J. Pignon

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Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials

S. Burdett, M. Parmar, Lesley A. Stewart, 1998, The Lancet.

Investigating trial and treatment heterogeneity in an individual patient data meta‐analysis of survival data by means of the penalized maximum likelihood approach

J. Pignon, S. Michiels, V. Rondeau, 2008, Statistics in medicine.

Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program.

J. Pignon, E. Brambilla, S. Lantuejoul, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Progression-free survival is a surrogate for survival in advanced colorectal cancer.

D. Sargent, M. Buyse, J. Pignon, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[Estimation of alcohol-related deaths in France in 1985].

J. Pignon, C. Hill, 1991, Gastroenterologie clinique et biologique.

[Serum lipoproteins and alcoholic diseases of the liver].

J. Pignon, C. Lieber, E. Baraona, 1987, Gastroentérologie Clinique et Biologique.

Postoperative radiotherapy for non-small cell lung cancer.

M. Parmar, S. Burdett, R. Arriagada, 2016, The Cochrane database of systematic reviews.

Benefit of Adjuvant Chemotherapy for Resectable Gastric Cancer

Yasuo Ohashi, Junichi Sakamoto, Tomasz Burzykowski, 2009 .

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis.

M. Parmar, J. Pignon, V. Grégoire, 2017, The Lancet. Oncology.

Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group.

Richard J Stephens, Lesley Seymour, Valter Torri, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data

Caroline Domerg, Stefan Michiels, Herbert Pang, 2013, The Lancet. Oncology.

Validation of a risk-assessment scale and a risk-adapted monitoring plan for academic clinical research studies--the Pre-Optimon study.

Sylvie Chevret, Philippe Ravaud, Geneviève Chêne, 2011, Contemporary clinical trials.

Multidrug Resistance Proteins Do Not Predict Benefit of Adjuvant Chemotherapy in Patients with Completely Resected Non–Small Cell Lung Cancer: International Adjuvant Lung Cancer Trial Biologic Program

J. Pignon, E. Brambilla, H. Popper, 2007, Clinical Cancer Research.

[Individual patient data meta-analyses of randomized trials for the treatment of non-metastatic head and neck squamous cell carcinomas: Principles, results and perspectives].

J. Pignon, J. Bourhis, S. Michiels, 2015, Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique.

Efficacy and safety of bevacizumab-based combination regimens in patients with previously untreated metastatic colorectal cancer: final results from a randomised phase II study of bevacizumab plus 5-fluorouracil, leucovorin plus irinotecan versus bevacizumab plus capecitabine plus irinotecan (FNCLCC

B. Chauffert, J. Pignon, T. Conroy, 2013, European journal of cancer.

DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy.

Elisabeth Brambilla, Laure Sabatier, Robert Pirker, 2006, The New England journal of medicine.

Fatty acid‐binding protein: A major contributor to the ethanol‐induced increase in liver cytosolic proteins in the rat

J. Pignon, C. Lieber, E. Baraona, 1987, Hepatology.

Prophylactic cranial irradiation in small cell lung cancer.

R. Arriagada, J. Pignon, T. le Chevalier, 2004, Hematology/oncology clinics of North America.

Treatment outcome and survival in participants of phase I oncology trials carried out from 2003 to 2006 at Institut Gustave Roussy.

N. Magné, J. Pignon, A. Italiano, 2008, Annals of oncology : official journal of the European Society for Medical Oncology.

Effect of amifostine on survival among patients treated with radiotherapy: a meta-analysis of individual patient data.

J. Pignon, P. Levendag, J. Bourhis, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Meta-analysis of chemotherapy in head and neck cancer: individual patient data vs literature data.

J. Pignon, J. Bourhis, 1995, British Journal of Cancer.

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients.

J. Pignon, J. Bourhis, E. Maillard, 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Hyperfractionated or accelerated radiotherapy for head and neck cancer.

K. Ang, J. Horiot, J. Pignon, 2010, The Cochrane database of systematic reviews.

A Pooled Exploratory Analysis of the Effect of Tumor Size and KRAS Mutations on Survival Benefit From Adjuvant Platinum-Based Chemotherapy in Node-Negative Non–Small Cell Lung Cancer

P. Jänne, J. Pignon, L. Seymour, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site.

J. Pignon, J. Bourhis, P. Blanchard, 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Quality of Life of Patients Operated on for Low Rectal Cancer: Impact of the Type of Surgery and Patients’ Characteristics

J. Pignon, F. Zenasni, S. Dauchy, 2005, Diseases of the colon and rectum.

Chemotherapy in non-small cell lung cancer: an update of an individual patient data-based meta-analysis.

L. Stewart, S. Burdett, J. Pignon, 2005, The Journal of thoracic and cardiovascular surgery.

Angiogenesis inhibition in the second-line treatment of metastatic colorectal cancer-A definite conclusion?

J. Pignon, M. Ducreux, P. Österlund, 2017, Seminars in oncology.

Individual patient data meta-analysis in cancer.

L. Stewart, J. Pignon, M. Clarke, 1998, British Journal of Cancer.

Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials

S. Burdett, M. Parmar, R. Souhami, 1998, The Lancet.

Postoperative radiotherapy for non-small cell lung cancer.

M. Parmar, S. Burdett, R. Arriagada, 2016, The Cochrane database of systematic reviews.

Response to R. Jayaraj.

J. Pignon, P. Blanchard, A. Aupérin, 2020, Oral oncology.

Hepatic arterial infusion of oxaliplatin plus systemic chemotherapy and targeted therapy for unresectable colorectal liver metastases.

J. Pignon, M. Ducreux, V. Boige, 2020, European journal of cancer.

Randomised Trial Comparing Three Different Schedules of Infusional 5FU and Raltitrexed Alone as First-Line Therapy in Metastatic Colorectal Cancer

J. Pignon, M. Ducreux, A. Dunant, 2006, Oncology.

Cost-Effectiveness Analysis of First-Line Chemotherapies in Metastatic Colorectal Cancer

J. Pignon, M. Ducreux, O. Bouché, 2007, Oncology.

[Assessment of the cost of first line chemotherapy in metastatic colorectal cancer. Preliminary results in the FFCD 9601 trial].

J. Pignon, M. Ducreux, V. Boige, 2001, Gastroenterologie clinique et biologique.

Results of R0 Resection for Colorectal Liver Metastases Associated With Extrahepatic Disease

J. Pignon, M. Ducreux, M. Pocard, 2004, Annals of Surgical Oncology.

Extrahepatic disease does not contraindicate hepatectomy for colorectal liver metastases

J. Pignon, M. Pocard, D. Elias, 2003, The British journal of surgery.

Multicentre phase II trial of capecitabine plus oxaliplatin (XELOX) in patients with advanced hepatocellular carcinoma: FFCD 03-03 trial

J. Pignon, M. Ducreux, V. Boige, 2007, British Journal of Cancer.

Heated intra-operative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis: pharmacokinetics and tissue distribution.

