B. Ravikumar

发表

Regulation of mammalian autophagy in physiology and pathophysiology.

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2010, Physiological reviews.

Rapamycin alleviates toxicity of different aggregate-prone proteins.

D. Rubinsztein, B. Ravikumar, F. Menzies, 2006, Human molecular genetics.

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2010, The Journal of cell biology.

Plasma membrane contributes to the formation of pre-autophagosomal structures

D. Rubinsztein, B. Ravikumar, K. Moreau, 2010, Nature Cell Biology.

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Francesco Scaravilli, Douglas F Easton, Shouqing Luo, 2004, Nature Genetics.

Role of autophagy in the clearance of mutant huntingtin: a step towards therapy?

D. Rubinsztein, B. Ravikumar, 2006, Molecular aspects of medicine.

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2009, Cell Death and Differentiation.

Mammalian macroautophagy at a glance

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2009, Journal of Cell Science.

Plasma membrane helps autophagosomes grow

D. Rubinsztein, B. Ravikumar, K. Moreau, 2010, Autophagy.

Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2009, Methods in enzymology.

Plasma membrane contributes to the formation of pre-autophagosomal structures

D. Rubinsztein, B. Ravikumar, K. Moreau, 2010, Nature Cell Biology.

Can autophagy protect against neurodegeneration caused by aggregate-prone proteins?

D. Rubinsztein, B. Ravikumar, 2004, Neuroreport.

α-Synuclein impairs macroautophagy: implications for Parkinson's disease

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2010 .

Protective Roles for Induction of Autophagy in Multiple Proteinopathies

D. Rubinsztein, B. Ravikumar, F. Menzies, 2006, Autophagy.

Dyneins, Autophagy, Aggregation and Neurodegeneration

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2005, Autophagy.

Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.

Caitlin E. Hamilton, B. Ravikumar, W. Amberg, 2022, European journal of pharmacology.

Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis

B. Ravikumar, J. Oudinet, D. Crawford, 2016, Neuropharmacology.

α-Synuclein Is Degraded by Both Autophagy and the Proteasome*

Jeremy N. Skepper, Julie L. Webb, D. Rubinsztein, 2003, Journal of Biological Chemistry.

Autophagosome Precursor Maturation Requires Homotypic Fusion

D. Rubinsztein, B. Ravikumar, K. Moreau, 2011, Cell.

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D

D. Rubinsztein, B. Ravikumar, K. Moreau, 2012, The Journal of cell biology.

IGF-1 receptor antagonism inhibits autophagy

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2013, Human molecular genetics.

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Kara H. Woo, Cory C. Funk, Kelsey S. Montgomery, 2020, Scientific Data.

Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2006, Current topics in developmental biology.

Arrayed CRISPR reveals genetic regulators of tau aggregation, autophagy and mitochondria in Alzheimer’s disease model

B. Ravikumar, H. Xi, E. Karran, 2021, Scientific Reports.

Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair

N. Heintz, D. Rubinsztein, B. Ravikumar, 2005, Autophagy.

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.

Rainer Duden, D. Rubinsztein, B. Ravikumar, 2002, Human molecular genetics.

In search of an “autophagomometer”

Daniel J Klionsky, Ana Maria Cuervo, D. Rubinsztein, 2009, Autophagy.

Dynein mutations impair autophagic clearance of aggregate-prone proteins

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2005, Nature Genetics.

Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy

D. Rubinsztein, B. Ravikumar, F. Menzies, 2015, Nature Communications.

Palmitoylation of huntingtin by HIP14is essential for its trafficking and function

Lu Gan, Asher Mullard, Catherine M Cowan, 2006, Nature Neuroscience.

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.

D. Rubinsztein, B. Ravikumar, David C Rubinsztein, 2004, The international journal of biochemistry & cell biology.

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2008, Journal of Cell Science.

The roles of the ubiquitin-proteasome and autophagy–lysosome pathways in Huntington's disease and related conditions

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2003, Clinical Neuroscience Research.

Rapamycin pre-treatment protects against apoptosis.

D. Rubinsztein, B. Ravikumar, C. Vacher, 2006, Human molecular genetics.

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy.

D. Rubinsztein, B. Ravikumar, Kikuya Kato, 2003, Human molecular genetics.

Clearance of mutant aggregate-prone proteins by autophagy.

D. Rubinsztein, B. Ravikumar, S. Sarkar, 2008, Methods in molecular biology.

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

Steve D. M. Brown, D. Rubinsztein, B. Ravikumar, 2010, The Journal of cell biology.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

D. Rubinsztein, B. Ravikumar, J. Davies, 2022 .

Guidelines for the use and interpretation of assays for monitoring autophage

T. P. Neufeld, Thomas J. Begley, H. Coller, 2012 .