I. Henderson

R. Chaudhuri, I. Henderson, 2012, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

A systems biology approach sheds new light on Escherichia coli acid resistance

Francesco Falciani, Anna Stincone, Matthew D. Johnson, 2011, Nucleic acids research.

Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system

Gareth W. Hughes, I. Henderson, D. Ward, 2019, Nature Microbiology.

Structure-Function Characterization of the Conserved Regulatory Mechanism of the Escherichia coli M48 Metalloprotease BepA

I. Henderson, A. Cunningham, G. Kritikos, 2020, bioRxiv.

Structure-function analysis of the Escherichia coli β–barrel assembly enhancing protease BepA suggests a role for a self-inhibitory state

I. Henderson, A. Cunningham, G. Kritikos, 2019, bioRxiv.

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.

I. Henderson, D. Adams, A. Cunningham, 2015, The Journal of clinical investigation.

Identification of the Autochaperone Domain in the Type Va Secretion System (T5aSS): Prevalent Feature of Autotransporters with a β-Helical Passenger

L. Kelley, I. Henderson, F. Polticelli, 2018, Front. Microbiol..

Genomic analysis of the protein secretion systems in Clostridium acetobutylicum ATCC 824.

M. Pallen, R. Chaudhuri, I. Henderson, 2005, Biochimica et biophysica acta.

Hotspots for Initiation of Meiotic Recombination

I. Henderson, Andrew J. Tock, 2018, Front. Genet..

A Commensal Gone Bad: Complete Genome Sequence of the Prototypical Enterotoxigenic Escherichia coli Strain H10407

Nicola K. Petty, Lisa C. Crossman, M. Pallen, 2010, Journal of bacteriology.

Interacting Genomic Landscapes of REC8-Cohesin, Chromatin, and Meiotic Recombination in Arabidopsis[CC-BY]

I. Henderson, J. Higgins, Kyuha Choi, 2020, Plant Cell.

Organization of Biogenesis Genes for Aggregative Adherence Fimbria II Defines a Virulence Gene Cluster in Enteroaggregative Escherichia coli

I. Henderson, J. Nataro, W. Elias, 1999, Journal of bacteriology.

B1b Cells Recognize Protective Antigens after Natural Infection and Vaccination

I. Henderson, A. Cunningham, Charlotte N. L. Cook, 2014, Front. Immunol..

Protein secretion systems in Fusobacterium nucleatum: genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis.

S. Beatson, I. Henderson, Anthony Scott-Tucker, 2005, Biochimica et biophysica acta.

Antigen Localization Influences the Magnitude and Kinetics of Endogenous Adaptive Immune Response to Recombinant Salmonella Vaccines

I. Henderson, A. Cunningham, T. Wells, 2017, Infection and Immunity.

A secretome view of colonisation factors in Shiga toxin-encoding Escherichia coli (STEC): from enterohaemorrhagic E. coli (EHEC) to related enteropathotypes.

I. Henderson, A. Gobert, M. Desvaux, 2016, FEMS microbiology letters.

Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing

I. Henderson, R. Stockley, A. Cunningham, 2014, The Journal of experimental medicine.

Type V protein secretion: simplicity gone awry?

I. Henderson, M. Desvaux, N. J. Parham, 2004, Current issues in molecular biology.

The Type III Secretion System (T3SS)-Translocon of Atypical Enteropathogenic Escherichia coli (aEPEC) Can Mediate Adherence

I. Henderson, W. Elias, J. Bryant, 2019, Front. Microbiol..

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis

Nathaniel J. Davies, I. Henderson, A. Cunningham, 2017, Scientific Reports.

Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system

I. Henderson, A. Cunningham, J. Cole, 2020, bioRxiv.

Complete Closed Genome Sequence of Nontoxigenic Invasive Corynebacterium diphtheriae bv. mitis Strain ISS 3319

N. Loman, J. Quick, I. Henderson, 2018, Genome Announcements.

University of Birmingham Antigen localization influences the magnitude and kinetics of the endogenous adaptive immune response to recombinant Salmonella vaccines

I. Henderson, A. Cunningham, T. Wells, 2017 .

Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease

I. Henderson, P. Moss, A. Cunningham, 2018, PloS one.

Arabidopsis HEAT SHOCK FACTOR BINDING PROTEIN is required to limit meiotic crossovers and HEI10 transcription

I. Henderson, Juhyun Kim, Youngkyun Lee, 2022, The EMBO journal.

Type III secretion: what's in a name?

M. Pallen, I. Henderson, M. Desvaux, 2006, Trends in microbiology.

Distribution of the Serine Protease Autotransporters of the Enterobacteriaceae among Extraintestinal Clinical Isolates of Escherichia coli

I. Henderson, Anthony Scott-Tucker, M. Desvaux, 2005, Journal of Clinical Microbiology.

Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation

I. Henderson, T. Lithgow, A. Cunningham, 2020, eLife.

Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation

I. Henderson, M. Overduin, T. Lithgow, 2020 .

DeepTetrad: high-throughput image analysis of meiotic tetrads by deep learning in Arabidopsis thaliana.

Hyun Seob Cho, I. Henderson, Juhyun Kim, 2019, The Plant journal : for cell and molecular biology.

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane

I. Henderson, R. Vale, S. Ovchinnikov, 2016, Cell.

University of Birmingham Molecular characterisation of the vacuolating autotransporter toxin in uropathogenic escherichia coli

I. Henderson, A. Lo, D. G. Moriel, 2016 .

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

I. Henderson, A. Cunningham, I. Delany, 2017, PloS one.

SARS-CoV-2 Spike- and Nucleoprotein-Specific Antibodies Induced After Vaccination or Infection Promote Classical Complement Activation

I. Henderson, M. Drayson, A. Cunningham, 2022, Frontiers in Immunology.

The DeNovoCytosine Methyltransferase DRM2 Requires Intact UBA Domains and a Catalytically Mutated Paralog DRM3 during RNA–Directed DNA Methylation in Arabidopsisthaliana

Krystyna A. Kelly, I. Henderson, S. Jacobsen, 2010 .

