D. Klionsky

发表

The regulation of autophagy – unanswered questions

Yongqiang Chen, D. Klionsky, 2011, Journal of Cell Science.

Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.

D. Klionsky, J. Kim, D J Klionsky, 2000, Annual review of biochemistry.

Autophagy in organelle homeostasis: peroxisome turnover.

Daniel J Klionsky, D. Klionsky, Iryna Monastyrska, 2006, Molecular aspects of medicine.

The machinery of macroautophagy

D. Klionsky, Yuchen Feng, Dingxuan He, 2013, Cell Research.

PHB2/prohibitin 2: An inner membrane mitophagy receptor

D. Klionsky, Vikramjit Lahiri, 2017, Cell Research.

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

Daniel J Klionsky, Paul Hofman, D. Klionsky, 2020, Autophagy.

Methods for Monitoring Autophagy from Yeast to Human

Per O. Seglen, Daniel J. Klionsky, Ana Maria Cuervo, 2007, Autophagy.

Endoplasmic Reticulum Stress Triggers Autophagy*

Daniel J Klionsky, D. Klionsky, U. Nair, 2006, Journal of Biological Chemistry.

Regulation mechanisms and signaling pathways of autophagy.

D. Klionsky, Congcong He, 2009, Annual review of genetics.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

Autophagy fights disease through cellular self-digestion

Daniel J. Klionsky, Ana Maria Cuervo, D. Klionsky, 2008, Nature.

Autophagy as a regulated pathway of cellular degradation.

S. Emr, D. Klionsky, D J Klionsky, 2000, Science.

A work in progress

D. Klionsky, 2009, Autophagy.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

John L Cleveland, Masaaki Komatsu, Katsuhiko Kitamoto, 2008, Autophagy.

Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

D. Klionsky, T. Meyer, W. Heo, 2011, Autophagy.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Autophagy: from phenomenology to molecular understanding in less than a decade

Daniel J. Klionsky, D. Klionsky, 2007, Nature Reviews Molecular Cell Biology.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy

Zhijian Li, D. Klionsky, F. Hughson, 2010, The Journal of cell biology.

The molecular machinery of autophagy: unanswered questions

D. Klionsky, 2005, Journal of Cell Science.

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

D. Klionsky, B. Schulman, T. Fenn, 2012, Nature Structural &Molecular Biology.

Aup1p, a Yeast Mitochondrial Protein Phosphatase Homolog, Is Required for Efficient Stationary Phase Mitophagy and Cell Survival*

Daniel J. Klionsky, D. Klionsky, H. Abeliovich, 2007, Journal of Biological Chemistry.

Autophagy: molecular machinery for self-eating

D. Klionsky, T. Yorimitsu, D J Klionsky, 2005, Cell Death and Differentiation.

Sera from patients with type 2 Diabetes and Neuropathy Induce Autophagy and Colocalization with Mitochondria in SY5Y cells

Daniel J Klionsky, D. Klionsky, T. Yoshimori, 2005, Autophagy.

Mammalian autophagy: core molecular machinery and signaling regulation.

Daniel J Klionsky, D. Klionsky, Zhifen Yang, 2010, Current opinion in cell biology.

Monitoring mitophagy in yeast: The Om45-GFP processing assay

D. Klionsky, D. Kang, Tomotake Kanki, 2009, Autophagy.

A multiple ATG gene knockout strain for yeast two-hybrid analysis

D. Klionsky, U. Nair, Yang Cao, 2009, Autophagy.

Analysis of autophagosome membrane cycling by fluorescence microscopy.

D. Klionsky, J. E. Legakis, 2008, Methods in molecular biology.

In vivo reconstitution of autophagy in Saccharomyces cerevisiae

D. Klionsky, Hui Song, H. Cheong, 2008, The Journal of cell biology.

The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae.

D. Klionsky, U. Nair, H. Cheong, 2007, Molecular biology of the cell.

New insights into autophagy using a multiple knockout strain

D. Klionsky, Yang Cao, 2008, Autophagy.

Atg26 is Not Involved in Autophagy-Related Pathways in Saccharomyces cerevisiae

D. Klionsky, Yang Cao, 2007, Autophagy.

Atg9 Trafficking in Autophagy-Related Pathways

D. Klionsky, Congcong He, 2007, Autophagy.

Monitoring autophagy in yeast: the Pho8Delta60 assay.

D. Klionsky, 2007 .

Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast

D. Klionsky, Congcong He, Iryna Monastyrska, 2006, The Journal of cell biology.

What Can We Learn from Trypanosomes?

D. Klionsky, 2006, Autophagy.

Genetic and Phenotypic Overlap between Autophagy and the Cytoplasm to Vacuole Protein Targeting Pathway*

D. Klionsky, M. Thumm, T. Harding, 1996, The Journal of Biological Chemistry.

Two Distinct Pathways for Targeting Proteins from the Cytoplasm to the Vacuole/Lysosome

D. Klionsky, M. Osumi, Y. Ohsumi, 1997, The Journal of cell biology.

Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway.

D. Klionsky, M. Veenhuis, M. U. Hutchins, 1999, Journal of cell science.

Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways.

Michael D. George, D. Klionsky, N. Mizushima, 2000, Molecular biology of the cell.

Apg13p and Vac8p Are Part of a Complex of Phosphoproteins That Are Required for Cytoplasm to Vacuole Targeting*

Yoshiaki Kamada, Lois S. Weisman, Daniel J. Klionsky, 2000, The Journal of Biological Chemistry.

The Itinerary of a Vesicle Component, Aut7p/Cvt5p, Terminates in the Yeast Vacuole via the Autophagy/Cvt Pathways*

D. Klionsky, J. Kim, S. Scott, 2000, The Journal of Biological Chemistry.

Approaching the Molecular Mechanism of Autophagy

D. Klionsky, P. Stromhaug, Per E. Stromhaug, 2001, Traffic.

Degradation of Lipid Vesicles in the Yeast Vacuole Requires Function of Cvt17, a Putative Lipase*

D. Klionsky, A. Fischer, J. Kim, 2001, The Journal of Biological Chemistry.

Cvt9/Gsa9 Functions in Sequestering Selective Cytosolic Cargo Destined for the Vacuole

D. Klionsky, Y. Ohsumi, M. Baba, 2001, The Journal of cell biology.

Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris.

D. Klionsky, W. Dunn, P. Stromhaug, 2001, Molecular biology of the cell.

Convergence of Multiple Autophagy and Cytoplasm to Vacuole Targeting Components to a Perivacuolar Membrane Compartment Prior tode Novo Vesicle Formation*

D. Klionsky, Wei-Pang Huang, P. Stromhaug, 2002, The Journal of Biological Chemistry.

The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways*

D. Klionsky, J. Shima, Chao-Wen Wang, 2002, The Journal of Biological Chemistry.

Yeast homotypic vacuole fusion requires the Ccz1–Mon1 complex during the tethering/docking stage

D. Klionsky, L. Weisman, Chao-Wen Wang, 2003, The Journal of cell biology.

A unified nomenclature for yeast autophagy-related genes.

Daniel J Klionsky, Yasuyoshi Sakai, Marten Veenhuis, 2003, Developmental cell.

Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae.

Daniel J Klionsky, Fulvio Reggiori, D. Klionsky, 2004, Molecular biology of the cell.

Cargo Proteins Facilitate the Formation of Transport Vesicles in the Cytoplasm to Vacuole Targeting Pathway*

D. Klionsky, T. Shintani, 2004, Journal of Biological Chemistry.

Autophagy in Health and Disease: A Double-Edged Sword

Daniel J. Klionsky, D. Klionsky, T. Shintani, 2004, Science.

Canonical and Noncanonical Autophagy as Potential Targets for COVID-19

Daniel J Klionsky, D. Klionsky, I. Sola, 2020, Cells.

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

D. Klionsky, L. Dini, R. Mohammadinejad, 2018, Autophagy.

Inhibiting autophagy reduces retinal degeneration caused by protein misfolding

D. Klionsky, N. Khan, D. Zacks, 2018, Autophagy.

The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain

D. Klionsky, M. J. Ragusa, Clarence Pascual, 2020, Autophagy.

Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging

D. Klionsky, B. Loos, E. Wong, 2017, Progress in Neurobiology.

The Emerging Roles of Autophagy in Human Diseases

D. Klionsky, Yuchen Lei, 2021, Biomedicines.

Defining the membrane precursor supporting the nucleation of the phagophore

D. Klionsky, Amélie Bernard, Amélie Bernard, 2014, Autophagy.

Autophagy in major human diseases

A. Ballabio, Nektarios Tavernarakis, D. Green, 2021, The EMBO journal.

Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases

D. Klionsky, C. Marquette, R. Hung, 2022, Autophagy.

Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases.

S. Emr, D. Klionsky, L. Banta, 1988, Molecular and cellular biology.

In the autophagy trenches: The early research career of Russell L. Deter

D. Klionsky, R. Deter, 2008, Autophagy.

The Core Molecular Machinery of Autophagosome Formation

D. Klionsky, Meiyan Jin, 2013 .

Self-eating with your fingers

J. Hurley, D. Klionsky, 2012, Cell Research.

Alternative protein sorting pathways.

D. Klionsky, J. Kim, S. Scott, 2000, International review of cytology.

Apg2 Is a Novel Protein Required for the Cytoplasm to Vacuole Targeting, Autophagy, and Pexophagy Pathways*

D. Klionsky, H. Abeliovich, J. Kim, 2001, The Journal of Biological Chemistry.

Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused

D. Klionsky, V. Deretic, E. Eskelinen, 2014, Autophagy.

Phosphatidylinositol 4-Kinases Are Required for Autophagic Membrane Trafficking*

D. Klionsky, U. Nair, Zhifen Yang, 2012, The Journal of Biological Chemistry.

A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy.

D. Klionsky, K. Nakayama, J. Brumell, 2010, Cell host & microbe.

Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins

D. Klionsky, B. Schulman, 2014, Nature Structural &Molecular Biology.

A multifactorial score including autophagy for prognosis and care of COVID-19 patients

D. Klionsky, M. Landi, P. Brest, 2020, Autophagy.

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

Daniel J. Klionsky, Muriel Mari, Fulvio Reggiori, 2010, The Journal of cell biology.

The expanding role of Atg8

D. Klionsky, Wayne D Hawkins, W. D. Hawkins, 2021, Autophagy.

Downregulation of autophagy by Met30-mediated Atg9 ubiquitination

D. Klionsky, J. Dengjel, Yuchen Feng, 2020, Proceedings of the National Academy of Sciences.

Explorer SNARE proteins are required for macroautophagy

D. Klionsky, Xuejun Jiang, U. Nair, 2017 .

The membrane sources of macroautophagy

D. Klionsky, J. Geng, Wei-Lien Yen, 2013 .

Ksp1 Kinase Regulates Autophagy via the Target of Rapamycin Complex 1 (TORC1) Pathway*

D. Klionsky, M. Umekawa, 2012, The Journal of Biological Chemistry.

Atg11: a Rab-dependent, coiled-coil membrane protein that acts as a tether for autophagy.

