K. Seyb

发表

Cytoskeletal integrity as a drug target.

M. Michaelis, K. Seyb, S. Ansar, 2005, Current Alzheimer research.

Enzymatic Characterization of ER Stress-Dependent Kinase, PERK, and Development of a High-Throughput Assay for Identification of PERK Inhibitors

K. Seyb, M. Glicksman, S. Ray, 2014, Journal of biomolecular screening.

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

P. Greengard, A. Nairn, K. Seyb, 2014, PLoS biology.

High-Throughput Assay for Identification of PERK Inhibitors Enzymatic Characterization of ER Stress-Dependent Kinase , PERK , and Development of a-Jul

K. Seyb, M. Glicksman, S. Ray, 2014 .

Identification of Translational Activators of Glial Glutamate Transporter EAAT2 through Cell-Based High-Throughput Screening

K. Seyb, M. Glicksman, M. Zhu, 2010, Journal of biomolecular screening.

Development of a Mechanism-based HTS Assay for Leucine Rich Repeat Kinase2—Discovery of LRRK2 Inhibitors

K. Seyb, M. Glicksman, Min Liu, 2011 .

Development of a mechanism-based high-throughput screen assay for leucine-rich repeat kinase 2--discovery of LRRK2 inhibitors.

K. Seyb, M. Glicksman, Min Liu, 2010, Analytical biochemistry.

Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design.

K. Seyb, D. Johns, P. Orth, 2020, Journal of medicinal chemistry.

A High-Throughput Screening Method for Small-Molecule Inhibitors of the Aberrant Mutant SOD1 and Dynein Complex Interaction

K. Seyb, M. Glicksman, Xiaohu Tang, 2012, Journal of biomolecular screening.

Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis

K. Seyb, I. Gunnarsson, M. Pickering, 2019, Kidney International.

Inhibition of large T antigen ATPase activity as a potential strategy to develop anti-polyomavirus JC drugs.

K. Seyb, M. Glicksman, M. Huang, 2014, Antiviral research.

Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation

Charles P. Lin, Kelvin S. Ng, J. Karp, 2016, Scientific Reports.

Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization.

K. Seyb, M. Glicksman, J. Concannon, 2012, American journal of neurodegenerative disease.

Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis

K. Seyb, M. Glicksman, C. Combs, 2015, PloS one.

β-amyloid and endoplasmic reticulum stress reponses in primary neurons

M. Michaelis, K. Seyb, S. Ansar, 2007, Journal of Molecular Neuroscience.

beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton.

M. Michaelis, K. Seyb, S. Ansar, 2006, Journal of molecular neuroscience : MN.

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.

K. Seyb, M. Glicksman, Yuchen Lin, 2014, The Journal of clinical investigation.

Preclinical Evaluation of RA101495, a Potent Cyclic Peptide Inhibitor of C5 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria

K. Seyb, S. DeMarco, V. Rajagopal, 2015 .

Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis

K. Seyb, I. Gunnarsson, M. Pickering, 2019, Kidney international.

β-Amyloid-Induced Neurodegeneration and Protection by Structurally Diverse Microtubule-Stabilizing Agents

R. Himes, M. Michaelis, K. Seyb, 2005, Journal of Pharmacology and Experimental Therapeutics.

Development of RA101348, a Potent Cyclic Peptide Inhibitor of C5 for Complement-Mediated Diseases

K. Seyb, A. Ricardo, Sylvia Tobé, 2014 .

p35/Cyclin-dependent kinase 5 is required for protection against β-amyloid-induced cell death but not tau phosphorylation by ceramide

R. Dobrowsky, M. Michaelis, K. Seyb, 2007, Journal of Molecular Neuroscience.

Identification of Small Molecule Inhibitors of β-Amyloid Cytotoxicity through a Cell-Based High-Throughput Screening Platform

Marcie A. Glicksman, M. Michaelis, K. Seyb, 2008, Journal of biomolecular screening.

Identification of Translational Activators of Glial Glutamate Transporter EAAT2 through Cell-Based High-Throughput Screening

K. Seyb, M. Glicksman, M. Zhu, 2010, Journal of biomolecular screening.

Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors.

K. Seyb, M. Glicksman, L. Qiao, 2009, Bioorganic & medicinal chemistry letters.