J. Pignon, M. Ducreux, D. Elias, 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer.

J. Pignon, N. Saijo, M. Fukuoka, 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

Chemotherapy for colorectal cancer – Authors' reply

J. Pignon, M. Ducreux, D. Malka, 2012 .

Bevacizumab versus anti-epidermal growth factor receptor in first-line metastatic colorectal cancer. A meta-analysis: The last building block?

J. Pignon, M. Ducreux, 2016, European journal of cancer.

ANtiangiogenic Second-line Lung cancer Meta-Analysis on individual patient data in non-small cell lung cancer: ANSELMA.

H. Groen, G. Scagliotti, N. Hanna, 2022, European journal of cancer.

Individual patient data meta-analysis of neoadjuvant chemotherapy followed by surgery versus upfront surgery for carcinoma of the oesophagus or the gastro-oesophageal junction.

V. Gebski, J. Roth, Jian-Hua Fu, 2021, European journal of cancer.

Individual patient data meta-analysis of prophylactic cranial irradiation in locally advanced non-small cell lung cancer.

H. Groen, J. Pignon, D. de Ruysscher, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Meta-Analysis of Chemotherapy in Nasopharynx Carcinoma (MAC-NPC): an update on 26 trials and 7080 patients

Jun Ma, J. Pignon, G. Fountzilas, 2021, Clinical and Translational Radiation Oncology.

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19805 patients, on behalf of MACH-NC group.

B. Jeremic, L. Collette, J. Pignon, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Prognostic impact of HPV-associated p16-expression and smoking status on outcomes following radiotherapy for oropharyngeal cancer: The MARCH-HPV project.

J. Pignon, Q. Zhang, J. Overgaard, 2017, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Hepatic and Extrahepatic Colorectal Metastases: When Resectable, Their Localization Does Not Matter, But Their Total Number Has a Prognostic Effect

J. Pignon, M. Ducreux, M. Pocard, 2005, Annals of Surgical Oncology.

Syddansk Universitet Role of radiotherapy fractionation in head and neck cancers ( MARCH ) an updated meta-analysis

M. Parmar, J. Pignon, V. Grégoire, 2017 .

Individual patients' data meta-analyses in head and neck cancer

J. Pignon, J. Bourhis, A. le Maître, 2007, Current opinion in oncology.

Predictive classifier for intensive treatment of head and neck cancer

M. Parmar, J. Pignon, V. Grégoire, 2020, Cancer.

Impact of Systematic EGFR and KRAS Mutation Evaluation on Progression-Free Survival and Overall Survival in Patients with Advanced Non–Small-Cell Lung Cancer Treated by Erlotinib in a French Prospective Cohort (ERMETIC Project—Part 2)

J. Pignon, B. Chetaille, J. Solassol, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Unexpected toxicity of cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: results of the UNICANCER ACCORD 16 phase II trial.

J. Pignon, T. Conroy, E. Deutsch, 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

Impact of thoracic radiotherapy timing in limited-stage small-cell lung cancer: usefulness of the individual patient data meta-analysis.

H. Choy, R. Arriagada, J. Pignon, 2016, Annals of oncology : official journal of the European Society for Medical Oncology.

Impact of adjuvant chemotherapy (CT) on survival and local-control in non-small cell lung cancer (NSCLC): Results of the international adjuvant lung cancer trial (IALT)

R. Arriagada, J. Pignon, R. Gralla, 2004 .

Impact of primary tumour resection on survival of patients with colorectal cancer and synchronous metastases treated by chemotherapy: results from the multicenter, randomised trial Fédération Francophone de Cancérologie Digestive 9601.

J. Pignon, M. Ducreux, V. Boige, 2013, European journal of cancer.

Long-term results of the International Adjuvant Lung Cancer Trial (IALT) evaluating adjuvant cisplatin-based chemotherapy in resected non-small cell lung cancer (NSCLC)

R. Arriagada, J. Pignon, A. Dunant, 2008 .

Prognostic value of HLA-A2 status in advanced non-small cell lung cancer patients.

J. Pignon, D. Planchard, N. Chaput, 2017, Lung cancer.

Adjuvant cisplatin-based chemotherapy in nonsmall-cell lung cancer: new insights into the effect on failure type via a multistate approach.

R. Arriagada, J. Pignon, A. Dunant, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials.

J. Pignon, L. Seymour, F. Shepherd, 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

Adjuvant Cisplatin and Vinorelbine for Completely Resected Non-small Cell Lung Cancer: Subgroup Analysis of the Lung Adjuvant Cisplatin Evaluation

J. Pignon, R. Stephens, L. Seymour, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Surgery (S) and radiotherapy (RT) plus adjuvant chemotherapy (CT) versus surgery and radiotherapy in non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomised clinical trials (RCTs)

S. Burdett, J. Pignon, H. Tribodet, 2007 .

Adjuvant Therapy for Early Lung Cancer: Reflections and Perspectives

J. Pignon, C. Massard, 2006 .

PD-L1 protein expression assessed by immunohistochemistry is neither prognostic nor predictive of benefit from adjuvant chemotherapy in resected non-small cell lung cancer

J. Pignon, P. Hainaut, L. Seymour, 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

Effect of thoracic radiotherapy on mortality in limited small cell lung cancer. A meta-analysis of 13 randomized trials among 2,140 patients.

R. Souhami, R. Arriagada, J. Pignon, 1994, Anticancer research.

PL-3 Results of the randomized international adjuvant lung cancer trial (IALT): Cisplatin-based chemotherapy (CT) vs no CT in 1867 patients (PTS) with resected non-small cell lung cancer (NSCLC)

J. Pignon, R. Pirker, T. Ciuleanu, 2003 .

Should adjuvant chemotherapy become standard treatment in all patients with resected non-small-cell lung cancer?

G. Scagliotti, R. Arriagada, J. Pignon, 2005, The Lancet Oncology.

Comment on "Chemoradiotherapy regimens for locoregionally advanced nasopharyngeal carcinoma: a Bayesian network meta-analysis", published in Eur J Cancer 51 (2015), 1570-1579.

J. Pignon, P. Blanchard, Anne W. M. Lee, 2016, European journal of cancer.

Phase III trial of concurrent thoracic radiotherapy with either first- or third-cycle chemotherapy for limited-disease small-cell lung cancer.

J. Pignon, C. Le Péchoux, B. Lueza, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Comment on "Survival improvement in resectable non-small cell lung cancer with (neo)adjuvant chemotherapy: results of a meta-analysis of the literature" by T. Berghmans, M. Paesmans, A.P. Meert, C. Mascaux, P. Lothaire, J.J. Lafitte, et al. [Lung Cancer 49 (2005) 13-23.].

S. Burdett, J. Pignon, 2006, Lung cancer.

Estimating Number of Events from the Kaplan–Meier Curve for Incorporation in a Literature‐Based Meta‐Analysis: What You Don't See You Can't Get!

