R. N. Harty

发表

A Host-Oriented Inhibitor of Junin Argentine Hemorrhagic Fever Virus Egress

Michael S. Lee, Jianhong Lu, Ziying Han, 2014, Journal of Virology.

Transcriptional analysis of the UL1 gene of equine herpesvirus 1: a gene conserved in the genome of defective interfering particles.

R. N. Harty, D. O’Callaghan, R. Yalamanchili, 1991, Virology.

Expression of an equine herpesvirus 1 ICP22/ICP27 hybrid protein encoded by defective interfering particles associated with persistent infection

R. N. Harty, M. Chen, D. O’Callaghan, 1996, Journal of virology.

Transcriptional and translational analyses of the UL2 gene of equine herpesvirus 1: a homolog of UL55 of herpes simplex virus type 1 that is maintained in the genome of defective interfering particles

R. N. Harty, D. O’Callaghan, V. R. Holden, 1993, Journal of virology.

Identification and expression of the UL1 gene product of equine herpesvirus 1.

R. N. Harty, D. O’Callaghan, 1992, Virus research.

An early gene maps within and is 3' coterminal with the immediate-early gene of equine herpesvirus 1

R. N. Harty, D. O’Callaghan, D. O'callaghan, 1991, Journal of virology.

SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1

R. N. Harty, M. Sudol, M. Bedford, 2021, PloS one.

In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences

R. N. Harty, A. García-Sastre, E. Carnero, 2012, Infectious diseases.

VPS-4of Host Proteins TSG101 and Independently as Late Budding Domains: the Ebola Virus VP40 Protein Function Overlapping Motifs (PTAP and PPEY) within

R. N. Harty, N. Wright, Jillian M. Licata, 2014 .

No exit: targeting the budding process to inhibit filovirus replication.

R. N. Harty, 2009, Antiviral research.

Detection and intracellular localization of equine herpesvirus 1 IR1 and IR2 gene products by using monoclonal antibodies

R. N. Harty, D. O’Callaghan, R. H. Smith, 1995, Journal of virology.

Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses

Michael S. Lee, Jianhong Lu, Ziying Han, 2014, Journal of Virology.

Late Domain Function Identified in the Vesicular Stomatitis Virus M Protein by Use of Rhabdovirus-Retrovirus Chimeras

R. N. Harty, P. Palese, J. Wills, 1999, Journal of Virology.

Vaccinia virus-free recovery of vesicular stomatitis virus.

R. N. Harty, M. Schnell, N. Wright, 2001, Journal of molecular microbiology and biotechnology.

Budding of PPxY-Containing Rhabdoviruses Is Not Dependent on Host Proteins TGS101 and VPS4A

R. N. Harty, M. Schnell, T. Irie, 2004, Journal of Virology.

Contribution of Ebola Virus Glycoprotein, Nucleoprotein, and VP24 to Budding of VP40 Virus-Like Particles

Ziying Han, R. N. Harty, Reed F. Johnson, 2004, Journal of Virology.

Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress

Ziying Han, G. Ruthel, B. Freedman, 2018, Diseases.

Functional Analysis of Late-Budding Domain Activity Associated with the PSAP Motif within the Vesicular Stomatitis Virus M Protein

R. N. Harty, M. Whitt, T. Irie, 2004, Journal of Virology.

A Proline-Rich Motif within the Matrix Protein of Vesicular Stomatitis Virus and Rabies Virus Interacts with WW Domains of Cellular Proteins: Implications for Viral Budding

R. N. Harty, M. Sudol, P. Palese, 1999, Journal of Virology.

Budding of Virus-Like Particles Stability, Localization, and Subsequent Virus VP40 Proteins Are Important for Conserved Motifs within Ebola and Marburg

Yuliang Liu, R. N. Harty, Yongan Zhang, 2011 .

Biochemical and Functional Characterization of the Ebola Virus VP24 Protein: Implications for a Role in Virus Assembly and Budding

Ziying Han, R. N. Harty, J. Sunyer, 2003, Journal of Virology.

Packaging of actin into Ebola virus VLPs

Ziying Han, R. N. Harty, 2005, Virology Journal.

SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1

R. N. Harty, M. Sudol, M. Bedford, 2020, bioRxiv.

Ebola Virus VP35-VP40 Interaction Is Sufficient for Packaging 3E-5E Minigenome RNA into Virus-Like Particles

R. N. Harty, Reed F. Johnson, Sarah E. McCarthy, 2006, Journal of Virology.

Bimolecular Complementation to Visualize Filovirus VP40-Host Complexes in Live Mammalian Cells: Toward the Identification of Budding Inhibitors

Michael S. Lee, Yuliang Liu, M. A. Olson, 2011, Advances in virology.

Characterization of the myristylated polypeptide encoded by the UL1 gene that is conserved in the genome of defective interfering particles of equine herpesvirus 1

R. N. Harty, D. O’Callaghan, G. Caughman, 1993, Journal of virology.

Cigarette smoking products suppress anti‐viral effects of Type I interferon via phosphorylation‐dependent downregulation of its receptor

R. N. Harty, S. Fuchs, Wei-Chun HuangFu, 2008, FEBS letters.

AnEarlyGeneMapswithin andIs3'Coterminal withthe Immediate-Early GeneofEquineHerpesvirus 1

R. N. Harty, 1991 .

A Chimeric Influenza Virus Expressing an Epitope of Outer Membrane Protein F of Pseudomonas aeruginosa Affords Protection against Challenge with P. aeruginosa in a Murine Model of Chronic Pulmonary Infection

R. N. Harty, A. García-Sastre, P. Palese, 1998, Infection and Immunity.

Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy.

R. N. Harty, R. Vile, S. Russell, 2010, Human gene therapy.

Modifications of the PSAP region of the matrix protein lead to attenuation of vesicular stomatitis virus in vitro and in vivo.

R. N. Harty, A. García-Sastre, E. Carnero, 2007, The Journal of general virology.

WW- and SH3-domain interactions with Epstein-Barr virus LMP2A.

R. N. Harty, R. Longnecker, M. Merchant, 2000, Experimental cell research.

Chimeric influenza viruses incorporating epitopes of outer membrane protein F as a vaccine against pulmonary infection with Pseudomonas aeruginosa.

R. N. Harty, A. García-Sastre, P. Palese, 1997, Behring Institute Mitteilungen.

Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology

R. N. Harty, Reed F. Johnson, P. Bell, 2006, Virology Journal.

PPEY Motif within the Rabies Virus (RV) Matrix Protein Is Essential for Efficient Virion Release and RV Pathogenicity

R. N. Harty, J. Orenstein, C. Wirblich, 2008, Journal of Virology.

Angiomotin regulates budding and spread of Ebola virus

Ziying Han, G. Ruthel, B. Freedman, 2020, The Journal of Biological Chemistry.

Modular mimicry and engagement of the Hippo pathway by Marburg virus VP40: Implications for filovirus biology and budding

Ziying Han, G. Ruthel, B. Freedman, 2020, PLoS pathogens.

Host IQGAP1 and Ebola Virus VP40 Interactions Facilitate Virus-Like Particle Egress

Jianhong Lu, Ziying Han, Yuliang Liu, 2013, Journal of Virology.

Characterization of filovirus protein-protein interactions in mammalian cells using bimolecular complementation.

Yuliang Liu, R. N. Harty, Sasha Stone, 2011, The Journal of infectious diseases.

Small Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block 1

Michael S. Lee, Jianhong Lu, Ziying Han, 2014 .

L-Domain Flanking Sequences Are Important for Host Interactions and Efficient Budding of Vesicular Stomatitis Virus Recombinants

R. N. Harty, T. Irie, 2005, Journal of Virology.

Rabies virus assembly and budding.

R. N. Harty, A. Okumura, 2011, Advances in virus research.

III . THE CENTRAL ROLE OF M AND SUPPORTING ROLE OF G IN RABV BUDDING

R. N. Harty, A. Okumura, 2011 .

RHABDOVIRUSES AND APOPTOSIS

R. N. Harty, Jillian M. Licata, 2003, International reviews of immunology.

Quinoxaline-based inhibitors of Ebola and Marburg VP40 egress.

