C. Barbas

发表

De Novo Computational Design of Retro-Aldol Enzymes

Eric A. Althoff, Jasmine L. Gallaher, D. Baker, 2008, Science.

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

C. Barbas, B. Tan, Y. Ishihara, 2014 .

Deoxyribose-5-phosphate aldolase as a synthetic catalyst

Chi-Huey Wong, C. Barbas, Chi‐Huey Wong, 1990 .

Prodrug activation gated by a molecular "OR" logic trigger.

Richard A Lerner, Roey J. Amir, R. Lerner, 2005, Angewandte Chemie.

Antibody-catalyzed asymmetric intramolecular Michael addition of aldehydes and ketones to yield the disfavored cis-product.

R. Lerner, C. Barbas, D. Shabat, 2005, Journal of the American Chemical Society.

Organocatalysis lost: modern chemistry, ancient chemistry, and an unseen biosynthetic apparatus.

C. Barbas, 2008, Angewandte Chemie.

A highly enantioselective amino acid-catalyzed route to functionalized α-amino acids

C. Barbas, A. Córdova, G. Zhong, 2002 .

A Highly Enantioselective Route to Either Enantiomer of Both α- and β-Amino Acid Derivatives

F. Tanaka, C. Barbas, A. Córdova, 2002 .

The direct organocatalytic asymmetric mannich reaction: unmodified aldehydes as nucleophiles.

F. Tanaka, C. Barbas, J. M. Turner, 2003, The Journal of organic chemistry.

Direct organocatalytic asymmetric Mannich-type reactions in aqueous media: one-pot Mannich-allylation reactions

C. Barbas, A. Córdova, 2003 .

A way to highly enantiomerically enriched aza-Morita-Baylis-Hillman-type products.

F. Tanaka, C. Barbas, N. Utsumi, 2007, Angewandte Chemie.

A short enantioselective synthesis of 1-deoxy-l-xylulose by antibody catalysis

R. Lerner, C. Barbas, B. List, 1999 .

Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2.

C. Barbas, R. Lerner, C. Barbas, 1999, Organic letters.

Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor

R. Lerner, F. Tanaka, C. Barbas, 1999 .

Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy†

R. Lerner, F. Tanaka, C. Barbas, 1999 .

Reconstructing Aldolase Antibodies to Alter Their Substrate Specificity and Turnover

R. Lerner, F. Tanaka, C. Barbas, 2000 .

Selective arylthiolane deprotection by singlet oxygen: a promising tool for sensors and prodrugs.

C. Barbas, B. M. Lamb, 2015, Chemical communications.

Enzyme Catalysis in Synthetic Carbohydrate Chemistry

Richard L. Pederson, C. Barbas, Chi‐Huey Wong, 1991 .

Organocatalytic asymmetric assembly reactions: one-pot synthesis of functionalized beta-amino alcohols from aldehydes, ketones, and azodicarboxylates.

C. Barbas, D. Ramachary, N. Chowdari, 2003, Organic letters.

Proline-catalyzed asymmetric assembly reactions: enzyme-like assembly of carbohydrates and polyketides from three aldehyde substrates

C. Barbas, D. Ramachary, A. Córdova, 2002 .

COFACTOR-INDUCED REFINEMENT OF CATALYTIC ANTIBODY ACTIVITY : A METAL-SPECIFIC ALLOSTERIC EFFECT

Richard A. Lerner, R. Lerner, C. Barbas, 1998 .

Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde.

F. Tanaka, C. Barbas, N. Mase, 2004, Chemical communications.

A search for peptide ligase: cosolvent-mediated conversion of proteases to esterases for irreversible synthesis of peptides

C. Barbas, Chi‐Huey Wong, J. Matos, 1988 .

Biochemical characterization and structural analysis of a highly proficient cocaine esterase.

R. Lerner, I. Wilson, C. Barbas, 2002, Biochemistry.

Direct organocatalytic aldol reactions in buffered aqueous media.

