G. Reed

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Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi

R. Weissleder, F. Jaffer, C. Tung, 2004, Circulation.

Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate

A. Houng, G. Reed, I. Y. Sazonova, 2007, Journal of thrombosis and haemostasis : JTH.

Plasminogen is not required for neointima formation in a mouse model of vein graft stenosis.

P. Carmeliet, G. Reed, E. Haber, 1999, Circulation research.

Atrial Natriuretic Peptide Affects Cardiac Remodeling, Function, Heart Failure, and Survival in a Mouse Model of Dilated Cardiomyopathy

A. Houng, G. Reed, I. Gladysheva, 2014, Hypertension.

Survival in a Mouse Model of Dilated Cardiomyopathy Atrial Natriuretic Peptide Affects Cardiac Remodeling

A. Houng, G. Reed, I. Gladysheva, 2013 .

Decompensated Heart Failure Is Associated With Reduced Corin Levels and Decreased Cleavage of Pro–Atrial Natriuretic Peptide

A. Houng, G. Reed, I. Gladysheva, 2011, Circulation. Heart failure.

Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface

L. Alberio, G. Reed, K. Jackson, 2002, Nature.

Antibody Targeting as a Thrombolytic Strategy

G. Reed, E. Haber, C. Bode, 1992, Annals of the New York Academy of Sciences.

A catalytic switch and the conversion of streptokinase to a fibrin-targeted plasminogen activator.

A. Houng, G. Reed, L. Hedstrom, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a plasminogen binding region in streptokinase that is necessary for the creation of a functional streptokinase-plasminogen activator complex.

G. Reed, P. Kussie, L. F. Lin, 1995, Biochemistry.

A functional analysis of the antigenicity of streptokinase using monoclonal antibody mapping and recombinant streptokinase fragments.

G. Reed, P. Kussie, B. Parhami-Seren, 1993, Journal of immunology.

The CREB leucine zipper regulates CREB phosphorylation, cardiomyopathy, and lethality in a transgenic model of heart failure.

Paul J. Wang, G. Reed, M. Aronovitz, 2007, American journal of physiology. Heart and circulatory physiology.

CHAPTER 15 – Platelet Secretion

G. Reed, 2007 .

Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution.

G. Reed, M. L. Fitzgerald, Guy L. Reed, 1999, The Biochemical journal.

Reversing the deleterious effects of α2-antiplasmin on tissue plasminogen activator therapy improves outcomes in experimental ischemic stroke

A. Houng, G. Reed, Dong Wang, 2014, Experimental Neurology.

Lipopolysaccharide Induces Scavenger Receptor A Expression in Mouse Macrophages: A Divergent Response Relative to Human THP-1 Monocyte/Macrophages1

K. Moore, M. Freeman, G. Reed, 2000, The Journal of Immunology.

Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study

Charles P. Lin, F. Jaffer, G. Reed, 2015, Theranostics.

Atrial natriuretic peptide increases inflammation, infarct size, and mortality after experimental coronary occlusion.

A. Houng, G. Reed, Pallavi Sharma, 2009, American journal of physiology. Heart and circulatory physiology.

Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy.

Charles P. Lin, R. Weissleder, F. Jaffer, 2012, Nanomedicine.

Platelet Factor XIII Increases the Fibrinolytic Resistance of Platelet-Rich Clots by Accelerating the Crosslinking of α2-Antiplasmin to Fibrin

G. Reed, E. Haber, G. Matsueda, 1992, Thrombosis and Haemostasis.

Meta-Analysis of the Relative Efficacy and Safety of Oral P2Y12 Inhibitors in Patients With Acute Coronary Syndrome.

G. Reed, R. Khouzam, R. Shah, 2017, The American journal of cardiology.

The Paradoxical Impact of Insurance Status on Interfacility Transfer Times and Outcomes in Patients with ST-Elevation Myocardial Infarction.

G. Reed, R. Khouzam, J. Jefferies, 2019, Current problems in cardiology.

Racial Difference in Symptom Onset to Door Time in ST Elevation Myocardial Infarction

G. Reed, R. Khouzam, Uzoma N. Ibebuogu, 2016, Journal of the American Heart Association.

Platelet secretory mechanisms.

G. Reed, 2004, Seminars in thrombosis and hemostasis.

Cocaine Positivity in ST-Elevation Myocardial Infarction: A True or False Association.

