L. BenMohamed

发表

HLA-A02:01–Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpes

Ruchi Srivastava, Arif A. Khan, D. Spencer, 2015, The Journal of Immunology.

Track A Basic Science

S. Sugden, D. Hazuda, F. Pereyra, 2012, Journal of the International AIDS Society.

Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine.

D. Spencer, L. BenMohamed, F. Lemonnier, 2014, Human immunology.

Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis.

S. Wechsler, L. BenMohamed, Clinton Jones, 2007, Virology.

Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines

S. Prakash, Ruchi Srivastava, A. Nesburn, 2020 .

Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines

S. Prakash, Ruchi Srivastava, A. Nesburn, 2020, bioRxiv.

Airway epithelial cells enhance the immunogenicity of human myeloid dendritic cells under steady state

L. BenMohamed, A. Agrawal, S. Agrawal, 2017, Clinical and experimental immunology.

NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2019, Front. Immunol..

Nasolacrimal Duct Closure Modulates Ocular Mucosal and Systemic CD4+ T-Cell Responses Induced following Topical Ocular or Intranasal Immunization

A. Nesburn, S. Wechsler, L. BenMohamed, 2010, Clinical and Vaccine Immunology.

Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine.

L. BenMohamed, M. G. Finn, Xuefei Huang, 2015, ACS chemical biology.

Linear and Branched Glyco-Lipopeptide Vaccines Follow Distinct Cross-Presentation Pathways and Generate Different Magnitudes of Antitumor Immunity

A. Nesburn, L. BenMohamed, G. Dasgupta, 2010, PloS one.

Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes

L. BenMohamed, G. Dasgupta, O. Renaudet, 2009, Cancer Immunology, Immunotherapy.

Towards a Self‐Adjuvanting Multivalent B and T cell Epitope Containing Synthetic Glycolipopeptide Cancer Vaccine

L. BenMohamed, G. Dasgupta, O. Renaudet, 2008, ChemMedChem.

HLA-A*0201-Restricted CD8+ Cytotoxic T Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein D1

K. Lamberth, S. Buus, A. Nesburn, 2008, The Journal of Immunology.

A. Nesburn, L. BenMohamed, A. Agrawal, 2014, Ocular immunology and inflammation.

Simplex Virus Glycoprotein D Lymphocyte Epitopes Identified from Herpes Cytotoxic T + HLA-A*0201-Restricted CD8

K. Lamberth, S. Buus, A. Nesburn, 2007 .

Cytokine Profiling in Patients with VCP‐Associated Disease

L. BenMohamed, V. Kimonis, F. Zaldivar, 2014, Clinical and translational science.

Title Cytokine Profiling in Patients with VCP-Associated Disease Permalink

L. BenMohamed, Veeral Katheria, Prachi Rana, 2022 .

New concepts in herpes simplex virus vaccine development: notes from the battlefield

A. Nesburn, S. Wechsler, L. BenMohamed, 2009, Expert review of vaccines.

Identification of Novel Immunodominant CD4+ Th1-Type T-Cell Peptide Epitopes from Herpes Simplex Virus Glycoprotein D That Confer Protective Immunity

A. Nesburn, S. Wechsler, L. BenMohamed, 2003, Journal of Virology.

A Fully Synthetic Therapeutic Vaccine Candidate Targeting Carcinoma-Associated Tn Carbohydrate Antigen Induces Tumor-Specific Antibodies in Nonhuman Primates

L. BenMohamed, C. Leclerc, S. Bay, 2004, Cancer Research.

HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway

L. BenMohamed, J. Izopet, E. Bahraoui, 2015, PloS one.

Title HIV-1 Tat protein induces production of proinflammatory cytokines by human dendritic cells and monocytes / macrophages through engagement of TLR 4-MD 2-CD 14 complex and activation of NF-κB pathway

L. BenMohamed, J. Izopet, E. Bahraoui, 2015 .

Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use.

L. BenMohamed, C. Leclerc, S. Bay, 2003, The journal of peptide research : official journal of the American Peptide Society.

Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes

S. Prakash, Ruchi Srivastava, H. Vahed, 2020, Scientific Reports.

Laser Adjuvant-Assisted Peptide Vaccine Promotes Skin Mobilization of Dendritic Cells and Enhances Protective CD8+ TEM and TRM Cell Responses against Herpesvirus Infection and Disease

Patricia P. Lopes, Thanh T. Pham, A. Nesburn, 2018, Journal of Virology.

CD25 “Natural” Regulatory T Cells Are Abundant in Rabbit Conjunctiva and Suppress Virus-Speciﬁc CD4 and CD8 (cid:1) Effector T Cells during Ocular Herpes Infection (cid:1)

A. Nesburn, S. Wechsler, L. BenMohamed, 2007 .

Developing an asymptomatic mucosal herpes vaccine: the present and the future.

A. Nesburn, S. Wechsler, L. BenMohamed, 2010, Future microbiology.

A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity.

L. BenMohamed, O. Renaudet, M. Fiore, 2014, Angewandte Chemie.

Asymptomatic HLA-A*02:01–Restricted Epitopes from Herpes Simplex Virus Glycoprotein B Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice against Ocular Herpes

J. Sidney, A. Sette, Arif A. Khan, 2013, The Journal of Immunology.

Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4+ TEM Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in “Humanized” HLA-DR Transgenic Mice

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2020, Journal of Virology.

Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection

Ruchi Srivastava, Arif A. Khan, H. Vahed, 2016, Journal of Virology.

The Simplex Virus Type 1 Latency-Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells

A. Nesburn, S. Wechsler, L. BenMohamed, 2012 .

A Novel Herpes Simplex Virus Type 1 Transcript (AL-RNA) Antisense to the 5′ End of the Latency-Associated Transcript Produces a Protein in Infected Rabbits

A. Nesburn, S. Wechsler, L. BenMohamed, 2002, Journal of Virology.

High Frequency of Gamma Interferon-Producing PLZFloRORγtlo Invariant Natural Killer 1 Cells Infiltrating Herpes Simplex Virus 1-Infected Corneas Is Associated with Asymptomatic Ocular Herpesvirus Infection

S. Prakash, Ruchi Srivastava, H. Vahed, 2020, Journal of Virology.

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

M. Leboyer, L. BenMohamed, M. Berk, 2011, Malaria Journal.

Long-Term Multiepitopic Cytotoxic-T-Lymphocyte Responses Induced in Chimpanzees by Combinations of Plasmodium falciparum Liver-Stage Peptides and Lipopeptides

L. BenMohamed, A. Thomas, P. Druilhe, 2004, Infection and Immunity.

SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions

L. BenMohamed, E. Bahraoui, R. Planès, 2022, Viruses.

Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant.

A. Nesburn, L. BenMohamed, Xiaoming Zhu, 2005, Vaccine.

High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56CD57PD-1

S. Prakash, Ruchi Srivastava, H. Vahed, 2022 .

Title Discovery of Potential Diagnostic and Vaccine Antigens in Herpes Simplex Virus 1 and 2 by Proteome-Wide Antibody Profiling Permalink

L. BenMohamed, G. Dasgupta, D. Molina, 2012 .

The Locus Encompassing the Latency-Associated Transcript of Herpes Simplex Virus Type 1 Interferes with and Delays Interferon Expression in Productively Infected Neuroblastoma Cells and Trigeminal Ganglia of Acutely Infected Mice

S. Wechsler, L. BenMohamed, Clinton Jones, 2005, Journal of Virology.

HIV-1 Envelope Glycoproteins Induce the Production of TNF-α and IL-10 in Human Monocytes by Activating Calcium Pathway

L. BenMohamed, E. Bahraoui, R. Planès, 2018, Scientific Reports.

HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes

L. BenMohamed, E. Bahraoui, R. Planès, 2016, Journal of Virology.

Title Targeting the Genital Tract Mucosa with a Lipopeptide / Recombinant Adenovirus Prime / Boost Vaccine Induces Potent and Long-Lasting CD 8 + T Cell Immunity Against Herpes : Importance of Myeloid Differentiation Factor