D. Klionsky, Steven K. Backues, 2012, Autophagy.

A role for Atg8–PE deconjugation in autophagosome biogenesis

D. Klionsky, U. Nair, Zhiping Xie, 2012, Autophagy.

Atg11

D. Klionsky, Steven K. Backues, 2012 .

Phosphatidylinositol-3-Phosphate Clearance Plays a Key Role in Autophagosome Completion

D. Klionsky, J. Helms, Mantong Zhao, 2012, Current Biology.

Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway

D. Klionsky, D. Yaver, R. Cueva, 1992, The Journal of cell biology.

Autophagosomes: biogenesis from scratch?

D. Klionsky, F. Reggiori, 2005, Current opinion in cell biology.

Atg27 is required for autophagy-dependent cycling of Atg9.

D. Klionsky, U. Nair, Wei-Lien Yen, 2006, Molecular biology of the cell.

Atg 27 Is Required for Autophagy-dependent Cycling of Atg 9

D. Klionsky, U. Nair, Wei-Lien Yen, 2007 .

Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research

D. Klionsky, B. Levine, 2016, Proceedings of the National Academy of Sciences.

Autophagy and SQSTM1 on the RHOA(d) again

D. Klionsky, Amine Belaid, P. Brest, 2013, Autophagy.

The Norse god of autophagy

P. Seglen, D. Klionsky, 2010, Autophagy.

Elevating PI3P drives select downstream membrane trafficking pathways

D. Klionsky, L. Weisman, Vikramjit Lahiri, 2020, Molecular biology of the cell.

Clockophagy is a novel selective autophagy process favoring ferroptosis

D. Klionsky, G. Kroemer, M. Lotze, 2019, Science Advances.

Direct quantification of autophagic flux by a single molecule-based probe

D. Klionsky, J. Geng, Jiefei Geng, 2017, Autophagy.

Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration

D. Klionsky, N. Khan, D. Zacks, 2016, Autophagy.

Developing a set of guidelines for your research field: a practical approach

D. Klionsky, 2016, Molecular biology of the cell.

Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency

D. Klionsky, Kailiang Jia, C. Carr, 2014, PLoS genetics.

Protein Transport from the Cytoplasm into the Vacuole

D. Klionsky, 1997, The Journal of Membrane Biology.

Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae.

D. Klionsky, J. Nicaud, A. Sibirny, 2005, Autophagy.

Early Secretory Pathway Gene TRS85 is Required for Selective Macroautophagy of Peroxisomes in Yarrowia lipolytica

D. Klionsky, J. Nicaud, A. Sibirny, 2005 .

Monitoring autophagy in yeast: the Pho8Delta60 assay.

D. Klionsky, 2007, Methods in molecular biology.

How Shall I Eat Thee?

P. Seglen, D. Klionsky, I. J. van der Klei, 2007, Autophagy.

Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?

P. Seglen, D. Rubinsztein, D. Klionsky, 2008, Autophagy.

Autophagy in disease and clinical applications

D. Klionsky, 2009 .

Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos

D. Klionsky, Weibin Zhou, Congcong He, 2009, Autophagy.

Autophagy in mammalian systems, Part B. Preface.

D. Klionsky, 2009, Methods in enzymology.

Autophagy in mammalian systems

D. Klionsky, 2009 .

Indirect estimation of the area density of Atg8 on the phagophore

D. Klionsky, U. Nair, Zhiping Xie, 2009, Autophagy.

Analyzing autophagy in zebrafish

D. Klionsky, Congcong He, 2010, Autophagy.

Artophagy: The art of autophagy—Macroautophagy

D. Klionsky, J. Dice, Daniel J. Klionsky, 2010 .

The autophagosome is overrated!

D. Klionsky, 2011, Autophagy.

Vps34 is a phosphatidylinositol 3-kinase, not a phosphoinositide 3-kinase

D. Klionsky, A. Meijer, 2011, Autophagy.

For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3)

D. Klionsky, 2011, Autophagy.

GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis

D. Klionsky, U. Nair, M. Thumm, 2011, Autophagy.

In the beginning there was babble…

D. Klionsky, E. Bruford, J. Hodgkin, 2012, Autophagy.

Receptor protein complexes are in control of autophagy

D. Klionsky, M. Komatsu, Wei-Pang Huang, 2012, Autophagy.

The role of Atg29 phosphorylation in PAS assembly

Leon H. Chew, D. Klionsky, C. Yip, 2013, Autophagy.

The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy.

D. Klionsky, Kai Mao, Xu Liu, 2013, Developmental cell.

Signalphagy: scheduled signal termination by macroautophagy.

D. Klionsky, Amine Belaid, P. Hofman, 2013, Autophagy.

Estimating the size and number of autophagic bodies by electron microscopy

D. Klionsky, Zhiping Xie, J. Ruan, 2014, Autophagy.

Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast

D. Klionsky, V. Uversky, H. Popelka, 2014, Autophagy.

The progression of peroxisomal degradation through autophagy requires peroxisomal division

D. Klionsky, Yuchen Feng, Kai Mao, 2014, Autophagy.

Autophagy is required for zebrafish caudal fin regeneration

D. Klionsky, T. Vellai, M. Varga, 2013, Cell Death and Differentiation.

Post‐translationally‐modified structures in the autophagy machinery: an integrative perspective

D. Klionsky, H. Popelka, 2015, The FEBS journal.

Rph1 mediates the nutrient-limitation signaling pathway leading to transcriptional activation of autophagy

D. Klionsky, Amélie Bernard, Amélie Bernard, 2015, Autophagy.

A reagent forum

D. Klionsky, 2008 .

Nonclassical Protein Sorting to the Yeast Vacuole*

D. Klionsky, 1998, The Journal of Biological Chemistry.

Dimerization-dependent membrane tethering by Atg23 is essential for yeast autophagy

D. Klionsky, M. J. Ragusa, H. Popelka, 2022, Cell reports.

Podocytes and autophagy: a potential therapeutic target in lupus nephritis

D. Klionsky, Hong Zhang, Xu-jie Zhou, 2019, Autophagy.

An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy

D. Klionsky, Vaibhav Sidarala, Debashish Sahu, 2022, Autophagy.

Analysis of the native conformation of the LIR/AIM motif in the Atg8/LC3/GABARAP-binding proteins

D. Klionsky, H. Popelka, 2015, Autophagy.

Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1

D. Klionsky, B. Schulman, S. Kaiser, 2013, Autophagy.

The proteasome subunit RPN10 functions as a specific receptor for degradation of the 26S proteasome by macroautophagy in Arabidopsis

D. Klionsky, X. Wen, Xin Wen, 2016, Autophagy.

Knockdown of PSMB7 Induces Autophagy in Cardiomyocyte Cultures: Possible Role in Endoplasmic Reticulum Stress

D. Klionsky, L. Tumanovska, V. Dosenko, 2013, Pathobiology.

Cell biology: Regulated self-cannibalism

D. Klionsky, 2004, Nature.

Autophagy-Modulating Drugs in the SARS-CoV-2 War Open Questions for Harnessing

D. Klionsky, P. Brest, J. Benzaquen, 2020 .

Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis

D. Klionsky, G. Kroemer, Jinbao Liu, 2022, Autophagy.

DCN released from ferroptotic cells ignites AGER-dependent immune responses

D. Klionsky, G. Kroemer, Shan Zhu, 2021, Autophagy.

Ion Channels and Transporters in Autophagy

D. Klionsky, D. Tang, R. Kang, 2021, Autophagy.

The protective effect of Hif3a RNA interference and HIF‐prolyl hydroxylase inhibition on cardiomyocytes under anoxia‐reoxygenation

D. Klionsky, V. Dosenko, T. Drevytska, 2018, Life sciences.

Nonclassical protein sorting.

D. Klionsky, 1997, Trends in cell biology.

Gene essentiality of Tubgcp4: dosage effect and autophagy regulation in retinal photoreceptors

D. Klionsky, Hanhua Cheng, R. Zhou, 2019, Autophagy.

Autophagy regulation by RNA alternative splicing and implications in human diseases

D. Klionsky, P. González-Rodríguez, Bertrand Joseph, 2022, Nature Communications.

Autophagic membrane delivery through ATG9

D. Klionsky, Yuchen Feng, 2017, Cell Research.

Autophagy and Immunity

D. Klionsky, Xu Liu, 2014 .

Crohn disease and autophagy

D. Klionsky, 2009, Autophagy.

Intermittent time-restricted feeding promotes longevity through circadian autophagy

D. Klionsky, Zhangyuan Yin, 2022, Autophagy.

Artophagy: The Art of Autophagy-the Cvt pathway

D. Goodsell, D. Klionsky, 2010, Autophagy.

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc – Activity

D. Klionsky, G. Kroemer, M. Lotze, 2018, Current Biology.

Autophagy and Vacuole Homeostasis

D. Klionsky, M. Prescott, D. Mijaljica, 2007 .

Autophagy and Vacuole Homeostasis: A Case for Self-Degradation?

D. Klionsky, M. Prescott, D. Mijaljica, 2007, Autophagy.

Atg11 Directs Autophagosome Cargoes to the PAS Along Actin Cables

D. Klionsky, Iryna Monastyrska, F. Reggiori, 2006, Autophagy.

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

D. Klionsky, G. Kroemer, D. Tang, 2020, Autophagy.

Faculty Opinions recommendation of Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.

D. Klionsky, 2004 .

Current opinions on mitophagy in fungi

D. Klionsky, Xueming Zhu, Xiaohong Liu, 2022, Autophagy.

Autophagy is required for G1/G0 quiescence in response to nitrogen starvation in Saccharomyces cerevisiae

D. Klionsky, B. Tu, Guanghua Xiao, 2014, Autophagy.

Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment.

D. Klionsky, M. Chiong, S. Lavandero, 2022, Trends in molecular medicine.

Autophagy-Dependent Ferroptosis: Machinery and Regulation.

D. Klionsky, G. Kroemer, D. Tang, 2020, Cell chemical biology.

Life and Death Decisions—The Many Faces of Autophagy in Cell Survival and Cell Death

D. Klionsky, Gerasimenko M. Yu., 2022, Biomolecules.

Vorinostat in autophagic cell death: a critical insight into autophagy-mediated, -associated and -dependent cell death for cancer prevention.

D. Klionsky, S. Bhutia, S. Patra, 2021, Drug discovery today.

Tumor heterogeneity in autophagy-dependent ferroptosis

D. Klionsky, D. Tang, R. Kang, 2021, Autophagy.

Ferroptosis: machinery and regulation

D. Klionsky, D. Tang, R. Kang, 2020, Autophagy.

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

D. Klionsky, D. Tang, R. Kang, 2020, Autophagy.

Chloroquine in fighting COVID-19: good, bad, or both?

D. Klionsky, D. Tang, R. Kang, 2020, Autophagy.

ER stress in Cardiometabolic Diseases: from Molecular Mechanisms to Therapeutics.

D. Klionsky, V. Uversky, G. Kroemer, 2021, Endocrine reviews.

ER stress in obesity pathogenesis and management.

J. Tuomilehto, D. Klionsky, G. Lip, 2021, Trends in pharmacological sciences.

Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells

D. Klionsky, D. Tang, Ke-Wei Liu, 2022, Cell Death & Disease.

Ferritinophagy and ferroptosis in the management of metabolic diseases

P. Libby, D. Klionsky, G. Kroemer, 2021, Trends in Endocrinology & Metabolism.

A pioneer in the field of autophagy microscopy

D. Klionsky, A. Kovács, 2013, Autophagy.

A human autophagy interaction network

D. Klionsky, 2012, Autophagy.

Autophagy and neurodegeneration.