G. Reed, F. Thomas, R. Khouzam, 2019, The Permanente journal.

Termination of bleeding by a specific, anticatalytic antibody against plasmin

A. Houng, G. Reed, Tieqiang Zhao, 2019, Journal of thrombosis and haemostasis : JTH.

Sodium-Glucose Cotransporter-2 Inhibitors Improve Heart Failure with Reduced Ejection Fraction Outcomes by Reducing Edema and Congestion

G. Reed, I. Gladysheva, Ryan D. Sullivan, 2022, Diagnostics.

Venous stasis-induced fibrinolysis prevents thrombosis in mice: role of α2-antiplasmin.

A. Houng, G. Reed, Satish Singh, 2019, Blood.

Thrombolysis: Scientific Basis for Current Therapy

G. Reed, 2005 .

Comparison of Argatroban and Hirudin for the Reperfusion of Thrombotic Arterial Occlusion by Tissue Plasminogen Activator

R. Giugliano, G. Reed, W. Daggett, 2004, Journal of Thrombosis and Thrombolysis.

Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death

A. Houng, G. Reed, I. Gladysheva, 2020, International journal of molecular sciences.

Mapping the antigenic regions of streptokinase in humans before and after streptokinase therapy.

H. White, G. Reed, B. Parhami-Seren, 1995, Molecular immunology.

Normalizing Plasma Renin Activity in Experimental Dilated Cardiomyopathy: Effects on Edema, Cachexia, and Survival

G. Reed, I. Gladysheva, Ryan D. Sullivan, 2019, International journal of molecular sciences.

African-American women have a higher risk for developing peripartum cardiomyopathy.

G. Reed, J. Thornton, Rakesh N. Patel, 2010, Journal of the American College of Cardiology.

Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis

A. Houng, G. Reed, Dong Wang, 2016, Journal of thrombosis and haemostasis : JTH.

Inhibition of clot-bound alpha 2-antiplasmin enhances in vivo thrombolysis.

G. Reed, E. Haber, G. Matsueda, 1990, Circulation.

Protein Kinase C Phosphorylation of Syntaxin 4 in Thrombin-activated Human Platelets*

G. Reed, Sul-Hee Chung, J. Polgár, 2000, The Journal of Biological Chemistry.

Suppression of Cardiogenic Edema with Sodium–Glucose Cotransporter-2 Inhibitors in Heart Failure with Reduced Ejection Fraction: Mechanisms and Insights from Pre-Clinical Studies

G. Reed, I. Gladysheva, Ryan D. Sullivan, 2022, Biomedicines.

Soluble (Pro)Renin Receptor Levels Are Regulated by Plasma Renin Activity and Correlated with Edema in Mice and Humans with HFrEF

G. Reed, K. Ramanathan, I. Gladysheva, 2022, Biomedicines.

Novel Factor XIII Probes for Blood Coagulation Imaging

Ralph Weissleder, R. Weissleder, F. Jaffer, 2003, Chembiochem : a European journal of chemical biology.

Risk of stroke from carotid bruits.

D. Singer, G. Reed, A. Furlan, 1989, The New England journal of medicine.

Reprogrammed streptokinases develop fibrin‐targeting and dissolve blood clots with more potency than tissue plasminogen activator

A. Houng, G. Reed, L. Hedstrom, 2009, Journal of thrombosis and haemostasis : JTH.

In Experimental Dilated Cardiomyopathy Heart Failure and Survival Are Adversely Affected by a Lack of Sexual Interactions

G. Reed, I. Gladysheva, T. M. Fan, 2020, International journal of molecular sciences.

Functional characterization of monoclonal antibody inhibitors of alpha 2-antiplasmin that accelerate fibrinolysis in different animal plasmas.

G. Reed, 1997, Hybridoma.

Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli: Unique Effects of Plasminogen Activation and &agr;2-Antiplasmin Inactivation

A. Houng, G. Reed, Satish Singh, 2017, Circulation.

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Human Platelets Contain SNARE Proteins and a Sec1p Homologue That Interacts With Syntaxin 4 and Is Phosphorylated After Thrombin Activation: Implications for Platelet Secretion

A. Houng, G. Reed, M. L. Fitzgerald, 1999 .

Time-Restricted Salutary Effects of Blood Flow Restoration on Venous Thrombosis and Vein Wall Injury in Mouse and Human Subjects.

P. Libby, F. Jaffer, G. Reed, 2021, Circulation.

Development of platelet secretory granules.

G. Reed, S. M. King, 2002, Seminars in cell & developmental biology.

Regulation of nonproteolytic active site formation in plasminogen.