Distal Bias of Meiotic Crossovers in Hexaploid Bread Wheat Reflects Spatio-Temporal Asymmetry of the Meiotic Program

I. Henderson, K. Edwards, E. Sanchez-Moran, 2021, Frontiers in Plant Science.

C‐terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA

I. Henderson, D. Linke, M. Schütz, 2010, Molecular microbiology.

Interaction of FkpA, a peptidyl-prolyl cis/trans isomerase with EspP autotransporter protein

I. Henderson, F. Ruiz-Perez, J. Nataro, 2010, Gut microbes.

Roles of Periplasmic Chaperone Proteins in the Biogenesis of Serine Protease Autotransporters of Enterobacteriaceae

I. Henderson, F. Ruiz-Perez, J. Nataro, 2009, Journal of bacteriology.

of Birmingham Organization and architecture of AggR-dependent promoters from enteroaggregative Escherichia coli

M. Pallen, I. Henderson, S. Busby, 2018 .

Anti-LPS IgA and IgG Can Inhibit Serum Killing of Pseudomonas aeruginosa in Patients with Cystic Fibrosis

I. Henderson, S. Bell, T. Wells, 2021, Infection and immunity.

A Novel Method of Serum Resistance by Escherichia coli That Causes Urosepsis

I. Henderson, T. Wells, M. Schembri, 2018, mBio.

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

I. Henderson, K. Toellner, A. Cunningham, 2018, mBio.

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Develop at Discordant Rates

I. Henderson, K. Toellner, G. Anderson, 2018 .

The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella

K. Hokamp, I. Henderson, J. Hinton, 2017, bioRxiv.

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

I. Henderson, R. Stockley, A. Cunningham, 2017, American journal of respiratory and critical care medicine.

Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults

G. Dougan, I. Henderson, M. Molyneux, 2010, Science.

MutS homologue 4 and MutS homologue 5 Maintain the Obligate Crossover in Wheat Despite Stepwise Gene Loss following Polyploidization1[CC-BY]

I. Henderson, K. Edwards, J. Higgins, 2020, Plant Physiology.

The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

G. Dougan, I. Henderson, A. Cunningham, 2009, Proceedings of the National Academy of Sciences.

Complete sequence of a 641-kb insertion of mitochondrial DNA in the Arabidopsis nuclear genome

M. Schatz, I. Henderson, Gus Waneka, 2022 .

Salmonella enterica Serovar Typhimurium Travels to Mesenteric Lymph Nodes Both with Host Cells and Autonomously

I. Henderson, A. Cunningham, V. Cerovic, 2018, The Journal of Immunology.

Systemic Flagellin Immunization Stimulates Mucosal CD103+ Dendritic Cells and Drives Foxp3+ Regulatory T Cell and IgA Responses in the Mesenteric Lymph Node

S. Akira, I. Henderson, A. Cunningham, 2012, The Journal of Immunology.

Responses in the Mesenteric Lymph Node Regulatory T Cell and IgA + Foxp3 Dendritic Cells and Drives + Mucosal CD103 Systemic Flagellin Immunization Stimulates

I. Henderson, A. Cunningham, S. Uematsu, 2012 .

T‐zone localized monocyte‐derived dendritic cells promote Th1 priming to Salmonella

I. Henderson, A. Cunningham, I. Maclennan, 2011, European journal of immunology.

CD31 Is Required on CD4+ T Cells To Promote T Cell Survival during Salmonella Infection

I. Henderson, C. Gil, A. Cunningham, 2011, The Journal of Immunology.

Salmonella Promote T Cell Survival during T Cells To + CD31 Is Required on CD4

I. Henderson, A. Cunningham, I. Maclennan, 2011 .

Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana

I. Henderson, Kyuha Choi, F. C. H. Franklin, 2022, PLoS genetics.

Meiotic recombination within plant centromeres.

I. Henderson, J. B. Fernandes, Piotr Włodzimierz, 2019, Current opinion in plant biology.

The Pic Protease of Enteroaggregative Escherichia coli Promotes Intestinal Colonization and Growth in the Presence of Mucin

I. Henderson, F. Ruiz-Perez, J. Nataro, 2009, Infection and Immunity.

Draft Whole-Genome Sequences of 10 Atypical Enteropathogenic Escherichia coli Strains Isolated in Brazil

I. Henderson, W. Elias, J. Bryant, 2018, Microbiology Resource Announcements.

The general secretory pathway: a general misnomer?

I. Henderson, Anthony Scott-Tucker, M. Desvaux, 2004, Trends in microbiology.

Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3

I. Henderson, S. Watson, D. Cox, 2016, Platelets.

University of Birmingham Human platelet activation by Escherichia coli

I. Henderson, S. Watson, D. Cox, 2016 .

Enteroaggregative escherichia coli virulence factors in traveler's diarrhea strains.

I. Henderson, J. Vila, J. Nataro, 2000, The Journal of infectious diseases.

Causing Human Intestinal Damage Plasmid-Encoded Toxin in Escherichia coli Involvement of the Enteroaggregative

A. D. Philips, I. Henderson, J. Nataro, 1999 .

Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/69

Tetsuya Hayashi, K. Kurokawa, M. Quail, 2008, Journal of bacteriology.

Chromatin Immunoprecipitation of Meiotically Expressed Proteins from Arabidopsis thaliana Flowers.

