S. Harper

S. Harper, J. Barratt, J. Feehally, 1998, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Overexpression of VEGF165b in podocytes reduces glomerular permeability.

S. Harper, D. Bates, S. Oltean, 2010, Journal of the American Society of Nephrology : JASN.

Microscopic haematuria Role of renal biopsy is undervalued

S. Harper, J. Feehally, P. Topham, 1994, BMJ.

The role of VEGF-A165b in trophoblast survival

S. Harper, D. Bates, P. Soothill, 2014, BMC Pregnancy and Childbirth.

Glomerular disease as a cause of isolated microscopic haematuria.

S. Harper, J. Feehally, J. Walls, 1994, The Quarterly journal of medicine.

Elevation of IgA in IgA nephropathy is localized in the serum and not saliva and is restricted to the IgA1 subclass.

S. Harper, J. Feehally, L. Layward, 1993, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Systemic and mucosal IgA responses to systemic antigen challenge in IgA nephropathy.

S. Harper, J. Feehally, L. Layward, 1993, Clinical immunology and immunopathology.

The pathogenic role of immunoglobulin A polymers in immunoglobulin A nephropathy.

S. Harper, J. Feehally, 1993, Nephron.

Origin and structure of pathogenic IgA in IgA nephropathy.

S. Harper, J. Feehally, A. Allen, 1997, Biochemical Society transactions.

Ovarian VEGF165b expression regulates follicular development, corpus luteum function and fertility

S. Harper, D. Bates, H. Fraser, 2011, Reproduction.

Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia

S. Harper, D. Bates, A. Millar, 2008, Clinical science.

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

M. Ladomery, S. Harper, D. Bates, 2008, Journal of Cell Science.

Balance of pro‐ versus anti‐angiogenic splice isoforms of vascular endothelial growth factor as a regulator of neuroblastoma growth

S. Harper, D. Bates, P. Ramani, 2010, The Journal of pathology.

Impaired vascular permeability regulation due to the VEGF 165 b splice variant in pre-eclampsia

S. Harper, D. Bates, P. Soothill, 2011 .

Hypogammaglobulinemia and bronchiectasis in mycophenolate mofetil‐treated renal transplant recipients: an emerging clinical phenomenon?

S. Harper, P. Boddana, C. Bingham, 2011, Clinical transplantation.

Resolution of the three dimensional structure of components of the glomerular filtration barrier

D. Bates, S. Harper, D. Bates, 2014, BMC Nephrology.

VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice.

Athina Mavrou, S. Harper, D. Bates, 2012, American journal of physiology. Renal physiology.

Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions.

S. Harper, D. Bates, W. Deen, 2007, American journal of physiology. Renal physiology.

Nifedipine improves immediate, and 6‐ and 12‐month graft function in cyclosporin A (CyA) treated renal allograft recipients

S. Harper, J. Feehally, J. Walls, 1992 .

Nifedipine improves immediate, and 6- and 12-month graft function in cyclosporin A (CyA) treated renal allograft recipients.

S. Harper, J. Feehally, J. Walls, 1992, Transplant international : official journal of the European Society for Organ Transplantation.

VEGF 165 b is an endogenous neuroprotective splice isoform of VEGF-A in vivo and in vitro .

P. Kehoe, S. Harper, D. Bates, 2012 .

Plasma from women with severe pre-eclampsia increases microvascular permeability in an animal model in vivo.

S. Harper, D. Bates, P. Soothill, 2004, Clinical science.

VEGF165b, an Inhibitory Vascular Endothelial Growth Factor Splice Variant

Marina Ziche, Lucia Morbidelli, Yan Qiu, 2004, Cancer Research.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy

G. Damodaran, S. Harper, D. Bates, 2014, Angiogenesis.

TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation

S. Harper, D. Bates, K. Wongprasert, 2014, Molecular vision.

Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury

S. Harper, D. Bates, S. Oltean, 2018, Nephron.

The beneficial effects of oral nifedipine on cyclosporin-treated renal transplant recipients — a randomised prospective study

S. Harper, K. Abrams, J. Feehally, 1996, Transplant international : official journal of the European Society for Organ Transplantation.

Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes.

S. Harper, D. Bates, R. Foster, 2005, American journal of physiology. Renal physiology.

Balancing the Wnts in Polycystic Kidney Disease

S. Harper, S. Oltean, R. Jaussi, 2010 .

Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes.

S. Harper, D. Bates, R. Foster, 2005, Journal of the American Society of Nephrology : JASN.

Novel hemodynamic structures in the human glomerulus

C. P. Winlove, S. Harper, D. Bates, 2018, American journal of physiology. Renal physiology.

Novel hemodynamic structures in the human glomerulus.

