J. Glass

R. Conwit, J. Licht, P. Andersen, 2012, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

ALSUntangled No. 36: Accilion

R. Conwit, J. Licht, P. Andersen, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

Gary L. Pattee, Samuel P. Dickson, Stephen A. Goutman, 2020, The New England journal of medicine.

50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis

Robert H. Brown, S. Purcell, J. Glass, 2008, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Stem cell transplantation for amyotrophic lateral sclerosis

J. Glass, C. Svendsen, R. Baloh, 2018, Current opinion in neurology.

TDP-43 cytoplasmic inclusion formation is disrupted in C9orf72-associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration

D. Gutman, M. Gearing, J. Glass, 2019, Brain communications.

Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in ALS patients and their relatives

P. Andersen, A. Birve, J. Glass, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Human neural stem cell transplantation in ALS: initial results from a phase I trial

J. Glass, C. Giorgi, C. Cisari, 2015, Journal of Translational Medicine.

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy

Alan J. Thomas, G. Schellenberg, G. Deuschl, 2022, Movement disorders : official journal of the Movement Disorder Society.

Amyotrophic Lateral Sclerosis Genetic Access Program

J. Glass, C. Zaleski, J. Roggenbuck, 2021, Neurology: Genetics.

GEN-01 The ALS GAP program: paving the way for genetic characterization of ALS in the clinic

J. Glass, J. Roggenbuck, Tara Lincoln, 2019 .

Title: Mutations in ANXA11 cause familial and sporadic amyotrophic lateral sclerosis

Robert H. Brown, M. Weale, F. Baas, 2016 .

A novel ALS SOD1 C6S mutation with implications for aggregation related toxicity and genetic counseling

P. Andersen, A. Birve, J. Glass, 2011, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain of function

J. Glass, R. Parlato, Jochen H Weishaupt, 2022, bioRxiv.

Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

T. Montine, A. Levey, N. Seyfried, 2014, Brain pathology.

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines

Andrea D Matlock, J. Krakauer, K. Sachs, 2020, Nature Neuroscience.

Control of astrocytosis by interleukin-1 and transforming growth factor-β1 in human brain

J. Glass, W. Tyor, J. J. Jefferson, 1993, Brain Research.

Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS

M. Gearing, J. Glass, J. Rothstein, 2012, Proceedings of the National Academy of Sciences.

Chronic demyelinating polyneuropathy associated with eosinophilia-myalgia syndrome.

J. Glass, J. Griffin, D. Cornblath, 1992, Journal of neurology, neurosurgery, and psychiatry.

Conduction block in diabetic neuropathy

J. Glass, G. Ronnett, D. Cornblath, 1991, Muscle & nerve.

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36

Chadwick M. Hales, L. Petrucelli, D. Dickson, 2020, Neuron.

An open label study of a novel immunosuppression intervention for the treatment of amyotrophic lateral sclerosis

Robert H. Brown, D. Schoenfeld, J. Glass, 2018, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

Sonja W. Scholz, Hannah A. Pliner, Janel O. Johnson, 2021, JAMA neurology.

Amyotrophic lateral sclerosis care and research in the United States during the COVID‐19 pandemic: Challenges and opportunities

S. Paganoni, J. Glass, J. Rothstein, 2020, Muscle & nerve.

The Effect of SMN Gene Dosage on ALS Risk and Disease Severity

M. Eberle, A. Al-Chalabi, P. Andersen, 2021, Annals of neurology.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Timothy A. Miller, Sonja W. Scholz, Jennifer E. Phillips-Cremins, 2020, Neuron.

Hypercaloric enteral nutrition in Amyotrophic Lateral Sclerosis: a randomized double-blind placebo-controlled trial

J. Lou, J. Glass, H. Mitsumoto, 2014 .

Title Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis : a randomised , double-blind , placebo-controlled phase 2 trial

J. Lou, J. Glass, M. Cudkowicz, 2014 .

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

Claire L. Simpson, R. Ophoff, H. Horvitz, 2009, Proceedings of the National Academy of Sciences.

Long‐term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS

Parag G. Patil, Stephen A. Goutman, P. Patil, 2018, Annals of clinical and translational neurology.

Analysis of graft survival in a trial of stem cell transplant in ALS

D. Brat, M. Gearing, J. Glass, 2014, Annals of clinical and translational neurology.

Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I trial, cervical microinjection, and final surgical safety outcomes.

