J. McMurray

发表

On modeling peptidomimetics in complex with the SH2 domain of Stat3

Lydia E. Kavraki, Ankur Dhanik, John S. McMurray, 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Structural basis for the binding of high affinity phosphopeptides to Stat3

J. McMurray, 2008, Biopolymers.

Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3.

J. McMurray, P. Mandal, Z. Ren, 2009, Journal of medicinal chemistry.

Investigation of the binding determinants of phosphopeptides targeted to the SRC homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor.

Arlin G. Cameron, J. McMurray, P. Mandal, 2005, Journal of medicinal chemistry.

Solid Phase Synthesis of Phosphopeptides Incorporating 2,2-Dimethyloxazolidine Pseudoproline Analogs: Evidence for trans Leu-Pro Peptide Bonds in Stat3 Inhibitors

J. McMurray, Z. Ren, Xiaomin Chen, 2007, International Journal of Peptide Research and Therapeutics.

Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.

R. Bast, J. McMurray, P. Mandal, 2011, Journal of medicinal chemistry.

Conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription. 3: Evaluation and molecular modeling.

J. Briggs, J. McMurray, P. Mandal, 2009, Journal of medicinal chemistry.

Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity.

L. Kavraki, A. Dhanik, J. McMurray, 2015, Journal of medicinal chemistry.

DINC: A new AutoDock-based protocol for docking large ligands

L. Kavraki, A. Dhanik, J. McMurray, 2013, BMC Structural Biology.

Binding Modes of Peptidomimetics Designed to Inhibit STAT3

L. Kavraki, A. Dhanik, J. McMurray, 2012, PloS one.

Contribution of an active site cation-pi interaction to the spectroscopic properties and catalytic function of protein tyrosine kinase Csk.

J. McMurray, Xiaofeng Lin, Gongqin Sun, 2002, Biochemistry.

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012, Philadelphia, USA, October 4-7, 2012

Pablo Moscato, Giovanni De Micheli, Wenqi You, 2012, BIBM Workshops.

The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer

Li Li, Wei Xu, Ann H. Klopp, 2013, PloS one.

Molecular and pharmacological blockade of the EP4 receptor selectively inhibits both proliferation and invasion of human inflammatory breast cancer cells.

J. McMurray, F. Robertson, M. Cristofanilli, 2008, Journal of experimental therapeutics & oncology.

Fragmentation and sequencing of cyclic peptides by matrix-assisted laser desorption/ionization post-source decay mass spectrometry.

J. McMurray, K. Medzihradszky, B. Schilling, 1999, Rapid communications in mass spectrometry : RCM.

Effect of autophosphorylation on the catalytic and regulatory properties of protein tyrosine kinase Src.

Wei Wang, Latha Ramdas, Weiqi Wang, 2002, Archives of biochemistry and biophysics.

Δ24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization

W. Yung, C. Miller, J. McMurray, 2005, Cancer Gene Therapy.

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13

J. McMurray, P. Mandal, Hongbo Hu, 2014 .

STAT3 restrains RANK- and TLR4-mediated signaling by suppressing expression of the E2 ubiquitin ligase Ubc13

J. McMurray, P. Mandal, Hongbo Hu, 2014, Nature Communications.

Convenient solid-phase synthesis of diethylenetriaminepenta-acetic acid (DTPA)- conjugated cyclic RGD peptide analogues.

J. McMurray, M. Campbell, Chun Xing Li, 2005, Cancer biotherapy & radiopharmaceuticals.

A Novel C2H2 Transcription Factor that Regulates gliA Expression Interdependently with GliZ in Aspergillus fumigatus

T. Hughes, M. Weirauch, J. McMurray, 2014, PLoS genetics.

Batf is important for IL-4 expression in T follicular helper cells

J. McMurray, R. Nurieva, C. Haymaker, 2015, Nature Communications.

Crystal structure of unphosphorylated STAT3 core fragment.

J. McMurray, P. Mandal, Z. Ren, 2008, Biochemical and biophysical research communications.

Cyclic peptides as probes of the substrate binding site of the cytosolic tyrosine kinase, pp60c-src.

