D. Bates

发表

SERINE ARGININE PROTEIN KINASE-1 (SRPK1) INHIBITION AS A POTENTIAL NOVEL TARGETED THERAPEUTIC STRATEGY IN PROSTATE CANCER

J. Oxley, Athina Mavrou, K. Brakspear, 2014, Oncogene.

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD.

S. Knapp, S. Harper, D. Bates, 2013, Investigative ophthalmology & visual science.

VEGF-C promotes survival in podocytes.

S. Harper, D. Bates, R. Foster, 2006, American journal of physiology. Renal physiology.

Hallmarks of alternative splicing in cancer

D. Bates, S. Oltean, 2014, Oncogene.

Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm.

M. Ladomery, S. Harper, D. Bates, 2007, Cancer letters.

The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors.

H. Augustin, D. Bates, Sven Christian, 2006, The American journal of pathology.

VEGF-A splicing: the key to anti-angiogenic therapeutics?

Steven J. Harper, S. Harper, D. Bates, 2008, Nature Reviews Cancer.

HO-1 in Control of a Self-Eating Kidney

S. Harper, D. Bates, S. Oltean, 2010 .

The Role of Vascular Endothelial Growth Factor in Wound Healing

D. Bates, R. Jones, 2003, The international journal of lower extremity wounds.

Vascular endothelial growth factor increases hydraulic conductivity of isolated perfused microvessels.

D. Bates, F. Curry, D. Bates, 1996, The American journal of physiology.

The chronic effect of vascular endothelial growth factor on individually perfused frog mesenteric microvessels

D. Bates, 1998, The Journal of physiology.

VEGF and ATP act by different mechanisms to increase microvascular permeability and endothelial [Ca(2+)](i).

D. Bates, F. Curry, T. Pocock, 2000, American journal of physiology. Heart and circulatory physiology.

In vivo mechanisms of vascular endothelial growth factor‐mediated increased hydraulic conductivity of Rana capillaries

D. Bates, T. Pocock, David O. Bates, 2001, The Journal of physiology.

Differential Effects of Vascular Endothelial Growth Factor-C and Placental Growth Factor-1 on the Hydraulic Conductivity of Frog Mesenteric Capillaries

D. Bates, T. Pocock, B. Williams, 2001, Journal of Vascular Research.

Vascular endothelial growth factor increases Rana vascular permeability and compliance by different signalling pathways

D. Bates, F. Curry, B. Williams, 2001, The Journal of physiology.

Regulation of vascular permeability by vascular endothelial growth factors.

S. Harper, D. Bates, D O Bates, 2002, Vascular pharmacology.

VEGF 165 b , an Inhibitory Splice Variant of Vascular Endothelial Growth Factor , Is Down-Regulated in Renal Cell Carcinoma 1

D. Gillatt, S. Harper, D. Bates, 2002 .

ZM323881, a Novel Inhibitor of Vascular Endothelial Growth Factor‐Receptor‐2 Tyrosine Kinase Activity

D. Bates, S. Wedge, J. Kendrew, 2002, Microcirculation.

Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes.

D. Gillatt, S. Harper, D. Bates, 2003, American journal of physiology. Renal physiology.

The anti‐angiogenic VEGF isoform VEGF165b transiently increases hydraulic conductivity, probably through VEGF receptor 1 in vivo

S. Harper, D. Bates, C. A. Glass, 2006, Journal of Physiology.

VEGF165b, an endogenous C-terminal splice variant of VEGF, inhibits retinal neovascularization in mice.

S. Harper, D. Bates, T. Gardiner, 2006, Molecular vision.

Recombinant human VEGF165b protein is an effective anti-cancer agent in mice.

Maryam Hamdollah-Zadeh, S. Harper, D. Bates, 2008, European journal of cancer.

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function

S. Harper, D. Bates, R. Foster, 2017, The Journal of physiology.

Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space.

S. Harper, D. Bates, J. Peti-Peterdi, 2007, American journal of physiology. Renal physiology.

Lymphoedema in urological cancer.

D. Gillatt, D. Bates, A. Okeke, 2004, European urology.

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.

