D. Hilvert

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De Novo Computational Design of Retro-Aldol Enzymes

Eric A. Althoff, Jasmine L. Gallaher, D. Baker, 2008, Science.

Critical analysis of antibody catalysis.

D. Hilvert, 2000, Annual review of biochemistry.

Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle.

H. Hellinga, D. Hilvert, K. Houk, 2008, Journal of the American Chemical Society.

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

Jasmine L. Gallaher, D. Baker, J. Siegel, 2010, Science.

Protein design by directed evolution.

D. Hilvert, P. Kast, Christian Jäckel, 2008, Annual review of biophysics.

Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.

Liang Tong, Gaetano T Montelione, Donald Hilvert, 2012, Journal of the American Chemical Society.

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes.

Albert J R Heck, Donald Hilvert, Maria Reinhardt-Szyba, 2017, The Analyst.

Virus-Inspired Function in Engineered Protein Cages.

D. Hilvert, T. Edwardson, 2019, Journal of the American Chemical Society.

De novo chemoenzymatic synthesis of sialic acid.

D. Hilvert, P. Seeberger, Pierre Stallforth, 2012, Chemical communications.

Direct NMR observation and DFT calculations of a hydrogen bond at the active site of a 44 kDa enzyme

Tim N. Heinz, D. Hilvert, A. Eletsky, 2002, Journal of biomolecular NMR.

Design, selection, and characterization of a split chorismate mutase

D. Hilvert, P. Kast, Manuel M Müller, 2010, Protein science : a publication of the Protein Society.

Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart.

I. Wilson, D. Hilvert, E. Stura, 1994, Science.

ELECTROSTATIC CATALYSIS OF THE CLAISEN REARRANGEMENT : PROBING THE ROLE OFGLU78 IN BACILLUS SUBTILIS CHORISMATE MUTASE BY GENETIC SELECTION

D. Hilvert, P. Kast, J. Hartgerink, 1996 .

Exploring the active site of chorismate mutase by combinatorial mutagenesis and selection: the importance of electrostatic catalysis.

D. Hilvert, P. Kast, M. Asif-Ullah, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Redesigning enzyme topology by directed evolution.

D. Hilvert, P. Kast, G. MacBeath, 1998, Science.

A small, thermostable, and monofunctional chorismate mutase from the archaeon Methanococcus jannaschii.

D. Hilvert, P. Kast, G. MacBeath, 1998, Biochemistry.

Chemoenzymatic Synthesis of Isotopically Labeled Chorismic Acids.

D. Hilvert, Darin J. Gustin, 1999, The Journal of organic chemistry.

Probing the role of the C-terminus of Bacillus subtilis chorismate mutase by a novel random protein-termination strategy.

D. Hilvert, P. Kast, M. Gamper, 2000, Biochemistry.

Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

D. Baker, D. Hilvert, P. Mittl, 2016, Nature Chemistry.

Mechanistic Insights into the Isochorismate Pyruvate Lyase Activity of the Catalytically Promiscuous PchB from Combinatorial Mutagenesis and Selection*

D. Hilvert, P. Kast, S. Sasso, 2005, Journal of Biological Chemistry.

Investigating and Engineering Enzymes by Genetic Selection.

Donald Hilvert, Sean V. Taylor, Peter Kast, 2001, Angewandte Chemie.

Iterative approach to computational enzyme design

Roberto A. Chica, Donald Hilvert, Stephen L. Mayo, 2012, Proceedings of the National Academy of Sciences.

Precision is essential for efficient catalysis in an evolved Kemp eliminase

Donald Hilvert, Stephen L. Mayo, Peer R. E. Mittl, 2013, Nature.

Evolution of a designed retro-aldolase leads to complete active site remodeling

David Baker, Donald Hilvert, Peter Kast, 2013, Nature chemical biology.

Biocatalysts by evolution.

Donald Hilvert, Christian Jäckel, D. Hilvert, 2010, Current opinion in biotechnology.

Surface-Engineered Cationic Nanocrystals Stable in Biological Buffers and High Ionic Strength Solutions

D. Hilvert, M. Kovalenko, M. Bodnarchuk, 2017, Chemistry of materials : a publication of the American Chemical Society.

Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.

David Baker, Liang Tong, Donald Hilvert, 2014, Journal of molecular biology.

Cell Penetration, Herbicidal Activity, and in-vivo-Toxicity of Oligo-Arginine Derivatives and of Novel Guanidinium-Rich Compounds Derived from the Biopolymer Cyanophycin.

D. Hilvert, M. Ebert, D. Seebach, 2018, Helvetica chimica acta.

Syntheses of Cyanophycin Segments for Investigations of Cell-Penetration

D. Hilvert, D. Seebach, A. Beck, 2018, Synthesis.

Molecular dynamics simulations highlight mobile regions in proteins: A novel suggestion for converting a murine V(H) domain into a more tractable species.

W F van Gunsteren, D. Hilvert, W. V. van Gunsteren, 2000, Journal of molecular biology.

Structure and dynamics of a molten globular enzyme

Donald Hilvert, Konstantin Pervushin, Beat Vögeli, 2007, Nature Structural &Molecular Biology.

Irreversible Cysteine-Selective Protein Labeling Employing Modular Electrophilic Tetrafluoroethylation Reagents.

D. Hilvert, Reinhard Zschoche, V. Matoušek, 2017, Chemistry.

Protein conformational disorder and enzyme catalysis.

D. Hilvert, Cindy Schulenburg, 2013, Topics in current chemistry.

The Chemistry of Selenocysteine

D. Hilvert, J. Beld, N. Metanis, 2011 .

Directed Evolution of a Protein Container

Donald Hilvert, D. Hilvert, K. J. Woycechowsky, 2011, Science.

Self‐Assembly of Proteinaceous Shells around Positively Charged Gold Nanomaterials Enhances Colloidal Stability in High‐Ionic‐Strength Buffers

D. Hilvert, M. Kovalenko, D. Dirin, 2020, Chembiochem : a European journal of chemical biology.

Diselenides as universal oxidative folding catalysts of diverse proteins.