J. McMurray, L. Ramdas, R. J. Budde, 1998, Archives of biochemistry and biophysics.

Structural bases of unphosphorylated STAT1 association and receptor binding.

J. Darnell, J. McMurray, Z. Ren, 2005, Molecular cell.

Long-Acting Beta Agonists Enhance Allergic Airway Disease

J. McMurray, P. Mandal, D. Corry, 2015, PloS one.

Biochemical and Cellular Specificity of Peptide Inhibitors of G Protein-Coupled Receptor Kinases

J. McMurray, Richard A. Hammitt, J. Friedman, 2014, International Journal of Peptide Research and Therapeutics.

The use of polyacrylamide‐based peptide synthesis resins for the generation of antipeptide antibodies

J. McMurray, 1998, Biopolymers.

A Simple and Convenient Method for the Preparation of Ketomethylene Peptide Analogues

J. McMurray, D. Dyckes, 1985 .

Solid-phase synthesis of (tyrosyl-alanyl-glutamyl)n by segment condensation.

J. McMurray, R. J. Budde, D. Dyckes, 2009, International journal of peptide and protein research.

Pd-C-induced catalytic transfer hydrogenation with triethylsilane.

J. McMurray, P. Mandal, 2007, The Journal of organic chemistry.

Hydrodehalogenation of Alkyl Iodides with Base-Mediated Hydrogenation and Catalytic Transfer Hydrogenation: Application to the Asymmetric Synthesis of N-Protected α-Methylamines

J. McMurray, P. Mandal, J. S. Birtwistle, 2014, The Journal of organic chemistry.

The synthesis of ‘tyrosyl’ peptidomimetics by acid-catalyzed N(1)–C(4) ring opening of 4-(4′-hydroxyphenyl)-azetidine-2-ones

J. McMurray, P. Mandal, L. Cabell, 2005 .

Cleavage of the N(1)C(4) bond of 4-(4′-hydroxyphenyl)-azetidine-2-ones via quinone methide intermediates

J. McMurray, L. Cabell, L. W. Hedrich, 2001 .

Solid Phase Synthesis of Phosphorylated Cis and Trans 3-Peptidyl-4-(4′-hydroxyphenyl)-β-Lactams

J. McMurray, K. Kaluarachchi, D. R. Coleman, 2006 .

Two-carbon ring expansion of β-lactams via N(1)C(4) cleavage reactions

J. McMurray, L. Cabell, 2002 .

Influence of solid support, solvent and coupling reagent on the head-to-tail cyclization of resin-bound peptides.

J. McMurray, N. Obeyesekere, C. A. Lewis, 1994, Peptide research.

Solid phase synthesis of a cyclic peptide using fmoc chemistry

J. McMurray, 1991 .

Differential regulation of the aggressive phenotype of inflammatory breast cancer cells by prostanoid receptors EP3 and EP4

Sukhen Ghosh, Massimo Cristofanilli, J. McMurray, 2010, Cancer.

The synthesis of cyclic peptides using fmoc solid-phase chemistry and the linkage agent 4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid

J. McMurray, C. A. Lewis, 1993 .

Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer.

W. Woodward, J. McMurray, P. Mandal, 2017, International journal of radiation oncology, biology, physics.

Targeting SH2 domains in breast cancer.

John S McMurray, J. McMurray, F. Robertson, 2014, Future medicinal chemistry.

Evidence for hemiketals as intermediates in the inactivation of serine proteinases with halomethyl ketones.

J. McMurray, D. Dyckes, 1986, Biochemistry.

Large-pore polydimethylacrylamide resin for solid-phase peptide synthesis: applications in Fmoc chemistry.

J. McMurray, J. Sparrow, N. G. Knieb-Cordonier, 1996, Peptide research.

The synthesis of phosphopeptides.

J. McMurray, M. Campbell, Wen Wang, 2001, Biopolymers.

Notch activation inhibits AML growth and survival: a potential therapeutic approach

J. McMurray, A. Melnick, L. Golfman, 2013, The Journal of experimental medicine.

Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas

Nipun A. Mistry, J. Weinstein, Xifeng Wu, 2016, PloS one.

Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.

