Hua Yu

发表

The STATs of cancer — new molecular targets come of age

Hua Yu, R. Jove, 2004, Nature Reviews Cancer.

Tumour immunology: Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment

Hua Yu, M. Kortylewski, D. Pardoll, 2007, Nature Reviews Immunology.

Role of Stat3 in Regulating p53 Expression and Function

Hua Yu, R. Jove, Meijuan Huang, 2005, Molecular and Cellular Biology.

Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma

Hua Yu, R. Jove, J. Homsi, 2009, Melanoma research.

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

L. Ellis, J. Turkson, D. Coppola, 2002, Oncogene.

STATs in cancer inflammation and immunity: a leading role for STAT3

Hua Yu, R. Jove, D. Pardoll, 2009, Nature Reviews Cancer.

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

Hua Yu, Andreas Herrmann, Hua Yu, 2014, Nature Reviews Cancer.

Knockdown of lncRNA MALAT1 attenuates acute myocardial infarction through miR-320-Pten axis.

Hua Yu, Likun Ma, Hao Hu, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis

A. Riggs, Yate-Ching Yuan, Hua Yu, 2019, Nucleic acids research.

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.

Hua Yu, Hong Xin, Minwei Ye, 2009, Cancer cell.

Breaking through a Plateau in Renal Cell Carcinoma Therapeutics: Development and Incorporation of Biomarkers

Hua Yu, R. Figlin, Hua Yu, 2010, Molecular Cancer Therapeutics.

Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells

Hua Yu, A. Herrmann, P. Chu, 2019, Oncogene.

Advances in gene therapy for malignant melanoma.

Hua Yu, D. Pardoll, S. Antonia, 2002, Cancer control : journal of the Moffitt Cancer Center.

Dissociation of Mitogen-activated Protein Kinase Activation from the Oxidative Burst in Differentiated HL-60 Cells and Human Neutrophils (*)

Hua Yu, R. Jove, R. Nairn, 1995, The Journal of Biological Chemistry.

Interleukin-12 cDNA skin transfection potentiates human papillomavirus E6 DNA vaccine-induced antitumor immune response

Hua Yu, H. Maassab, A. Chang, 1999, Cancer Gene Therapy.

STAT3 in CD8+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 Axis

Hua Yu, Wenzhao Li, S. Priceman, 2015, Cancer Immunology Research.

Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells

Hua Yu, Senlin Xu, Eryun Zhang, 2022, Nature communications.

Effects of calcitriol on the growth of PANC-1 cell line with vitamin D receptor ( VDR ) gene silencing

Hua Yu, Qiyu Zhang, Ke Sun, 2016 .

Imatinib attenuates myocardial fibrosis in association with inhibition of the PDGFRα activity.

Hua Yu, Likun Ma, Hao Hu, 2012, Arquivos brasileiros de cardiologia.

Inhibition of protein phosphatase 5 (PP5) suppresses survival and growth of colorectal cancer cells

Hua Yu, Xiaoyun Dai, Jinhui Zhu, 2015, Biotechnology and applied biochemistry.

Knockdown of Tripartite Motif Containing 24 by Lentivirus Suppresses Cell Growth and Induces Apoptosis in Human Colorectal Cancer Cells

Hua Yu, Xiaoyun Dai, Jinhui Zhu, 2014, Oncology research.

Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL

Hua Yu, D. Pardoll, A. Ashkenazi, 2004, Cancer Research.

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Hua Yu, Xiwei Wu, M. Muschen, 2017, Nature Communications.

Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids.

S. Hanash, Hua Yu, Chunyan Zhang, 2022, Cell reports.

Long noncoding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy modulation.

Hua Yu, Likun Ma, Hao Hu, 2020, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Long non-coding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy inhibition by regulating TSC2-mTOR signaling

Hua Yu, Likun Ma, Hao Hu, 2019, Biological Research.

CAMK2γ in Intestinal Epithelial Cells Modulates Colitis-Associated Colorectal Carcinogenesis via Enhancing STAT3 Activation

Hua Yu, Z. Meng, J. Shively, 2017, Oncogene.

Influences of rosuvastatin on the expression of matrix metallopeptidase 9 (MMP-9) through extracellular- signal-regulated kinases (ERK) pathway in mononuclear cell line (THP-1) derived macrophages induced by oxidized low density lipoprotein

Hua Yu, Qian Zhang, Kangyu Chen, 2013 .

