Cunxin Wang

发表

Identification of key residues for protein conformational transition using elastic network model.

J. Su, Xianjin Xu, C. Li, 2011, The Journal of chemical physics.

An Analysis of the Influence of Protein Intrinsic Dynamical Properties on its Thermal Unfolding Behavior

J. Su, Xianjin Xu, C. Li, 2011, Journal of biomolecular structure & dynamics.

A filter enhanced sampling and combinatorial scoring study for protein docking in CAPRI

Shan Chang, Bin Liu, C. Li, 2007, Proteins.

Biologically enhanced sampling geometric docking and backbone flexibility treatment with multiconformational superposition

C. Li, Wei Zu Chen, Cunxin Wang, 2005, Proteins.

Network analysis of protein-protein interaction

Shan Chang, Chunhua Li, Xiong Jiao, 2010 .

Amino acid network and its scoring application in protein-protein docking.

Shan Chang, Xiong Jiao, Cun-xin Wang, 2008, Biophysical chemistry.

A holistic molecular docking approach for predicting protein-protein complex structure

Cunxin Wang, B. Liu, Shan Chang, 2010, Science China Life Sciences.

Prediction of PK-specific phosphorylation site based on information entropy

Cunxin Wang, Minghui Wang, Wei-zu Chen, 2008, Science in China Series C: Life Sciences.

A new computational approach for real protein folding prediction.

Wei Zu Chen, Cunxin Wang, B. Lu, 2003, Protein engineering.

Combined topomer CoMFA and hologram QSAR studies of a series of pyrrole derivatives as potential HIV fusion inhibitors

Cunxin Wang, Chunhua Li, Dan Han, 2018, Medicinal Chemistry Research.

Uncovering the Properties of Energy-Weighted Conformation Space Networks with a Hydrophobic-Hydrophilic Model

Jiguo Su, Cunxin Wang, Wei-zu Chen, 2009, International journal of molecular sciences.

Protein design based on the relative entropy.

Cunxin Wang, Xiong Jiao, Wei-zu Chen, 2006, Physical review. E, Statistical, nonlinear, and soft matter physics.

A generalized approach for protein design based on the relative entropy

Cunxin Wang, Wei-zu Chen, Baohan Wang, 2004 .

Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection.

Xing-Jie Liang, Lee Jia, Cunxin Wang, 2010, Drug discovery today.

Protein–protein docking with binding site patch prediction and network‐based terms enhanced combinatorial scoring

Libin Cao, Xinqi Gong, Shan Chang, 2010, Proteins.

Complex-type-dependent scoring functions in protein-protein docking.

Shan Chang, C. Li, Wei Zu Chen, 2007, Biophysical chemistry.

Scoring Function for the Other-type Protein Complexe

Longzhu Q. Shen, Cunxin Wang, Shan Chang, 2006 .

A soft docking algorithm for predicting the structures of protein-protein complexes.

C. Li, Cunxin Wang, Wei-zu Chen, 2003, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica.

A protein-protein docking algorithm dependent on the type of complexes.

C. Li, Wei Zu Chen, Cunxin Wang, 2003, Protein engineering.

Approach to the unfolding and folding dynamics of add A-riboswitch upon adenine dissociation using a coarse-grained elastic network model.

Yang Zhang, Cunxin Wang, Chunhua Li, 2016, The Journal of chemical physics.

Three-dimensional QSAR analyses of 1,3,4-trisubstituted pyrrolidine-based CCR5 receptor inhibitors.

Cunxin Wang, Wei-zu Chen, Ya Zhuo, 2008, European journal of medicinal chemistry.

Detection of persistent organic pollutants binding modes with androgen receptor ligand binding domain by docking and molecular dynamics

J. Su, Xianjin Xu, Wei Zu Chen, 2013, BMC Structural Biology.

Development of a high-throughput assay for the HIV-1 integrase disintegration reaction

Cunxin Wang, B. Liu, Hong-qiu He, 2010, Science China Life Sciences.

PSPhos: PK-Specific Phosphorylation Site Prediction Using Profile SVM

Cunxin Wang, Chunhua Li, Weizu Chen, 2007 .

The State of the Science: A 5 - Year Review on the Computer - Aided Design for Global Anti - AIDS Drug Development

Cunxin Wang, J. Tan, Chang Liu, 2011 .

Identification of functionally key residues in maltose transporter with an elastic network model-based thermodynamic method

Cunxin Wang, Chunhua Li, J. Tan, 2016 .

