C. Giordano

发表

The Role of PPARγ Ligands in Breast Cancer: From Basic Research to Clinical Studies

Giuseppina Augimeri, C. Giordano, L. Gelsomino, 2020, Cancers.

Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1‐mediated p53 activation

C. Giordano, L. Gelsomino, I. Barone, 2012, Journal of cellular physiology.

Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation

C. Giordano, I. Barone, S. Catalano, 2009, Journal of cellular physiology.

In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

C. Giordano, M. Rossi, P. Ferruzzi, 2012, International journal of cancer.

Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination

C. Giordano, S. Catalano, S. Andò, 2012, Breast Cancer Research and Treatment.

Monitoring the effects of iodine prophylaxis in the adult population of southern Italy with deficient and sufficient iodine intake levels: a cross-sectional, epidemiological study

Massimiliano Gallo, C. Giordano, I. Barone, 2017, The British journal of nutrition.

Leptin Modulates Exosome Biogenesis in Breast Cancer Cells: An Additional Mechanism in Cell-to-Cell Communication

Giuseppina Augimeri, C. Giordano, L. Gelsomino, 2019, Journal of clinical medicine.

Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells—identification of a novel androgen response element

C. Giordano, S. Catalano, S. Andò, 2010, Nucleic acids research.

Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells

C. Giordano, A. Scarpa, M. Rossi, 2010, Bioscience reports.

Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages

S. Fuqua, C. Giordano, L. Gelsomino, 2020, Biomolecules.

Estrogens and PTP1B function in a novel pathway to regulate aromatase enzymatic activity in breast cancer cells.

C. Giordano, I. Barone, S. Catalano, 2012, Endocrinology.

Identification of novel 2-(1H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth and motility.

C. Giordano, I. Barone, S. Catalano, 2016, Future medicinal chemistry.

Adherence to the Mediterranean diet pattern among university staff: a cross-sectional web-based epidemiological study in Southern Italy

C. Giordano, I. Barone, S. Catalano, 2019, International journal of food sciences and nutrition.

Impact of Mediterranean Diet Food Choices and Physical Activity on Serum Metabolic Profile in Healthy Adolescents: Findings from the DIMENU Project

Giuseppina Augimeri, C. Giordano, I. Barone, 2022, Nutrients.

Phosphodiesterase type 5 and cancers: progress and challenges

C. Giordano, I. Barone, S. Catalano, 2017, Oncotarget.

The Biology of Exosomes in Breast Cancer Progression: Dissemination, Immune Evasion and Metastatic Colonization

C. Giordano, L. Gelsomino, I. Barone, 2020, Cancers.

Rapid Estradiol/ER (cid:1) Signaling Enhances Aromatase Enzymatic Activity in Breast Cancer Cells

C. Giordano, I. Barone, S. Catalano, 2009 .

A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo

C. Giordano, L. Gelsomino, I. Barone, 2015, Journal of cellular and molecular medicine.

Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells.

C. Giordano, S. Catalano, S. Andò, 2004, The Journal of biological chemistry.

Leptin, obesity and breast cancer: progress to understanding the molecular connections.

C. Giordano, I. Barone, S. Catalano, 2016, Current opinion in pharmacology.

Leptin Receptor as a Potential Target to Inhibit Human Testicular Seminoma Growth.

C. Giordano, L. Gelsomino, I. Barone, 2019, The American journal of pathology.

Farnesoid X Receptor, through the Binding with Steroidogenic Factor 1-responsive Element, Inhibits Aromatase Expression in Tumor Leydig Cells*

C. Giordano, S. Catalano, S. Andò, 2009, The Journal of Biological Chemistry.

N-Eicosapentaenoyl Dopamine, A Conjugate of Dopamine and Eicosapentaenoic Acid (EPA), Exerts Anti-inflammatory Properties in Mouse and Human Macrophages

Giuseppina Augimeri, C. Giordano, P. Plastina, 2019, Nutrients.

Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter

S. Fuqua, C. Giordano, I. Barone, 2012, Breast Cancer Research and Treatment.

Triiodothyronine decreases the activity of the proximal promoter (PII) of the aromatase gene in the mouse Sertoli cell line, TM4.

C. Giordano, S. Catalano, S. Andò, 2003, Molecular endocrinology.

Aromatase expression in prepuberal Sertoli cells: effect of thyroid hormone

C. Giordano, S. Andò, M. Lanzino, 2001, Molecular and Cellular Endocrinology.

Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines.

C. Giordano, L. Gelsomino, I. Barone, 2018, Cancer letters.

Fas ligand expression in TM4 sertoli cells is enhanced by estradiol “in situ” production

C. Giordano, I. Barone, S. Catalano, 2007, Journal of cellular physiology.

Proteomic Profiling of Extracellular Vesicles Released by Leptin-Treated Breast Cancer Cells: A Potential Role in Cancer Metabolism

C. Giordano, L. Gelsomino, I. Barone, 2022, International journal of molecular sciences.

Endemic Goiter and Iodine Prophylaxis in Calabria, a Region of Southern Italy: Past and Present

C. Giordano, I. Barone, S. Catalano, 2019, Nutrients.

Estrogen receptor signaling

C. Giordano, I. Barone, S. Andò, 2008 .

Identi ﬁ cation and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells

C. Giordano, A. Caricasole, Boping Liu, 2022 .

Androgens inhibit aromatase expression through DAX-1: insights into the molecular link between hormone balance and Leydig cancer development.

C. Giordano, I. Barone, S. Catalano, 2015, Endocrinology.

Epigallocatechin gallate inhibits growth and epithelial‐to‐mesenchymal transition in human thyroid carcinoma cell lines

C. Giordano, S. Andò, D. Bonofiglio, 2013, Journal of cellular physiology.

n–3 Polyunsaturated Fatty Acid Amides: New Avenues in the Prevention and Treatment of Breast Cancer

C. Giordano, P. Plastina, I. Barone, 2020, International journal of molecular sciences.

Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative and apoptotic effects in human breast cancer cells.

C. Giordano, P. Plastina, I. Barone, 2012, Journal of ethnopharmacology.

Natural and Synthetic PPARγ Ligands in Tumor Microenvironment: A New Potential Strategy against Breast Cancer

Giuseppina Augimeri, C. Giordano, L. Gelsomino, 2020, International journal of molecular sciences.

Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy

B. Győrffy, C. Giordano, I. Barone, 2015, Clinical Cancer Research.

Nutraceuticals in the Mediterranean Diet: Potential Avenues for Breast Cancer Treatment

Giuseppina Augimeri, C. Giordano, I. Barone, 2021, Nutrients.

DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

C. Giordano, I. Barone, S. Catalano, 2013, Cell Death and Disease.

Omega-3 DHA and EPA Conjugates Trigger Autophagy Through PPARγ Activation in Human Breast Cancer Cells

C. Giordano, S. Catalano, S. Andò, 2016 .

Omega-3 DHA- and EPA-dopamine conjugates induce PPARγ-dependent breast cancer cell death through autophagy and apoptosis.

C. Giordano, P. Plastina, I. Barone, 2015, Biochimica et biophysica acta.

Leptin and Notch Signaling Cooperate in Sustaining Glioblastoma Multiforme Progression

C. Giordano, L. Gelsomino, I. Barone, 2020, Biomolecules.

FoxO3a Inhibits Tamoxifen-Resistant Breast Cancer Progression by Inducing Integrin α5 Expression

C. Giordano, I. Barone, D. Bonofiglio, 2022, Cancers.

FoxO3a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer

C. Giordano, D. Bonofiglio, F. Sotgia, 2019, Cancers.

Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line*

C. Giordano, S. Catalano, S. Andò, 2003, Journal of Biological Chemistry.

Omega‐3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF‐7 breast cancer cells

C. Giordano, P. Plastina, I. Barone, 2013, Journal of cellular physiology.

Mechanisms of divergent effects of activated peroxisome proliferator-activated receptor-γ on mitochondrial citrate carrier expression in 3T3-L1 fibroblasts and mature adipocytes.

