J. Fike

发表

Normal brain response after interstitial microwave hyperthermia.

P. Stauffer, J. Fike, G. Gobbel, 1991, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

A deconvolution method for evaluating indicator-dilution curves.

J. Fike, G. Gobbel, 1994, Physics in medicine and biology.

Central nervous system tumors.

P. J. Hoopes, J. Fike, P. Gavin, 1995, Seminars in veterinary medicine and surgery.

Measurement of regional cerebral blood flow using ultrafast computed tomography. Theoretical aspects.

J. Fike, G. Gobbel, C. Cann, 1991, Stroke.

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

Klaus Pfeffer, Sean J. Morrison, Arturo Alvarez-Buylla, 2003, Nature.

Radiation-Induced Cognitive Impairments are Associated with Changes in Indicators of Hippocampal Neurogenesis

Jacob Raber, S. Vandenberg, J. Fike, 2004, Radiation research.

Pathology of delayed radiation brain damage: an experimental canine model.

J. Fike, T. Phillips, R. Davis, 1987, Radiation research.

The analgesic effect of low dose focal irradiation in a mouse model of bone cancer is associated with spinal changes in neuro-mediators of nociception

L. Jasmin, A. Beitz, J. Fike, 2006, Pain.

Microglial responses after focal radiation-induced injury are affected by alpha-difluoromethylornithine.

J. Fike, G. Gobbel, K. Lamborn, 1996, International journal of radiation oncology, biology, physics.

Cellular proliferation and infiltration following interstitial irradiation of normal dog brain is altered by an inhibitor of polyamine synthesis.

J. Fike, G. Gobbel, M. Bellinzona, 1995, International journal of radiation oncology, biology, physics.

Irradiation enhances hippocampus‐dependent cognition in mice deficient in extracellular superoxide dismutase

J. Fike, J. Raber, Ting-Ting Huang, 2011, Hippocampus.

Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine.

C. Barnes, J. Fike, A. Vazdarjanova, 2009, Brain : a journal of neurology.

Redox changes induced in hippocampal precursor cells by heavy ion irradiation

J. Fike, C. Limoli, R. Rola, 2007, Radiation and environmental biophysics.

Altered growth and radiosensitivity in neural precursor cells subjected to oxidative stress

J. Fike, C. Limoli, R. Rola, 2006, International journal of radiation biology.

Neural Precursor Cells and CNS Radiation Sensitivity

J. Fike, C. Limoli, S. Rosi, 2009 .

Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials.

W. Curran, W. Woodward, R. Bristow, 2009, International journal of radiation oncology, biology, physics.

Delayed Administration of Alpha-Difluoromethylornithine Prevents Hippocampus-Dependent Cognitive Impairment after Single and Combined Injury in Mice

J. Fike, J. Raber, Ting-Ting Huang, 2014, Radiation research.

Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy

Charles B. Wilson, M. Israel, J. Fike, 1993, Journal of Neuro-Oncology.

Radiation effects in the canine brain evaluated by quantitative computed tomography.

J. Fike, T. Phillips, C. Cann, 1982, Radiology.

Lack of EC-SOD in the Microenvironment Impacts Radiation-Induced Changes in Neurogenesis

J. Fike, C. Limoli, Ting-Ting Huang, 2007 .

DIFFERENTIATION OF NEOPLASTIC FROM NON‐NEOPLASTIC LESIONS IN DOG BRAIN USING QUANTITATIVE CT

J. Fike, C. Cann, K. Turowski, 1986 .

Physiopathology of radiation-induced neurotoxicity.

J. Fike, 2011, Revue neurologique.

CNS complications of radiotherapy and chemotherapy

J. Fike, D. Ricard, J. Delattre, 2009, The Lancet.

Apoptosis is induced in the subependyma of young adult rats by ionizing irradiation

J. Fike, G. Gobbel, M. Bellinzona, 1996, Neuroscience Letters.

Indicators of Hippocampal Neurogenesis are Altered by 56Fe-Particle Irradiation in a Dose-Dependent Manner

S. Vandenberg, J. Fike, A. Obenaus, 2004, Radiation research.

Effects of altered levels of extracellular superoxide dismutase and irradiation on hippocampal neurogenesis in female mice.

J. Fike, Ting-Ting Huang, David Leu, 2013, International journal of radiation oncology, biology, physics.

Computerized tomography of brain tumors of the rostral and middle fossas in the dog.