L. BenMohamed, X. Dervillez, A. Chentoufi, 2012 .

Herpes: Importance of MyD88 T Cell Immunity against + Long-Lasting CD8 Prime/Boost Vaccine Induces Potent and Lipopeptide/Recombinant Adenovirus Targeting the Genital Tract Mucosa with a

L. BenMohamed, X. Dervillez, A. Chentoufi, 2012 .

HIV-1 Tat Protein Induces PD-L1 (B7-H1) Expression on Dendritic Cells through Tumor Necrosis Factor Alpha- and Toll-Like Receptor 4-Mediated Mechanisms

L. BenMohamed, J. Izopet, E. Bahraoui, 2014, Journal of Virology.

Title HIV-1 Tat Protein Induces PD-L 1 ( B 7-H 1 ) Expression on Dendritic Cells through Tumor Necrosis Factor Alpha-and Toll-Like Receptor 4-Mediated Mechanisms Permalink

L. BenMohamed, J. Izopet, E. Bahraoui, 2014 .

The Role of LAT in Increased CD8 (cid:1) T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1 (cid:1)

G. Freeman, S. Wechsler, L. BenMohamed, 2011 .

Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants.

L. BenMohamed, D. Fidock, J. Meis, 1994, Journal of immunology.

Up-Regulation of Multiple CD8+ T Cell Exhaustion Pathways is Associated to Recurrent Ocular Herpes Simplex Virus Type 1 Infection

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2020 .

Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus

S. Wechsler, L. BenMohamed, Xianzhi Jiang, 2015, Current eye research.

Decreased reactivation of a herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation

Ruchi Srivastava, Arif A. Khan, S. Wechsler, 2015, Journal of NeuroVirology.

Future viral vectors for the delivery of asymptomatic herpes epitope-based immunotherapeutic vaccines.

L. BenMohamed, A. Chentoufi, 2010, Future virology.

Phenotypic and Functional Signatures of Herpes Simplex Virus–Specific Effector Memory CD73+CD45RAhighCCR7lowCD8+ TEMRA and CD73+CD45RAlowCCR7lowCD8+ TEM Cells Are Associated with Asymptomatic Ocular Herpes

Ruchi Srivastava, L. BenMohamed, S. Garg, 2018, The Journal of Immunology.

Asymptomatic memory CD8+ T cells

Ruchi Srivastava, Arif A. Khan, Patricia P. Lopes, 2014, Human vaccines & immunotherapeutics.

Targeting the Genital Tract Mucosa with a Lipopeptide/Recombinant Adenovirus Prime/Boost Vaccine Induces Potent and Long-Lasting CD8+ T Cell Immunity against Herpes: Importance of MyD88

L. BenMohamed, X. Dervillez, A. Chentoufi, 2012, The Journal of Immunology.

Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections

L. BenMohamed, A. Chentoufi, 2012, Clinical & developmental immunology.

Combinatorial Herpes Simplex Vaccine Strategies: From Bedside to Bench and Back

S. Prakash, Ruchi Srivastava, H. Vahed, 2022, Frontiers in Immunology.

Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2021, Frontiers in Immunology.

Healing of Primary and Recurrent Mouse Ocular Herpetic Disease Following Topical Ocular Treatment with an Engineered Fibroblast Growth Factor-1 (FGF-1) is Associated with Increased Frequency and Function of Corneal Anti-Inflammatory M2 Macrophages

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2020 .

Level of Herpes Simplex Virus Type 1 Latency Correlates with Severity of Corneal Scarring and Exhaustion of CD8+ T Cells in Trigeminal Ganglia of Latently Infected Mice

S. Wechsler, L. BenMohamed, C. Bresee, 2008, Journal of Virology.

Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine.