D. Hilvert, K. J. Woycechowsky, J. Beld, 2010, Journal of biotechnology.

Ultrahigh-throughput screening enables efficient single-round oxidase remodelling

D. Hilvert, A. Griffiths, A. Green, 2019, Nature Catalysis.

Active site mutagenesis of the putative Diels-Alderase macrophomate synthase.

D. Hilvert, H. Oikawa, Jörg M Serafimov, 2007, Chemical communications.

Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies

D. Hilvert, M. Aebi, M. Bachmann, 2019, Nature Communications.

Laboratory evolution of virus-like nucleocapsids from nonviral protein cages

D. Hilvert, Y. Azuma, Naohiro Terasaka, 2018, Proceedings of the National Academy of Sciences.

How directed evolution reshapes energy landscapes in enzymes to boost catalysis

D. Kern, D. Hilvert, A. Cohen, 2020, Science.

Positional ordering of reacting groups contributes significantly to the efficiency of proton transfer at an antibody active site.

D. Hilvert, F. Seebeck, 2005, Journal of the American Chemical Society.

Conformational Isomerism Can Limit Antibody Catalysis*

I. Wilson, D. Hilvert, R. Müller, 2008, Journal of Biological Chemistry.

Extending the chemistry of enzymes and abzymes.

D. Hilvert, 1991, Trends in biotechnology.

Stereoselective Reactions with Catalytic Antibodies

D. Hilvert, 2007 .

Selection of Linkers for a Catalytic Single-chain Antibody Using Phage Display Technology*

D. Hilvert, N. Jiang, Y. Tang, 1996, The Journal of Biological Chemistry.

An artificial metalloenzyme for olefin metathesis.

D. Hilvert, Clemens Mayer, Dennis G. Gillingham, 2011, Chemical communications.

Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins.

D. Hilvert, D. Dinakarpandian, D. McRee, 1999, Biochemistry.

Antibody catalysis of carbon-carbon bond formation and cleavage

D. Hilvert, 1993 .

Evidence for the general base mechanism in carboxypeptidase A-catalyzed reactions: partitioning studies on nucleophiles and H2(18)O kinetic isotope effects.

D. Hilvert, G. Trainor, R. Breslow, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Toward bifunctional antibody catalysis.

D. Hilvert, K. Kikuchi, A. J. Kirby, 2006, Bioorganic & medicinal chemistry.

Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.

I. Wilson, D. Hilvert, K. Houk, 2000, Journal of molecular biology.

Thermodynamics of the Conversion of Chorismate to Prephenate: Experimental Results and Theoretical Predictions

D. Hilvert, K. Houk, P. Kast, 1997 .

Chemoenzymatic synthesis of differentially protected 3-deoxysugars

D. Hilvert, P. Seeberger, Pierre Stallforth, 2010, Nature Chemistry.

Isochorismate pyruvate lyase: a pericyclic reaction mechanism?

D. Hilvert, P. Kast, K. Baldridge, 2005, Journal of the American Chemical Society.

Isotope effects on the enzymatic and nonenzymatic reactions of chorismate.

D. Hilvert, O. Wiest, W. Cleland, 2005, Journal of the American Chemical Society.

Synthesis and application of an azobenzene amino acid as a light-switchable turn element in polypeptides

D. Hilvert, A. Aemissegger, 2007, Nature Protocols.

The road to fully programmable protein catalysis

D. Hilvert, A. Green, C. Levy, 2022, Nature.

Affinity maturation of a computationally designed binding protein affords a functional but disordered polypeptide.

D. Hilvert, P. Kast, M. Butz, 2014, Journal of structural biology.

Site‐Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract

D. Hilvert, J. Leroux, M. Gauthier, 2016, Advanced materials.

Proceedings du 23ème Conseil Solvay de Chimie "New Chemistry and New Opportunities from the Expanding Protein Universe": World Scientific Publishing

Kurt Wüthrich, Donald Hilvert, Ian A. Wilson, 2014 .

Antibody catalysis of concerted, carbon-carbon bond-forming reactions.

D. Hilvert, K. Hill, 1991, Methods in enzymology.

Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell

D. Hilvert, R. Nichols, Y. Barral, 2020, Current Biology.

Redesign of Protein Function: A Semisynthetic Selenoenzyme

D. Hilvert, Zhen Wu, 1991 .

Semisynthetic enzymes: design of flavin-dependent oxidoreductases.

D. Hilvert, E. Kaiser, Kaiser Et, 1987, Biotechnology & genetic engineering reviews.

Albumin-Catalyzed Proton Transfer

D. Hilvert, K. Kikuchi, S. Thorn, 1996 .

Functionalized cyclodextrins as holoenzyme mimics of thiamine-dependent enzymes

D. Hilvert, R. Breslow, 1984 .

Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.

D. Hilvert, G. Roelfes, 2003, Angewandte Chemie.

Facile, fmoc-compatible solid-phase synthesis of peptide C-terminal thioesters.

D. Hilvert, D. Swinnen, 2000, Organic letters.

Strategic use of non-native diselenide bridges to steer oxidative protein folding.

D. Hilvert, N. Metanis, 2012, Angewandte Chemie.

Selenoglutathione‐Mediated Rescue of Kinetically Trapped Intermediates in Oxidative Protein Folding

D. Hilvert, J. Beld, N. Metanis, 2011 .

Building proficient enzymes with foldamer prostheses.

D. Hilvert, S. Gellman, Clemens Mayer, 2014, Angewandte Chemie.

Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of α-Hydroxy Acids.

D. Hilvert, P. Mittl, Greta Markert, 2022, Journal of the American Chemical Society.

Photolyase-like repair of psoralen-crosslinked nucleic acids.

D. Hilvert, Thorsten Stafforst, 2011, Angewandte Chemie.

A photoinducible beta-hairpin.