C. P. Winlove, S. Harper, D. Bates, 2018 .

Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.

S. Harper, D. Bates, S. Oltean, 2018, Comprehensive Physiology.

Alternative splicing of TIA‐1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

D. Kerr, M. Ladomery, S. Harper, 2014, Molecular oncology.

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

S. Harper, D. Bates, N. Ved, 2015, Clinical science.

A comparative study of digoxigenin, 2,4-dinitrophenyl, and alkaline phosphatase as deoxyoligonucleotide labels in non-radioisotopic in situ hybridisation.

S. Harper, J. Feehally, J. Pringle, 1997, Journal of clinical pathology.

Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation.

S. Harper, J. Feehally, M. Bottomley, 1999, Journal of clinical pathology.

Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein.

D. Gillatt, S. Harper, D. Bates, 2004, American journal of physiology. Renal physiology.

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.

M. Ladomery, S. Harper, D. Bates, 2011, Cancer cell.

Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo.

D. Gillatt, S. Harper, P. Mathieson, 2001, Clinical science.

Molecular Diversity of VEGF‐A as a Regulator of Its Biological Activity

S. Harper, D. Bates, J. Woolard, 2009, Microcirculation.

Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor.

S. Harper, S. Satchell, M. Saleem, 2002, Journal of the American Society of Nephrology : JASN.

Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant.

S. Harper, R. Harrison, P. Mathieson, 1999, Clinical science.

An Adenovirus‐Mediated Gene‐Transfer Model of Angiogenesis in Rat Mesentery

S. Harper, D. Bates, Wen-Ying Wang, 2004, Microcirculation.

Therapeutic potential of manipulating VEGF splice isoforms in oncology.

S. Harper, D. Bates, E. Rennel, 2009, Future oncology.

Differential Expression of VEGF‐Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis

S. Harper, D. Bates, S. Oltean, 2017, American journal of respiratory and critical care medicine.

SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.

S. Harper, D. Bates, M. Gammons, 2013, Investigative ophthalmology & visual science.

Expression of the mucosal γδ T cell receptor V region repertoire in patients with IgA nephropathy

John Feehally, Colleen Olive, Alice C. Allen, 1997 .

The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo

S. Harper, D. Bates, S. Oltean, 2019, RNA biology.

Visceral Glomerular Epithelial Cell DNA Synthesis in Experimental and Human Membranous Disease

S. Harper, D. Salant, J. Feehally, 1998, Nephron Experimental Nephrology.

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

Athina Mavrou, M. Ladomery, S. Harper, 2012, Biochemical Society transactions.

The anti-angiogenic isoforms of VEGF in health and disease.

S. Harper, D. Bates, S. Oltean, 2009, Biochemical Society transactions.

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia

H. Kennedy, S. Harper, D. Bates, 2014, Neurobiology of Disease.

Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms

M. Ladomery, S. Harper, D. Bates, 2009, The Journal of Biological Chemistry.

Claesson-Welsh L: Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

Lena Claesson-Welsh, S. Harper, D. Bates, 2022 .

A Role for the Endothelial Glycocalyx in Regulating Microvascular Permeability in Diabetes Mellitus

S. Harper, D. Bates, R. Perrin, 2007, Cell Biochemistry and Biophysics.

Turnover of human tubular cells exposed to proteins in vivo and in vitro.

S. Harper, J. Feehally, J. Walls, 2001, Kidney international.

Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation for J chain mRNA.

S. Harper, J. Feehally, J. Pringle, 1996, Journal of clinical pathology.

Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space.

S. Harper, D. Bates, C. Neal, 2005, Journal of the American Society of Nephrology : JASN.

In vitro immunoglobulin isotype suppression in immunoglobulin A nephropathy.

S. Harper, J. Feehally, L. Layward, 1994, Experimental nephrology.

Increased IgA and decreased IgG production by Epstein-Barr virus transformed B cells in culture in IgA nephropathy.

S. Harper, J. Feehally, L. Layward, 1994, Experimental nephrology.

The beneficial effects of oral nifedipine on cyclosporin‐treated renal transplant recipients — a randomised prospective study

S. Harper, K. Abrams, J. Feehally, 1996 .

VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy

S. Harper, D. Bates, C. Paraskeva, 2008, British Journal of Cancer.

Recombinant human VEGF165b inhibits experimental choroidal neovascularization.

S. Harper, D. Bates, S. Kase, 2010, Investigative ophthalmology & visual science.

VEGF-A165b is cytoprotective and antiangiogenic in the retina.

S. Harper, D. Bates, M. Gammons, 2010, Investigative ophthalmology & visual science.

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.