J. Fike, C. Cann, R. Lecouteur, 1981, American journal of veterinary research.

Relative uptake of low- and high-osmolality contrast media in CT of brain tumors.

D. Norman, J. Fike, C. Cann, 1984, AJNR. American journal of neuroradiology.

Effects of whole body 56Fe radiation on contextual freezing and Arc-positive cells in the dentate gyrus

J. Fike, J. Raber, Antiño R. Allen, 2013, Behavioural Brain Research.

Measurement of vascular permeability in spinal cord using Evans Blue spectrophotometry and correction for turbidity

Douglas K. Anderson, P. Gutin, J. Fike, 1995, Journal of Neuroscience Methods.

Contrast enhancement of brain tumors and irradiated normal brain: a comparison of Iohexol and Iothalamate

D. Norman, J. Fike, C. Cann, 2004, Neuroradiology.

Comparison of xenon-enhanced CT with ultrafast CT for measurement of regional cerebral blood flow.

J. Fike, G. Gobbel, C. Cann, 1993, AJNR. American journal of neuroradiology.

Radiation exposure prior to traumatic brain injury induces responses that differ as a function of animal age

Kirsten Eilertson, Jacob Raber, Susanna Rosi, 2013, International journal of radiation biology.

CCR2 deficiency prevents neuronal dysfunction and cognitive impairments induced by cranial irradiation.

J. Fike, S. Rosi, T. Jopson, 2013, Cancer research.

Hippocampal Neurogenesis and Neuroinflammation after Cranial Irradiation with 56Fe Particles

Andre Obenaus, Susanna Rosi, J. Fike, 2008, Radiation research.

Toxicology of a Boronated Porphyrin in Dogs

J. Fike, K. Lamborn, A. Bollen, 1999, Photochemistry and photobiology.

ANATOMY OF THE CANINE ORBITAL REGION: Multiplanar Imaging by CT

J. Fike, C. Cann, R. Lecouteur, 1984 .

Computed tomography of orbital tumors in the dog.

J. Fike, C. Cann, R. Lecouteur, 1982, Journal of the American Veterinary Medical Association.

TOMY OF THE CANINE BRAIN USING HIGH RESOLUTION OMPUTED TOMOGRAPHY

J. Fike, C. Cann, R. Lecouteur, 1981 .

Canine anatomy as assessed by computerized tomography.

J E Thompson, E. W. Bradley, J. Fike, 1980, American journal of veterinary research.

X-ray computed tomography of brain tumors in cats.

J. Fike, C. Cann, J. Thompson, 1983, Journal of the American Veterinary Medical Association.

Interstitial microwave hyperthermia in a canine brain model.

P. Stauffer, P. Gutin, J. Fike, 1986, International journal of radiation oncology, biology, physics.

Contrast medium accumulation and washout in canine brain tumors and irradiated normal brain: a CT study of kinetics.

J. Fike, C. Cann, 1984, Radiology.

Repair of sublethal radiation damage by capillaries.

J. Fike, E. Gillette, D. J. Clow, 1979, International journal of radiation oncology, biology, physics.

Molecular and Cellular Biology of Moderate-Dose (1–10 Gy) Radiation and Potential Mechanisms of Radiation Protection: Report of a Workshop at Bethesda, Maryland, December 17–18, 20011

James B. Mitchell, Rosemary S. L. Wong, C. N. Coleman, 2003, Radiation research.

Irradiation induces neural precursor-cell dysfunction

M. Monje, J. Fike, T. Palmer, 2002, Nature Medicine.

Radiation Biology and Therapy of Tumors of the Central Nervous System

J. Fike, P. Sneed, P. Tofilon, 2005 .

Responses of the SVZ to Radiation and Chemotherapy

J. Fike, A. Karkar, R. Rola, 2006 .

Roles of the mammalian subventricular zone in cell replacement after brain injury

Ryan J. Felling, J. Fike, C. Y. Brazel, 2004, Progress in Neurobiology.

Long-Term Impairment of Subependymal Repopulation Following Damage by Ionizing Irradiation

J. Fike, G. Gobbel, K. Lamborn, 1999, Experimental Neurology.

Response of Postmitotic Neurons to X-Irradiation: Implications for the Role of DNA Damage in Neuronal Apoptosis

J. Fike, G. Gobbel, P. Chan, 1998, The Journal of Neuroscience.

Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.

