C. Welch

发表

Process Development and Control with Recent New FBRM, PVM, and IR

George Zhou, A. Moment, James F Cuff, 2015 .

A miniature mass spectrometer for liquid chromatography applications.

Simon E. Hamilton, C. Welch, A. Holmes, 2011, Rapid communications in mass spectrometry : RCM.

Enabling Biocatalysis by High-Throughput Protein Engineering Using Droplet Microfluidics Coupled to Mass Spectrometry

C. Welch, R. Kennedy, Jeffrey C. Moore, 2018, ACS omega.

Mass Activated Droplet Sorting (MADS) Enables High Throughput Screening of Enzymatic Reactions at Nanoliter Scale.

Paul N. Devine, C. Welch, B. Mann, 2019, Angewandte Chemie.

Microscale chiral HPLC in support of pharmaceutical process research.

Christopher J Welch, C. Welch, 2009, Chirality.

Systematic approach to conformational sampling for assigning absolute configuration using vibrational circular dichroism.

James F Cuff, X. Gong, C. Welch, 2014, Journal of medicinal chemistry.

Accelerated Forced Degradation of Pharmaceuticals in Levitated Microdroplet Reactors.

C. Welch, R. Cooks, Hongjun Gao, 2018, Chemistry.

MISER chiral supercritical fluid chromatography for high throughput analysis of enantiopurity.

Mirlinda Biba, Christopher J Welch, Kerstin Zawatzky, 2016, Journal of chromatography. A.

Mobile Tool for HPLC Reaction Monitoring

Christopher J. Welch, Wes Schafer, Jason Rehm, 2007 .

Process Development of CuI/ABNO/NMI-Catalyzed Aerobic Alcohol Oxidation

Christopher J. Welch, Joel M. Hawkins, Joseph R. Martinelli, 2015 .

Experimental Limiting Oxygen Concentrations for Nine Organic Solvents at Temperatures and Pressures Relevant to Aerobic Oxidations in the Pharmaceutical Industry

Christopher J. Welch, Joel M. Hawkins, Joseph R. Martinelli, 2014, Organic process research & development.

Rapid Determination of Humulones and Isohumulones in Beers Using MISER LC-MS Analysis

C. Welch, Kerstin Zawatzky, B. Hamper, 2017 .

Design, synthesis, and biological activities of four angiotensin II receptor ligands with gamma-turn mimetics replacing amino acid residues 3-5.

C. Welch, A. Hallberg, G. Lindeberg, 1997, Journal of medicinal chemistry.

A Convenient Void Volume Marker for Several Chiral HPLC Columns

C. Welch, W. H. Pirkle, 1991 .

High Throughput Determination of Enantiopurity by Microplate Circular Dichroism.

C. Welch, E. Anslyn, C. Wolf, 2020, The Journal of organic chemistry.

Optical Chirality Sensing with a Stereodynamic Aluminum Biphenolate Probe.

Leo A. Joyce, C. Welch, E. Sherer, 2018, The Journal of organic chemistry.

Improved method for rapid evaluation of chiral stationary phase libraries.

C. Welch, D. Mathre, P. Reider, 2001, Organic letters.

Cocktail Chromatography: Enabling the Migration of HPLC to Nonlaboratory Environments

Leo A. Joyce, C. Welch, E. Regalado, 2015 .

Application of ion mobility spectrometry in analytical support of drug substance development

X. Gong, C. Welch, Rong Xiang, 2011 .

Unusual reversal of enantioselectivity in the asymmetric autocatalysis of pyrimidyl alkanol triggered by chiral aromatic alkanols and amines.

C. Welch, Kerstin Zawatzky, K. Soai, 2017, Organic & biomolecular chemistry.

Fast methods of enantiopurity determination for the Soai reaction: towards a general enantioenrichment detector?

C. Welch, P. Sajonz, Mirlinda Biba, 2007, Chirality.

Enantioseparation of benzazoles and benzanilides on polysaccharide-based chiral columns.

C. Welch, N. Sawada, Lili Zhou, 2010, Chirality.

Investigation of a new core-shell particle column for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides.

C. Welch, J. Foley, Mirlinda Biba, 2014, Journal of pharmaceutical and biomedical analysis.

Using Electron Paramagnetic Resonance Spectroscopy To Facilitate Problem Solving in Pharmaceutical Research and Development.

C. Welch, R. Williamson, M. Reibarkh, 2016, The Journal of organic chemistry.

Possible role of salsolinol quinone methide in the decrease of RCSN-3 cell survival.

C. Welch, A. Dagnino-Subiabre, J. Segura-Aguilar, 2001, Biochemical and biophysical research communications.

Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography.

Jimmy O. DaSilva, C. Welch, L. Frey, 2014, Journal of chromatography. A.