I. Henderson, Alexander R Blackwell, Kyuha Choi, 2020, Methods in molecular biology.

Natural genetic variation and hybridization in plants

I. Henderson, D. Salt, 2017, Journal of experimental botany.

Absent Bactericidal Activity of Mouse Serum against Invasive African Nontyphoidal Salmonella Results from Impaired Complement Function but Not a Lack of Antibody

I. Henderson, A. Cunningham, C. MacLennan, 2011, The Journal of Immunology.

AntibodyComplement Function but Not a Lack of Results from Impaired Salmonella against Invasive African Nontyphoidal Absent Bactericidal Activity of Mouse Serum

I. Henderson, A. Cunningham, C. MacLennan, 2011 .

RNA processing and Arabidopsis flowering time control.

R. Macknight, V. Quesada, I. Henderson, 2004, Biochemical Society transactions.

Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning

I. Henderson, Xiaoyu Zhang, S. Jacobsen, 2006, Nature Genetics.

Gardening the genome: DNA methylation in Arabidopsis thaliana

Steven E. Jacobsen, I. Henderson, S. Jacobsen, 2005, Nature Reviews Genetics.

Natural and Vaccine-Mediated Immunity to Salmonella Typhimurium is Impaired by the Helminth Nippostrongylus brasiliensis

I. Henderson, A. Cunningham, F. Brombacher, 2014, PLoS neglected tropical diseases.

Autotransporter proteins, evolution and redefining protein secretion.

I. Henderson, J. Nataro, R. Cappello, 2000, Trends in microbiology.

A conserved extended signal peptide region directs posttranslational protein translocation via a novel mechanism.

I. Henderson, Anthony Scott-Tucker, M. Desvaux, 2007, Microbiology.

The unusual extended signal peptide region of the type V secretion system is phylogenetically restricted.

I. Henderson, Anthony Scott-Tucker, M. Desvaux, 2006, FEMS microbiology letters.

Interacting genomic landscapes of REC8-cohesin, chromatin 3 and meiotic recombination in Arabidopsis thaliana 4

I. Henderson, J. Higgins, Kyuha Choi, 2020 .

Unravelling mechanisms that govern meiotic crossover formation in wheat

I. Henderson, K. Edwards, J. Higgins, 2022, Biochemical Society transactions.

Machine learning reveals conserved chromatin patterns determining meiotic recombination sites in plants

James C. Schnable, Alexandre P. Marand, I. Henderson, 2022, bioRxiv.

Transposon-Directed Insertion-Site Sequencing Reveals Glycolysis Gene gpmA as Part of the H2O2 Defense Mechanisms in Escherichia coli

P. François, K. Krause, I. Henderson, 2022, Antioxidants.

Intestinal CD103+CD11b+ cDC2 Conventional Dendritic Cells Are Required for Primary CD4+ T and B Cell Responses to Soluble Flagellin

S. Akira, I. Henderson, A. Cunningham, 2018, Front. Immunol..

Interhomolog polymorphism shapes meiotic crossover within RAC1 and RPP13 disease resistance genes

I. Henderson, Alexander R Blackwell, Kyuha Choi, 2018, bioRxiv.

RNAi, DRD1, and Histone Methylation Actively Target Developmentally Important Non-CG DNA Methylation in Arabidopsis

I. Henderson, Xiaoyu Zhang, S. Jacobsen, 2006, PLoS genetics.

A novel dispersin protein in enteroaggregative Escherichia coli.

I. Henderson, J. Nataro, P. Gounon, 2002, The Journal of clinical investigation.

Interaction of enteroaggregative Escherichia coli with salad leaves.

M. Pallen, I. Henderson, F. Ruiz-Perez, 2009, Environmental microbiology reports.

Molecular switches — the ON and OFF of bacterial phase variation

I. Henderson, P. Owen, J. Nataro, 1999, Molecular microbiology.

LI-Detector: a Method for Curating Ordered Gene-Replacement Libraries

I. Henderson, A. Cunningham, E. C. Goodall, 2022, Microbiology spectrum.

The lipoprotein DolP affects cell separation in Escherichia coli, but not as an upstream regulator of NlpD.

I. Henderson, T. Knowles, M. Glinkowska, 2022, Microbiology.

The Capsular Polysaccharide Vi from Salmonella Typhi Is a B1b Antigen

G. Dougan, I. Henderson, K. Toellner, 2012, The Journal of Immunology.

The Essential (cid:1) -Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis (cid:1)

I. Henderson, A. Cunningham, Denisse L. Leyton, 2011 .

Thymic Function Is Maintained during Salmonella-Induced Atrophy and Recovery

I. Henderson, A. Cunningham, G. Anderson, 2012, The Journal of Immunology.

FY Is an RNA 3′ End-Processing Factor that Interacts with FCA to Control the Arabidopsis Floral Transition

V. Quesada, I. Henderson, C. Dean, 2003, Cell.

PicU, a second serine protease autotransporter of uropathogenic Escherichia coli.

I. Henderson, B. Foxman, M. Desvaux, 2004, FEMS microbiology letters.

Non-caloric artificial sweeteners modulate conjugative transfer of multi-drug resistance plasmid in the gut microbiota

I. Henderson, Jianhua Guo, Zhigang Yu, 2022, Gut microbes.

Secondary structure and 1H, 13C and 15N resonance assignments of the Escherichia coli YaeT POTRA domain

I. Henderson, T. Knowles, S. Bobat, 2007, Biomolecular NMR assignments.

The need for winter in the switch to flowering.