J. Glass, E. Feldman, Jonathan P. Riley, 2014, Neurosurgery.

Nerve conduction studies in diabetic neuropathy

F. Walker, J. Glass, E. Mellits, 1995, Neurology.

Long‐term survival of participants in the CENTAUR trial of sodium phenylbutyrate‐taurursodiol in amyotrophic lateral sclerosis

Gary L. Pattee, Samuel P. Dickson, Stephen A. Goutman, 2020, Muscle & nerve.

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

J. Glass, J. Khan, M. Polak, 2004, Experimental Neurology.

Stathmin-2: adding another piece to the puzzle of TDP-43 proteinopathies and neurodegeneration.

J. Glass, 2020, The Journal of clinical investigation.

Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal

J. Glass, L. Hayes, S. Asress, 2019, Experimental Neurology.

Protecting the nerve terminals

J. Glass, 2018, eLife.

Pathophysiology of nerve and root disorders

G. Mckhann, J. Glass, W. Mcdonald, 2002 .

AIDS and the Nervous System

J. Glass, S. Wesselingh, 2003 .

Title : Phosphorylated neurofilament heavy chain : a biomarker of survival for C 9 ORF 72-associated amyotrophic lateral sclerosis

Leonard, William T. Hu, J. Trojanowski, 2017 .

A Unique Mutation in Connexin32 Associated with Severe, Early Onset CMTX in a Heterozygous Female

K. Fischbeck, J. Glass, S. Scherer, 1999, Annals of the New York Academy of Sciences.

Longitudinal biomarkers in amyotrophic lateral sclerosis

Robert H. Brown, K. Scearce-Levie, J. Glass, 2020, Annals of clinical and translational neurology.

Neurologic prognosis of cytomegalovirus polyradiculomyelopathy in AIDS

J. Glass, J. McArthur, B. Cohen, 1993, Neurology.

Chronic inflammatory demyelinating polyneuropathy and paraproteinemic neuropathies

J. Glass, D. Cornblath, 1994, Current opinion in neurology.

A. J. Kumar, V. Mathews, J. Glass, 1992, AJNR. American journal of neuroradiology.

The Heritability of Amyotrophic Lateral Sclerosis in a Clinically Ascertained United States Research Registry

D. Cutler, J. Glass, T. Wingo, 2011, PloS one.

Calcium‐Mediated Degeneration of the Axonal Cytoskeleton in the Ola Mouse

J. Glass, J. Griffin, B. Schryer, 1994, Journal of neurochemistry.

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease

A. Levey, N. Seyfried, M. Gearing, 2019, Science Advances.

Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.

Timothy A. Miller, A. Pestronk, P. Andersen, 2020, The New England journal of medicine.

Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data

Kristen A. Severson, Andrea D Matlock, J. Krakauer, 2022, Nature Computational Science.

Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review.

Timothy A. Miller, J. Glass, J. Rothstein, 2022, JAMA neurology.

Association of Epstein-Barr virus with primary central nervous system lymphoma in AIDS.

J. Glass, J. McArthur, R. Ambinder, 1992, AIDS research and human retroviruses.

Poliomyelitis due to West Nile virus.

M. Rich, J. Glass, O. Samuels, 2002, The New England journal of medicine.

A 61-Year-Old Woman With Progressive Weakness and Rash

J. Glass, J. Greene, Eric R. Anderson, 2012, The Neurohospitalist.

Re: The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol 2021;80(3):210-9.

J. Glass, 2021, Journal of neuropathology and experimental neurology.

Generation of spectrin breakdown products in peripheral nerves by addition of M‐calpain

J. Glass, D. Culver, M. Castejón, 1999, Muscle & nerve.

The dysarthria—clumsy hand syndrome: A distinct clinical entity related to pontine infarction

A. Levey, J. Glass, J. Rothstein, 1990, Annals of neurology.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene in and for Therapeutic

Timothy A. Miller, Denis C. Bauer, Shankaracharya, 2018 .

Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.

C. Hampton, J. Glass, F. Fernández, 2010, Journal of medicinal chemistry.

Mutations in the tail domain of the neurofilament heavy chain gene increase the risk of amyotrophic lateral sclerosis

A. Al-Chalabi, J. Glass, J. Landers, 2022, medRxiv.

The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

Timothy A. Miller, A. Al-Chalabi, C. Shaw, 2022, Nature Communications.