A. Houng, G. Reed, L. Hedstrom, 2007, Biochemistry.

Inhibition of Clot-Bound a2-Antiplasmin Enhances In Vivo Thrombolysis

G. Reed, E. Haber, G. Matsueda, 2005 .

The contribution of activated factor XIII to fibrinolytic resistance in experimental pulmonary embolism.

A. Houng, G. Reed, Guy L. Reed, 1999, Circulation.

Generation and Mechanism of Action of a Potent Inhibitor of Factor XIII Function

G. Reed, D. Lukáčová, 1995, Thrombosis and Haemostasis.

A critical role for N-ethylmaleimide-sensitive fusion protein (NSF) in platelet granule secretion.

G. Reed, J. Polgár, 1999, Blood.

Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice With Myocardial Infarction

R. Weissleder, P. Jakob, F. Jaffer, 2006, Circulation.

Adenovirus-catheter compatibility increases gene expression after delivery to porcine myocardium.

T. Guy, J. Gorman, R. Gorman, 2003, Human gene therapy.

Impact of smoking in patients undergoing transcatheter aortic valve replacement.

G. Reed, R. Khouzam, M. Agarwal, 2018, Annals of translational medicine.

Critical Role for N-ethylmaleimide – Sensitive Fusion Protein ( NSF ) in Platelet Granule Secretion By János Polgár

G. Reed, 1999 .

Catalytic Life of Activated Factor XIII in Thrombi: Implications for Fibrinolytic Resistance and Thrombus Aging

A. Houng, G. Reed, Brian R. Robinson, 2000, Circulation.

Inhibition of factor XIII activation by an anti-peptide monoclonal antibody.

G. Reed, E. Haber, G. Matsueda, 1991, Biochemistry.

An unrecognized cause of acute abdomen in peripartum cardiomyopathy.

G. Reed, Uzoma N. Ibebuogu, J. Thornton, 2008, Southern medical journal.

An unusual case of peripartum cardiomyopathy manifesting with multiple thrombo-embolic phenomena

G. Reed, J. Thornton, U. Ibebuogu, 2007, Thrombosis journal.

Association between Pulmonary Hypertension and Clinical Outcomes in Hospitalized Patients with Sickle Cell Disease

G. Reed, B. Maron, R. Oudiz, 2018, American journal of respiratory and critical care medicine.

Difficulties in studying silent ischemia.

K. Eagle, G. Reed, 1986, The New England journal of medicine.

Streptococcus uberis Plasminogen Activator (SUPA) Activates Human Plasminogen through Novel Species-specific and Fibrin-targeted Mechanisms*

A. Houng, G. Reed, I. Gladysheva, 2012, The Journal of Biological Chemistry.

Epsilon amino caproic acid inhibits streptokinase-plasminogen activator complex formation and substrate binding through kringle-dependent mechanisms.

A. Houng, G. Reed, L. F. Lin, 2000, Biochemistry.

α Domain Deletion Converts Streptokinase into a Fibrin-dependent Plasminogen Activator through Mechanisms Akin to Staphylokinase and Tissue Plasminogen Activator*

G. Reed, F. Castellino, I. Y. Sazonova, 2004, Journal of Biological Chemistry.

Chimerism Reveals a Role for the Streptokinase β-Domain in Nonproteolytic Active Site Formation, Substrate, and Inhibitor Interactions*

G. Reed, S. Chowdhry, I. Y. Sazonova, 2002, The Journal of Biological Chemistry.

Matrix Metalloproteinase-9 Mediates the Deleterious Effects of α2-Antiplasmin on Blood–Brain Barrier Breakdown and Ischemic Brain Injury in Experimental Stroke

A. Houng, G. Reed, Satish Singh, 2017, Neuroscience.

α2-Antiplasmin: New Insights and Opportunities for Ischemic Stroke

A. Houng, G. Reed, D. Wang, 2016, Seminars in Thrombosis and Hemostasis.

Can dysfunctional HDL explain high coronary artery disease risk in South Asians?

Varghese George, Sunita Dodani, G. Reed, 2008, International journal of cardiology.

Molecular mechanisms of platelet exocytosis: insights into the "secrete" life of thrombocytes.

G. Reed, M. Fitzgerald, M. L. Fitzgerald, 2000, Blood.

Generation of species-specific, rat monoclonal antibodies that bind to the kappa chain of mouse immunoglobulin.

