N. Shimizu

发表

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region.

S. Minoshima, A. Shiohama, Takashi Sasaki, 2003, Biochemical and biophysical research communications.

Detection of Her2/neu, c-MYC and ZNF217 gene amplification during breast cancer progression using fluorescence in situ hybridization.

N. Shimizu, S. Asakawa, M. Shimada, 2005, Oncology reports.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Kanako O. Koyanagi, Michael A. Thomas, H. Mewes, 2004, PLoS Biology.

Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome

N. Shimizu, Y. Hiraoka, T. Haraguchi, 2003, BMC Cell Biology.

A novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21

N. Shimizu, J. Kudoh, S. Asakawa, 2013, Transgenic Research.

A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.

N. Shimizu, J. Kudoh, A. Yamaki, 2004, Biochemical and biophysical research communications.

Genomic Bacterial Artificial Chromosome Library of the Japanese Flounder Paralichthys olivaceus

N. Shimizu, S. Asakawa, I. Hirono, 2000, Marine Biotechnology.

Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations.

N. Shimizu, T. Hara, J. Kudoh, 2002, Clinical immunology.

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

S. Minoshima, N. Shimizu, N. Hattori, 1998, Nature.

Medaka genomics: a bridge between mutant phenotype and gene function

Y. Kohara, N. Shimizu, H. Takeda, 2004, Mechanisms of Development.

Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921))

Ronald W. Davis, J. V. Moran, V. J. Pollara, 2001 .

The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.

N. Kenmochi, K. Kawasaki, S. Minoshima, 2002, Genome research.

Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells

N. Shimizu, T. Iwatsubo, N. Hattori, 2005 .

Corrigendum to “Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells” [Biochem. Biophys. Res. Commun. 332 (2005) 233–240]

N. Shimizu, T. Iwatsubo, N. Hattori, 2005 .

Construction of BAC libraries derived from the ascidian Ciona intestinalis.

N. Shimizu, N. Satoh, S. Asakawa, 2002, Genes & genetic systems.

The medaka draft genome and insights into vertebrate genome evolution

Fumiko Ohta, Sumio Sugano, Shinichi Morishita, 2007, Nature.

Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T-cell tolerance.

L. Peltonen, N. Shimizu, J. Kudoh, 2011, The Journal of investigative dermatology.

The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor

N. Shimizu, S. Asakawa, M. Kondo, 2001, Current Biology.

Dual promoter expression system with insulator ensures a stringent tissue-specific regulation of two reporter genes in the transgenic fish

N. Shimizu, A. Shimizu, 2012, Transgenic Research.

Correction: Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Kanako O. Koyanagi, Michael A. Thomas, Gopal R. Gopinath, 2004, PLoS biology.

The myocilin (MYOC) gene expression in the human trabecular meshwork

S. Minoshima, S. Noda, N. Shimizu, 2000 .

Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

Matthias Platzer, Markus Schilhabel, Adam Frankish, 2004, BMC Genomics.

Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.

Takashi Sasaki, N. Shimizu, Nobuyoshi Shimizu, 2007, Gene.

Identification of eight members of the Argonaute family in the human genome.

Shinsei Minoshima, S. Minoshima, A. Shiohama, 2003, Genomics.

A unified nomenclature for the superfamily of TRP cation channels.

Craig Montell, Michael J Caterina, Stefan Heller, 2002, Molecular cell.

Single–minded and Down syndrome?

S. Antonarakis, S. Minoshima, N. Shimizu, 1995, Nature Genetics.

High-Level Expression of Golsyn/Syntabulin in Glandular Epithelium and its Role in the Secretory Process

N. Shimizu, Fumiaki Ito, E. Funakoshi, 2010 .

Autoimmune Regulator (AIRE) Gene Is Expressed in Human Activated CD4+ T‐Cells and Regulated by Mitogen‐Activated Protein Kinase Pathway

N. Shimizu, S. Yamasaki, J. Kudoh, 2006, Microbiology and immunology.

AIRE Functions As an E3 Ubiquitin Ligase

N. Shimizu, K. Nakayama, J. Kudoh, 2004, The Journal of experimental medicine.

MutationView/KMcancerDB: A database for cancer gene mutations

S. Minoshima, N. Shimizu, M. Ohtsubo, 2007, Cancer science.

Parkin Mutations (Park 2)

S. Minoshima, N. Shimizu, N. Hattori, 2003 .

Identification of the 58-kDa phosphoprotein associated with motility initiation of hamster spermatozoa.