A Potential Role for Interferon-α in the Pathogenesis of HIV-Associated Dementia

J. Glass, S. Wesselingh, J. McArthur, 1995, Brain, Behavior, and Immunity.

A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia.

J. Glass, S. Wesselingh, J. McArthur, 1995, Brain, behavior, and immunity.

Inter‐ and intra‐examiner reliability of nerve conduction measurements in normal subjects

J. Glass, E. Mellits, G. Ronnett, 1991, Annals of neurology.

ALSUntangled: Introducing The Table of Evidence

R. Conwit, J. Licht, P. Andersen, 2015, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI)

Emily C. Hector, N. Seyfried, J. Glass, 2022, Metabolites.

ALSUntangled #67: rituximab

Gary L. Pattee, J. Glass, M. Benatar, 2022, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Cytomegalovirus encephalitis in acquired immunodeficiency syndrome (AIDS)

V. Mathews, J. Glass, J. McArthur, 1994, Neurology.

Molecular dynamics analysis of Superoxide Dismutase 1 mutations suggests decoupling between mechanisms underlying ALS onset and progression

Timothy A. Miller, R. Dobson, A. Al-Chalabi, 2022, bioRxiv.

Clinically meaningful change: evaluation of the Rasch-built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS) and the ALSFRS-R

J. Glass, Christina N. Fournier, Virginia James, 2022, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Late-stage CTE pathology in a retired soccer player with dementia

Chadwick M. Hales, M. Gearing, J. Glass, 2014, Neurology.

Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data

Ross P. Byrne, Ashley R. Jones, A. Al-Chalabi, 2022, Frontiers in Cellular Neuroscience.

Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP

Chadwick M. Hales, William T. Hu, J. Trojanowski, 2013, Neurology.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, C. Carlson, K. Lunetta, 2014, JAMA neurology.

Toward more efficient clinical trials for amyotrophic lateral sclerosis

B. Levin, D. Schoenfeld, J. Glass, 2010, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Exome sequencing to identify de novo mutations in sporadic ALS trios

G. Crabtree, O. King, J. Glass, 2013, Nature Neuroscience.

Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.

Timothy A. Miller, A. Chiò, J. Glass, 2022, The New England journal of medicine.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination

Jonathan D. Glass, J. Glass, J. Griffin, 1992, Journal of Neuroimmunology.

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

Chadwick M. Hales, Daniela C. Zarnescu, L. Petrucelli, 2017, Alzheimer's & Dementia.

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.

G. Comi, S. Corti, V. Moskvina, 2014, Human molecular genetics.

A genome-wide association meta-analysis identifies a novel locus at 17 q 11 . 2 associated with sporadic amyotrophic lateral sclerosis

Aleksey, Davide, Moskvina, 2014 .

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

Annelot M. Dekker, Robert H. Brown, F. Baas, 2016, Nature Genetics.

Brain-derived HIV-1 tat sequences from AIDS patients with dementia show increased molecular heterogeneity.

J. Glass, J. McArthur, J. McArthur, 1998, Journal of neurovirology.

Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis

Ross P. Byrne, Ashley R. Jones, A. Al-Chalabi, 2022, NPJ genomic medicine.

Paraoxonase gene mutations in amyotrophic lateral sclerosis

Robert H. Brown, D. A. Bosco, J. Glass, 2010, Annals of neurology.

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

Annelot M. Dekker, Raymond D. Schellevis, N. Wray, 2017, European Journal of Human Genetics.

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Robert H. Brown, R. Petersen, B. Boeve, 2016, Nature Communications.

Mutations in the Profilin 1 Gene Cause Familial Amyotrophic Lateral Sclerosis

S. C. Chafe, D. Goldstein, Robert H. Brown, 2012, Nature.

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis

Robert H. Brown, D. A. Bosco, C. Shaw, 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

Denis C. Bauer, Annelot M. Dekker, Ashley R. Jones, 2017, Nature Communications.

Cellular toxicity of mutant SOD1 protein is linked to an easily soluble, non-aggregated form in vitro

J. Glass, Yingjie Li, Terrell Brotherton, 2013, Neurobiology of Disease.

Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia

J. Glass, S. Wesselingh, J. McArthur, 1995, Annals of neurology.

Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood‐brain barrier

T. Crawford, J. Glass, B. Trapp, 1993, Annals of neurology.

Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards.