G. Reed, 1992, Journal of immunological methods.

The Mechanism of a Bacterial Plasminogen Activator Intermediate between Streptokinase and Staphylokinase*

A. Houng, G. Reed, L. Hedstrom, 2001, The Journal of Biological Chemistry.

Vascular Disease in Mice With a Dysfunctional Circadian Clock

G. Reed, R. D. Rudic, D. Fulton, 2009, Circulation.

Non-ST Elevation Acute Coronary Syndromes: A Comprehensive Review.

G. Reed, R. Khouzam, Uzoma N. Ibebuogu, 2017, Current problems in cardiology.

Matrix Metalloproteinase-9 Expression is Enhanced by Ischemia and Tissue Plasminogen Activator and Induces Hemorrhage, Disability and Mortality in Experimental Stroke

G. Reed, Sofiyan Saleem, Dong Wang, 2021, Neuroscience.

Alpha2-Antiplasmin: The Devil You Don't Know in Cerebrovascular and Cardiovascular Disease

G. Reed, Sofiyan Saleem, Satish Singh, 2020, Frontiers in Cardiovascular Medicine.

Platelet Dense-Granule Secretion Plays a Critical Role in Thrombosis and Subsequent Vascular Remodeling in Atherosclerotic Mice

A. Houng, G. Reed, M. Brands, 2009, Circulation.

The association of carotid intima media thickness with dysfunctional HDL in South Asians

G. Reed, L. Marion, S. Dodani, 2008 .

Phosphorylation of SNAP-23 in Activated Human Platelets*

A. Houng, G. Reed, William Arbuthnot Sir Lane, 2003, Journal of Biological Chemistry.

Factor V Leiden and Risk of Ischemic Stroke in Nonvalvular Atrial Fibrillation: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study

D. Singer, A. Go, J. Selby, 2003, Journal of Thrombosis and Thrombolysis.

Renin Activity in Heart Failure with Reduced Systolic Function—New Insights

G. Reed, I. Gladysheva, Ryan D. Sullivan, 2019, International journal of molecular sciences.

Stroke Following Coronary-Artery Bypass Surgery

Daniel E. Singer, D. Singer, G. Reed, 1988 .

Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy

G. Reed, Yao Sun, I. Gladysheva, 2017, PloS one.

Sequences of antigenic epitopes of streptokinase identified via random peptide libraries displayed on phage.

G. Reed, B. Parhami-Seren, T. Keel, 1997, Journal of molecular biology.

Leucine 42 in the Fibronectin Motif of Streptokinase Plays a Critical Role in Fibrin-independent Plasminogen Activation*

A. Houng, G. Reed, S. Chowdhry, 2000, The Journal of Biological Chemistry.

Identification and structure of activated-platelet protein-1, a protein with RNA-binding domain motifs that is expressed by activated platelets.

A. Houng, G. Reed, L. Maggini, 1997, European journal of biochemistry.

Good breeding matters: in-bred rodents provide genetic insights into platelet secretion

G. Reed, 2003, Thrombosis and Haemostasis.

to Human THP-1 Monocyte/Macrophages Macrophages: A Divergent Response Relative Receptor A Expression in Mouse Lipopolysaccharide Induces Scavenger

K. Moore, M. Freeman, G. Reed, 2000 .

Structural characterization of immunodominant regions of streptokinase recognized by murine monoclonal antibodies.

G. Reed, B. Parhami-Seren, T. Keel, 1996, Hybridoma.

Alpha 2-antiplasmin causes thrombi to resist fibrinolysis induced by tissue plasminogen activator in experimental pulmonary embolism.

A. Houng, G. Reed, A. Butté, 1997, Circulation.

Accurate Prediction of False ST-Segment Elevation Myocardial Infarction: Ready for Prime Time?

G. Reed, R. Khouzam, Mason Chumpia, 2018, Current problems in cardiology.

Synergistic fibrinolysis: combined effects of plasminogen activators and an antibody that inhibits alpha 2-antiplasmin.

G. Reed, E. Haber, G. Matsueda, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Cardiac-Specific Overexpression of Catalytically Inactive Corin Reduces Edema, Contractile Dysfunction, and Death in Mice with Dilated Cardiomyopathy

A. Houng, G. Reed, I. Gladysheva, 2019, International journal of molecular sciences.

Microvascular Thrombosis, Fibrinolysis, Ischemic Injury, and Death After Cerebral Thromboembolism Are Affected by Levels of Circulating &agr;2-Antiplasmin

A. Houng, G. Reed, Dong Wang, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Munc18-Syntaxin Complexes and Exocytosis in Human Platelets*

A. Houng, G. Reed, J. Polgár, 2003, Journal of Biological Chemistry.

Structural Elements That Govern the Substrate Specificity of the Clot-dissolving Enzyme Plasmin*

G. Reed, I. Y. Sazonova, R. B. Turner, 2002, The Journal of Biological Chemistry.

Effect of Chronic Obstructive Pulmonary Disease on In-Hospital Mortality and Clinical Outcomes After ST-Segment Elevation Myocardial Infarction.

