H. Gendelman

H. Gendelman, S. Swindells, J. Bellanti, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Interferon alpha (IFN)-macrophage interactions in human immunodeficiency virus (HIV) infection: role of IFN in the tempo and progression of HIV disease.

H. Gendelman, M. Meltzer, D. Skillman, 1992, International reviews of immunology.

Interferons in the persistence, pathogenesis, and treatment of HIV infection.

H. Gendelman, M. Meltzer, M. L. Francis, 1992, AIDS research and human retroviruses.

The Promise of Long-Acting Antiretroviral Therapies: From Need to Manufacture.

H. Gendelman, J. McMillan, Aditya N Bade, 2019, Trends in microbiology.

CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

H. Gendelman, S. Dewhurst, C. Gebhart, 2010, The Journal of Immunology.

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2−/−γc−/− Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2006, Journal of Virology.

HIV-1-associated dementia: a basic science and clinical perspective.

H. Gendelman, S. Swindells, H. Gelbard, 2002, The AIDS reader.

The COVID-19 Pandemic: Reflections of Science, Person, and Challenge in Academic Research Settings

H. Gendelman, M. Marcondes, I. Sariyer, 2021, Journal of Neuroimmune Pharmacology.

HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice

H. Gendelman, P. Dash, K. Bidasee, 2020, Scientific Reports.

Efficiency of in situ hybridization as a function of probe size and fixation technique.

H. Gendelman, J. Clements, D. Griffin, 1985, Journal of virological methods.

Development of HIV reservoir targeted long acting nanoformulated antiretroviral therapies.

H. Gendelman, J. McMillan, Benson J. Edagwa, 2014, Current medicinal chemistry.

Lipids and cognition make good bedfellows for neuroAIDS

H. Gendelman, H. Gelbard, 2013, Neurology.

Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules.

H. Gendelman, M. Meltzer, D. Kalter, 1991, Immunology letters.

Plasma Levels of Soluble CD14 and Tumor Necrosis Factor– a Type II Receptor Correlate with Cognitive Dysfunction during Human Immunodeﬁciency Virus Type 1 Infection

H. Gendelman, S. Swindells, Jialin C. Zheng, 2001 .

SARS-CoV-2 Infection Leads to Neurological Dysfunction

H. Gendelman, S. Byrareddy, B. Kevadiya, 2020, Journal of Neuroimmune Pharmacology.

Monocyte biomarkers define sargramostim treatment outcomes for Parkinson's disease

H. Gendelman, Prof Vikas Kumar, R. Mosley, 2022, Clinical and translational medicine.

Animal models for studies of HIV‐1 brain reservoirs

H. Gendelman, P. Dash, S. Gorantla, 2022, Journal of leukocyte biology.

Granulocyte-Macrophage Colony Stimulating Factor Exerts Protective and Immunomodulatory Effects in Cortical Trauma

H. Gendelman, R. Mosley, N. Haverland, 2015, Journal of Neuroimmunology.

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution

H. Gendelman, J. McMillan, B. Sajja, 2018, Theranostics.

AIDS‐associated progressive multifocal leukoencephalopathy (PML)

H. Gendelman, J. Orenstein, G. Pezeshkpour, 1990, Neurology.

Measles encephalomyelitis: Lack of evidence of viral invasion of the central nervous system and quantitative study of the nature of demyelination

N. J. Pressman, H. Gendelman, J. Wolinsky, 1984, Annals of neurology.

CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease

Kosloski, J. Meza, H. Gendelman, 2012, Journal of Neuroimmune Pharmacology.

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2-/- Î3c-/- Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2019 .

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB / cRag 2 / c / Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2017 .

Human Immunodeﬁciency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2 Mice (cid:1)

H. Gendelman, S. Dewhurst, J. Sharp, 2007 .

A double labeling technique for performing immunocytochemistry and in situ hybridization in virus infected cell cultures and tissues.

H. Gendelman, J. Clements, D. Griffin, 1985, Journal of virological methods.

Selection of a fixative for identifying T cell subsets, B cells, and macrophages in paraffin-embedded mouse spleen.

H. Gendelman, D. Griffin, O. Narayan, 1983, Journal of immunological methods.

Animal Model Human Immunodeficiency Virus Encephalitis in SCID Mice

Ellen, H. Gendelman, L. Epstein, 2007 .

Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia

D. Skifter, D. Monaghan, H. Xiong, 2003, Neuroscience Letters.

H. Gendelman, H. Federoff, S. Dewhurst, 2019 .

Infections of the nervous system

H. Gendelman, Y. Persidsky, 2004, The Lancet Neurology.

Mononuclear phagocyte biophysiology influences brain transendothelial and tissue migration: implication for HIV-1-associated dementia

H. Gendelman, M. Zelivyanskaya, I. Chung, 2002, Journal of Neuroimmunology.

Neuroprotective strategies for HIV-1 associated dementia

H. Gendelman, H. Gelbard, R. Mosley, 2009, Neurotoxicity Research.

CD 4 + Regulatory and Effector / Memory T Cell Subsets Profile Motor Dysfunction in Parkinson ’ s Disease

Hesham, J. Meza, H. Gendelman, 2018 .

Role of the β-Chemokine Receptors CCR3 and CCR5 in Human Immunodeficiency Virus Type 1 Infection of Monocytes and Microglia

B. Hyman, C. Mackay, H. Gendelman, 1998, Journal of Virology.

An overview of the clinical and biological features of the AIDS dementia complex.

S. Lipton, I. Grant, H. Gendelman, 2005 .

The neuropathology of HIV-associated brain disease.

S. Lipton, I. Grant, H. Budka, 2005 .

Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis

H. Gendelman, D. Munn, Y. Persidsky, 2002, The Journal of Immunology.

Responses in a Murine Model of HIV-1 Neuroprotective Anti-inflammatory Glial and Copolymer-1 Induces Adaptive Immune

Lynette M. Smith, H. Gendelman, T. Ikezu, 2014 .

Encephalitis Responses in a Murine Model of HIV-1 NeuroprotectiveAnti-inflammatory Glial and Copolymer-1 Induces Adaptive Immune

Lynette M. Smith, H. Gendelman, D. Volsky, 2007 .

A model of human immunodeficiency virus encephalitis in scid mice.

H. Gendelman, C. Power, R. Markham, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease.

H. Gendelman, R. Mosley, Rebecca Banerjee, 2007, Journal of leukocyte biology.

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques

H. Gendelman, J. McMillan, H. Fox, 2019, AIDS.

Induction of IFN-alpha in peripheral blood mononuclear cells by HIV-infected monocytes. Restricted antiviral activity of the HIV-induced IFN.

H. Gendelman, R. Friedman, M. Meltzer, 1992, Journal of immunology.

Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes.

H. Gendelman, C. Dieffenbach, M. Meltzer, 1991, Journal of immunology.

Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-tropic HIV in monocytes and T cells.

D. Burke, H. Gendelman, M. Meltzer, 1990, Journal of immunology.

Dual-Peak Lorentzian CEST MRI for antiretroviral drug brain distribution

H. Gendelman, Aditya N Bade, Yutong Liu, 2022, NeuroImmune pharmacology and therapeutics.

Cell-Mediated Drugs Delivery

H. Gendelman, A. Kabanov, E. Batrakova, 2011 .

Influence of age, irradiation and humanization on NSG mouse phenotypes

A. Epstein, S. Bonasera, H. Gendelman, 2015, Biology Open.

Persistent expression of Ia antigen and viral genome in visna-maedi virus-induced inflammatory cells. Possible role of lentivirus-induced interferon

H. Gendelman, J. Clements, O. Narayan, 1985, The Journal of experimental medicine.

The human immunodeficiency virus long terminal repeat is preferentially expressed in Langerhans cells in transgenic mice.

H. Gendelman, J. Leonard, M. Martin, 1989, AIDS research and human retroviruses.

Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.

H. Gendelman, G. Schifitto, S. Dewhurst, 2007, Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.

C1q–calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease

H. Gendelman, Jialin C. Zheng, Xiaoguang Luo, 2003, Journal of Neuroimmunology.

CCR5 Chemokine Receptor

H. Gendelman, T. Lewis, 2008 .

Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis

H. Gendelman, M. Simm, D. Volsky, 1993, Journal of virology.

Virus-cell membrane fusion does not predict efficient infection of alveolar macrophages by human immunodeficiency virus type 1 (HIV-1).

H. Gendelman, D. Volsky, M. Potash, 1992, Virology.

Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients.

J. Meza, H. Sayles, H. Gendelman, 2013, Nanomedicine.

Debate: “Is Increasing Neuroinflammation Beneficial for Neural Repair?”

V. Perry, H. Gendelman, P. Popovich, 2006, Journal of Neuroimmune Pharmacology.

Innate and Adaptive Immunity in Health and Disease

E. Masliah, H. Gendelman, 2008 .

2and Adaptive Immunity in Health and Disease

E. Masliah, H. Gendelman, 2008 .

Slow, persistent replication of lentiviruses: role of tissue macrophages and macrophage precursors in bone marrow.

H. Gendelman, J. Clements, S. Molineaux, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition.

James L. Buescher, H. Gendelman, R. Ransohoff, 2005, The American journal of pathology.

No direct neuronotoxicity by HIV-1 virions or culture fluids from HIV-1-infected T cells or monocytes.