S. Harper, D. Bates, K. Alitalo, 2008, Cardiovascular research.

Altered ratios of pro‐ and anti‐angiogenic VEGF‐A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma

D. Bates, N. Sebire, A. Ritchie, 2016, Journal of Pathology.

VEGF121b, a new member of the VEGFxxxb family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo

D. Bates, A. Varey, S. Mather, 2009, British Journal of Cancer.

Endothelial permeability in uremia.

S. Harper, D. Bates, 2003, Kidney international. Supplement.

Sulfated galactans from the red seaweed Gracilaria fisheri exerts anti-migration effect on cholangiocarcinoma cells.

D. Bates, R. Tohtong, T. Janvilisri, 2017, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Sulfated Galactans from Red Seaweed Gracilaria fisheri Target EGFR and Inhibit Cholangiocarcinoma Cell Proliferation.

D. Bates, R. Tohtong, K. Wongprasert, 2017, The American journal of Chinese medicine.

Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs

S. Cross, S. Harper, D. Bates, 2007, Diabetologia.

CCR7 Mediates Directed Growth of Melanomas Towards Lymphatics

D. Bates, M. Emmett, S. Lanati, 2011, Microcirculation.

IL-10 regulation of macrophage VEGF production is dependent on macrophage polarisation and hypoxia.

D. Bates, A. Dick, L. Nicholson, 2010, Immunobiology.

Vascular endothelial growth factor increases the ultrafiltration coefficient in isolated intact Wistar rat glomeruli

S. Harper, D. Bates, C. Neal, 2006, The Journal of physiology.

Predictive Biomarkers and Personalized Medicine Association betweenVEGFSplice IsoformsandProgression-Free Survival in Metastatic Colorectal Cancer Patients Treated with Bevacizumab

P. Catalano, S. Harper, D. Bates, 2012 .

Non‐invasive measurement of retinal permeability in a diabetic rat model

D. Bates, K. Arkill, C. Allen, 2020, Microcirculation.

Arteriolar Genesis and Angiogenesis Induced by Endothelial Nitric Oxide Synthase Overexpression Results in a Mature Vasculature

S. Harper, D. Bates, J. Uney, 2008, Arteriosclerosis, thrombosis, and vascular biology.

VEGF‐A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF‐A splice isoforms from the kidney

S. Harper, D. Bates, S. Oltean, 2017, The Journal of physiology.

Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction.

S. Harper, D. Bates, J. Peti-Peterdi, 2012, Journal of the American Society of Nephrology : JASN.

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

S. Harper, D. Bates, Y. Qiu, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

VEGF and Angiopoietin‐1 Stimulate Different Angiogenic Phenotypes That Combine to Enhance Functional Neovascularization in Adult Tissue

S. Harper, D. Bates, J. Uney, 2006, Microcirculation.

VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma.

D. Gillatt, S. Harper, D. Bates, 2002, Cancer research.

Measurement of Hydraulic Conductivity of Single Perfused Rana Mesenteric Microvessels between Periods of Controlled Shear Stress

D. Bates, C. Neal, C. Neal, 2002, The Journal of physiology.

Activation of Notch signaling by soluble Dll4 decreases vascular permeability via a cAMP/PKA-dependent pathway.

D. Bates, Maria J C Machado, L. Leach, 2019, American journal of physiology. Heart and circulatory physiology.

The mutant p 53 -ID 4 complex controls VEGFA isoforms by recruiting lncRNA MALAT 1

S. Bicciato, D. Bates, G. Blandino, 2017 .

Inhibition of serine/arginine-rich protein kinase-1 (SRPK1) prevents cholangiocarcinoma cells induced angiogenesis.

D. Bates, R. Tohtong, T. Janvilisri, 2022, Toxicology in vitro : an international journal published in association with BIBRA.

IL-4 regulates specific Arg-1(+) macrophage sFlt-1-mediated inhibition of angiogenesis.

D. Bates, A. Dick, A. Georgiadis, 2015, The American journal of pathology.

Can the co‐dependence of the immune system and angiogenesis facilitate pharmacological targeting of tumours?

