N. Thierry-Mieg

发表

Interaction networks: from protein functions to drug discovery. A review.

E. Chautard, N. Thierry-Mieg, S. Ricard-Blum, 2009, Pathologie-biologie.

Interaction networks as a tool to investigate the mechanisms of aging

E. Chautard, N. Thierry-Mieg, S. Ricard-Blum, 2010, Biogerontology.

FROM MODEL SYSTEMS A Model of Elegance

M. Vidal, N. Thierry-Mieg, H. Endoh, 2007 .

Shifted Transversal Design smart-pooling for high coverage interactome mapping.

M. Vidal, D. Hill, J. Rual, 2009, Genome research.

Proto-genes and de novo gene birth

César A. Hidalgo, A. Regev, M. Vidal, 2012, Nature.

Chapter 11:Strategies for Building Protein–Glycosaminoglycan Interaction Networks Combining SPRi, SPR, and BLI

Sylvain D. Vallet, N. Thierry-Mieg, S. Ricard-Blum, 2017 .

Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. elegans

T. Moore, M. Vidal, D. Hill, 2001, Nature Genetics.

Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse.

N. Thierry-Mieg, S. Brouillet, P. Ray, 2018, American journal of human genetics.

interactome mapping Shifted Transversal Design smart-pooling for high coverage

M. Vidal, D. Hill, Xiaofeng Xin, 2009 .

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

N. Thierry-Mieg, B. Conne, P. Jouk, 2018, Nature Communications.

T Cell–Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Micet

N. Thierry-Mieg, P. Arner, J. Zierath, 2009, Circulation research.

A protein – protein interaction map of the Caenorhabditis elegans 26 S proteasome

M. Vidal, D. Thierry-Mieg, A. J. Walhout, 2013 .

T Cell–Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Mice

N. Thierry-Mieg, P. Arner, J. Zierath, 2009 .

A recurrent ZP1 variant is responsible for oocyte maturation defect with degenerated oocytes in infertile females

N. Thierry-Mieg, P. Ray, Zine-Eddine Kherraf, 2022, Clinical genetics.

INSIGHTS FROM MODEL SYSTEMS A Model of Elegance

M. Vidal, N. Thierry-Mieg, H. Endoh, 1998 .

Protein interaction mapping in C. elegans using proteins involved in vulval development.

M. Vidal, J. Hartley, G. Temple, 2000, Science.

Smart-pooling et interactomes

N. Thierry-Mieg, 2013 .

Whole exome sequencing of men with multiple morphological abnormalities of the sperm flagella reveals novel homozygous QRICH2 mutations

N. Thierry-Mieg, P. Ray, H. Gourabi, 2019, Clinical genetics.

Whole exome sequencing of men with multiple morphological abnormalities of the sperm flagella reveals novel homozygous QRICH 2 mutations

N. Thierry-Mieg, P. Ray, H. Gourabi, 2019 .

A model of elegance.

M. Vidal, N. Thierry-Mieg, H. Endoh, 1998, American journal of human genetics.

Chapter 8 Mapping Interactomes with High Coverage and Effi ciency Using the Shifted Transversal Design

Xiaofeng Xin, Charles Boone, N. Thierry-Mieg, 2011 .

Whole-exome sequencing improves the diagnosis and care of men with non-obstructive azoospermia.

N. Thierry-Mieg, P. Ray, L. Raymond, 2022, American journal of human genetics.

SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes

Thomas Karaouzene, Nicolas Thierry-Mieg, Serge Nef, 2017, EMBO molecular medicine.

Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice.

N. Thierry-Mieg, B. Conne, P. Ray, 2019, American journal of human genetics.

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

N. Thierry-Mieg, B. Conne, P. Ray, 2018, EMBO Molecular Medicine.

Identification and Characterization of the Most Common Genetic Variant Responsible for Acephalic Spermatozoa Syndrome in Men Originating from North Africa

N. Thierry-Mieg, P. Ray, Zine-Eddine Kherraf, 2021, International journal of molecular sciences.

A Homozygous Ancestral SVA-Insertion-Mediated Deletion in WDR66 Induces Multiple Morphological Abnormalities of the Sperm Flagellum and Male Infertility.

M. Blum, N. Thierry-Mieg, P. Ray, 2018, American journal of human genetics.

CFAP70 mutations lead to male infertility due to severe astheno-teratozoospermia. A case report.

N. Thierry-Mieg, S. Brouillet, P. Ray, 2019, Human reproduction.

Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.

N. Thierry-Mieg, D. Grunwald, P. Jouk, 2014, American journal of human genetics.

Fine Characterisation of a Recombination Hotspot at the DPY19L2 Locus and Resolution of the Paradoxical Excess of Duplications over Deletions in the General Population

N. Thierry-Mieg, P. Jouk, F. Abada, 2013, PLoS genetics.

MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities

Sylvie Ricard-Blum, Guillaume Launay, Nicolas Thierry-Mieg, 2014, Nucleic Acids Res..