C. Barbas, A. Córdova, W. Notz, 2002, Chemical communications.

Proline-catalyzed one-step asymmetric synthesis of 5-hydroxy-(2E)-hexenal from acetaldehyde.

C. Barbas, A. Córdova, W. Notz, 2002, The Journal of organic chemistry.

Selection of phage-displayed peptides that bind to a particular ligand-bound antibody.

Arthur J Olson, Richard A Lerner, R. Fuller, 2008, Bioorganic & medicinal chemistry.

Towards organo-click chemistry: development of organocatalytic multicomponent reactions through combinations of aldol, Wittig, Knoevenagel, Michael, Diels-Alder and Huisgen cycloaddition reactions.

C. Barbas, D. Ramachary, Dhevalapally B. Ramachary, 2004, Chemistry.

Core-structure-motivated design of a phosphine-catalyzed [3+2] cycloaddition reaction: enantioselective syntheses of spirocyclopenteneoxindoles.

C. Barbas, N. Candeias, B. Tan, 2011, Journal of the American Chemical Society.

Fluorescent detection of carbon-carbon bond formation.

F. Tanaka, C. Barbas, Rajeswari Thayumanavan, 2003, Journal of the American Chemical Society.

Single-triggered trimeric prodrugs.

R. Lerner, C. Barbas, D. Shabat, 2005, Angewandte Chemie.

Mimicking dihydroxy acetone phosphate-utilizing aldolases through organocatalysis: a facile route to carbohydrates and aminosugars.

C. Barbas, D. Ramachary, J. Suri, 2005, Organic letters.

Molecular Cloning of Aldolases for Synthetic Applications a

Richard L. Pederson, G. Whitesides, C. Barbas, 1990, Annals of the New York Academy of Sciences.

Organocatalysis lost: modern chemistry, ancient chemistry, and an unseen biosynthetic apparatus.

C. Barbas, 2008, Angewandte Chemie.

Mimicking fructose and rhamnulose aldolases: organocatalytic syn-aldol reactions with unprotected dihydroxyacetone.

F. Tanaka, C. Barbas, S. Ramasastry, 2007, Angewandte Chemie.

Formylbenzene diazonium hexafluorophosphate reagent for tyrosine-selective modification of proteins and the introduction of a bioorthogonal aldehyde.

C. Barbas, W. Hakamata, M. Nagano, 2012, Bioconjugate chemistry.

Chemoenzymic Synthesis of Chiral Furan Derivatives: Useful Building Blocks for Optically Active Structures

C. Barbas, Chi‐Huey Wong, M. Ciufolini, 1988 .

Organocatalytic direct asymmetric aldol reactions in water.

F. Tanaka, C. Barbas, Y. Nakai, 2006, Journal of the American Chemical Society.

Enzyme Catalysis in Synthetic Carbohydrate Chemistry

Richard L. Pederson, C. Barbas, Chi‐Huey Wong, 1991 .

anti-Selective SMP-catalyzed direct asymmetric Mannich-type reactions: synthesis of functionalized amino acid derivatives

C. Barbas, A. Córdova, 2002 .

Towards organocatalytic polyketide synthases with diverse electrophile scope: trifluoroethyl thioesters as nucleophiles in organocatalytic Michael reactions and beyond.

C. Barbas, S. Kitagaki, D. Alonso, 2008, Angewandte Chemie.

Direct amino acid-catalyzed asymmetric desymmetrization of meso-compounds: tandem aminoxylation/O-N bond heterolysis reactions.

C. Barbas, D. Ramachary, Dhevalapally B. Ramachary, 2005, Organic letters.

Direct organocatalytic asymmetric heterodomino reactions: the Knoevenagel/Diels-Alder/epimerization sequence for the highly diastereoselective synthesis of symmetrical and nonsymmetrical synthons of benzoannelated centropolyquinanes.