Assessment of coulometric array electrochemical detection coupled with HPLC-UV for the absolute quantitation of pharmaceuticals.

W. Schafer, X. Gong, C. Welch, 2017, The Analyst.

Modeling and predicting chiral stationary phase enantioselectivity: An efficient random forest classifier using an optimally balanced training dataset and an aggregation strategy.

Edward C Sherer, Christian Roussel, Patrick Piras, 2018, Journal of separation science.

Mining Chromatographic Enantioseparation Data Using Matched Molecular Pair Analysis

R. Sheridan, C. Welch, E. Sherer, 2016, Molecules.

Ultrafast Chiral Chromatography as the Second Dimension in Two-Dimensional Liquid Chromatography Experiments.

D. Armstrong, C. Welch, E. Regalado, 2017, Analytical chemistry.

Evolution of chiral stationary phase design in the Pirkle laboratories

C. Welch, 1994 .

Pushing the speed limit in enantioselective supercritical fluid chromatography.

C. Welch, E. Regalado, 2015, Journal of separation science.

Visualizing small differences using subtractive chromatographic analysis.

C. Welch, M. Reibarkh, L. Du, 2016, Journal of chromatography. A.

Removal of common organic solvents from aqueous waste streams via supercritical C02 extraction: a potential green approach to sustainable waste management in the pharmaceutical industry.

C. Welch, J. Leazer, W. Leonard, 2009, Environmental science & technology.

Identification of an N-hydroxyguanidine reducing activity of xanthine oxidase.

C. Welch, J. Wikberg, M. Dambrova, 1998, European journal of biochemistry.

Next-Generation TLC: A Quantitative Platform for Parallel Spotting and Imaging.

Alexander A. Boulgakov, Leo A. Joyce, Sarah R. Moor, 2020, The Journal of organic chemistry.

Estimating chromatographic enantioselectivity (α) from gradient enantioselective chromatography data.

W. Schafer, X. Gong, C. Welch, 2011, Chirality.

Microscale HPLC enables a new paradigm for commercialization of complex chiral stationary phases.

W. Schafer, X. Gong, C. Welch, 2008, Chirality.

Microscale HPLC Predicts Preparative Performance at Millionfold Scale

W. Schafer, C. Welch, P. Sajonz, 2008 .

Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers.

C. Welch, E. Regalado, J. Schariter, 2014, Journal of chromatography. A.

Solving multicomponent chiral separation challenges using a new SFC tandem column screening tool.

C. Welch, Joe Gouker, Mirlinda Biba, 2007, Chirality.

Systematic evaluation of new chiral stationary phases for supercritical fluid chromatography using a standard racemate library.

W. Schafer, X. Gong, C. Welch, 2010, Journal of chromatography. A.

Performance to burn? Re-evaluating the choice of acetonitrile as the platform solvent for analytical HPLC

W. Schafer, X. Gong, C. Welch, 2009 .

Improving sensitivity in chiral supercritical fluid chromatography for analysis of active pharmaceutical ingredients.

C. Welch, R. Helmy, Mirlinda Biba, 2007, Chirality.

Some thoughts on the coupling of dissimilar chiral columns or the mixing of chiral stationary phases for the separation of enantiomers

C. Welch, W. H. Pirkle, 1996 .

Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0.

Jimmy O. DaSilva, C. Welch, F. Antia, 2006, Journal of chromatography. A.

Use of chiral HPLC-MS for rapid evaluation of the yeast-mediated enantioselective bioreduction of a diaryl ketone.

C. Welch, Jeffrey S. Moore, J. Moore, 2001, The Journal of organic chemistry.

An Improved Chiral Stationary Phase for the Chromatographic Separation of Underivatized Naproxen Enantiomers

C. Welch, W. H. Pirkle, 1992 .

Palladium-Catalyzed Enantioselective Arylation of Aryl Sulfenate Anions: A Combined Experimental and Computational Study.

C. Welch, R. Williamson, E. Regalado, 2017, Journal of the American Chemical Society.

Estimating optimal time for fast chromatographic separations.

C. Welch, E. Regalado, 2014, Journal of separation science.

Design and synthesis of C2-symmetric N-heterocyclic carbene precursors and metal carbenoids.

C. Welch, N. Gerasimchuk, R. E. Gawley, 2011, The Journal of organic chemistry.

Online sensing of palladium in flowing streams.

C. Welch, X. Bu, Junyong Jo, 2017, Chemical communications.

Separation of achiral analytes using supercritical fluid chromatography with chiral stationary phases

C. Welch, E. Regalado, 2015 .

Effect of particle size on the speed and resolution of chiral separations using supercritical fluid chromatography.

