T. Mulder-Krieger

发表

Identifying novel adenosine receptor ligands by simultaneous proteochemometric modeling of rat and human bioactivity data.

H. V. van Vlijmen, A. Bender, G. V. van Westen, 2012, Journal of medicinal chemistry.

2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.

A. IJzerman, T. Mulder-Krieger, H. de Vries, 2008, Journal of medicinal chemistry.

Allosteric modulation, thermodynamics and binding to wild‐type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine‐like agonist

A. IJzerman, T. Mulder-Krieger, L. Heitman, 2006, British journal of pharmacology.

Functional efficacy of adenosine A2A receptor agonists is positively correlated to their receptor residence time

A. IJzerman, T. Mulder-Krieger, D. Guo, 2012, British journal of pharmacology.

Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype

D. Boomsma, A. IJzerman, T. Mulder-Krieger, 2017, Biochemical pharmacology.

Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists.

A. IJzerman, T. Mulder-Krieger, D. Guo, 2015, European journal of medicinal chemistry.

The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptor.

Thea Mulder-Krieger, A. IJzerman, T. Mulder-Krieger, 2010, Biochemical pharmacology.

Putative role of the adenosine A3 receptor in the antiproliferative action of N6-(2-isopentenyl)adenosine

A. IJzerman, T. Mulder-Krieger, H. de Vries, 2011, Purinergic Signalling.

Identification of the alkaloids and anthraquinones in Cinchona ledgeriana callus cultures.

T. Mulder-Krieger, R. Verpoorte, A. de Water, 1982, Planta medica.

Anthraquinones in callus cultures of Cinchona ledgeriana

T. Mulder-Krieger, R. Verpoorte, A. Svendsen, 1984 .

Substructure‐Based Virtual Screening for Adenosine A2A Receptor Ligands

A. Bender, A. IJzerman, T. Mulder-Krieger, 2011, ChemMedChem.

2,6-disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists.

A. IJzerman, T. Mulder-Krieger, J. K. von Frijtag Drabbe Künzel, 2006, Journal of Medicinal Chemistry.

Dual-Point Competition Association Assay

A. IJzerman, T. Mulder-Krieger, D. Guo, 2013, Journal of biomolecular screening.

Synthesis and biological evaluation of 2-aminothiazoles and their amide derivatives on human adenosine receptors. Lack of effect of 2-aminothiazoles as allosteric enhancers.

A. IJzerman, T. Mulder-Krieger, A. Göblyös, 2005, Bioorganic & medicinal chemistry.

New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine.

A. IJzerman, T. Mulder-Krieger, J. K. von Frijtag Drabbe Künzel, 2004, Journal of medicinal chemistry.

A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptor.

A. IJzerman, T. Mulder-Krieger, J. K. von Frijtag Drabbe Künzel, 2005, Journal of medicinal chemistry.

A new generation of adenosine receptor antagonists: from di- to trisubstituted aminopyrimidines.

A. IJzerman, T. Mulder-Krieger, J. V. van Veldhoven, 2008, Bioorganic & medicinal chemistry.

Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists.

A. IJzerman, T. Mulder-Krieger, H. de Vries, 2017, European journal of medicinal chemistry.

Multi-Objective Evolutionary Design of Adenosine Receptor Ligands

Michael T. M. Emmerich, Adriaan P. IJzerman, Eelke van der Horst, 2012, J. Chem. Inf. Model..

2,4,6-trisubstituted pyrimidines as a new class of selective adenosine A1 receptor antagonists.

Thea Mulder-Krieger, Johannes Brussee, A. IJzerman, 2004, Journal of medicinal chemistry.

Production of essential oils and flavours in plant cell and tissue cultures. A review

A. Baerheim Svendsen, T. Mulder-Krieger, R. Verpoorte, 2004, Plant Cell, Tissue and Organ Culture.

2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.

A. IJzerman, T. Mulder-Krieger, J. K. von Frijtag Drabbe Künzel, 2007, Journal of medicinal chemistry.

Identification of Alkaloids and Anthraquinones in Cinchona pubescens Callus Cultures; the Effect of Plant growth Regulators and Light on the Alkaloid Content.

T. Mulder-Krieger, R. Verpoorte, A. Svendsen, 1984, Planta medica.

Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation

Woody Sherman, Adriaan P. IJzerman, Robert Abel, 2016, ACS omega.

High-performance liquid chromatography of Cinchona alkaloids : I. Normal-phase high-performance liquid chromatography

T. Mulder-Krieger, R. Verpoorte, J. Verzijl, 1983 .

Thin-layer chromatographic separation of cinchona alkaloids

T. Mulder-Krieger, R. Verpoorte, A. Svendsen, 1980 .

Plant Cell and Tissue Culture of Cinchona Species

T. Mulder-Krieger, R. Verpoorte, A. Svendsen, 1985 .

A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor.

Thea Mulder-Krieger, Johannes Brussee, A. IJzerman, 2009, Journal of medicinal chemistry.

Anthocyanins as Flower Pigments: Feasibilities for flower colour modification

T. Mulder-Krieger, R. Verpoorte, 1994 .

Anthocyanins as flower pigments

T. Mulder-Krieger, R. Verpoorte, 1993 .

Discovery and Kinetic Profiling of 7-Aryl-1,2,4-triazolo[4,3-a]pyridines: Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2.

A. IJzerman, T. Mulder-Krieger, L. Heitman, 2017, Journal of medicinal chemistry.

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ‐46281222

A. IJzerman, T. Mulder-Krieger, L. Heitman, 2016, British journal of pharmacology.

A New Class of Fluorinated A2A Adenosine Receptor Agonist with Application to Last‐Step Enzymatic [18F]Fluorination for PET Imaging

A. IJzerman, T. Mulder-Krieger, M. Zanda, 2017, Chembiochem : a European journal of chemical biology.

The13C-NMR spectrometry of cinchonamine and quinamine

T. Mulder-Krieger, R. Verpoorte, A. Svendsen, 1982, Pharmaceutisch Weekblad.

A new generation of adenosine receptor antagonists: from di- to trisubstituted aminopyrimidines.

A. IJzerman, T. Mulder-Krieger, J. V. van Veldhoven, 2008, Bioorganic & medicinal chemistry.