C. Barbas, D. Ramachary, N. Chowdari, 2004, The Journal of organic chemistry.

Organocatalytic asymmetric domino knoevenagel/diels-alder reactions: a bioorganic approach to the diastereospecific and enantioselective construction of highly substituted spiro[5,5]undecane-1,5,9-triones.

C. Barbas, D. Ramachary, N. Chowdari, 2003, Angewandte Chemie.

Highly enantioselective organocatalytic α-amination reactions of aryl oxindoles: developing designer multifunctional alkaloid catalysts.

C. Barbas, C. Milite, Gloria Hernández-Torres, 2010, Organic letters.

Direct asymmetric alpha-fluorination of aldehydes.

C. Barbas, N. Mase, D. Steiner, 2005, Angewandte Chemie.

Enamine-based organocatalysis with proline and diamines: the development of direct catalytic asymmetric Aldol, Mannich, Michael, and Diels-alder reactions.

F. Tanaka, C. Barbas, W. Notz, 2004, Accounts of chemical research.

Amino alcohol catalyzed direct asymmetric aldol reactions: enantioselective synthesis of anti-α-fluoro-β-hydroxy ketones

C. Barbas, G. Zhong, Jun-hua Fan, 2004 .

Organocatalytic amidation and esterification of aldehydes with activating reagents by a cross-coupling strategy.

C. Barbas, B. Tan, N. Toda, 2012, Angewandte Chemie.

Efficient Aldolase Catalytic Antibodies That Use the Enamine Mechanism of Natural Enzymes

R. Lerner, C. Barbas, C F Barbas, 1995, Science.

Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine.

F. Tanaka, C. Barbas, Kaori Watanabe, 2006, Journal of the American Chemical Society.

Proline-Catalyzed Direct Asymmetric Aldol Reactions

Richard A. Lerner, R. Lerner, C. Barbas, 2000 .

Asymmetric Synthesis of Quaternary α- and β-Amino Acids and β-Lactams via Proline-Catalyzed Mannich Reactions with Branched Aldehyde Donors

C. Barbas, N. Chowdari, and Jeff T. Suri, 2004 .

Catalytic enantioselective direct Michael additions of ketones to alkylidene malonates

C. Barbas, J. M. Betancort, Rajeswari Thayumanavan, 2001 .

Antibody-Catalyzed Enantioselective Robinson Annulation

Richard A. Lerner, R. Lerner, C. Barbas, 1997 .

Rapid fluorescent screening for bifunctional amine-acid catalysts: efficient syntheses of quaternary carbon-containing aldols under organocatalysis.

F. Tanaka, C. Barbas, N. Mase, 2003, Organic letters.

Highly efficient hydrogen-bonding catalysis of the Diels-Alder reaction of 3-vinylindoles and methyleneindolinones provides carbazolespirooxindole skeletons.

C. Barbas, B. Tan, Gloria Hernández-Torres, 2011, Journal of the American Chemical Society.

Development of small designer aldolase enzymes: catalytic activity, folding, and substrate specificity.

R. Fuller, F. Tanaka, C. Barbas, 2005, Biochemistry.

Phage display selection of peptides possessing aldolase activity

F. Tanaka, C. Barbas, 2001 .

Amino acid catalyzed direct asymmetric aldol reactions: a bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions.

C. Barbas, K Sakthivel, W Notz, 2001, Journal of the American Chemical Society.

Catalytic direct asymmetric Michael reactions: taming naked aldehyde donors.

C. Barbas, J. M. Betancort, Juan M. Betancort and, 2001, Organic letters.

Dihydroxyacetone variants in the organocatalytic construction of carbohydrates: mimicking tagatose and fuculose aldolases.