A Novel Anti-Cancer Therapy: CRISPR/Cas9 Gene Editing

C. Pilarsky, Hua Yu, Jian-ye Zhang, 2022, Frontiers in Pharmacology.

Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis

Hua Yu, A. Placzek, F. Crawford, 1999, Journal of Neuroimmunology.

Gene gun application in the generation of effector T cells for adoptive immunotherapy

Hua Yu, A. Chang, B. Nickoloff, 2000, Cancer Immunology, Immunotherapy.

Anti-CD40 Antibody Induces Antitumor and Antimetastatic Effects: The Role of NK Cells1

Hua Yu, L. Burdelya, A. Rakhmilevich, 2001, The Journal of Immunology.

Antimetastatic Effects: The Role of NK Cells Anti-CD40 Antibody Induces Antitumor and

Hua Yu, A. Rakhmilevich, P. Sondel, 2000 .

Cell-Free DNA: Hope and Potential Application in Cancer

Hua Yu, Jian-ye Zhang, Feng-hua Wang, 2021, Frontiers in Cell and Developmental Biology.

Chinese herbal formula, Bing De Ling, enhances antitumor effects and ameliorates weight loss induced by 5-fluorouracil in the mouse CT26 tumor model.

Hua Yu, Qing Xu, Shumin M. Zhang, 2005, DNA and cell biology.

Arginyl-glutamine dipeptide attenuates experimental colitis by enhancing antioxidant function and inhibiting nuclear factor-kappaB

Hua Yu, Xiaoyun Dai, N. He, 2015 .

Bcl-xL inhibits apoptosis and necrosis produced by Alzheimer's β-amyloid1–40 peptide in PC12 cells

Hua Yu, A. Placzek, T. Town, 1999, Neuroscience Letters.

Corrigendum: Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

D. Coppola, Hua Yu, R. Jove, 2004, Nature Network Boston.

B7-H3 Associated with Tumor Progression and Epigenetic Regulatory Activity in Cutaneous Melanoma

Hua Yu, D. Morton, Jinhua Wang, 2013, The Journal of investigative dermatology.

[Studies on mechanism of myricetin-induced apoptosis in human hepatocellular carcinoma HepG-2 cells].

Hua Yu, Yubin Ji, Yun Ling, 2010, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Downregulation of RTN1-C attenuates MPP+-induced neuronal injury through inhibition of mGluR5 pathway in SN4741 cells

Hua Yu, Jiang Chang, Xiao-Le Zhang, 2019, Brain Research Bulletin.

Enhanced adjuvant effect of granulocyte-macrophage colony-stimulating factor plus interleukin-12 compared with either alone in vaccine-induced tumor immunity

Hua Yu, A. Chang, A. Aruga, 1999, Cancer Gene Therapy.

Tumor and Stem Cell Biology LossofAndrogenReceptorExpressionPromotesaStem-like Cell Phenotype in Prostate Cancer through STAT3 Signaling

Hua Yu, R. Jove, S. Pal, 2014 .

Akt inhibitors in clinical development for the treatment of cancer

R. Figlin, Hua Yu, S. Pal, 2010, Expert opinion on investigational drugs.

Sphingosine-1-Phosphate Receptor-1 Promotes Environment-Mediated and Acquired Chemoresistance

Hua Yu, Y. DeClerck, Wenzhao Li, 2017, Molecular Cancer Therapeutics.

Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-κB-Independent Mechanism

Hua Yu, L. Cui, Zhangfeng Zhong, 2017, Front. Pharmacol..

Antitumor Activity of Targeting Src Kinases in Endothelial and Myeloid Cell Compartments of the Tumor Microenvironment

Hua Yu, R. Jove, Y. Yen, 2010, Clinical Cancer Research.

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

R. Weichselbaum, Hua Yu, N. Hübner, 2017, Nature.

Microbiota-derived SSL6 enhances the sensitivity of hepatocellular carcinoma to sorafenib by down-regulating glycolysis.

Hua Yu, X. Zhang, Lei Wu, 2020, Cancer letters.

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.

Hua Yu, R. Jove, A. Herrmann, 2009, Cancer cell.