D. Hilvert, W. V. van Gunsteren, Vincent Kräutler, 2005, Journal of the American Chemical Society.

The structure of cyanophycinase in complex with a cyanophycin degradation intermediate.

Itai Sharon, D. Hilvert, T. Schmeing, 2022, Biochimica et biophysica acta. General subjects.

Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog

I. Wilson, D. Hilvert, E. Stura, 1994, Proteins.

Crystal structure of selenosubtilisin at 2.0-A resolution.

D. Hilvert, R. Syed, J. Hogle, 1993, Biochemistry.

Experimental and computational investigation of the uncatalyzed rearrangement and elimination reactions of isochorismate.

D. Hilvert, P. Kast, K. Baldridge, 2006, Journal of the American Chemical Society.

Design and optimization of enzymatic activity in a de novo β‐barrel scaffold

D. Hilvert, P. Mittl, B. Basanta, 2022, Protein science : a publication of the Protein Society.

Structure and assembly of scalable porous protein cages

A. Heck, D. Hilvert, N. Ban, 2017, Nature Communications.

Substrate Sorting by a Supercharged Nanoreactor

D. Hilvert, Y. Azuma, D. Bader, 2017, Journal of the American Chemical Society.

Minimalist Active‐Site Redesign: Teaching Old Enzymes New Tricks

D. Hilvert, M. Toscano, K. J. Woycechowsky, 2007 .

Chemical synthesis of proteins.

D. Hilvert, 1994, Chemistry & biology.

Antibody catalysis of carbon-carbon bond formation.

D. Hilvert, 2007, Ciba Foundation symposium.

Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.

D. Hilvert, P. Kast, Alexander Kienhöfer, 2003, Journal of the American Chemical Society.

Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein

A. J. Scott, D. Hilvert, N. Ban, 2020, Science.

Evolution of dynamical networks enhances catalysis in a designer enzyme

D. Hilvert, V. Arcus, M. W. van der Kamp, 2020, bioRxiv.

Principles of Antibody Catalysis

D. Hilvert, 1996 .

Peroxide dependence of the semisynthetic enzyme selenosubtilisin.

D. Hilvert, I. M. Bell, 1993, Biochemistry.

13C isotope effect on the reaction catalyzed by prephenate dehydratase.

D. Hilvert, P. Kast, W. Cleland, 2010, Biochimica et biophysica acta.

A monofunctional and thermostable prephenate dehydratase from the archaeon Methanocaldococcus jannaschii.

D. Hilvert, P. Kast, Andreas C. Kleeb, 2006, Biochemistry.

Bottom-up Construction of a Primordial Carboxysome Mimic.

D. Hilvert, M. Rocca, Raphael Frey, 2016, Journal of the American Chemical Society.

Transition State of the Base-Promoted Ring-Opening of Isoxazoles. Theoretical Prediction of Catalytic Functionalities and Design of Haptens for Antibody Production

Donald Hilvert, Kendall N. Houk, D. Hilvert, 1996 .

Diffusion-Limited Cargo Loading of an Engineered Protein Container.

D. Hilvert, Reinhard Zschoche, 2015, Journal of the American Chemical Society.

alpha-Functionalized phosphonylphosphinates: synthesis and evaluation as transcarbamoylase inhibitors.

D. Hilvert, A. Flohr, A. Aemissegger, 1999, Journal of medicinal chemistry.

Characterization of the secreted chorismate mutase from the pathogen Mycobacterium tuberculosis

D. Hilvert, P. Kast, S. Sasso, 2005, The FEBS journal.

Conversion of a protease into an acyl transferase: selenolsubtilisin

D. Hilvert, Zhen Wu, 1989 .

Natural and synthetic selenoproteins.

D. Hilvert, N. Metanis, 2014, Current opinion in chemical biology.

Synthesis and characterization of catalytically active thiazolium gold(i)-carbenes.

D. Hilvert, Roy A. Meoded, Clément C Dince, 2017, Chemical communications.

Contribution of Oxyanion Stabilization to Kemp Eliminase Efficiency

D. Hilvert, Hajo Kries, D. Pinkas, 2020 .

Large rate accelerations in antibody catalysis by strategic use of haptenic charge

D. Hilvert, S. Thorn, R. G. Daniels, 1995, Nature.

Evolution of a highly active and enantiospecific metalloenzyme from short peptides

Bryan S. Der, B. Kuhlman, D. Hilvert, 2018, Science.

Antibody catalysis of the Diels-Alder reaction

D. Hilvert, K. Hill, M. T. Auditor, 1989 .

Selenosubtilisin as a glutathione peroxidase mimic

Donald Hilvert, D. Hilvert, Zhen Ping Wu, 1990 .

Three New Chiral Aminoethers from Tartaric Acid for Improved Asymmetric Syntheses with Organolithium Reactions. Preliminary communication

D. Hilvert, D. Seebach, G. Crass, 1979 .

Antibody-Catalyzed Concerted Chemical Reactions

D. Hilvert, 1991 .

Upregulation of an Artificial Zymogen by Proteolysis.

D. Hilvert, D. Häussinger, H. Mallin, 2016, Angewandte Chemie.

A Genetically Encodable Ligand for Transfer Hydrogenation

D. Hilvert, Clemens Mayer, 2013 .

Stereospecific Claisen rearrangement catalyzed by an antibody

D. Hilvert, K. D. Nared, Karen D. Nared, 1988 .

Catalysis of concerted reactions by antibodies: the Claisen rearrangement.

D. Hilvert, S. H. Carpenter, S. Carpenter, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine

I. Schlichting, D. Hilvert, B. Jaun, 2009, Proceedings of the National Academy of Sciences.

Selenoglutaredoxin as a Glutathione Peroxidase Mimic

D. Hilvert, G. Roelfes, Giulio Casi, 2008, Chembiochem : a European journal of chemical biology.

Kinetic studies on the peroxidase activity of selenosubtilisin.