A. Levey, N. Seyfried, M. Gearing, 2012, Journal of proteome research.

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.

Madhav Thambisetty, Marla Gearing, Vivek Swarup, 2017, Cell systems.

Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry

J. Glass, S. Wesselingh, J. McArthur, 1997, Journal of Neuroimmunology.

Ftld-tdp to Tau Ratio Is a Biomarker for 181 Reduced Csf P-tau

Chadwick M. Hales, William T. Hu, J. Trojanowski, 2022 .

Dural scrofula

J. Glass, J. Troncoso, P. S. Becker, 1989, Neurology.

Genome-wide association study and functional validation implicates JADE1 in tauopathy

M. Mesulam, T. Montine, P. Hof, 2021, bioRxiv.

Interleukin-6 protects against paclitaxel, cisplatin and vincristine-induced neuropathies without impairing chemotherapeutic activity

J. Glass, N. Callizot, P. Vitte, 2008, Cancer Chemotherapy and Pharmacology.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences

B. Chesebro, J. Glass, J. McArthur, 1994, Journal of virology.

Gut microbiome differences between amyotrophic lateral sclerosis patients and spouse controls

K. Nelson, J. Glass, M. Torralba, 2021, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Potential Role of the Gut Microbiome in ALS: A Systematic Review

J. Glass, V. Hertzberg, M. Tansey, 2018, Biological research for nursing.

Very early activation of m-calpain in peripheral nerve during Wallerian degeneration

A. Levey, J. Glass, N. Nash, 2002, Journal of the Neurological Sciences.

Human immunodeficiency virus and the brain.

J. Glass, R. Johnson, Jonathan Glass, 1996, Annual review of neuroscience.

Localization of HIV‐1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

J. Glass, S. Wesselingh, J. McArthur, 1996, Annals of neurology.

Cytokine dysregulation in HIV-associated neurological disease.

J. Glass, S. Wesselingh, J. McArthur, 1994, Advances in neuroimmunology.

Cytokine expression in the brain during the acquired immunodeficiency syndrome

J. Glass, J. McArthur, D. Griffin, 1992, Annals of neurology.

Single nucleus multiome analysis of the prefrontal cortex from C9orf72 ALS/FTD patients illuminates pathways affected during disease progression

M. Gearing, J. Glass, V. Corces, 2023 .

Clinicopathologic correlations of HIV‐1‐associated vacuolar myelopathy

J. Glass, J. McArthur, G. J. Pan, 1994, Neurology.

Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dememtia

J. Glass, S. Wesselingh, D. Griffin, 1993, Annals of neurology.

ALS Untangled No. 17: “When ALS Is Lyme”

R. Conwit, J. Licht, P. Andersen, 2012, Amyotrophic Lateral Sclerosis.

Generalized tetanus despite prior vaccination and a protective level of anti-tetanus antibodies.

J. Glass, D. Livorsi, M. Eaton, 2010, The American journal of the medical sciences.

Loss of dopamine phenotype among midbrain neurons in Lesch–Nyhan disease

M. Gearing, J. Glass, H. Jinnah, 2014, Annals of neurology.

Translational stem cell therapy for amyotrophic lateral sclerosis

Eva L. Feldman, Jonathan D. Glass, J. Glass, 2012, Nature Reviews Neurology.

New drugs for ALS: How do we get there?

J. Glass, 2012, Experimental Neurology.

Preventing familial amyotrophic lateral sclerosis: Is a clinical trial feasible?

J. Glass, M. Benatar, S. Kaplan, 2006, Journal of the Neurological Sciences.

Systemic pharmacokinetics and cerebrospinal fluid uptake of intravenous ceftriaxone in patients with amyotrophic lateral sclerosis

A. Pestronk, D. Schoenfeld, D. Greenblatt, 2014, Journal of clinical pharmacology.

Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis

James D. Berry, Jeremy M. Shefner, Jeffrey Rosenfeld, 2013, PloS one.

Antecedent Disease Is Less Prevalent in Amyotrophic Lateral Sclerosis

Cassie S. Mitchell, Jonathan D. Glass, J. Glass, 2015, Neurodegenerative Diseases.