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

Hua Yu, Tianhong Wang, Maciej Kujawski, 2005, Nature Medicine.

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

Hua Yu, Domenico Coppola, Tianhong Wang, 2004, Nature Medicine.

Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM

Hua Yu, Yangyang Xie, Binbin Xu, 2021, Bioengineered.

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

Hua Yu, Yuan Yuan, Rahul Jandial, 2018, Cell metabolism.

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

Hua Yu, Yuan Yuan, Rahul Jandial, 2018, Cell metabolism.

Critical role of STAT3 in IL-6-mediated drug resistance in human neuroblastoma.

S. Groshen, Hua Yu, R. Jove, 2013, Cancer research.

TLR9 is critical for glioma stem cell maintenance and targeting.

G. Gallia, Hua Yu, R. Jove, 2014, Cancer research.

Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53

Hua Yu, Wen-xian Zhu, Jiong-jiong Lu, 2019, Cell Death & Differentiation.

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

A. Riggs, Hua Yu, R. Jove, 2012, Proceedings of the National Academy of Sciences.

Inhibition of Bcr–Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells

Hua Yu, R. Jove, Jie Wu, 2002, Oncogene.

Signal Transducer and Activator of Transcription 3 Is Required for Hypoxia-Inducible Factor-1α RNA Expression in Both Tumor Cells and Tumor-Associated Myeloid Cells

Hua Yu, R. Jove, M. Kortylewski, 2008, Molecular Cancer Research.

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment.

C. Drake, Hua Yu, M. Kortylewski, 2009, Cancer cell.

A critical role for Stat3 signaling in immune tolerance.

Hua Yu, Shizuo Akira, S. Akira, 2003, Immunity.

Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma

Jia-Bin Huang, Hua Yu, H. Xin, 2013, PloS one.

S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

R. Figlin, Hua Yu, R. Jove, 2012, Cancer cell.

COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis

Hua Yu, Charles D. Warden, Yate-Ching Yuan, 2013, Nucleic acids research.

STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth.

Hua Yu, A. Herrmann, P. Chu, 2019, Cell metabolism.

Prognostic Significance of B-Cells and pSTAT3 in Patients with Ovarian Cancer

Hua Yu, S. Pal, S. Forman, 2013, PloS one.

Metabolic reprogramming and AMPKα1 pathway activation by caulerpin in colorectal cancer cells.

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2017, International journal of oncology.

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

G. Semenza, J. Turkson, J. Cheng, 2005, Oncogene.

Molecular Cloning and Characterization of the Human AKT1 Promoter Uncovers Its Up-regulation by the Src/Stat3 Pathway*

S. Nicosia, J. Cheng, Hua Yu, 2005, Journal of Biological Chemistry.

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

Hua Yu, M. Kortylewski, D. Pardoll, 2009, The Journal of experimental medicine.

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.

Hua Yu, C. Loddenkemper, A. Herrmann, 2011, Cancer cell.

STAT Proteins as Molecular Targets for Cancer Therapy

Hua Yu, R. Jove, M. Kortylewski, 2003 .

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

Hua Yu, R. Jove, A. Chang, 2002, Oncogene.

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis

Hua Yu, D. Ann, A. Herrmann, 2021, JCI insight.

Curcumin Regulates the Progression of Colorectal Cancer via LncRNA NBR2/AMPK Pathway

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2019, Technology in cancer research & treatment.

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Hua Yu, R. Jove, G. Niu, 2001, Oncogene.

Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells.

R. Figlin, Hua Yu, A. Herrmann, 2009, Cancer research.

Stat3 as a potential target for cancer immunotherapy.

Hua Yu, M. Kortylewski, 2007, Journal of immunotherapy.

Targeting STAT3 affects melanoma on multiple fronts

Hua Yu, R. Jove, M. Kortylewski, 2005, Cancer and Metastasis Reviews.

Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling.

Hua Yu, R. Jove, G. Müller-Newen, 2014, Cancer research.

Stat3-induced S1PR1 expression is critical for persistent Stat3 activation in tumors

Hua Yu, R. Jove, A. Herrmann, 2010, Nature Medicine.

Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy.

Hua Yu, A. Herrmann, M. Kortylewski, 2009, Cancer research.

