J. O'Donnell

发表

Microwave attenuation of ethanol-induced interactions with noradrenergic neurotransmitter systems.

D. Hjeresen, A. Francendese, J. O'Donnell, 1989, Health physics.

Inhibition of Cyclic Nucleotide Phosphodiesterases to Regulate Memory

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2014 .

Anxiogenic-Like Behavioral Phenotype of Mice Deficient in Phosphodiesterase 4B (PDE4B)

J. O'Donnell, S. Jin, M. Conti, 2008, Neuropsychopharmacology.

Effects of noradrenergic lesions on the development of rolipram-sensitive, low-K(m), cyclic AMP specific phosphodiesterase in rat brain.

J. O'Donnell, K. Zhang, S. Farooqui, 1999, Brain research. Developmental brain research.

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness

Sabine Bahn, Bin Xu, J. O'Donnell, 2017, The Journal of Neuroscience.

Effects of clenbuterol on central beta-1 and beta-2 adrenergic receptors of the rat.

J. O'Donnell, A. Frazer, G. Ordway, 1987, The Journal of pharmacology and experimental therapeutics.

Inhibitor Binding to Type 4 Phosphodiesterase (PDE4) Assessed Using [3H]Piclamilast and [3H]Rolipram

J. O'Donnell, Yu Zhao, Han-Ting Zhang, 2003, Journal of Pharmacology and Experimental Therapeutics.

Discriminative stimulus effects of centrally administered isoproterenol in rats: mediation by beta-1 adrenergic receptors

J. O'Donnell, A. M. Crissman, M. Makhay, 2001, Psychopharmacology.

Ontogeny of rolipram-sensitive, low-K(m), cyclic AMP-specific phosphodiesterase in rat brain.

J. O'Donnell, K. Zhang, S. Farooqui, 1999, Brain research. Developmental brain research.

Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: Comparison with rolipram

J. O'Donnell, D. Dlaboga, Hassan Hajjhussein, 2006, Brain Research.

Effects of Repeated Treatment with Phosphodiesterase-4 Inhibitors on cAMP Signaling, Hippocampal Cell Proliferation, and Behavior in the Forced-Swim Test

J. O'Donnell, J. O'Callaghan, Lan Xiao, 2011, Journal of Pharmacology and Experimental Therapeutics.

Modulation of MK-801-induced behaviour by noradrenergic agents in mice

J. O'Donnell, J. Kelly, B. Leonard, 2001, Psychopharmacology.

Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice

J. O'Donnell, Qiang Wu, Ying Xu, 2019, Journal of psychopharmacology.

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

J. O'Donnell, Ying Xu, Jianchun Pan, 2013, Metabolic Brain Disease.

Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2018, Front. Aging Neurosci..

Discriminative stimulus properties of haloperidol

J. O'Donnell, J. McElroy, J. Stimmel, 1989 .

Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats

J. O'Donnell, Yu Zhao, M. Vivo, 2006, Psychopharmacology.

Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes

J. O'Donnell, D. Dlaboga, G. Konat, 2009, Metabolic Brain Disease.

Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior

Xiongwei Zhu, J. O'Donnell, Ying Xu, 2020, Psychopharmacology.

The neuroprotective and antidepressant‐like effects of Hcyb1, a novel selective PDE2 inhibitor

J. O'Donnell, Xia Zhu, Han-Ting Zhang, 2018, CNS neuroscience & therapeutics.

The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition

J. O'Donnell, Ying Xu, Xiaoxin Yin, 2019, Neuropharmacology.

The biochemical basis of neuropharmacology, sixth edition. By J R. Cooper, F. E. Bloom and R. H. Roth. Oxford University Press, New York. 454 pp. £35 (£15 pbk.)

J. O'Donnell, 1992 .

Acid-sensing ion channel 3 deficiency increases inflammation but decreases pain behavior in murine arthritis.

J. O'Donnell, G. Firestein, K. Sluka, 2013, Arthritis and rheumatism.

Altered thermoregulatory responses to clonidine in streptozotocin‐diabetic rats

J. O'Donnell, T. Bányász, T. Kovács, 1996, British journal of pharmacology.

Protective effects of phosphodiesterase 2 inhibitor against Aβ1-42 induced neuronal toxicity

Wei Wang, Xiongwei Zhu, J. O'Donnell, 2022, Neuropharmacology.

A Toxicokinetic Study of Nickel‐Induced Immunosuppression in Rats

J. O'Donnell, J. Kelly, T. Connor, 2003, Immunopharmacology and immunotoxicology.

Protective effects of phosphodiesterase 2 inhibitor on depression- and anxiety-like behaviors: Involvement of antioxidant and anti-apoptotic mechanisms

J. O'Donnell, A. Nadeem, Ying Xu, 2014, Behavioural Brain Research.

Facilitation of noradrenaline release from rat brain slices by \-adrenoceptors

J. O'Donnell, K. Murugaiah, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

A study of VitalView™ for behavioural and physiological monitoring in laboratory rats

James M. O'Donnell, Andrew Harkin, John P. Kelly, 2002, Physiology & Behavior.