A. Nesburn, S. Wechsler, L. BenMohamed, 2012, Future virology.

Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown

A. Nesburn, L. BenMohamed, Elizabeth Kritzer, 2012, Clinical & developmental immunology.

Immunodominant “Asymptomatic” Herpes Simplex Virus 1 and 2 Protein Antigens Identified by Probing Whole-ORFome Microarrays with Serum Antibodies from Seropositive Asymptomatic versus Symptomatic Individuals

L. BenMohamed, G. Dasgupta, P. Felgner, 2012, Journal of Virology.

Asymptomatic Human CD4+ Cytotoxic T-Cell Epitopes Identified from Herpes Simplex Virus Glycoprotein B

L. BenMohamed, B. Maillère, G. Durand, 2008, Journal of Virology.

Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines.

A. Nesburn, S. Wechsler, L. BenMohamed, 2007, Investigative ophthalmology & visual science.

Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis

S. Wechsler, L. BenMohamed, J. Jester, 2016, Cornea.

Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpesvirus Infection

S. Prakash, Ruchi Srivastava, H. Vahed, 2022, Journal of virology.

Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpes Infection

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2021, bioRxiv.

CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease

Ruchi Srivastava, Arif A. Khan, L. BenMohamed, 2017, Journal of Virology.

Therapeutic Immunization with a Mixture of Herpes Simplex Virus 1 Glycoprotein D-Derived “Asymptomatic” Human CD8+ T-Cell Epitopes Decreases Spontaneous Ocular Shedding in Latently Infected HLA Transgenic Rabbits: Association with Low Frequency of Local PD-1+ TIM-3+ CD8+ Exhausted T Cells

Ruchi Srivastava, Arif A. Khan, N. Thai, 2015, Journal of Virology.

Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system.

A. Nesburn, S. Wechsler, L. BenMohamed, 2006, The ocular surface.

The Challenges and Opportunities for Development of a T-Cell Epitope-Based Herpes Simplex Vaccine

Christine Wang, L. BenMohamed, S. Chilukuri, 2014 .

Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.

A. Nesburn, L. BenMohamed, P. Van de Perre, 2012, Current trends in immunology.

The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8+ T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism

A. Nesburn, S. Wechsler, L. BenMohamed, 2011, Journal of Virology.

A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge

A. Nesburn, S. Wechsler, L. BenMohamed, 2009, Mucosal Immunology.

The Role of LAT in Increased CD8+ T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1

G. Freeman, S. Wechsler, L. BenMohamed, 2011, Journal of Virology.

The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Ruchi Srivastava, Arif A. Khan, A. Nesburn, 2016, Journal of Virology.

The wide utility of rabbits as models of human diseases

L. BenMohamed, G. Kaplan, G. McFadden, 2018, Experimental & Molecular Medicine.

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing

S. Wechsler, L. BenMohamed, Xianzhi Jiang, 2010, Journal of Virology.

Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect against Ocular Herpes Challenge

Ruchi Srivastava, Arif A. Khan, H. Vahed, 2018, Journal of Virology.

Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice

Ruchi Srivastava, Arif A. Khan, S. Wechsler, 2016, Current eye research.

Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?

L. BenMohamed, G. Dasgupta, 2011, Vaccine.

CD11c Controls Herpes Simplex Virus 1 Responses To Limit Virus Replication during Primary Infection

S. Wechsler, L. BenMohamed, C. Ballantyne, 2011, Journal of Virology.

Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.

A. Nesburn, L. BenMohamed, G. Dasgupta, 2011, Investigative ophthalmology & visual science.

A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8+ T Cell Epitope-Based Vaccines against Ocular Herpes

A. Nesburn, S. Wechsler, L. BenMohamed, 2010, The Journal of Immunology.

The role of a glycoprotein K (gK) CD8+ T-cell epitope of herpes simplex virus on virus replication and pathogenicity.