M. Monje, J. Fike, T. Palmer, 2003, Cancer research.

Radiation Response of Neural Precursor Cells: Linking Cellular Sensitivity to Cell Cycle Checkpoints, Apoptosis and Oxidative Stress

J. Fike, T. Palmer, C. Limoli, 2004, Radiation research.

Radiation effects on neural precursor cells in the dentate gyrus

J. Fike, R. Rola, M. Andres-Mach, 2007, Cell and Tissue Research.

Models for Evaluating Agents Intended for the Prophylaxis, Mitigation and Treatment of Radiation Injuries Report of an NCI Workshop, December 3–4, 2003

C. N. Coleman, D. Zaharevitz, J. Fike, 2004, Radiation research.

Using superoxide dismutase/catalase mimetics to manipulate the redox environment of neural precursor cells.

J. Fike, C. Limoli, R. Rola, 2006, Radiation protection dosimetry.

Apoptosis in the subependyma of young adult rats after single and fractionated doses of X-rays.

J. Fike, G. Gobbel, K. Lamborn, 1997, Cancer research.

Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation

J. Fike, Rikki S. Corniola, Ting-Ting Huang, 2012, Proceedings of the National Academy of Sciences.

Histone H2AX phosphorylation in response to changes in chromatin structure induced by altered osmolarity.

J. Fike, C. Limoli, J. Cleaver, 2008, Mutagenesis.

Neural precursor cells and central nervous system radiation sensitivity.

J. Fike, C. Limoli, S. Rosi, 2009, Seminars in radiation oncology.

The Radioresponse of the Central Nervous System: A Dynamic Process

J. Fike, P. Tofilon, 2000, Radiation research.

Toxicology of BOPP in Large Animals

J. Fike, K. Lamborn, A. Bollen, 2001 .

Plasma pharmacokinetics and tissue biodistribution of boron following administration of a boronated porphyrin in dogs.

J. Fike, J. Tibbitts, J R Fike, 2000, Journal of pharmaceutical sciences.

Toxicology and Pharmacokinetics of BOPP in a Canine Model

J. Fike, J. Tibbitts, S. Kahl, 1996 .

Computed tomographic characteristics of primary brain tumors in 50 dogs.

J. Fike, R. Lecouteur, R. Higgins, 1986, Journal of the American Veterinary Medical Association.

COMPUTED TOMOGRAPHY OF BRAIN TUMORS IN THE CAUDAL FOSSA OF THE DOG

J. Fike, C. Cann, R. Lecouteur, 1981 .

Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice

S. Vandenberg, J. Fike, J. Raber, 2004, Experimental Neurology.

Paradoxical Relationship between Mn Superoxide Dismutase Deficiency and Radiation-Induced Cognitive Defects

J. Fike, Rikki S. Corniola, Ting-Ting Huang, 2012, PloS one.

Brain nuclear magnetic resonance imaging enhanced by a paramagnetic nitroxide contrast agent: preliminary report.

M Brant-Zawadzki, D. Enzmann, J. Fike, 1983, AJR. American journal of roentgenology.

X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats

J. Fike, D. Lowenstein, E. Tada, 2000, Neuroscience.

Radiation effects on neurogenic regions in the mammalian forebrain

J. Fike, R. Rola, S. Rosi, 2007 .

Radiation response of neural precursor cells.

J. Fike, C. Limoli, R. Rola, 2007, Neurosurgery clinics of North America.

Computed tomography analysis of the canine brain: effects of hemibrain X irradiation.

J. Fike, T. Phillips, C. Cann, 1984, Radiation research.

Cerebrovascular response after interstitial irradiation.

J. Fike, G. Gobbel, T. M. Seilhan, 1992, Radiation research.

Normal brain iodine-125 radiation damage: effect of dose and irradiated volume in a canine model.

J. Fike, T. Phillips, C. Cann, 1986, Radiology.

Radiation brain damage induced by interstitial 125I sources: a canine model evaluated by quantitative computed tomography.

M. Bernstein, J. Fike, T. Phillips, 1985, Neurosurgery.

Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

J. Fike, D. Lowenstein, J. Parent, 1999, The Journal of Neuroscience.

Cerebrovascular effects of the bradykinin analog RMP-7 in normal and irradiated dog brain

J. Fike, G. Gobbel, K. Lamborn, 1998, Journal of Neuro-Oncology.

Radiation necrosis.