Lymphocytes and Isogenic Multidrug-Resistant Myeloma Cells: The Role of Cytotoxic T Cytokine-Based Tumor Cell Vaccine Is Equally Effective Against Parental

Hua Yu, W. Dalton, A. Shtil, 2010 .

Alternative Pathways of Cell Death to Circumvent Pleiotropic Resistance in Myeloma Cells: Role of Cytotoxic T-Lymphocytes

Hua Yu, W. Dalton, A. Shtil, 2000, Leukemia & lymphoma.

Diagnostic value of circulating miR-155 , miR-21 , and miR-10 b as promising biomarkers in human breast cancer

Hua Yu, Cen Jiang, Yibing Peng, 2016 .

Sunitinib Induces Apoptosis and Growth Arrest of Medulloblastoma Tumor Cells by Inhibiting STAT3 and AKT Signaling Pathways

Hua Yu, Fan Yang, H. Xin, 2010, Molecular Cancer Research.

Characterizing and Modulating the Tumor Microenvironment in Renal Cell Carcinoma: Potential Therapeutic Strategies

R. Figlin, Hua Yu, S. Pal, 2012 .

Therapeutics , Targets , and Chemical Biology TLR 9 Is Critical for Glioma Stem Cell Maintenance and Targeting

G. Gallia, Hua Yu, R. Jove, 2014 .

G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells*

Hua Yu, R. Jove, Chunyan Zhang, 2013, The Journal of Biological Chemistry.

S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma.

Hua Yu, A. Scuto, Yong Liu, 2012, Blood.

Tumor and Stem Cell Biology LossofAndrogenReceptorExpressionPromotesaStem-like Cell Phenotype in Prostate Cancer through STAT 3 Signaling

Hua Yu, R. Jove, A. Herrmann, 2014 .

1 Loss of Androgen Receptor Expression Promotes a Stem-Like Cell Phenotype in Prostate Cancer through STAT 3 Signaling

Hua Yu, R. Jove, G. Müller-Newen, 2013 .

The long noncoding RNA TPTE2P1 promotes the viability of colorectal cancer cells

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2018, Journal of cellular biochemistry.

CTLA4 Promotes Tyk2-STAT3-Dependent B-cell Oncogenicity.

Hua Yu, A. Herrmann, T. Blankenstein, 2017, Cancer research.

CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.

Hua Yu, R. Jove, H. Xin, 2016, Immunity.

IL-17 enhances tumor development in carcinogen-induced skin cancer.

Hua Yu, D. Pardoll, T. Yi, 2010, Cancer research.

Deciphering the anticancer mechanisms of sunitinib

R. Figlin, Hua Yu, S. Pal, 2010, Cancer biology & therapy.

Advances in Brief Gene Therapy with Dominant-negative Stat 3 Suppresses Growth of the Murine Melanoma B 16 Tumor in Vivo 1

M. Jaroszeski, D. Coppola, Hua Yu, 1999 .

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively‐activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells

Yate-Ching Yuan, Hua Yu, R. Jove, 2013, Molecular oncology.

Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone.

D. Coppola, Hua Yu, R. Jove, 2002, Molecular cancer therapeutics.

Advances in Brief Overexpression of a Dominant-Negative Signal Transducer and Activator of Transcription 3 Variant in Tumor Cells Leads to Production of Soluble Factors That Induce Apoptosis and Cell Cycle Arrest 1

Hua Yu, R. Jove, Meijuan Huang, 2001 .

Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

Hua Yu, Marek Wloch, Roy Garcia, 1997, Oncogene.

An effective cell-penetrating antibody delivery platform.

Hua Yu, A. Herrmann, Chunyan Zhang, 2019, JCI insight.

B Cells Promote Tumor Progression via STAT3 Regulated-Angiogenesis

Hua Yu, D. Hoon, S. Pal, 2013, PloS one.

MicroRNA-155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL

Hua Yu, Ling Zhou, Jun-yi Chen, 2017, Experimental and therapeutic medicine.

Next-Generation qPCR for the High-Throughput Measurement of Gene Expression in Multiple Leukocyte Subsets

Hua Yu, S. Soper, M. Murphy, 2013, Journal of biomolecular screening.

STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma.

Hua Yu, R. Jove, A. Scuto, 2011, Cancer research.