D. Klionsky, Congcong He, 2006, ACS chemical biology.

Autophagy is a key factor in maintaining the regenerative capacity of muscle stem cells by promoting quiescence and preventing senescence

D. Klionsky, X. Wen, Xin Wen, 2016, Autophagy.

Activation of autophagy is required for muscle homeostasis during physical exercise

D. Klionsky, U. Nair, Usha Nair, 2011, Autophagy.

Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting

S. Emr, D. Klionsky, L. Banta, 1988, The Journal of cell biology.

Autophagy works out.

D. Klionsky, A. Saltiel, 2012, Cell metabolism.

Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast.

D. Klionsky, K. Morano, 1994, Journal of cell science.

New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16

D. Klionsky, D. Gatica, 2020, Autophagy.

AMPK activates autophagy by phosphorylating ULK1.

D. Klionsky, Kai Mao, 2011, Circulation research.

Looking Back on Two Years of Autophagy

D. Klionsky, 2007 .

Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19

D. Klionsky, Ligen Yu, Boxuan Yu, 2021, Medical Hypotheses.

Autophagosome biogenesis requires SNAREs

D. Klionsky, U. Nair, 2011, Autophagy.

Glycolytic Enzymes Coale sce in G Bodies under Hypoxic Stress Graphical Abstract Highlights

J. Yates, John K. Kim, D. Klionsky, 2022 .

Look people, “Atg” is an abbreviation for “autophagy-related.” That’s it.

D. Klionsky, 2012, Autophagy.

The Yeast Vacuole: A Paradigm for Plant Cell Biologists?

D. Klionsky, T. Noda, Y. Ohsumi, 2018 .

Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information

S. Emr, D. Klionsky, L. Banta, 1988, Molecular and cellular biology.

TMEM164 is a new determinant of autophagy-dependent ferroptosis

D. Klionsky, D. Tang, R. Kang, 2022, Autophagy.

Dhh1 promotes autophagy-related protein translation during nitrogen starvation

D. Klionsky, J. H. Lee, Zhiyuan Yao, 2019, PLoS biology.

Spatially distinct pools of TORC1 balance protein homeostasis

D. Klionsky, Vikramjit Lahiri, 2019, Autophagy.

Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy

D. Klionsky, Congcong He, T. Yorimitsu, 2009, Autophagy.

Bidirectional roles of Dhh1 in regulating autophagy

D. Klionsky, Zhiyuan Yao, Meiyan Jin, 2019, Autophagy.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine

D. Klionsky, Elizabeth Delorme-Axford, 2018, Autophagy.

Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly.

D. Klionsky, C. Woldringh, L. Weisman, 1996, Molecular biology of the cell.

Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy

D. Klionsky, D. Gatica, H. Cheong, 2020, Autophagy.

Transport of proteins to the yeast vacuole: autophagy, cytoplasm-to-vacuole targeting, and role of the vacuole in degradation.

D. Klionsky, S. Teter, 2000, Seminars in cell & developmental biology.

Aminopeptidase I Is Targeted to the Vacuole by a Nonclassical Vesicular Mechanism

D. Klionsky, Y. Ohsumi, M. Baba, 1997, The Journal of cell biology.

Cell Death | Autophagy in Fungi and Mammals

D. Klionsky, J. Guan, Sarah C. Stainbrook, 2021, Encyclopedia of Biological Chemistry III.

The AMPK-SKP2-CARM1 axis links nutrient sensing to transcriptional and epigenetic regulation of autophagy.

D. Klionsky, Ziheng Xu, 2016, Annals of translational medicine.

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy

Hong Wang, D. Klionsky, Fen-Jun Jiang, 2012, Autophagy.

Autophagy gets in on the regulatory act.

D. Klionsky, Steven K. Backues, 2011, Journal of molecular cell biology.

Research Highlight Autophagy gets in on the regulatory act

D. Klionsky, Steven K. Backues, 2010 .

Compartment acidification is required for efficient sorting of proteins to the vacuole in Saccharomyces cerevisiae.

D. Klionsky, N. Nelson, H. Nelson, 1992, The Journal of biological chemistry.

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

D. Klionsky, G. Kroemer, M. Lotze, 2018, Developmental cell.

The emerging mechanisms and functions of microautophagy

D. Klionsky, Liming Wang, Han-Ming Shen, 2022, Nature Reviews Molecular Cell Biology.

Autophagosome formation: tracing the source.

D. Klionsky, Amélie Bernard, 2013, Developmental cell.

The curious case of polyamines: spermidine drives reversal of B cell senescence

D. Klionsky, Shree Padma Metur, 2019, Autophagy.

On the relevance of precision autophagy flux control in vivo – Points of departure for clinical translation

D. Klionsky, J. Hofmeyr, B. Loos, 2020, Autophagy.

Mitochondrial fission facilitates mitophagy in Saccharomyces cerevisiae

D. Klionsky, Kai Mao, 2013, Autophagy.

An Interactive Exercise to Learn Eukaryotic Cell Structure & Organelle Function

D. Klionsky, J. Tomashek, 1999 .

Harpooning the Cvt complex to the phagophore assembly site

D. Klionsky, Iryna Monastyrska, F. Reggiori, 2008, Autophagy.

The Function and Trafficking of Atg 8 during Autophagosome Formation by Zhiping Xie

D. Klionsky, Zhiping Xie, A. Chang, 2008 .

How to live long and prosper: autophagy, mitochondria, and aging.

D. Klionsky, Wei-Lien Yen, 2008, Physiology.

Cargo recognition and degradation by selective autophagy

D. Klionsky, Vikramjit Lahiri, D. Gatica, 2018, Nature Cell Biology.

In vitro reconstitution of cytoplasm to vacuole protein targeting in yeast

D. Klionsky, S. V. Scott, 1995, The Journal of cell biology.

How bacteria can block xenophagy: an insight from Salmonella

D. Klionsky, X. Wen, Xin Wen, 2020, Autophagy.

Asymmetric Inhibition of Ulk2 Causes Left–Right Differences in Habenular Neuropil Formation

Robert W. Taylor, D. Klionsky, C. Moens, 2011, The Journal of Neuroscience.

New insights into MTORC1 amino acid sensing and activation.

D. Klionsky, D. Gatica, 2017, Biotarget.

A “short-cut” response of autophagy to oxidative stress: oxygen-dependent activity of a lysine demethylase guides the activity of ULK1 during hypoxia

D. Klionsky, Ge Yu, 2022, Autophagy.

Skn1and Ipt1negatively regulate autophagy in Saccharomycescerevisiae

Y. Hannun, D. Klionsky, F. Madeo, 2010 .

The necessity of nucleophagic modality

D. Klionsky, D. Mijaljica, Dalibor Mijaljica, 2021, Autophagy.

SnapShot: Selective Autophagy

D. Klionsky, Meiyan Jin, Xu Liu, 2013, Cell.

A genomic screen for yeast mutants defective in mitophagy

D. Klionsky, Tomotake Kanki, Ke Wang, 2010, Autophagy.

Intracellular level of S. cerevisiae Rad51 is regulated via proteolysis in a SUMO- and ubiquitin-dependent manner

D. Klionsky, M. Skoneczny, Adrianna Skoneczna, 2022, bioRxiv.

V1-situated Stalk Subunits of the Yeast Vacuolar Proton-translocating ATPase*

T. Stevens, D. Klionsky, J. Tomashek, 1997, The Journal of Biological Chemistry.

A role for diacylglycerol in antibacterial autophagy

D. Klionsky, J. Brumell, Shahab Shahnazari, 2011, Autophagy.

CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis

D. Klionsky, Vikramjit Lahiri, 2018, Autophagy.

A protein conjugation system essential for autophagy

Michael D. George, D. Klionsky, T. Ishii, 1998, Nature.

Seeking punctuation clarity—that is, the proper use of the hyphen and dashes—for publishing in Autophagy

D. Klionsky, 2016, Autophagy.

A cause for childhood ataxia Genetic studies uncover a mutation in a widely conserved protein as the cause of a neurological disorder in two brothers.

D. Klionsky, Jishu Xu, B. Schulman, 2016 .

A PCR analysis of the ubiquitin-like conjugation systems in macroautophagy

D. Sauer, D. Klionsky, A. Bass, 2011, Autophagy.

Mitochondria removal by autophagy

D. Klionsky, Ke Wang, 2011, Autophagy.

Proteinase protection of prApe1 as a tool to monitor Cvt vesicle/autophagosome biogenesis

D. Klionsky, Wei-Lien Yen, 2012, Autophagy.

Permeases Recycle Amino Acids Resulting from Autophagy

D. Klionsky, Zhifen Yang, 2007, Autophagy.

CCT2, a newly identified aggrephagy receptor in mammals, specifically mediates the autophagic clearance of solid protein aggregates

D. Klionsky, Zhihai Zhang, 2022, Autophagy.

As (and when) you like it: on-demand phospholipid synthesis drives phagophore expansion during autophagy

D. Klionsky, Shree Padma Metur, 2020, Autophagy.

The world’s first (and probably last) autophagy video game

D. Klionsky, Wayne D Hawkins, Emily R Grush, 2022, Autophagy.

Let’s Not Forget about Non-Specific Autophagy

D. Klionsky, 2006, Autophagy.

Neurodegeneration: Good riddance to bad rubbish

D. Klionsky, 2006, Nature.

How Selective is Autophagy?

D. Klionsky, 2006 .

Alternative autophagy, brefeldin A and viral trafficking pathways

D. Klionsky, C. Grose, 2016, Autophagy.

Autophagy in age-related macular degeneration

D. Klionsky, K. Kaarniranta, J. Błasiak, 2022, Autophagy.

Incomplete mitophagy in the mevalonate kinase-deficient Saccharomyces cerevisiae and its relation to the MKD-related autoinflammatory disease in humans.

D. Klionsky, D. Gatica, S. Crovella, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Development by self-digestion: molecular mechanisms and biological functions of autophagy.

Daniel J Klionsky, D. Klionsky, B. Levine, 2004, Developmental cell.

Autophagy in Fungi and Mammals

D. Klionsky, J. Guan, Jiefei Geng, 2004 .

Glucose-Induced Pexophagy in Pichia pastoris

D. Klionsky, 2003 .

Cytoplasm to Vacuole Targeting

D. Klionsky, 2003 .

New regulators of PRKN-independent mitophagy

D. Klionsky, Yuchen Lei, 2021, Autophagy.

The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information

S. Emr, D. Klionsky, D. Bedwell, 1987, Molecular and cellular biology.

HS1BP3 provides a novel mechanism of negative autophagy regulation through membrane lipids

D. Klionsky, Zhangyuan Yin, 2017, Autophagy.

Autophagy/virophagy: a “disposal strategy” to combat COVID-19

D. Klionsky, D. Mijaljica, Dalibor Mijaljica, 2020, Autophagy.

Long-distance autophagy

D. Klionsky, Aileen R. Ariosa, 2015, Autophagy.

Autophagy and p70S6 Kinase

T. P. Neufeld, D. Klionsky, P. Codogno, 2005, Autophagy.

There is more to autophagy than induction

D. Klionsky, A. Nemchenko, 2011, Autophagy.

Mitochondrial abnormalities drive cell death in Wolfram syndrome 2

D. Klionsky, Tomotake Kanki, 2009, Cell Research.

New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways

A. Sureda, D. Klionsky, S. Ghavami, 2022, Cancers.

Autophagy in yeast: a review of the molecular machinery.