D. Bates, D. Noonan, L. Mortara, 2017, Current opinion in pharmacology.

The Alternatively Spliced Anti-Angiogenic Family of VEGF Isoforms VEGFxxxb in Human Kidney Development

S. Harper, D. Bates, A. G. Gittenberger-de Groot, 2008, Nephron Physiology.

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy

D. Bates, K. Alitalo, R. Foster, 2018, Diabetes.

Measurement of angiogenic phenotype by use of two-dimensional mesenteric angiogenesis assay.

D. Bates, A. Benest, 2009, Methods in molecular biology.

Vascular endothelial growth factor-C, a potential paracrine regulator of glomerular permeability, increases glomerular endothelial cell monolayer integrity and intracellular calcium.

D. Bates, R. Foster, S. Satchell, 2008, The American journal of pathology.

Angiopoietin-1 alters microvascular permeability coefficients in vivo via modification of endothelial glycocalyx

S. Harper, D. Bates, C. Neal, 2009, Cardiovascular research.

Activity Coreceptor Binding and Deficient Regulation of Kinase Agonist for VEGF Receptor-2 Due to Lack of In vitro Vascular Endothelial Growth Factor ( VEGF )-A 165 b Is a Weak

S. Harper, D. Bates, L. Claesson‐Welsh, 2008 .

Antiangiogenic Actions of Vascular Endothelial Growth Factor-A165b, an Inhibitory Isoform of Vascular Endothelial Growth Factor-A, in Human Obesity

D. Bates, D. Hess, M. LaValley, 2014, Circulation.

Overexpression of VEGF165b in podocytes reduces glomerular permeability.

S. Harper, D. Bates, S. Oltean, 2010, Journal of the American Society of Nephrology : JASN.

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation

A. Noël, D. Bates, M. Gammons, 2012, Angiogenesis.

The role of VEGF-A165b in trophoblast survival

S. Harper, D. Bates, P. Soothill, 2014, BMC Pregnancy and Childbirth.

An interstitial hypothesis for breast cancer related lymphoedema.

D. Bates, 2010, Pathophysiology : the official journal of the International Society for Pathophysiology.

Enhanced notch signaling modulates unproductive revascularization in response to nitric oxide‐angiopoietin signaling in a mouse model of peripheral ischemia

D. Bates, Maria J C Machado, C. Emanueli, 2019, Microcirculation.

Differential regulation of blood flow‐induced neovascularization and mural cell recruitment by vascular endothelial growth factor and angiopoietin signalling

D. Bates, Maria J C Machado, P. Lin, 2016, The Journal of physiology.

Sensory neuronal sensitisation occurs through HMGB-1–RAGE and TRPV1 in high-glucose conditions

D. Bates, N. Ved, L. Donaldson, 2018, Journal of Cell Science.

The Effect of Hosiery on Interstitial Fluid Pressure and Arm Volume Fluctuations in Breast Cancer Related Arm Oedema

D. Bates, P. Mortimer, J. R. Levick, 1995 .

A TRPC-like non-selective cation current activated by alpha 1-adrenoceptors in rat mesenteric artery smooth muscle cells.

Jules C Hancox, D. Bates, J. Hancox, 2006, Cell calcium.

Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells.

D. Bates, R. Foster, S. Satchell, 2009, Cell calcium.

VEGF‐Mediated Elevated Intracellular Calcium and Angiogenesis in Human Microvascular Endothelial Cells In Vitro are Inhibited by Dominant Negative TRPC6

D. Bates, J. Hancox, Anette L Magnussen, 2008, Microcirculation.

Evidence of a role for TRPC channels in VEGF-mediated increased vascular permeability in vivo.

D. Bates, R. Foster, T. Pocock, 2004, American journal of physiology. Heart and circulatory physiology.

Regulation of microvascular permeability by vascular endothelial growth factors *

D. Bates, C. Neal, T. Pocock, 2002, Journal of anatomy.

An unexpected tail of VEGF and PlGF in pre-eclampsia.

D. Bates, 2011, Biochemical Society transactions.

Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway.