C. Giordano, I. Barone, S. Catalano, 2013, Biochimica et biophysica acta.

Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells.

C. Giordano, L. Gelsomino, I. Barone, 2012, Cancer research.

The weight of obesity in breast cancer progression and metastasis: clinical and molecular perspectives.

C. Giordano, I. Barone, S. Catalano, 2020, Seminars in cancer biology.

Obesity, Leptin and Breast Cancer: Epidemiological Evidence and Proposed Mechanisms

C. Giordano, L. Gelsomino, I. Barone, 2019, Cancers.

The Emerging Role of Extracellular Vesicles in Endocrine Resistant Breast Cancer

C. Giordano, L. Gelsomino, I. Barone, 2021, Cancers.

Evidence for Enhanced Exosome Production in Aromatase Inhibitor-Resistant Breast Cancer Cells

B. Győrffy, Giuseppina Augimeri, C. Giordano, 2020, International journal of molecular sciences.

Activation of Farnesoid X Receptor impairs the tumor-promoting function of breast cancer-associated fibroblasts.

B. Győrffy, C. Giordano, L. Gelsomino, 2018, Cancer letters.

Phosphodiesterase 5 (PDE5) Is Highly Expressed in Cancer-Associated Fibroblasts and Enhances Breast Tumor Progression

B. Győrffy, Giuseppina Augimeri, C. Giordano, 2019, Cancers.

Obesity and endocrine therapy resistance in breast cancer: Mechanistic insights and perspectives

C. Giordano, L. Gelsomino, I. Barone, 2021, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Leptin Induces, via ERK1/ERK2 Signal, Functional Activation of Estrogen Receptor α in MCF-7 Cells*

C. Giordano, S. Catalano, S. Andò, 2004, Journal of Biological Chemistry.

Chemical Therapeutics Identi fi cation and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells

C. Giordano, A. Caricasole, F. Ng, 2013 .

Impact of Vigorous-Intensity Physical Activity on Body Composition Parameters, Lipid Profile Markers, and Irisin Levels in Adolescents: A Cross-Sectional Study

C. Giordano, I. Barone, S. Catalano, 2020, Nutrients.

Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression

C. Giordano, I. Barone, S. Catalano, 2016, Oncotarget.

Effects of tri-iodothyronine on alternative splicing events in the coding region of cytochrome P450 aromatase in immature rat Sertoli cells.

C. Giordano, S. Andò, M. Lanzino, 2001, The Journal of endocrinology.

Rapid estradiol/ERalpha signaling enhances aromatase enzymatic activity in breast cancer cells.

C. Giordano, I. Barone, S. Catalano, 2009, Molecular endocrinology.

Glucocorticoid Receptor as a Potential Target to Decrease Aromatase Expression and Inhibit Leydig Tumor Growth.

C. Giordano, L. Gelsomino, I. Barone, 2016, The American journal of pathology.

Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity

B. Győrffy, C. Giordano, I. Barone, 2015, Oncotarget.

The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression

C. Giordano, I. Barone, S. Catalano, 2014, Front. Oncol..

Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression.

C. Giordano, I. Barone, S. Catalano, 2007, Cancer research.

Natural Products as Promising Antitumoral Agents in Breast Cancer: Mechanisms of Action and Molecular Targets.

C. Giordano, S. Andò, D. Bonofiglio, 2016, Mini reviews in medicinal chemistry.

Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPARγ Ligands as a Potential Target in Breast Cancer

Giuseppina Augimeri, C. Giordano, L. Gelsomino, 2020, Cells.

Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth

S. Fuqua, C. Giordano, I. Barone, 2014, Breast Cancer Research and Treatment.

LPL, FNDC5 and PPARγ gene polymorphisms related to body composition parameters and lipid metabolic profile in adolescents from Southern Italy

C. Giordano, I. Barone, S. Catalano, 2022, Journal of translational medicine.

Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression

Giuseppina Augimeri, C. Giordano, L. Gelsomino, 2020, Cancers.

Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor α and its phosphorylation at serine 305

S. Fuqua, C. Giordano, I. Barone, 2009, Breast Cancer Research and Treatment.

Leptin increases HER2 protein levels through a STAT3‐mediated up‐regulation of Hsp90 in breast cancer cells

C. Giordano, I. Barone, S. Catalano, 2013, Molecular oncology.

Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells

B. Győrffy, C. Giordano, L. Gelsomino, 2021, Cancers.

Adipocyte-derived extracellular vesicles promote breast cancer cell malignancy through HIF-1α activity.

C. Giordano, L. Gelsomino, I. Barone, 2021, Cancer letters.

Phosphodiesterase Type 5 as a Candidate Therapeutic Target in Cancers

C. Giordano, I. Barone, S. Catalano, 2015, Current Pathobiology Reports.

Benzofuran-2-acetic ester derivatives induce apoptosis in breast cancer cells by upregulating p21Cip/WAF1 gene expression in p53-independent manner.

C. Giordano, I. Barone, S. Catalano, 2017, DNA repair.

Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.

S. Fuqua, C. Giordano, I. Barone, 2009, Cancer research.

Inhibition of leydig tumor growth by farnesoid X receptor activation: The in vitro and in vivo basis for a novel therapeutic strategy

C. Giordano, I. Barone, S. Catalano, 2013, International journal of cancer.

Nutrition Education Program and Physical Activity Improve the Adherence to the Mediterranean Diet: Impact on Inflammatory Biomarker Levels in Healthy Adolescents From the DIMENU Longitudinal Study

C. Giordano, I. Barone, S. Catalano, 2021, Frontiers in Nutrition.

Analysis of circulating extracellular vesicle derived microRNAs in breast cancer patients with obesity: a potential role for Let-7a

B. Győrffy, C. Giordano, L. Gelsomino, 2023, Journal of Translational Medicine.

FoxO 3 a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer

C. Giordano, D. Bonofiglio, F. Sotgia, 2019 .

Activated FXR Inhibits Leptin Signaling and Counteracts Tumor-promoting Activities of Cancer-Associated Fibroblasts in Breast Malignancy

C. Giordano, L. Gelsomino, I. Barone, 2016, Scientific Reports.

Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression

S. Fuqua, C. Giordano, L. Gelsomino, 2011, Oncogene.

Self-Perceived Physical Activity and Adherence to the Mediterranean Diet in Healthy Adolescents during COVID-19: Findings from the DIMENU Pilot Study

C. Giordano, D. Bonofiglio, D. Sisci, 2021, Healthcare.

Potential Antioxidant and Anti-Inflammatory Properties of Serum from Healthy Adolescents with Optimal Mediterranean Diet Adherence: Findings from DIMENU Cross-Sectional Study

Giuseppina Augimeri, C. Giordano, I. Barone, 2021, Antioxidants.

The Omega-3 Docosahexaenoyl Ethanolamide Reduces CCL5 Secretion in Triple Negative Breast Cancer Cells Affecting Tumor Progression and Macrophage Recruitment

Giuseppina Augimeri, C. Giordano, I. Barone, 2023, Cancers.

Leptin: A Heavyweight Player in Obesity-Related Cancers

C. Giordano, L. Gelsomino, I. Barone, 2023, Biomolecules.

Serum from Adolescents with High Polyphenol Intake Exhibits Improved Lipid Profile and Prevents Lipid Accumulation in HepG2 Human Liver Cells

Giuseppina Augimeri, C. Giordano, I. Barone, 2023, Oxidative medicine and cellular longevity.

CEBP-β and PLK1 as Potential Mediators of the Breast Cancer/Obesity Crosstalk: In Vitro and In Silico Analyses

C. Giordano, L. Gelsomino, I. Barone, 2023, Nutrients.

A Palladium-Catalyzed Carbonylation Approach to Eight-Membered Lactam Derivatives with Antitumor Activity.

C. Giordano, I. Barone, S. Catalano, 2016, Chemistry.