I. Henderson, C. Dean, C. Shindo, 2003, Annual review of genetics.

Artificial sweeteners stimulate horizontal transfer of extracellular antibiotic resistance genes through natural transformation

I. Henderson, Zhigang Yu, Jianhua Guo, 2021, The ISME journal.

Alternatives to antibiotics-a pipeline portfolio review.

I. Henderson, R. Hancock, Christopher M Thomas, 2016, The Lancet. Infectious diseases.

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

I. Henderson, A. Cunningham, J. Gumbart, 2020, Nature Communications.

Understanding Infection-Induced Thrombosis: Lessons Learned From Animal Models

I. Henderson, A. Cunningham, S. Watson, 2019, Front. Immunol..

Natural variation identifies SNI1, the SMC5/6 component, as a modifier of meiotic crossover in Arabidopsis

I. Henderson, C. Underwood, Piotr A. Ziolkowski, 2021, Proceedings of the National Academy of Sciences.

Phylogenetic Analysis of Enteroaggregative and Diffusely Adherent Escherichia coli

I. Henderson, T. Whittam, J. Nataro, 1999, Infection and Immunity.

The autotransporter secretion system.

I. Henderson, M. Desvaux, N. J. Parham, 2004, Research in microbiology.

Architectures of lipid transport systems for the bacterial outer membrane

I. Henderson, R. Vale, S. Ovchinnikov, 2016, bioRxiv.

GENETICS OF HAIR AND SKIN COLOR

J. Strathern, I. Henderson, A. Rattray, 2010 .

Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue.

Michel Hébraud, Mickaël Desvaux, I. Henderson, 2009, Trends in microbiology.

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella

K. Hokamp, I. Henderson, J. Hinton, 2018, Proceedings of the National Academy of Sciences.

The De Novo Cytosine Methyltransferase DRM2 Requires Intact UBA Domains and a Catalytically Mutated Paralog DRM3 during RNA–Directed DNA Methylation in Arabidopsis thaliana

Krystyna A. Kelly, I. Henderson, S. Jacobsen, 2010, PLoS genetics.

Meiotic recombination hotspots - a comparative view.

I. Henderson, Kyuha Choi, 2015, The Plant journal : for cell and molecular biology.

Epigenetic control of meiotic recombination in plants

I. Henderson, Nataliya E. Yelina, Christophe Lambing, 2015, Science China Life Sciences.

Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis

I. Henderson, Alexander R Blackwell, Xiaoqi Feng, 2019, Current Biology.

Modification of meiotic recombination by natural variation in plants.

I. Henderson, Catherine Griffin, Emma J. Lawrence, 2017, Journal of experimental botany.

Natural variation and dosage of the HEI10 meiotic E3 ligase control Arabidopsis crossover recombination

R. Martienssen, I. Henderson, C. Underwood, 2017, Genes & development.

Quantification and Sequencing of Crossover Recombinant Molecules from Arabidopsis Pollen DNA.

I. Henderson, Kyuha Choi, Nataliya E. Yelina, 2017, Methods in molecular biology.

Role of RNA polymerase IV in plant small RNA metabolism

Pamela J. Green, Cheng Lu, Steven E. Jacobsen, 2007, Proceedings of the National Academy of Sciences.

Scott 2 mutant-RNA-dependent RNA polymerase ArabidopsisMicroRNAs and other small RNAs enriched in the data

Shivakundan Singh Tej, I. Henderson, S. Jacobsen, 2006 .

Regulation of MicroRNA-Mediated Developmental Changes by the SWR1 Chromatin Remodeling Complex1

I. Henderson, Ilha Lee, Juhyun Kim, 2016, Plant Physiology.

Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis

Krystyna A. Kelly, Luke E. Berchowitz, I. Henderson, 2015, eLife.

Control of meiotic recombination frequency in plant genomes.

I. Henderson, 2012, Current opinion in plant biology.

Diffusion-mediated HEI10 coarsening can explain meiotic crossover positioning in Arabidopsis

John A. Fozard, I. Henderson, M. Howard, 2021, Nature Communications.

The genetic and epigenetic landscape of the Arabidopsis centromeres

M. Schatz, R. Martienssen, I. Henderson, 2021, bioRxiv.

HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis

Hyun Seob Cho, I. Henderson, Juhyun Kim, 2021, Nature Plants.

CRISPR targeting of MEIOTIC-TOPOISOMERASE VIB-dCas9 to a recombination hotspot is insufficient to increase crossover frequency in Arabidopsis

I. Henderson, Sabrina Gonzalez-Jorge, Nataliya E. Yelina, 2021, bioRxiv.

MSH2 shapes the meiotic crossover landscape in relation to interhomolog polymorphism in Arabidopsis

I. Henderson, Alexander R Blackwell, J. Higgins, 2020, The EMBO journal.

ASY1 acts as a dosage-dependent antagonist of telomere-led recombination and mediates crossover interference in Arabidopsis

I. Henderson, Christophe Lambing, Andrew J. Tock, 2020, Proceedings of the National Academy of Sciences.

Interhomolog polymorphism shapes meiotic crossover within the Arabidopsis RAC1 and RPP13 disease resistance genes

I. Henderson, Alexander R Blackwell, Juhyun Kim, 2018, PLoS genetics.

Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation

R. Martienssen, I. Henderson, Joseph Simorowski, 2018, Genome research.

Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes

Thomas J. Hardcastle, G. McVean, I. Henderson, 2016, PLoS genetics.

DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis

Thomas J. Hardcastle, I. Henderson, B. Santos, 2015, Genes & development.

Contrasted Patterns of Crossover and Non-crossover at Arabidopsis thaliana Meiotic Recombination Hotspots

I. Henderson, V. Zanni, J. Drouaud, 2013, PLoS genetics.

High-throughput analysis of meiotic crossover frequency and interference via flow cytometry of fluorescent pollen in Arabidopsis thaliana

Krystyna A. Kelly, I. Henderson, D. Mann, 2013, Nature Protocols.

HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription

I. Henderson, Juhyun Kim, Youngkyun Lee, 2021, bioRxiv.

Gardening the genome: DNA methylation in Arabidopsis thaliana

I. Henderson, S. Jacobsen, S. Chan, 2005, Nature Reviews Genetics.

Spatiotemporal control of miR398 biogenesis via chromatin remodeling and kinase signaling ensures proper ovule development.

I. Henderson, Xuemei Chen, Maokai Yan, 2021, The Plant cell.

This information is current as-Induced Atrophy and Recovery Salmonella Thymic Function Is Maintained during Anderson and

I. Henderson, A. Cunningham, G. Anderson, 2012 .

Meiosis in flowering plants and other green organisms.

I. Henderson, C. J. Harrison, E. Alvey, 2010, Journal of experimental botany.

Describing Epigenomic Information in Arabidopsis

I. Henderson, 2009 .

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

Thomas J. Hardcastle, Hyun Seob Cho, R. Martienssen, 2018, Genome research.

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis transposons and gene regulatory regions

Thomas J. Hardcastle, R. Martienssen, I. Henderson, 2017, bioRxiv.

Genomic analysis of secretion systems.

M. Pallen, R. Chaudhuri, I. Henderson, 2003, Current opinion in microbiology.

A genetic screen suggests an alternative mechanism for inhibition of SecA by azide

Anna F. A. Peacock, I. Henderson, Mohammed Jamshad, 2017 .

An ARGONAUTE4-Containing Nuclear Processing Center Colocalized with Cajal Bodies in Arabidopsis thaliana

Craig S. Pikaard, Thierry Lagrange, Steven E. Jacobsen, 2006, Cell.

THE GENOME : DNA METHYLATION IN ARABIDOPSIS THALIANA

I. Henderson, S. Jacobsen, S. Chan, 2005 .

The SRA Methyl-Cytosine-Binding Domain Links DNA and Histone Methylation

I. Henderson, Xiaoyu Zhang, S. Jacobsen, 2007, Current Biology.

Dynamic Regulation of ARGONAUTE4 within Multiple Nuclear Bodies in Arabidopsis thaliana

N. Fedoroff, I. Henderson, S. Jacobsen, 2008, PLoS genetics.

Genetic screen suggests an alternative mechanism for azide-mediated inhibition of SecA

I. Henderson, Mohammed Jamshad, D. Huber, 2018, bioRxiv.

The great escape: structure and function of the autotransporter proteins.

I. Henderson, J. Nataro, F. Navarro-García, 1998, Trends in microbiology.

Genetic and epigenetic variation of transposable elements in Arabidopsis.

R. Martienssen, I. Henderson, C. Underwood, 2017, Current opinion in plant biology.

Meiotic chromosome axis remodelling is critical for meiotic recombination in Brassica rapa

I. Henderson, E. Sanchez-Moran, K. Osman, 2021, Journal of experimental botany.

Genome Sequence of the Emerging Pathogen Aeromonas caviae

S. Beatson, I. Henderson, A. Cunningham, 2010, Journal of bacteriology.

DeepTetrad: high-throughput analysis of meiotic tetrads by deep learning in plants

Hyun Seob Cho, I. Henderson, Juhyun Kim, 2019, bioRxiv.

An Ultra High-Density Arabidopsis thaliana Crossover Map That Refines the Influences of Structural Variation and Epigenetic Features

I. Henderson, D. Weigel, Tatiana R. Feuerborn, 2019, Genetics.

Epigenetic activation of meiotic recombination in Arabidopsis centromeres via loss of H3K9me2 and non-CG DNA methylation

R. Martienssen, I. Henderson, Joseph Simorowski, 2017, bioRxiv.

Interconnections between meiotic recombination and sequence polymorphism in plant genomes.

I. Henderson, Piotr A. Ziolkowski, 2017, The New phytologist.

SadA, a Trimeric Autotransporter from Salmonella enterica Serovar Typhimurium, Can Promote Biofilm Formation and Provides Limited Protection against Infection

D. Maskell, I. Henderson, A. Cunningham, 2011, Infection and Immunity.

Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042

M. Pallen, J. Parkhill, D. Rasko, 2010, PloS one.

Membrane protein architects: the role of the BAM complex in outer membrane protein assembly

I. Henderson, Anthony Scott-Tucker, T. Knowles, 2009, Nature Reviews Microbiology.

Pushing the limits of HiFi assemblies reveals centromere diversity between two Arabidopsis thaliana genomes

I. Henderson, D. Weigel, C. Lanz, 2022, bioRxiv.

Renaming protein secretion in the gram-negative bacteria.

B. Finlay, I. Henderson, J. Nataro, 2000, Trends in microbiology.

Size and Conformation Limits to Secretion of Disulfide-bonded Loops in Autotransporter Proteins*

I. Henderson, A. Cunningham, T. Wells, 2011, The Journal of Biological Chemistry.

Common themes and variations in serine protease autotransporters.

I. Henderson, C. Stathopoulos, Yihfen T. Yen, 2008, Trends in microbiology.

Discovery of an archetypal protein transport system in bacterial outer membranes

Sri H. Ramarathinam, I. Henderson, T. Lithgow, 2012, Nature Structural &Molecular Biology.

Fold and function of polypeptide transport‐associated domains responsible for delivering unfolded proteins to membranes

I. Henderson, T. Knowles, T. Palmer, 2008, Molecular microbiology.

Type 1 and 5 secretion systems and associated toxins

I. Henderson, T. Wells, 2013 .

CD103+CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin

I. Henderson, K. Toellner, A. Cunningham, 2018, Mucosal Immunology.

Weapons of mass destruction: virulence factors of the global killer enterotoxigenic Escherichia coli.