F. Tanaka, C. Barbas, S. Mitsumori, 2006, The Journal of organic chemistry.

Amine-catalyzed direct self Diels–Alder reactions of α,β-unsaturated ketones in water: synthesis of pro-chiral cyclohexanones

C. Barbas, D. Ramachary, N. Chowdari, 2002 .

Amine-catalyzed direct Diels-Alder reactions of α, β-unsaturated ketones with nitro olefins

F. Tanaka, C. Barbas, Rajeswari Thayumanavan, 2002 .

A proline-catalyzed asymmetric Robinson annulation reaction

C. Barbas, T. Bui, 2000 .

Direct asymmetric anti-Mannich-type reactions catalyzed by a designed amino acid.

K N Houk, F. Tanaka, C. Barbas, 2006, Journal of the American Chemical Society.

N-Tosylimidates in highly enantioselective organocatalytic Michael reactions

C. Barbas, A. Massa, N. Utsumi, 2009 .

Synthesis of beta-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions.

F. Tanaka, C. Barbas, N. Mase, 2004, Angewandte Chemie.

One-pot enantioselective syntheses of iminosugar derivatives using organocatalytic anti-michael-anti-aza-Henry reactions.

C. Barbas, H. Uehara, Ritsuo Imashiro, 2010, Organic letters.

Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-Mannich and syn-aldol reactions.

F. Tanaka, C. Barbas, S S V Ramasastry, 2007, Journal of the American Chemical Society.

Assembly of spirooxindole derivatives via organocatalytic iminium-enamine cascade reactions.

C. Barbas, K. Anderson, Klaus Albertshofer, 2012, Organic letters.

Core structure-based design of organocatalytic [3+2]-cycloaddition reactions: highly efficient and stereocontrolled syntheses of 3,3'-pyrrolidonyl spirooxindoles.

C. Barbas, Zugui Shi, B. Tan, 2012, Chemistry.

Pipecolic acid-catalyzed direct asymmetric mannich reactions.

F. Tanaka, C. Barbas, K. Houk, 2006, Organic letters.

Construction of bispirooxindoles containing three quaternary stereocentres in a cascade using a single multifunctional organocatalyst.

C. Barbas, N. Candeias, B. Tan, 2011, Nature chemistry.

Assembly of spirooxindole derivatives containing four consecutive stereocenters via organocatalytic Michael-Henry cascade reactions.

C. Barbas, B. Tan, Klaus Albertshofer, 2012, Organic letters.

Organocatalytic asymmetric assembly reactions for the syntheses of carbohydrate derivatives by intermolecular Michael-Henry reactions

C. Barbas, Gloria Hernández-Torres, H. Uehara, 2010, Proceedings of the National Academy of Sciences.

Rationally designed amide donors for organocatalytic asymmetric Michael reactions.

C. Barbas, B. Tan, Gloria Hernández-Torres, 2012, Angewandte Chemie.

Expedient synthesis of chiral 1,2- and 1,4-diamines: protecting group dependent regioselectivity in direct organocatalytic asymmetric Mannich reactions.

F. Tanaka, C. Barbas, N. Chowdari, 2006, Organic letters.

Total synthesis of LFA-1 antagonist BIRT-377 via organocatalytic asymmetric construction of a quaternary stereocenter.

C. Barbas, N. Chowdari, 2005, Organic letters.

Direct Asymmetric Organocatalytic Michael Reactions of α,α-Disubstituted Aldehydes with β-Nitrostyrenes for the Synthesis of Quaternary Carbon-Containing Products

F. Tanaka, C. Barbas, N. Mase, 2004 .

In water, on water, and by water: mimicking nature's aldolases with organocatalysis and water.

C. Barbas, N. Mase, 2010, Organic & biomolecular chemistry.

Water-compatible organocatalysts for direct asymmetric syn-aldol reactions of dihydroxyacetone and aldehydes.

C. Barbas, S. Ramasastry, N. Utsumi, 2008, Organic letters.

Organocatalytic mannich-type reactions of trifluoroethyl thioesters.

