G. Velez

发表

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

Vishnu Shankar, R. Zare, Katherine J. Wert, 2020, EBioMedicine.

Whole-Exome Sequencing of Patients with Posterior Segment Uveitis.

G. Velez, A. Bassuk, S. Tsang, 2020, American journal of ophthalmology.

Molecular Surgery: Proteomics of a Rare Genetic Disease Gives Insight into Common Causes of Blindness

G. Velez, V. Mahajan, 2020, iScience.

Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy

G. Velez, A. Bassuk, S. Tsang, 2019, Scientific Reports.

Peptidomimetics Therapeutics for Retinal Disease

G. Velez, A. Bassuk, V. Mahajan, 2021, Biomolecules.

In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth.

G. Velez, A. Bassuk, V. Mahajan, 2018, bioRxiv.

In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth.

G. Velez, A. Bassuk, V. Mahajan, 2019, Genetics research.

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

G. Velez, A. Bassuk, S. Tsang, 2019, Investigative ophthalmology & visual science.

Liquid biopsy proteomics of uveal melanoma reveals biomarkers associated with metastatic risk

Cassie A. Ludwig, G. Velez, V. Mahajan, 2021, Molecular cancer.

Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO)

G. Velez, A. Bassuk, V. Mahajan, 2017, PloS one.

Gene Therapy Restores Mfrp and Corrects Axial Eye Length

G. Velez, A. Bassuk, S. Tsang, 2017, Scientific Reports.

Calpains as mechanistic drivers and therapeutic targets for ocular disease.

G. Velez, A. Bassuk, V. Mahajan, 2022, Trends in molecular medicine.

Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity

G. Velez, Jesse D. Sengillo, A. Bassuk, 2018, Orphanet Journal of Rare Diseases.

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

Daniel A. Machlab, G. Velez, A. Bassuk, 2018, Translational vision science & technology.

CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials

Katherine J. Wert, G. Velez, A. Bassuk, 2019, Human mutation.

Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans

H. Fuchs, G. Velez, A. Bassuk, 2019, Proceedings of the National Academy of Sciences.

Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface

J. J. McAnany, Katherine J. Wert, G. Velez, 2018, Free radical biology & medicine.

Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target

G. Velez, A. Bassuk, V. Mahajan, 2020, American journal of ophthalmology case reports.

Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants

G. Velez, A. Bassuk, V. Mahajan, 2020, Cell reports.

Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target.

G. Velez, A. Bassuk, S. Tsang, 2017, American journal of ophthalmology.

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

Vishnu Shankar, R. Zare, Katherine J. Wert, 2019, bioRxiv.

Surgical management of acanthamoeba chorioretinitis

G. Velez, V. Mahajan, C. Roybal, 2022, American journal of ophthalmology case reports.

Proteomic analysis of elevated intraocular pressure with retinal detachment

G. Velez, A. Bassuk, S. Tsang, 2017, American journal of ophthalmology case reports.

Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia

G. Velez, A. Bassuk, S. Tsang, 2017, Molecular genetics & genomic medicine.

Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa

G. Velez, S. Tsang, V. Mahajan, 2019, Documenta Ophthalmologica.

Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains.

G. Velez, A. Bassuk, S. Tsang, 2016, Journal of structural biology.

Structure-based phylogeny identifies Avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.

G. Velez, A. Bassuk, V. Mahajan, 2021, The Journal of clinical investigation.

A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay

Brian Brooks, Vinit B. Mahajan, Lokesh Gakhar, 2018, Cold Spring Harbor molecular case studies.

Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses

G. Velez, A. Bassuk, S. Tsang, 2016, Investigative ophthalmology & visual science.

BESTROPHIN1 mutations cause defective chloride conductance in patient stem cell-derived RPE.

G. Velez, A. Bassuk, S. Tsang, 2016, Human molecular genetics.

Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a RhoD190N mutation

G. Velez, A. Bassuk, V. Mahajan, 2019, Cellular and Molecular Life Sciences.

Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a RhoD190N mutation

G. Velez, A. Bassuk, S. Tsang, 2019, Cellular and Molecular Life Sciences.

S0016672319000065jra 1..8

G. Velez, A. Bassuk, V. Mahajan, 2019 .

Correction: Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO)

G. Velez, A. Bassuk, V. Mahajan, 2017, PLoS ONE.

OCULAR HYPERTENSION AFTER INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT

Young H. Kwon, G. Velez, V. Mahajan, 2017, Retina.

Therapeutic drug repositioning using personalized proteomics of liquid biopsies.

G. Velez, A. Bassuk, S. Tsang, 2017, JCI insight.

Acute and chronic brain infarcts on MR imaging in a 20-year-old woman with acute posterior multifocal placoid pigment epitheliopathy.

G. Velez, M. Shapiro, A. Bugnone, 2006, AJNR. American journal of neuroradiology.

Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases

Daniel A. Machlab, G. Velez, A. Bassuk, 2018, PloS one.

SCAPER‐associated nonsyndromic autosomal recessive retinitis pigmentosa

G. Velez, S. Tsang, V. Mahajan, 2019, American journal of medical genetics. Part A.

TMPRSS2 structure-phylogeny repositions Avoralstat for SARS-CoV-2 prophylaxis in mice

G. Velez, A. Bassuk, V. Mahajan, 2021, bioRxiv.

Proteomic Analysis of Autoimmune Retinopathy Implicates Neuronal Cell Adhesion Molecule as a Potential Biomarker

G. Velez, A. Bassuk, S. Tsang, 2022, Ophthalmology science.

Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy

G. Velez, A. Bassuk, S. Tsang, 2019, Scientific Reports.

Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease.

Alexander G Bassuk, Gabriel Velez, G. Velez, 2016, JAMA ophthalmology.

Human Mutation

Katherine J. Wert, G. Velez, A. Bassuk, 2019 .

Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target.

G. Velez, A. Bassuk, S. Tsang, 2017, American journal of ophthalmology.

Liquid Biopsy Proteomics in Ophthalmology

G. Velez, A. Bassuk, V. Mahajan, 2024, Journal of proteome research.