S. Desiderio

发表

NetPath: a public resource of curated signal transduction pathways

Gary D Bader, C. Sander, P. Khatri, 2010, Genome Biology.

V(D)J recombination and the cell cycle.

S. Desiderio, W. Lin, Weei-Chin Lin, 1995, Immunology today.

Construction of human activity-based phosphorylation networks

J. Qian, D. Zack, A. Gingras, 2013, Molecular systems biology.

RAG Mutations in Human B Cell-Negative SCID

U. Pannicke, K. Schwarz, M. Lieber, 1996, Science.

Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies

S. Desiderio, K. Burns, E. Halper-Stromberg, 2013, BMC Genomics.

Role of Btk in B cell development and signaling.

S. Desiderio, 1997, Current opinion in immunology.

Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein.

S. Desiderio, P. Zwollo, 1994, The Journal of biological chemistry.

Overlapping Signals for Protein Degradation and Nuclear Localization Define a Role for Intrinsic RAG-2 Nuclear Uptake in Dividing Cells

S. Desiderio, A. Ross, M. Vuica, 2003, Molecular and Cellular Biology.

The RAG-2 Inhibitory Domain Gates Accessibility of the V(D)J Recombinase to Chromatin

S. Desiderio, R. Sen, Alyssa Ward, 2018, Molecular and Cellular Biology.

An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation.

S. Desiderio, Yun Liu, Chao Lu, 2015, Cell reports.

Temporal and spatial regulation of V(D)J recombination: interactions of extrinsic factors with the RAG complex.

S. Desiderio, Yun Liu, Li Zhang, 2009, Advances in experimental medicine and biology.

Differential Effects of B Cell Receptor and B Cell Receptor–FcγRIIB1 Engagement on Docking of Csk to GTPase-activating Protein (GAP)-associated p62

S. Desiderio, J. Schneck, M. Vuica, 1997, The Journal of experimental medicine.

IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function

Jamie B. Spangler, S. Zeger, O. Laeyendecker, 2022, JCI insight.

Mimicry of Pre–B Cell Receptor Signaling by Activation of the Tyrosine Kinase Blk

S. Desiderio, A. Ross, T. Tretter, 2003, The Journal of experimental medicine.

The B-Cell-Specific src-Family Kinase Blk Is Dispensable for B-Cell Development and Activation

K. Rajewsky, A. Tarakhovsky, S. Malek, 2000, Molecular and Cellular Biology.

The cell cycle and V(D)J recombination.

S. Desiderio, W. Lin, Zhong Li, 1996, Current topics in microbiology and immunology.

A Genome‐Wide Analysis of the Acute‐Phase Response and Its Regulation by Stat3β

S. Desiderio, Joo-Yeon Yoo, J-Y Yoo, 2003 .

Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development

S. Desiderio, R. Benezra, T. Kadesch, 1991, Molecular and cellular biology.

The transcriptional repressor NKAP is required for the development of iNKT cells

S. Desiderio, S. Hiebert, Puspa Thapa, 2013, Nature Communications.

Cell Cycle-dependent Accumulation in Vivo of Transposition-competent Complexes between Recombination Signal Ends and Full-length RAG Proteins*

S. Desiderio, A. Ross, Hao Jiang, 2004, Journal of Biological Chemistry.

RAG-1 Mutations Associated with B-Cell-Negative SCID Dissociate the Nicking and Transesterification Steps of V(D)J Recombination

S. Desiderio, F. Chang, Wenhui Li, 2001, Molecular and Cellular Biology.

RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution

S. Desiderio, P. Swanson, W. Li, 1997, Molecular and Cellular Biology.

The B cell antigen receptor in B-cell development.

S. Desiderio, 1994, Current opinion in immunology.

Double-stranded cleavage by cell extracts near recombinational signal sequences of immunoglobulin genes

D. Baltimore, S. Desiderio, 1984, Nature.

Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis.

S. Desiderio, D. Huso, Wenyan Lu, 2018, Blood.

NBP, a protein that specifically binds an enhancer of immunoglobulin gene rearrangement: purification and characterization.

S. Desiderio, E. Morzycka-Wroblewska, M. Li, 1989, Genes & development.

An SH3-binding Site Conserved in Bruton's Tyrosine Kinase and Related Tyrosine Kinases Mediates Specific Protein Interactions in Vitro and in Vivo(*)

S. Malek, S. Desiderio, Weiyi Yang, 1995, The Journal of Biological Chemistry.

BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement.