C. Barbas, S. Kitagaki, N. Utsumi, 2008, Organic letters.

Amine-catalyzed direct asymmetric Mannich-type reactions

C. Barbas, G. Zhong, W. Notz, 2001 .

One-Pot Asymmetric Synthesis of β-Cyanohydroxymethyl α-Amino Acid Derivatives: Formation of Three Contiguous Stereogenic Centers

F. Tanaka, C. Barbas, A. Córdova, 2002 .

Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: an organocatalytic approach to 3-hydroxyoxindole derivatives.

C. Barbas, N. Candeias, T. Bui, 2010, Journal of the American Chemical Society.

Aldolase Antibodies of Remarkable Scope

R. Lerner, C. Barbas, B. List, 1998 .

Towards organocatalytic polyketide synthases with diverse electrophile scope: trifluoroethyl thioesters as nucleophiles in organocatalytic Michael reactions and beyond.

C. Barbas, S. Kitagaki, N. Utsumi, 2008, Angewandte Chemie.

Facile and stabile linkages through tyrosine: bioconjugation strategies with the tyrosine-click reaction.

C. Barbas, W. Hakamata, M. Nagano, 2013, Bioconjugate chemistry.

Tyrosine bioconjugation through aqueous ene-type reactions: a click-like reaction for tyrosine.

C. Barbas, Carlos F. Barbas, Hitoshi Ban, 2010, Journal of the American Chemical Society.

Amine-catalyzed Michael reactions of an aminoaldehyde derivative to nitroolefins

F. Tanaka, C. Barbas, Rajeswari Thayumanavan, 2007 .

Catalytic Enantioselective Direct Michael Additions of Ketones to Alkylidene Malonates.

C. Barbas, J. M. Betancort, Rajeswari Thayumanavan, 2001 .

Organocatalysis in Ionic Liquids: Highly Efficient l-Proline-Catalyzed Direct Asymmetric Mannich Reactions Involving Ketone and Aldehyde Nucleophiles

C. Barbas, D. Ramachary, N. Chowdari, 2003 .

Assembly of Spirooxindole Derivatives via Organocatalytic Iminium‐Enamine Cascade Reactions.

C. Barbas, K. Anderson, Klaus Albertshofer, 2013 .

Assembly of Spirooxindole Derivatives Containing Four Consecutive Stereocenters via Organocatalytic Michael—Henry Cascade Reactions.

C. Barbas, B. Tan, Klaus Albertshofer, 2012 .

Core Structure Based Design of Organocatalytic [3 + 2]‐Cycloaddition Reactions: Highly Efficient and Stereocontrolled Syntheses of 3,3′‐Pyrrolidonyl Spirooxindoles.

C. Barbas, Zugui Shi, B. Tan, 2012 .

Highly Efficient Hydrogen-Bonding Catalysis of the Diels—Alder Reaction of 3-Vinylindoles and Methyleneindolinones Provides Carbazolespirooxindole Skeletons.

C. Barbas, B. Tan, Gloria Hernández-Torres, 2012 .

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles.

C. Barbas, N. Candeias, B. Tan, 2011 .

Expanding the scope of cinchona alkaloid-catalyzed enantioselective alpha-aminations of oxindoles: a versatile approach to optically active 3-amino-2-oxindole derivatives.

C. Barbas, M. Borregán, T. Bui, 2009, The Journal of organic chemistry.

anti-Selective asymmetric Michael reactions of aldehydes and nitroolefins catalyzed by a primary amine/thiourea.

C. Barbas, H. Uehara, 2009, Angewandte Chemie.

The Scope of the Direct Proline-Catalyzed Asymmetric Addition of Ketones to Imines

F. Tanaka, C. Barbas, G. Zhong, 2004 .

Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: application to the formal synthesis of (+)-physostigmine.

C. Barbas, S. Syed, T. Bui, 2009, Journal of the American Chemical Society.

Asymmetric construction of spirocyclopentenebenzofuranone core structures via highly selective phosphine-catalyzed [3 + 2] cycloaddition reactions.

C. Barbas, B. Tan, Klaus Albertshofer, 2013, Organic letters.

Aldol and Mannich‐Type Reactions

C. Barbas, N. Mase, 2013 .

Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol.