N. Shimizu, S. Yamaoka, M. Okuno, 2003, Journal of biochemistry.

Targeted gene delivery using humanized single‐chain antibody with negatively charged oligopeptide tail

N. Shimizu, A. Takayanagi, Masataka Suzuki, 2004, Cancer science.

Polycystic Kidney Disease in the Medaka (Oryzias latipes) pc Mutant Caused by a Mutation in the Gli-Similar3 (glis3) Gene

Y. Kohara, N. Shimizu, S. Asakawa, 2009, PloS one.

CancerProView: a graphical image database of cancer-related genes and proteins.

N. Shimizu, S. Mitsuyama, 2012, Genomics.

Detection of Epidermal Growth Factor Receptor Gene Amplification in Human Squamous Cell Carcinomas Using Fluorescence in situ Hybridization

S. Minoshima, N. Shimizu, J. Ishitoya, 1994, Japanese journal of cancer research : Gann.

A physical map of the human genome

D. Haussler, B. Trask, R. Wilson, 2001, Nature.

Identification of 66 kDa phosphoprotein associated with motility initiation of hamster spermatozoa

N. Shimizu, M. Okuno, H. Ohtake, 2004, Reproductive medicine and biology.

The KM‐parkin‐DB: A Sub‐set MutationView Database Specialized for PARK2 (PARKIN) Variants

S. Minoshima, N. Shimizu, S. Mitsuyama, 2015, Human mutation.

Two patients with atypical interstitial deletions of 8p23.1: Mapping of phenotypical traits

N. Shimizu, R. Matsuoka, N. Matsumoto, 2008, American journal of medical genetics. Part A.

Construction of a BAC library for the red sea bream Pagrus major

N. Shimizu, S. Asakawa, I. Hirono, 2002 .

Analysis of Transposable-Element Clustering Patterns in Magnaporthe Grisea Genome Using BAC Library

N. Shimizu, M. Masuya, S. Asakawa, 2000 .

Autosomal recessive juvenile parkinsonism: A key to understanding nigral degeneration in sporadic Parkinson's disease

N. Shimizu, N. Hattori, S. Asakawa, 2000, Neuropathology : official journal of the Japanese Society of Neuropathology.

FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium

N. Shimizu, S. Asakawa, H. Takeda, 2010, Development.

FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium

N. Shimizu, S. Asakawa, H. Takeda, 2010, Journal of Cell Science.

The KK-Periome database for transcripts of periodontal ligament development.

Takashi Sasaki, N. Shimizu, T. Yoneda, 2009, Journal of experimental zoology. Part B, Molecular and developmental evolution.

Databases and ontologies MEPD : a resource for medaka gene expression patterns

M. Westerfield, H. Himmelbauer, Takashi Sasaki, 2005 .

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Shinsei Minoshima, Nobutaka Hattori, Yoshikuni Mizuno, 2000, Nature Genetics.

Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases.

N. Shimizu, J. Kudoh, A. Yamaki, 2005, Experimental cell research.

Proteine parkine utilisee comme ubiquitine ligase

N. Shimizu, Y. Mizuno, 2001 .

Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene.

A. Brookes, S. Minoshima, N. Shimizu, 1998, Biochemical and biophysical research communications.

Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene

S. Minoshima, N. Shimizu, S. Asakawa, 2000, Mammalian Genome.

Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence

S. Antonarakis, K. Kawasaki, S. Minoshima, 1998, Human Genetics.

Transmembrane delivery of polypeptide hormones bypassing the intrinsic cell surface receptors: a conjugate of insulin with α2-macroglobulin (α2M) recognizing both insulin and α2M receptors and its biological activity in relation to endocytic pathways

N. Shimizu, F. Ito, S. Ito, 1984, Molecular and Cellular Endocrinology.

Two distinct types of theca cells in the medaka gonad: Germ cell‐dependent maintenance of cyp19a1‐expressing theca cells

N. Shimizu, S. Asakawa, Minoru Tanaka, 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

Mouse thymic epithelial cell lines expressing "Aire" and peripheral tissue-specific antigens reproduce in vitro negative selection of T cells.

N. Shimizu, J. Kudoh, K. Sakai, 2011, Experimental cell research.

A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.

S. Minoshima, Takashi Sasaki, N. Shimizu, 2003, Biochemical and biophysical research communications.

Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina.

