon, J. Polli, J. Crison, 1996, Journal of pharmaceutical sciences.

Saturable small intestinal drug absorption in humans: modeling and interpretation of cefatrizine data.

G L Amidon, G. Amidon, L. Yu, 1998, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Dissolution of acidic and basic compounds from the rotating disk: influence of convective diffusion and reaction.

G L Amidon, G. Amidon, D P McNamara, 1986, Journal of pharmaceutical sciences.

The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids.

G L Amidon, G. Amidon, J. Meyer, 1990, Gastroenterology.

Celiprolol double-peak occurrence and gastric motility: Nonlinear mixed effects modeling of bioavailability data obtained in dogs

Gordon L. Amidon, Peter Langguth, Ernst Mutschler, 1995, Journal of Pharmacokinetics and Biopharmaceutics.

Variable gastric emptying and discontinuities in drug absorption profiles: Dependence of rates and extent of cimetidine absorption on motility phase and pH

G. Amidon, P. Langguth, H. Spahn‐Langguth, 1994, Biopharmaceutics & drug disposition.

Biowaiver monographs for immediate release solid oral dosage forms: Doxycycline hyclate.

D. Barends, G. Amidon, H. Junginger, 2010, Journal of pharmaceutical sciences.

Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.

Mei-Ling Chen, Guohua Zhang, Lawrence X. Yu, 2004, Journal of pharmaceutical sciences.

Estimating the Fraction Dose Absorbed from Suspensions of Poorly Soluble Compounds in Humans: A Mathematical Model

Gordon L. Amidon, G. Amidon, R. Curl, 1993, Pharmaceutical Research.

The Effect of In Vivo Dissolution, Gastric Emptying Rate, and Intestinal Transit Time on the Peak Concentration and Area-Under-the-Curve of Drugs with Different Gastrointestinal Permeabilities

Ajaz S. Hussain, William R. Gillespie, Gordon L. Amidon, 2004, Pharmaceutical Research.

Permeability and clearance views of drug absorption: A commentary

Hans Lennernäs, Gordon L. Amidon, J. Crison, 1995, Journal of Pharmacokinetics and Biopharmaceutics.

Mechanistic analysis of solute transport in an in vitro physiological two‐phase dissolution apparatus

G. Amidon, G. Amidon, Yi Shi, 2012, Biopharmaceutics & drug disposition.

Comparison of several molecular topological indexes with molecular surface area in aqueous solubility estimation.

G L Amidon, G. Amidon, S. Anik, 1976, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate-release solid oral dosage forms: codeine phosphate.

J. Polli, G. Amidon, V. Shah, 2014, Journal of pharmaceutical sciences.

In Vitro and in Vivo Testing and Correlation for Oral Controlled/Modified-Release Dosage Forms

J. E. Carter, Vinod P. Shah, Avraham Yacobi, 2004, Pharmaceutical Research.

Percutaneous absorption and dermal delivery of cyclosporin A.

G. Flynn, G. Amidon, H. K. Choi, 1995, Journal of pharmaceutical sciences.

Variability in cimetidine absorption and plasma double peaks following oral administration in the fasted state in humans: correlation with antral gastric motility.

Lawrence J Lesko, Ryuzo Yamamoto, Gordon L Amidon, 2002, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Possibility of enterohepatic recycling of ketoprofen in dogs.

G. Amidon, G. Granero, 2008, International journal of pharmaceutics.

Stereoselective Systemic Disposition of Ibuprofen Enantiomers in the Dog

G. Amidon, David E. Smith, H. Ahn, 1991, Pharmaceutical Research.

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions.

Katie L. Cavanagh, Jason R. Baker, R. Löbenberg, 2018, Molecular pharmaceutics.

Particle diffusional layer thickness in a USP dissolution apparatus II: a combined function of particle size and paddle speed.