C. Welch, E. Regalado, Mirlinda Biba, 2014, Journal of chromatography. A.

Design, synthesis and evaluation of stationary phases for improved achiral supercritical fluid chromatography separations.

C. Welch, M. Hyun, R. McClain, 2013, Journal of chromatography. A.

SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST

C. Welch, Jennifer R. Chilenski, Mirlinda Biba, 2004, Drug Metabolism and Disposition.

Species Differential Stereoselective Oxidation of a Methylsulfide Metabolite of MK-0767, a PPAR Dual Agonist

C. Welch, Jennifer R. Chilenski, B. Karanam, 2004 .

Chromatography as an Enabling Technology in Pharmaceutical Process Development: Expedited Multikilogram Preparation of a Candidate HIV Protease Inhibitor

C. Welch, F. Antia, J. Armstrong, 2004 .

Design, synthesis, and evaluation of an improved enantioselective naproxen selector

C. Welch, W. H. Pirkle, B. Lamm, 1992 .

Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS

Robert P. Sheridan, Christopher J. Welch, Zhengwei Peng, 2018, Science.

Are We Approaching a Speed Limit for the Chromatographic Separation of Enantiomers?

C. Welch, 2017, ACS central science.

Extended length heterobifunctional coupling agents for protein conjugations.

C. Welch, G. Barnes, M. Husain, 1996, Bioconjugate chemistry.

The Flavonoid Constituents of Two Polypodium Species (Calaguala) and their Effect on the Elastase Release in Human Neutrophils

C. Welch, L. Bohlin, M. Vasänge, 1997, Planta medica.

Broad-spectrum antifungal metabolites produced by the soil bacterium Serratia plymuthica A 153

C. Welch, B. Gerhardson, J. Levenfors, 2004 .

Can the analyte-triggered asymmetric autocatalytic Soai reaction serve as a universal analytical tool for measuring enantiopurity and assigning absolute configuration?

C. Welch, K. Soai, A. Makarov, 2016, Organic & biomolecular chemistry.

Resolution of enantiomers of cis- and trans-fused C60-enone [2 + 2] photoadducts

D. Schuster, C. Welch, Stephen R. Wilson, 1993 .

Microporous affinity membranes and their incorporation into microfluidic devices for monitoring of therapeutic antibodies.

C. Welch, M. Bruening, J. Linnes, 2022, Talanta.

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

Kevin Bateman, Christopher J. Welch, Simon Berritt, 2015, Science.

Greening analytical chromatography

James F Cuff, W. Schafer, C. Welch, 2010 .

Practical Aspects of Ultrahigh Performance Liquid Chromatography

C. Welch, T. K. Natishan, Hong Gao, 2013 .

Evaluation of micro ultra high pressure liquid chromatography for pharmaceutical analysis

W. Schafer, C. Welch, D. Arnold, 2013 .

Effect of extra-column volume on practical chromatographic parameters of sub-2-μm particle-packed columns in ultra-high pressure liquid chromatography.

C. Welch, N. Wu, Li Zhang, 2012, Journal of separation science.

Evaluation and Implementation of a Commercially Available Mass-Guided SFC Purification Platform in a High Throughput Purification Laboratory in Drug Discovery

C. Welch, J. Barrow, G. Hartman, 2009 .

Rapid Analytical Method Development Using Multiparallel Microfluidic High-Performance Liquid Chromatography in Support of Pharmaceutical Process Research

W. Schafer, C. Welch, P. Sajonz, 2008 .

An Assessment of Electronic Properties of Pyrimidine and Purine Nucleosides by 15N-NMR Spectroscopy

C. Welch, X.-X. Zhou, J. Chattopadhyaya, 1988 .

Multiparallel microfluidic high-performance liquid chromatography for high-throughput normal-phase chiral analysis.

W. Schafer, C. Welch, P. Sajonz, 2007, Journal of chromatography. A.

Adsorbent Screening for Metal Impurity Removal in Pharmaceutical Process Research

Jimmy O. DaSilva, C. Welch, D. Mathre, 2005 .

Effective use of preparative chiral HPLC in a preclinical drug synthesis.

C. Welch, D. Mathre, M. Huffman, 2004, Chirality.

Adsorbent Screening Using Microplate Spectroscopy for Selective Removal of Colored Impurities from Active Pharmaceutical Intermediates

C. Welch, P. Sajonz, John Y. L. Chung, 2008 .

Chromatographic resolution of closely related species: drug metabolites and analogs.

C. Welch, E. Regalado, R. Helmy, 2014, Journal of separation science.

Chromatographic resolution of closely related species in pharmaceutical chemistry: dehalogenation impurities and mixtures of halogen isomers.

Yadan W. Chen, W. Schafer, C. Welch, 2014, Analytical chemistry.