L. Collette, J. Pignon, L. Duchateau, 2000, Biometrics.

Role of chemotherapy in 5 000 patients with head and neck cancer treated by curative surgery: a subgroup analysis of the Meta-Analysis of Chemotherapy in Head and Neck Cancer

J. Pignon, V. Grégoire, Q. Le, 2020 .

Overall Survival in Men With Bone Metastases From Castration-Resistant Prostate Cancer Treated With Bone-Targeting Radioisotopes: A Meta-analysis of Individual Patient Data From Randomized Clinical Trials.

L. Collette, C. Parker, B. Erikstein, 2019, JAMA oncology.

Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer.

J P Pignon, J. Pignon, M. Ducreux, 2001, The New England journal of medicine.

Efficacy of adjuvant fluorouracil and folinic acid in colon cancer International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators

J. P. Pignon, Valter Torri, R. Labianca, 1995, The Lancet.

P31 Salvaging clinical trials forced to terminate early by results of external information

V. Torri, J. Pignon, S. Marsoni, 1993 .

Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer.

Bengt Bergman, Rodrigo Arriagada, Johan Vansteenkiste, 2004, The New England journal of medicine.

Adjuvant Chemotherapy for Non–Small Cell Lung Cancer: Contribution of the International Adjuvant Lung Trial

J. Pignon, A. Dunant, 2005, Clinical Cancer Research.

Second IASLC Workshop on combined Radiotherapy and Chemotherapy Modalities in Lung Cancer. Treatment evaluation.

M. Parmar, R. Arriagada, J. Pignon, 1994, Lung Cancer.

Proposal for a new section in Lung Cancer on ongoing randomized trials.

R. Arriagada, J. Pignon, 1994, Lung Cancer.

[Adjuvant chemotherapy in non-small cell lung cancer].

J. Pignon, F. André, J. Soria, 2004, Bulletin du Cancer.

Difference in Restricted Mean Survival Time for Cost-Effectiveness Analysis Using Individual Patient Data Meta-Analysis: Evidence from a Case Study

J. Pignon, O. Rivero-Arias, J. Bonastre, 2016, PloS one.

ANSELMA: ANtiangiogneic SEcond line Lung cancer Meta-Analysis in non-small cell lung cancer (NSCLC)

J. Pignon, J. Soria, B. Besse, 2016 .

Altered fractionated radiotherapy in the management of head and neck carcinomas: advantages and limitations

J. Pignon, G. Calais, J. Bourhis, 2004, Current opinion in oncology.

Non-small cell lung cancer, locally advanced

P. Lambin, S. Kozlov, I. Petersen, 2012 .

Predictive classifier for intensive treatment of head and neck cancer

M. Parmar, J. Pignon, V. Grégoire, 2020, Cancer.

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19805 patients, on behalf of MACH-NC group.

B. Jeremic, L. Collette, J. Pignon, 2016, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[Individual patient data meta-analyses in head and neck carcinoma: what have we learnt?].

J. Pignon, J. Bourhis, B. Baujat, 2005, Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique.

Meta-analysis of adjuvant chemotherapy in gastric cancer: a critical reappraisal.

J. Pignon, M. Ducreux, P. Rougier, 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

META-ANALYSIS. AUTHOR'S REPOLY

T. Peters, L. Stewart, R. Arriagada, 1993 .

Postoperative radiotherapy for non-small cell lung cancer.

M. Parmar, S. Burdett, R. Arriagada, 2016, The Cochrane database of systematic reviews.

Hyperfractionated or accelerated radiotherapy for head and neck cancer.

K. Ang, J. Horiot, J. Pignon, 2010 .

Pre-operative chemotherapy improves survival and reduces recurrence in operable non-small cell lung cancer: preliminary results of a systematic review and meta-analysis of individual patient data from 13 randomised trials

S. Burdett, J. Pignon, J. Tierney, 2011 .

Bevacizumab in patients (pts) with advanced hepatocellular carcinoma (HCC): Preliminary results of a phase II study with circulating endothelial cell (CEC) monitoring

J. Pignon, M. Ducreux, C. Dromain, 2007 .

Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as ﬁ rst-line treatment in patients with advanced non-small-cell lung cancer

J. Pignon, M. Fukuoka, A. Sandler, 2012 .

Sequential radio-chemotherapy (RT-CT) versus radiotherapy alone (RT) and concomitant RT-CT versus RT alone in locally advanced non-small cell lung cancer (NSCLC): Two meta-analyses using individual patient data (IPD) from randomised clinical trials (RCTs): A1-04

S. Burdett, J. Pignon, T. le Chevalier, 2007 .

In reply to Drs. Huncharek and Kupelnick

J. Pignon, S. Michiels, B. Baujat, 2006 .

Extensive molecular screening for hereditary non-polyposis colorectal cancer

J. Pignon, P. Rougier, J. Bénard, 2000, British Journal of Cancer.

Efficacy of chemoembolization for hepatocellular carcinomas: Experience from the gustave roussy institute and the bicetre hospital

J. Pignon, M. Ducreux, A. Roche, 1993, Journal of surgical oncology. Supplement.

Hepatic arterial infusion (HAI) of oxaliplatin plus intravenous (iv) fluorouracil (FU), leucovorin (LV), and cetuximab for first-line treatment of unresectable colorectal liver metastases (CRLM) (CHOICE): A multicenter phase II study.

J. Pignon, M. Ducreux, T. Baère, 2010 .

A data-based meta-analysis of randomised trials of chemotherapy versus best supportive care (BSC) in advanced non-small cell lung cancer (NSCLC)

M. Parmar, L. Stewart, R. Souhami, 1994 .

Radiation plus docetaxel and cisplatin in locally advanced pancreatic carcinoma: a non-comparative randomized phase II trial.

J. Pignon, T. Conroy, M. Ducreux, 2014, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis.

Satoshi Morita, Yasuo Ohashi, Junichi Sakamoto, 2013, European journal of cancer.

Efficacy of 5FU + cisplatin (FUP) compared to bolus 5FU (FU) in advanced pancreatic carcinoma (APC)

J. Pignon, M. Ychou, M. Ducreux, 1999 .

Low response rate after cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: long-term results of the UNICANCER ACCORD 16 phase II trial.

J. Pignon, T. Conroy, E. Deutsch, 2015, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Gemcitabine and oxaliplatin (GEMOX) alone or in combination with cetuximab as first-line treatment for advanced biliary cancer: Final analysis of a randomized phase II trial (BINGO).

J. Pignon, M. Ducreux, T. Greten, 2012 .

Phase III preliminary results of preoperative fluorouracil (F) and cisplatin (P) versus surgery alone in adenocarcinoma of stomach and lower esophagus (ASLE): FNLCC 94012-FFCD 9703 trial.

J. Pignon, T. Conroy, M. Ychou, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Neoadjuvant chemotherapy (NCT) in locally advanced gastric carcinoma (LAGC)

J. Pignon, M. Ducreux, P. Rougier, 1993 .

Apolipoprotein AI is a serum and tissue marker of liver fibrosis in alcoholic patients.