D. Klionsky, Wei‐Pang Huang, 2002, Cell structure and function.

A novel role of UBQLNs (ubiquilins) in regulating autophagy, MTOR signaling and v-ATPase function

D. Klionsky, Ying Yang, 2020, Autophagy.

Lysosome signaling in cell survival and programmed cell death for cellular homeostasis

D. Klionsky, S. Patil, S. Bhutia, 2022, Journal of cellular physiology.

Assembly of a functional F1 of the proton-translocating ATPase of Escherichia coli.

D. Klionsky, R. D. Simoni, 1985, The Journal of biological chemistry.

The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore.

D. Klionsky, J. Aris, R. D. Simoni, 1985, The Journal of biological chemistry.

Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain

D. Klionsky, Elizabeth Delorme-Axford, 2018, Autophagy.

Autophagy and gene therapy combine in the treatment of liver disease

D. Klionsky, Debra Thompson, Debra Thompson, 2013, Autophagy.

Erwin Knecht—the intelligent and mad, funny and grumpy man of autophagy

D. Klionsky, E. Knecht, 2021, Autophagy.

SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion

B. Joseph, D. Klionsky, Kathleen Grabert, 2022, Cell Death & Disease.

Allosteric regulation through a switch element in the autophagy E2, Atg3

D. Klionsky, Yumei Zheng, B. Schulman, 2020, Autophagy.

Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity

D. Klionsky, H. Holzer, M. Destruelle, 1995, Yeast.

Identification and characterization of a novel yeast gene: the YGP1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation.

D. Klionsky, H. Holzer, D J Klionsky, 1994, Molecular and cellular biology.

The fungal vacuole: composition, function, and biogenesis.

S. Emr, D. Klionsky, D J Klionsky, 1990, Microbiological reviews.

Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

S. Emr, D. Klionsky, L. Banta, 1988, Molecular and cellular biology.

Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications

D. Klionsky, J. Kim, T. Harding, 1996, Applied and environmental microbiology.

Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress.

J. Yates, John K. Kim, D. Klionsky, 2017, Cell reports.

Vps13 is Required for Efficient Autophagy in Saccharomyces cerevisiae

D. Klionsky, Yuchen Lei, Xin Wen, 2022, Contact (Thousand Oaks (Ventura County, Calif.)).

Melatonin-Based Therapeutics for Atherosclerotic Lesions and Beyond: Focusing on Macrophage Mitophagy.

D. Klionsky, D. Mcclements, D. Richardson, 2022, Pharmacological research.

Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae.

Y. Hannun, D. Klionsky, F. Madeo, 2010, FEMS microbiology letters.

Ferroptosis is a type of autophagy-dependent cell death.

D. Klionsky, G. Kroemer, D. Tang, 2020, Seminars in cancer biology.

Crohn's disease, autophagy, and the Paneth cell.

D. Klionsky, 2009, The New England journal of medicine.

Vacuolar hydrolysis and efflux: current knowledge and unanswered questions

D. Klionsky, Katherine R Parzych, 2018, Autophagy.

Searching for the fountain of autophagy-dependent youth

D. Klionsky, E. Bergamini, 2012, Autophagy.

Moments in autophagy and disease: Past and present.

D. Klionsky, Ying Yang, Xin Wen, 2021, Molecular aspects of medicine.

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?

D. Klionsky, Elizabeth Delorme-Axford, 2020, Autophagy.

Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine

D. Klionsky, S. Muller, J. Bayry, 2020, Autophagy.

Targeting autophagy, oxidative stress, and ER stress for neurodegenerative diseases treatment.

D. Klionsky, S. Ghavami, M. Eshraghi, 2022, Journal of controlled release : official journal of the Controlled Release Society.

An overview of autophagy: morphology, mechanism, and regulation.

D. Klionsky, Katherine R Parzych, 2014, Antioxidants & redox signaling.

A Perspective on the Role of Autophagy in Cancer.

D. Klionsky, Vikramjit Lahiri, Aileen R. Ariosa, 2021, Biochimica et biophysica acta. Molecular basis of disease.

Histone post-translational modifications regulate autophagy flux and outcome

B. Joseph, D. Klionsky, J. Füllgrabe, 2013, Autophagy.

The return of the nucleus: transcriptional and epigenetic control of autophagy

B. Joseph, D. Klionsky, J. Füllgrabe, 2013, Nature Reviews Molecular Cell Biology.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

MoVast2 combined with MoVast1 regulates lipid homeostasis and autophagy in Magnaporthe oryzae

D. Klionsky, Xueming Zhu, F. Lin, 2023, Autophagy.

SNARE Proteins Are Required for Macroautophagy

Xuejun Jiang, Daniel J. Klionsky, Jiefei Geng, 2011, Cell.

A comprehensive glossary of autophagy-related molecules and processes

D. Rubinsztein, D. Klionsky, G. Kroemer, 2010, Autophagy.

An Atlas of the Genetic Variations Linking Dysregulation of Autophagy to Human Diseases: The Missing Environmental Link

E. Gilson, D. Klionsky, C. Marquette, 2020 .

Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy

D. Klionsky, 2014, Autophagy.

The role of autophagy in Parkinson's disease.

D. Klionsky, Mantong Zhao, Kai Mao, 2012, Cold Spring Harbor perspectives in medicine.

Autophagy revisited: A conversation with Christian de Duve

D. Klionsky, 2008, Autophagy.

Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

Yuzhuo Wang, D. Klionsky, F. Crea, 2022, Journal of experimental & clinical cancer research : CR.

Molecular Mechanisms of Autophagy in the Cardiovascular System

D. Klionsky, M. Chiong, D. Gatica, 2015, Circulation research.

Atg22 recycles amino acids to link the degradative and recycling functions of autophagy.

D. Klionsky, U. Nair, Zhifen Yang, 2006, Molecular biology of the cell.

Eaten alive: a history of macroautophagy

D. Klionsky, Zhifen Yang, 2010, Nature Cell Biology.

Autophagosome formation: core machinery and adaptations

D. Klionsky, Zhiping Xie, 2007, Nature Cell Biology.

Autophagy and Human Disease

D. Klionsky, Ju Huang, 2007, Cell cycle.

At a Glance: A History of Autophagy and Cancer.

D. Klionsky, Xin Wen, 2019, Seminars in cancer biology.

Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps

D. Klionsky, H. Abeliovich, W. Dunn, 2000, The Journal of cell biology.

Atg32 is a mitochondrial protein that confers selectivity during mitophagy.

D. Klionsky, M. Baba, Tomotake Kanki, 2009, Developmental cell.

An overview of the molecular mechanism of autophagy.

D. Klionsky, Zhifen Yang, 2009, Current topics in microbiology and immunology.

Atg8 controls phagophore expansion during autophagosome formation.

D. Klionsky, U. Nair, Zhiping Xie, 2008, Molecular biology of the cell.

Membrane Recruitment of Aut7p in the Autophagy and Cytoplasm to Vacuole Targeting Pathways Requires Aut1p, Aut2p, and the Autophagy Conjugation Complex

D. Klionsky, John H. Kim, Wei‐Pang Huang, 2001, The Journal of cell biology.

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy.

D. Klionsky, Yuchen Feng, Zhiyuan Yao, 2015, Trends in cell biology.

Atg41/Icy2 regulates autophagosome formation

D. Klionsky, Zhiyuan Yao, Elizabeth Delorme-Axford, 2015, Autophagy.

A genomic screen for yeast mutants defective in selective mitochondria autophagy.

D. Klionsky, Z. Du, Zhifen Yang, 2009, Molecular biology of the cell.

The Molecular Mechanism of Autophagy

D. Klionsky, Chao-Wen Wang, 2003, Molecular medicine.

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway

D. Klionsky, K. Morano, T. Harding, 1995, The Journal of cell biology.

The molecular mechanism of Atg13 function in autophagy induction: What is hidden behind the data?

D. Klionsky, H. Popelka, 2017, Autophagy.

Transcriptional and post-transcriptional regulation of autophagy in the yeast Saccharomyces cerevisiae

D. Klionsky, Elizabeth Delorme-Axford, 2018, The Journal of Biological Chemistry.

Potential therapeutic applications of autophagy

D. Rubinsztein, D. Klionsky, J. Gestwicki, 2007, Nature Reviews Drug Discovery.

Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency

S. Malek, D. Klionsky, E. Eskelinen, 2022, Autophagy.

The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy

Daniel J Klionsky, Jiefei Geng, D. Klionsky, 2008, EMBO reports.

Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism.

D. Klionsky, Vikramjit Lahiri, Wayne D Hawkins, 2019, Cell metabolism.

Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy

D. Klionsky, D. Gatica, 2019, Current Genetics.

Genetic aberrations in macroautophagy genes leading to diseases.

D. Klionsky, F. Reggiori, Nienke van Beek, 2018, Biochimica et biophysica acta. Molecular cell research.

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

D. Klionsky, Amine Belaid, P. Brest, 2013, Cancer research.

Adaptive immunity at the crossroads of autophagy and metabolism

D. Klionsky, Shree Padma Metur, 2021, Cellular & Molecular Immunology.

Atg23 and Atg27 Act at the Early Stages of Atg9 Trafficking in S. cerevisiae

D. Klionsky, Steven K. Backues, Daniel P Orban, 2015, Traffic.

Roles of the Lipid-binding Motifs of Atg18 and Atg21 in the Cytoplasm to Vacuole Targeting Pathway and Autophagy*

D. Klionsky, U. Nair, Zhiping Xie, 2010, The Journal of Biological Chemistry.

Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy.

D. Klionsky, F. Reggiori, Chao-Wen Wang, 2004, Molecular biology of the cell.

Endoplasmic Reticulum Stress: A New Pathway to Induce Autophagy

D. Klionsky, T. Yorimitsu, Tomohiro Yorimitsu, 2007, Autophagy.

Autophagy and disease: unanswered questions

D. Klionsky, Ying Yang, 2020, Cell Death & Differentiation.

ATG4-family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

D. Klionsky, Vikramjit Lahiri, 2021, Autophagy.

A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade

D. Klionsky, Yumei Zheng, B. Schulman, 2019, Nature Communications.

Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole.

D. Klionsky, Y. Ohsumi, K. Morano, 1996, Proceedings of the National Academy of Sciences of the United States of America.

A new class of lysosomal/vacuolar protein sorting signals.

S. Emr, D. Klionsky, 1990, The Journal of biological chemistry.

Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer

A. Chinnaiyan, D. Klionsky, Xuhong Cao, 2021, Nature Cancer.

The autophagy connection.

D. Klionsky, 2010, Developmental cell.

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

S. Finkbeiner, D. Rubinsztein, D. Klionsky, 2011, Autophagy.

Autophagy and inflammation: A special review issue

D. Klionsky, V. Deretic, 2018, Autophagy.

Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

Yuzhuo Wang, D. Klionsky, F. Crea, 2022, Journal of Experimental & Clinical Cancer Research.