D. Hilvert, I. M. Bell, Z. Wu, 1993, Biochemistry.

Selenocysteine-mediated backbone cyclization of unprotected peptides followed by alkylation, oxidative elimination or reduction of the selenol.

D. Hilvert, R. Quaderer, 2002, Chemical communications.

Selenoglutathione: efficient oxidative protein folding by a diselenide.

D. Hilvert, K. J. Woycechowsky, J. Beld, 2007, Biochemistry.

Small-molecule diselenides catalyze oxidative protein folding in vivo.

D. Hilvert, K. J. Woycechowsky, J. Beld, 2010, ACS chemical biology.

Catalysis of oxidative protein folding by small-molecule diselenides.

D. Hilvert, K. J. Woycechowsky, J. Beld, 2008, Biochemistry.

Preparation of the β3‐Homoselenocysteine Derivatives Fmoc‐β3hSec(PMB)‐OH and Boc‐β3hSec(PMB)‐OH for Solution and Solid‐Phase‐Peptide Synthesis and Selenoligation

D. Hilvert, D. Seebach, Giulio Casi, 2007 .

Convergent protein synthesis.

D. Hilvert, Giulio Casi, 2003, Current opinion in structural biology.

Fmoc-Compatible Solid-Phase Peptide Synthesis of Long C-Terminal Peptide Thioesters The authors are grateful to the ETH-Zürich and Novartis Pharma AG for support of this work. Fmoc=9-fluorenylmethoxycarbonyl.

D. Hilvert, Axel Sewing, 2001, Angewandte Chemie.

Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis

D. Hilvert, P. Kast, U. Krengel, 2014, Proceedings of the National Academy of Sciences.

A rationally designed aldolase foldamer.

Matthew A. Windsor, D. Hilvert, S. Gellman, 2009, Angewandte Chemie.

Harnessing selenocysteine reactivity for oxidative protein folding† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02379j Click here for additional data file.

D. Hilvert, N. Metanis, 2014, Chemical science.

Improved synthesis of C-terminal peptide thioesters on "safety-catch" resins using LiBr/THF.

D. Hilvert, R. Quaderer, 2001, Organic Letters.

5.17 – Catalysis by Antibodies

D. Hilvert, 1999 .

A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates.

Donald Hilvert, Xavier Garrabou, D. Hilvert, 2015, Angewandte Chemie.

Chiral recognition in amyloid fiber growth

D. Hilvert, G. Jeschke, P. Hellwig, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Protein Cages: From Fundamentals to Advanced Applications.

D. Hilvert, T. Edwardson, A. Steinauer, 2022, Chemical reviews.

An Active Enzyme Constructed from a 9-Amino Acid Alphabet*

Donald Hilvert, D. Hilvert, Katherina Vamvaca, 2005, Journal of Biological Chemistry.

Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold

D. Hilvert, K. Houk, R. Helgeson, 2021, Nature Chemistry.

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

David Baker, Clemens Mayer, Donald Hilvert, 2014, Proceedings of the National Academy of Sciences.

Synthesis of3-Peptides and Mixeda/3-Peptides by Thioligation

D. Hilvert, D. Seebach, T. Kimmerlin, 2002 .

Trapping Transient Protein Species by Genetic Code Expansion

D. Hilvert, M. Tinzl, 2020, Chembiochem : a European journal of chemical biology.

The putative Diels-Alderase macrophomate synthase is an efficient aldolase.

D. Hilvert, S. Kuster, Dennis G. Gillingham, 2008, Journal of the American Chemical Society.

An Antibody-Catalyzed Selenoxide Elimination

D. Hilvert, Ning Jiang, Z. Zhou, 1997 .

Studies on zinc enzymes and models

D. Hilvert, R. Breslow, J. Chin, 1983 .

New semisynthetic flavoenzymes based on a tetrameric protein template, glyceraldehyde-3-phosphate dehydrogenase

D. Hilvert, E. Kaiser, 1985 .

Non-uniform HYSCORE: Measurement, processing and analysis with Hyscorean.

Donald Hilvert, Gunnar Jeschke, Matthias Tinzl, 2019, Journal of magnetic resonance.

Two-tier supramolecular encapsulation of small molecules in a protein cage

D. Hilvert, T. Edwardson, S. Tetter, 2020, Nature Communications.

Fast Knoevenagel Condensations Catalyzed by an Artificial Schiff-Base-Forming Enzyme.

Donald Hilvert, Xavier Garrabou, D. Hilvert, 2016, Journal of the American Chemical Society.

Protein Nanocontainers from Nonviral Origin: Testing the Mechanics of Artificial and Natural Protein Cages by AFM.

D. Baker, W. Roos, G. Wuite, 2016, The journal of physical chemistry. B.

Engineered artificial carboligases facilitate regioselective preparation of enantioenriched aldol adducts.

D. Hilvert, Xavier Garrabou, Takahiro Mori, 2020, Journal of the American Chemical Society.

New Biocatalysts via Chemical Modification

D. Hilvert, I. M. Bell, 2007 .

Minimalist active-site redesign: teaching old enzymes new tricks.

Donald Hilvert, D. Hilvert, M. Toscano, 2007, Angewandte Chemie.

Capture and characterization of a reactive haem–carbenoid complex in an artificial metalloenzyme

D. Hilvert, U. Krengel, M. Reiher, 2018, Nature Catalysis.

Optimization of Enzyme Mechanism along the Evolutionary Trajectory of a Computationally Designed (Retro-)Aldolase.

D. Hilvert, Reinhard Zschoche, C. Zeymer, 2017, Journal of the American Chemical Society.

Modulating PNA/DNA hybridization by light.

D. Hilvert, Thorsten Stafforst, 2010, Angewandte Chemie.

An Antibody-Catalyzed Allylic Sulfoxide-Sulfenate Rearrangement.