Computational Study of Binding Mode for N-substituted Pyrrole Derivatives to HIV-1 gp41*: Computational Study of Binding Mode for N-substituted Pyrrole Derivatives to HIV-1 gp41*

Cunxin Wang, Ming Liu, J. Tan, 2010 .

Activity, Solubility Comparison and Molecular Dynamics Simulation Analysis of Wild Type and F185K Mutant Type HIV-1 Integrase Catalytic Domain*: Activity, Solubility Comparison and Molecular Dynamics Simulation Analysis of Wild Type and F185K Mutant Type HIV-1 Integrase Catalytic Domain*

Cunxin Wang, Jian-ping Hu, Hong-qiu He, 2010 .

Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor.

Cunxin Wang, Hong-qiu He, Liming Hu, 2010, Bioorganic & medicinal chemistry letters.

A novel high-throughput format assay for HIV-1 integrase strand transfer reaction using magnetic beads

Cunxin Wang, Hong-qiu He, Wei-zu Chen, 2008, Acta Pharmacologica Sinica.

Evolving model of amino acid networks.

C. Li, Cunxin Wang, Shan Chang, 2008, Physical review. E, Statistical, nonlinear, and soft matter physics.

Improvement of the relative entropy based protein folding method

Cunxin Wang, Jiguo Su, Li-sheng Qi, 2009 .

Docking dinucleotides to HIV-1 integrase carboxyl-terminal domain to find possible DNA binding sites.

Wei Zu Chen, Cunxin Wang, H. Zhu, 2005, Bioorganic & Medicinal Chemistry Letters.

Design, Synthesis and Anti-HIV Integrase Evaluation of N-(5-Chloro-8-Hydroxy-2-Styrylquinolin-7-yl)Benzenesulfonamide Derivatives

Cunxin Wang, Hong-qiu He, J. Tan, 2010, Molecules.

Study on the inhibitory mechanism and binding mode of the hydroxycoumarin compound NSC158393 to HIV‐1 integrase by molecular modeling

Wei Zu Chen, Cunxin Wang, Ming Liu, 2009, Biopolymers.

Synthesis of 6-sulfamoyl-4-oxoquinoline-3-carboxylic acid derivatives as integrase antagonists with anti-HIV activity

Cunxin Wang, Hong He, Chengchu Zeng, 2009 .

The interactions and recognition of cyclic peptide mimetics of Tat with HIV-1 TAR RNA: a molecular dynamics simulation study

J. Su, Xianjin Xu, C. Li, 2013, Journal of biomolecular structure & dynamics.

Molecular dynamics simulations of the gramicidin A-dimyristoylphosphatidylcholine system with an ion in the channel pore region

Wei Zu Chen, Cunxin Wang, Cun Xin Wang, 2000, European Biophysics Journal.

Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies.

Cunxin Wang, Wei-zu Chen, J. Tan, 2004, Acta pharmacologica Sinica.

Molecular dynamics simulation of the transmembrane subunit of BtuCD in the lipid bilayer

Cunxin Wang, Ming Liu, Weizu Chen, 2010, Science China Life Sciences.

A combinatorial scoring function for protein–RNA docking

Lin Lu, Yue Zhang, Zhao Zhang, 2017, Proteins.

Community-wide assessment of protein-interface modeling suggests improvements to design methodology.

Kengo Kinoshita, Haruki Nakamura, Genki Terashi, 2011, Journal of molecular biology.

A fast empirical approach to binding free energy calculations based on protein interface information.

Wei Zu Chen, Cunxin Wang, Xiao Hui Ma, 2002, Protein engineering.

A new residue‐nucleotide propensity potential with structural information considered for discriminating protein‐RNA docking decoys

J. Su, Cunxin Wang, Cun Xin Wang, 2012, Proteins.

An efficient perturbation method to predict the functionally key sites of glutamine binding protein

Jianjun Tan, Xiaoyi Zhang, Chunhua Li, 2017, Comput. Biol. Chem..

Molecular Dynamics Simulation of HIV‐1 Integrase Dimer Complexed with Viral DNA

Cunxin Wang, Jianping Hu, 2010 .

Study on the molecular mechanism of inhibiting HIV-1 integrase by EBR28 peptide via molecular modeling approach.

J. Su, Wei Zu Chen, Cunxin Wang, 2008, Biophysical chemistry.

An Analysis of Protein Conservation Residues Network

C. Li, Cunxin Wang, Shan Chang, 2007, 2007 1st International Conference on Bioinformatics and Biomedical Engineering.

Investigating interactions between HIV-1 gp41 and inhibitors by molecular dynamics simulation and MM–PBSA/GBSA calculations

Jian Jun Tan, Wei Zu Chen, Cunxin Wang, 2006 .