Genetic analyses of a large cohort of infertile patients with globozoospermia, DPY19L2 still the main actor, GGN confirmed as a guest player

N. Thierry-Mieg, L. Pasquier, Flore Mietton, 2020, Human Genetics.

Genetic analyses of a large cohort of infertile patients with globozoospermia, DPY19L2 still the main actor, GGN confirmed as a guest player

N. Thierry-Mieg, L. Pasquier, Flore Mietton, 2020, Human genetics.

A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome

M. Vidal, D. Thierry-Mieg, A. J. Walhout, 2001, EMBO reports.

The [PSI+] prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12

N. Thierry-Mieg, M. Ott, J. Stewart, 2021, bioRxiv.

Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation

R. Sachidanandam, N. Thierry-Mieg, R. Pillai, 2017, The EMBO journal.

Whole-exome sequencing identifies mutations in FSIP2 as a recurrent cause of multiple morphological abnormalities of the sperm flagella

N. Thierry-Mieg, P. Ray, Zine-Eddine Kherraf, 2018, Human reproduction.

The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility

N. Thierry-Mieg, P. Santulli, P. Ray, 2021, Clinical genetics.

Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility

N. Thierry-Mieg, P. Ray, Y. Fichou, 2020, Journal of Medical Genetics.

Novel axonemal protein ZMYND12 is required for flagellum function and male fertility

N. Thierry-Mieg, P. Ray, J. Dupuy, 2023 .

Lack of CCDC 146 , a ubiquitous centriole and microtubule-associated protein , 2 leads to non-syndromic male infertility in human and mouse 3 4 5

N. Thierry-Mieg, S. Geimer, P. Ray, 2023 .

Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions

L. Salwínski, I. Jurisica, R. Lovering, 2018, BMC Bioinformatics.

MatrixDB: integration of new data with a focus on glycosaminoglycan interactions

Sylvie Ricard-Blum, Madeline Deniaud, Nicolas Thierry-Mieg, 2018, Nucleic Acids Res..

Defect in the nuclear pore membrane glycoprotein 210-like gene is associated with extreme uncondensed sperm nuclear chromatin and male infertility: a case report.

N. Thierry-Mieg, P. Ray, A. Loundou, 2020, Human reproduction.

New Mutations in DNHD1 Cause Multiple Morphological Abnormalities of the Sperm Flagella

N. Thierry-Mieg, P. Ray, Zine-Eddine Kherraf, 2023, International journal of molecular sciences.

Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B

N. Thierry-Mieg, P. Ray, S. Nef, 2021, Cells.

A missense mutation in IFT74, encoding for an essential component for intraflagellar transport of Tubulin, causes asthenozoospermia and male infertility without clinical signs of Bardet–Biedl syndrome

N. Thierry-Mieg, P. Ray, Zine-Eddine Kherraf, 2021, Human Genetics.

InterDB, a Prediction-Oriented Protein Interaction Database for C. elegans

Laurent Trilling, Nicolas Thierry-Mieg, N. Thierry-Mieg, 2000, JOBIM.

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

N. Thierry-Mieg, B. Conne, P. Jouk, 2018, Nature Communications.

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

N. Thierry-Mieg, B. Conne, P. Jouk, 2018, Nature Communications.

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP.

N. Thierry-Mieg, P. Ray, S. Savinov, 2016, Human molecular genetics.

New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size

Nicolas Thierry-Mieg, Laure Sambourg, Laure Sambourg, 2010, BMC Bioinformatics.

MatrixDB, a database focused on extracellular protein–protein and protein–carbohydrate interactions

Sylvie Ricard-Blum, Nicolas Thierry-Mieg, Emilie Chautard, 2009, Bioinform..

A new pooling strategy for high-throughput screening: the Shifted Transversal Design

Nicolas Thierry-Mieg, N. Thierry-Mieg, 2006, BMC Bioinformatics.

MatrixDB, the extracellular matrix interaction database

Sylvie Ricard-Blum, Nicolas Thierry-Mieg, Emilie Chautard, 2010, Nucleic Acids Res..

Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function

N. Thierry-Mieg, P. Ray, J. Dupuy, 2023, bioRxiv.

Bi-allelic truncating variants in CFAP206 cause male infertility in human and mouse

N. Thierry-Mieg, Kuokuo Li, F. Tao, 2021, Human Genetics.

Whole-exome sequencing identi fi es mutations in FSIP 2 as a recurrent cause of multiple morphological abnormalities of the sperm fl agella

N. Thierry-Mieg, P. Ray, C. Coutton, 2018 .

Absence of CFAP 69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse

N. Thierry-Mieg, S. Brouillet, P. Ray, 2018 .

Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans

N. Thierry-Mieg, P. Ray, Caroline Cazin, 2023, iScience.

A novel pooling design for protein-protein interaction mapping

N. Thierry-Mieg, Laurent Trilling, Jean-Louis Roch, 2003 .

Genetic causes of macrozoospermia and proposal for an optimized genetic diagnosis strategy based on sperm parameters.

N. Thierry-Mieg, P. Ray, E. Bieth, 2023, Journal of genetics and genomics = Yi chuan xue bao.

Interaction networks as a tool to investigate the mechanisms of aging

N. Thierry-Mieg, S. Ricard-Blum, Emilie Chautard, 2010, Biogerontology.

Shifted Transversal Design smart-pooling for high coverage interactome mapping.

M. Vidal, Xiaofeng Xin, Charles Boone, 2009, Genome research.

T Cell–Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Micet

N. Thierry-Mieg, P. Arner, J. Zierath, 2009, Circulation research.

Biological screens from linear codes: theory and tools

Atri Rudra, Hung Q. Ngo, Anna C. Gilbert, 2015, bioRxiv.