D. Bates, F. Curry, F. Curry, 1997, The American journal of physiology.

Diabetes‐induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain

D. Bates, N. Ved, M. Hirashima, 2018, The Journal of physiology.

VEGF Activates Receptor-Operated Cation Channels in Human Microvascular Endothelial Cells

D. Bates, J. Hancox, R. Foster, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Regulation of human feto-placental endothelial barrier integrity by vascular endothelial growth factors: competitive interplay between VEGF-A165a, VEGF-A165b, PIGF and VE-cadherin

D. Bates, L. Leach, V. Pang, 2017, Clinical science.

Ovarian VEGF165b expression regulates follicular development, corpus luteum function and fertility

S. Harper, D. Bates, H. Fraser, 2011, Reproduction.

BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase)

D. Bates, G. Biglino, J. Saif, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Local microvascular leakage promotes trafficking of activated neutrophils to remote organs

D. Bates, D. Vestweber, A. Nottebaum, 2020, The Journal of clinical investigation.

Transient Osmotic Absorption of Fluid in Microvessels Exposed to Low Concentrations of Dimethyl Sulfoxide

D. Bates, C. A. Glass, R. Perrin, 2006, Microcirculation.

Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia

S. Harper, D. Bates, A. Millar, 2008, Clinical science.

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

M. Ladomery, S. Harper, D. Bates, 2008, Journal of Cell Science.

Balance of pro‐ versus anti‐angiogenic splice isoforms of vascular endothelial growth factor as a regulator of neuroblastoma growth

S. Harper, D. Bates, P. Ramani, 2010, The Journal of pathology.

Faculty Opinions recommendation of The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells.

D. Bates, 2006 .

Impaired vascular permeability regulation due to the VEGF 165 b splice variant in pre-eclampsia

S. Harper, D. Bates, P. Soothill, 2011 .

Measurement of Angiogenesis, Arteriolargenesis, and Lymphangiogenesis Phenotypes by Use of Two-Dimensional Mesenteric Angiogenesis Assay.

D. Bates, A. Benest, 2016, Methods in molecular biology.

Resolution of the three dimensional structure of components of the glomerular filtration barrier

D. Bates, S. Harper, D. Bates, 2014, BMC Nephrology.

VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice.

Athina Mavrou, S. Harper, D. Bates, 2012, American journal of physiology. Renal physiology.

Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions.

S. Harper, D. Bates, W. Deen, 2007, American journal of physiology. Renal physiology.

3-D reconstruction of the glomerular barrier and overlying podocyte reveals a sub-podocyte space: a new urinary space within the glomerulus?

D. Bates, C. Neal, S. Harper, 2003 .

Consensus guidelines for the use and interpretation of angiogenesis assays

Robert J. Griffin, Federico Bussolino, Mark J. Post, 2018, Angiogenesis.

Critical Role of Tissue Kallikrein in Vessel Formation and Maturation: Implications for Therapeutic Revascularization

D. Bates, P. Quax, A. Al Haj Zen, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Novel insight into the pathophysiology of breast-cancer-related lymphoedema.

D. Bates, 2001, Clinical science.

VEGF 165 b is an endogenous neuroprotective splice isoform of VEGF-A in vivo and in vitro .

P. Kehoe, S. Harper, D. Bates, 2012 .

Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities

D. Bates, Z. Dlamini, A. Kaufmann, 2022, Microorganisms.

Plasma from women with severe pre-eclampsia increases microvascular permeability in an animal model in vivo.

S. Harper, D. Bates, P. Soothill, 2004, Clinical science.

VEGF165b, an Inhibitory Vascular Endothelial Growth Factor Splice Variant

Marina Ziche, Lucia Morbidelli, Yan Qiu, 2004, Cancer Research.

Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)

D. Bates, G. Welsh, A. Millar, 2018, Respiratory Research.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy

G. Damodaran, S. Harper, D. Bates, 2014, Angiogenesis.

TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation

S. Harper, D. Bates, K. Wongprasert, 2014, Molecular vision.

Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury

S. Harper, D. Bates, S. Oltean, 2018, Nephron.

Splicing factor polymorphisms, the control of VEGF isoforms and association with angiogenic eye disease.