D. Hilvert, A. Flohr, Z. Zhou, 1999, The Journal of organic chemistry.

A novel genetic selection system for PLP-dependent threonine aldolases

P. Marlière, D. Hilvert, M. Toscano, 2012 .

An antibody that reconstitutes the "base-on" form of B(12) coenzymes.

D. Hilvert, B. Kräutler, R. Konrat, 2002, Angewandte Chemie.

A subdomain swap strategy for reengineering nonribosomal peptides.

D. Hilvert, Hajo Kries, David L. Niquille, 2015, Chemistry & biology.

Metabolic engineering of a genetic selection system with tunable stringency

D. Hilvert, P. Kast, Lars Giger, 2007, Proceedings of the National Academy of Sciences.

Enantiocomplementary Synthesis of γ-Nitroketones Using Designed and Evolved Carboligases.

Donald Hilvert, Xavier Garrabou, D. Hilvert, 2017, Journal of the American Chemical Society.

Directed Evolution of Protein Catalysts.

Cathleen Zeymer, Donald Hilvert, D. Hilvert, 2018, Annual review of biochemistry.

Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis.

D. Hilvert, S. Gellman, L. Lavis, 2016, Organic letters.

3D structural information as a guide to protein engineering using genetic selection.

D. Hilvert, P. Kast, P Kast, 1997, Current opinion in structural biology.

Enzyme Encapsulation by a Ferritin Cage.

D. Hilvert, S. Tetter, 2017, Angewandte Chemie.

Reinvestigation of a Selenopeptide with Purportedly High Glutathione Peroxidase Activity*

D. Hilvert, Giulio Casi, 2007, Journal of Biological Chemistry.

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

D. Hilvert, Kunio Matsumoto, H. Suga, 2021, iScience.

A computational method for design of connected catalytic networks in proteins

Brian D. Weitzner, D. Baker, D. Hilvert, 2019, Protein science : a publication of the Protein Society.

De novo enzymes by computational design.

Donald Hilvert, Hajo Kries, D. Hilvert, 2013, Current opinion in chemical biology.

Cell-Specific Delivery Using an Engineered Protein Nanocage.

D. Hilvert, P. Johansen, Y. Waeckerle‐Men, 2021, ACS chemical biology.

Tailoring lumazine synthase assemblies for bionanotechnology.

D. Hilvert, T. Edwardson, Y. Azuma, 2018, Chemical Society reviews.

Modular Protein Cages for Size-Selective RNA Packaging in Vivo.

D. Hilvert, T. Edwardson, Y. Azuma, 2018, Journal of the American Chemical Society.

Diversification of Protein Cage Structure Using Circularly Permuted Subunits.

D. Hilvert, M. Herger, Y. Azuma, 2018, Journal of the American Chemical Society.

Enzyme-mediated polymerization inside engineered protein cages.

D. Hilvert, Raphael Frey, Takahiro Hayashi, 2016, Chemical communications.

Construction of Matryoshka-type structures from supercharged protein nanocages.

D. Hilvert, Matthias Künzle, T. Beck, 2015, Angewandte Chemie.

Comparative Laboratory Evolution of Ordered and Disordered Enzymes*♦

D. Hilvert, Cindy Schulenburg, Yvonne Stark, 2015, The Journal of Biological Chemistry.

Both the cis-trans equilibrium and isomerization dynamics of a single proline amide modulate β2-microglobulin amyloid assembly

Donald Hilvert, D. Hilvert, Vladimir Yu Torbeev, 2013, Proceedings of the National Academy of Sciences.

Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion

D. Baker, M. J. Bick, D. Hilvert, 2020, Proceedings of the National Academy of Sciences.

Novel enzymes through design and evolution.

D. Hilvert, K. J. Woycechowsky, Katherina Vamvaca, 2007, Advances in enzymology and related areas of molecular biology.

An evolution-based model for designing chorismate mutase enzymes

Simona Cocco, Rama Ranganathan, Martin Weigt, 2020, Science.

Directed Evolution of a Model Primordial Enzyme Provides Insights into the Development of the Genetic Code

Donald Hilvert, Jane R. Allison, Philippe Marlière, 2013, PLoS genetics.

A Noncanonical Proximal Heme Ligand Affords an Efficient Peroxidase in a Globin Fold.

Moritz Pott, Donald Hilvert, Takahiro Hayashi, 2018, Journal of the American Chemical Society.

A Chemically Programmed Proximal Ligand Enhances the Catalytic Properties of a Heme Enzyme.

Donald Hilvert, Takahiro Hayashi, Peer R. E. Mittl, 2016, Journal of the American Chemical Society.

Speeding up enzyme discovery and engineering with ultrahigh-throughput methods.

Moritz Pott, Donald Hilvert, Hans Adrian Bunzel, 2018, Current opinion in structural biology.

Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting.

Richard Obexer, Moritz Pott, Cathleen Zeymer, 2016, Protein engineering, design & selection : PEDS.

Equipping in vivo Selection Systems with Tunable Stringency

D. Hilvert, P. Kast, M. Neuenschwander, 2011 .

Switching antibody specificity through minimal mutation.

D. Hilvert, Caroline Aldag, Andrea Piatesi, 2008, Journal of molecular biology.

Immunological Optimization of a Generic Hydrophobic Pocket for High Affinity Hapten Binding and Diels–Alder Activity

Donald Hilvert, D. Hilvert, Andrea Piatesi, 2004, Chembiochem : a European journal of chemical biology.

Optimized production of the Diels-Alderase antibody 1E9 as a chimeric Fab

D. Hilvert, Andrea Piatesi, 2002 .

Hydrolytic antibodies: variations on a theme.

D. Hilvert, G. MacBeath, 1996, Chemistry & biology.

Substitution of proline32 by α-methylproline preorganizes β2-microglobulin for oligomerization but not for aggregation into amyloids.