S. Noda, N. Shimizu, J. Kudoh, 2003, Gene.

Mega Base Map of the Epidermal Growth Factor (EGF) Receptor Gene Flanking Regions and Structure of the Amplification Units in EGF Receptor‐hyperproducing Squamous Carcinoma Cells

K. Kawasaki, N. Shimizu, J. Kudoh, 1988, Japanese journal of cancer research : Gann.

Ex vivo Delivery of Suicide Genes into Melanoma Cells Using Epidermal Growth Factor Receptor‐specific Fab Immunogene

N. Shimizu, A. Takayanagi, Y. Mashima, 1999, Japanese journal of cancer research : Gann.

Genomics of the Pacific Oyster Crassostrea gigas

N. Shimizu, S. Asakawa, Yoko Sato, 2003 .

Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D

Fumiko Ohta, Sumio Sugano, Yuji Kohara, 2004, Nature.

PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.

Y Mizuno, S Minoshima, Y Yamamura, 2000, Journal of neural transmission. Supplementum.

HUMAN GENOME PROJECT : CURRENT STATUS, KEIO STRATEGY AND PROSPECTS

N. Shimizu, 1997 .

Binding sites on tau proteins as components for antimicrobial peptides.

N. Shimizu, J. Kudoh, N. Kobayashi, 2008, Biocontrol science.

Commensal Bacteria Regulate Thymic Aire Expression

N. Shimizu, K. Okumura, S. Habu, 2014, PloS one.

Mitogen-activated protein kinase pathway controls autoimmune regulator (AIRE) gene expression in granulo-monocyte colony stimulating factor (GM-CSF)-stimulated myelomonocytic leukemia OTC-4 cells.

N. Shimizu, S. Yamasaki, J. Kudoh, 2005, Immunology letters.

Subcellular Expression of Autoimmune Regulator Is Organized in a Spatiotemporal Manner*

N. Shimizu, K. Nakayama, J. Kudoh, 2004, Journal of Biological Chemistry.

Expression of APG-2 protein, a member of the heat shock protein 110 family, in developing rat brain

N. Shimizu, J. Kudoh, T. Ide, 2000, Neurochemistry International.

DNA diagnosis of hydatidiform mole using the polymerase chain reaction

N. Shimizu, J. Kudoh, K. Sakai, 1991, Human Genetics.

Two Cases of Unverricht-Lundborg Disease with Mutation in the Gene Encoding Cystatin B

N. Shimizu, J. Kudoh, K. Nagamine, 1998 .

Expression of AIRE gene in peripheral monocyte/dendritic cell lineage.

N. Shimizu, J. Kudoh, S. Tamiya, 2002, Immunology letters.

Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations.

S. Minoshima, N. Shimizu, N. Hattori, 1999, Parkinsonism & related disorders.

Construction and initial analysis of bacterial artificial chromosome (BAC) contigs from the sex-determining region of the platyfish Xiphophorus maculatus.

J. Volff, M. Schartl, N. Shimizu, 2002, Gene.

Genomic organization and transcripts of the zebrafish Protocadherin genes.

T. Yagi, H. Morishita, N. Shimizu, 2004, Gene.

Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains

S. Antonarakis, R. Lyle, K. Kawasaki, 2001, Human Genetics.

Identification of 36-kDa flagellar phosphoproteins associated with hamster sperm motility.

N. Shimizu, S. Yamaoka, M. Okuno, 2003, Journal of biochemistry.

Sperm‐activating proteins from unfertilized eggs of the Pacific herring, Clupea pallasii

N. Shimizu, S. Oda, K. Sakai, 1995, Development, growth & differentiation.

Assignment of the myeloperoxidase gene MPO to human chromosome 17 using somatic cell hybrids and flow-sorted chromosomes

S. Minoshima, N. Shimizu, J. Kudoh, 1988, Japanese Journal of Human Genetics.

Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland

S. Shingaki, S. Minoshima, N. Shimizu, 2009, BMC Cancer.

APECED mutations in the autoimmune regulator (AIRE) gene

S. Antonarakis, N. Shimizu, J. Kudoh, 2001, Human mutation.

Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka

Takashi Sasaki, N. Shimizu, T. Katada, 2010, Hepatology.

Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis.

A. Shiohama, Takashi Sasaki, N. Shimizu, 2008, Journal of dermatological science.

Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.

S. Minoshima, Takashi Sasaki, N. Shimizu, 2007, Genomics.

A novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21

N. Shimizu, J. Kudoh, S. Asakawa, 2014, Transgenic Research.

Role of TBX1 in human del22q11.2 syndrome

S. Minoshima, Takashi Sasaki, N. Shimizu, 2003, The Lancet.

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.