I. Henderson, Anthony Scott-Tucker, Lisa M. Cooper, 2006, FEMS microbiology letters.

DOMAINS REARRANGED METHYLTRANSFERASE3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis

Christopher J. Hale, I. Henderson, Jonathan Hetzel, 2015, Proceedings of the National Academy of Sciences.

Genotypic and Phenotypic Characterisation of Enteroaggregative Escherichia coli from Children in Rio de Janeiro, Brazil

I. Henderson, A. Cunningham, T. Wells, 2013, PloS one.

From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis

I. Henderson, Denisse L. Leyton, A. Rossiter, 2012, Nature Reviews Microbiology.

Sequencing sliced ends reveals microRNA targets

I. Henderson, S. Jacobsen, Ian R Henderson, 2008, Nature Biotechnology.

Accurate sodium bisulfite sequencing in plants

I. Henderson, S. Jacobsen, Xiaofeng Cao, 2010, Epigenetics.

REC8-cohesin, chromatin and transcription orchestrate meiotic recombination in the Arabidopsis genome

I. Henderson, Alexander R Blackwell, J. Higgins, 2019, bioRxiv.

1 REC 8-cohesin , chromatin and transcription orchestrate 1 meiotic recombination in the Arabidopsis genome 2 3

Kuo, I. Henderson, Alexander R Blackwell, 2019 .

Sequencing a piece of history: complete genome sequence of the original Escherichia coli strain

Jeffrey A Cole, Roy R Chaudhuri, N. Loman, 2017, Microbial genomics.

Sequencing a piece of history :

N. Loman, R. Chaudhuri, I. Henderson, 2017 .

Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli

S. Beatson, I. Henderson, A. Lo, 2016, Journal of bacteriology.

Laboratory adapted Escherichia coli K‐12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis

Matthew D. Johnson, I. Henderson, A. Cunningham, 2013, Molecular microbiology.

The Essential β-Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

I. Henderson, A. Cunningham, Denisse L. Leyton, 2011, Journal of bacteriology.

Control of Arabidopsis flowering: the chill before the bloom

I. Henderson, C. Dean, 2004, Development.

Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production

S. Akira, I. Henderson, K. Toellner, 2015, European journal of immunology.

Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers

I. Henderson, A. Cunningham, F. Barone, 2022, bioRxiv.

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function

I. Henderson, A. Cunningham, M. Cobbold, 2014, European journal of immunology.

Soluble flagellin, FliC, induces an Ag‐specific Th2 response, yet promotes T‐bet‐regulated Th1 clearance of Salmonella typhimurium infection

G. Dougan, I. Henderson, A. Cunningham, 2011, European journal of immunology.

An allelic series reveals essential roles for FY in plant development in addition to flowering-time control

I. Henderson, C. Dean, G. Simpson, 2005, Development.

Mice Deficient in T-bet Form Inducible NO Synthase–Positive Granulomas That Fail to Constrain Salmonella

I. Henderson, A. Cunningham, S. Watson, 2020, The Journal of Immunology.

YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium

I. Henderson, A. Cunningham, T. Wells, 2018, Infection and Immunity.

University of Birmingham Intestinal CD103CD11b cDC2 Conventional Dendritic Cells Are Required for Primary CD4 T and B Cell Responses to Soluble Flagellin

S. Akira, I. Henderson, A. Cunningham, 2018 .

University of Intestinal CD103CD11b cDC2 Conventional Dendritic Cells Are Required for Primary CD4 T and B Cell Responses to Soluble Flagellin

S. Akira, I. Henderson, A. Cunningham, 2018 .

Salmonella Induces a Switched Antibody Response without Germinal Centers That Impedes the Extracellular Spread of Infection1

I. Henderson, K. Toellner, A. Cunningham, 2007, The Journal of Immunology.

Salmonella-induced thrombi in mice develop asynchronously in the spleen and liver and are not effective bacterial traps.

I. Henderson, A. Cunningham, S. Watson, 2019, Blood.

Impedes the Extracellular Spread of Infection Response without Germinal Centers That Salmonella Induces a Switched Antibody

I. Henderson, K. Toellner, I. Maclennan, 2013 .

Addressing Research Bottlenecks to Crop Productivity.

I. Henderson, G. Hammer, P. Wittich, 2021, Trends in plant science.

Quantifying Meiotic Crossover Recombination in Arabidopsis Lines Expressing Fluorescent Reporters in Seeds Using SeedScoring Pipeline for CellProfiler.

I. Henderson, Piotr A. Ziolkowski, Nadia Kbiri, 2022, Methods in molecular biology.

Evolution and Plasticity of Genome-Wide Meiotic Recombination Rates.

I. Henderson, K. Bomblies, 2021, Annual review of genetics.

Polymorphic proteins of Chlamydia spp.--autotransporters beyond the Proteobacteria.