D. Bates, A. Churchill, S. Turner, 2011, Current eye research.

Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes.

S. Harper, D. Bates, R. Foster, 2005, American journal of physiology. Renal physiology.

Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes.

S. Harper, D. Bates, R. Foster, 2005, Journal of the American Society of Nephrology : JASN.

Novel hemodynamic structures in the human glomerulus

C. P. Winlove, S. Harper, D. Bates, 2018, American journal of physiology. Renal physiology.

Novel hemodynamic structures in the human glomerulus.

C. P. Winlove, S. Harper, D. Bates, 2018 .

Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.

S. Harper, D. Bates, S. Oltean, 2018, Comprehensive Physiology.

Lymphatic density and metastatic spread in human malignant melanoma

D. Bates, P. Mortimer, S. Harper, 2004, British Journal of Cancer.

Alternative splicing of TIA‐1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

D. Kerr, M. Ladomery, S. Harper, 2014, Molecular oncology.

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

S. Harper, D. Bates, N. Ved, 2015, Clinical science.

Pharmacology of Modulators of Alternative Splicing

D. Bates, S. Oltean, Jonathan C. Morris, 2017, Pharmacological Reviews.

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma

D. Bates, J. H. Park, A. Greenhough, 2015, Oncotarget.

The mutant p53‐ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

S. Bicciato, D. Bates, G. Blandino, 2017, EMBO Reports.

Title : The mutant p 53-ID 4 complex controls VEGFA isoforms production by recruiting lncRNA MALAT 1

S. Bicciato, D. Bates, G. Blandino, 2017 .

The mutant p 53-ID 4 complex controls VEGFA isoforms production by 3 recruiting lncRNA MALAT 1

S. Bicciato, D. Bates, G. Blandino, 2017 .

Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata

D. Bates, N. Mongan, M. Meyer, 2020, Frontiers in Oncology.

Chemotrap-1: an engineered soluble receptor that blocks chemokine-induced migration of metastatic cancer cells in vivo.

D. Bates, M. Emmett, J. Girard, 2010, Cancer research.

Cancer esearch or and Stem Cell Biology motrap-1 : An Engineered Soluble Receptor That Blocks mokine-Induced Migration of Metastatic R cer Cells In vivo

D. Bates, M. Emmett, J. Girard, 2010 .

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

D. Kerr, B. Spencer‐Dene, H. Clevers, 2019, Oncogenesis.

An anti-angiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease

D. Bates, Kazuto Nakamura, T. Murohara, 2014, Nature Medicine.

Cervical cancer in low and middle-income countries

R. Mehrotra, D. Bates, R. Reis, 2020, Oncology letters.

Vascular endothelial growth factors and vascular permeability

D. Bates, 2010, Cardiovascular research.

Functional distinctions in cytosolic calcium regulation between cells of the glomerular filtration barrier

D. Bates, R. Foster, S. Satchell, 2010, Cell calcium.

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

Andrew J. Bannister, S. Robson, J. Marioni, 2018, Nature Communications.

VASCULAR BIOLOGY, ATHEROSCLEROSIS, AND ENDOTHELIUM BIOLOGY IL-4 Regulates Specific Arg-1 D Macrophage sFlt-1eMediated Inhibition of Angiogenesis

D. Bates, A. Dick, A. Georgiadis, 2015 .

Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein.

D. Gillatt, S. Harper, D. Bates, 2004, American journal of physiology. Renal physiology.

Vascular Endothelial Growth Factor and Microvascular Permeability

D. Bates, D. Lodwick, B. Williams, 1999, Microcirculation.

Intravital video‐capillaroscopy for the study of the microcirculation in psoriasis

D. Bates, P S Mortimer, D O Bates, 1992, The British journal of dermatology.

Regulation of vascular endothelial growth factor in prostate cancer.