J. Pignon, P. Bedossa, T. Poynard, 1989, Alcoholism, clinical and experimental research.

Preliminary results of a phase II study of high-dose radiation therapy and neoadjuvant plus concomitant 5-fluorouracil with CDDP chemotherapy for patients with anal canal cancer: a French cooperative study.

J. Pignon, T. Conroy, M. Ducreux, 1997, Annals of oncology : official journal of the European Society for Medical Oncology.

A meta-analysis of individual patient data from randomized trials assessing chemotherapy with and without estramustine in patients with castration-refractory prostate cancer.

J. Pignon, A. L. Maître, S. Michiels, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Intestinal infections in patients with acquired immunodeficiency syndrome

J. Pignon, B. Régnier, J. Vildé, 1989, Digestive Diseases and Sciences.

[Value of the Cochrane Collaboration: the point of view of meta-analysis practitioner].

J. Pignon, 1996, Therapie.

[Meta-analysis of therapeutic trials. Principles, methods and critical reading].

J. Pignon, T. Poynard, 1993, La Revue du praticien.

[Meta-analysis of clinical trials].

J. Pignon, T. Poynard, 1991, Gastroenterologie clinique et biologique.

Meta-analyses of randomised clinical trials in oncology.

J. Pignon, C. Hill, 2001, The Lancet. Oncology.

Benefits of chemotherapy in head and neck cancer

J. Pignon, J. Bourhis, C. Hill, 2000, The Lancet.

Reply to D. Tural et al.

J. Pignon, J. Bourhis, P. Blanchard, 2014, Journal of Clinical Oncology.

Taxane-cisplatin-fluorouracil as induction chemotherapy in locally advanced head and neck cancers: an individual patient data meta-analysis of the meta-analysis of chemotherapy in head and neck cancer group.

Pierre Blanchard, Gilles Calais, Jean Bourhis, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Role of chemotherapy in 5000 patients with head and neck cancer treated by curative surgery: A subgroup analysis of the meta-analysis of chemotherapy in head and neck cancer.

J. Pignon, V. Grégoire, J. Bourhis, 2019, Oral oncology.

Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III trial.

J. Pignon, T. Conroy, M. Ychou, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Conventional vs modified fractionated radiotherapy. meta-analysis of radiotherapy in head & neck squamous cell carcinoma : a meta-analysis based on individual patient data

K. Ang, J. Horiot, J. Pignon, 2002 .

What Is the Best Treatment of Locally Advanced Nasopharyngeal Carcinoma? An Individual Patient Data Network Meta-Analysis.

George Fountzilas, Pierre Blanchard, Anne W M Lee, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

OC-003: What is the best treatment in nasopharyngeal carcinoma? An individual patient data network meta-analysis

Jun Ma, J. Pignon, J. Bourhis, 2015 .

Meta-analysis of chemotherapy in nasopharyngeal carcinoma (MAC-NPC): An update on 4,798 patients.

Jun Ma, J. Pignon, J. Bourhis, 2014 .

Statistics in clinical trials

J. Pignon, S. Senn, T. Poynard, 1990, The Lancet.

Chemotherapy in addition to supportive care improves survival in advanced non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data from 16 randomized controlled trials.

Jayne Tierney, Richard J Stephens, Rodrigo Arriagada, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Prognostic and predictive effects of KRAS mutation subtype in completely resected non-small cell lung cancer (NSCLC): A LACE-bio study.

P. Jänne, J. Pignon, P. Hainaut, 2012 .

Initial chemotherapeutic doses and long-term survival in limited small-cell lung cancer.

R. Arriagada, J. Pignon, T. le Chevalier, 2001, The New England journal of medicine.

Is a non-comparative meta-analysis of literature useful?

R. Arriagada, J. Pignon, 1992 .

How individual participant data meta-analyses have influenced trial design, conduct, and analysis

S. Burdett, J. Pignon, S. Shepperd, 2015, Journal of clinical epidemiology.

Mixed treatment comparison meta-analysis of altered fractionated radiotherapy and chemotherapy in head and neck cancer.

J. Pignon, J. Bourhis, C. Guihenneuc‐Jouyaux, 2011, Journal of clinical epidemiology.

Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer.

Jose Belderbos, Walter J Curran, Rodrigo Arriagada, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients.

H. Groen, B. Jeremic, R. Arriagada, 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

A multicenter blinded study evaluating EGFR and KRAS mutation testing methods in the clinical non-small cell lung cancer setting--IFCT/ERMETIC2 Project Part 1: Comparison of testing methods in 20 French molecular genetic National Cancer Institute platforms.

J. Pignon, J. Mosser, I. Bièche, 2014, The Journal of molecular diagnostics : JMD.

A joint model for the dependence between clustered times to tumour progression and deaths: A meta-analysis of chemotherapy in head and neck cancer

Virginie Rondeau, Stefan Michiels, J. Pignon, 2015, Statistical methods in medical research.

Hyperfractionated or accelerated radiotherapy in lung cancer: an individual patient data meta-analysis.

R. Arriagada, J. Pignon, S. Mandrekar, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis.

Jun Ma, J. Pignon, J. Bourhis, 2015, The Lancet. Oncology.

Interventions for the treatment of oral and oropharyngeal cancers: immunotherapy/biotherapy

H. Worthington, A. Glenny, J. Pignon, 2012 .

Is concurrent chemoradiation the standard of care for locally advanced non-small cell lung cancer? A review of guidelines and evidence

J. Pignon, C. Faivre-Finn, A. Aupérin, 2010 .

Use of Adjuvant Chemotherapy in Non-small Cell Lung Cancer in Routine Practice

J. Pignon, J. Soria, J. Trédaniel, 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Chemotherapy in non-small-cell lung cancer: an update of an individual patient data meta-analysis.

L. Stewart, S. Burdett, J. Pignon, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05.

M. Loriot, P. Beaune, D. Trégouët, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

ERCC1 isoform expression and DNA repair in non-small-cell lung cancer.

J. Pignon, E. Solary, L. Seymour, 2013, The New England journal of medicine.

Subtype Classification of Lung Adenocarcinoma Predicts Benefit From Adjuvant Chemotherapy in Patients Undergoing Complete Resection.

Gwénaël Le Teuff, Lesley Seymour, Ming-Sound Tsao, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cross-validation analysis of the prognostic significance of mucin expression in patients with resected non-small cell lung cancer treated with adjuvant chemotherapy: results from IALT, JBR.10 and ANITA.

J. Pignon, L. Seymour, F. Shepherd, 2013, Lung cancer.

LACE‐Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry‐based Biomarkers in Resected Non–small‐cell Lung Cancer

J. Pignon, L. Seymour, E. Brambilla, 2019, Clinical lung cancer.

Surrogate End Points for Overall Survival in Loco-Regionally Advanced Nasopharyngeal Carcinoma

Federico Rotolo, Li Zhang, Stefan Michiels, 2017 .

Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer.

R. Govindan, J. Pignon, L. Seymour, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.

J. Pignon, J. Soria, B. Besse, 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

Phase 2 study of frontline bortezomib in patients with advanced non-small cell lung cancer.

J. Pignon, D. Planchard, J. Soria, 2012, Lung cancer.

Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients.

J. Pignon, J. Bourhis, S. Leung, 2006, International journal of radiation oncology, biology, physics.

Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer.

J. Pignon, L. Seymour, E. Brambilla, 2018, Translational lung cancer research.

Prognostic and Predictive Effect of TP53 Mutations in Patients with Non–Small Cell Lung Cancer from Adjuvant Cisplatin–Based Therapy Randomized Trials: A LACE‐Bio Pooled Analysis

P. Jänne, J. Pignon, P. Hainaut, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy.

P. Jänne, J. Pignon, P. Hainaut, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy.

P. Jänne, J. Pignon, P. Hainaut, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

Brian O'Sullivan, Jacques Bernier, Richard Sylvester, 2006, The Lancet.

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.

D. Kerr, J. Pignon, A. González-Neira, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data

L. Stewart, S. Burdett, M. Parmar, 2010, The Lancet.

Tumour-infiltrating lymphocyte density is associated with favourable outcome in patients with advanced non-small cell lung cancer treated with immunotherapy.

J. Pignon, D. Planchard, J. Adam, 2021, European journal of cancer.

Immunogenic death of colon cancer cells treated with oxaliplatin

J. Pignon, L. Zitvogel, O. Kepp, 2010, Oncogene.

Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group.

J P Pignon, R. Arriagada, J. Pignon, 1999, The New England journal of medicine.

Docetaxel- and 5-FU-concurrent radiotherapy in patients presenting unresectable locally advanced pancreatic cancer: a FNCLCC-ACCORD/0201 randomized phase II trial's pre-planned analysis and case report of a 5.5-year disease-free survival

J. Pignon, M. Ychou, M. Ducreux, 2011, Radiation oncology.

A meta-analysis of thoracic radiotherapy for small-cell lung cancer.

J P Pignon, M. Tattersall, R. Souhami, 1992, The New England journal of medicine.

Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis.

B. Jeremic, M. Parmar, J. Pignon, 2021, The Lancet. Oncology.

MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma.

Jane J. Sohn, A. Schetter, G. Giaccone, 2010, Cancer research.

Prognostic value of neural invasion in rectal carcinoma: a multivariate analysis on 339 patients with curative resection.

J. Pignon, M. Ducreux, P. Rougier, 1995, European journal of cancer.

Pazopanib or placebo in completely resected stage I NSCLC patients: results of the phase II IFCT-0703 trial

J. Pignon, B. Milleron, J. Soria, 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

Long-term results of the international adjuvant lung cancer trial evaluating adjuvant Cisplatin-based chemotherapy in resected lung cancer.

Bengt Bergman, Rodrigo Arriagada, Robert Pirker, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Neoadjuvant chemotherapy in locally advanced gastric carcinoma--a phase II trial with combined continuous intravenous 5-fluorouracil and bolus cisplatinum.

J. Pignon, M. Ychou, M. Ducreux, 1994, European journal of cancer.

Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta analysis of chemotherapy on head and neck cancer

J. Pignon, Jean-Pierre Pignon, Christian Domenge, 2001 .

Update of MACH-NC (Meta-Analysis of Chemotherapy in Head & Neck Cancer) database focused on concomitant chemoradiotherapy

J. Pignon, J. Bourhis, C. Amand, 2004 .

Update of MACH-NC (Meta-Analysis of Chemotherapy in Head & Neck Cancer) database focused on concomitant chemoradiotherapy.

J. Pignon, J. Bourhis, C. Amand, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis.

J. Pignon, S. Michiels, J. Soria, 2004, JAMA.

LKB1/STK11 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value.

Jordi Remon, J. Pignon, D. Planchard, 2017, Lung cancer.

Efficacy, safety, and biomarkers of single-agent bevacizumab therapy in patients with advanced hepatocellular carcinoma.

J. Pignon, T. de Baère, M. Ducreux, 2012, The oncologist.

Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials †

J. Pignon, E. Van Cutsem, J. Tabernero, 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

Adjuvant chemotherapy for resected early-stage non-small cell lung cancer.

M. Kris, M. Parmar, L. Stewart, 2015, The Cochrane database of systematic reviews.

Normal serum neuron specific enolase (NSE) value after the first cycle of chemotherapy

R. Arriagada, J. Pignon, T. Chevalier, 1998, Cancer.

Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data.

J. Pignon, S. Michiels, C. Logothetis, 2007, The Lancet. Oncology.

Initial chemotherapeutic doses and survival in patients with limited small-cell lung cancer.

J P Pignon, P Chomy, R. Arriagada, 1993, The New England journal of medicine.

Gender Differences in the Response of Hepatic Fatty Acids and Cytosolic Fatty Acid-Binding Capacity to Alcohol Consumption in Rats

J. Pignon, C. Lieber, E. Baraona, 1991, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[What are the real indications for hepatectomies in metastases of colorectal origin?].

J. Pignon, B. Debaene, S. Bonvalot, 1998, Gastroenterologie clinique et biologique.

Mortality factors associated with chronic pancreatitis

J. Pignon, P. Lévy, P. Bernades, 1989 .

Mortality factors associated with chronic pancreatitis. Unidimensional and multidimensional analysis of a medical-surgical series of 240 patients.

J. Pignon, P. Lévy, P. Bernades, 1989, Gastroenterology.

French Intensive Care Society, International congress – Réanimation 2016

Paul P. Tallon, Stéphane Huot, B. Souweine, 2016, Annals of Intensive Care.

The effect of the UGT1A1*28 allele on survival after irinotecan-based chemotherapy: a collaborative meta-analysis

J. Pignon, P. Laurent-Puig, C. Punt, 2014, The Pharmacogenomics Journal.

Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial.

Pierre Michel, Bernard Denis, Pierre-Luc Etienne, 2011, The Lancet. Oncology.

Reply to S.D. Richman et al

J. Pignon, P. Laurent-Puig, V. Boige, 2011 .

Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors.

M. Buyse, J. Pignon, P. Rougier, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chemotherapy for Nasopharyngeal Carcinoma - Current Recommendation and Controversies.

J. Pignon, H. Sze, P. Blanchard, 2015, Hematology/oncology clinics of North America.

WITHDRAWN: Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease.

J. Pignon, S. Michiels, J. Soria, 2012, The Cochrane database of systematic reviews.

Role of thoracic radiotherapy in limited-stage small-cell lung cancer: quantitative review based on the literature versus meta-analysis based on individual data.

R. Arriagada, J. Pignon, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A graphical method for exploring heterogeneity in meta‐analyses: application to a meta‐analysis of 65 trials

Bertrand Baujat, Cédric Mahé, Jean-Pierre Pignon, 2002, Statistics in medicine.