J. Fike, C. Cann, R. Davis, 1984, Progress in experimental tumor research.

Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation

J. Fike, P. Weinstein, Jialing Liu, 2007, The European journal of neuroscience.

Modification of radiation-induced brain injury by alpha-difluoromethylornithine.

J. Fike, G. Gobbel, K. Lamborn, 1991, Radiation research.

Radiation dose response of normal brain.

J. Fike, T. Phillips, C. Cann, 1988, International journal of radiation oncology, biology, physics.

Alterations in hippocampal neurogenesis following traumatic brain injury in mice

J. Fike, Duncan R. Morhardt, R. Rola, 2006, Experimental Neurology.

A new mouse model for temporal‐ and tissue‐specific control of extracellular superoxide dismutase

J. Fike, Ting-Ting Huang, Y. Zou, 2009, Genesis.

56Fe Irradiation Alters Spine Density and Dendritic Complexity in the Mouse Hippocampus

J. Fike, J. Raber, Antiño R. Allen, 2015, Radiation research.

Cranial Irradiation Alters Dendritic Spine Density and Morphology in the Hippocampus

J. Fike, Antiño R. Allen, S. Rosi, 2012, PloS one.

cardiomyocytes and hepatocytes

M. Álvarez-Dolado, C. Lois, J. García-Verdugo, 2003 .

Irradiation attenuates neurogenesis and exacerbates ischemia‐induced deficits

J. Fike, J. Raber, P. Weinstein, 2004, Annals of neurology.

TITLE: Effects of Low Level Radiation Exposure on Neurogenesis and Cognitive Function: Mechanisms and Prevention PRINCIPAL INVESTIGATOR:

J. Fike, 2018 .

Modification of Radiation-Induced Brain Injury by α-Difluoromethylornithine

J. Fike, G. Gobbel, K. Lamborn, 1991 .

Radiotherapy of brain tumors in dogs.

J. Fike, R. Lecouteur, J. Turrel, 1984, Journal of the American Veterinary Medical Association.

Radiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD.

J. Fike, K. Lamborn, C. Limoli, 2009, Free radical biology & medicine.

Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells

C. Cotman, J. Fike, C. Limoli, 2009, Proceedings of the National Academy of Sciences.

Redox Regulation of Stem Cell Compartments: The Convergence of Radiation-Induced Normal Tissue Damage and Oxidative Stress

J. Fike, C. Limoli, R. Globus, 2012 .

Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction.

J. Fike, C. Limoli, S. Rosi, 2011, Cancer research.

Quantitative Evaluation of the Canine Brain Using Computed Tomography

J. Fike, C. Cann, W. Berninger, 1982, Journal of computer assisted tomography.

Dual energy CT scanning for analysis of brain damage due to X-irradiation

J. Fike, C. Cann, C. Süsskind, 2006, Annals of Biomedical Engineering.

Radiation Damage to Normal Canine Brain Induced by Radiation from Interstitially-Implanted 125I Sources

J. Fike, T. Phillips, C. Cann, 1984 .

Effects of Radiation Combined Injury on Hippocampal Function are Modulated in Mice Deficient in Chemokine Receptor 2 (CCR2)

J. Fike, J. Raber, Antiño R. Allen, 2013, Radiation research.

Effects of 56Fe radiation on hippocampal function in mice deficient in chemokine receptor 2 (CCR2)

J. Fike, J. Raber, Antiño R. Allen, 2013, Behavioural Brain Research.

Trauma‐induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation

Andre Obenaus, Jacob Raber, Susanna Rosi, 2012, Hippocampus.

The Polyamine Inhibitor Alpha-Difluoromethylornithine Modulates Hippocampus-Dependent Function after Single and Combined Injuries

J. Fike, J. Raber, Antiño R. Allen, 2012, PloS one.

Neurogenesis in the epileptic brain: a brief overview from temporal lobe epilepsy

J. Fike, J. Łuszczki, M. Andres-Mach, 2011, Pharmacological reports : PR.

Lack of extracellular superoxide dismutase (EC-SOD) in the microenvironment impacts radiation-induced changes in neurogenesis.

J. Fike, C. Limoli, Ting-Ting Huang, 2007, Free radical biology & medicine.

Radiation brain injury is reduced by the polyamine inhibitor alpha-difluoromethylornithine.

J. Fike, G. Gobbel, L. Marton, 1994, Radiation research.

Measurement of regional cerebral blood flow in the dog using ultrafast computed tomography. Experimental validation.