D. Bates, N. Mongan, J. Persson, 2015, Endocrine-related cancer.

Mechanisms regulating angiogenesis underlie seasonal control of pituitary function

D. Bates, D. Tortonese, J. Castle-Miller, 2017, Proceedings of the National Academy of Sciences.

de Brot, Simone and Ntekim, Atara and Cardenas, Ryan and James, Victoria and Allegrucci, Cinzia and Heery, David M. and Bates, David O. and Ødum, Niels and Persson, Jenny L. and Mongan,

D. Bates, N. Mongan, J. Persson, 2016 .

Regulation of vascular endothelial growth factor ( VEGF ) in prostate cancer 1 2

D. Bates, N. Mongan, J. Persson, 2015 .

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.

M. Ladomery, S. Harper, D. Bates, 2011, Cancer cell.

Molecular Diversity of VEGF‐A as a Regulator of Its Biological Activity

S. Harper, D. Bates, J. Woolard, 2009, Microcirculation.

An Adenovirus‐Mediated Gene‐Transfer Model of Angiogenesis in Rat Mesentery

S. Harper, D. Bates, Wen-Ying Wang, 2004, Microcirculation.

Therapeutic potential of manipulating VEGF splice isoforms in oncology.

S. Harper, D. Bates, E. Rennel, 2009, Future oncology.

Differential Expression of VEGF‐Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis

S. Harper, D. Bates, S. Oltean, 2017, American journal of respiratory and critical care medicine.

SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.

S. Harper, D. Bates, M. Gammons, 2013, Investigative ophthalmology & visual science.

VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis

D. Bates, Catherine E Moss, M. Hirashima, 2018, Brain, Behavior, and Immunity.

Chemokine-mediated migration of melanoma cells towards lymphatics – a mechanism contributing to metastasis

D. Bates, M. Emmett, K. Joory, 2007, Oncogene.

South African Herbal Extracts as Potential Chemopreventive Agents: Screening for Anticancer Splicing Activity.

D. Bates, Z. Mbita, Zodwa Dlamini, 2016, Methods in molecular biology.

The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo

S. Harper, D. Bates, S. Oltean, 2019, RNA biology.

Hydrogen Sulfide Is a Novel Protector of the Retinal Glycocalyx and Endothelial Permeability Barrier

D. Bates, M. Whiteman, M. Wood, 2021, Frontiers in Cell and Developmental Biology.

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

Athina Mavrou, M. Ladomery, S. Harper, 2012, Biochemical Society transactions.

The anti-angiogenic isoforms of VEGF in health and disease.

S. Harper, D. Bates, S. Oltean, 2009, Biochemical Society transactions.

Targeting the angiogenic 'splice' switch; inhibition of SRPK1 as a novel therapeutic approach in prostate cancer

D. Bates, S. Oltean, J. Batson, 2015 .

Expression of VEGFxxxb, the inhibitory isoforms of VEGF, in malignant melanoma

D. Bates, A. Varey, Y. Qiu, 2007, British Journal of Cancer.

The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice

E. Kleinerman, D. Gillatt, S. Harper, 2008, British Journal of Cancer.

Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells

A. Mukherjee, D. Bates, R. Tohtong, 2020, Cancer research and treatment : official journal of Korean Cancer Association.

Open Access Research Article Prediction of Melanoma Metastasis by the Shields Index Based on Lymphatic Vessel Density

D. Bates, C. Metcalfe, M. Emmett, 2022 .

Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

Jules C Hancox, Stefan Knapp, Jennifer Batson, 2017, ACS chemical biology.

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia

H. Kennedy, S. Harper, D. Bates, 2014, Neurobiology of Disease.

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma

D. Bates, S. Oltean, M. Gammons, 2014, British Journal of Cancer.

UNCORRECTED PROOF 1 Regulation of alternative VEGF-A mRNA splicing is a therapeutic target 2 for analgesia☆

H. Kennedy, D. Bates, L. Donaldson, 2014 .

Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms

M. Ladomery, S. Harper, D. Bates, 2009, The Journal of Biological Chemistry.

Claesson-Welsh L: Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

Lena Claesson-Welsh, S. Harper, D. Bates, 2022 .