Adjusting for patient selection suggests the addition of docetaxel to 5-fluorouracil–cisplatin induction therapy may offer survival benefit in squamous cell cancer of the head and neck

M. Mazumdar, J. Pignon, J. Bourhis, 2004, Anti-cancer drugs.

Prognostic value of clinicopathological parameters in head and neck squamous cell carcinoma: a prospective analysis.

J. Pignon, J. Klijanienko, F. D. De Braud, 1996, British Journal of Cancer.

Clinical Relevance of EGFR- or KRAS-mutated Subclones in Patients With Advanced Non-small-cell Lung Cancer Receiving Erlotinib in a French Prospective Cohort (IFCT ERMETIC2 Cohort - Part 2).

J. Pignon, H. Blons, G. Zalcman, 2019, Clinical lung cancer.

Prognostic value of serum fibronectin concentration in alcoholic cirrhotic patients

J. Pignon, T. Poynard, J. Chaput, 1985, Hepatology.

A phase II open-label multicenter study of gefitinib in combination with irradiation followed by chemotherapy in patients with inoperable stage III non-small cell lung cancer

J. Pignon, J. Adam, L. Lacroix, 2016, Oncotarget.

Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3

J. Pignon, C. Chouaid, E. Quoix, 2011, European Respiratory Journal.

Prognostic value of tumor mutations in radically treated locally advanced non-small cell lung cancer patients

J. Pignon, D. Planchard, J. Adam, 2017, Oncotarget.

Catalytic subunit of human telomerase reverse transcriptase is an independent predictor of survival in patients undergoing curative resection of hepatic colorectal metastases: a multicenter analysis.

T. Pawlik, J. Pignon, J. Vauthey, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer.

M. Buyse, J. Pignon, P. Rougier, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Does KRAS mutational status predict chemoresistance in advanced non-small cell lung cancer (NSCLC)?

J. Pignon, D. Planchard, J. Soria, 2014, Lung cancer.

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis.

M. Buyse, J. Pignon, R. Carlson, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Meta-analysis when only the median survival times are known: A comparison with individual patient data results

Stefan Michiels, Pascal Piedbois, Sarah Burdett, 2005, International Journal of Technology Assessment in Health Care.

Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial.

J. Pignon, M. Ducreux, T. Greten, 2014, The Lancet. Oncology.

Pooled analysis of the effect of age on adjuvant cisplatin-based chemotherapy for completely resected non-small-cell lung cancer.

Lesley Seymour, G. Scagliotti, J. Pignon, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Need for a new trial to evaluate adjuvant postoperative radiotherapy in non-small-cell lung cancer patients with N2 mediastinal involvement.

J. Pignon, B. Milleron, D. de Ruysscher, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4,584 patients.

G. Scagliotti, J. Pignon, R. Stephens, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Are Individual patient data meta-analyses still needed today in oncology? A discussion focused on Head and Neck oncology

J. Pignon, P. Blanchard, A. Aupérin, 2019, Acta oncologica.

Effect of Chemotherapy in Patients With Resected Small-Cell or Large-Cell Neuroendocrine Carcinoma

J. Pignon, D. Planchard, J. Soria, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Survival of patients with resected N2 non-small-cell lung cancer: evidence for a subclassification and implications.

J. Pignon, F. André, A. Dujon, 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Early stopping rules and long-term follow-up in phase III trials.

R. Arriagada, J. Pignon, 1994, Lung cancer.

Astro plenary: Effect of chemotherapy on locally advanced non-small cell lung carcinoma: A randomized study of 353 patients

R. Arriagada, J. Pignon, J. Douillard, 1991 .

The role of chest irradiation in small cell lung cancer.

R. Arriagada, J. Pignon, T. Chevalier, 1995, Cancer treatment and research.

Thoracic radiotherapy in small cell lung cancer: rationale for timing and fractionation

R. Arriagada, J. Pignon, T. Chevalier, 1989 .

Results of 136 curative hepatectomies with a safety margin of less than 10 mm for colorectal metastases

J P Pignon, J. Pignon, M. Ducreux, 1998, Journal of surgical oncology.

Resection of liver metastases from colorectal cancer: the real impact of the surgical margin.

J P Pignon, J. Pignon, M. Ducreux, 1998, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

ERCC1 and RRM1 in the international adjuvant lung trial by automated quantitative in situ analysis.

Zhong Zheng, Elisabeth Brambilla, Michael J Schell, 2011, The American journal of pathology.

Evaluation of Treatment Effect with Paired Failure Times in a Single-Arm Phase II Trial in Oncology

Federico Rotolo, Olivier Boucher, Stefan Michiels, 2018, Comput. Math. Methods Medicine.

Systematic review and meta-analysis of phase I/II targeted therapy combined with radiotherapy in patients with glioblastoma multiforme: quality of report, toxicity, and survival

J. Pignon, J. Soria, P. Blanchard, 2015, Journal of Neuro-Oncology.

Final results of a randomized trial comparing preoperative 5-fluorouracil (F)/cisplatin (P) to surgery alone in adenocarcinoma of stomach and lower esophagus (ASLE): FNLCC ACCORD07-FFCD 9703 trial

J. Pignon, T. Conroy, M. Ychou, 2007 .

Efficacy of combined 5-fluorouracil and cisplatinum in advanced gastric carcinomas. A phase II trial with prognostic factor analysis.

J. Pignon, M. Ychou, M. Ducreux, 1994, European journal of cancer.

The Accuracy of Clinical Staging of Stage I-IIIa Non-Small Cell Lung Cancer An Analysis Based on Individual Participant Data

H. Groen, M. Parmar, M. Tsuboi, 2018 .

Apolipoprotein AI and alcoholic liver disease

J. Pignon, T. Poynard, J. Chaput, 1986, Hepatology.

A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma.

J. Pignon, M. Ychou, M. Ducreux, 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

Review article: critical review of meta‐analyses of randomized clinical trials in hepatogastroenterology

J. Pignon, A. Aupérin, T. Poynard, 1997, Alimentary pharmacology & therapeutics.

Investigating the heterogeneity of alkylating agents’ efficacy and toxicity between sexes: A systematic review and meta‐analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study)

J.R. Anderson, U. Dirksen, J. Pignon, 2017, Pediatric blood & cancer.

Meta-Analyses of Chemotherapy in Head and Neck Cancer (MACH-NC): an update.

J. Pignon, J. Bourhis, A. le Maître, 2007, International journal of radiation oncology, biology, physics.

Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data.

Tomasz Burzykowski, Marc Buyse, Stefan Michiels, 2009, The Lancet. Oncology.

SP-010: Update of the meta-analysis of chemotherapy in head and neck cancer (MACH-NC)

J. Pignon, J. Bourhis, P. Blanchard, 2017 .

Extrapolation of Survival Curves from Cancer Trials Using External Information

Nicky J. Welton, Béranger Lueza, J. Pignon, 2016, Medical decision making : an international journal of the Society for Medical Decision Making.