D. Hilvert, M. Ebert, J. Dolenc, 2015, Journal of the American Chemical Society.

Engineered Nonviral Protein Cages Modified for MR Imaging

M. Caldwell, D. Hilvert, T. Meade, 2023, ACS applied bio materials.

Investigation of ligand binding and protein dynamics in Bacillus subtilis chorismate mutase by transverse relaxation optimized spectroscopy-nuclear magnetic resonance.

D. Hilvert, A. Eletsky, K. Pervushin, 2005, Biochemistry.

Evolution of the Chemical Step in Enzyme Catalysis

D. Hilvert, A. Kohen, Cindy Schulenburg, 2021 .

Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles.

D. Hilvert, K. Houk, K. Kikuchi, 2004, Journal of the American Chemical Society.

Characterization of Proton-Transfer Catalysis by Serum Albumins

Dan S. Tawfik, D. Hilvert, F. Hollfelder, 2000 .

Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.

K N Houk, I. Wilson, D. Hilvert, 1999, Science.

In vivo catalysis of a metabolically essential reaction by an antibody.

D. Hilvert, J. Hicks, Y. Tang, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Catalytic Antibody Technology

D. Hilvert, 2008 .

Catalytic Antibodies: Perspectives and Prospects

D. Hilvert, 1990 .

On the relationship between folding and chemical landscapes in enzyme catalysis

Arieh Warshel, Donald Hilvert, Maite Roca, 2008, Proceedings of the National Academy of Sciences.

Engineering Enzymes and Antibodies

D. Hilvert, 1992 .

Genetic selection strategies for generating and characterizing catalysts

D. Hilvert, P. Kast, 1996 .

Shape Complementarity, Binding‐Site Dynamics, and Transition State Stabilization: A Theoretical Study of Diels–Alder Catalysis by Antibody 1E9

D. Hilvert, K. Houk, Q. Deng, 2000, Chembiochem : a European journal of chemical biology.

Genetic selection as a tool in mechanistic enzymology and protein design.

D. Hilvert, 2000, Ernst Schering Research Foundation workshop.

I. Wilson, M. Taussig, D. Hilvert, 1996 .

Emergence of a negative activation heat capacity during evolution of a designed enzyme.

D. Hilvert, P. Mittl, A. Mulholland, 2019, Journal of the American Chemical Society.

Enhancing promiscuous chemistries of a Schiff-base forming enzyme by divergent evolution.

Duncan S Macdonald, Donald Hilvert, D. Hilvert, 2020, Methods in enzymology.

Kinetic consequences of introducing a proximal selenocysteine ligand into cytochrome P450cam.

D. Hilvert, M. Reiher, An Vandemeulebroucke, 2015, Biochemistry.

AN EFFICIENT PREPARATION OF TETRAMETHYLALLENE

D. Hilvert, T. Morton, M. Jacobs, 1981 .

Reprogramming nonribosomal peptide synthetases for "clickable" amino acids.

Benedikt M Wanner, D. Hilvert, Hajo Kries, 2014, Angewandte Chemie.

Deciphering enzymes. Genetic selection as a probe of structure and mechanism.

D. Hilvert, K. J. Woycechowsky, 2004, European journal of biochemistry.

Genetic selection as a probe of structure and mechanism

D. Hilvert, K. J. Woycechowsky, 2004 .

Structure and function of a hexameric cyanophycin synthetase 2

Itai Sharon, D. Hilvert, T. Schmeing, 2023, bioRxiv.

A cryptic third active site in cyanophycin synthetase creates primers for polymerization

Itai Sharon, D. Hilvert, N. Moitessier, 2022, Nature Communications.

Structures and function of the amino acid polymerase cyanophycin synthetase

Itai Sharon, D. Hilvert, D. Seebach, 2021, Nature Chemical Biology.

Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2.

Itai Sharon, D. Hilvert, T. Schmeing, 2022, ACS chemical biology.

A simple tagging system for protein encapsulation.

D. Hilvert, W. Zhuang, K. J. Woycechowsky, 2006, Journal of the American Chemical Society.

The C-terminal peptide of Aquifex aeolicus riboflavin synthase directs encapsulation of native and foreign guests by a cage-forming lumazine synthase

D. Hilvert, Reinhard Zschoche, Y. Azuma, 2017, The Journal of Biological Chemistry.

Tunnel plasticity and quaternary structural integrity of a pentameric protein ring

D. Hilvert, F. Seebeck, Kenneth J. Woycechowsky, 2006, Protein science : a publication of the Protein Society.

Self-Assembly of Proteinaceous Multishell Structures Mediated by a Supercharged Protein.

D. Hilvert, E. Sasaki, 2016, The journal of physical chemistry. B.

Enzyme Encapsulation in an Engineered Lumazine Synthase Protein Cage.

D. Hilvert, Y. Azuma, 2018, Methods in molecular biology.

Consensus protein design without phylogenetic bias.

Frances H Arnold, Donald Hilvert, Christian Jäckel, 2010, Journal of molecular biology.

Kinetics and thermodynamics of ligand binding to a molten globular enzyme and its native counterpart.

D. Hilvert, I. Jelesarov, Katherina Vamvaca, 2008, Journal of molecular biology.

Is chorismate mutase a prototypic entropy trap? - Activation parameters for the Bacillus subtilis enzyme

Donald Hilvert, Peter Kast, D. Hilvert, 1996 .

1H NMR spectroscopic studies of selenosubtilisin.

K. L. House, D. Hilvert, R. B. Dunlap, 1993, Biochemistry.

Synthesis of beta-hydroxy-alpha-amino acids with a reengineered alanine racemase.

D. Hilvert, Lars Giger, Kateryna Fesko, 2008, Bioorganic & medicinal chemistry letters.

Site-directed mutagenesis shows that tyrosine 248 of carboxypeptidase A does not play a crucial role in catalysis

W. Rutter, C. Craik, D. Hilvert, 1985, Nature.

Efficientin VivoSynthesis and Rapid Purification of Chorismic Acid Using an EngineeredEscherichia coliStrain

Donald Hilvert, Peter Kast, D. Hilvert, 1997 .

