K. Edlund

发表

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics*

J. Nielsen, M. Huss, C. Lindskog, 2013, Molecular & Cellular Proteomics.

The human liver‐specific proteome defined by transcriptomics and antibody‐based profiling

J. Nielsen, B. Hallström, E. Lundberg, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

B. Hallström, F. Pontén, M. Uhlén, 2015, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Impact of intratumoral heterogeneity of breast cancer tissue on quantitative metabolomics using high‐resolution magic angle spinning 1H NMR spectroscopy

J. Rahnenführer, K. Edlund, J. Hengstler, 2018, NMR in biomedicine.

Metabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway

J. Rahnenführer, K. Edlund, J. Hengstler, 2017, Analytical and Bioanalytical Chemistry.

Gene Copy Number Aberrations Are Associated with Survival in Histologic Subgroups of Non-small Cell Lung Cancer

L. Holmberg, K. Edlund, A. Andersson, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice

Christian H. Holland, U. Hofmann, S. Dooley, 2021, Hepatology communications.

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

Wolfgang Moritz, Wiebke Albrecht, Tim Brecklinghaus, 2019, Archives of Toxicology.

An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non–Small Cell Lung Cancer

Yoshimitsu Abiko, Mitsuhiro Ohshima, Johan Botling, 2014, Clinical Cancer Research.

Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?

C. Lindskog, K. Edlund, J. Mattsson, 2015, Expert review of molecular diagnostics.

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

F. Pontén, K. Edlund, K. Jirström, 2016, BMC Cancer.

Molecular Characterisation and Prognostic Biomarker Discovery in Human Non-Small Cell Lung Cancer

K. Edlund, 2012 .

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes

J. Rahnenführer, K. Edlund, O. Taboureau, 2018, Archives of Toxicology.

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

K. Edlund, W. Schmidt-Heck, D. Hay, 2015, Journal of hepatology.

The Transcriptomic and Proteomic Landscapes of Bone Marrow and Secondary Lymphoid Tissues

B. Hallström, M. Uhlén, L. Fagerberg, 2014, PloS one.

Quantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data

L. Holmberg, K. Edlund, A. Isaksson, 2009, PloS one.

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.

Alison J. Foster, Dominic P. Williams, J. Rahnenführer, 2021, Chemico-biological interactions.

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

K. Edlund, W. Schmidt-Heck, D. Hay, 2015, Journal of Hepatology.

Microdissection of well defined cell populations for RNA isolation in the analysis of normal human skin and basal cell carcinoma

K. Edlund, 2005 .

Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Mats Lambe, Jan G Hengstler, Anders Berglund, 2012, Clinical Cancer Research.

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

M. Nitsche, U. Nöthlings, S. Vieths, 2020, Archives of Toxicology.

Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells.

J. Rahnenführer, K. Edlund, N. Blüthgen, 2022, Journal of hepatology.

Tissue-based map of the human proteome

G. von Heijne, C. Lindskog, J. Mulder, 2015, Science.

In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red Assay.

J. Rahnenführer, K. Edlund, J. Hengstler, 2022, Toxicology letters.

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

J. Rahnenführer, K. Edlund, N. Blüthgen, 2022, Cells.

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

J. Rahnenführer, K. Edlund, L. Kuepfer, 2019, Archives of Toxicology.

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics.

J. Nielsen, M. Huss, C. Lindskog, 2014, Molecular & cellular proteomics : MCP.

Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer.

K. Edlund, K. Miyazono, L. Johansson, 2010, Cancer research.

CD99 is a novel prognostic stromal marker in non‐small cell lung cancer

Mats Lambe, Anders Isaksson, Fredrik Nyberg, 2012, International journal of cancer.

Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non‐small‐cell lung cancer

F. Pontén, K. Edlund, K. Jirström, 2014, International journal of cancer.

Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma

F. Pontén, K. Edlund, A. Asplund, 2008, The British journal of dermatology.

The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.

B. Hallström, F. Pontén, M. Uhlén, 2015, Omics : a journal of integrative biology.

Contribution to the ongoing discussion on fluoride toxicity

M. Nitsche, U. Nöthlings, S. Vieths, 2021, Archives of Toxicology.

The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling

B. Hallström, F. Pontén, M. Uhlén, 2014, Journal of Gastroenterology.

Targeted resequencing of candidate genes using selector probes

Magnus Isaksson, Henrik Johansson, Mats Nilsson, 2010, Nucleic Acids Res..

Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth

C. Lindskog, J. Rahnenführer, K. Edlund, 2023, Journal of Experimental & Clinical Cancer Research.

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Jan G Hengstler, Katja Ickstadt, Jörg Rahnenführer, 2017, PloS one.

Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to EGFR and KRAS Mutation Status

K. Edlund, J. Staaf, P. Micke, 2013, PloS one.

The lung‐specific proteome defined by integration of transcriptomics and antibody‐based profiling

C. Lindskog, J. Rahnenführer, B. Hallström, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma.

J. Rahnenführer, K. Edlund, J. Hengstler, 2017, Cancer research.

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

C. Lindskog, J. Rahnenführer, F. Pontén, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics

Mats Nilsson, Marco Mignardi, Johan Botling, 2013, Oncotarget.

Profiling cancer testis antigens in non-small-cell lung cancer.

Mats Lambe, Jan G Hengstler, Hans Brunnström, 2016, JCI insight.