S. Desiderio, W. Yang, Weiyi Yang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk.

K. Zeller, S. Desiderio, F. Kuhajda, 1992, The Journal of biological chemistry.

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle.

S. Desiderio, Zhong Li, Z. Li, 1996, Immunity.

Action of TFII-I Outside the Nucleus as an Inhibitor of Agonist-Induced Calcium Entry

S. Snyder, S. Desiderio, D. V. van Rossum, 2006, Science.

SH2 domains of the protein-tyrosine kinases Blk, Lyn, and Fyn(T) bind distinct sets of phosphoproteins from B lymphocytes.

S. Malek, S. Desiderio, 1993, The Journal of biological chemistry.

Continuing rearrangement of immunoglobulin and T-cell receptor genes in a Ha-ras-transformed lymphoid progenitor cell line.

D. Baltimore, S. Desiderio, J. Pierce, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The Itk/Btk/Tec Family of Protein-Tyrosine Kinases

S. Desiderio, J. Siliciano, 1994 .

The Itk/Btk/Tec family of protein-tyrosine kinases.

S. Desiderio, J. Siliciano, 1994, Chemical immunology.

Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein.

S. Desiderio, T. Kelly, 1981, Journal of molecular biology.

Innate and acquired immunity intersect in a global view of the acute-phase response

Joo-Yeon Yoo, S. Desiderio, Joo-Yeon Yoo, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Vascular Endothelial Growth Factor Receptor-2

S. Desiderio, H. Taylor, S. Danoff, 2005, Journal of Biological Chemistry.

Continuing rearrangement of immu genes in a Ha-ras-transformed lymp (DNA rearrangement/lymphocyte differentiation/retroviral transforr

S. Desiderio, A. Alessandrini, Jacalyn H. PIERCEt, 2016 .

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

S. Desiderio, W. Lin, W. Lin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Identification of Phosphorylation Sites for Bruton's Tyrosine Kinase within the Transcriptional Regulator BAP/TFII-I*

S. Desiderio, A. Egloff, 2001, The Journal of Biological Chemistry.

Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14.

S. Desiderio, C. Kozak, J. Niederhuber, 1991, Genomics.

cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I*

S. Desiderio, Shunhui Zhuang, R. Pilz, 2002, The Journal of Biological Chemistry.

A genome-wide analysis of the acute-phase response and its regulation by Stat3beta.

S. Desiderio, Joo-Yeon Yoo, 2003, Annals of the New York Academy of Sciences.

Specific Ablation of Stat3β Distorts the Pattern of Stat3-Responsive Gene Expression and Impairs Recovery from Endotoxic Shock

Daniel Nathans, Joo-Yeon Yoo, S. Desiderio, 2002, Cell.

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

F. Alt, D. Baltimore, J. Kearney, 1984, Nature.

Phospholipase C-γ Binds Directly to the Na+/H+ Exchanger 3 and Is Required for Calcium Regulation of Exchange Activity*

S. Desiderio, M. Donowitz, Sachin Mohan, 2009, The Journal of Biological Chemistry.

Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.

S. Desiderio, J. Niederhuber, S. Dymecki, 1990, Science.

ADENOVIRUS DNA REPLICATION: POSSIBLE ROLES OF THE COVALENTLY BOUND TERMINAL PROTEIN

S. Desiderio, M. Challberg, T. J. Kelly, 1980 .

p150, a Conserved Nuclear Phosphoprotein That Contains Multiple Tetratricopeptide Repeats and Binds Specifically to SH2 Domains (*)

S. Malek, S. Desiderio, W. Earnshaw, 1996, The Journal of Biological Chemistry.

Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair.

S. Desiderio, J. Lee, Jinhak Lee, 1999, Immunity.

The indoleamine 2,3 dioxygenase pathway drives intratumoral B cell maintenance

S. Desiderio, D. McConkey, L. Xian, 2021, bioRxiv.

Mapping of the gene for the tyrosine kinase Itk to a region of conserved synteny between mouse chromosome 11 and human chromosome 5q.

S. Desiderio, J. Siliciano, C. Kozak, 1994, Genomics.

itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.

S. Desiderio, J. Siliciano, T. Morrow, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The Pax-5 Gene Is Alternatively Spliced during B-cell Development*

S. Desiderio, P. Zwollo, Stephen Desiderio, 1997, The Journal of Biological Chemistry.

Rearrangement of exogenous immunoglobulin VH and DJH gene segments after retroviral transduction into immature lymphoid cell lines

S. Desiderio, K. Wolff, Stephen Desiderio, 1988, The Journal of experimental medicine.

Lymphopoiesis: Transcription factors controlling B-cell development

S. Desiderio, 1995, Current Biology.

Unusual immunoglobulin gene rearrangement leads to replacement of recombinational signal sequences.