Ziying Han, G. Ruthel, B. Freedman, 2016, Bioorganic & medicinal chemistry letters.

Identification and characterization of an equine herpesvirus 1 late gene encoding a potential zinc finger.

R. N. Harty, D. O’Callaghan, V. R. Holden, 1992, Virology.

The IR3 gene of equine herpesvirus type 1: a unique gene regulated by sequences within the intron of the immediate-early gene.

R. N. Harty, D. O’Callaghan, V. R. Holden, 1992, DNA sequence : the journal of DNA sequencing and mapping.

Antiviral Activity of Innate Immune Protein ISG15

R. N. Harty, P. Pitha, A. Okumura, 2009, Journal of Innate Immunity.

Mapping the termini and intron of the spliced immediate-early transcript of equine herpesvirus 1

R. N. Harty, D. O’Callaghan, F. Grundy, 1989, Journal of virology.

The YPLGVG sequence of the Nipah virus matrix protein is required for budding

C. Broder, Ziying Han, R. N. Harty, 2008, Virology Journal.

Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4

Ziying Han, R. N. Harty, N. Wright, 2003, Journal of Virology.

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

Atsushi Okumura, R. N. Harty, A. Yoshimura, 2009, Journal of Virology.

Micronutrient Improvement of Epithelial Barrier Function in Various Disease States: A Case for Adjuvant Therapy

R. N. Harty, J. M. Mullin, K. Diguilio, 2022, International journal of molecular sciences.

Viral and host proteins that modulate filovirus budding.

Yuliang Liu, R. N. Harty, 2010, Future virology.

Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention

J. Dye, Jianhong Lu, Ziying Han, 2015, PLoS pathogens.

Chimeric animal and plant viruses expressing epitopes of outer membrane protein F as a combined vaccine against Pseudomonas aeruginosa lung infection.

R. N. Harty, A. García-Sastre, P. Palese, 2000, FEMS immunology and medical microbiology.

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

R. N. Harty, P. Pitha, A. Okumura, 2008, Proceedings of the National Academy of Sciences.

Identification and characterization of the ICP22 protein of equine herpesvirus 1

R. N. Harty, G. Caughman, V. R. Holden, 1994, Journal of virology.

The multifunctional Ebola virus VP40 matrix protein is a promising therapeutic target.

Ziying Han, G. Ruthel, B. Freedman, 2015, Future virology.

Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress

G. Ruthel, B. Freedman, R. N. Harty, 2021, Journal of Virology.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress

Ziying Han, G. Ruthel, B. Freedman, 2017, Journal of Virology.

Correction: Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ziying Han, R. N. Harty, M. Sudol, 2017, PLoS pathogens.

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ziying Han, R. N. Harty, M. Sudol, 2017, PLoS pathogens.

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding

Ziying Han, R. N. Harty, M. Sudol, 2016, Journal of Virology.

ITCH E 3 Ubiquitin Ligase Interacts with Ebola Virus VP 40 To Regulate Budding

Ziying Han, R. N. Harty, M. Sudol, 2016 .

Rhabdoviruses and the Cellular Ubiquitin-Proteasome System: a Budding Interaction

R. N. Harty, J. Huibregtse, M. Whitt, 2001, Journal of Virology.

The NS3 Protein of Bluetongue Virus Exhibits Viroporin-like Properties*

Ziying Han, R. N. Harty, 2004, Journal of Biological Chemistry.

Compound FC-10696 Inhibits Egress of Marburg Virus

Ziying Han, B. Freedman, R. N. Harty, 2021, Antimicrobial agents and chemotherapy.

Compound FC-10696 Inhibits Egress and Spread of Marburg Virus

Ziying Han, B. Freedman, R. N. Harty, 2021, bioRxiv.

A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding.

R. N. Harty, J. Huibregtse, G. Wang, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Measles virus phosphoprotein (P) requires the NH2- and COOH-terminal domains for interactions with the nucleoprotein (N) but only the COOH terminus for interactions with itself.