N. Shimizu, Y. Hara, M. Nishida, 2002, Molecular cell.

Simple PCR-Based DNA Microarray System To Identify Human Pathogenic Fungi in Skin

N. Shimizu, J. Kudoh, Nobuhiro Tomatsu, 2010, Journal of Clinical Microbiology.

Screening of scFv-displaying phages recognizing distinct extracellular domains of EGF receptor by target-guided proximity labeling method.

N. Shimizu, A. Takayanagi, Tetsuhiko Yoshida, 2011, Journal of immunological methods.

Structure of human holocarboxylase synthetase gene and mutation spectrum of holocarboxylase synthetase deficiency

K. Kawasaki, S. Minoshima, N. Shimizu, 2001, Human Genetics.

Positional cloning of the APECED gene

Shinsei Minoshima, Stylianos E. Antonarakis, Hamish S. Scott, 1997, Nature Genetics.

DMY is a Y-specific DM-domain gene required for male development in the medaka fish

Shuichi Asakawa, Satoshi Hamaguchi, Mitsuru Sakaizumi, 2002, Nature.

A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes

M. Schartl, M. Schmid, N. Shimizu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Severe form of juvenile corneal stromal dystrophy with homozygous R124H mutation in the keratoepithelin gene in five Japanese patients

N. Shimizu, T. Ogata, J. Kudoh, 1998, The British journal of ophthalmology.

Sperm-Activating Proteins Obtained from the Herring Eggs Are Homologous to Trypsin Inhibitors and Synthesized in Follicle Cells

N. Shimizu, N. Koibuchi, S. Oda, 1998 .

Hyper-expansion of large DNA segments in the genome of kuruma shrimp, Marsupenaeus japonicus

Mudjekeewis D. Santos, N. Shimizu, S. Asakawa, 2010, BMC Genomics.

Localization of human phosphoribosylpyrophosphate synthetase subunit I and II genes (PRPS1 and PRPS2) to different regions of the X chromosome and assignment of two PRPS1-related genes to autosomes

N. Shimizu, S. Minoshima, N. Shimizu, 1989, Somatic cell and molecular genetics.

Absence of the Candidate Male Sex-Determining Gene dmrt1b(Y) of Medaka from Other Fish Species

M. Schartl, M. Schmid, N. Shimizu, 2003, Current Biology.

Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.

S. Minoshima, A. Shiohama, Takashi Sasaki, 2007, Experimental cell research.

Human glial fibrillary acidic protein (GFAP): molecular cloning of the complete cDNA sequence and chromosomal localization (chromosome 17) of the GFAP gene

S. Minoshima, N. Shimizu, K. Sakimura, 2004, Acta Neuropathologica.

Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka.

M. Schartl, M. Schmid, Takashi Sasaki, 2006, Genome research.

Chromosomes Today

J. Volff, M. Schartl, C. Steinlein, 1997, Springer Netherlands.

Complete nucleotide sequences of mitochondrial genomes of two solitary entoprocts, Loxocorone allax and Loxosomella aloxiata: implications for lophotrochozoan phylogeny.

Takashi Sasaki, N. Shimizu, S. Asakawa, 2008, Molecular phylogenetics and evolution.

Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b.

K. Akashi, N. Shimizu, A. Yoshimura, 2013, Gene.

Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.

S. Minoshima, Takashi Sasaki, N. Shimizu, 2004, Gene.

Molecular and clinical study of 183 patients with conotruncal anomaly face syndrome

B. Morrow, P. Scambler, S. Minoshima, 1998, Human Genetics.

Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes.

L. Shaffer, B. Morrow, S. Minoshima, 2003, Human molecular genetics.

Unprecedented intraspecific diversity of the MHC class I region of a teleost medaka, Oryzias latipes

N. Shimizu, S. Asakawa, M. Kondo, 2005, Immunogenetics.

Isolated Growth Hormone Deficiency Type 1A without Apparent Growth Hormone 1 Gene Deletion

N. Shimizu, J. Kudoh, Seiji Sato, 1994 .

The minimal eukaryotic ribosomal DNA units in the primitive red alga Cyanidioschyzon merolae.

T. Kuroiwa, Y. Kohara, Takashi Sasaki, 2004, DNA research : an international journal for rapid publication of reports on genes and genomes.

Transcriptome database KK-Periome for periodontal ligament development: expression profiles of the extracellular matrix genes.

Takashi Sasaki, N. Shimizu, T. Noguchi, 2007, Gene.

Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals

N. Shimizu, N. Hattori, S. Asakawa, 1998, Annals of neurology.

Ubiquitin-Proteasome Pathway is a Key to Understanding of Nigral Degeneration in Autosomal Recessive Juvenile Parkinson’s Disease

N. Shimizu, N. Hattori, R. Takahashi, 2002 .

Duplication and transposition of the NF1 pseudogene regions on chromosomes 2, 14, and 22

S. Minoshima, N. Shimizu, M. Luijten, 2001, Human Genetics.

Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.

N. Shimizu, J. Kudoh, A. Takayanagi, 2005, Biochemical and biophysical research communications.

The genome size evolution of medaka (Oryzias latipes) and fugu (Takifugu rubripes).

Takashi Sasaki, N. Shimizu, S. Asakawa, 2007, Genes & genetic systems.

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.

Shinsei Minoshima, Kazunori Shibuya, Shuichi Asakawa, 2004, Genomics.

The Organization of the Human lmmunoglobulin Gene Locus

K. Kawasaki, S. Minoshima, N. Shimizu, 1995 .

DMRT Genes and Sex Determination in Medaka

J. Volff, M. Schartl, M. Schmid, 2004 .

The hotei mutation of medaka in the anti-Müllerian hormone receptor causes the dysregulation of germ cell and sexual development

D. Saito, Takashi Sasaki, N. Shimizu, 2007, Proceedings of the National Academy of Sciences.

Construction of a BAC library derived from the inbred Hd-rR strain of the teleost fish, Oryzias latipes.

N. Shimizu, S. Asakawa, H. Hori, 2001, Genes & genetic systems.

Identification of 36 kDa phosphoprotein in fibrous sheath of hamster spermatozoa.

N. Shimizu, S. Yamaoka, M. Okuno, 2004, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Novel PINK1 mutations in early‐onset parkinsonism

Nobutaka Hattori, Yoshikuni Mizuno, Hiroyuki Tomiyama, 2004, Annals of neurology.

Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus.

J. Volff, M. Schartl, M. Schmid, 2002, Gene.

Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n.

Yuko Saito, Mari Yoshida, Fumitoshi Ishino, 2009, American journal of human genetics.

Three novel mutations of the PAX6 gene in Japanese aniridia patients

S. Minoshima, N. Shimizu, M. Ohtsubo, 2007, Journal of Human Genetics.

Characterization of the Human ABCG1 Gene

Paul T. Tarr, I. Xenarios, N. Shimizu, 2001, The Journal of Biological Chemistry.

Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved FISH technique

S. Minoshima, N. Shimizu, Yimin Wang, 1993, Japanese Journal of Human Genetics.

Growth Stimulation of Non–Small Cell Lung Cancer Cell Lines by Antibody against Epidermal Growth Factor Receptor Promoting Formation of ErbB2/ErbB3 Heterodimers

N. Shimizu, K. Nishio, K. Takeuchi, 2007, Molecular Cancer Research.

Unique chromosomal location of amplified EGF receptor genes in EGF receptor-hyperproducing tumor cell line NA

N. Shimizu, S. Gamou, Masaru Kobayashi, 1989, Somatic cell and molecular genetics.

Expression Frequency of the Human Immunoglobulin γ Light Chain Genes and the Roles of Their Recombination Signal and Spacer Sequences

M. Tomita, K. Kawasaki, S. Minoshima, 1998 .

Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships.

M. Carl, N. Shimizu, Hayato Yokoi, 2007, Developmental biology.

Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI).

Thorsten Henrich, Makoto Furutani-Seiki, Hisato Kondoh, 2004, Methods in cell biology.

A novel third gonadotropin-releasing hormone receptor in the medaka Oryzias latipes: evolutionary and functional implications.

N. Shimizu, S. Asakawa, M. Kondo, 2003, Gene.

Purification and characterization of the 15-kDa protein from the sperm flagella of salmonid fishes

N. Shimizu, K. Inaba, H. Ohtake, 2003 .

Structural characterization of GnRH loci in the medaka genome.

N. Shimizu, S. Asakawa, M. Kondo, 2002, Gene.

Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients

S. Minoshima, N. Shimizu, N. Hattori, 1999, Annals of neurology.

The DNA sequence of medaka chromosome LG22.

Makoto Furutani-Seiki, Hisato Kondoh, Akihiro Shima, 2007, Genomics.

PURIFICATION OF SPERM-ACTIVATING PROTEIN FROM UNFERTILIZED HERRING EGGS : Developmental Biology

N. Shimizu, K. Sakai, H. Ohtake, 1990 .

UTGB/medaka: genomic resource database for medaka biology

Nobuyoshi Shimizu, Jun Yang, Atsushi Shimizu, 2007, Nucleic Acids Res..

Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner.

Takashi Sasaki, N. Shimizu, S. Watabe, 2008, Gene.

Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latipes enrolled in temperature adaptation

Takashi Sasaki, N. Shimizu, S. Watabe, 2007 .

Genomic Structure and Expression of the Soluble Guanylyl Cyclase α2 Subunit Gene in the Medaka Fish Oryzias latipes

N. Shimizu, S. Asakawa, H. Mitani, 2003 .

A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing

H. Himmelbauer, H. Lehrach, N. Shimizu, 2004, Mechanisms of Development.

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Araxi O. Urrutia, Takashi Sasaki, N. Shimizu, 2015, Nature.

DNA sequence and analysis of human chromosome 8

Stephen C. J. Parker, Sinead B. O'Leary, Christina A. Cuomo, 2006, Nature.

Insertion of β-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness

Shinsei Minoshima, Stylianos E. Antonarakis, Kazunori Shibuya, 2001, Nature Genetics.

A homozygous frameshift mutation in the murine filaggrin gene facilitates enhanced percutaneous allergen priming

A. Shiohama, Takashi Sasaki, N. Shimizu, 2009, Nature Genetics.

Mutation analyses of North American APS‐1 patients

Qiaoyi Chen, Pärt Peterson, S. Antonarakis, 1999, Human mutation.

AIRE Functions As an E 3 Ubiquitin Ligase

N. Shimizu, K. Nakayama, J. Kudoh, 2004 .

A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis.

S. Minoshima, N. Shimizu, Tetsuhiko Yoshida, 2012, Gene.

KMeyeDB: a graphical database of mutations in genes that cause eye diseases

Shinsei Minoshima, Susumu Mitsuyama, Masafumi Ohtsubo, 2010, Human mutation.

Initial characterization of an uromodulin-like 1 gene on human chromosome 21q22.3.

S. Minoshima, N. Shimizu, J. Kudoh, 2004, Biochemical and biophysical research communications.

The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.

A. Reymond, S. Antonarakis, N. Shimizu, 2002, Human molecular genetics.

Distinct genomic sequence of the CNR/Pcdhα genes in chicken

K. Kurokawa, T. Yagi, S. Hamada, 2004 .

Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q.

N. Shimizu, J. Kudoh, K. Shibuya, 2005, Biochemical and biophysical research communications.

Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes.

Yuji Kohara, Kouji Yamada, Shuichi Asakawa, 2006, Gene.

Nucleotide sequence of the MHC class I genomic region of a teleost, the medaka (Oryzias latipes)

N. Shimizu, S. Asakawa, M. Nonaka, 2002, Immunogenetics.

WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development

H. Himmelbauer, Takashi Sasaki, N. Shimizu, 2008, PLoS genetics.

Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11.

N. Shimizu, J. Kudoh, K. Shibuya, 2004, Biochemical and biophysical research communications.

Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22

M. Ekker, R. Geisler, A. Shiohama, 2007, DNA research : an international journal for rapid publication of reports on genes and genomes.

Comparing the Human and Medaka Genomes

Takashi Sasaki, N. Shimizu, 2008 .

Comparative genomics of medaka and fugu.

M. Schartl, H. Himmelbauer, Takashi Sasaki, 2006, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Methylation status and chromatin structure of the myostatin gene promoter region in the sea perch Lateolabrax japonicus (Perciformes).

N. Shimizu, A. Takayanagi, E. Abbas, 2011, Genetics and molecular research : GMR.

Progress in the clinical and molecular genetics of familial parkinsonism

S. Minoshima, N. Shimizu, N. Hattori, 2000, Neurogenetics.

Polymorphism in the parkin gene in sporadic Parkinson's disease

S. Minoshima, N. Shimizu, N. Hattori, 1999, Annals of neurology.

Novel nuclear localization signal between the two DNA‐binding zinc fingers in the human vitamin D receptor

M. Haussler, P. Jurutka, S. Minoshima, 1998, Journal of cellular biochemistry.

Assignment of the human poly(A) polymerase (PAP) gene to chromosome 14q32.1–q32.2 and isolation of a polymorphic CA repeat sequence

M. Isobe, N. Shimizu, J. Sugimoto, 1999, Journal of Human Genetics.

Molecular cloning of the m-Golsyn gene and its expression in the mouse brain.