G. Reed, M. Agarwal, Nirmanmoh Bhatia, 2017, The American journal of cardiology.

A web-based tool to predict acute kidney injury in patients with ST-elevation myocardial infarction: Development, internal validation and comparison

G. Reed, F. Thomas, R. Khouzam, 2017, PloS one.

Coevolutionary patterns in plasminogen activation

G. Reed, I. Y. Sazonova, I. Gladysheva, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Zymogen activation in the streptokinase-plasminogen complex. Ile1 is required for the formation of a functional active site.

G. Reed, L. Hedstrom, S. Wang, 2000, European journal of biochemistry.

Relation of Obesity to Outcomes of Hospitalizations for Atrial Fibrillation.

G. Reed, C. Lavie, C. Kovesdy, 2019, The American journal of cardiology.

Corin Overexpression Improves Cardiac Function, Heart Failure, and Survival in Mice With Dilated Cardiomyopathy

A. Houng, G. Reed, I. Gladysheva, 2013, Hypertension.

Increases in plasma corin levels following experimental myocardial infarction reflect the severity of ischemic injury

G. Reed, Yao Sun, I. Gladysheva, 2018, PloS one.

Potential value of circulating corin levels in acute and chronic myocardial infarction.

G. Reed, Dong Wang, 2017, Journal of laboratory and precision medicine.

Possible Enzymatic Downregulation of the Natriuretic Peptide System in Patients with Reduced Systolic Function and Heart Failure: A Pilot Study

G. Reed, Xinhua Yu, K. Ramanathan, 2018, BioMed research international.

Depressed Corin Levels Indicate Early Systolic Dysfunction Before Increases of Atrial Natriuretic Peptide/B-Type Natriuretic Peptide and Heart Failure Development

G. Reed, I. Gladysheva, Dong Wang, 2016, Hypertension.

Stroke following coronary-artery bypass surgery. A case-control estimate of the risk from carotid bruits.

D. Singer, G. Reed, R. Desanctis, 1988, The New England journal of medicine.

Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis

G. Reed, I. Gladysheva, Ryan D. Sullivan, 2023, Frontiers in Cardiovascular Medicine.

A Low-Sodium Diet Boosts Ang (1–7) Production and NO-cGMP Bioavailability to Reduce Edema and Enhance Survival in Experimental Heart Failure

G. Reed, I. Gladysheva, T. M. Fan, 2021, International journal of molecular sciences.

Cardiac Remodeling in Mice With Myocardial Infarction Factor XIII Deficiency Causes Cardiac Rupture , Impairs Wound Healing , and Aggravates

R. Weissleder, P. Jakob, F. Jaffer, 2006 .

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion.

G. Reed, J. Polgár, Sul‐Hee Chung, 2002, Blood.

High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death

G. Reed, W. Gu, Hong Chen, 2016, Journal of Clinical Neuroscience.

Signaling via P2Y12 May Be Critical for Early Stabilization of Platelet Aggregates

A. Houng, G. Reed, L. Jennings, 2014, Journal of cardiovascular pharmacology.

Bivalirudin Versus Heparin Plus Glycoprotein IIb/IIIa Inhibitors in Patients with Diabetes Mellitus Undergoing Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Controlled Trials

G. Reed, S. Kar, S. Dagogo-Jack, 2015, American Journal of Cardiovascular Drugs.

Association of history of heart failure with hospital outcomes of hyperglycemic crises: Analysis from a University hospital and national cohort.

G. Reed, R. Khouzam, S. Dagogo-Jack, 2019, Journal of diabetes and its complications.

Impact of family history of coronary artery disease on in-hospital clinical outcomes in ST-segment myocardial infarction.

G. Reed, C. Lavie, R. Khouzam, 2018, Annals of translational medicine.

Mutation of lysines in a plasminogen binding region of streptokinase identifies residues important for generating a functional activator complex.

G. Reed, ‡§ Lee-Fong Lin, Saravuth Oeun, 1996, Biochemistry.