S. Wechsler, L. BenMohamed, H. Ghiasi, 2009, Investigative ophthalmology & visual science.

Upregulation of Multiple CD8+ T Cell Exhaustion Pathways Is Associated with Recurrent Ocular Herpes Simplex Virus Type 1 Infection

S. Prakash, Ruchi Srivastava, H. Vahed, 2020, The Journal of Immunology.

A Prime/Pull RR2/CXCL11 Therapeutic Vaccine that Bolsters the Number and Function of Dorsal Root Ganglia Tissue-Resident HSV-Specific CD8+ TRM Cells Protects Latently Infected Guinea Pigs from Recurrent Genital Herpes

S. Prakash, Ruchi Srivastava, H. Vahed, 2022, bioRxiv.

Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4+ and CD8+ TRM Cells Associated with Protection against Recurrent Genital Herpes

S. Prakash, Ruchi Srivastava, H. Vahed, 2019, Journal of Virology.

Bolstering the Number and Function of HSV-1–Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease

J. Sidney, A. Sette, Ruchi Srivastava, 2017, The Journal of Immunology.

Discovery of Potential Diagnostic and Vaccine Antigens in Herpes Simplex Virus 1 and 2 by Proteome-Wide Antibody Profiling

L. BenMohamed, G. Dasgupta, D. Molina, 2012, Journal of Virology.

Th-Cytotoxic T-Lymphocyte Chimeric Epitopes Extended by Nε-Palmitoyl Lysines Induce Herpes Simplex Virus Type 1-Specific Effector CD8+ Tc1 Responses and Protect against Ocular Infection

A. Nesburn, L. BenMohamed, Eric A. Berg, 2005, Journal of Virology.

Boosting immunity to small tumor-associated carbohydrates with bacteriophage qβ capsids.

L. BenMohamed, Marta Comellas-Aragonès, M. G. Finn, 2013, ACS chemical biology.

Protective immunity to genital herpes simplex virus type 1 and type 2 provided by self-adjuvanting lipopeptides that drive dendritic cell maturation and elicit a polarized Th1 immune response.

L. BenMohamed, Xiuli Zhang, I. Bettahi, 2006, Viral immunology.

Lipopeptide epitopes extended by an Nϵ‐palmitoyl‐lysine moiety increase uptake and maturation of dendritic cells through a Toll‐like receptor‐2 pathway and trigger a Th1‐dependent protective immunity

L. BenMohamed, B. Kaplan, H. Gras-masse, 2004, European journal of immunology.

Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8+ T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease

Ruchi Srivastava, H. Vahed, L. BenMohamed, 2018, Front. Immunol..

A herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation

S. Wechsler, L. BenMohamed, Xianzhi Jiang, 2015, Journal of NeuroVirology.

Lipopeptide immunization without adjuvant induces potent and long‐lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees

L. BenMohamed, A. Thomas, A. Tartar, 1997, European journal of immunology.

The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.

A. Nesburn, S. Wechsler, L. BenMohamed, 2012, Viral immunology.

The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) protects cells against cold-shock-induced apoptosis by maintaining phosphorylation of protein kinase B (AKT)

S. Wechsler, L. BenMohamed, Xianzhi Jiang, 2015, Journal of NeuroVirology.

Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer

A. Nesburn, L. BenMohamed, A. Chentoufi, 2009, Archivum Immunologiae et Therapiae Experimentalis.

The wide utility of rabbits as models of human diseases

L. BenMohamed, G. Kaplan, G. McFadden, 2018, Experimental & Molecular Medicine.

High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules.

L. BenMohamed, A. Thomas, J. Wubben, 2000, Vaccine.

Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy

Ruchi Srivastava, Arif A. Khan, L. BenMohamed, 2016, Inflammation.

Unique Type I Interferon, Expansion/Survival Cytokines, and JAK/STAT Gene Signatures of Multifunctional Herpes Simplex Virus-Specific Effector Memory CD8+ TEM Cells Are Associated with Asymptomatic Herpes in Humans

S. Prakash, Ruchi Srivastava, H. Vahed, 2018, Journal of Virology.

High Frequencies of PD-1+TIM3+TIGIT+CTLA4+ Functionally Exhausted SARS-CoV-2-Specific CD4+ and CD8+ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

S. Prakash, Ruchi Srivastava, H. Vahed, 2022, bioRxiv.

Lipopeptide vaccines--yesterday, today, and tomorrow.