An Autophagy-Independent Role for ATG41 in Sulfur Metabolism During Zinc Deficiency

D. Klionsky, J. Coon, D. Eide, 2018, Genetics.

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex

J. Haber, D. Klionsky, Vinay V. Eapen, 2018, bioRxiv.

Posttranslational modification of autophagy-related proteins in macroautophagy

Xiaofang Sun, Daniel J Klionsky, D. Klionsky, 2015, Autophagy.

Yeast mitophagy: Unanswered questions.

D. Klionsky, Yuxiang J Huang, 2021, Biochimica et biophysica acta. General subjects.

Follicular lymphoma–associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR

M. Kaminski, S. Malek, Shaomeng Wang, 2019, The Journal of clinical investigation.

The molecular mechanism of mitochondria autophagy in yeast

D. Klionsky, Tomotake Kanki, T. Kanki, 2010, Molecular microbiology.

Autophagy in the Eukaryotic Cell

D. Klionsky, F. Reggiori, 2002, Eukaryotic Cell.

Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

S. Mitter, D. Klionsky, M. Boulton, 2015, Autophagy.

The LC3-conjugation machinery specifies cargo loading and secretion of extracellular vesicles

D. Klionsky, Elizabeth Delorme-Axford, 2020, Autophagy.

The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy.

D. Klionsky, P. Williamson, D. Gatica, 2019, Molecular cell.

The Roles of Ubiquitin in Mediating Autophagy

D. Klionsky, H. Popelka, Ying Yang, 2020, Cells.

The Ras/cAMP-dependent Protein Kinase Signaling Pathway Regulates an Early Step of the Autophagy Process in Saccharomyces cerevisiae*

D. Klionsky, F. Reggiori, Y. Budovskaya, 2004, Journal of Biological Chemistry.

Autophagy: The Potential Link between SARS-CoV-2 and Cancer

D. Klionsky, Marek J. Łos, S. Ghavami, 2021, Cancers.

Regulation of macroautophagy in Saccharomyces cerevisiae.

D. Klionsky, Y. Inoue, 2010, Seminars in cell & developmental biology.

Proteolytic processing of Atg32 by the mitochondrial i-AAA protease Yme1 regulates mitophagy

D. Klionsky, Meiyan Jin, Xu Liu, 2013, Autophagy.

The Mechanism and Physiological Function of Macroautophagy

D. Klionsky, P. Codogno, 2013, Journal of Innate Immunity.

On the edge of degradation: Autophagy regulation by RNA decay

D. Klionsky, Elizabeth Delorme-Axford, 2019, Wiley interdisciplinary reviews. RNA.

Autophagy: machinery and regulation

D. Klionsky, Clarence Pascual, Zhangyuan Yin, 2016, Microbial cell.

Rph1/KDM4 Mediates Nutrient-Limitation Signaling that Leads to the Transcriptional Induction of Autophagy

B. Joseph, D. Klionsky, Elizabeth Delorme-Axford, 2015, Current Biology.

Article Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation

John K. Kim, D. Klionsky, Dingxuan He, 2022 .

Upstream open reading frames mediate autophagy-related protein translation

D. Klionsky, D. Tang, Xu Liu, 2022, Autophagy.

Dual role of Atg1 in regulation of autophagy-specific PAS assembly in Saccharomyces cerevisiae

D. Klionsky, Hessun Cheong, 2008, Autophagy.

TRIM8: a double-edged sword in glioblastoma with the power to heal or hurt

D. Klionsky, Hamed Hosseinalizadeh, M. S. Kahrizi, 2023, Cellular & Molecular Biology Letters.

In search of an “autophagomometer”

Daniel J Klionsky, Ana Maria Cuervo, D. Rubinsztein, 2009, Autophagy.

CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells

D. Klionsky, S. Mishra, S. Patil, 2023, Autophagy.

Autophagy in Yeast: Mechanistic Insights and Physiological Function

D. Klionsky, H. Abeliovich, 2001, Microbiology and Molecular Biology Reviews.

Vacuolar import of proteins and organelles from the cytoplasm.

D. Klionsky, Y. Ohsumi, D J Klionsky, 1999, Annual review of cell and developmental biology.

Delivery of proteins and organelles to the vacuole from the cytoplasm.

D. Klionsky, S. V. Scott, 1998, Current opinion in cell biology.

Molecular Mechanisms and Regulation of Specific and Nonspecific Autophagy Pathways in Yeast*

D. Klionsky, U. Nair, Usha Nair, 2005, Journal of Biological Chemistry.

Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway.

D. Klionsky, T. Yorimitsu, Tomohiro Yorimitsu, 2005, Molecular biology of the cell.

Atg17 regulates the magnitude of the autophagic response.

D. Klionsky, F. Reggiori, T. Yorimitsu, 2005, Molecular biology of the cell.

Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.

D. Klionsky, T. Shintani, P. Stromhaug, 2002, Developmental cell.

How to get a folded protein across a membrane.

D. Klionsky, S. Teter, D J Klionsky, 1999, Trends in cell biology.

Multiple roles of the cytoskeleton in autophagy

D. Klionsky, Iryna Monastyrska, F. Reggiori, 2009, Biological reviews of the Cambridge Philosophical Society.

Autophagy: mechanism and physiological relevance 'brewed' from yeast studies.

D. Klionsky, R. Devenish, 2012, Frontiers in bioscience.

Sex differences in autophagy-mediated diseases: toward precision medicine

D. Klionsky, Hanhua Cheng, R. Zhou, 2020, Autophagy.

Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

D. Klionsky, D. Tang, Fanghua Ye, 2022, Autophagy.

Regulation and function of autophagy in pancreatic cancer

D. Klionsky, D. Tang, R. Kang, 2020, Autophagy.

The molecular machinery of autophagy and its role in physiology and disease.

D. Klionsky, 2010, Seminars in cell & developmental biology.

The role of autophagy in the pathogenesis of SARS-CoV-2 infection in different cell types

D. Klionsky, N. Rezaei, M. Farjam, 2021, Autophagy.

Autophagy participates in, well, just about everything

D. Klionsky, 2020, Cell Death & Differentiation.

Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein

D. Klionsky, Yang Cao, 2007, Cell Research.

Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay

Jun Z. Li, G. Juhász, D. Klionsky, 2016, eLife.

Post-transcriptional regulation of ATG1 is a critical node that modulates autophagy during distinct nutrient stresses

D. Klionsky, D. Tang, Xinxin Song, 2021, Autophagy.

Roles for PI(3,5)P2 in nutrient sensing through TORC1

G. Tevzadze, Yui Jin, D. Klionsky, 2014, Molecular biology of the cell.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

A. Gingras, A. Nesvizhskii, D. Klionsky, 2018, Proceedings of the National Academy of Sciences.

Differential translation of the genes encoding the proton-translocating ATPase of Escherichia coli.

D. Klionsky, D. Skalnik, R. D. Simoni, 1986, The Journal of biological chemistry.

Membrane binding and homodimerization of Atg16 via two distinct protein regions is essential for autophagy in yeast.

D. Klionsky, H. Popelka, Kelsie A. Leary, 2021, Journal of molecular biology.

The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41

D. Klionsky, J. Dengjel, D. Gatica, 2019, Autophagy.

The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy

K. Kirkegaard, D. Klionsky, Elizabeth Delorme-Axford, 2018, Autophagy.

Ion channels in the regulation of autophagy

D. Klionsky, N. Prevarskaya, R. Skryma, 2018, Autophagy.

An overview of macroautophagy in yeast.

D. Klionsky, Xin Wen, 2016, Journal of molecular biology.

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

T. Myers, D. Klionsky, G. Uzel, 2015, Nature Cell Biology.

The yeast Saccharomyces cerevisiae: an overview of methods to study autophagy progression.

D. Klionsky, Elizabeth Delorme-Axford, F. Reggiori, 2015, Methods.

Assays for the biochemical and ultrastructural measurement of selective and nonselective types of autophagy in the yeast Saccharomyces cerevisiae.

D. Klionsky, Elizabeth Delorme-Axford, F. Reggiori, 2015, Methods.

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

O. Hermanson, B. Joseph, D. Klionsky, 2013, Nature.

The variability of autophagy and cell death susceptibility

D. Klionsky, B. Loos, A. Engelbrecht, 2013, Autophagy.

Ume6 transcription factor is part of a signaling cascade that regulates autophagy

D. Klionsky, K. Inoki, Mantong Zhao, 2012, Proceedings of the National Academy of Sciences.

Relieving Autophagy and 4EBP1 from Rapamycin Resistance

Daniel J. Klionsky, Beat Nyfeler, Christopher J. Wilson, 2011, Molecular and Cellular Biology.

Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae

D. Klionsky, Mantong Zhao, Tao Xu, 2011, The Journal of cell biology.

The Cvt pathway as a model for selective autophagy

D. Klionsky, Melinda A. Lynch-Day, 2010, FEBS letters.

Determining Atg protein stoichiometry at the phagophore assembly site by fluorescence microscopy

D. Klionsky, Jiefei Geng, 2010, Autophagy.

The quantitative Pho8Delta60 assay of nonspecific autophagy.

D. Klionsky, T. Noda, 2008, Methods in enzymology.

Mitophagy in Yeast Occurs through a Selective Mechanism*

D. Klionsky, Tomotake Kanki, T. Kanki, 2008, Journal of Biological Chemistry.

Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy

D. Klionsky, U. Nair, M. Baba, 2008, The Journal of cell biology.

The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae.

D. Klionsky, Iryna Monastyrska, F. Reggiori, 2005, Molecular biology of the cell.

Atg9 Cycles Between Mitochondria and the Pre-Autophagosomal Structure in Yeasts

D. Klionsky, U. Nair, F. Reggiori, 2005, Autophagy.

The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure.

D. Klionsky, F. Reggiori, P. Stromhaug, 2004, Developmental cell.

BECN1 is a new driver of ferroptosis

D. Klionsky, Shan Zhu, D. Tang, 2018, Autophagy.

Apg9p/Cvt7p Is an Integral Membrane Protein Required for Transport Vesicle Formation in the Cvt and Autophagy Pathways

D. Klionsky, Takeshi Noda, Y. Ohsumi, 2000, The Journal of cell biology.

Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.

Chao Zhang, K. Shokat, D. Klionsky, 2003, Molecular biology of the cell.

Structural basis for extremely strong binding affinity of giant ankyrins to LC3/GABARAP and its application in the inhibition of autophagy

D. Klionsky, H. Popelka, 2018, Autophagy.

Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling

Haichao Wang, D. Klionsky, G. Kroemer, 2020, Nature Microbiology.

Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms

Leon H. Chew, M. Dong, D. Klionsky, 2015, Autophagy.

A pathway of targeted autophagy is induced by DNA damage in budding yeast

J. Haber, M. Schuldiner, Vladimir Denic, 2017, Proceedings of the National Academy of Sciences.

Endoplasmic Reticulum–Mitochondria Contacts Are Required for Pexophagy in Saccharomyces cerevisiae

D. Klionsky, Xu Liu, Xin Wen, 2019, Contact (Thousand Oaks (Ventura County, Calif.)).

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

Daniel J Klionsky, Andrew V Samuelson, Jesse R Llop, 2017, Autophagy.

The regulation of aging: does autophagy underlie longevity?