F. Tanaka, C. Barbas, K. Houk, 2008, Journal of the American Chemical Society.

Organocatalytic enantioselective synthesis of metabotropic glutamate receptor ligands.

C. Barbas, J. Suri, D. Steiner, 2005, Organic letters.

Direct Organocatalytic Asymmetric Aldol Reactions of α-Amino Aldehydes: Expedient Syntheses of Highly Enantiomerically Enriched anti-β-Hydroxy-α-amino Acids

C. Barbas, Rajeswari Thayumanavan, and Fujie Tanaka, 2004 .

Enantioselective Total Synthesis of Some Brevicomins Using Aldolase Antibody 38C2

R. Lerner, C. Barbas, B. List, 1998 .

Mimicking aldolases through organocatalysis: syn-selective aldol reactions with protected dihydroxyacetone.

F. Tanaka, C. Barbas, S. Ramasastry, 2007, Organic letters.

Rapid analysis of solvent effects on enamine formation by fluorescence: how might enzymes facilitate enamine chemistry with primary amines?

F. Tanaka, C. Barbas, N. Mase, 2004 .

Rapid Fluorescent Screening for Bifunctional Amine—Acid Catalysts: Efficient Syntheses of Quaternary Carbon-Containing Aldols under Organocatalysis.

F. Tanaka, C. Barbas, N. Mase, 2004 .

Enamine Catalysis: Aldol and Mannich‐Type Reactions

F. Tanaka, C. Barbas, 2007 .

Overexpression and substrate specificity studies of phosphodeoxyribomutase and thymidine phosphorylase

C. Barbas, Chi‐Huey Wong, 1991 .

Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations.

F. Tanaka, C. Barbas, N. Mase, 2004, Journal of the American Chemical Society.

Use of a recombinant bacterial fructose-1,6-diphosphate aldolase in aldol reactions: preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1,4-dideoxy-1,4-imino-D-arabinitol, and fagomine

Chi-Huey Wong, Anthony J. Sinskey, Richard L. Pederson, 1989 .

A Catalytic Enantioselective Route to Hydroxy-Substituted Quaternary Carbon Centers: Resolution of Tertiary Aldols with a Catalytic Antibody

R. Lerner, C. Barbas, B. List, 1999 .

3-Pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones.

F. Tanaka, C. Barbas, M. Mifsud, 2006, Journal of the American Chemical Society.

Organocatalysis as a safe practical method for the stereospecific dibromination of unsaturated compounds.

C. Barbas, B. Tan, Gloria Hernández-Torres, 2012, Organic letters.

Copying Nature's Mechanism for the Decarboxylation of β-Keto Acids into Catalytic Antibodies by Reactive Immunization

R. Lerner, C. Barbas, G. Zhong, 1996 .

Organocatalytic anti‐Mannich Reactions with Dihydroxyacetone and Acyclic Dihydroxyacetone Derivatives: A Facile Route to Amino Sugars

F. Tanaka, C. Barbas, S. Ramasastry, 2008 .

The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.

R. Fuller, R. Lerner, I. Wilson, 2004, Journal of molecular biology.

Core-structure-motivated design of iminium-enolate organocascade reactions: enantioselective syntheses of 5,6-dihydroindolizines.

C. Barbas, B. Tan, Xianxing Jiang, 2013, Angewandte Chemie.

Organocatalytic Asymmetric Assembly Reactions: One‐Pot Synthesis of Functionalized β‐Amino Alcohols from Aldehydes, Ketones, and Azodicarboxylates.

C. Barbas, D. Ramachary, N. Chowdari, 2003 .

Proline‐Catalyzed Direct Asymmetric Aldol Reactions.

R. Lerner, C. Barbas, B. List, 2000 .

In vivo programming of endogenous antibodies via oral administration of adaptor ligands.