A. Nesburn, S. Wechsler, L. BenMohamed, 2002, The Lancet. Infectious diseases.

Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D

L. BenMohamed, B. Maillère, F. Castelli, 2008, Clinical and Vaccine Immunology.

Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

S. Prakash, Ruchi Srivastava, L. BenMohamed, 2019, Journal of Virology.

Functional Foxp3+ CD4+ CD25(Bright+) “Natural” Regulatory T Cells Are Abundant in Rabbit Conjunctiva and Suppress Virus-Specific CD4+ and CD8+ Effector T Cells during Ocular Herpes Infection

A. Nesburn, S. Wechsler, L. BenMohamed, 2007, Journal of Virology.

Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines

S. Prakash, Ruchi Srivastava, A. Nesburn, 2021, The Journal of Immunology.

Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses

L. BenMohamed, D. Diamond, J. Primus, 2002, Immunology.

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

S. Buus, L. BenMohamed, F. Lemonnier, 2013, The Journal of Immunology.

Responses Versatile Preclinical Models of Human T Cell Hla-a*01:03, Hla-a*24:02, Hla-b*08:01

S. Buus, L. BenMohamed, F. Lemonnier, 2022 .

Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response.

L. BenMohamed, J. Longmate, D. Diamond, 2000, Human immunology.

CXCL17 Chemokine–Dependent Mobilization of CXCR8+CD8+ Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes

Ruchi Srivastava, Arif A. Khan, L. BenMohamed, 2018, The Journal of Immunology.

CXCL17 Chemokine-Dependent Mobilization of Memory CXCR8 + CD8 + T EM and T RM Cells in the Vaginal Mucosa is Associated with Protection Against Genital Herpes

Ruchi Srivastava, Arif A. Khan, L. BenMohamed, 2018 .

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model.

Ruchi Srivastava, Arif A. Khan, Jiawei Huang, 2015, Investigative ophthalmology & visual science.

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-Specific Effector and Memory CD8+ T Cells from Symptomatic and Asymptomatic Individuals with Ocular Herpes

Ruchi Srivastava, Arif A. Khan, D. Spencer, 2015, Journal of Virology.

Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry

E. Giralt, L. BenMohamed, O. Mzoughi, 2019, Bioscience reports.

A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T helper, and CTL epitopes.

L. BenMohamed, J. Meis, A. Thomas, 1996, Journal of immunology.

Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3

L. BenMohamed, A. Thomas, Joe D. Cohen, 2000, Nature Medicine.

Dysfunctional Senescent Herpes Simplex Virus Specific CD57+CD8+ T cells are Associated with Recurrent Symptomatic Herpes in Humans

Ruchi Srivastava, Arif A. Khan, H. Vahed, 2022, bioRxiv.

Herpes Simplex Virus Type 1 Human Asymptomatic CD 8 + T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a â��Humanizedâ�� HLA Transgenic Rabbit Model Permalink

Ruchi Srivastava, Arif A. Khan, Jiawei Huang, 2015 .

Immunity to Ocular and Genital Herpes Simplex Viruses Infections

L. BenMohamed, A. Ashkar, P. Van de Perre, 2012, Clinical & developmental immunology.

Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant

L. BenMohamed, Y. Belkaid, H. Gras-masse, 2002, European journal of immunology.

A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy

L. BenMohamed, V. Kimonis, A. Nalbandian, 2015, PloS one.

Author Correction: The wide utility of rabbits as models of human diseases

Jia Liu, Shan Lu, Neil Christensen, 2018, Experimental & Molecular Medicine.

Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity.

S. Wechsler, L. BenMohamed, Clinton Jones, 2008, Microbial pathogenesis.

Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy

Ruchi Srivastava, Arif A. Khan, L. BenMohamed, 2017, Inflammation.