Synthesis of 2-hydroxymethyl-1-oxaquinolizidine

C. Welch, Lena Börjesson, 1992 .

Suppression of Sclerotinia sclerotiorum apothecial formation by the soil bacterium Serratia plymuthica: identification of a chlorinated macrolide as one of the causal agents

C. Welch, B. Gerhardson, J. Borowicz, 2001 .

Synthesis and Conformational Analysis of 2,9-Disubstituted 1-Oxaquinolizidines

C. Welch, I. Csoeregh, L. Boerjesson, 1995 .

Synthesis and Conformational Analysis of 2,9‐Disubstituted 1‐ Oxaquinolizidines.

C. Welch, I. Csoeregh, L. Boerjesson, 2010 .

Shortcut to Selectivity: Make Them All and Let Preparative Chromatography Sort it Out

C. Welch, D. Conlon, D. Schenk, 2010 .

The measurement of enantiopurity using phosphorus-NMR

C. Welch, 1991 .

Synthesis of enantiomerically pure D-FDOC, an anti-HIV agent.

C. Welch, R. Schinazi, D. Liotta, 2004, Bioorganic & medicinal chemistry letters.

Is it possible to estimate the enantioselectivity of a chiral catalyst from its racemic mixture?

C. Welch, H. Kagan, M. Tsukamoto, 2003, Journal of the American Chemical Society.

Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.

Jing Li, Paul N Devine, Paul N. Devine, 2003, Journal of the American Chemical Society.

New chiral crown ether stationary phase for the liquid chromatographic resolution of alpha-amino acid enantiomers.

C. Welch, M. Hyun, B. Lipshutz, 2001, Journal of chromatography. A.

Asymmetric synthesis of 1,2,3-trisubstituted cyclopentanes and cyclohexanes as key components of substance p antagonists.

C. Welch, I. Davies, P. Reider, 2002, The Journal of organic chemistry.

Enantiopure (9‐Anthryl)(2‐piperidyl)‐ and (9‐Anthryl)(2‐pyridyl)methanols – Their Use as Chiral Modifiers for Heterogeneous Hydrogenation of Keto Esters over Pt/Al2O3

C. Welch, M. Roje, Jennifer R. Chilenski, 2007 .

Some recent high-performance liquid chromatography separations of the enantiomers of pharmaceuticals and other compounds using the Whelk-O 1 chiral stationary phase

C. Welch, S. Perrin, Ted Szczerba, 1997 .

Strategic use of preparative chiral chromatography for the synthesis of a preclinical pharmaceutical candidate.

C. Welch, Ross A. Miller, Mirlinda Biba, 2007, Chirality.

An assessment of the reactivity of guanosine and some of its derivatives to electrophiles by 15N-NMR spectroscopy

C. Welch, X.-X. Zhou, J. Chattopadhyaya, 1986 .

THE PREPARATION OF CHIRAL SALICYLALDEHYDES BASED ON KAGAN'S ETHER

C. Welch, M. Harmata, M. Kahraman, 2001 .

Chiral Chromatography in Support of Pharmaceutical Process Research

Christopher J. Welch, C. Welch, 2007 .

Reactive resin facilitated preparation of an enantiopure fluorobicycloketone.

C. Welch, I. Davies, D. Hughes, 2004, Organic & biomolecular chemistry.

An efficient preparation of β‐dimethylaminovinyl sulfone and sulfoximide, and investigation of their reactivity as dipolarophiles

C. Welch, A. N. Boa, N. Pesa, 2005 .

The reaction of 9-(2',3'-dideoxy-β-D-glycero-pent-2-enofuranosyl)-adenine derivatives with arene- and alkanesulfenyl chlorides. An unusual ring opening reaction of thiiranium ions

C. Welch, H. Bazin, J. Chattopadhyaya, 1986 .

Improved chiral stationary phase for ß-blocker enantioseparations

C. Welch, S. Perrin, 1995 .

An improved method for the direct chromatographic resolution of abscisic acid enantiomers

C. Welch, 1993 .

Looking Forward in Pharmaceutical Process Chemistry

Ian W Davies, Christopher J Welch, C. Welch, 2009, Science.

Chromatographic investigation of the slowly interconverting atropisomers of hindered naphthamides

C. Welch, W. H. Pirkle, Andrew J. Zych, 1993 .

Observations of Rhodium‐Containing Reaction Intermediates using HPLC with ICP‐MS and ESI‐MS Detection

C. Welch, Q. Tu, C. Raab, 2006 .

Does an axial propeller shape on a dirhodium(III,III) core affect equatorial ligand chirality?