William Harvey Research Conference on PDE inhibitors: drugs with an expanding range of therapeutic uses

J. O'Donnell, 2000, Expert Opinion on Investigational Drugs.

Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

J. O'Donnell, M. Vivo, Han-Ting Zhang, 2005, Psychopharmacology.

Antidepressant-like Profile and Reduced Sensitivity to Rolipram in Mice Deficient in the PDE4D Phosphodiesterase Enzyme

J. O'Donnell, S. Jin, M. Conti, 2002, Neuropsychopharmacology.

Dual inhibitors of phosphodiesterase-4 and serotonin reuptake.

J. O'Donnell, J. Cashman, Han-Ting Zhang, 2009, Journal of medicinal chemistry.

Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures

J. O'Donnell, L. Chandler, Hassan Hajjhussein, 2007, Brain Research.

Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.

J. O'Donnell, Neesha U. Suvarna, 2002, The Journal of pharmacology and experimental therapeutics.

Inhibition of Cyclic AMP Phosphodiesterase (PDE4) Reverses Memory Deficits Associated with NMDA Receptor Antagonism

J. O'Donnell, Han-Ting Zhang, L. Chandler, 2000, Neuropsychopharmacology.

Phosphodiesterases: CNS Functions and Diseases

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2017, Advances in Neurobiology.

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4).

J. O'Donnell, Han-Ting Zhang, James M O'Donnell, 2004, Trends in pharmacological sciences.

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

G. Wang, J. O'Donnell, Ying Xu, 2016, Oncotarget.

Behavioral consequences of activation of beta adrenergic receptors by clenbuterol: Evidence for mediation by the central nervous system

J. O'Donnell, 1988, Brain Research Bulletin.

Regular physical activity prevents development of chronic pain and activation of central neurons.

J. O'Donnell, K. Sluka, J. Danielson, 2013, Journal of applied physiology.

Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2011, Handbook of experimental pharmacology.

Inhibition of the Phosphodiesterase 4 (PDE4) Enzyme Reverses Memory Deficits Produced by Infusion of the MEK Inhibitor U0126 into the CA1 Subregion of the Rat Hippocampus

J. O'Donnell, Yu Zhao, Han-Ting Zhang, 2004, Neuropsychopharmacology.

Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate.

J M O'Donnell, J. O'Donnell, James M. O'Donnell, 1993, The Journal of pharmacology and experimental therapeutics.

The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2017, Advances in neurobiology.

The roles of phosphodiesterase 2 in the central nervous and peripheral systems.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2014, Current pharmaceutical design.

Cyclic GMP–mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice

J. O'Donnell, C. Zhan, Lindsay M. Lueptow, 2015, Psychopharmacology.

Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice

J. O'Donnell, M. Karayiorgou, Clay Lacefield, 2011, Proceedings of the National Academy of Sciences.

Norepinephrine Transporter Regulation Mediates the Long-Term Behavioral Effects of the Antidepressant Desipramine

D. Morilak, J. O'Donnell, C. Bondi, 2008, Neuropsychopharmacology.

Novel Therapeutic Targets in Depression and Anxiety: Antioxidants as a Candidate Treatment

J. O'Donnell, Ying Xu, Chuang Wang, 2014, Current neuropharmacology.

Frontiers in Clinical Drug Research - Alzheimer Disorders

K. Jellinger, J. O'Donnell, M. Crespo-Alonso, 2015 .

Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.

R. F. Campbell, M. Gurney, J. O'Donnell, 2019, Journal of medicinal chemistry.

Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

M. Gurney, J. O'Donnell, R. Salvi, 2018, Neuropsychopharmacology.

Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain

J. O'Donnell, J. Cherry, S. Farooqui, 2000, Brain Research.

Single housing‐induced effects on cognitive impairment and depression‐like behavior in male and female mice involve neuroplasticity‐related signaling

J. O'Donnell, Christopher Banker, Yulu Wang, 2019, The European journal of neuroscience.

Association of Changes in Norepinephrine and Serotonin Transporter Expression with the Long-Term Behavioral Effects of Antidepressant Drugs

J. O'Donnell, M. Millan, Zaorui Zhao, 2009, Neuropsychopharmacology.

The effect of repeated desipramine administration on water intake in rats

L. Seiden, J. O'Donnell, D. Rider, 2004, Psychopharmacology.

Effects of monoamine oxidase inhibitors on performance during differential reinforcement of low response rate

L. Seiden, J. O'Donnell, 2004, Psychopharmacology.

Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2018, Psychopharmacology.