Co-Clinical Trials: An Innovative Drug Development Platform for Cholangiocarcinoma

D. Bates, R. Tohtong, S. Kumkate, 2021, Pharmaceuticals.

A Role for the Endothelial Glycocalyx in Regulating Microvascular Permeability in Diabetes Mellitus

S. Harper, D. Bates, R. Perrin, 2007, Cell Biochemistry and Biophysics.

Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space.

S. Harper, D. Bates, C. Neal, 2005, Journal of the American Society of Nephrology : JASN.

Structural assessment of SARS-CoV2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential

D. Bates, J. Emsley, K. Arkill, 2020, Bioscience reports.

A multinational review: Oesophageal cancer in low to middle-income countries

R. Mehrotra, D. Bates, R. Reis, 2020, Oncology letters.

VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy

S. Harper, D. Bates, C. Paraskeva, 2008, British Journal of Cancer.

Recombinant human VEGF165b inhibits experimental choroidal neovascularization.

S. Harper, D. Bates, S. Kase, 2010, Investigative ophthalmology & visual science.

Hypoxia induced carbonic anhydrase mediated dorsal horn sensory neuron activation and induction of neuropathic pain

D. Bates, M. Hirashima, R. Madden, 2021, bioRxiv.

VEGF-A165b is cytoprotective and antiangiogenic in the retina.

S. Harper, D. Bates, M. Gammons, 2010, Investigative ophthalmology & visual science.

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.

G. Damodaran, S. Harper, D. Bates, 2015, Journal of the American Society of Nephrology : JASN.

The prevalence of arm oedema following treatment for breast cancer

D. Strachan, D. Bates, P. Mortimer, 1996 .

Change in macromolecular composition of interstitial fluid from swollen arms after breast cancer treatment, and its implications.

D. Bates, P. Mortimer, P S Mortimer, 1993, Clinical science.

Quantification of rate and depth of pitting in human edema using an electronic tonometer.

D. Bates, P. Mortimer, J. R. Levick, 1994, Lymphology.

Subcutaneous interstitial fluid pressure and arm volume in lymphoedema.

D. Bates, P. Mortimer, P S Mortimer, 1992, International journal of microcirculation, clinical and experimental.

A Human Neutralizing Antibody Specific to Ang‐2 Inhibits Ocular Angiogenesis

C. Klein, Markus Thomas, S. Harper, 2011, Microcirculation.

Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina

D. Bates, J. Bainbridge, N. Ved, 2017, Clinical science.

Association between VEGF Splice Isoforms and Progression-Free Survival in Metastatic Colorectal Cancer Patients Treated with Bevacizumab

P. Catalano, S. Harper, D. Bates, 2012, Clinical Cancer Research.

VEGF in the lung: a role for novel isoforms

S. Harper, D. Bates, A. Medford, 2010, American journal of physiology. Lung cellular and molecular physiology.

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

Andrew J. Bannister, S. Robson, J. Marioni, 2018, Nature Communications.

Neurotrophin-3 Is a Novel Angiogenic Factor Capable of Therapeutic Neovascularization in a Mouse Model of Limb Ischemia

D. Bates, N. Ieronimakis, M. Reyes, 2010, Arteriosclerosis, thrombosis, and vascular biology.

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro.

P. Kehoe, S. Harper, D. Bates, 2013, The American journal of pathology.

Hyperglycemia Stimulates a Sustained Increase in Hydraulic Conductivity In Vivo without Any Change in Reflection Coefficient

S. Harper, D. Bates, R. Corrall, 2007, Microcirculation.

Cytosolic Ca2+ concentration and rate of increase of the cytosolic Ca2+ concentration in the regulation of vascular permeability in Rana in vivo

D. Bates, C. A. Glass, T. Pocock, 2005, The Journal of physiology.

Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors

D. Bates, O. Sansom, J. Banales, 2020, Nature Communications.

Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression.

Nicholas Beazley-Long, Kevin Gaston, Antonio Orlando, 2015, American journal of cancer research.

Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.

Christine J. Martin, William A. Vousden, M. Gregory, 2011, Chemical science.