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Hua Yu, Xiwei Wu, M. Muschen, 2017, Nature Communications.

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

Hua Yu, Drew M. Pardoll, John J. Rossi, 2009, Nature Biotechnology.

JAK/STAT Signaling in Myeloid Cells

Hua Yu, R. Jove, S. Priceman, 2013 .

Chapter 26 – JAK/STAT Signaling in Myeloid Cells: Targets for Cancer Immunotherapy

Hua Yu, R. Jove, S. Priceman, 2013 .

S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3.

Hua Yu, S. Priceman, Lin Wang, 2014, Cell reports.

Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2017, Medical science monitor : international medical journal of experimental and clinical research.

STAT3: a target to enhance antitumor immune response.

R. Figlin, Hua Yu, S. Pal, 2011, Current topics in microbiology and immunology.

S 1 PR 1 is an effective target to block STAT 3 signaling in activated B cell – like diffuse large B-cell lymphoma

Hua Yu, A. Scuto, Yong Liu, 2012 .

Phosphorylation of LIFR promotes prostate cancer progression by activating the AKT pathway.

Hua Yu, Yunbo Qiao, Wencheng Zhu, 2019, Cancer letters.

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.

J. Turkson, Hua Yu, R. Jove, 2004, Molecular cancer therapeutics.

Erratum: JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance (Cell Metabolism (2018) 27(1) (136–150.e5)(S1550413117306691)(10.1016/j.cmet.2017.11.001))

Hua Yu, Yuan Yuan, Rahul Jandial, 2018 .

PARP Inhibition Activates STAT3 in Both Tumor and Immune Cells Underlying Therapy Resistance and Immunosuppression In Ovarian Cancer

Hua Yu, Chunyan Zhang, Jieun Song, 2021, Frontiers in Oncology.

Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

A. Riggs, Hua Yu, R. Jove, 2013, Proceedings of the National Academy of Sciences.

Methylation of Stat1 promoter can contribute to squamous cell carcinogenesis.

Hua Yu, Heehyoung Lee, 2006, Journal of the National Cancer Institute.

Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480.

R. Figlin, Hua Yu, R. Jove, 2011, Cancer research.

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice.

Hua Yu, A. Herrmann, M. Kortylewski, 2008, The Journal of clinical investigation.

STAT3 and Src Signaling in Melanoma

Hua Yu, S. Priceman, G. Cherryholmes, 2012 .

CD8+ T‐cell immunosurveillance constrains lymphoid premetastatic myeloid cell accumulation

Hua Yu, A. Herrmann, Chunyan Zhang, 2015, European journal of immunology.

Cutting Edge: An In Vivo Requirement for STAT3 Signaling in TH17 Development and TH17-Dependent Autoimmunity1

Hua Yu, Drew M. Pardoll, Charles G. Drake, 2007, The Journal of Immunology.

A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors.

Hua Yu, D. Pardoll, H. Xin, 2011, Cancer research.

CD44 in Ovarian Cancer Progression and Therapy Resistance—A Critical Role for STAT3

Hua Yu, Chunyan Zhang, L. Rodriguez-Rodriguez, 2020, Frontiers in Oncology.

Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice.

Hua Yu, Z. Meng, Wendong Huang, 2012, Journal of hepatology.

Role of Stat3 in suppressing anti-tumor immunity.

Hua Yu, M. Kortylewski, 2008, Current opinion in immunology.

TLR agonist–Stat3 siRNA conjugates: cell-specific gene silencing and enhanced antitumor immune responses

Hua Yu, R. Jove, A. Scuto, 2009, Nature biotechnology.

TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo.

Hua Yu, M. Kortylewski, J. Rossi, 2013, Blood.

CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells.

Hua Yu, A. Herrmann, M. Kortylewski, 2015, The Journal of clinical investigation.

CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells.

Hua Yu, A. Herrmann, M. Kortylewski, 2014, The Journal of clinical investigation.

Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects.

R. Figlin, Hua Yu, A. Scuto, 2010, Cancer research.

STAT3 activation in tumor cell-free lymph nodes predicts a poor prognosis for gastric cancer.

Hua Yu, Jun Zhang, Hai-Xia Li, 2014, International journal of clinical and experimental pathology.

Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice

Hua Yu, M. Kortylewski, B. Badie, 2009, Glia.