Tibor Vellai, Daniel J Klionsky, D. Klionsky, 2009, Trends in cell biology.

Toward an understanding of autophagosome-lysosome fusion: The unsuspected role of ATG14

D. Klionsky, Amélie Bernard, 2015, Autophagy.

"Autophagy suite": Atg9 cycling in the cytoplasm to vacuole targeting pathway

D. Klionsky, N. Munakata, 2010, Autophagy.

Positive or negative roles of different cyclin-dependent kinase Pho85-cyclin complexes orchestrate induction of autophagy in Saccharomyces cerevisiae.

D. Klionsky, Zhifen Yang, Wei-Lien Yen, 2010, Molecular cell.

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae.

J. Broach, D. Klionsky, S. Zaman, 2007, Molecular biology of the cell.

Psp2, a novel regulator of autophagy that promotes autophagy-related protein translation

D. Klionsky, K. Karbstein, Haina Huang, 2019, Cell Research.

Protein turnover via autophagy: implications for metabolism.

D. Klionsky, N. Mizushima, 2007, Annual review of nutrition.

The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo

A. Gingras, A. Nesvizhskii, D. Klionsky, 2017, bioRxiv.

Transcriptional regulation of ATG9 by the Pho23-Rpd3 complex modulates the frequency of autophagosome formation

D. Klionsky, Meiyan Jin, 2014, Autophagy.

Autophagic Processes in Yeast: Mechanism, Machinery and Regulation

D. Klionsky, F. Reggiori, 2013, Genetics.

A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation

D. Klionsky, Y. Seo, Shigeki Iwase, 2021, Journal of neurochemistry.

Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli

D. Klionsky, R. D. Simoni, W. S. Brusilow, 1982, Journal of bacteriology.

Vps51 Is Part of the Yeast Vps Fifty-three Tethering Complex Essential for Retrograde Traffic from the Early Endosome and Cvt Vesicle Completion*

Daniel J Klionsky, Fulvio Reggiori, D. Klionsky, 2003, The Journal of Biological Chemistry.

How Cells Deal with the Fluctuating Environment: Autophagy Regulation under Stress in Yeast and Mammalian Systems

D. Klionsky, Yuchen Lei, Zhihai Zhang, 2022, Antioxidants.

Mitochondria autophagy in yeast.

D. Klionsky, K. Okamoto, Tomotake Kanki, 2011, Antioxidants & redox signaling.

The transmembrane domain of acid trehalase mediates ubiquitin-independent multivesicular body pathway sorting.

D. Klionsky, F. Reggiori, Ju Huang, 2007, Molecular biology of the cell.

Atg9 sorting from mitochondria is impaired in early secretion and VFT-complex mutants in Saccharomyces cerevisiae

D. Klionsky, F. Reggiori, 2006, Journal of Cell Science.

Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

D. Klionsky, H. Cai, S. Ferro-Novick, 2010, Proceedings of the National Academy of Sciences.

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways.

D. Klionsky, J. Kim, K. P. Eggerton, 1999, Molecular biology of the cell.

Reciprocal regulatory balance within the CLEC16A-RNF41 mitophagy complex depends on an intrinsically disordered protein region.

D. Klionsky, Vaibhav Sidarala, Debashish Sahu, 2023, The Journal of biological chemistry.

BRD4 is a newly characterized transcriptional regulator that represses autophagy and lysosomal function

D. Klionsky, Xin Wen, 2017, Autophagy.

Regulation of autophagy: Modulation of the size and number of autophagosomes

D. Klionsky, Meiyan Jin, 2014, FEBS letters.

Biochemical methods to monitor autophagy-related processes in yeast.

D. Klionsky, H. Cheong, 2008, Methods in enzymology.

Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction

D. Klionsky, J. Hinshaw, H. Popelka, 2017, Proceedings of the National Academy of Sciences.

Transport of a Large Oligomeric Protein by the Cytoplasm to Vacuole Protein Targeting Pathway

D. Klionsky, M. Oda, John H. Kim, 1997, The Journal of cell biology.

Signaling pathways in mammalian autophagy

D. Klionsky, P. Codogno, A. Meijer, 2003 .

The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion

D. Klionsky, C. Yip, Jotham Austin, 2016, Current Biology.

Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy in Saccharomyces cerevisiae*

D. Klionsky, K. Gomi, T. Shintani, 2011, The Journal of Biological Chemistry.

Self-interaction is critical for Atg9 transport and function at the phagophore assembly site during autophagy.

D. Klionsky, Congcong He, M. Baba, 2008, Molecular biology of the cell.

Arp2 links autophagic machinery with the actin cytoskeleton.

Zhijian Li, D. Klionsky, A. Hoppe, 2008, Molecular biology of the cell.

A Cycling Protein Complex Required for Selective Autophagy

D. Klionsky, Wei-Lien Yen, J. E. Legakis, 2007, Autophagy.

Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration

D. Klionsky, A. Kahana, A. Saera-Vila, 2016, Autophagy.

Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae

D. Klionsky, P. Alizadeh, 1996, FEBS letters.

The role of autophagy in cardiovascular pathology.

D. Klionsky, M. Chiong, D. Gatica, 2021, Cardiovascular research.

Potential function for the Huntingtin protein as a scaffold for selective autophagy

D. Housman, S. Finkbeiner, J. Marsh, 2014, Proceedings of the National Academy of Sciences.

Xenophagy: A battlefield between host and microbe, and a possible avenue for cancer treatment

D. Klionsky, Kai Mao, 2017, Autophagy.

Emerging mechanistic insights of selective autophagy in hepatic diseases

D. Klionsky, Yuko Ito, M. Menon, 2023, Frontiers in Pharmacology.

A separation that’s for the best: coming together at the PAS

D. Klionsky, Wayne D Hawkins, W. D. Hawkins, 2020, Cell Research.

The RB1CC1 Claw-binding motif: a new piece in the puzzle of autophagy regulation

D. Klionsky, H. Popelka, 2022, Autophagy.

Molecular dynamics simulations reveal how the reticulon-homology domain of the autophagy receptor RETREG1/FAM134B remodels membranes for efficient selective reticulophagy

D. Klionsky, H. Popelka, 2020, Autophagy.

Cargo recognition and degradation by selective autophagy

D. Klionsky, Vikramjit Lahiri, D. Gatica, 2018, Nature Cell Biology.

CUET-ting edge research

D. Klionsky, Daniel P Orban, 2014, Autophagy.

Resolution of Subunit Interactions and Cytoplasmic Subcomplexes of the Yeast Vacuolar Proton-translocating ATPase (*)

D. Klionsky, J. Sonnenburg, J. Tomashek, 1996, The Journal of Biological Chemistry.

Vacuolar H+-ATPase: From mammals to yeast and back

D. Klionsky, N. Nelson, 1996, Experientia.

Reconstitution in Vitro of the V1 Complex from the Yeast Vacuolar Proton-translocating ATPase

D. Klionsky, J. Tomashek, B. Garrison, 1997, The Journal of Biological Chemistry.

TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy

D. Klionsky, D. Teis, Felichi Mae Arines, 2019, bioRxiv.

In vivo evidence for the role of the epsilon subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli

D. Klionsky, D J Klionsky, R. D. Simoni, 1984, Journal of bacteriology.

Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I

D. Klionsky, M. Oda, A. Hefner-Gravink, 1996, The Journal of cell biology.

MCOLN3/TRPML3 bridges the regulation of autophagosome biogenesis by PtdIns3P and the calcium channel

D. Klionsky, Yuchen Lei, 2022, Autophagy.

Where is the field of autophagy research heading?

D. Klionsky, J. Debnath, W. T. Jackson, 2023, Autophagy.

Copper-dependent autophagic degradation of GPX4 drives ferroptosis

D. Klionsky, G. Kroemer, Jinbao Liu, 2023, Autophagy.

Autophagic degradation of the circadian clock regulator promotes ferroptosis

D. Klionsky, D. Tang, R. Kang, 2019, Autophagy.

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma

M. Kaminski, S. Malek, Shaomeng Wang, 2016, Clinical Cancer Research.

Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics.

D. Klionsky, V. Uversky, G. Kroemer, 2021, Pharmacology & therapeutics.

A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis

K. Tracey, Haichao Wang, D. Klionsky, 2016, Autophagy.

Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane.

D. Klionsky, D. Fleckenstein, M. Rohde, 1998, Journal of cell science.

Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane.

D. Klionsky, D. Fleckenstein, M. Rohde, 1998, Journal of cell science.

Participation of mitochondrial fission during mitophagy

D. Klionsky, Kai Mao, 2013, Cell cycle.

Autophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathway

Daniel J Klionsky, Saeid Ghavami, D. Klionsky, 2020, Virulence.

Atg32 Is a tag for mitochondria degradation in yeast

D. Klionsky, Tomotake Kanki, T. Kanki, 2009, Autophagy.

A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae

D. Klionsky, M. Mari, Aileen R. Ariosa, 2018, Molecular biology of the cell.

Apoptotic cell death in disease—Current understanding of the NCCD 2023

S. Lipton, A. Ciechanover, T. Luedde, 2023, Cell Death & Differentiation.

Eating the endoplasmic reticulum: quality control by autophagy.

Daniel J Klionsky, D. Klionsky, T. Yorimitsu, 2007, Trends in cell biology.

The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy.

D. Klionsky, M. Mari, F. Reggiori, 2019, Autophagy.

A separation that’s for the best: coming together at the PAS

D. Klionsky, Wayne D Hawkins, 2020, Cell Research.

Deciphering the role of autophagy in heart failure

J. Tuomilehto, D. Klionsky, Jun Ren, 2021 .

A missing piece of the puzzle: Atg11 functions as a scaffold to activate Atg1 for selective autophagy

D. Klionsky, Elizabeth Delorme-Axford, 2015, Autophagy.

Molecular machinery required for autophagy and the cytoplasm to vacuole targeting (Cvt) pathway in S. cerevisiae.

D. Klionsky, W. Khalfan, 2002, Current opinion in cell biology.

Molecular Process and Physiological Significance of Mitophagy

D. Klionsky, Ke Wang, 2014 .

Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.