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain

D. Bates, L. Donaldson, R. Hulse, 2016, Neurobiology of Disease.

Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor

S. Harper, D. Bates, A. Churchill, 2005, Diabetologia.

Human uremic plasma increases microvascular permeability to water and proteins in vivo.

S. Harper, D. Bates, C. Tomson, 2002, Kidney international.

Vascular endothelial growth factor isoforms differentially protect neurons against neurotoxic events associated with Alzheimer’s disease

J. Morris, K. Morgan, D. Bates, 2023, Frontiers in Molecular Neuroscience.

The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.

Yan Qiu, S. Harper, D. Bates, 2006, Clinical science.

Vascular endothelial growth factor-C (VEGF-C) expression in normal human tissues.

D. Bates, K. Joory, P. Mortimer, 2006, Lymphatic research and biology.

Measurement of Revascularization in the Hind Limb After Experimental Ischemia in Mice.

D. Bates, Maria J C Machado, Sohni R Bhalla, 2022, Methods in molecular biology.

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation

A. Noël, D. Bates, M. Gammons, 2013, Angiogenesis.

Transmission Electron Microscopy of Endothelium.

D. Bates, K. Arkill, C. Neal, 2022, Methods in molecular biology.

Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy

D. Bates, Zheng He, B. Bui, 2020, The Journal of clinical investigation.

Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle

D. Bates, M. Simmons, R. Foster, 2015, Nano Research.

Models of Oxygen Induced Retinopathy in Rodents.

D. Bates, M. Gammons, Melissa V. Gammons, 2016, Methods in molecular biology.

A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties

C. Gooding, Christopher W. J. Smith, S. Harper, 2021, Oncogenesis.

Detection of VEGF-Axxxb Isoforms in Human Tissues

Athina Mavrou, S. Harper, D. Bates, 2013, PloS one.

Therapeutic potential of inhibitory VEGF splice variants.

S. Harper, D. Bates, 2005, Future oncology.

Impaired vascular permeability regulation caused by the VEGF165b splice variant in pre‐eclampsia

S. Harper, D. Bates, P. Soothill, 2011, BJOG : an international journal of obstetrics and gynaecology.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy

G. Damodaran, S. Harper, D. Bates, 2014, Angiogenesis.

S. Harper, D. Bates, C. Paraskeva, 2008, British Journal of Cancer.

Neurotrophin-3 Is a Novel Angiogenic Factor Capable of Therapeutic Neovascularization in a Mouse Model of Limb Ischemia

D. Bates, N. Ieronimakis, M. Reyes, 2010, Arteriosclerosis, thrombosis, and vascular biology.

The anti-angiogenic isoforms of VEGF in health and disease.

S. Harper, D. Bates, S. Oltean, 2009, Biochemical Society transactions.

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

Athina Mavrou, M. Ladomery, S. Harper, 2012, Biochemical Society transactions.

Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina

D. Bates, J. Bainbridge, N. Ved, 2017, Clinical science.

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

S. Harper, D. Bates, N. Ved, 2015, Clinical science.

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

S. Harper, D. Bates, Y. Qiu, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Open Access Research Article Prediction of Melanoma Metastasis by the Shields Index Based on Lymphatic Vessel Density

D. Bates, C. Metcalfe, M. Emmett, 2022 .

PC18 PERITUMOUR LYMPHATIC DENSITY (LD) IN METASTATIC MALIGNANT MELANOMA LIES WITHIN THE RANGE OF SUPERFICIAL DERMAL LD IN NORMAL HUMAN SKIN

D. Bates, K. Joory, P. Mortimer, 2004 .

Lack of active lymphangiogenesis in malignant melanoma despite increased lymphatic density and lymphangiogenic growth factor expression.

D. Bates, P. Mortimer, J. R. Levick, 2004 .

Integrative Physiology/Experimental Medicine Critical Role of Tissue Kallikrein in Vessel Formation and Maturation Implications for Therapeutic Revascularization

D. Bates, P. Quax, L. Barcelos, 2009 .

Glomerular filtration barrier and molecular segregation: guilty as charged?

S. Harper, D. Bates, 2010, Journal of the American Society of Nephrology : JASN.