J. Fike, G. Gobbel, C. Cann, 1991, Stroke.

Effect of behavioral testing on spine density of basal dendrites in the CA1 region of the hippocampus modulated by 56Fe irradiation

J. Fike, J. Raber, Antiño R. Allen, 2016, Behavioural Brain Research.

Effects of 56Fe-Particle Cranial Radiation on Hippocampus-Dependent Cognition Depend on the Salience of the Environmental Stimuli

Jacob Raber, Susanna Rosi, J. Fike, 2011, Radiation research.

28Silicon Radiation-Induced Enhancement of Synaptic Plasticity in the Hippocampus of Naïve and Cognitively Tested Mice

J. Fike, J. Raber, R. Vlkolinský, 2014, Radiation research.

Cranial irradiation alters the behaviorally induced immediate-early gene arc (activity-regulated cytoskeleton-associated protein).

J. Fike, S. Rosi, M. Andres-Mach, 2008, Cancer research.

High-LET Radiation Induces Inflammation and Persistent Changes in Markers of Hippocampal Neurogenesis

J. Fike, A. Obenaus, C. Limoli, 2005, Radiation research.

Efficient Production of Reactive Oxygen Species in Neural Precursor Cells after Exposure to 250 MeV Protons

J. Fike, C. Limoli, R. Rola, 2005, Radiation research.

Cell-density-dependent regulation of neural precursor cell function.

J. Fike, C. Limoli, Ting-Ting Huang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cytoskeleton-Associated Protein ) ( Activity-Regulated Arc Immediate-Early Gene Cranial Irradiation Alters the Behaviorally Induced

J. Fike, S. Rosi, M. Andres-Mach, 2008 .

Depletion of Neural Precursor Cells after Local Brain Irradiation is due to Radiation Dose to the Parenchyma, not the Vasculature

J. Fike, J. Hopewell, R. Rola, 2006, Radiation research.

Effects of Low Level Radiation exposure on Neurogenesis and Cognitive Function: Mechanisms and Prevention

J. Fike, 2005 .

Hyperthermia for Malignant Brain Tumors

P. Stauffer, J. Fike, P. Sneed, 1986 .

[Hyperthermia in malignant brain tumors. Interstitial microwave hyperthermia in a canine brain model].

P. Stauffer, J. Fike, P. Sneed, 1986, Neurologia medico-chirurgica.

Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist

J. Fike, Phillip C. Yang, Ting-Ting Huang, 2016, Experimental Neurology.

High-LET Radiation-Induced Response of Microvessels in the Hippocampus

J. Fike, L. Kubínová, X. Mao, 2010, Radiation research.

Anatomy of the beagle in cross-section: head and neck.

E. W. Bradley, J. Fike, B. Zook, 1981, American journal of veterinary research.

Effects of Proton and Combined Proton and 56Fe Radiation on the Hippocampus

Jacob Raber, Susanna Rosi, J. Fike, 2015, Radiation research.

Traumatic Injury to the Immature Brain Results in Progressive Neuronal Loss, Hyperactivity and Delayed Cognitive Impairments

J. Fike, D. Ferriero, J. Raber, 2006, Developmental Neuroscience.

Thermal distribution studies of helical coil microwave antennas for interstitial hyperthermia.

P. Stauffer, J. Fike, T. Satoh, 1988, International journal of radiation oncology, biology, physics.

Glutathione peroxidase overexpression does not rescue impaired neurogenesis in the injured immature brain

J. Fike, D. Ferriero, R. Rola, 2009, Journal of neuroscience research.

Comparative thermal dosimetry of interstitial microwave and radiofrequency-LCF hyperthermia.

P. Stauffer, J. Fike, T. Satoh, 1989, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Trauma‐induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation

J. Fike, A. Obenaus, J. Raber, 2012, Hippocampus.

Irradiation enhances hippocampus‐dependent cognition in mice deficient in extracellular superoxide dismutase

J. Fike, J. Raber, Ting-Ting Huang, 2011, Hippocampus.

Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation

J. Fike, Rikki S. Corniola, Ting-Ting Huang, 2012, Proceedings of the National Academy of Sciences.

60Co gamma and negative pi meson irradiation of microvasculature.

J. Fike, E. Gillette, 1978, International journal of radiation oncology, biology, physics.

. CT for measurement of regional cerebral blood Comparison of xenon-enhanced CT with ultrafast

J. Fike, G. T. Gobbel, C. E. Cann, 2022 .