C. Welch, P. Zavalij, Lei Zhou, 2011 .

The determination of the absolute configuration of a chiral molecular tweezer using CD spectroscopy

C. Welch, A. Koslowski, J. Fleischhauer, 1997 .

An alternative synthesis of cyclic aza compounds

C. Welch, Lena Börjesson, 1991 .

Liquid chromatographic resolution of racemic amines, amino alcohols and related compounds on a chiral crown ether stationary phase.

C. Welch, M. Hyun, S. Han, 2002, Journal of chromatography. A.

Chromatographic and 1H NMR support for a proposed chiral recognition model

C. Welch, W. H. Pirkle, 1994 .

A chiral 1,4-oxazin-2-one: asymmetric synthesis versus resolution, structure, conformation and VCD absolute configuration

C. Welch, L. Nafie, T. B. Freedman, 2001 .

Short communication New chiral crown ether stationary phase for the liquid chromatographic resolution of a-amino acid enantiomers

C. Welch, M. Hyun, S. Han, 2001 .

Expedited Selection of NMR Chiral Solvating Agents for Determination of Enantiopurity

Christopher J. Welch, Melodie Christensen, Lu Yang, 2016, ACS central science.

Studies on the racemization of a stereolabile 5-aryl-thiazolidinedione.

C. Welch, M. Beconi, D. Mathre, 2003, Chirality.

Molecular Clefts Derived from Kagan’s Ether. Synthesis and Solid State Inclusion Complexes of a Chiral Molecular Tweezer

C. Welch, C. Barnes, M. Harmata, 1998 .

Use of simultaneous face to face and face to edge π-π interactions to facilitate chiral recognition

C. Welch, W. H. Pirkle, 1994 .

Chromatographic separation of the enantiomers of acylated amines on chiral stationary phases

C. Welch, W. H. Pirkle, 1984 .

Chromatographic separation of the enantiomers of N-acylated heterocyclic amines

C. Welch, A. Meyers, W. H. Pirkle, 1984 .

9.06 The Use of Preparative Chiral Chromatography for Accessing Enantiopurity in Pharmaceutical Discovery and Development

C. Welch, 2014 .

History and Developments in Chromatographic Column Technology and Validation to 2001

D. Armstrong, C. Welch, C. Gehrke, 2010 .

Effects of pressure and frictional heating on protein separation using monolithic columns in reversed-phase chromatography.

C. Welch, B. Mann, Heather Wang, 2017, Journal of chromatography. A.

Ultrafast chiral separations for high throughput enantiopurity analysis.

Christopher J. Welch, Daniel W. Armstrong, Alexey A. Makarov, 2017, Chemical communications.

Progress in the design of selectors for buckminsterfullerene

C. Welch, W. H. Pirkle, 1992 .

Ultrafast separation of fluorinated and desfluorinated pharmaceuticals using highly efficient and selective chiral selectors bonded to superficially porous particles.

D. Armstrong, C. Welch, E. Regalado, 2015, Journal of chromatography. A.

Hydroxypyridyl Imines: Enhancing Chromatographic Separation and Stereochemical Analysis of Chiral Amines via Circular Dichroism.

Leo A. Joyce, C. Welch, E. Regalado, 2016, The Journal of organic chemistry.

Doubly tethered tertiary amide selectors: Modified version of Doyle et al.'s naproxen chiral stationary phase

C. Welch, W. H. Pirkle, B. Lamm, 1994 .

Effect of superfluous remote polar functionality on chiral recognition

C. Welch, W. H. Pirkle, 1992 .

Toward structure-based predictive tools for the selection of chiral stationary phases for the chromatographic separation of enantiomers.

Edward C Sherer, Christian Roussel, Patrick Piras, 2016, Journal of chromatography. A.

Current challenges and future prospects in chromatographic method development for pharmaceutical research

Christopher J. Welch, Michael B. Hicks, Lin Wang, 2017 .

9.02 High-Throughput Analysis for High-Throughput Experimentation in Organic Chemistry

Christopher J. Welch, Xiaoyi Gong, Wes Schafer, 2014 .

Molecular dynamics in dilute aqueous solutions of ethyl(hydroxyethyl)cellulose and sodium dodecyl sulfate as investigated by proton NMR relaxation

C. Welch, S. Nilsson, L. Sundelöf, 1998 .

Imine-based chiroptical sensing for analysis of chiral amines: from method design to synthetic application

Christopher J. Welch, Edward C. Sherer, Leo A. Joyce, 2014 .

Chromatographic Separation of Underivatized Naproxen Enantiomers

C. Welch, W. H. Pirkle, 1991 .

Alphitol, a phenolic substance from Alphitonia zizyphoides which inhibits prostaglandin biosynthesis in vitro.