G. Amidon, J. Dressman, P. Sirois, 2008, Journal of pharmaceutical sciences.

The H2 Receptor Antagonist Nizatidine is a P-Glycoprotein Substrate: Characterization of its Intestinal Epithelial Cell Efflux Transport

G. Amidon, A. Dahan, Hairat Sabit, 2009, The AAPS Journal.

Identification of a Human Valacyclovirase

G. Amidon, X. Chu, Kyung-Dall Lee, 2003, Journal of Biological Chemistry.

Biology of Membrane Transport Proteins

G. Amidon, W. Sadee, Volkmar Drübbisch, 1995, Pharmaceutical Research.

An improved synthesis of a fluorophosphonate–polyethylene glycol–biotin probe and its use against competitive substrates

G. Amidon, H. Showalter, Hao Xu, 2013, Beilstein journal of organic chemistry.

Physicochemical property modification strategies based on enzyme substrate specificities II: alpha-chymotrypsin hydrolysis of aspirin derivatives.

G. Amidon, P. K. Banerjee, 1981, Journal of pharmaceutical sciences.

Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.

B. Vig, G. Amidon, Xueqin Song, 2005, Molecular pharmaceutics.

Proline prodrug of melphalan, prophalan-L, demonstrates high therapeutic index in a murine melanoma model.

G. Amidon, Kyung-Dall Lee, Y. Tsume, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Mechanistic Basis of Cocrystal Dissolution Advantage.

G. Amidon, N. Rodríguez-Hornedo, G. Amidon, 2018, Journal of pharmaceutical sciences.

In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases.

Gordon L Amidon, G. Amidon, G. Amidon, 2015, Journal of pharmaceutical sciences.

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project.

James G Brasseur, Kerby Shedden, Niloufar Salehi, 2018, International journal of pharmaceutics.

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi‐compartment stomach approach

Jason R. Baker, R. Löbenberg, G. Amidon, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Lack of Interaction Between the Peptidomimetic Substrates Captopril and Cephradine

G. Amidon, C. Ramachandran, L. Welage, 2009, Journal of clinical pharmacology.

The solvent contribution to the free energy of protein--ligand interactions.

G. Amidon, R. S. Pearlman, S. Anik, 1979, Journal of theoretical biology.

Chemical Aspects of Drug Delivery Systems Edited by D. R. Karsa (Akcros Chemicals) and R. A. Stephenson. The Royal Society of Chemistry: Cambridge. 1996. viii + 161 pp. $89.00. ISBN 0-85404-706-9.

G. Amidon, 1997 .

A Proposed Pediatric Biopharmaceutical Classification System for Medications for Chronic Diseases in Children.

G. Amidon, V. Bhatt-Mehta, Hannah Hammoud, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Mixture Experimental Design in the Development of a Mucoadhesive Gel Formulation

Gordon L. Amidon, Arthur H. Goldberg, N. Weiner, 1991, Pharmaceutical Research.

Improving the intestinal mucosal cell uptake of water insoluble compounds

G. Amidon, S. Pogany, B. Stewart, 1985 .

Transmembrane transport of peptide type compounds: prospects for oral delivery.

J. Crison, G. Amidon, E. Lipka, 1996, Journal of controlled release : official journal of the Controlled Release Society.

Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group.

G. Amidon, D. Fleisher, R. Allen, 1982, Journal of pharmaceutical sciences.

Oral peptide delivery: improving the systemic availability of small peptides and enkephalin analogs.

G. Amidon, H. J. Lee, 1995, NIDA research monograph.

CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs.

