Lun Yang

发表

Chemical-protein interactome and its application in off-target identification

G. He, A. Jegga, Lun Yang, 2011, Interdisciplinary Sciences: Computational Life Sciences.

Identifying Unexpected Therapeutic Targets via Chemical-Protein Interactome

Leming Shi, Lun Yang, Kejian Wang, 2010, PloS one.

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Kevin C. Dorff, Aaron M. Smalter, Stephen C. Harris, 2010, Nature Biotechnology.

Target Prediction for an Open Access Set of Compounds Active against Mycobacterium tuberculosis

Marc A. Martí-Renom, George Papadatos, Vinod Kumar, 2013, PLoS Comput. Biol..

Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.

Leming Shi, W. Tong, H. Hong, 2015, Combinatorial chemistry & high throughput screening.

Systematic Drug Repositioning Based on Clinical Side-Effects

Pankaj Agarwal, Lun Yang, 2011, PloS one.

Identification of Human Disease Genes from Interactome Network Using Graphlet Interaction

Lun Yang, Dongqing Wei, Zong-Lai Jiang, 2014, PloS one.

Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map

Z. Wen, Leming Shi, Charles Wang, 2011, PloS one.

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

S. Mallal, Leming Shi, Bjoern Peters, 2012, Proceedings of the National Academy of Sciences.

Accurate Quantification of microRNA via Single Strand Displacement Reaction on DNA Origami Motif

Sheng Li, Aiping Zhang, Xiaolu Feng, 2013, PloS one.

Systematic prediction of drug combinations based on clinical side-effects

P. Sanseau, Lun Yang, Ping Zhang, 2014, Scientific Reports.

Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study

Lun Yang, Shufeng Zhou, Zhi-Wei Zhou, 2014, Drug design, development and therapy.

Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells

Lun Yang, Shufeng Zhou, Zhi-Wei Zhou, 2015, Drug design, development and therapy.

Metabolomic Analysis Reveals Metabolic Disturbance in the Cortex and Hippocampus of Subchronic MK-801 Treated Rats

G. He, Lin He, Lun Yang, 2013, PloS one.

Characterization of a novel missense mutation on murine Pax3 through ENU mutagenesis.

Lun Yang, Yue Xiao, Lin He, 2011, Journal of genetics and genomics = Yi chuan xue bao.

DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome

Lin He, Jian Chen, Leming Shi, 2011, Nucleic Acids Res..

Label-free quantitative proteomic analysis reveals dysfunction of complement pathway in peripheral blood of schizophrenia patients: evidence for the immune hypothesis of schizophrenia.

G. He, Lin He, Lun Yang, 2012, Molecular bioSystems.

Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.

Y. Fang, J. Xuan, Lin He, 2011, Journal of proteome research.

Quantitative assessment of the effect of LRRK2 exonic variants on the risk of Parkinson's disease: a meta-analysis.

Lun Yang, Shengying Qin, Lin He, 2012, Parkinsonism & related disorders.

ReCGiP, a database of reproduction candidate genes in pigs based on bibliomics

Qishan Wang, Lun Yang, Jian Chen, 2010, Reproductive biology and endocrinology : RB&E.

A CitationRank algorithm inheriting Google technology designed to highlight genes responsible for serious adverse drug reaction

Lin He, Lun Yang, Langlai Xu, 2009, Bioinform..

Data and text mining A CitationRank algorithm inheriting Google technology designed to highlight genes responsible for serious adverse drug reaction

Lun Yang, Lin He, Langlai Xu, 2009 .

Systematic polymorphism analysis of the CYP2D6 gene in four different geographical Han populations in mainland China.

J. Xie, Lun Yang, Shengying Qin, 2008, Genomics.

Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network

Hongkang Mei, Chaoqun Niu, Christopher D. Green, 2013, PLoS Comput. Biol..

Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China.

J. Xie, G. He, Lun Yang, 2008, Pharmacogenomics.

Exploring Off-Targets and Off-Systems for Adverse Drug Reactions via Chemical-Protein Interactome — Clozapine-Induced Agranulocytosis as a Case Study

Lin He, Jian Chen, Leming Shi, 2011, PLoS Comput. Biol..

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

Lin He, Jian Chen, Lun Yang, 2009, PLoS Comput. Biol..

Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human Liver

Leming Shi, H. Hong, B. Ning, 2012, Journal of drug metabolism & toxicology.

Systematic evaluation of connectivity map for disease indications

Pankaj Agarwal, Lun Yang, Vinod Kumar, 2014, Genome Medicine.

Evaluation of Analytical Methods for Connectivity Map Data

Pankaj Agarwal, Vinod Kumar, Jie Cheng, 2012, Pacific Symposium on Biocomputing.

Systematic screening for polymorphisms within the UGT1A6 gene in three Chinese populations and function prediction through structural modeling.

J. Xuan, Lun Yang, Shengying Qin, 2009, Pharmacogenomics.

Prediction of Drug-Target Interactions for Drug Repositioning Only Based on Genomic Expression Similarity

Lin He, Shufeng Zhou, Can Li, 2013, PLoS Comput. Biol..

Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters

Leming Shi, Jim Kaput, Baitang Ning, 2013, PloS one.

Functional characterization of CYP2D6 novel allelic variants identified in the Chinese Han population.

Lun Yang, Shengying Qin, Lin He, 2016, Pharmacogenomics.

Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients

J. Xuan, Lin He, Lun Yang, 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Drug repositioning for orphan diseases

Cheng Zhu, Anil G. Jegga, Minlu Zhang, 2011, Briefings Bioinform..

DDI-CPI, a server that predicts drug–drug interactions through implementing the chemical–protein interactome

Ping Zhang, Lin He, Hui Huang, 2014, Nucleic Acids Res..

Systematic evaluation of connectivity map for disease indications

Pankaj Agarwal, Pankaj Agarwal, Lun Yang, 2014, Genome Medicine.

Molecular Docking for Prediction and Interpretation of Adverse Drug Reactions.

Jianying Hu, Heng Luo, Lun Yang, 2018, Combinatorial chemistry & high throughput screening.

SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical–protein interactome

Lin He, Jian Chen, Qinghe Xing, 2009, Nucleic Acids Res..

DPDR-CPI, a server that predicts Drug Positioning and Drug Repositioning via Chemical-Protein Interactome

Heng Luo, Ping Zhang, Leming Shi, 2016, Scientific Reports.

Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population

Lun Yang, Shengying Qin, Lin He, 2012, PloS one.

HLADR: a database system for enhancing the discovery of biomarkers for predicting human leukocyte antigen-mediated idiosyncratic adverse drug reactions.

Leming Shi, Qinghe Xing, Heng Luo, 2015, Biomarkers in medicine.

Correction: Prediction of Drug-Target Interactions for Drug Repositioning Only Based on Genomic Expression Similarity

Lun Yang, Kejian Wang, Shengying Qin, 2013, PLoS Computational Biology.

Computational Drug Repositioning: From Data to Therapeutics

P. Sanseau, Pankaj Agarwal, Lun Yang, 2013, Clinical pharmacology and therapeutics.

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Todd H. Stokes, Kevin C. Dorff, Aaron M. Smalter, 2010, Nature Biotechnology.

Drug repositioning for orphan diseases

A. Jegga, Lun Yang, Minlu Zhang, 2011, Briefings Bioinform..