J. McMurray, C. Mullighan, Guangchun Song, 2011, Blood.

Discovery, development, and testing of substrates and inhibitors of pp60c-SRC

J. McMurray, H. Saya, V. Levin, 1995 .

Use of synthetic peptides and copolymers to study the substrate specificity and inhibition of the protein tyrosine kinase pp60c-src.

J. McMurray, R. J. Budde, S. Ke, 1995, Biochimica et biophysica acta.

Cyclic peptide substrates of pp60c-src. Synthesis and evaluation.

J. McMurray, R. J. Budde, D. Dyckes, 2009, International journal of peptide and protein research.

Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells

J. McMurray, P. Mandal, G. Klein, 2017, Oncogene.

An assay for acidic peptide substrates of protein kinases.

J. McMurray, R. J. Budde, D. A. Tinker, 1992, Analytical biochemistry.

Convenient preparation of 4-(tetrazol-5-yl)-phenylalanine for use in Fmoc-based solid-phase peptide synthesis

J. McMurray, J. S. Birtwistle, Wen Wang, 2000 .

Stereospecific synthesis of 4-carboxyphenylalanine and derivatives for use in Fmoc-based solid-phase peptide synthesis

J. McMurray, Wei Wang, N. Obeyesekere, 1996 .

A SIMPLE AND CONVENIENT METHOD FOR THE PREPARATION OF KETOMETHYLENE PEPTIDE ANALOGS

J. McMurray, D. Dyckes, 1985 .

Enhanced phagocytosis activity of cyclic analogs of tuftsin.

J. McMurray, K. Nishioka, N. Obeyesekere, 1995, Biochemical pharmacology.

A tyrphostin-derived inhibitor of protein tyrosine kinases: isolation and characterization.

J. McMurray, L. Ramdas, G. Gallick, 1995, Archives of biochemistry and biophysics.

Src Family Protein-tyrosine Kinases Alter the Function of PTEN to Regulate Phosphatidylinositol 3-Kinase/AKT Cascades*

Yiling Lu, Gordon B. Mills, John S. McMurray, 2003, Journal of Biological Chemistry.

Alteration of the erythrocyte glutathione redox balance by N‐acetylcysteine, captopril and exogenous glutathione

J. McMurray, C. Spickett, I. Abdullah, 1994, FEBS letters.

STAT3 signaling in cancer: Small molecule intervention as therapy?

J. McMurray, J. Klostergaard, 2014 .

Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma

J. McMurray, Jefferson K. Chen, V. Gandhi, 2015, Oncotarget.

Inflammatory Mediators as Therapeutic Targets for Inflammatory Breast Cancer

E. Petricoin, L. Liotta, J. McMurray, 2012 .

The consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domain

J. McMurray, P. Mandal, W. Liao, 2012, JAK-STAT.

A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.

R. Bast, J. McMurray, P. Mandal, 2012, Journal of experimental therapeutics & oncology.

Role for the Regulator of G-Protein Signaling Homology Domain of G Protein-Coupled Receptor Kinases 5 and 6 in β2-Adrenergic Receptor and Rhodopsin Phosphorylation

O. Lichtarge, H. Yao, J. McMurray, 2010, Molecular Pharmacology.

A selective method for the preparation of primary amides: Synthesis of Fmoc-L-4 carboxamidophenylalanine and other compounds

J. McMurray, Wei Wang, Wei Wang, 1999 .

N-myristoylation of a peptide substrate for Src converts it into an apparent slow-binding bisubstrate-type inhibitor.

J. McMurray, L. Ramdas, G. Sun, 1999, The journal of peptide research : official journal of the American Peptide Society.

1997 ABRF Peptide synthesis research committee study on a peptide containing a phosphorylated tyrosine

J. McMurray, L. Bonewald, K. Medzihradszky, 2002 .

Study on the synthesis and characterization of peptides containing phosphorylated tyrosine.

J. McMurray, L. Bonewald, K. Medzihradszky, 1999, The journal of peptide research : official journal of the American Peptide Society.

A new small-molecule Stat3 inhibitor.