Cost Effectiveness of Modified Fractionation Radiotherapy versus Conventional Radiotherapy for Unresected Non–Small-Cell Lung Cancer Patients

H. Choy, R. Arriagada, J. Pignon, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Joint model for left‐censored longitudinal data, recurrent events and terminal event: Predictive abilities of tumor burden for cancer evolution with application to the FFCD 2000–05 trial

Virginie Rondeau, Cécile Proust-Lima, Stefan Michiels, 2016, Biometrics.

Evaluation of heart murmurs in chinchillas (Chinchilla lanigera): 59 cases (1996-2009).

J. Pignon, C. Baey, J. Paul-Murphy, 2012, Journal of the American Veterinary Medical Association.

Treatment of unresectable hepatocellular carcinoma with lipiodol chemoembolization: a multicenter randomized trial. Groupe CHC.

J. Pignon, M. Ducreux, F. Gay, 1998, Journal of hepatology.

Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancer.

J. Pignon, J. Bourhis, R. Sylvester, 2001, Controlled clinical trials.

Phase II study of cisplatin and 120-hour continuous infusion of 5-fluorouracil in patients with advanced pancreatic adenocarcinoma.

J. Pignon, M. Ducreux, P. Rougier, 1993, Annals of oncology : official journal of the European Society for Medical Oncology.

Is meta-analysis a metaphysical or a scientific method?

R. Arriagada, J. Pignon, 2000, Chest.

Surrogate End Points for Overall Survival in Loco-Regionally Advanced Nasopharyngeal Carcinoma: An Individual Patient Data Meta-analysis

Federico Rotolo, Stefan Michiels, George Fountzilas, 2017, Journal of the National Cancer Institute.

Need for new powered trials to assess the role of post-operative radiotherapy for stage III non-small cell lung cancer.

R. Arriagada, J. Pignon, C. Le Péchoux, 2014, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Role of meta-analyses and of large randomized trials in the study of cancer treatments.

J. Pignon, C. Hill, A. Aupérin, 2009, Lung cancer.

Resected non-small cell lung cancer: need for adjuvant lymph node treatment? From hope to reality.

R. Arriagada, J. Pignon, C. Le Péchoux, 2003, Lung cancer.

Of scientific physicians and objective knowledge.

R. Arriagada, J. Pignon, 2002, International journal of radiation oncology, biology, physics.

Triangular test and randomized trials: practical problems in a small cell lung cancer trial.

A. Auquier, R. Arriagada, J. Pignon, 1994, Statistics in medicine.

Controversies in the management of small cell lung cancer: thoracic radiotherapy in limited disease

R. Arriagada, J. Pignon, T. Chevalier, 1993 .

Meta-analyses of randomized clinical trials: how to improve their quality?

R. Arriagada, J. Pignon, 1994, Lung cancer.

Impact of missing individual patient data on 18 meta-analyses of randomised trials in oncology: Gustave Roussy experience

J. Pignon, B. Lacas, C. Petit, 2018, BMJ Open.

Altered fractionated radiotherapy in head and neck cancer – Authors' reply

J. Pignon, J. Bourhis, A. L. Maître, 2006, The Lancet.

C3-05: Chemotherapy (CT) in addition to surgery or surgery plus radiotherapy (RT) in non-small cell lung cancer (NSCLC): Two meta-analyses using individual patient data (IPD) from randomised controlled trials (RCTs)

L. Stewart, R. Arriagada, J. Pignon, 2007 .

Disease-free survival as a surrogate for overall survival in adjuvant trials of gastric cancer: a meta-analysis.

Satoshi Morita, Yasuo Ohashi, Junichi Sakamoto, 2013, Journal of the National Cancer Institute.

Bias and precision of methods for estimating the difference in restricted mean survival time from an individual patient data meta-analysis

J. Pignon, S. Michiels, J. Bonastre, 2016, BMC Medical Research Methodology.

Induction treatment before surgery for non-small cell lung cancer.

R. Mirimanoff, J. Pignon, A. Gregor, 2003, Lung cancer.

Hyperfractionated and/or accelerated radiotherapy versus conventional radiotherapy for head and neck cancer

J. Pignon, J. Bourhis, R. Sylvester, 2000 .

Circulating innate immune markers and outcomes in treatment-naïve advanced non-small cell lung cancer patients.

J. Pignon, D. Planchard, N. Chaput, 2019, European journal of cancer.

Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.

J. Pignon, J. Soria, B. Besse, 2015 .

Abstract 2250: STK11 mutations in non-small cell lung cancer (NSCLC): descriptive analysis and prognostic significance

J. Pignon, D. Planchard, J. Soria, 2016 .

ALK amplification and crizotinib sensitivity in non-small cell lung cancer cell lines and patients report.

J. Pignon, D. Planchard, J. Soria, 2012 .

A frequentist one-step model for a simple network meta-analysis of time-to-event data in presence of an effect modifier

J. Pignon, S. Michiels, G. Le Teuff, 2021, PloS one.

What is the most effective treatment for head and neck squamous cell carcinoma? An individual patient data network meta-analysis from the MACH-NC and MARCH collaborative groups

M. Parmar, J. Pignon, V. Grégoire, 2017 .

Prediction of survival benefits from progression-free survival benefits in advanced non-small-cell lung cancer: evidence from a meta-analysis of 2334 patients from 5 randomised trials

M. Buyse, J. Pignon, V. Georgoulias, 2013, BMJ Open.

Locally advanced head and neck cancer: meta-analysis of updated individual data

J. Pignon, J. Bourhis, C. Hill, 2001 .

Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses.

J. Pignon, B. Ward, W. Pierceall, 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

Random effects survival models gave a better understanding of heterogeneity in individual patient data meta-analyses.

J P Pignon, S Michiels, B Baujat, 2005, Journal of clinical epidemiology.

Concordance measures in shared frailty models: application to clustered data in cancer prognosis

Virginie Rondeau, Audrey Mauguen, J. Pignon, 2013, Statistics in medicine.

Cetuximab plus radiochemotherapy in locally advanced anal cancer: Interim results of the French multicenter phase II trial ACCORD16.

J. Pignon, Y. Bécouarn, J. Bérille, 2011, Journal of Clinical Oncology.

The long-term impact of hyperthermic intraperitoneal chemotherapy on survivors treated for peritoneal carcinomatosis: a cross-sectional study

J. Pignon, M. Ducreux, F. Zenasni, 2009, Supportive Care in Cancer.

Ventilator-associated pneumonia and bloodstream infections in intensive care unit cancer patients: a retrospective 12-year study on 3388 prospectively monitored patients

J. Pignon, F. Rotolo, A. Stoclin, 2019, Supportive Care in Cancer.

Role of chemotherapy in patients with nasopharynx carcinoma treated with radiotherapy (MAC-NPC): an updated individual patient data network meta-analysis.