N. Shimizu, Fumiaki Ito, E. Funakoshi, 2006, Gene expression.

Molecular cloning and characterization of gene for Golgi-localized syntaphilin-related protein on human chromosome 8q23.

N. Shimizu, S. Asakawa, A. Shimizu, 2005, Gene.

Analysis of the promoter region of human placenta-specific DSCR4 gene.

N. Shimizu, J. Kudoh, A. Yamaki, 2008, Biochimica et biophysica acta.

Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma.

H. Ideta, I. Kimura, N. Shimizu, 2004, Investigative ophthalmology & visual science.

Nucleotide sequence of BamHI family satellite DNA and its unit length polymorphism in bluegill sunfish Lepomis macrochirus

S. Minoshima, N. Shimizu, Y. Takemon, 2002, Molecular Biology Reports.

A method for evaluating phylogenetic relationship of alpha-satellite DNA suprachromosomal family by nucleotide frequency calculation.

N. Shimizu, A. Kato, M. Kato, 1999, Molecular phylogenetics and evolution.

Structure, 5'‐Upstream Sequence and Chromosomal Assignment of the Human 14.3.3 η Chain Gene in Relation to the Effects of Methamphetamine a

N. Shimizu, S. Minoshima, N. Shimizu, 1996, Annals of the New York Academy of Sciences.

Interarm interaction of DNA cruciform forming at a short inverted repeat sequence.

Y. Lyubchenko, S. Minoshima, N. Shimizu, 2003, Biophysical journal.

Flow cytometric analysis of the expression of 9A3 antigen, E‐cadherin and EGF receptor in TMK‐1 stomach cancer cells

S. Minoshima, N. Shimizu, Atsushi Ochiai, 2007, International journal of cancer.

Structure and expression of human and rat D2 dopamine receptor genes

S. Minoshima, N. Shimizu, K. Araki, 1992, Neurochemistry International.

Effect of the potential triplex DNA region on the in vitro expression of bacterial beta-lactamase gene in superhelical recombinant plasmids.

N. Shimizu, M. Kato, 1992, Journal of biochemistry.

Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy.

Y. Lyubchenko, N. Shimizu, Mikio Kato, 2002, European journal of biochemistry.

Localization of metallothionein in nuclei of growing primary cultured adult rat hepatocytes

N. Shimizu, K. Tsujikawa, R. Fukuyama, 1991, FEBS letters.

Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.

S. Kanba, S. Noda, N. Shimizu, 2005, Biochemical and biophysical research communications.

Parkin is associated with cellular vesicles

S. Minoshima, S. Noda, N. Shimizu, 2001, Journal of neurochemistry.

Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome.

H. Ohtake, N. Shimizu, S. Asakawa, 2010, Journal of bioscience and bioengineering.

Bacterial artificial chromosome library for genome‐wide analysis of Chinese hamster ovary cells

H. Ohtake, N. Shimizu, S. Asakawa, 2009, Biotechnology and bioengineering.

Stable minihairpin structures forming at minisatellite DNA isolated from yellow fin sea bream Acanthopagrus latus.

S. Minoshima, N. Shimizu, I. Yamashita, 2007, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Point Mutations (Thr240Arg and Ala311Stop) in theParkinGene

A. Brookes, S. Minoshima, N. Shimizu, 1998 .

YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.

S. Minoshima, S. Noda, N. Shimizu, 2010, Genomics.

Identification of novel tropomyosin 1 genes of pufferfish (Fugu rubripes) on genomic sequences and tissue distribution of their transcripts

S. Minoshima, N. Shimizu, S. Watabe, 2003, Molecular Biology Reports.

Rapid quantification of the heteroplasmy of mutant mitochondrial DNAs in Leber's hereditary optic neuropathy using the Invader technology.

N. Shimizu, M. Nagano, T. Egashira, 2004, Clinical biochemistry.

Analysis of eighteen deletion breakpoints in the parkin gene.

S. Minoshima, N. Shimizu, N. Hattori, 2009, Biochemical and biophysical research communications.

Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate.

J. Hayashi, A. Shiohama, Takashi Sasaki, 2014, Journal of dermatological science.

Eye disorder database “KMeyeDB”

S Minoshima, S. Minoshima, N. Shimizu, 2000, Human mutation.

In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes

N. Shimizu, J. Kudoh, Tetsuhiko Yoshida, 2014, Biology Open.

Expression of m-Golsyn/Syntabulin gene during mouse brain development

N. Shimizu, Fumiaki Ito, E. Funakoshi, 2006, Neuroscience Letters.

Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease.