Human Antibodies against Plasmodium falciparumLiver-Stage Antigen 3 Cross-React with Plasmodium yoelii Preerythrocytic-Stage Epitopes and Inhibit Sporozoite Invasion In Vitro and In Vivo

L. BenMohamed, G. Snounou, K. Brahimi, 2001, Infection and Immunity.

Increased neurovirulence and reactivation of the herpes simplex virus type 1 latency-associated transcript (LAT)-negative mutant dLAT2903 with a disrupted LAT miR-H2

S. Wechsler, L. BenMohamed, Xianzhi Jiang, 2016, Journal of NeuroVirology.

SARS-CoV-2 Envelope protein (E) binds and activates TLR2: A novel target for COVID-19 interventions

L. BenMohamed, E. Bahraoui, R. Planès, 2021, bioRxiv.

HIV-1 Infection Impairs HSV-Specific CD4+ and CD8+ T-Cell Response by Reducing Th1 Cytokines and CCR5 Ligand Secretion

L. BenMohamed, P. Van de Perre, N. Nagot, 2011, Journal of acquired immune deficiency syndromes.

O P I N I O N Open Access

L. BenMohamed, K. Brahimi, P. Druilhe, 2022 .

The challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccine.

Christine Wang, L. BenMohamed, S. Chilukuri, 2014, Vaccine.

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

L. BenMohamed, K. Brahimi, P. Druilhe, 2011, Malaria Journal.

High Frequencies of Antiviral Effector Memory TEM Cells and Memory B Cells Mobilized into Herpes Infected Vaginal Mucosa Associated With Protection Against Genital Herpes

S. Prakash, H. Vahed, L. BenMohamed, 2023, bioRxiv.

HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes

L. BenMohamed, E. Bahraoui, R. Planès, 2016, Journal of Virology.

J. Sidney, A. Sette, Arif A. Khan, 2013, The Journal of Immunology.

A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity.

Qureshi, L. BenMohamed, O. Renaudet, 2014, Angewandte Chemie.

Targeting the Genital Tract Mucosa with a Lipopeptide/Recombinant Adenovirus Prime/Boost Vaccine Induces Potent and Long-Lasting CD8+ T Cell Immunity against Herpes: Importance of MyD88

L. BenMohamed, X. Dervillez, A. Chentoufi, 2012, The Journal of Immunology.

A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8+ T Cell Epitope-Based Vaccines against Ocular Herpes

A. Nesburn, S. Wechsler, L. BenMohamed, 2010, The Journal of Immunology.

Towards a Self‐Adjuvanting Multivalent B and T cell Epitope Containing Synthetic Glycolipopeptide Cancer Vaccine

L. BenMohamed, G. Dasgupta, O. Renaudet, 2008, ChemMedChem.

Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44highCD62LlowCD8+ TEM Cells and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes

Ruchi Srivastava, A. Nesburn, L. BenMohamed, 2017 .

A Tribute to Professor Steven L. Wechsler (1948–2016): The Man and the Scientist

A. Nesburn, L. BenMohamed, 2017, Current Eye Research.

Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.

A. Nesburn, L. BenMohamed, G. Dasgupta, 2011, Investigative ophthalmology & visual science.

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

S. Buus, L. BenMohamed, F. Lemonnier, 2013, The Journal of Immunology.

Title Interferon-gamma , a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

L. BenMohamed, K. Brahimi, B. Perlaza, 2011 .

Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4+ and CD8+ T cells and protects against recurrent genital herpes.

S. Prakash, H. Vahed, L. BenMohamed, 2024, Journal of virology.

A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident memory CD4+ and CD8+ T cells and enhanced protection against COVID-19-like symptoms and death caused by SARS-CoV-2 infection

S. Prakash, H. Vahed, L. BenMohamed, 2023, Journal of Virology.

Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa.

S. Prakash, Ruchi Srivastava, H. Vahed, 2023, Journal of Immunology.

High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients

S. Prakash, Ruchi Srivastava, H. Vahed, 2024, Frontiers in Immunology.