Nonribosomal biosynthesis of backbone-modified peptides.

D. Hilvert, Hajo Kries, Takahiro Mori, 2018, Nature chemistry.

Engineered Metalloenzymes with Non-Canonical Coordination Environments.

D. Hilvert, A. Green, Takahiro Hayashi, 2018, Chemistry.

Stereodivergent Evolution of Artificial Enzymes for the Michael Reaction.

Donald Hilvert, Xavier Garrabou, D. Hilvert, 2018, Angewandte Chemie.

Design of protein catalysts.

Donald Hilvert, D. Hilvert, 2013, Annual review of biochemistry.

Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design.

David Baker, Donald Hilvert, Eric A. Althoff, 2011, Journal of molecular biology.

Robust design and optimization of retroaldol enzymes

Daniel Herschlag, Donald Hilvert, Eric A. Althoff, 2012, Protein science : a publication of the Protein Society.

An enzymatic molten globule: efficient coupling of folding and catalysis.

Donald Hilvert, Konstantin Pervushin, Peter Kast, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Rational Engineering of a Designed Protein Cage for siRNA Delivery.

D. Hilvert, T. Edwardson, Takahiro Mori, 2018, Journal of the American Chemical Society.

Teaching old enzymes new tricks

D. Hilvert, 2010 .

A simple selection strategy for evolving highly efficient enzymes

Donald Hilvert, Peter Kast, Martin Neuenschwander, 2007, Nature Biotechnology.

Nonessential active site residues modulate selenosubtilisin's kinetic mechanism.

D. Hilvert, E. Peterson, 1995, Biochemistry.

Structural characterization of selenosubtilisin by selenium-77 NMR spectroscopy

K. L. House, D. Hilvert, R. B. Dunlap, 1992 .

Structural characterization of selenosubtilisin by sup 77 Se-NMR spectroscopy

K. L. House, D. Hilvert, R. B. Dunlap, 1991 .

Evidence against a crucial role for the phenolic hydroxyl of Tyr-248 in peptide and ester hydrolyses catalyzed by carboxypeptidase A: comparative studies of the pH dependencies of the native and Phe-248-mutant forms

W. Rutter, D. Hilvert, E. Kaiser, 1986 .

Bacillus subtilis chorismate mutase is partially diffusion-controlled.

D. Hilvert, P. Kast, P. Mattei, 1999, European journal of biochemistry.

Heavy Atom Isotope Effects Reveal a Highly Polarized Transition State for Chorismate Mutase

D. Hilvert, P. Kast, O. Wiest, 1999 .

cis-trans Peptide-Bond Isomerization in alpha-Methylproline Derivatives

D. Hilvert, M. Ebert, W. Schweizer, 2012 .

Monitoring Catalytic Activity by Immunoassay: Implications for Screening

D. Hilvert, G. MacBeath, 1994 .

Enhancing activity and controlling stereoselectivity in a designed PLP-dependent aldolase.

D. Hilvert, M. Toscano, Manuel M Müller, 2007, Angewandte Chemie.

Stereoselectivity and expanded substrate scope of an engineered PLP-dependent aldolase.

Donald Hilvert, Kim K Baldridge, Celine Amoreira, 2006, Angewandte Chemie.

A Strategically Positioned Cation Is Crucial for Efficient Catalysis by Chorismate Mutase*

D. Hilvert, P. Kast, Songlin Li, 2000, The Journal of Biological Chemistry.

Kinetic characterization of spiropyrans in aqueous media.

D. Hilvert, Thorsten Stafforst, 2009, Chemical communications.

Evolution-based design of chorismate mutase enzymes

Simona Cocco, Donald Hilvert, Rama Ranganathan, 2020, bioRxiv.

Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme

D. Hilvert, U. Krengel, M. Reiher, 2018 .

Searching sequence space for protein catalysts

Donald Hilvert, Sean V. Taylor, Peter Kast, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Efficient in vitro encapsulation of protein cargo by an engineered protein container.

Donald Hilvert, D. Hilvert, Z. Pianowski, 2012, Journal of the American Chemical Society.

Selenosubtilisin's peroxidase activity does not require an intact oxyanion hole

D. Hilvert, E. Peterson, 1997 .

A highly active thermophilic semisynthetic flavoenzyme

D. Hilvert, E. Kaiser, Y. Hatanaka, 1988 .

High-Mass MALDI-MS Analysis for the Investigation of Protein Encapsulation within an Engineered Capsid Forming Protein

D. Hilvert, R. Zenobi, Raphael Frey, 2017 .

Structural origins of efficient proton abstraction from carbon by a catalytic antibody.

Donald Hilvert, Ian A Wilson, I. Wilson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

I. Wilson, D. Hilvert, P. Verdino, 2008, Proceedings of the National Academy of Sciences.

Chemoselective Henry Condensations Catalyzed by Artificial Carboligases.

D. Hilvert, Xavier Garrabou, D. Macdonald, 2017, Chemistry.

DNA Nanoparticles for Improved Protein Synthesis In Vitro

L. Mazutis, V. Kiseliovas, D. Hilvert, 2016, Angewandte Chemie.

An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket

I. Wilson, D. Hilvert, R. Müller, 2009, Proceedings of the National Academy of Sciences.

Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation.

D. Hilvert, F. Seebeck, 2003, Journal of the American Chemical Society.

Probing enzyme quaternary structure by combinatorial mutagenesis and selection

D. Hilvert, P. Kast, G. MacBeath, 1998, Protein science : a publication of the Protein Society.

Exploring sequence constraints on an interhelical turn using in vivo selection for catalytic activity

D. Hilvert, P. Kast, G. MacBeath, 1998, Protein science : a publication of the Protein Society.

Cyanophycin and its biosynthesis: not hot but very cool.

Itai Sharon, D. Hilvert, T. Schmeing, 2023, Natural product reports.

Quantitative Packaging of Active Enzymes into a Protein Cage.