N. Shimizu, N. Hattori, Y. Mizuno, 2000, Journal of neural transmission. Supplementum.

Ethylnitrosourea‐induced thymus‐defective mutants identify roles of KIAA1440, TRRAP, and SKIV2L2 in teleost organ development

Takashi Sasaki, N. Shimizu, H. Mitani, 2009, European journal of immunology.

Cot-1 banding of human chromosomes using fluorescence in situ hybridization with Cy3 labeling

S. Minoshima, N. Shimizu, Yimin Wang, 1995, Japanese Journal of Human Genetics.

Familial Parkinson's disease. Alpha-synuclein and parkin.

S. Minoshima, N. Shimizu, N. Hattori, 2001, Advances in neurology.

The KMDB/MutationView: a mutation database for human disease genes

Shinsei Minoshima, Susumu Mitsuyama, Masafumi Ohtsubo, 2001, Nucleic Acids Res..

Analysis of porcine optineurin and myocilin expression in trabecular meshwork cells and astrocytes from optic nerve head.

S. Noda, N. Shimizu, J. Kudoh, 2004, Investigative ophthalmology & visual science.

Multiple gene organization of pufferfish Fugu rubripes tropomyosin isoforms and tissue distribution of their transcripts.

S. Minoshima, N. Shimizu, S. Watabe, 2004, Gene.

Isolation and characterization of simple repeat sequences from the yellow fin sea bream Acanthopagrus latus (Sparidae)

S. Minoshima, N. Shimizu, T. Ohtani, 2005, Molecular Biology Reports.

Medaka genome mapping and sequencing : toward complete genome sequence

M. Schartl, H. Himmelbauer, Takashi Sasaki, 2004 .

Isolation of a Gene for a Metallothionein-Like Protein from Soybean

N. Shimizu, I. Kawashima, M. Chino, 1991 .

Dual promoter expression system with insulator ensures a stringent tissue-specific regulation of two reporter genes in the transgenic fish

N. Shimizu, A. Shimizu, 2013, Transgenic Research.

Recombinant human IgG antibodies recognizing distinct extracellular domains of EGF receptor exhibit different degrees of growth inhibitory effects on human A431 cancer cells.

N. Shimizu, A. Takayanagi, Tetsuhiko Yoshida, 2013, Experimental cell research.

The DNA sequence of human chromosome 22

Melanie E. Goward, Antony V. Cox, R. Durbin, 1999, Nature.

Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man.

S Minoshima, N. Shimizu, S. Minoshima, 1994, The Journal of biological chemistry.

Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells

H. Ohtake, N. Shimizu, S. Asakawa, 2009 .

A SNP resource for human chromosome 22: extracting dense clusters of SNPs from the genomic sequence.

P Sham, S Minoshima, B. Roe, 2001, Genome research.

Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence.

S. Minoshima, N. Shimizu, J. Kudoh, 2001, Gene.

Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

S. Antonarakis, N. Shimizu, S. Minoshima, 1997, Genome research.

Hox cluster genomics in the horn shark, Heterodontus francisci.

W Miller, S Minoshima, G. Wagner, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.

Nobutaka Hattori, Yoshikuni Mizuno, Takeshi Iwatsubo, 2005, Biochemical and biophysical research communications.

Keio Mutation Database for eye disease genes (KMeyeDB)

Shinsei Minoshima, Susumu Mitsuyama, Takashi Kawamura, 1999, Nucleic Acids Res..

Developmental changes in the expression of parkin and UbcR7, a parkin‐interacting and ubiquitin‐conjugating enzyme, in rat brain

S. Minoshima, N. Shimizu, Keiji Tanaka, 2001, Journal of neurochemistry.

Methylation status of ribosomal RNA gene clusters in the flow-sorted human acrocentric chromosomes

K. Kawasaki, S. Minoshima, N. Shimizu, 1992, Mammalian Genome.

Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b.

K. Akashi, N. Shimizu, A. Yoshimura, 2013, Gene.

Genomic sequences encoding two types of medaka hemopexin-like protein Wap65, and their gene expression profiles in embryos

Takashi Sasaki, N. Shimizu, S. Watabe, 2005, Journal of Experimental Biology.

Construction of BAC library for the amphibian Xenopus tropicalis.

T. Yagi, Yusuke Taguchi, N. Shimizu, 2004, Genes & genetic systems.

Two patients with atypical interstitial deletions of 8p23.1: Mapping of phenotypical traits

N. Shimizu, R. Matsuoka, N. Matsumoto, 2008, American journal of medical genetics. Part A.