Autosomal dominant distal spinal muscular atrophy in four generations

T. Gilliam, J. Glass, D. Cornblath, 1995, Neurology.

Poly(Gp) Proteins Are A Useful Pharmacodynamic Marker For C9Orf72-Associated Amyotrophic Lateral Sclerosis

William T. Hu, Robert H. Brown, L. Petrucelli, 2017 .

Behavior Matters—Cognitive Predictors of Survival in Amyotrophic Lateral Sclerosis

William T. Hu, A. Levey, M. Grossman, 2013, PloS one.

Phosphorylated neurofilament heavy subunit (pNF-H) in peripheral blood and CSF as a potential prognostic biomarker in amyotrophic lateral sclerosis

Gerry Shaw, Jonathan D Glass, J. Glass, 2012, Journal of Neurology, Neurosurgery & Psychiatry.

Mitochondrial abnormalities in dermatomyositis: characteristic pattern of neuropathology

O. Bagasra, J. Glass, Mohammed Alhatou, 2004, Journal of Molecular Histology.

A common haplotype within the PON1 promoter region is associated with sporadic ALS

Robert H. Brown, A. Al-Chalabi, C. Shaw, 2008, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

The gut microbiome and neuroinflammation in amyotrophic lateral sclerosis? Emerging clinical evidence

J. Glass, V. Hertzberg, M. Tansey, 2020, Neurobiology of Disease.

Inter‐ and intraexaminer reliability of nerve conduction measurements in patients with diabetic neuropathy

J. Glass, E. Mellits, D. Cornblath, 1994, Neurology.

Axonal Degeneration in Motor Neuron Disease

J. Glass, L. Fischer, 2007, Neurodegenerative Diseases.

Wlds mice are resistant to paclitaxel (taxol) neuropathy

J. Glass, M. Wang, A. Davis, 2002, Annals of neurology.

SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.

J. Glass, G. Manfredi, J. Hansen, 2011, Brain : a journal of neurology.

Wilson's disease. Development of neurological disease after beginning penicillamine therapy.

M. Delong, J. Glass, S. Reich, 1990, Archives of neurology.

Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration

A. Levey, N. Seyfried, C. Heilman, 2011, Molecular Neurodegeneration.

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

D. G. Clark, C. Carlson, K. Lunetta, 2015, JAMA neurology.

The role of calcitonin gene‐related peptide in cutaneous immunosuppression induced by repeated subinflammatory ultraviolet irradiation exposure

J. Glass, P. Wolf, A. Solomon, 2004, Experimental dermatology.

Identifying Patterns of ALS Progression from Sparse Longitudinal Data

Kristen A. Severson, K. Sachs, E. Fraenkel, 2021, medRxiv.

Axonal degeneration and disorders of the axonal cytoskeleton

E. B. George, J. Glass, S. Hsieh, 2009 .

Alpha blocking: absence in visuobehavioral deprivation

J. Glass, 1977, Science.

ALSUntangled No. 16: Cannabis

R. Conwit, J. Licht, P. Andersen, 2012, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

CSF beta-amyloid 1–42 – what are we measuring in Alzheimer's disease?

William T. Hu, J. Trojanowski, A. Levey, 2014, Annals of clinical and translational neurology.

Defining SOD1 ALS natural history to guide therapeutic clinical trial design

A. Pestronk, J. Glass, T. Siddique, 2016, Journal of Neurology, Neurosurgery & Psychiatry.

Microglia in HIV‐associated neurological diseases

J. Glass, S. Wesselingh, 2001, Microscopy research and technique.

Distinct HIV-1 env sequences are associated with neurotropism and neurovirulence.

B. Chesebro, J. Glass, J. McArthur, 1995, Current topics in microbiology and immunology.

Cytokine expression of macrophages in HIV‐1‐associated vacuolar myelopathy

J. Glass, J. McArthur, D. Griffin, 1993, Neurology.

Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS

J. Glass, J. Connor, M. Cudkowicz, 2012, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model.

J. Glass, S. Wesselingh, R. Fain, 2010, Current HIV research.

Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon

E. B. George, J. Glass, J. Griffin, 1993, Journal of neurocytology.

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.

M. Mesulam, P. Hof, J. Trojanowski, 2020, Journal of neuropathology and experimental neurology.

Neuronal pattern correlates with the severity of human immunodeficiency virus-associated dementia complex. Usefulness of spatial pattern analysis in clinicopathological studies.