Jun Ma, J. Pignon, J. Moon, 2023, The Lancet. Oncology.

Surgery and adjuvant chemotherapy (CT) compared to surgery alone in non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomized clinical trials (RCT)

S. Burdett, J. Pignon, J. Tierney, 2007 .

Network-meta-analysis of chemotherapy in nasopharyngeal carcinoma (MAC-NPC): An update on 8,221 patients.

Jun Ma, J. Pignon, J. Bourhis, 2020 .

[Stomach adenocarcinomas: comparison between CA 19-9 and carcinoembryonic antigen for the diagnosis of recurrences after surgical treatment].

J. Pignon, M. Ychou, J. Bidart, 1992, Gastroenterologie clinique et biologique.

Progression-free survival (PFS) as a surrogate for overall survival (OS) in patients with advanced colorectal cancer: An analysis of 3159 patients randomized in 11 trials

Tomasz Burzykowski, J. P. Pignon, Kevin Carroll, 2005 .

Intra-arterial hepatic bevacizumab and systemic chemotherapy in hepatic metastasis of colorectal cancer: A phase II multicentric trial in second-line treatment.

J. Pignon, M. Ducreux, R. Guimbaud, 2022, Cancer treatment and research communications.

Postoperative hepatic arterial chemotherapy in high-risk patients as adjuvant treatment after resection of colorectal liver metastases - a randomized phase II/III trial – PACHA-01 (NCT02494973)

J. Pignon, T. de Baère, M. Ducreux, 2018, BMC Cancer.

Prognostic factors in patients with liver metastases from colorectal carcinoma treated with discontinuous intra-arterial hepatic chemotherapy.

J. Pignon, M. Ducreux, P. Rougier, 1991, European journal of cancer.

Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease.

J. Pignon, S. Michiels, J. Soria, 2007, The Cochrane database of systematic reviews.

Individual Participant Data Network Meta-Analysis of Neoadjuvant Chemotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Junction Carcinoma

V. Gebski, J. Pignon, P. Schlag, 2023, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Reply to: Is concurrent chemoradiation the standard of care for locally advanced non-small cell lung cancer? A review of guidelines and evidence.

J. Pignon, C. Faivre-Finn, A. Aupérin, 2011, Clinical oncology (Royal College of Radiologists (Great Britain)).

Clinical research infrastructures and networks in France: report on the French ECRIN workshop.

J. Pignon, C. Libersa, G. Chêne, 2005, The´rapie (Paris).

Phase I-II randomized study on prehepatectomy recombinant interleukin-2 immunotherapy in patients with metastatic carcinoma of the colon and rectum.

J. Pignon, P. Rougier, B. Escudier, 1995, Journal of the American College of Surgeons.

Prognostic evaluation in cirrhosis

J. Pignon, J. Villeneuve, C. Infante-Rivard, 1988, Hepatology.

Circulating endothelial cells (CEC) and angiogenic proteins monitoring in patients (pts) with advanced hepatocellular carcinoma (HCC) treated with bevacizumab.

J. Pignon, M. Ducreux, C. Dromain, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis.

D. Sargent, M. Buyse, J. Pignon, 2010, JAMA.

[Treatment of gastroesophageal reflux: analysis of randomized double-blind trials].

J. Pignon, G. Sebag, T. Poynard, 1987, Gastroenterologie clinique et biologique.

Surgical pathology of adenocarcinoma arising in Barrett's esophagus. Analysis of 67 cases.

J. Pignon, F. Paraf, J. Fléjou, 1995, The American journal of surgical pathology.

Adenocarcinoma of the Vater's ampulla and von Recklinghausen disease.

J. Pignon, P. Bedossa, F. Paraf, 1987, Annals of internal medicine.

Is primary tumour resection associated with survival improvement in patients with colorectal cancer and unresectable synchronous metastases? A pooled analysis of individual data from four randomised trials.

J. Pignon, M. Ducreux, J. Douillard, 2015, European journal of cancer.

Individual patient data network meta-analysis using either restricted mean survival time difference or hazard ratios: is there a difference? A case study on locoregionally advanced nasopharyngeal carcinomas

J. Pignon, P. Blanchard, C. Petit, 2019, Systematic Reviews.

Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma.

J. Pignon, J. Bourhis, S. Leung, 2006, The Cochrane database of systematic reviews.

Nasopharyngeal carcinomas: an update.

J. Pignon, J. Bourhis, J. Armand, 2003, European journal of cancer.

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data.

S. Burdett, M. Parmar, R. Souhami, 2010 .

Meta-analyses in head and neck squamous cell carcinoma. What is the role of chemotherapy?

J. Pignon, J. Bourhis, J. Bourhis, 1999, Hematology/oncology clinics of North America.

Postoperative radiotherapy for non-small cell lung cancer.

M. Parmar, S. Burdett, R. Arriagada, 2016, The Cochrane database of systematic reviews.

The Accuracy of Clinical Staging of Stage I-IIIa Non-Small Cell Lung Cancer

H. Groen, M. Parmar, M. Tsuboi, 2018, Chest.

3025 Prognostic value of PDL1 expression in stage III Non-Small Cell Lung Cancer (NSCLC) treated by chemo-radiotherapy (CRT)

J. Pignon, D. Planchard, J. Adam, 2015 .

Pazopanib (P) or placebo in completely resected stage I NSCLC patients: Survival results of the phase II trial IFCT-0703.

J. Pignon, B. Milleron, J. Soria, 2015 .

D3-03: IALT-Bio: a challenging research to improve adjuvant chemotherapy of completely resected NSCLC

J. Pignon, E. Brambilla, H. Popper, 2007 .

Taking into account successive treatment lines in the analysis of a colorectal cancer randomised trial.

S Michiels, J. Pignon, M. Ducreux, 2013, European journal of cancer.

Quality of life and cost of strategies of two chemotherapy lines in metastatic colorectal cancer: results of the FFCD 2000-05 trial

J. Pignon, M. Ducreux, C. Lepage, 2019, Expert review of pharmacoeconomics & outcomes research.

Cost Effectiveness of Modified Fractionation Radiotherapy versus Conventional Radiotherapy for Unresected Non–Small-Cell Lung Cancer Patients

H. Choy, R. Arriagada, J. Pignon, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Low response rate after cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: long-term results of the UNICANCER ACCORD 16 phase II trial.

J. Pignon, T. Conroy, Y. Bécouarn, 2015, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

ERCC1 isoform expression and DNA repair in non-small-cell lung cancer.

J. Pignon, E. Solary, L. Seymour, 2013, The New England journal of medicine.

J. Pignon, V. Boige, D. Malka, 2013, European journal of cancer.

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.

D. Kerr, J. Pignon, A. González-Neira, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

K. Ang, J. Horiot, J. Pignon, 2006, The Lancet.

Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data.

M. Buyse, J. Pignon, T. Pajak, 2009, The Lancet. Oncology.

Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages IIIa and IIIb nonsmall cell lung cancer: A meta‐analysis