D. Klionsky, J. Kim, M. U. Hutchins, 2001, Molecular cell.

TEX264 is a major receptor for mammalian reticulophagy

D. Klionsky, Elizabeth Delorme-Axford, H. Popelka, 2019, Autophagy.

UIM-UDS: a new interface between ATG8 and its interactors

D. Klionsky, Yuchen Lei, 2019, Cell Research.

A Systems Biology Approach to Learning Autophagy

D. Klionsky, Anuj Kumar, 2006, Autophagy.

Autophagy core machinery: overcoming spatial barriers in neurons

D. Klionsky, Aileen R. Ariosa, 2016, Journal of Molecular Medicine.

Bidirectional roles of the Ccr4-Not complex in regulating autophagy before and after nitrogen starvation

D. Klionsky, Yuchen Lei, Zhihai Zhang, 2022, Autophagy.

Phosphorylation of Atg9 regulates movement to the phagophore assembly site and the rate of autophagosome formation

D. Klionsky, J. Harper, Yuchen Feng, 2016, Autophagy.

A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy

D. Klionsky, Meiyan Jin, Ziheng Xu, 2015, Autophagy.

SNARE Dance

D. Klionsky, R. Takahashi, Rie Takahashi, 2012, Autophagy.

The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective

D. Klionsky, M. Umekawa, 2012, International journal of cell biology.

Post-Golgi Sec Proteins Are Required for Autophagy in Saccharomyces cerevisiae

D. Klionsky, U. Nair, Kyoko Yasumura-Yorimitsu, 2010, Molecular biology of the cell.

Quantitative regulation of vesicle formation in yeast non-specific autophagy

D. Klionsky, Jiefei Geng, 2008, Autophagy.

Atg23 Is Essential for the Cytoplasm to Vacuole Targeting Pathway and Efficient Autophagy but Not Pexophagy*

D. Klionsky, F. Reggiori, W. Dunn, 2003, Journal of Biological Chemistry.

Vacuolar Localization of Oligomeric α-Mannosidase Requires the Cytoplasm to Vacuole Targeting and Autophagy Pathway Components in Saccharomyces cerevisiae *

D. Klionsky, M. U. Hutchins, Maria U. Hutchins, 2001, The Journal of Biological Chemistry.

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation

Leon H. Chew, D. Klionsky, C. Yip, 2013, Proceedings of the National Academy of Sciences.

Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy

Daniel J. Klionsky, Jiefei Geng, Misuzu Baba, 2008, The Journal of Cell Biology.

Structural characterization of the Saccharomyces cerevisiae autophagy regulatory complex Atg17-Atg31-Atg29

Leon H. Chew, D. Klionsky, C. Yip, 2013, Autophagy.

Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunction

B. Salin, D. Klionsky, S. Manon, 2013, Journal of Cell Science.

Found art: the yeast vacuole

D. Klionsky, S. Hartley, 2019, Autophagy.

Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy*

S. Emr, D. Klionsky, Trey K. Sato, 2002, The Journal of Biological Chemistry.

Skn 1 and Ipt 1 negatively regulateautophagy in Saccharomyces cerevisiae

Y. Hannun, D. Klionsky, F. Madeo, 2010 .

Copper metabolism in cell death and autophagy

D. Klionsky, Jinbao Liu, D. Tang, 2023, Autophagy.

The coordination of V-ATPase and ATG16L1 is part of a common mechanism of non-canonical autophagy

D. Klionsky, Yuchen Lei, 2022, Autophagy.

Did evolution choose Atg11 as the scaffolding platform beyond selective autophagy?

D. Klionsky, Yuxiang J Huang, 2021, Autophagy.

Quantification of Autophagosome Size and Formation Rate by Electron and Fluorescence Microscopy in Baker’s Yeast

D. Klionsky, Steven K. Backues, 2021, Neuromethods.

Conserved and unique features of the fission yeast core Atg1 complex

Leon H. Chew, M. Dong, D. Klionsky, 2017, Autophagy.

One step closer to understanding mammalian macroautophagy initiation: Interplay of 2 HORMA architectures in the ULK1 complex

D. Klionsky, H. Popelka, 2015, Autophagy.

AMPK-dependent phosphorylation of ULK1 induces autophagy.

D. Klionsky, Mantong Zhao, 2011, Cell metabolism.

The phagophore in four dimensions—a study in wood

D. Klionsky, John C Sewell, 2018, Autophagy.

Quiltophagy—autophagy as folk art

D. Klionsky, Barbara M Crumrine, 2015, Autophagy.

Macromusophagy

D. Klionsky, Wendy W-K Lee, 2014 .

Macromusophagy: A solo piano musical representation of macroautophagy.

D. Klionsky, Wendy W-K Lee, 2014, Autophagy.

Detection of Saccharomyces cerevisiae Atg13 by western blot

D. Klionsky, L. Miller-Fleming, H. Cheong, 2014, Autophagy.

Keeping the engine clean

D. Klionsky, M. Campanella, 2013, Autophagy.

MitoPho8Δ60 Assay as a Tool to Quantitatively Measure Mitophagy Activity.

D. Klionsky, Zhiyuan Yao, Xu Liu, 2018, Methods in molecular biology.

Dissecting autophagosome formation: The missing pieces

D. Klionsky, U. Nair, Zhiping Xie, 2008, Autophagy.

When acidic residues do not mimic phosphorylation: high-affinity binding of the reticulophagy receptor TEX264 to LC3/GABARAP

D. Klionsky, H. Popelka, 2022, Autophagy.

Escherichia coli mutants defective in the uncH gene

D. Klionsky, R. Gunsalus, R. D. Simoni, 1983, Journal of bacteriology.

The vacuole versus the lysosome: when size matters.

D. Klionsky, E. Eskelinen, 2014, Autophagy.

Tor-dependent post-transcriptional regulation of autophagy: Implications for cancer therapeutics

T. Myers, D. Klionsky, G. Uzel, 2016, Molecular & cellular oncology.

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity

D. Klionsky, D. Tang, R. Kang, 2018, Autophagy.

Autophagy promotes cell motility by driving focal adhesion turnover

D. Klionsky, Ziheng Xu, 2016, Autophagy.

New thoughts regarding Atg8 and ubiquitination

D. Klionsky, M. Thumm, 2011, Autophagy.

A novel role for a glycolytic pathway kinase in regulating autophagy has implications in cancer therapy

D. Klionsky, Aileen R. Ariosa, 2017, Autophagy.

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

K. Schroder, G. Juhász, D. Rubinsztein, 2018, Autophagy.

Autophagy and disease: unanswered questions

D. Klionsky, Ying Yang, 2020, Cell Death & Differentiation.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

K. Schroder, G. Juhász, D. Rubinsztein, 2019, Autophagy.

Plasmodium protein UIS3 protects the parasite from autophagy clearance

D. Klionsky, Zhiyuan Yao, 2018, Autophagy.

Autophagy regulates DNA repair through SQSTM1/p62

D. Klionsky, Yuchen Feng, 2017, Autophagy.

The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis.

D. Klionsky, M. Zali, A. Yadegar, 2023, Trends in microbiology.

Multiple structural rearrangements mediated by high-plasticity regions in Atg3 are key for efficient conjugation of Atg8 to PE during autophagy

D. Klionsky, H. Popelka, 2021, Autophagy.

Old factors, new players: transcriptional regulation of autophagy

D. Klionsky, Meng-Jie Zhao, Wen-Jie Shu, 2020, Autophagy.

Why do we need to regulate autophagy (and how can we do it)? A cartoon depiction

D. Klionsky, 2018, Autophagy.

TOR-dependent post-transcriptional regulation of autophagy

T. Myers, D. Klionsky, G. Uzel, 2015, Autophagy.

Overview of Autophagy

D. Klionsky, J. E. Legakis, 2006 .

Extracellular SQSTM1 as an inflammatory mediator

D. Klionsky, D. Tang, R. Kang, 2020, Autophagy.

The symphony of autophagy and calcium signaling

D. Klionsky, Zhiyuan Yao, 2015, Autophagy.

Autophagic structures revealed by cryo-electron tomography: new clues about autophagosome biogenesis

D. Klionsky, H. Popelka, 2023, Autophagy.

The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.

D. Klionsky, T. Saigusa, K. Murata, 2023, Molecular cell.

An unconventional pathway for mitochondrial protein degradation

D. Klionsky, Zhiyuan Yao, 2016, Autophagy.

Regulation of autophagy gene expression and its implications in cancer.

D. Klionsky, Yuchen Lei, Zhihai Zhang, 2023, Journal of cell science.

Autophagy under construction: insights from in vitro reconstitution of autophagosome nucleation

D. Klionsky, Shree Padma Metur, 2020, Autophagy.

UIM-UDS: a new interface between ATG8 and its interactors

D. Klionsky, Yuchen Lei, 2019, Cell Research.

The Golgi as a potential membrane source for autophagy

D. Klionsky, Jiefei Geng, 2010, Autophagy.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells

D. Klionsky, S. Ray, M. Chakrabarti, 2016, PloS one.

Points of view: lectures: can't learn with them, can't learn without them.

Harvey F Lodish, Roberto K Rodriguez, Daniel J Klionsky, 2004, Cell biology education.

The human disease gene CLEC16A encodes an intrinsically disordered protein region required for mitochondrial quality control

S. Schnell, D. Klionsky, Vaibhav Sidarala, 2021, bioRxiv.

An atypical BAR domain protein in autophagy

D. Klionsky, H. Popelka, M. Ragusa, 2018, Autophagy.

Blame it on Southern, but it's a western blot

D. Klionsky, 2017, Autophagy.

Mutations in V-ATPase in follicular lymphoma activate autophagic flux creating a targetable dependency

S. Malek, D. Klionsky, Ying Yang, 2022, Autophagy.

Regulation of autophagic lysosome reformation by kinesin 1, clathrin and phosphatidylinositol-4,5-bisphosphate

D. Klionsky, Xu Liu, 2018, Autophagy.

Stepping back from the guidelines: Where do we stand?

D. Klionsky, 2016, Autophagy.

From the urea cycle to autophagy: Alfred J. Meijer

D. Klionsky, A. Meijer, 2011, Autophagy.

Vacuolar ATPase mutants accumulate precursor proteins in a pre-vacuolar compartment.

D. Klionsky, N. Nelson, H. Nelson, 1993, The Journal of biological chemistry.

Mutations in the yeast vacuolar ATPase result in the mislocalization of vacuolar proteins.

D. Klionsky, N. Nelson, H. Nelson, 1992, The Journal of experimental biology.

A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: Complexity and simplicity in crosstalk.

D. Klionsky, G. Sethi, M. Ashrafizadeh, 2023, Pharmacological research.

The Ume6-Sin3-Rpd3 complex regulates ATG8 transcription to control autophagosome size

D. Klionsky, Steven K. Backues, Melinda A. Lynch-Day, 2012, Autophagy.

GPX4 in cell death, autophagy, and disease

D. Klionsky, D. Tang, Yangchun Xie, 2023, Autophagy.

Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence.

D. Klionsky, M. Ashrafizadeh, B. Grimaldi, 2023, Cancer letters.

Double duty of Atg9 self-association in autophagosome biogenesis

D. Klionsky, Congcong He, M. Baba, 2009, Autophagy.

Transcriptional regulation of autophagy and its implications in human disease

D. Klionsky, Yuchen Lei, 2023, Cell Death & Differentiation.

Manipulating Autophagic Degradation in Human Diseases: from Mechanisms to Interventions

D. Klionsky, Q. Zhong, B. Lu, 2022, Life Medicine.

Autophagy is the key to making chronic wounds acute in skin wound healing

D. Klionsky, D. Mijaljica, Fabrizio Spada, 2023, Autophagy.

Dipeptidyl aminopeptidase processing and biosynthesis of alkaline extracellular protease from Yarrowia lipolytica.

D. Klionsky, K. Morano, D. Ogrydziak, 1997, Microbiology.

AutophagosOMES: identification of autophagosomal cargo in CD4+ T cells by proteomics

D. Klionsky, Shree Padma Metur, Faris Jafri, 2022, Autophagy.

Assembly of a functional F0 of the proton-translocating ATPase of Escherichia coli.