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2015, Neurobiology of Aging.

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2013, The international journal of neuropsychopharmacology.

Anxiolytic Effects of Phosphodiesterase-2 Inhibitors Associated with Increased cGMP Signaling

J. O'Donnell, A. Hamza, C. Zhan, 2009, Journal of Pharmacology and Experimental Therapeutics.

Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice

J. O'Donnell, A. Nadeem, Anbrin Masood, 2008, Journal of Pharmacology and Experimental Therapeutics.

Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats

J. O'Donnell, Han-Ting Zhang, 2000, Psychopharmacology.

Microwave attenuation of ethanol-induced hypothermia: ethanol tolerance, time course, exposure duration, and dose response studies.

D L Hjeresen, A Francendese, J M O'Donnell, 1988, Bioelectromagnetics.

Intruder-evoked aggression in isolated and nonisolated mice: Effects of psychomotor stimulants and l-Dopa

J. O'Donnell, K. Miczek, 1978, Psychopharmacology.

Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum

J. O'Donnell, D. Dlaboga, Hassan Hajjhussein, 2008, Neuropharmacology.

Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2015, Scientific Reports.

Noradrenergic Activity Differentially Regulates the Expression of Rolipram‐Sensitive, High‐Affinity Cyclic AMP Phosphodiesterase (PDE4) in Rat Brain

J. O'Donnell, M. Houslay, M. Conti, 1997, Journal of neurochemistry.

Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor

M. Gurney, J. O'Donnell, Ying Xu, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Agonist interactions with beta adrenergic receptors in rat brain.

J. O'Donnell, A. Frazer, B. Wolfe, 1984, The Journal of pharmacology and experimental therapeutics.

Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 (PDE4) inhibitor rolipram on behavior depend on cyclic AMP-response element binding protein (CREB)-mediated neurogenesis in the hippocampus

J. O'Donnell, Han-Ting Zhang, Ying Huang, 2009, Neuropsychopharmacology.

Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences.

J. O'Donnell, Rui Wang, Ying Xu, 2013, Journal of psychiatric research.

Effects of Antidepressants in Rats Trained to Discriminate Centrally Administered Isoproterenol

J. O'Donnell, A. M. Crissman, 2002, Journal of Pharmacology and Experimental Therapeutics.

Effects of Antidepressants in Rats Trained to Discriminate the Beta-2 Adrenergic Agonist Clenbuterol

J. O'Donnell, Malath M Makhay, 1999, Pharmacology Biochemistry and Behavior.

Behavioral effects of beta adrenergic agonists and antidepressant drugs after down-regulation of beta-2 adrenergic receptors by clenbuterol.

J. O'Donnell, 1990, The Journal of pharmacology and experimental therapeutics.

Inhibitor binding to type 4 phosphodiesterase (PDE4) assessed using [3H]piclamilast and [3H]rolipram.

J. O'Donnell, Yu Zhao, Han-Ting Zhang, 2003, The Journal of pharmacology and experimental therapeutics.

Antidepressant effects assessed using behavior maintained under a differential-reinforcement-of-low-rate (DRL) operant schedule

G. Marek, L. Seiden, J. O'Donnell, 2005, Neuroscience & Biobehavioral Reviews.

Cyclic GMP–mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice

J. O'Donnell, C. Zhan, Lindsay M. Lueptow, 2016, Psychopharmacology.

Effects of Repeated Antidepressant Treatment on Type 4A Phosphodiesterase (PDE4A) in Rat Brain

J. O'Donnell, K. Jackson, Ying Ye, 2000, Journal of neurochemistry.

A Novel PDE4D Inhibitor BPN14770 Reverses Scopolamine-Induced Cognitive Deficits via cAMP/SIRT1/Akt/Bcl-2 Pathway

M. Gurney, J. O'Donnell, Ying Xu, 2020, Frontiers in Cell and Developmental Biology.

Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System

M. Gurney, J. O'Donnell, Ying Xu, 2017, Scientific Reports.

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

J. O'Donnell, M. Conti, Han-Ting Zhang, 2011, The Journal of Neuroscience.

Development of rolipram-sensitive, cyclic AMP phosphodiesterase (PDE4) in rat primary neuronal cultures.

