A. Malavalli

发表

Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chain.

P. K. Smith, B. Manjula, A. Tsai, 2003, Bioconjugate chemistry.

Sites of modification of hemospan, a poly(ethylene glycol)-modified human hemoglobin for use as an oxygen therapeutic.

D. A. Baker, A. Malavalli, K. Vandegriff, 2008, Bioconjugate chemistry.

Impact of acellular hemoglobin‐based oxygen carriers on brain apoptosis in rats

A. Malavalli, K. Vandegriff, M. Samaja, 2014, Transfusion.

CO‐MP4, a polyethylene glycol‐conjugated haemoglobin derivative and carbon monoxide carrier that reduces myocardial infarct size in rats

A. Malavalli, K. Vandegriff, R. Winslow, 2008, British journal of pharmacology.

Comparison of PEG-modified albumin and hemoglobin in extreme hemodilution in the rat.

A. Malavalli, K. Vandegriff, R. Winslow, 2004, Journal of applied physiology.

P45: Enhanced nitrite reaction rates of MP4OX, a novel ischemic rescue therapy

A. Malavalli, K. Vandegriff, Scott D. Olsen, 2013 .

ATP release in the presence of modi fi ed cell-free hemoglobin

Russell H. Cole, A. Malavalli, K. Vandegriff, 2009 .

Hemodynamic response and oxygen transport in pigs resuscitated with maleimide-polyethylene glycol-modified hemoglobin (MP4).

A. Malavalli, K. Vandegriff, R. Winslow, 2004, Journal of applied physiology.

Interspecies hybrid HbS: complete neutralization of Val6(beta)-dependent polymerization of human beta-chain by pig alpha-chains.

D. P. Sun, B. Manjula, A. Malavalli, 2000, Journal of molecular biology.

Inhibition of βS-chain dependent polymerization by synergistic complementation of contact site perturbations of α-chain: application of semisynthetic chimeric α-chains

A. Malavalli, M. Prabhakaran, A. Acharya, 1999 .

Enhanced Molecular Volume of Conservatively Pegylated Hb: (SP-PEG5K)6-HbA is Non-Hypertensive

B. Manjula, A. Malavalli, K. Vandegriff, 2005, Artificial cells, blood substitutes, and immobilization biotechnology.

MP4, a new nonvasoactive PEG‐Hb conjugate

A. Malavalli, K. Vandegriff, R. Winslow, 2003, Transfusion.

Hemospan improves outcome in a model of perioperative hemodilution and blood loss in the rat: comparison with hydroxyethyl starch.

A. Malavalli, K. Vandegriff, R. Winslow, 2009, Journal of cardiothoracic and vascular anesthesia.

Oxidation and haem loss kinetics of poly(ethylene glycol)-conjugated haemoglobin (MP4): dissociation between in vitro and in vivo oxidation rates.

A. Malavalli, K. Vandegriff, R. Winslow, 2006, The Biochemical journal.

Perturbation of the Intermolecular Contact Regions (Molecular Surface) of Hemoglobin S by Intramolecular, Low-O2-Affinity-Inducing Central Cavity Cross-Bridges

B. Manjula, A. Malavalli, J. Friedman, 2000, Journal of protein chemistry.

Toxicity and hemodynamic effects after single dose administration of MalPEG-hemoglobin (MP4) in rhesus monkeys.

A. Malavalli, K. Vandegriff, R. Winslow, 2007, Translational research : the journal of laboratory and clinical medicine.

Cys-93-ββ-Succinimidophenyl Polyethylene Glycol 2000 Hemoglobin A

B. Manjula, A. Malavalli, J. Friedman, 2000, The Journal of Biological Chemistry.

Activation of the low oxygen affinity-inducing potential of the Asn108(β)→Lys mutation of Hb-Presbyterian on intramolecular αα-fumaryl cross-bridging

B. Manjula, A. Malavalli, J. Friedman, 2001 .

Hemoglobin extravasation in the brain of rats exchange-transfused with hemoglobin-based oxygen carriers

A. Malavalli, K. Vandegriff, G. Mkrtchyan, 2017, Artificial cells, nanomedicine, and biotechnology.

Activation of the low oxygen affinity-inducing potential of the Asn108(beta)-->Lys mutation of Hb-Presbyterian on intramolecular alpha alpha-fumaryl cross-bridging.

B. Manjula, A. Malavalli, M. Prabhakaran, 2001, Protein Engineering.

Intramolecular cross-linking of oxy hemoglobin by bis sulfosuccinimidyl suberate and sebacate: generation of cross-linked hemoglobin with reduced oxygen affinity.

P. K. Smith, B. Manjula, A. Malavalli, 1995, Artificial cells, blood substitutes, and immobilization biotechnology.

Probing the Conformation of Hemoglobin Presbyterian in the R-State

C. Ho, B. Manjula, A. Malavalli, 2003, Journal of Protein Chemistry.

Probing the diphosphoglycerate binding pocket of HbA and HbPresbyterian (beta 108Asn --> Lys).

B. Manjula, A. Malavalli, J. Friedman, 1999, Biochemistry.

Correct assembly of human normal adult hemoglobin when expressed in transgenic swine: chemical, conformational and functional equivalence with the human-derived protein.

D. P. Sun, B. Manjula, A. Malavalli, 1998, Protein engineering.

Solution structure of poly(ethylene) glycol-conjugated hemoglobin revealed by small-angle X-ray scattering: implications for a new oxygen therapeutic.

D. A. Baker, A. Malavalli, K. Vandegriff, 2008, Biophysical journal.

Correlation between Hemoglobin Oxygen Affinity and Nitrite Reductase Activity

A. Malavalli, K. Vandegriff, Scott D. Olsen, 2012 .

Erythrocytic ATP release in the presence of modified cell-free hemoglobin.

Russell H. Cole, A. Malavalli, K. Vandegriff, 2009, Biophysical chemistry.

Kinetics of NO and O2 binding to a maleimide poly(ethylene glycol)-conjugated human haemoglobin.

M. Brunori, A. Malavalli, K. Vandegriff, 2004, The Biochemical journal.

How Nitric Oxide Hindered the Search for Hemoglobin-Based Oxygen Carriers as Human Blood Substitutes

A. Malavalli, K. Vandegriff, Michele Samaja, 2023, International journal of molecular sciences.