I. Henderson, A. Lam, Ian R. Henderson, 2001, Trends in microbiology.

The Bacterial Intimins and Invasins: A Large and Novel Family of Secreted Proteins

I. Henderson, M. Saier, Denisse L. Leyton, 2010, PloS one.

Genome-Wide Analysis of Antigen 43 (Ag43) Variants: New Insights in Their Diversity, Distribution and Prevalence in Bacteria

I. Henderson, M. Desvaux, S. Leroy, 2023, International journal of molecular sciences.

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

G. Dougan, I. Henderson, T. Lithgow, 2018, PLoS biology.

AscA (YecA) is a molecular chaperone involved in Sec-dependent protein translocation in Escherichia coli

I. Henderson, Mohammed Jamshad, P. Lund, 2020, bioRxiv.

FANCM promotes class I interfering crossovers and suppresses class II non-interfering crossovers in wheat meiosis

I. Henderson, K. Edwards, E. Sanchez-Moran, 2022, Nature Communications.

Crossover-active regions of the wheat genome are distinguished by DMC1, the chromosome axis, H3K27me3, and signatures of adaptation

I. Henderson, K. Edwards, E. Sanchez-Moran, 2021, Genome research.

DpaA Detaches Braun’s Lipoprotein from Peptidoglycan

I. Henderson, W. Vollmer, J. Gray, 2021, bioRxiv.

The orientation of a tandem POTRA domain pair, of the beta-barrel assembly protein BamA, determined by PELDOR spectroscopy.

I. Henderson, D. Norman, T. Palmer, 2009, Structure.

TraDIS-validate: a method for curating ordered gene-replacement libraries

I. Henderson, A. Cunningham, J. Cole, 2022, bioRxiv.

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

I. Henderson, A. Cunningham, J. Collet, 2021, PLoS genetics.

YhcB coordinates peptidoglycan and LPS biogenesis with phospholipid synthesis during Escherichia coli cell growth

I. Henderson, A. Cunningham, J. Collet, 2021, bioRxiv.

Iron is a ligand of SecA-like metal-binding domains in vivo

I. Henderson, P. Winn, Mohammed Jamshad, 2020, The Journal of Biological Chemistry.

Iron is a ligand of SecA-like metal-binding domains in vivo

I. Henderson, P. Winn, Mohammed Jamshad, 2019, The Journal of Biological Chemistry.

Complete Sequence of a 641-kb Insertion of Mitochondrial DNA in the Arabidopsis thaliana Nuclear Genome

Daniel B. Sloan, M. Schatz, I. Henderson, 2022, bioRxiv.

Phase-variable outer membrane proteins in Escherichia coli.

I. Henderson, M. Meehan, P. Owen, 1996, FEMS immunology and medical microbiology.

Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses

I. Henderson, K. Toellner, A. Cunningham, 2023, bioRxiv.

Virulence Functions of Autotransporter Proteins

I. Henderson, J. Nataro, 2001, Infection and Immunity.

Identification, characterization, and rescue of CRISPR/Cas9 generated wheat SPO11‐1 mutants

I. Henderson, K. Edwards, E. Sanchez-Moran, 2022, Plant biotechnology journal.

Coexpression of MEIOTIC-TOPOISOMERASE VIB-dCas9 with guide RNAs specific to a recombination hotspot is insufficient to increase crossover frequency in Arabidopsis

I. Henderson, Sabrina Gonzalez-Jorge, Nataliya E. Yelina, 2022, G3.

Differential homotypic and heterotypic interactions of antigen 43 (Ag43) variants in autotransporter-mediated bacterial autoaggregation

I. Henderson, M. Desvaux, S. Leroy, 2019, Scientific Reports.

Molecular basis for the folding of β-helical autotransporter passenger domains

I. Henderson, A. Lo, Denisse L. Leyton, 2018, Nature Communications.

A mortise–tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

Matthew D. Johnson, I. Henderson, T. Lithgow, 2014, Nature Communications.

Cross‐species chimeras reveal BamA POTRA and β‐barrel domains must be fine‐tuned for efficient OMP insertion

I. Henderson, A. Cunningham, T. Wells, 2015, Molecular microbiology.

Mutational and Topological Analysis of the Escherichia coli BamA Protein

I. Henderson, A. Cunningham, T. Wells, 2013, PloS one.

Structure and function of BamE within the outer membrane and the β‐barrel assembly machine

M. Viant, R. Chaudhuri, I. Henderson, 2011, EMBO reports.

The Escherichia coli biofilm-promoting protein Antigen 43 does not contribute to intestinal colonization.

I. Henderson, Anthony Scott-Tucker, P. Owen, 2008, FEMS microbiology letters.

Transcription of the plasmid‐encoded toxin gene from Enteroaggregative Escherichia coli is regulated by a novel co‐activation mechanism involving CRP and Fis

I. Henderson, A. Cunningham, S. Busby, 2011, Molecular microbiology.

A novel regulatory mechanism for a novel phase-variable outer membrane protein of Escherichia coli.

I. Henderson, M. Meehan, P. Owen, 1997, Advances in Experimental Medicine and Biology.

Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner

I. Henderson, Kyuha Choi, M. Gallego, 2014, Nucleic acids research.

Creating synthetic maize centromeres

I. Henderson, Ian R. Henderson, 2023, Nature Plants.

A multiomic approach to defining the essential genome of the globally important pathogen Corynebacterium diphtheriae

I. Henderson, A. Burkovski, A. Cunningham, 2023, PLoS genetics.

Nataro Proteins Virulence Functions of Autotransporter

I. Henderson, J. Nataro, P. James, 2001 .

In vitro, classical complement activation differs by disease severity and between SARS-CoV-2 antigens

I. Henderson, M. Drayson, A. Cunningham, 2021, medRxiv.

MSH2 stimulates interfering and inhibits non-interfering crossovers in response to genetic polymorphism

I. Henderson, J. Higgins, Piotr A. Ziolkowski, 2023, bioRxiv.

Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis

I. Henderson, D. Weigel, Qichao Lian, 2023, bioRxiv.

Phylogenetic Comparisons Reveal Multiple Acquisitions of the Toxin Genes by Enterotoxigenic Escherichia coli Strains of Different Evolutionary Lineages

M. Pallen, R. Chaudhuri, I. Henderson, 2006, Journal of Clinical Microbiology.

Organization and architecture of AggR‐dependent promoters from enteroaggregative Escherichia coli

M. Pallen, I. Henderson, S. Busby, 2018, Molecular microbiology.

Expression of different bacterial cytotoxins is controlled by two global transcription factors, CRP and Fis, that co-operate in a shared-recruitment mechanism.