J. McMurray, 2006, Chemistry & biology.

Small molecule targeting of the STAT5/6 Src homology 2 (SH2) domains to inhibit allergic airway disease

J. McMurray, P. Mandal, Pietro Morlacchi, 2018, The Journal of Biological Chemistry.

Solid-phase synthesis of Stat3 inhibitors incorporating O-carbamoylserine and O-carbamoylthreonine as glutamine mimics.

J. McMurray, P. Mandal, Z. Ren, 2007, Bioorganic & medicinal chemistry letters.

Identification of a high-affinity phosphopeptide inhibitor of Stat3.

J. McMurray, Z. Ren, L. Cabell, 2003, Bioorganic & medicinal chemistry letters.

Structure–Activity Studies of Phosphopeptidomimetic Prodrugs Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3 (Stat3)

J. McMurray, P. Mandal, Z. Ren, 2012, International Journal of Peptide Research and Therapeutics.

Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150.

J. McMurray, Z. Ren, Xiaomin Chen, 2009, Journal of molecular biology.

Phosphotyrosyl peptides targeted to the SH2 domain are potent inhibitors of the kinase activity of pp60c-src

J. McMurray, L. Ramdas, R. J. Budde, 2002 .

Structural basis for the activity of pp60(c-src) protein tyrosine kinase inhibitors.

J. McMurray, B. Pettitt, N. Prabhu, 2001, Biopolymers.

Tight‐binding inhibitory sequences against pp60 c−src identified using a random 15‐amino‐acid peptide library

J. McMurray, H. Saya, R. J. Budde, 1996, FEBS letters.

Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells.

J. McMurray, P. Mandal, F. Robertson, 2011, Bioorganic & medicinal chemistry letters.

Inhibition of Stat3 by cell-permeable peptidomimetic prodrugs targeted to its SH2 domain.

J. McMurray, P. Mandal, Z. Ren, 2009, Advances in experimental medicine and biology.

Targeting Gelatinases with a Near-Infrared Fluorescent Cyclic His-Try-Gly-Phe Peptide

J. McMurray, C. Charnsangavej, F. Lang, 2009, Molecular Imaging and Biology.

A solubilisable polymer support suitable for solid phase peptide synthesis and for injection into experimental animals

P. Emson, J. McMurray, R. Sheppard, 1988 .

Influence of acidic residues on substrate specificity of oncogene products pp60v-src and p56lck in vitro.

J. McMurray, V. Levin, J. Cartron, 1992, Anticancer Research.

Analysis of racemization during "Standard" solid phase peptide synthesis: a multicenter study

W. T. Moore, R. Angeletti, J. McMurray, 1997 .

Carbamazepine and SIADH.

J. McMurray, J. Mccreery, H. Hunt, 1989, The American journal of psychiatry.

Synthesis and in Vitro Evaluation of a Peptidomimetic Inhibitor Targeting the Src Homology 2 (SH2) Domain of STAT6.

J. McMurray, P. Mandal, Pietro Morlacchi, 2014, ACS medicinal chemistry letters.

Auto dock-based incremental docking protocol to improve docking of large ligands

Lydia E. Kavraki, Ankur Dhanik, John S. McMurray, 2012, 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops.

Synthesis of phosphatase-stable, cell-permeable peptidomimetic prodrugs that target the SH2 domain of Stat3.

J. McMurray, P. Mandal, W. Liao, 2009, Organic letters.

Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.

J. McMurray, P. Mandal, Z. Ren, 2011, Journal of medicinal chemistry.

Probing for Integrin αvβ3 Binding of RGD Peptides Using Fluorescence Polarization

Wei Wang, C. Li, J. McMurray, 2005 .

Model of intermolecular interactions between high affinity phosphopeptides and Stat3.

J. McMurray, P. Mandal, Z. Ren, 2009, Advances in experimental medicine and biology.

The degree of inhibition of protein tyrosine kinase activity by tyrphostin 23 and 25 is related to their instability.

J. McMurray, L. Ramdas, R. J. Budde, 1994, Cancer Research.

Formation of a Disulfide Bond in an Octreotide-Like Peptide: A Multicenter Study

W. T. Moore, R. Angeletti, J. McMurray, 1996 .