D. Klionsky, R. D. Simoni, W. S. Brusilow, 1983, Journal of Biological Chemistry.

A unique hairpin-type tail-anchored SNARE starts to solve a long-time puzzle

D. Klionsky, H. Popelka, Amélie Bernard, 2013, Autophagy.

Aup 1 p , a Yeast Mitochondrial Protein Phosphatase Homolog , Is Required for Efficient Stationary Phase Mitophagy and Cell Survival *

D. Klionsky, H. Abeliovich, G. Winter, 2007 .

The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy

Zhijian Li, D. Klionsky, F. Hughson, 2010, The Journal of cell biology.

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

R A Knight, G Melino, G M Cohen, 2009, Cell Death and Differentiation.

Why do we need autophagy? A cartoon depiction

D. Klionsky, 2018, Autophagy.

NPC-phagy: selective autophagy of the nuclear pore complexes

D. Klionsky, Zhangyuan Yin, 2020, Autophagy.

Crosstalk between autophagy and metabolic regulation of (CAR) T cells: therapeutic implications

D. Klionsky, B. Badie, H. Mirzaei, 2023, Frontiers in immunology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

A. Solovchenko, D. Klionsky, 2020 .

The vacuole vs. the lysosome

D. Klionsky, E. Eskelinen, 2014 .

Stability of Rad51 recombinase and persistence of Rad51 DNA repair foci depends on post-translational modifiers, ubiquitin and SUMO.

D. Klionsky, M. Skoneczny, Adrianna Skoneczna, 2023, Biochimica et biophysica acta. Molecular cell research.

How cells clean house.

D. Klionsky, V. Deretic, 2008, Scientific American.

Finding a ribophagy receptor

D. Klionsky, Meiyan Jin, 2018, Autophagy.

Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase.

S. Emr, D. Klionsky, D. Klionsky, 1989, The EMBO journal.

Constructing Knowledge in the Lecture Hall.

Daniel J. Klionsky, D. Klionsky, 2002 .

Histone post-translational modifications regulate autophagy flux and outcome

B. Joseph, D. Klionsky, J. Füllgrabe, 2013 .

The yeast transcription factor Stb5 acts as a negative regulator of autophagy by modulating cellular metabolism

D. Klionsky, Elizabeth Delorme-Axford, Xin Wen, 2023, Autophagy.

The Pho23-Rpd3 histone deacetylase complex regulates the yeast metabolic transcription factor Stb5.

D. Klionsky, Elizabeth Delorme-Axford, Tabassum Ahmad Tasmi, 2023, microPublication biology.

The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41

D. Klionsky, J. Dengjel, D. Gatica, 2019, Autophagy.

The Pat1-Lsm complex prevents 3′ to 5′ degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy

D. Klionsky, P. Williamson, N. Zhang, 2019, Autophagy.

COMMENTARY AND VIEWS The role of autophagy in the pathogenesis of SARS-CoV-2 infection in different cell types

D. Klionsky, N. Samimi, N. Rezaei, 2021 .

D. Klionsky, U. Nair, M. Thumm, 2011 .

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

D. Klionsky, Marc Diederich, 2012, Autophagy.

The Correct Way to Monitor Autophagy in Higher Eukaryotes

D. Klionsky, 2005, Autophagy.

Autophagy and Immunity

D. Klionsky, Xu Liu, 2014 .

The beneficial role of autophagy in multiple sclerosis: Yes or No?

Ali I. Al-Gareeb, D. Klionsky, G. Batiha, 2023, Autophagy.

Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused

D. Klionsky, V. Deretic, E. Eskelinen, 2014, Autophagy.

Regulation of autophagy: Modulation of the size and number of autophagosomes

D. Klionsky, Meiyan Jin, 2014, FEBS letters.

Multiple roles of the cytoskeleton in autophagy

D. Klionsky, Iryna Monastyrska, F. Reggiori, 2009, Biological reviews of the Cambridge Philosophical Society.

Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps

D. Klionsky, H. Abeliovich, W. Dunn, 2000, The Journal of cell biology.

The lipid basis of cell death and autophagy

D. Klionsky, D. Tang, Minghua Yang, 2023, Autophagy.

Should evidence of an autolysosomal de-acidification defect in Alzheimer and Parkinson diseases call for caution in prescribing chronic PPI and DMARD?

D. Klionsky, P. Brest, B. Mograbi, 2023, Autophagy.

Hitchhiker’s guide through the axon: transport and local translation of Pink1 mRNA support axonal mitophagy

D. Klionsky, Shree Padma Metur, 2022, Autophagy.

Guidelines for the use and interpretation of assays for monitoring autophage

T. P. Neufeld, Thomas J. Begley, H. Coller, 2012 .

MAPKs regulate mitophagy in Saccharomyces cerevisiae

D. Klionsky, Kai Mao, 2011, Autophagy.

The Atg17-Atg31-Atg29 complex and Atg11 regulate autophagosome-vacuole fusion

D. Klionsky, Xu Liu, 2016, Autophagy.

Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy

D. Klionsky, 2014, Autophagy.

2012 Landes Bioscience. Do not distribute. Guidelines for the use and interpretation of assays for monitoring autophagy

Thomas J. Begley, H. Coller, F. Chisari, 2012 .

Autophagy contributes to lysosomal storage disorders

D. Klionsky, Y. Shimada, 2012, Autophagy.

A unified nomenclature for yeast autophagy-related genes.

S. Emr, D. Klionsky, J. Cregg, 2003, Developmental cell.

Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation

John K. Kim, D. Klionsky, Dingxuan He, 2014, Current Biology.

Membraneprotein sorting: biosynthesis, transportand processing ofyeastvacuolar alkaline phosphatase

D. Klionsky, 1989 .

Why just eat in, when you can also eat out?

D. Klionsky, 2013, Autophagy.

Phosphorylation of ULK1 serine 746 dictates ATG5-independent autophagy

D. Klionsky, Xin Wen, 2020, Autophagy.

The Intrinsically Disordered N Terminus in Atg12 from Yeast Is Necessary for the Functional Structure of the Protein

D. Klionsky, Vikramjit Lahiri, Felipe da Veiga Leprevost, 2023, International journal of molecular sciences.

Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy

D. Klionsky, D. Gatica, 2019, Current Genetics.

The role of autophagy in Parkinson's disease.

D. Klionsky, Mantong Zhao, Kai Mao, 2012, Cold Spring Harbor perspectives in medicine.

TP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy

D. Klionsky, Xu Liu, 2015, Autophagy.

Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast

D. Klionsky, Congcong He, Iryna Monastyrska, 2006, The Journal of cell biology.

Bruchpiloting synaptic connections: Egfr in autophagy-mediated neuronal circuit development

D. Klionsky, W. D. Hawkins, Yashveer Chohan, 2023, Autophagy.

Autophagy in yeast: a review of the molecular machinery.

D. Klionsky, Wei‐Pang Huang, 2002, Cell structure and function.

Faculty Opinions recommendation of Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.

D. Klionsky, 2008 .

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex

J. Haber, D. Klionsky, Vinay V. Eapen, 2019, Proceedings of the National Academy of Sciences.

Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast

D. Klionsky, V. Uversky, H. Popelka, 2014, Autophagy.

A guideline on the molecular ecosystem regulating ferroptosis.

H. Bayır, D. Klionsky, F. Greten, 2024, Nature cell biology.

JCB_201309084 1..14

D. Klionsky, S. Dadgar, H. Johnston, 2014 .

Defective autophagy and autophagy activators in myasthenia gravis: a rare entity and unusual scenario

D. Klionsky, S. Albukhaty, G. Sulaiman, 2024, Autophagy.

In vivo reconstitution of autophagy in Saccharomyces cerevisiae

D. Klionsky, Heesun Cheong, Yang Cao, 2022 .

Points of view: lectures: can't learn with them, can't learn without them.

Roberto K Rodriguez, H. Lodish, D. Klionsky, 2004, Cell biology education.

Autophagy-driven regulation of cisplatin response in human cancers: Exploring molecular and cell death dynamics.

D. Klionsky, M. Ashrafizadeh, M. Tambuwala, 2024, Cancer letters.

Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis.

D. Klionsky, T. Billiar, D. Tang, 2023, Immunity.

The Obesity-Autophagy-Cancer Axis: Mechanistic Insights and Therapeutic Perspectives.

D. Klionsky, M. Cordani, Saeid Ghavami, 2024, Seminars in cancer biology.

Integrating bioengineering, super-resolution microscopy and mechanobiology in autophagy research: addendum to the guidelines (4th edition).

D. Klionsky, Cristina Bertocchi, Andrea Ravasio, 2024, Autophagy.

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

D. Klionsky, P. Brest, J. Benzaquen, 2020, Autophagy.

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy

Hong Wang, D. Klionsky, Fen-Jun Jiang, 2012, Autophagy.

Nutrient‐dependent signaling pathways that control autophagy in yeast

D. Klionsky, Shree Padma Metur, 2023, FEBS letters.

Follicular lymphoma-associated mutations in the V-ATPase chaperone Vma21 activate autophagy by dysfunctional V-ATPase assembly.

D. Klionsky, Ying Yang, Zhihai Zhang, 2022, Autophagy reports.

International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis

H. Bayır, D. Klionsky, E. Eftekharpour, 2024, Autophagy.

The Importance of Diversity

Daniel J Klionsky, D. Klionsky, 2007, Autophagy.

Extracellular NCOA4 is a mediator of septic death by activating the AGER-NFKB pathway.

D. Klionsky, D. Tang, Jianxin Jiang, 2024, Autophagy.

Investigating the Interplay between Mitophagy and Diabetic Neuropathy: Uncovering the hidden secrets of the disease pathology.

D. Klionsky, A. Aref, K. Hushmandi, 2024, Pharmacological research.

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation

Leon H. Chew, D. Klionsky, H. Popelka, 2013, Proceedings of the National Academy of Sciences.

Macroautophagy/autophagy promotes resistance to KRASG12D-targeted therapy through glutathione synthesis.

D. Klionsky, D. Tang, Yangchun Xie, 2024, Cancer letters.

Dysregulation of pancreatic β-cell autophagy and the risk of type 2 diabetes.

D. Klionsky, M. S. Jabir, H. Al-kuraishy, 2024, Autophagy.

Clostridioides difficile PCR ribotypes 001 and 084 can trigger autophagy process in human intestinal Caco-2 cells.

D. Klionsky, M. Zali, M. Azimirad, 2023, Microbial pathogenesis.

When an underdog becomes a major player: the role of protein structural disorder in the Atg8 conjugation system.

D. Klionsky, H. Popelka, 2024, Autophagy.

Atg27 is a Second Transmembrane Cycling Protein

D. Klionsky, Wei-Lien Yen, 2007, Autophagy.

The interplay between probiotics and host autophagy: mechanisms of action and emerging insights.

D. Klionsky, M. Zali, Ali Nabavi-Rad, 2024, Autophagy.

Lifeguard Final Exam—Encouraging the Use of Active Learning

Daniel J Klionsky, Elise N Griswold, D. Klionsky, 2015, Journal of Microbiology & Biology Education.

CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival

D. Klionsky, S. Bhutia, S. Patra, 2024, Autophagy.

ATG14 and STX18: gatekeepers of lipid droplet degradation and the implications for disease modulation.

D. Klionsky, Yashveer Chohan, Nathan Shatz, 2024, Autophagy.

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

K. Blomgren, E. Alnemri, D. Klionsky, 2009, Cell Death and Differentiation.