J. O'Donnell, M. Houslay, L. Chandler, 2001, Brain research. Developmental brain research.

Diminished Noradrenergic Stimulation Reduces the Activity of Rolipram‐Sensitive, High‐Affinity Cyclic AMP Phosphodiesterase in Rat Cerebral Cortex

J. O'Donnell, Y. Ye, 1996, Journal of neurochemistry.

Postsynaptic α-2 Adrenergic Receptors are Critical for the Antidepressant-Like Effects of Desipramine on Behavior

J. O'Donnell, Han-Ting Zhang, Ying Huang, 2009, Neuropsychopharmacology.

Neuroendocrine response to clonidine and 8‐OH‐DPAT in rats following chronic administration of desipramine or sertraline

J. O'Donnell, M. Grealy, 1992, British journal of pharmacology.

Test Conditions Influence the Response to a Drug Challenge in Rodents

J. O'Donnell, J. Kelly, B. Leonard, 2000, Pharmacology Biochemistry and Behavior.

Comparison of the effects of isoproterenol administered into the hippocampus, frontal cortex, or amygdala on behavior of rats maintained by differential reinforcement of low response rate

J. O'Donnell, Han-Ting Zhang, J. Wilkins, 2001, Psychopharmacology.

Effects of centrally acting beta adrenergic agonists on discrete trial conditioned avoidance behavior in rats

J. O'Donnell, J. McElroy, J. Stimmel, 2004, Psychopharmacology.

Behavioral Effects of Family-Selective Inhibitors of Cyclic Nucleotide Phosphodiesterases

J. O'Donnell, S. Frith, 1999, Pharmacology Biochemistry and Behavior.

Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats

J. O'Donnell, Han-Ting Zhang, Ying Huang, 2005, Psychopharmacology.

Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats

J. O'Donnell, M. Houslay, M. Makhay, 2001, Psychopharmacology.

Pharmacological Characterization of the Discriminative Stimulus Effects of Clenbuterol in Rats

J. O'Donnell, 1997, Pharmacology Biochemistry and Behavior.

Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol.

J. O'Donnell, J. Wilkins, S. Frith, 1994, The Journal of pharmacology and experimental therapeutics.

Differential-reinforcement-of-low-rate 72-second schedule: selective effects of antidepressant drugs.

L. Seiden, J. O'Donnell, 1983, The Journal of pharmacology and experimental therapeutics.

No tolerance to antiaggressive effect of d-amphetamine in mice

J. O'Donnell, K. Miczek, 2004, Psychopharmacology.

Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior

Xiongwei Zhu, J. O'Donnell, Ying Xu, 2018, Neuropharmacology.

Antidepressant-Induced Increase in High-Affinity Rolipram Binding Sites in Rat Brain: Dependence on Noradrenergic and Serotonergic Function

J. O'Donnell, Yu Zhao, Han-Ting Zhang, 2003, Journal of Pharmacology and Experimental Therapeutics.

Animal models of depression and neuroplasticity: assessing drug action in relation to behavior and neurogenesis.

J. O'Donnell, Ying Xu, W. O. Ogle, 2012, Methods in molecular biology.

Facilitation of norepinephrine release from cerebral cortex is mediated by beta 2-adrenergic receptors.

J. O'Donnell, K. Murugaiah, 1995, Life sciences.

Antagonism of the antidepressant-like effects of clenbuterol by central administration of β-adrenergic antagonists in rats

J. O'Donnell, Han-Ting Zhang, Ying Huang, 2003, Psychopharmacology.

Differential sensitivity to the effects of albuterol on locomotor activity and operant behavior

J. O'Donnell, 2005, Psychopharmacology.

Antagonism of the responses to isoproterenol in the rat hippocampal slice with subtype-selective antagonists.

J. O'Donnell, J. Fowler, 1988, European journal of pharmacology.

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

J. O'Donnell, Ying Xu, Jianchun Pan, 2013, Metabolic Brain Disease.

Physiological and behavioral responses to stress: what does a rat find stressful?

J. O'Donnell, J. Kelly, T. Connor, 2002, Lab animal.

Evidence for Global Reduction in Brain Cyclic Adenosine Monophosphate Signaling in Depression

J. O'Donnell, Ying Xu, 2012, Biological Psychiatry.

Effects of the beta-2 adrenergic agonist zinterol on DRL behavior and locomotor activity

J. O'Donnell, 2005, Psychopharmacology.

Antisense oligonucleotides fail to inhibit the expression of central beta adrenergic receptors.

J. O'Donnell, K. Zhang, 1997, Research communications in molecular pathology and pharmacology.

Memory enhancement induced by PDE2 knockdown in an Alzheimer's disease model of mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2016 .

Altered effects of desipramine on operant performance after 6-hydroxydopamine-induced depletion of brain dopamine or norepinephrine.

L. Seiden, J. O'Donnell, 1984, The Journal of pharmacology and experimental therapeutics.

Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat

J. O'Donnell, M. Grealy, 1991, British journal of pharmacology.

Cardiac excitation-contraction coupling in the portal hypertensive rat.

J. O'Donnell, S. Roerig, J. O'donnell, 2000, American journal of physiology. Gastrointestinal and liver physiology.