Toxicogenomics directory of chemically exposed human hepatocytes

R. Stierum, G. Myatt, J. Rahnenführer, 2014, Archives of Toxicology.

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer

K. Edlund, F. Hirsch, H. Popper, 2017, Genes & development.

Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy

J. Rahnenführer, K. Edlund, Marcus Schmidt, 2016, PloS one.

The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer.

L. Holmberg, J. Rahnenführer, F. Pontén, 2013, Cancer letters.

KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

K. Edlund, B. Glimelius, M. Lindell, 2010, BMC Cancer.

Loss of circadian clock gene expression is associated with tumor progression in breast cancer

J. Rahnenführer, K. Edlund, Marcus Schmidt, 2014, Cell cycle.

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid Tumors

L. Holmberg, J. Rahnenführer, K. Edlund, 2012, Clinical Cancer Research.

Defining the human adipose tissue proteome to reveal metabolic alterations in obesity.

J. Nielsen, B. Hallström, F. Pontén, 2014, Journal of proteome research.

Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression.

J. Rahnenführer, F. Pontén, K. Edlund, 2015, Cancer letters.

Prognostic Influence of Pre-Operative C-Reactive Protein in Node-Negative Breast Cancer Patients

J. Rahnenführer, K. Edlund, Marcus Schmidt, 2014, PloS one.

LRIG1 is a prognostic biomarker in non-small cell lung cancer

K. Edlund, R. Henriksson, K. Jirström, 2015, Acta oncologica.

Characterisation of EGFR and KRAS mutations in non-small cell lung cancer

K. Edlund, M. Sundström, 2010 .

Impact of Thawing on RNA Integrity and Gene Expression Analysis in Fresh Frozen Tissue

Per-Uno Malmström, Johan Botling, Patrick Micke, 2009, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

F. Pontén, K. Edlund, K. Jirström, 2016, BMC Cancer.

Consistent mutation status within histologically heterogeneous lung cancer lesions

K. Edlund, J. Mattsson, P. Micke, 2012, Histopathology.

Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression

Christian H. Holland, T. Luedde, U. Hofmann, 2021, Cells.

Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

K. Edlund, U. Şahin, Marcus Schmidt, 2020, International journal of molecular sciences.

Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria.

E. Salido, P. Boor, A. Schriewer, 2021, Cell reports.

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease

R. Vadigepalli, J. Hoek, K. Edlund, 2020, Archives of Toxicology.

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

Nils Blüthgen, Reinhard Guthke, Jan G. Hengstler, 2016, Archives of Toxicology.

The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

B. Hallström, F. Pontén, M. Uhlén, 2014, PloS one.

Identification of sample annotation errors in gene expression datasets

Jan G. Hengstler, Jörg Rahnenführer, Johan Botling, 2015, Archives of Toxicology.

Marker in Human Solid Tumors C as a Compatible Prognostic κ Identifies Stromal Immunoglobulin A Comprehensive Analysis of Human Gene Expression Profiles

L. Holmberg, K. Edlund, H. Bojar, 2012 .

Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer

L. Påhlman, K. Edlund, A. Isaksson, 2015, BMC Cancer.

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

K. Edlund, C. Heldin, G. Pyrowolakis, 2015, Oncotarget.

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease

R. Vadigepalli, J. Hoek, K. Edlund, 2020, Archives of Toxicology.

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

Thierry Soussi, Ulf Gyllensten, Ola Larsson, 2012, Proceedings of the National Academy of Sciences.

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

M. Nitsche, U. Nöthlings, S. Vieths, 2020, Archives of Toxicology.

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters

J. Rahnenführer, F. Pontén, D. Djureinovic, 2017, Modern Pathology.

Gene Expression–Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial

J. Rahnenführer, K. Edlund, S. Loibl, 2021, Clinical Cancer Research.

Road Map for Development of Stem Cell-Based Alternative Test Methods.

K. Edlund, J. Hengstler, N. Hewitt, 2019, Trends in molecular medicine.

Prognostic significance of interferon regulating factor 4 (IRF4) in node-negative breast cancer

J. Rahnenführer, K. Edlund, J. Hengstler, 2017, Journal of Cancer Research and Clinical Oncology.

Identification of sample annotation errors in gene expression datasets

J. Rahnenführer, K. Edlund, Marcus Schmidt, 2015, Archives of Toxicology.

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

J. Rahnenführer, K. Edlund, N. Blüthgen, 2022, Chemical research in toxicology.

Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes

Wolfgang Moritz, Wiebke Albrecht, Tim Brecklinghaus, 2018, Archives of Toxicology.

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes

J. Rahnenführer, K. Edlund, O. Taboureau, 2018, Archives of Toxicology.

Prognostic Impact of Immunoglobulin Kappa C (IGKC) in Early Breast Cancer

J. Rahnenführer, K. Edlund, H. Joensuu, 2021, Cancers.

HR-MAS NMR Based Quantitative Metabolomics in Breast Cancer

K. Edlund, J. Hengstler, R. Hergenröder, 2019, Metabolites.

Subtype-specific prognostic impact of different immune signatures in node-negative breast cancer

J. Rahnenführer, K. Edlund, J. Hengstler, 2017, Breast Cancer Research and Treatment.

LIPG‐promoted lipid storage mediates adaptation to oxidative stress in breast cancer

A. Schriewer, J. Rahnenführer, F. Pontén, 2019, International journal of cancer.

Gelsolin Is Associated with Longer Metastasis-free Survival and Reduced Cell Migration in Estrogen Receptor-positive Breast Cancer.

Jan G Hengstler, Jörg Rahnenführer, Karolina Edlund, 2015, Anticancer research.