P. Lantos, J. Glass, G. Dunn, 1996, The American journal of pathology.

Pathogenesis of Axonal Degeneration: Parallels Between Wallerian Degeneration and Vincristine Neuropathy

Yuehua Wu, J. Glass, D. Culver, 2000, Journal of neuropathology and experimental neurology.

Theme 2 Genetics and genomics

J. Glass, J. Roggenbuck, Tara Lincoln, 2019, Amyotrophic lateral sclerosis & frontotemporal degeneration.

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

L. Petrucelli, Y. Zhang, N. Seyfried, 2018, Nature Neuroscience.

Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis

J. Glass, Terrell Brotherton, Lindsey R. Fischer-Hayes, 2013, Experimental Neurology.

SOD 1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod 1 knockout mouse

J. Glass, G. Manfredi, J. Hansen, 2010 .

A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS

G. Kerchner, J. Galanter, J. Glass, 2022, Annals of clinical and translational neurology.

ATXN2 intermediate expansions in amyotrophic lateral sclerosis.

J. Glass, J. Landers, B. Traynor, 2022, Brain : a journal of neurology.

Head injury does not alter disease progression or neuropathologic outcomes in ALS

M. Gearing, J. Glass, M. Klein, 2015, Neurology.

Interpretable deep learning of myelin histopathology in age-related cognitive impairment

Thomas J. Fuchs, M. Mesulam, T. Montine, 2022, bioRxiv.

The Gene for Slow Wallerian Degeneration (Wlds ) Is Also Protective against Vincristine Neuropathy

Yuehua Wu, J. Glass, D. Culver, 2001, Neurobiology of Disease.

Modeling the course of amyotrophic lateral sclerosis

J. Glass, Christina Fournier, Jonathan D Glass, 2015, Nature Biotechnology.

ALSUntangled No. 26: Lunasin

R. Conwit, J. Licht, P. Andersen, 2014, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival

Ashley R. Jones, G. Breen, A. Al-Chalabi, 2022, Frontiers in Cellular Neuroscience.

NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration

J. Glass, G. Magni, B. Beirowski, 2007, Cell Death and Differentiation.

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.

Sandra D'Alfonso, Adriano Chiò, Aleksey Shatunov, 2016, JAMA neurology.

The WldS protein protects against axonal degeneration: A model of gene therapy for peripheral neuropathy

M. Rich, J. Glass, M. Wang, 2001, Annals of neurology.

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Chadwick M. Hales, J. Glass, H. Mitsumoto, 2017, Molecular Neurodegeneration.

Neuronal density in the superior frontal and temporal gyri does not correlate with the degree of human immunodeficiency virus-associated dementia

P. Lantos, J. Glass, J. McArthur, 1994, Acta Neuropathologica.

Looking backward to move forward: a meta-analysis of stem cell therapy in amyotrophic lateral sclerosis

J. Glass, L. Mazzini, R. Sánchez-Pernaute, 2021, npj Regenerative Medicine.

Variable progression of HIV‐associated dementia

O. Selnes, J. Glass, F. Bouwman, 1998, Neurology.

The APCs of neuroprotection.

J. Glass, C. Esmon, 2009, The Journal of clinical investigation.

Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C.

J. Glass, S. Asress, L. Chin, 2013, Human molecular genetics.

Localization of HIV-1 DNA and tumor necrosis factor-alpha mRNA in human brain using polymerase chain reaction in situ hybridization and immunocytochemistry.

J. Glass, S. Wesselingh, 2000, Methods in molecular biology.

Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome

B. Chesebro, J. Glass, Richard T. Johnson, 1996, Annals of neurology.

Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion

G. Gibson, M. Hegde, J. Glass, 2019, Muscle and Nerve.

Selecting promising ALS therapies in clinical trials.

J. Glass, M. Benatar, M. Polak, 2007, Neurology.

Seeking a measure of clinically meaningful change in ALS

R. Goetz, J. Rabkin, J. Glass, 2014, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Treadmill Gait Analysis Does Not Detect Motor Deficits in Animal Models of Parkinson's Disease or Amyotrophic Lateral Sclerosis

G. Miller, J. Glass, S. Asress, 2008, Journal of motor behavior.

Class I and II histone deacetylase expression is not altered in human amyotrophic lateral sclerosis: Neuropathological and positron emission tomography molecular neuroimaging evidence

Nicole R. Zürcher, J. Glass, J. Berry, 2019, Muscle & nerve.