STAT3 nuclear egress requires exportin 7 via engaging lysine acetylation

Hua Yu, R. Jove, A. Herrmann, 2014 .

Activated stat-3 in melanoma.

Hua Yu, R. Jove, P. Munster, 2008, Cancer control : journal of the Moffitt Cancer Center.

Activated Stat3 in Melanoma

Hua Yu, R. Jove, P. Munster, 2008 .

Stat3 Activity in Melanoma Cells Affects Migration of Immune Effector Cells and Nitric Oxide-Mediated Antitumor Effects1

Hua Yu, B. Zhong, Sheng Wei, 2005, The Journal of Immunology.

Nitric Oxide-Mediated Antitumor Effects Migration of Immune Effector Cells and Stat3 Activity in Melanoma Cells Affects

Hua Yu, Sheng Wei, D. Pardoll, 2005 .

Myeloid Clusters Are Associated with a Pro-Metastatic Environment and Poor Prognosis in Smoking-Related Early Stage Non-Small Cell Lung Cancer

R. Figlin, Hua Yu, S. Pal, 2013, PloS one.

Knockdown of lncRNA KCNQ1OT1 inhibits glioma progression by regulating miR-338-3p/RRM2

Hua Yu, Y. Liu, Wenxu Zhao, 2020 .

miR-15a-3p affects the proliferation, migration and apoptosis of lens epithelial cells

Hua Yu, Ning Li, Yuanbin Li, 2018, Molecular medicine reports.

Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity

Melissa J. Davis, S. Tsuriel, S. Hediyeh-zadeh, 2021, Cancer Research.

A Requirement of STAT 3 DNA Binding Precludes Th1 Immunostimulatory Gene Expression by NFk B in Tumors

Hua Yu, D. Pardoll, H. Xin, 2011 .

Microenvironment and Immunology Antiangiogenic and Antimetastatic Activity of JAK Inhibitor AZD 1480

R. Figlin, Hua Yu, R. Jove, 2011 .

STAT 3 Inhibition Is a Therapeutic Strategy for ABC-like Diffuse Large B-Cell Lymphoma

Hua Yu, R. Jove, A. Scuto, 2011 .

Reduced IL‐6 levels and tumor‐associated phospho‐STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo‐inositol

S. Hanash, I. Wistuba, Hua Yu, 2018, International journal of cancer.

Differences in lipidomics may be potential biomarkers for early diagnosis of pancreatic cancer

Hua Yu, Ling Zhou, Xianwei Zhang, 2020, Acta cirurgica brasileira.

Long non-coding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy inhibition by regulating TSC2-mTOR signaling

Hua Yu, Likun Ma, Hao Hu, 2019, Biological Research.

Activated Signal Transducers and Activators of Transcription 3 Signaling Induces CD46 Expression and Protects Human Cancer Cells from Complement-Dependent Cytotoxicity

Hua Yu, R. Jove, Meijuan Huang, 2007, Molecular Cancer Research.

Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro.

Hua Yu, Yitao Wang, W. Qiang, 2017, Oncology reports.

Clinical and Translational Assessment of VEGFR1 as a Mediator of the Premetastatic Niche in High-Risk Localized Prostate Cancer

R. Figlin, N. Agarwal, C. Lau, 2015, Molecular Cancer Therapeutics.

Interferon-γ-inducing factor elicits antitumor immunity in association with interferon-γ production

Hua Yu, A. Chang, B. Crucian, 1998 .

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis

Hua Yu, R. Jove, Fan Yang, 2012, Cancer biology & therapy.

Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

Hua Yu, Y. Pang, Wenming Li, 2007, Journal of proteome research.

Knockdown of tetraspanin 13 inhibits proliferation of colorectal cancer cells

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2017 .

Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.

M. Jaroszeski, D. Coppola, Hua Yu, 1999, Cancer research.

Signal Transducers and Activators of Transcription: Novel Targets for Anticancer Therapeutics.

Hua Yu, R. Jove, W. Dalton, 1999, Cancer control : journal of the Moffitt Cancer Center.

Knockdown of stromal interaction molecule 1 inhibits proliferation of colorectal cancer cells by inducing apoptosis

Hua Yu, Yangyang Xie, Xiaoyun Dai, 2018, Oncology letters.