D. Hilvert, Reinhard Zschoche, Y. Azuma, 2016, Angewandte Chemie.

Relative tolerance of mesostable and thermostable protein homologs to extensive mutation

Donald Hilvert, Peter Kast, D. Hilvert, 2006, Proteins.

An N-terminal protein degradation tag enables robust selection of highly active enzymes.

D. Hilvert, P. Kast, M. Butz, 2011, Biochemistry.

Simultaneous optimization of enzyme activity and quaternary structure by directed evolution

D. Hilvert, M. Butz, Katherina Vamvaca, 2005, Protein science : a publication of the Protein Society.

Investigating and Engineering Enzymes by Genetic Selection

Sean V. Taylor, D. Hilvert, P. Kast, 2001 .

New enzymes from combinatorial library modules.

Donald Hilvert, Peter Kast, D. Hilvert, 2004, Methods in enzymology.

Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog

I. Wilson, D. Hilvert, E. Stura, 1994 .

A photoswitchable miniprotein based on the sequence of avian pancreatic polypeptide.

P. Güntert, D. Hilvert, O. Zerbe, 2006, Angewandte Chemie.

Active Site Plasticity of a Computationally Designed Retro‐Aldolase Enzyme

David Baker, Donald Hilvert, D. Hilvert, 2014 .

Harnessing protein symmetry for enzyme design

D. Hilvert, Lisa M. Henning, Bigna Wörsdörfer, 2012 .

Harnessing selenocysteine reactivity for oxidative protein folding† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02379j Click here for additional data file.

D. Hilvert, N. Metanis, 2014, Chemical science.

Analysis of electrostatic coupling throughout the laboratory evolution of a designed retroaldolase

M. Ondrechen, D. Hilvert, M. Pott, 2021, Protein science : a publication of the Protein Society.

Tailor-made peptide synthetases.

D. Hilvert, Hajo Kries, 2011, Chemistry & biology.

Chiral recognition in amyloid fiber growth

D. Hilvert, G. Jeschke, P. Hellwig, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Diffusion-Limited Cargo Loading of an Engineered Protein Container.

D. Hilvert, Reinhard Zschoche, 2015, Journal of the American Chemical Society.

Directed Evolution of a Protein Container

D. Hilvert, K. J. Woycechowsky, Bigna Wörsdörfer, 2011, Science.

Enzyme-mediated polymerization inside engineered protein cages.

D. Hilvert, Raphael Frey, Takahiro Hayashi, 2016, Chemical communications.

Comment on: “Computer Simulations Reveal an Entirely Entropic Activation Barrier for the Chemical Step in a Designer Enzyme”

D. Hilvert, V. Arcus, M. W. van der Kamp, 2023, ACS Catalysis.

Virus-Inspired Function in Engineered Protein Cages.

D. Hilvert, T. Edwardson, 2019, Journal of the American Chemical Society.

A Chemically Programmed Proximal Ligand Enhances the Catalytic Properties of a Heme Enzyme.

D. Hilvert, P. Mittl, A. Green, 2016, Journal of the American Chemical Society.

Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle.

H. Hellinga, D. Hilvert, K. Houk, 2008, Journal of the American Chemical Society.

A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates.

D. Hilvert, Xavier Garrabou, T. Beck, 2015, Angewandte Chemie.

Medium effects in antibody-catalyzed reactions

D. Hilvert, T. Kramer, C. Lewis, 1991, Science.

Modulating PNA/DNA hybridization by light.

D. Hilvert, Thorsten Stafforst, 2010, Angewandte Chemie.

Building proficient enzymes with foldamer prostheses.

D. Hilvert, S. Gellman, Clemens Mayer, 2014, Angewandte Chemie.

Binding of a high-energy substrate conformer in antibody catalysis.

P. Wright, D. Hilvert, T. Tarasow, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Laboratory evolution of virus-like nucleocapsids from nonviral protein cages

D. Hilvert, Y. Azuma, Naohiro Terasaka, 2018, Proceedings of the National Academy of Sciences.

An artificial metalloenzyme for olefin metathesis.

D. Hilvert, Clemens Mayer, Dennis G. Gillingham, 2011, Chemical communications.

Bifunctional catalysis of proton transfer at an antibody active site.

I. Wilson, D. Hilvert, R. Müller, 2007, Journal of the American Chemical Society.

Relative tolerance of an enzymatic molten globule and its thermostable counterpart to point mutation.

D. Hilvert, K. J. Woycechowsky, A. Choutko, 2008, Biochemistry.

Complementary charge-driven encapsulation of functional protein by engineered protein cages in cellulo.

D. Hilvert, J. Heddle, V. Malolan, 2023, Journal of materials chemistry. B.

Reprogramming Nonribosomal Peptide Synthesis by Surgical Mutation

D. Hilvert, Douglas A. Hansen, David L. Niquille, 2019, Synlett.

Strategic use of non-native diselenide bridges to steer oxidative protein folding.

D. Hilvert, N. Metanis, 2012, Angewandte Chemie.

Enantiocomplementary Synthesis of γ-Nitroketones Using Designed and Evolved Carboligases.

D. Hilvert, Xavier Garrabou, Rebecca Verez, 2017, Journal of the American Chemical Society.

Probing an acyl enzyme of selenosubtilisin by raman spectroscopy

D. Hilvert, P. Carey, M. O'Connor, 1996 .

Promiscuity in Antibody Catalysis: Esterolytic Activity of the Decarboxylase 21D8

D. Hilvert, K. Hotta, A. Backes, 2003 .

Design, selection, and characterization of a split chorismate mutase

D. Hilvert, P. Kast, Manuel M Müller, 2010, Protein science : a publication of the Protein Society.

Investigation of the enzymatic and nonenzymatic cope rearrangement of carbaprephenate to carbachorismate.

D. Hilvert, B. Jaun, A. Aemissegger, 2002, The Journal of organic chemistry.