D. Acampora

A. Simeone, D. Acampora, P. Andrews, 1991, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.

M. D'Esposito, A. Simeone, D. Acampora, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms.

M Alcalay, A. Simeone, D. Acampora, 1992, Oncogene.

Reorganization of enhancer patterns in transition from naive to primed pluripotency.

A. Simeone, D. Acampora, Zhixiang Wu, 2014, Cell stem cell.

Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast.

A. Simeone, D. Acampora, Daniela Omodei, 2016, Cell reports.

Differential and stage-related expression in embryonic tissues of a new human homoeobox gene

C. Peschle, A. Simeone, D. Acampora, 1986, Nature.

Otx2 Controls Identity and Fate of Glutamatergic Progenitors of the Thalamus by Repressing GABAergic Differentiation

A. Simeone, E. Puelles, D. Acampora, 2006, The Journal of Neuroscience.

Altered dopaminergic innervation and amphetamine response in adult Otx2 conditional mutant mice

G. Fisone, W. Wurst, A. Simeone, 2006, Molecular and Cellular Neuroscience.

Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis

T. Hoang, A. Simeone, D. Acampora, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Nested expression domains of four homeobox genes in developing rostral brain

M. Gulisano, A. Simeone, D. Acampora, 1992, Nature.

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

A. Simeone, D. Acampora, P. Andrews, 1990, Nature.

Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila.

A. Simeone, D. Acampora, D. Gerlich, 1998, Development.

Identification of sixteen novel candidate genes for late onset Parkinson’s disease

Sonja W. Scholz, Miguel Ángel Martínez, D. Hernandez, 2021, Molecular Neurodegeneration.

Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability.

W. Wurst, A. Simeone, D. Acampora, 2013, Developmental biology.

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP

W. Wurst, A. Simeone, D. Acampora, 2010, Nature Neuroscience.

Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon

W. Wurst, A. Simeone, D. Acampora, 2008, Development.

Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants

A. Simeone, D. Acampora, L. Bally-Cuif, 2006, Development.

Otx2 restricts entry to the mouse germline

A. Simeone, D. Acampora, Man Zhang, 2018, Nature.

Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.

M. Gulisano, A. Simeone, D. Acampora, 1992, The EMBO journal.

Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system.

M. D'Esposito, A. Carè, A. Simeone, 1989, Differentiation; research in biological diversity.

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

B. Spencer‐Dene, D. Acampora, C. Missero, 2012, EMBO molecular medicine.

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

A. Simeone, D. Acampora, P. Comoglio, 1995, Oncogene.

The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord

Michael Brand, Hamid Meziane, Mohammed Selloum, 2013, PeerJ.

The role of Otx2 in organizing the anterior patterning in mouse.

A. Simeone, D. Acampora, 2001, The International journal of developmental biology.

Sequential activation of human HOX2 homeobox genes by retinoic acid in embryonal carcinoma cells.

A. Simeone, D. Acampora, P. Andrews, 1990 .

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

M. D'Esposito, A. Simeone, D. Acampora, 1991, Mechanisms of Development.

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system

A. Simeone, D. Acampora, C. Arra, 1995, Mechanisms of Development.

Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and drosophila

A. Simeone, D. Acampora, J. Casanova, 1994, Neuron.

Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5.

G. Merlo, A. Simeone, D. Acampora, 1999, Development.

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

A. Simeone, D. Acampora, E. Boncinelli, 1993, The EMBO journal.

Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain

W. Wurst, A. Simeone, E. Puelles, 2003, Nature Neuroscience.

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes.

A. Simeone, D. Acampora, F. Tuorto, 1999, Development.

Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH.

P. Macchia, P. Brûlet, A. Simeone, 1998, Development.

Epilepsy and brain abnormalities in mice lacking the Otx1 gene

P. Brûlet, A. Simeone, D. Acampora, 1996, Nature Genetics.

Otx genes in brain morphogenesis

M. Gulisano, A. Simeone, D. Acampora, 2001, Progress in Neurobiology.

At least three human homeoboxes on chromosome 12 belong to the same transcription unit.

M. D'Esposito, A. Simeone, D. Acampora, 1988, Nucleic acids research.

Role of Otx transcription factors in brain development

A. Simeone, E. Puelles, D. Acampora, 2003 .

Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition

A. Simeone, D. Acampora, L. D. Di Giovannantonio, 2013, Development.

Cloning and characterization of two members of the vertebrate Dlx gene family.

M. D'Esposito, M. Gulisano, A. Simeone, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila

Michael Primig, Martin Strahm, Ulrich Certa, 2002, Genome Biology.

Developmental rescue of Drosophila cephalic defects by the human Otx genes.

A. Simeone, D. Acampora, H. Reichert, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR.

A. Simeone, D. Acampora, A. Annino, 2001, Development.

Otx genes in evolution: are they involved in instructing the vertebrate brain morphology?

A. Simeone, D. Acampora, A. Annino, 2001, Journal of anatomy.

Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7.

M. D'Esposito, M. Gulisano, A. Simeone, 1991, Nucleic acids research.

EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2.

M. D'Esposito, A. Simeone, D. Acampora, 1991, Genomics.

Expression of HOX homeogenes in human neuroblastoma cell culture lines.