A novel back-door pathway for glutamine release from GlnBP revealed by steered molecular dynamics simulation

Wei Zu Chen, Cunxin Wang, T. Sun, 2009 .

Insight into the Inhibitory Mechanism and Binding Mode Between D77 and HIV-1 Integrase by Molecular Modeling Methods

Wei Zu Chen, Cunxin Wang, Ming Liu, 2011, Journal of biomolecular structure & dynamics.

High-throughput real-time assay based on molecular beacons for HIV-1 integrase 3′-processing reaction

Cunxin Wang, Hong-qiu He, Wei-zu Chen, 2007, Acta Pharmacologica Sinica.

Two Receptor Based Pharmacophore Models for HIV-1 Integrase DKA Inhibitors

Cunxin Wang, Xiaoyi Zhang, Kun Zeng, 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

Pharmacophore Model Generation Based on Pyrrolidine- and Butane-derived CCR5 Antagonists

Cunxin Wang, R. Kong, Liming Hu, 2007 .

Identification of functionally key residues in AMPA receptor with a thermodynamic method.

J. Su, Xianjin Xu, Wei Zu Chen, 2013, The journal of physical chemistry. B.

Study on the mechanism of the BtuF periplasmic-binding protein for vitamin B12.

Cunxin Wang, Ming Liu, Ming Liu, 2008, Biophysical chemistry.

Analysis of domain movements in glutamine-binding protein with simple models.

J. Su, Wei Zu Chen, Cunxin Wang, 2007, Biophysical journal.

Allosteric transitions of the maltose transporter studied by an elastic network model

J. Su, Cunxin Wang, B. Liu, 2014, Biopolymers.

Prediction of the binding mode between BMS-378806 and HIV-1 gp120 by docking and molecular dynamics simulation.

Wei Zu Chen, Cunxin Wang, Xiao Hui Ma, 2006, Biochimica et biophysica acta.

Structure–activity relationship and binding mode studies for a series of diketo-acids as HIV integrase inhibitors by 3D-QSAR, molecular docking and molecular dynamics simulations

Cunxin Wang, Dan Han, J. Tan, 2016 .

Protein unfolding behavior studied by elastic network model.

J. Su, Wei Zu Chen, Cunxin Wang, 2008, Biophysical journal.

Molecular Dynamics Studies of the Inhibitor C34 Binding to the Wild-Type and Mutant HIV-1 gp41: Inhibitory and Drug Resistant Mechanism

Cunxin Wang, Chunhua Li, J. Tan, 2014, PloS one.

Molecular Dynamics Simulation of HIV-1 gp41 and the N554D/S649A Double Mutation for Drug Resistance to Enfuvirtide

Wei Zu Chen, Cunxin Wang, J. Tan, 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

Molecular dynamics simulations of the bacterial periplasmic heme binding proteins ShuT and PhuT.

Ren Kong, Jian Jun Tan, J. Su, 2008, Biophysical chemistry.

Analysis of the Interactions between the N-Terminal Peptide of gp41 and T20 Using Molecular Dynamics and Free Energy Calculations

Wei Zu Chen, Cunxin Wang, J. Tan, 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

Role of electrostatic interactions for the stability and folding behavior of cold shock protein

J. Su, Wei Zu Chen, Cunxin Wang, 2010, Proteins.

Study on the Resistance and the Binding Mode of HIV-1 Integrase to NSC158393

Cunxin Wang, Ming Liu, Wei-zu Chen, 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

A soft docking algorithm for predicting the structure of antibody‐antigen complexes

Wei Zu Chen, Cunxin Wang, Chun Hua Li, 2003, Proteins: Structure, Function, and Bioinformatics.

Construction and application of the weighted amino acid network based on energy.

Shan Chang, Xiong Jiao, C. Li, 2007, Physical review. E, Statistical, nonlinear, and soft matter physics.

Study on the mechanism of the BtuF periplasmic-binding protein for vitamin B12.

Cunxin Wang, Ming Liu, Weizu Chen, 2008, Biophysical chemistry.

Thermal Stability and Unfolding Pathways of Sso7d and its Mutant F31A: Insight from Molecular Dynamics Simulation

Xianjin Xu, Cunxin Wang, Jiguo Su, 2011, Journal of biomolecular structure & dynamics.