C. Welch, L. Bohlin, P. Perera, 1998, Phytochemistry.

Chromatographic separation and assignment of absolute configuration of hydroxywarfarin isomers.

Leo A. Joyce, C. Welch, E. Regalado, 2014, Chirality.

Human Class Mu Glutathione Transferases, in Particular Isoenzyme M2-2, Catalyze Detoxication of the Dopamine Metabolite Aminochrome*

C. Welch, B. Mannervik, J. Segura-Aguilar, 1997, The Journal of Biological Chemistry.

Metabolism Studies of Polycyclic Mutagens and Carcinogens Using Liquid Chromatography with Ultraviolet and Electrochemical Detection

C. Welch, K. McMurtrey, 1986 .

Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research

Jimmy O. DaSilva, C. Welch, D. Mathre, 2005 .

Selection of an optimized adsorbent for preparative chromatographic enantioseparation by microscale screening of a second-generation chiral stationary phase library.

C. Welch, M. Protopopova, G. Bhat, 1999, Journal of combinatorial chemistry.

Chromatographic resolution of closely related species: separation of warfarin and hydroxylated isomers.

W. Schafer, C. Welch, E. Regalado, 2013, Journal of chromatography. A.

Extending the range of supercritical fluid chromatography by use of water-rich modifiers.

Jinchu Liu, Christopher J Welch, Ingrid Mergelsberg, 2013, Organic & biomolecular chemistry.

Determination of enantiomeric composition of (-)-(R)-2-tert-butyltetrahydroimidazolidin-4-one by polarimetry, 1H NMR, and chiral SFC.

C. Welch, Mirlinda Biba, G. Hernández, 2005, Chirality.

Application of Heart-Cutting 2D-LC for the Determination of Peak Purity for a Chiral Pharmaceutical Compound by HPLC

James F Cuff, C. Welch, Claire Lee, 2012, Chromatographia.

Factors influencing the separation of oligonucleotides using reversed-phase/ion-exchange mixed-mode high performance liquid chromatography columns.

Mirlinda Biba, C. Welch, D. Zewge, 2013, Journal of chromatography. A.

Liquid chromatographic separation of oligonucleotides

Christopher J. Welch, Mirlinda Biba, C. Welch, 2017 .

An Alternative Synthesis of Cyclic Aza Compounds.

C. Welch, L. Boerjesson, 1991 .

THE CHEMICAL SYNTHESIS AND ANTIVIRAL PROPERTIES OF AN ACYCLOVIR-PHOSPHOLIPID CONJUGATE

C. Welch, A. Ericson, A. Larsson, 1985 .

Synthesis of an mRNA fragment of alanyl-tRNA synthetase gene in Escherichia coli using the 6-methyl-3-pyridyl group for protection of the imide functions of uridine and guanosine.

C. Welch, J. Chattopadhyaya, X. X. Zhou, 1986, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry.

The chemical synthesis and antiviral properties of an acyclovir-phospholipid conjugate.

C. Welch, B. Oberg, A. Ericson, 1985, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry.

Synthesis of C-5 and N-3 arenesulfenyl uridines: preparation and properties of a new class of uracil protecting group

C. Welch, H. Bazin, J. Chattopadhyaya, 1985 .

An Asymmetric, Catalytic (4 + 3) Cycloaddition Reaction of Cyclopentenyl Oxyallylic Cations.

C. Welch, C. Barnes, M. Harmata, 2017, Organic letters.

Fragmentation of Polyfunctional Compounds Recorded Using Automated High-Throughput Desorption Electrospray Ionization.

R. Cooks, C. Welch, M. Le, 2021, Journal of the American Society for Mass Spectrometry.

Evaluation of C18 monolithic columns for radiochemical purity measurement.

C. Welch, V. Antonucci, D. Schenk, 2016, Journal of labelled compounds & radiopharmaceuticals.

Evaluation of core-shell particle columns for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides.

Rebecca A. Arvary, C. Welch, J. Foley, 2013, Journal of pharmaceutical and biomedical analysis.

Analysis of Mexican Amber by Carbon-13 NMR Spectroscopy

C. Welch, G. Poinar, J. B. Lambert, 1989 .

Are fluorine-rich pharmaceuticals lost by partition into fluorous phases?

C. Welch, E. Regalado, Shuwen Sun, 2016, Journal of pharmaceutical and biomedical analysis.

Novel orally bioavailable gamma-secretase inhibitors with excellent in vivo activity.

C. Welch, I. Collins, Michael A. Reilly, 2009, Journal of medicinal chemistry.

Rapid Analysis of Residual Palladium in Pharmaceutical Development Using a Catalysis-Based Fluorometric Method

Christopher J. Welch, Xiaodong Bu, C. Welch, 2013 .

The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization.