M. D'Esposito, A. Simeone, D. Acampora, 1990, Differentiation; research in biological diversity.

Human HOX genes are differentially activated by retinoic acid in embryonal carcinoma cells according to their position within the four loci.

M. D'Esposito, A. Simeone, D. Acampora, 1990, Cell differentiation and development : the official journal of the International Society of Developmental Biologists.

Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation.

A. Simeone, D. Acampora, F. Tuorto, 1998, Development.

The transcription factor Otx2 regulates choroid plexus development and function

Magdalena Götz, Johannes Beckers, A. Simeone, 2013, Development.

Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family

Salvatore Oliviero, A. Simeone, D. Acampora, 1998, Mechanisms of Development.

Patterning of the mammalian cochlea.

A. Simeone, D. Acampora, R. Cantos, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Human homoeobox-containing genes in development.

M. D'Esposito, A. Simeone, D. Acampora, 1987, Human reproduction.

Human cDNA clones containing homeo box sequences.

A. Simeone, D. Acampora, E. Boncinelli, 1985, Cold Spring Harbor symposia on quantitative biology.

Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma.

A. Simeone, D. Acampora, S. Casola, 2009, The American journal of pathology.

OtxGenes and the Genetic Control of Brain Morphogenesis

M. Gulisano, A. Simeone, D. Acampora, 1999, Molecular and Cellular Neuroscience.

The TINS Lecture Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis

A. Simeone, D. Acampora, Dario Acampora, 1999, Trends in Neurosciences.

Otx genes in corticogenesis and brain development.

A. Simeone, D. Acampora, P. Barone, 1999, Cerebral cortex.

The role of Otx and Otp genes in brain development.

A. Simeone, D. Acampora, M. Di Bonito, 2000, The International journal of developmental biology.

Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells

A. Simeone, D. Acampora, I. Chambers, 2017, Stem cell reports.

OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm.

A. Simeone, E. Puelles, D. Acampora, 2003, Gene expression patterns : GEP.

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

Wolfgang Wurst, Francesca Tuorto, Alessandro Usiello, 2004, Development.

Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex

Vincenzo Nigro, D. Acampora, K. Campbell, 2011, Human molecular genetics.

Identification of the Syrian hamster cardiomyopathy gene.

Y. Hayashizaki, Y. Okazaki, D. Acampora, 1997, Human molecular genetics.

Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development

S. Ryu, W. Driever, A. Simeone, 2007, Current Biology.

Genetic and molecular roles of Otx homeodomain proteins in head development.

M. Gulisano, A. Simeone, D. Acampora, 2000, Gene.

Genetic control of brain morphogenesis through Otx gene dosage requirement.

A. Simeone, D. Acampora, F. Tuorto, 1997, Development.

Otx genes in neurogenesis of mesencephalic dopaminergic neurons

A. Simeone, E. Puelles, D. Acampora, 2011, Developmental neurobiology.

The role of Otx genes in progenitor domains of ventral midbrain.

A. Simeone, E. Puelles, D. Acampora, 2009, Advances in experimental medicine and biology.

Location and Size of Dopaminergic and Serotonergic Cell Populations Are Controlled by the Position of the Midbrain–Hindbrain Organizer

Matthias Oesterheld, Wolfgang Wurst, Massimo Signore, 2003, The Journal of Neuroscience.

The Role of Otx2 in Adult Mesencephalic–Diencephalic Dopaminergic Neurons

A. Simeone, D. Acampora, C. Tomasetti, 2011, Molecular Neurobiology.

Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity

W. Wurst, A. Simeone, D. Acampora, 2014, Development.

Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes.

A. Prochiantz, A. Simeone, D. Acampora, 2014, Human molecular genetics.

Morphological organization of somatosensory cortex in Otx1−/− mice

G. Avanzini, A. Simeone, D. Acampora, 2002, Neuroscience.

Chromosome locations of human EMX and OTX genes.

A. Simeone, D. Acampora, K. Huebner, 1994, Genomics.

Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development

S. Ryu, W. Driever, A. Simeone, 2008, Current Biology.

Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage.

A. Simeone, D. Acampora, I. Chambers, 2021, Development.

Human HOX homeobox genes.

A. Simeone, D. Acampora, E. Boncinelli, 1991, Oxford surveys on eukaryotic genes.

Potentially epileptogenic dysfunction of cortical NMDA‐ and GABA‐mediated neurotransmission in Otx1–/– mice

G. Avanzini, D. Acampora, C. Frassoni, 2001, The European journal of neuroscience.

Synaptic Properties of Neocortical Neurons in Epileptic Mice Lacking the Otx1 Gene

G. Avanzini, A. Simeone, D. Acampora, 2000, Epilepsia.

Reorganization of enhancer patterns in transition from naive to primed pluripotency.

A. Simeone, D. Acampora, Zhixiang Wu, 2014, Cell stem cell.

The transcription factor Otx2 regulates choroid plexus development and function

D. Acampora, M. Irmler, Antonio Simeone, 2013 .

Retinoic acid induces stage-specific repatterning of the rostral central nervous system.

A. Simeone, D. Acampora, F. Tuorto, 1996, Developmental biology.

Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex

A. Prochiantz, A. Simeone, D. Acampora, 2014, F1000Research.

Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition

D. Acampora, Antonio Simeone, Luca G. Di Giovannantonio, 2012 .