L. Chung

Improving catalytic function by ProSAR-driven enzyme evolution

John C Whitman, Steven K. Ma, S. C. Davis, 2007, Nature Biotechnology.

Elucidating the mechanism of cis double bond formation in epothilone biosynthesis.

L. Chung, R. Reid, J. Carney, 2004, Journal of the American Chemical Society.

A New Substrate Specificity for Acyl Transferase Domains of the Ascomycin Polyketide Synthase in Streptomyces hygroscopicus *

Yaoquan Liu, L. Chung, J. Carney, 2002, The Journal of Biological Chemistry.

Generation of New Epothilones by Genetic Engineering of a Polyketide Synthase in Myxococcus xanthus

L. Chung, C. Starks, J. Carney, 2005, The Journal of Antibiotics.

The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

L. Chung, K. Wu, L. Katz, 2000, Gene.

Cloning and heterologous expression of the epothilone gene cluster.

C. Khosla, L. Chung, J. Carney, 2000, Science.

Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.

L. Chung, J. Carney, L. Liu, 2001, The Journal of antibiotics.

Genetically Engineered Analogs of Ascomycin for Nerve Regeneration

L. Chung, J. Voda, B. Gold, 2002, Journal of Pharmacology and Experimental Therapeutics.