G. Amidon, J. Rhie, D. Oh, 1999, Journal of pharmaceutical sciences.

A solubility equation for non-electrolytes in water

G. Amidon, N. A. Williams, 1982 .

Oral Absorption of Peptides: Influence of pH and Inhibitors on the Intestinal Hydrolysis of Leu-Enkephalin and Analogues

G. Amidon, D. Friedman, 2004, Pharmaceutical Research.

Human proton/oligopeptide transporter (POT) genes: Identification of putative human genes using bioinformatics

G. Amidon, W. Sadee, C. Nielsen, 2000, AAPS PharmSci.

Effect of biphenyl hydrolase‐like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice

G. Amidon, Y. Tsume, Jian Shi, 2018, Biochemical pharmacology.

Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization

G. Amidon, N. Rodríguez-Hornedo, G. Amidon, 2016, Molecular pharmaceutics.

Polypeptides for controlled release applications: Synthesis and preliminary characterization and release studies

G. Amidon, T. J. Cook, V. Yang, 1997 .

HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: in vitro-in vivo correlation with permeability data from rats and humans.

G. Amidon, E. Walter, B. Roessler, 1996, Journal of pharmaceutical sciences.

Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue.

G. Amidon, T. Nakanishi, I. Tamai, 2016, Journal of pharmaceutical sciences.

Protein denaturation during freezing and thawing in phosphate buffer systems: monomeric and tetrameric beta-galactosidase.

G. Amidon, N. Rodríguez-Hornedo, J. Carpenter, 2000, Archives of biochemistry and biophysics.

In Vitro Characterization of the Biomimetic Properties of Poly(dimethylsiloxane) To Simulate Oral Drug Absorption.

P. Sinko, G. Amidon, G. Amidon, 2017, Molecular pharmaceutics.

Function and immunolocalization of overexpressed human intestinal H+/peptide cotransporter in adenovirus-transduced Caco-2 cells

G. Amidon, H. Merkle, B. Rothen‐Rutishauser, 1999, AAPS PharmSci.

Dedication to Professor Leslie Z. Benet: 50 Years of Scientific Excellence and Still Going Strong!

G. Amidon, K. Giacomini, M. Rowland, 2012, Pharmaceutical Research.

First‐pass Metabolism of Peptide Drugs in Rat Perfused Liver

G. Amidon, S. Yamashita, P. Langguth, 1998, The Journal of pharmacy and pharmacology.

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

H Lennernäs, A Lindahl, A Van Peer, 2017, Molecular pharmaceutics.

MRP2 mediated drug-drug interaction: indomethacin increases sulfasalazine absorption in the small intestine, potentially decreasing its colonic targeting.

G. Amidon, A. Dahan, 2010, International journal of pharmaceutics.

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.

Kazuki Matsui, Yasuhiro Tsume, G. Amidon, 2015, Molecular pharmaceutics.

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.

G. Amidon, G. Amidon, K. Matsui, 2015, Molecular pharmaceutics.

Bio-predictive tablet disintegration: effect of water diffusivity, fluid flow, food composition and test conditions.

G. Amidon, M. Wagner, P. Langguth, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Biowaiver monographs for immediate release solid oral dosage forms: acetaminophen (paracetamol).

D. Barends, G. Amidon, H. Junginger, 2006, Journal of pharmaceutical sciences.

D. Barends, G. Amidon, H. Junginger, 2004, Journal of pharmaceutical sciences.

Mechanistic understanding of food effects: water diffusivity in gastrointestinal tract is an important parameter for the prediction of disintegration of solid oral dosage forms.

G. Amidon, M. Wagner, P. Langguth, 2013, Molecular pharmaceutics.

Ultra-Thin, Large-Area Membrane Diffusion Cell for pH-Dependent Simultaneous Dissolution and Absorption Studies.

P. Sinko, G. Amidon, G. Amidon, 2020, Molecular pharmaceutics.

Dedication to Professor Leslie Z. Benet: 50 Years of Scientific Excellence and Still Going Strong!

Malcolm Rowland, David E. Smith, Gordon L. Amidon, 2012, Pharmaceutical Research.

The Effect of Dosage Release Formulations on the Pharmacokinetics of Propranolol Stereoisomers in Humans

G. Amidon, L. Welage, M. Shea, 1995, Journal of clinical pharmacology.

Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time