S. Desiderio, E. Morzycka-Wroblewska, F. E. Lee, 1988, Science.

Signaling pathways that control V(D)J recombination.

S. Desiderio, J. Lee, 2000, Current topics in microbiology and immunology.

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation.

S. Desiderio, Weei-Chin Lin, W. Lin, 1993, Science.

Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands.

S. Desiderio, M. Challberg, T. Kelly, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

David Baltimore, Frederick W. Alt, F. Alt, 1984, Nature.

Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation

S. Desiderio, A. Alessandrini, 1991, Molecular and cellular biology.

B-cell activation.

S. Desiderio, 1992, Current opinion in immunology.

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.

S. Desiderio, Yun Liu, R. Sen, 2007, Immunity.

FLT3/ITD mice

Jinshui Fan, S. Desiderio, D. Small, 2016 .

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.

Jinshui Fan, S. Desiderio, D. Small, 2011, Blood.

Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.

S. Desiderio, T. Reynolds, Xiaochuan Shan, 2011, Immunity.

Temporal and spatial regulatory functions of the V(D)J recombinase.

S. Desiderio, 2010, Seminars in immunology.

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.

S. Desiderio, A. Ross, Hao Jiang, 2005, Molecular cell.

Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells.

S. Malek, S. Desiderio, L. Samelson, 1993, The Journal of biological chemistry.

Short telomere syndromes cause a primary T cell immunodeficiency

S. Desiderio, J. Siliciano, V. Hanumanthu, 2018, The Journal of clinical investigation.

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

S. Desiderio, M. Borowitz, D. Huso, 2012, Blood.

Binding and allosteric transmission of histone H3 Lys-4 trimethylation to the recombinase RAG-1 are separable functions of the RAG-2 plant homeodomain finger

S. Desiderio, Jack Bettridge, Meiling R May, 2020, The Journal of Biological Chemistry.

Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase.

H. Dintzis, S. Malek, S. Desiderio, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II

S. Desiderio, H. A. Marton, H. Marton, 2008, BMC Molecular Biology.

hCTR9, a Component of Paf1 Complex, Participates in the Transcription of Interleukin 6-responsive Genes through Regulation of STAT3-DNA Interactions*

S. Desiderio, Yongwook Choi, Joo-Yeon Yoo, 2007, Journal of Biological Chemistry.

H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase

A. Pandey, S. Desiderio, C. Na, 2017, Proceedings of the National Academy of Sciences.

53BP1 Is Limiting for NHEJ Repair in ATM-deficient Model Systems That Are Subjected to Oncogenic Stress or Radiation

S. Desiderio, S. Franco, D. Huso, 2013, Molecular Cancer Research.

Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis

S. Desiderio, C. Bingham, Laura C. Cappelli, 2019, Journal of immunology research.

Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.

S. Desiderio, R. Hardy, M. Reth, 2012, Blood.

Synergistic Activity of STAT3 and c-Jun at a Specific Array of DNA Elements in the α2-Macroglobulin Promoter*

S. Desiderio, Wenlan Wang, D. Nathans, 2001, The Journal of Biological Chemistry.

RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex

S. Desiderio, P. Swanson, Stephen Desiderio, 1999, Molecular and Cellular Biology.

Somatic evolution of antibody specificity: setting the clock forward

S. Desiderio, 2000, Nature Immunology.

DNA Damage and Repair 53 BP 1 Is Limiting for NHEJ Repair in ATM-de fi cient Model Systems That Are Subjected to Oncogenic Stress or Radiation

S. Desiderio, S. Franco, D. Huso, 2015 .

A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination

F. Alt, S. Desiderio, E. Oltz, 1993, Molecular and cellular biology.

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

S. Desiderio, P. Swanson, P C Swanson, 1998, Immunity.

Stat3β mitigates development of atherosclerosis in apolipoprotein E-deficient mice

S. Desiderio, W. Baldwin, Jihyun Lee, 2013, Journal of Molecular Medicine.

A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen

Ruhong Zhou, Patrick Cahan, Scheherazade Sadegh-Nasseri, 2019, Cell.

Identification of a DNA binding protein that recognizes the nonamer recombinational signal sequence of immunoglobulin genes.

S. Desiderio, B. Halligan, 1987, Proceedings of the National Academy of Sciences of the United States of America.

A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.

S. Malek, S. Desiderio, 1994, The Journal of biological chemistry.