I. Henderson, S. Busby, D. Browning, 2015, The Biochemical journal.

Bam complex associated proteins in Escherichia coli are functionally linked to 1 peptidoglycan biosynthesis , membrane fluidity and DNA replication 2 3

I. Henderson, T. Knowles, M. Glinkowska, 2023 .

Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum

I. Henderson, A. Cunningham, E. C. Goodall, 2023, bioRxiv.

Differential timing of antibody‐mediated phagocytosis and cell‐free killing of invasive African Salmonella allows immune evasion

I. Henderson, M. Drayson, A. Cunningham, 2014, European journal of immunology.

Molecular basis for the folding of β-helical autotransporter passenger domains

Matthew D. Johnson, I. Henderson, A. Lo, 2018, Nature Communications.

A generalised module for the selective extracellular accumulation of recombinant proteins

I. Henderson, A. Cunningham, T. Wells, 2012, Microbial Cell Factories.

Cycles of satellite and transposon evolution in Arabidopsis centromeres

M. Nordborg, I. Henderson, D. Weigel, 2023, Nature.

University of Birmingham Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042

D. Rasko, M. Sebaihia, N. Thomson, 2010 .

Outer membrane translocation: numerical protein secretion nomenclature in question in mycobacteria.

I. Henderson, M. Desvaux, R. Talon, 2009, Trends in Microbiology.

Prevalence of Pathogenicity Island IICFT073 Genes among Extraintestinal Clinical Isolates of Escherichia coli

S. Beatson, R. Chaudhuri, I. Henderson, 2005, Journal of Clinical Microbiology.

Dysregulated Humoral Immunity to Nontyphoidal Salmonella in

G. Dougan, I. Henderson, M. Molyneux, 2010 .

1 The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge,

Mark J. Pallen, Julian Parkhill, Roy R. Chaudhuri, 2010 .

Alternatives to antibiotics-a pipeline portfolio review.

Martha R. J. Clokie, I. Henderson, R. Hancock, 2016, The Lancet. Infectious diseases.

Differential timing of antibody‐mediated phagocytosis and cell‐free killing of invasive African Salmonella allows immune evasion

I. Henderson, M. Drayson, A. Cunningham, 2014, European journal of immunology.

Mammalian Cell Entry domains are required for bile resistance and virulence in Salmonella

I. Henderson, A. Cunningham, T. Wells, 2018, bioRxiv.

Complete genome sequence of Helicobacter pylori B128 7.13 and a single‐step method for the generation of unmarked mutations

I. Henderson, K. Dunne, Emily J. Richardson, 2019, Helicobacter.

Structure and function of BamE within the outer membrane and the β‐barrel assembly machine

M. Viant, R. Chaudhuri, I. Henderson, 2011, EMBO reports.

Transcription of the plasmid‐encoded toxin gene from Enteroaggregative Escherichia coli is regulated by a novel co‐activation mechanism involving CRP and Fis

I. Henderson, A. Cunningham, S. Busby, 2011, Molecular microbiology.

The unusual extended signal peptide region is not required for secretion and function of an Escherichia coli autotransporter.

I. Henderson, Anthony Scott-Tucker, Denisse L. Leyton, 2010, FEMS microbiology letters.

TRASH: Tandem Repeat Annotation and Structural Hierarchy

I. Henderson, Piotr Włodzimierz, Mi-Ra Hong, 2023, Bioinformatics.

Supplemental Data S 1 The SRA Methyl-Cytosine-Binding Domain Links DNA and Histone Methylation

I. Henderson, Xiaoyu Zhang, S. Jacobsen, 2022 .

The Capsular Polysaccharide Vi from Salmonella Typhi Is a B1b Antigen

G. Dougan, I. Henderson, K. Toellner, 2012, The Journal of Immunology.

Soluble flagellin, FliC, induces an Ag‐specific Th2 response, yet promotes T‐bet‐regulated Th1 clearance of Salmonella typhimurium infection

G. Dougan, I. Henderson, A. Cunningham, 2011, European journal of immunology.

Nature Genetics Advance Online Publication Arabidopsis Meiotic Crossover Hot Spots Overlap with H2a.z Nucleosomes at Gene Promoters

Thomas J. Hardcastle, Krystyna A. Kelly, G. McVean, 2022 .

Interacting genomic landscapes of REC8-cohesin, chromatin 3 and meiotic recombination in Arabidopsis thaliana 4

I. Henderson, J. Higgins, Kyuha Choi, 2020 .

DOMAINS REARRANGED METHYLTRANSFERASE3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis

Christopher J. Hale, I. Henderson, Jonathan Hetzel, 2015, Proceedings of the National Academy of Sciences.

CTAB DNA Extraction and Genotyping-by-Sequencing to Map Meiotic Crossovers in Plants.

I. Henderson, Christophe Lambing, Pallas Kuo, 2022, Methods in molecular biology.

Interaction of enteroaggregative Escherichia coli with salad leaves.

M. Pallen, I. Henderson, F. Ruiz-Perez, 2009, Environmental microbiology reports.

University of Birmingham Iron is a ligand of SecA-like metal-binding domains in vivo

I. Henderson, P. Winn, Mohammed Jamshad, 2020 .

Identification of the Autochaperone Domain in the Type Va Secretion System (T5aSS): Prevalent Feature of Autotransporters with a -Helical Passenger

L. Kelley, I. Henderson, F. Polticelli, 2020 .