R. N. Harty, P. Palese, Ronald N Harty, 1995, The Journal of general virology.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection

M. Katze, R. N. Harty, Y. Kawaoka, 2015, Journal of Virology.

Phospholipid Scramblase 1 Potentiates the Antiviral Activity of Interferon

R. N. Harty, B. Williams, R. Silverman, 2004, Journal of Virology.

Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection

D. Weiner, R. N. Harty, R. Ricciardi, 2021, Molecular Therapy.

ICP22 homolog of equine herpesvirus 1: expression from early and late promoters

R. N. Harty, V. R. Holden, R. Yalamanchili, 1992, Journal of virology.

Role for Amino Acids 212KLR214 of Ebola Virus VP40 in Assembly and Budding

R. N. Harty, Reed F. Johnson, J. Sunyer, 2007, Journal of Virology.

Conserved Motifs within Ebola and Marburg Virus VP40 Proteins Are Important for Stability, Localization, and Subsequent Budding of Virus-Like Particles

Yuliang Liu, R. N. Harty, A. Okumura, 2009, Journal of Virology.

Calcium and filoviruses: a budding relationship.

B. Freedman, R. N. Harty, 2016, Future microbiology.

ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.

Ziying Han, Yuliang Liu, Wenbo Liu, 2015, The Journal of infectious diseases.

Influence of calcium/calmodulin on budding of Ebola VLPs: implications for the involvement of the Ras/Raf/MEK/ERK pathway

Ziying Han, R. N. Harty, 2007, Virus Genes.

Viruses go modular

R. N. Harty, M. Sudol, Hao Fan, 2020, The Journal of Biological Chemistry.

Ubiquitin Ligase SMURF2 Interacts with Filovirus VP40 and Promotes Egress of VP40 VLPs

R. N. Harty, M. Bedford, J. Cassel, 2021, Viruses.

WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles

G. Ruthel, B. Freedman, R. N. Harty, 2022, Journal of virology.

WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 VLPs

G. Ruthel, B. Freedman, R. N. Harty, 2021, bioRxiv.

Identification and transcriptional analyses of the UL3 and UL4 genes of equine herpesvirus 1, homologs of the ICP27 and glycoprotein K genes of herpes simplex virus

R. N. Harty, V. R. Holden, Y. Zhao, 1992, Journal of virology.

Calcitriol modifies tight junctions, improves barrier function, and reduces TNF‐α‐induced barrier leak in the human lung‐derived epithelial cell culture model, 16HBE 14o‐

R. N. Harty, J. M. Mullin, K. Diguilio, 2023, Physiological reports.

Phage display identification of nanomolar ligands for human NEDD4-WW3: Energetic and dynamic implications for the development of broad-spectrum antivirals.

Philip M. Kim, Jose C. Martínez, Ziying Han, 2022, International journal of biological macromolecules.

Ebola virus mediated infectivity is restricted in canine and feline cells.

C. Vite, Ziying Han, G. Ruthel, 2016, Veterinary microbiology.

Chaperone-assisted selective autophagy targets filovirus VP40 as a client and restricts egress of virus particles

R. N. Harty, Jingjing Liang, O. Shtanko, 2023, Proceedings of the National Academy of Sciences of the United States of America.

A luciferase-based budding assay for Ebola virus.

R. N. Harty, Sarah E. McCarthy, Jillian M. Licata, 2006, Journal of Virological Methods.

Permeabilization of the plasma membrane by Ebola virus GP2

Ziying Han, R. N. Harty, J. Paragas, 2007, Virus Genes.

Functional characterization of Ebola virus L-domains using VSV recombinants.

R. N. Harty, T. Irie, Jillian M. Licata, 2005, Virology.

Cytopathogenesis of Vesicular Stomatitis Virus Is Regulated by the PSAP Motif of M Protein in a Species-Dependent Manner

Yuliang Liu, R. N. Harty, A. García-Sastre, 2012, Viruses.

Contrasting effects of filamin A and B proteins in modulating filovirus entry

R. N. Harty, O. Sunyer, Jingjing Liang, 2023, PLoS pathogens.

A Proline-Rich Motif within the Matrix Protein of Vesicular Stomatitis Virus and Rabies Virus Interacts with WW Domains of Cellular Proteins: Implications for Viral Budding

R. N. Harty, M. Sudol, P. Palese, 1999, Journal of Virology.