R. Fuller, C. Barbas, W. Hakamata, 2017, Bioorganic & medicinal chemistry.

Antibody-catalyzed aminolysis of a chloropyrimidine derivative.

R. Lerner, F. Tanaka, C. Barbas, 2004, Chemical communications.

The First Organocatalytic Hetero-Domino Knoevenagel-Diels-Alder-Epimerization Reactions: Diastereoselective Synthesis of Highly Substituted Spiro[cyclohexane-1,2′-indan]-1′,3′,4-triones

C. Barbas, D. Ramachary, N. Chowdari, 2003 .

Identification of a Region in the Integrin β3 Subunit That Confers Ligand Binding Specificity*

Jeffrey W. Smith, C. Barbas, C. Barbas, 1997, The Journal of Biological Chemistry.

Papain catalysed peptide synthesis: control of amidase activity and the introduction of unusual amino acids

C. Barbas, Chi‐Huey Wong, 1987 .

Organocatalytic Direct Michael Reaction of Ketones and Aldehydes with β-Nitrostyrene in Brine.

F. Tanaka, C. Barbas, Kaori Watanabe, 2006 .

One-pot tripeptide syntheses from three single amino acid derivatives catalyzed by papain

C. Barbas, Chi‐Huey Wong, 1988 .

Highly enantio- and diastereoselective Mannich reactions of glycine Schiff bases with in situ generated N-Boc-imines catalyzed by a cinchona alkaloid thiourea.

C. Barbas, S. Syed, Hai-le Zhang, 2010, Organic Letters.

Antibody‐catalyzed Aldol Reactions

F. Tanaka, C. Barbas, 2008 .

Direct observation of an enamine intermediate in amine catalysis.

R. Lerner, I. Wilson, F. Tanaka, 2009, Journal of the American Chemical Society.

Simultaneous, Phenotypic Knockout of VEGF-R2 and Tie-2 with an Intradiabody Enhances Antiangiogenic Effects In Vivo

C. Barbas, C. Barbas, G. Gaedicke, 2006, Klinische Padiatrie.

Reactive immunization: a unique approach to catalytic antibodies.

F. Tanaka, C. Barbas, 2002, Journal of immunological methods.

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.

R. Lerner, I. Wilson, C. Barbas, 1997, Science.

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins.

D J Segal, C. Barbas, C. Barbas, 2001, Current opinion in biotechnology.

RNA cleavage by a DNA enzyme with extended chemical functionality.

G. F. Joyce, C. Barbas, S. Santoro, 2000, Journal of the American Chemical Society.

Molecular Computation of Solutions to Combinatorial Problems

C. Barbas, J. P. Moore, Davy Ho, 2008 .

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

C. Barbas, B. Tan, Y. Ishihara, 2014 .

Construction of bispirooxindoles containing three quaternary stereocentres in a cascade using a single multifunctional organocatalyst.

C. Barbas, N. Candeias, B. Tan, 2011, Nature chemistry.

Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task.

A Heine, B List, R. Fuller, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Formylbenzene diazonium hexafluorophosphate reagent for tyrosine-selective modification of proteins and the introduction of a bioorthogonal aldehyde.

C. Barbas, W. Hakamata, M. Nagano, 2012, Bioconjugate chemistry.

Immune Versus Natural Selection : Antibody Aldolases with Enzymic Rates But Broader Scope

A Heine, B List, C. Barbas, 2022 .

Direct Asymmetric α‐Fluorination of Aldehydes.

C. Barbas, N. Mase, D. Steiner, 2005 .

Broadening the Aldolase Catalytic Antibody Repertoire by Combining Reactive Immunization and Transition State Theory: New Enantio- and Diastereoselectivities.

R. Lerner, C. Barbas, Zhong, 1999, Angewandte Chemie.

The antibody catalysis route to the total synthesis of epothilones.

C. Barbas, R. Lerner, C. Barbas, 1998, Proceedings of the National Academy of Sciences of the United States of America.