V. Hornak, W. Schafer, C. Welch, 2012, Bioorganic & Medicinal Chemistry.

Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.

V. Hornak, W. Schafer, C. Welch, 2011, ACS medicinal chemistry letters.

Factors influencing the interconversion of a new class of dibenzodiazepine sulfonamide atropisomers.

W. Schafer, C. Welch, Yan Guo, 2009, Chirality.

Serendipitous discovery of a pH-dependant atropisomer bond rotation: toward a write-protectable chiral molecular switch?

C. Welch, M. Egbertson, Mirlinda Biba, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Concerning the role of face-to-edge π-π interactions in chiral recognition

C. Welch, M. Hyun, W. H. Pirkle, 1992 .

Screening Binary Systems of Chelating Agents Combined with Carbon or Silica Gel Adsorbents: The Development of a Cost-Effective Method to Remove Palladium from Pharmaceutical Intermediates and APIs

Leopold N. Green, C. Welch, Q. Tu, 2011 .

Cyclic sulfamide gamma-secretase inhibitors.

C. Welch, J. Best, D. Beher, 2005, Bioorganic & medicinal chemistry letters.

A chiral recognition model for the chromatographic resolution of N-acylated 1-aryl-1-aminoalkanes

C. Welch, M. Hyun, W. H. Pirkle, 1983 .

Capture of reactive monophosphine-ligated palladium(0) intermediates by mass spectrometry.

Edward C Sherer, Qinghao Chen, Roy Helmy, 2015, Journal of the American Chemical Society.

An unusual effect of temperature on the chromatographic behavior of buckminsterfullerene

C. Welch, W. H. Pirkle, 1991 .

High-throughput metal screening in pharmaceutical samples by ICP-MS with automated flow injection using a modified HPLC configuration.

C. Welch, Q. Tu, Tiebang Wang, 2010, Journal of pharmaceutical and biomedical analysis.

The emergence of low-cost compact mass spectrometry detectors for chromatographic analysis

Christopher J. Welch, Simon E. Hamilton, Erik L. Regalado, 2016 .

Facile kinetic profiling of chemical reactions using MISER chromatographic analysis

Shane T. Grosser, C. Welch, K. Zawatzky, 2017 .

Antenna Biphenols: Development of Extended Wavelength Chiroptical Reporters.

Edward C Sherer, Leo A. Joyce, Christian Wolf, 2016, The Journal of organic chemistry.

Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects.

C. Welch, J. Segura-Aguilar, D. Metodiewa, 1998, Biochimica et biophysica acta.

Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

C. Welch, R. Helmy, M. Al-Sayah, 2011 .

Greening Flash Chromatography

Christopher J. Welch, Philippe G. Nantermet, C. Welch, 2016 .

GC-FID method for high-throughput analysis of residual solvents in pharmaceutical drugs and intermediates

Christopher J. Welch, Xiaoyi Gong, Erik L. Regalado, 2016 .

Supercritical fluid chromatography for GMP analysis in support of pharmaceutical development and manufacturing activities.

Xiaoyi Gong, Christopher J Welch, C. Welch, 2016, Journal of pharmaceutical and biomedical analysis.

Comparison of Multiparallel Microfluidic HPLC Instruments for High Throughput Analyses in Support of Pharmaceutical Process Research

Christopher J. Welch, Mirlinda Biba, C. Welch, 2006 .

Multiparallel chiral method development screening using an 8-channel microfluidic HPLC system.

C. Welch, P. Sajonz, Mirlinda Biba, 2006, Chirality.

Identification and characterization of isomeric intermediates in a catalyst formation reaction by means of speciation analysis using HPLC-ICPMS and HPLC-ESI-MS.

C. Welch, Q. Tu, C. Raab, 2006, Analytical chemistry.

2D‐LC as an on‐line desalting tool allowing peptide identification directly from MS unfriendly HPLC methods

C. Welch, Fanyu Meng, Jiong Yang, 2017, Journal of pharmaceutical and biomedical analysis.

High throughput analysis enables high throughput experimentation in pharmaceutical process research

Christopher J. Welch, C. Welch, 2019, Reaction Chemistry & Engineering.

Chiral non-racemic C60 derivatives: A proposed sector rule for fullerene absolute configuration

Christopher J. Welch, Stephen R. Wilson, Jingrong Cao, 1996 .

Removal of Electrophilic Potential Genotoxic Impurities Using Nucleophilic Reactive Resins

C. Welch, Zhihong Ge, Claire Lee, 2010 .

Online Analysis of Flowing Streams Using Microflow HPLC

Christopher J. Welch, Xiaoyi Gong, James F Cuff, 2009 .

