M. Lindvall

发表

A critical assessment of docking programs and scoring functions.

C. E. Peishoff, G. Warren, C. W. Andrews, 2006, Journal of medicinal chemistry.

2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors.

M. Lindvall, A. Jefferson, Abran Q. Costales, 2014, Bioorganic & medicinal chemistry letters.

Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery

Meir Glick, John D. Coley, Peter S. Kutchukian, 2012, PloS one.

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor.

D. Fabbro, W. Jahnke, G. Rummel, 2015, ACS medicinal chemistry letters.

Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.

M. P. Dillon, M. Lindvall, D. Bussiere, 2017, Journal of medicinal chemistry.

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

M. Lindvall, S. Whitebread, V. Sethuraman, 2018, Bioorganic & medicinal chemistry letters.

An artiﬁcial intelligence approach to pro-actively inspire drug discovery with recommendations.

Steven L. Rohall, M. Lindvall, N. Stiefl, 2020, Journal of medicinal chemistry.

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

M. Lindvall, E. Venetsanakos, Jiong Lan, 2014, Molecular Cancer Research.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.

M. Lindvall, D. Somers, T. Shipley, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent RSK inhibitors.

M. Lindvall, Abran Q. Costales, Michelle Mathur, 2018, Bioorganic & medicinal chemistry letters.

Novel γ-turn mimetics with a reinforced hydrogen bond

M. Lindvall, K. Rissanen, A. Koskinen, 1999 .

Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors.

M. Lindvall, P. Jones, D. Somers, 2008, Bioorganic & medicinal chemistry letters.

Towards the sustainable discovery and development of new antibiotics

H. Petković, I. Gilbert, M. Lindvall, 2021, Nature Reviews Chemistry.

Computer-assisted discovery of novel amino acid derived sulfides for enantioselective epoxidation of aldehydes

M. Lindvall, A. Koskinen, V. Myllymäki, 2001 .

Origins of Stereoselectivity in the Corey-Chaykovsky Reaction. Insights from Quantum Chemistry.

M. Lindvall, A. Koskinen, 1999, The Journal of organic chemistry.

Discovery of Potent and Selective RSK Inhibitors as Biological Probes.

M. Lindvall, Abran Q. Costales, Michelle Mathur, 2015, Journal of medicinal chemistry.

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Audrey Kauffmann, Jianjun Yu, Yumin Dai, 2014, Clinical Cancer Research.

Prediction of pKa Using Machine Learning Methods with Rooted Topological Torsion Fingerprints: Application to Aliphatic Amines

Peter Gedeck, Brian Kelley, Weiping Jia, 2019, J. Chem. Inf. Model..

Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies.

Yumin Dai, Yanchen Zhang, Mika K Lindvall, 2015, Journal of medicinal chemistry.

Large Scale Meta-Analysis of Fragment-Based Screening Campaigns

Anne Mai Wassermann, Meir Glick, S Kirk Wright, 2015, Journal of biomolecular screening.

Regiochemical observations on the lithiation of 1,2,4-trichlorobenzene and reaction with DMF and oxamide electrophiles in THF

M. Lindvall, M. Fuchter, Rajnikant M. Patel, 2003 .

Synthesis and Structure-Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases.

M. Lindvall, Yu Ding, Jiong Lan, 2020, Journal of medicinal chemistry.

Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.

Mika Lindvall, M. Lindvall, Yu Ding, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold.

M. Lindvall, Jiong Lan, Gordana Atallah, 2016, Bioorganic & medicinal chemistry letters.

Size Matters and How You Measure It: A Gram-Negative Antibacterial Example Exceeding Typical Molecular Weight Limits.

M. Lindvall, Fiorella Ruggiu, J. Jansen, 2019, ACS infectious diseases.

Biased Complement Diversity Selection for Effective Exploration of Chemical Space in Hit-Finding Campaigns

Johanna M. Jansen, Charles A. Wartchow, Gianfranco De Pascale, 2019, J. Chem. Inf. Model..

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

M. Lindvall, C. Shafer, Christopher Mcbride, 2011, ACS medicinal chemistry letters.

4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors.

M. Lindvall, C. Shafer, C. Bellamacina, 2008, Bioorganic & medicinal chemistry letters.

The Binding Mode of Calyculin A to Protein Phosphatase-1

M. Lindvall, P. Pihko, A. Koskinen, 1997, The Journal of Biological Chemistry.

Molecular modeling in cysteine protease inhibitor design.

Mika K Lindvall, M. Lindvall, 2002, Current pharmaceutical design.

Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase.

M. Lindvall, R. Jain, Daniel J. Poon, 2015, Bioorganic & medicinal chemistry letters.

Modelling constrained calcitonin gene-related peptide analogues.

M. Lindvall, A. Koskinen, J. Hakala, 1996, Protein Engineering.

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

M. Lindvall, A. Kauffmann, C. Fanton, 2014, Clinical Cancer Research.

Dihydropyrrolidinopyrimidines comme inhibiteurs de kinase

M. Lindvall, Daniel J. Poon, Huw Tanner, 2013 .

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

M. Lindvall, E. Venetsanakos, Jiong Lan, 2014, Molecular Cancer Research.

FOCUS - Development of a Global Communication and Modeling Platform for Applied and Computational Medicinal Chemists

Peter Gedeck, Ruben Abagyan, Maxim Totrov, 2015, J. Chem. Inf. Model..

Novel γ‐Turn Mimetics with a Reinforced Hydrogen Bond.

M. Lindvall, K. Rissanen, A. Koskinen, 2000 .