Predicting disease progression in amyotrophic lateral sclerosis

Neta Zach, Albert A. Taylor, Mike Keymer, 2016, Annals of clinical and translational neurology.

Development and validation of a machine-learning ALS survival model lacking vital capacity (VC-Free) for use in clinical trials during the COVID-19 pandemic

S. Paganoni, J. Glass, J. Berry, 2021, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Unsupervised machine-learning identifies clinically distinct subtypes of ALS that reflect different genetic architectures and biological mechanisms

Ahmad Al Khleifat, A. Al-Chalabi, P. Andersen, 2023, medRxiv.

Looking backward to move forward: a meta-analysis of stem cell therapy in amyotrophic lateral sclerosis

J. Glass, L. Mazzini, R. Sánchez-Pernaute, 2021, npj Regenerative Medicine.

ALSUntangled #64: butyrates

S. Paganoni, J. Glass, M. Bromberg, 2022, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Implementing Motor Unit Number Index (MUNIX) in a large clinical trial: Real world experience from 27 centres

J. Glass, T. Ferguson, M. Bromberg, 2018, Clinical Neurophysiology.

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

M. Nalls, N. Staff, L. Petrucelli, 2023, bioRxiv.

CAMTA 1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

Aleksey, C. Lewis, S. Newhouse, 2018 .

Association of a Locus in the CAMTA 1 GeneWith Survival in PatientsWith Sporadic Amyotrophic Lateral Sclerosis

Adriano Chiò, Philip Van Damme, Aleksey Shatunov, 2016 .

New VAPB deletion variant and exclusion of VAPB mutations in familial ALS

A. Al-Chalabi, C. Shaw, J. Glass, 2008, Neurology.

Genome-wide association study of autopsy-confirmed Multiple System Atrophy identifies common variants near ZIC1 and ZIC4

Alan J. Thomas, A. Peters, G. Schellenberg, 2021, medRxiv.

The spatial relationship between neurons and astrocytes in HIV-associated dementia

S. Rabe-Hesketh, S. Landau, J. Glass, 2013, Journal of NeuroVirology.

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

Ryan L. Collins, Sonja W. Scholz, Toshiko Tanaka, 2023, Cell genomics.

ALSUntangled No. 34: GM604.

Gary L. Pattee, R. Conwit, J. Licht, 2016, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Validation of machine learning models to detect amyloid pathologies across institutions

Michael J. Keiser, D. Gutman, M. Gearing, 2020, Acta Neuropathologica Communications.

ALSUntangled No. 29: MitoQ

R. Conwit, J. Licht, P. Andersen, 2015, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Increased frequency of the tumor necrosis factor‐α‐308 a allele in adults with human immunodeficiency virus dementia

J. Glass, J. McArthur, M. Quasney, 2001, Annals of neurology.

Development and Validation of the Rasch-Built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS).

J. Glass, V. Hertzberg, R. Bedlack, 2019, JAMA neurology.

Peripheral nerve disorders in HIV infection. Similarities and contrasts with CNS disorders.

J. Glass, S. Wesselingh, J. McArthur, 1994, Research publications - Association for Research in Nervous and Mental Disease.

Estimating the effect of PEG in ALS patients using observational data subject to censoring by death and missing outcomes

Brent A. Johnson, J. Glass, Q. Long, 2019, 1905.02062.

Adoptive transfer of IL-10+ regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model

J. Glass, A. Pennati, J. Galipeau, 2018, Cellular & Molecular Immunology.

Dusty: an assistive mobile manipulator that retrieves dropped objects for people with motor impairments

Chih-Hung King, Tiffany L. Chen, Zhengqin Fan, 2011, Disability and rehabilitation. Assistive technology.

Hand it over or set it down: A user study of object delivery with an assistive mobile manipulator

Tiffany L. Chen, Advait Jain, Charles C. Kemp, 2009, RO-MAN 2009 - The 18th IEEE International Symposium on Robot and Human Interactive Communication.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Margaret A. Pericak-Vance, John X. Morris, Jonathan L. Haines, 2012, Neurology.

A multielectrode microcompartment culture platform for studying signal transduction in the nervous system.

A. B. Frazier, Jonathan D Glass, J. Glass, 2006, Lab on a chip.

Genetic and phenotype analyses of primary lateral sclerosis datasets from international cohorts

Ahmad Al Khleifat, A. Al-Chalabi, C. Shaw, 2023, medRxiv.