G. Damodaran, S. Harper, D. Bates, 2015, Journal of the American Society of Nephrology : JASN.

A Human Neutralizing Antibody Specific to Ang‐2 Inhibits Ocular Angiogenesis

C. Klein, Markus Thomas, S. Harper, 2011, Microcirculation.

Simultaneous in situ hybridisation of native mRNA and immunoglobulin detection by conventional immunofluorescence in paraffin wax embedded sections.

S. Harper, I. Lauder, J. Feehally, 1992, Journal of clinical pathology.

Reduced Glomerular Filtration in Diabetes Is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations

S. Harper, D. Shima, H. Band, 2022, Journal of the American Society of Nephrology : JASN.

Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx

S. Harper, R. Toto, H. Heerspink, 2023, JCI insight.

Association between VEGF Splice Isoforms and Progression-Free Survival in Metastatic Colorectal Cancer Patients Treated with Bevacizumab

P. Catalano, S. Harper, D. Bates, 2012, Clinical Cancer Research.

VEGF in the lung: a role for novel isoforms

S. Harper, D. Bates, A. Medford, 2010, American journal of physiology. Lung cellular and molecular physiology.

Influence of nifedipine on interstitial fibrosis in renal transplant allografts treated with cyclosporin A.

S. Harper, J. Feehally, J. Walls, 1994, Journal of clinical pathology.

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro.

P. Kehoe, S. Harper, D. Bates, 2013, The American journal of pathology.

Hyperglycemia Stimulates a Sustained Increase in Hydraulic Conductivity In Vivo without Any Change in Reflection Coefficient

S. Harper, D. Bates, R. Corrall, 2007, Microcirculation.

Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion

J. Oxley, S. Harper, S. Oltean, 2015, Journal of Clinical Pathology.

Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression.

Nicholas Beazley-Long, Kevin Gaston, Antonio Orlando, 2015, American journal of cancer research.

Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.

Christine J. Martin, William A. Vousden, M. Gregory, 2011, Chemical science.

Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor

S. Harper, D. Bates, A. Churchill, 2005, Diabetologia.

Human uremic plasma increases microvascular permeability to water and proteins in vivo.

S. Harper, D. Bates, C. Tomson, 2002, Kidney international.

The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.

Yan Qiu, S. Harper, D. Bates, 2006, Clinical science.

Response to mucosal antigen challenge in IgA nephropathy.

S. Harper, J. Feehally, L. Layward, 1995, Experimental nephrology.

Deficiency of IgG subclass antibody response to tetanus toxoid associated with high serum IgA levels in IgA nephropathy.

S. Harper, J. Feehally, L. Layward, 1993, Clinical nephrology.

A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties

C. Gooding, Christopher W. J. Smith, S. Harper, 2021, Oncogenesis.

Detection of VEGF-Axxxb Isoforms in Human Tissues

Athina Mavrou, S. Harper, D. Bates, 2013, PloS one.

Therapeutic potential of inhibitory VEGF splice variants.

S. Harper, D. Bates, 2005, Future oncology.

Impaired vascular permeability regulation caused by the VEGF165b splice variant in pre‐eclampsia

S. Harper, D. Bates, P. Soothill, 2011, BJOG : an international journal of obstetrics and gynaecology.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy

G. Damodaran, S. Harper, D. Bates, 2014, Angiogenesis.

S. Harper, D. Bates, C. Paraskeva, 2008, British Journal of Cancer.

Angiopoietin-1 Is Normally Expressed by Periendothelial Cells

S. Harper, S. Satchell, P. Mathieson, 2001, Thrombosis and Haemostasis.

The anti-angiogenic isoforms of VEGF in health and disease.

S. Harper, D. Bates, S. Oltean, 2009, Biochemical Society transactions.

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

Athina Mavrou, M. Ladomery, S. Harper, 2012, Biochemical Society transactions.

Overexpression of VEGF165b in mouse ovary results in reduced litter size

D. Bates, S. Harper, D. Murphy, 2009 .

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

S. Harper, D. Bates, N. Ved, 2015, Clinical science.

The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice

E. Kleinerman, D. Gillatt, S. Harper, 2008, British Journal of Cancer.

Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions.

D. Bates, S. Harper, P. Muston, 2007, American journal of physiology. Renal physiology.

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

S. Harper, D. Bates, Y. Qiu, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Improved immediate graft function with nifedipine in cyclosporine-treated renal allograft recipients--a randomized prospective study.

S. Harper, J. Feehally, J. Walls, 1992, Transplantation.

Glomerular filtration barrier and molecular segregation: guilty as charged?

S. Harper, D. Bates, 2010, Journal of the American Society of Nephrology : JASN.