Evaluation of capsaicin in chili peppers and hot sauces by MISER HPLC-ESIMS

C. Welch, E. Regalado, C. Kraml, 2014 .

Search for improved fluorinated stationary phases for separation of fluorine-containing pharmaceuticals from their desfluoro analogs.

C. Welch, E. Regalado, A. Makarov, 2015, Journal of chromatography. A.

Detection of dehalogenation impurities in organohalogenated pharmaceuticals by UHPLC-DAD-HRESIMS.

Leo A. Joyce, C. Welch, E. Regalado, 2014, Journal of pharmaceutical and biomedical analysis.

Comments on a report of the separation of the enantiomers of π-donor analytes on π-donor chiral stationary phases

C. Welch, Qing Yang, W. H. Pirkle, 1993 .

Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates

C. Welch, M. Bruening, J. Linnes, 2022, Analytical chemistry.

Determination of the enantiomeric excess of an M3 antagonist drug substance by chemometric analysis of the IR spectra of different guest-host complexes.

C. Welch, Zhihong Ge, Lili Zhou, 2006, Chirality.

Using chromatogram averaging to improve quantitation of minor impurities.

Mingxiang Lin, Oliver Trapp, Wes Schafer, 2016, Journal of chromatography. A.

Crawling out of the chiral pool: the evolution of pirkle-type chiral stationary phases

C. Welch, 1995 .

Imprintable brush-type chiral stationary phase

C. Welch, 1995 .

Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry.

C. Welch, M. G. Campbell, E. Regalado, 2014, Organic & biomolecular chemistry.

Precompetitive Collaboration on Enabling Technologies for the Pharmaceutical Industry

Christopher J. Welch, Joel M. Hawkins, Jean W. Tom, 2014 .

The Determination of the Absolute Configuration of a Chiral Molecular Tweezer Using CD Spectroscopy.

C. Welch, A. Koslowski, J. Fleischhauer, 1998 .

A competitive and reversible deactivation approach to catalysis-based quantitative assays

C. Welch, X. Bu, Junyong Jo, 2016, Nature Communications.

MISER chromatography (multiple injections in a single experimental run): the chromatogram is the graph

Christopher J. Welch, Xiaoyi Gong, Wes Schafer, 2010 .

Sustainability Challenges for Organic Chemistry: ORGN Perspective

C. Welch, 2015 .

Characterization of the enzymatic activity for biphasic competition by guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) at alpha2-adrenoceptors. II. Description of a xanthine-dependent enzymatic activity in spleen cytosol.

P. Prusis, C. Welch, J. Wikberg, 1998, Biochemical pharmacology.

DETERMINATION OF THE ENANTIOMERIZATION BARRIER OF ARYLNAPHTHALENE LIGNANS BY CRYOGENIC SUBCRITICAL FLUID CHROMATOGRAPHY AND COMPUTER SIMULATION

C. Welch, W. König, C. Wolf, 1997 .

Overcoming "speed limits" in high throughput chromatographic analysis.

Christopher J Welch, Kerstin Zawatzky, C. Welch, 2017, Journal of chromatography. A.

MICROSCALE SYNTHESIS AND SCREENING OF COMBINATORIAL LIBRARIES OF NEW CHROMATOGRAPHIC STATIONARY PHASES

C. Welch, M. Protopopova, G. Bhat, 1999 .

Search for improved fluorinated stationary phases for separation of fluorine-containing pharmaceuticals from their desfluoro analogs.

C. Welch, E. Regalado, A. Makarov, 2015, Journal of chromatography. A.

Capture of reactive monophosphine-ligated palladium(0) intermediates by mass spectrometry.

C. Welch, E. Sherer, Qiuling Zheng, 2015, Journal of the American Chemical Society.

Evaluation of core-shell particle columns for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides.

Rebecca A. Arvary, C. Welch, J. Foley, 2013, Journal of pharmaceutical and biomedical analysis.

Microporous affinity membranes and their incorporation into microfluidic devices for monitoring of therapeutic antibodies.

C. Welch, M. Bruening, J. Linnes, 2022, Talanta.

Improved chiral SFC screening for analytical method development.

W. Schafer, C. Welch, E. Regalado, 2013, Chirality.

Investigation of the stability of Chiralpak AD chiral stationary phase under various solvent conditions and development of a method to identify stationary phase-derived polymer contamination.

C. Welch, P. Sajonz, Jacob N. Fairchild, 2007, Chirality.

Ambient Pressure Desorption Ionization Mass Spectrometry in Support of Preclinical Pharmaceutical Development

Christopher J. Welch, Wes Schafer, Roy Helmy, 2010 .

Selective Removal of a Pharmaceutical Process Impurity Using a Reactive Resin

C. Welch, H. Tung, Mirlinda Biba, 2003 .