Differential diagnosis of acute flaccid paralysis and its role in poliomyelitis surveillance.

J. Glass, R. Sutter, A. Marx, 2000, Epidemiologic reviews.

Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration

A. Levey, N. Seyfried, C. Heilman, 2022 .

Peripheral Monitoring of Immune Response to Intraspinal Stem Cell Therapy

J. Glass, A. Kirk, N. Boulis, 2014 .

Rapid diagnosis of cytomegalovirus polyradiculitis in a patient with acquired immunodeficiency syndrome

J. Glass, Y. Erozan, 1993, Annals of Neurology.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, Jason J. Corneveaux, C. Carlson, 2014, JAMA neurology.

TDP-43 cytoplasmic inclusion formation is disrupted in C9orf72-associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration

Chadwick M. Hales, D. Gutman, M. Gearing, 2019, Brain communications.

Gliosis in human brain: relationship to size but not other properties of astrocytes

J. Glass, W. Tyor, L. Vitković, 1993, Brain Research.

Spatiotemporal localization of injury potentials in DRG neurons during vincristine-induced axonal degeneration

Surendra K. Ravula, Maxine A. McClain, Jonathan D. Glass, 2007, Neuroscience Letters.

Stereological analysis of cerebral atrophy in human immunodeficiency virus-associated dementia.

J. Glass, J. McArthur, H. Fedor, 1996, Journal of neuropathology and experimental neurology.

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.

C. Carlson, K. Lunetta, D. Geschwind, 2015, JAMA neurology.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

John X. Morris, Jason J. Corneveaux, Asha A. Nair, 2012, Neurology.

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.

Chadwick M. Hales, D. Geschwind, A. Levey, 2017, Cell systems.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, Jason J. Corneveaux, C. Carlson, 2014, JAMA neurology.

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

Annelot M. Dekker, Ashley R. Jones, F. Baas, 2016, Nature Genetics.

ALSUntangled No. 36: Accilion

Gary L. Pattee, R. Conwit, J. Licht, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

C. Geula, M. Mesulam, J. Grafman, 2019, Acta Neuropathologica.

The Project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public

Naomi R. Wray, Mamede de Carvalho, Blaz Koritnik, 2018, bioRxiv.

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

Timothy A. Miller, L. Petrucelli, J. Trojanowski, 2017, Science Translational Medicine.

Genetic variability in sporadic amyotrophic lateral sclerosis

A. Al-Chalabi, P. Andersen, J. Glass, 2023, Brain : a journal of neurology.

Mutations in the Profilin 1 Gene Cause Familial Amyotrophic Lateral Sclerosis

S. C. Chafe, D. Goldstein, M. Moore, 2012, Nature.

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Annelot M. Dekker, Raymond D. Schellevis, Ashley R. Jones, 2016, Nature Genetics.

ALS‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function

J. Glass, R. Parlato, Jochen H Weishaupt, 2022, EMBO reports.

The ultimate question: why do axons degenerate? A tribute to the work and mentorship of John W. Griffin, MD

J. Glass, 2012, Journal of the peripheral nervous system : JPNS.

Axonal neurofilaments are resistant to calpain-mediated degradation in the WLD(S) mouse.

J. Glass, B. Bernier, D. Culver, 1999, Neuroreport.

Cloning of M‐calpain 80 kD subunit from the axonal degeneration‐resistant WLDs mouse mutant

A. Levey, J. Glass, I. Dry, 1998, Journal of neuroscience research.

Peripheral neuropathy in HIV infection: Lessons for the CNS

J. Glass, S. Wesselingh, J. McArthur, 1992, Journal of Neurological Sciences.

Non‐toxic melanoma therapy by a novel tubulin‐binding agent

J. Glass, Jun Zhou, P. Rida, 2010, International journal of cancer.

Alzheimer research forum live discussion: mice on trial? Issues in the design of drug studies.

J. Glass, S. Perrin, B. Barres, 2009, Journal of Alzheimer's disease : JAD.

Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

Chadwick M. Hales, T. Montine, A. Levey, 2014, Brain pathology.

Implementing Motor Unit Number Index (MUNIX) in a large clinical trial: Real world experience from 27 centres

J. Glass, T. Ferguson, M. Bromberg, 2018, Clinical Neurophysiology.