H. Gendelman, J. Orenstein, M. Meltzer, 1992, AIDS research and human retroviruses.

Facilitated Monocyte-Macrophage Uptake and Tissue Distribution of Superparmagnetic Iron-Oxide Nanoparticles

Alexander Kabanov, Zhiya Ma, Howard E. Gendelman, 2009, PloS one.

Isolation and HIV-1 infection of primary human microglia from fetal and adult tissue.

H. Gendelman, A. Ghorpade, K. Borgmann, 2005, Methods in molecular biology.

Neuroprotective activities of regulatory T cells.

H. Gendelman, S. Appel, 2011, Trends in Molecular Medicine.

Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

J. Luebke, H. Gendelman, Yuzhi Wang, 2020, Brain : a journal of neurology.

HIV-1 cellular and tissue replication patterns in infected humanized mice

H. Gendelman, S. Gorantla, L. Poluektova, 2016, Scientific Reports.

Immunization strategies for Parkinson's disease.

H. Gendelman, R. Mosley, David K. Stone, 2012, Parkinsonism & related disorders.

Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.

H. Gendelman, S. Dewhurst, J. Sharp, 2007, Journal of virology.

The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes.

H. Gendelman, H. Gelbard, J. Reinhard, 1996, Journal of neurovirology.

Simultaneous quantification of intracellular lamivudine and abacavir triphosphate metabolites by LC–MS/MS

H. Gendelman, J. McMillan, N. Gautam, 2018, Journal of pharmaceutical and biomedical analysis.

A long-acting 3TC ProTide nanoformulation suppresses HBV replication in humanized mice.

H. Gendelman, C. Gebhart, N. Osna, 2020, Nanomedicine : nanotechnology, biology, and medicine.

Ultra-long-acting (XLA) antivirals for chronic viral hepatitis

H. Gendelman, V. Soriano, C. de Mendoza, 2021, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Centrifugal Elutriation for Studies of Neuroimmunity

H. Gendelman, S. Gorantla, M. Che, 2014 .

Amplification of Replication Competent HIV-1 by Adoptive Transfer of Human Cells From Infected Humanized Mice

H. Gendelman, K. Khalili, P. Dash, 2020, Frontiers in Cellular and Infection Microbiology.

Novel Delivery System Enhances Efficacy of Antiretroviral Therapy in Animal Model for HIV-1 Encephalitis

H. Gendelman, A. Kabanov, E. Batrakova, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The 2022 outbreak and the pathobiology of the monkeypox virus

H. Gendelman, S. Byrareddy, A. Acharya, 2022, Journal of autoimmunity.

A long acting nanoformulated lamivudine ProTide.

H. Gendelman, J. McMillan, N. Gautam, 2019, Biomaterials.

ProTide generated long-acting abacavir nanoformulations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cc04708a

H. Gendelman, J. McMillan, N. Gautam, 2018, Chemical communications.

Broad-spectrum antivirals.

H. Gendelman, Benson J. Edagwa, 2018 .

Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects

H. Gendelman, S. Swindells, A. Ghorpade, 2005, Journal of Neuroimmunology.

Multipolymer microsphere delivery of SARS-CoV-2 antigens

Md Mahmudul Hasan, H. Gendelman, P. Dash, 2022, Acta Biomaterialia.

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

A. Epstein, H. Gendelman, R. High, 2013, Journal of Neuroimmune Pharmacology.

Advances in neuroimaging for HIV-1 associated neurological dysfunction: clues to the diagnosis, pathogenesis and therapeutic monitoring.

Mariano G. Uberti, H. Gendelman, M. Boska, 2004, Current HIV research.

Biomarkers, Laboratory, and Animal Models for the Design and Development of Adjunctive Therapies for HIV-1 Dementia and other Neuroinflammatory Disorders

H. Gendelman, 2007, Journal of Neuroimmune Pharmacology.

Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain

H. Gendelman, J. McMillan, M. Boska, 2015, Journal of Neuroscience Methods.

HIV-1 Integrase Strand Transfer Inhibitors and Neurodevelopment

H. Gendelman, Aditya N. Bade, Emma G. Foster, 2022, Pharmaceuticals.

Design of mannosylated oral amphotericin B nanoformulation: efficacy and safety in visceral leishmaniasis

H. Gendelman, S. Akhtar, A. Satoskar, 2018, Artificial cells, nanomedicine, and biotechnology.

The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections

H. Gendelman, M. Hasan, Ahmed M. Senan, 2020, Journal of Neuroimmune Pharmacology.

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

H. Gendelman, J. McMillan, K. Khalili, 2019, Nature Communications.

Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants

H. Gendelman, P. Westervelt, J. Orenstein, 1992, Journal of virology.

Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes.

H. Gendelman, P. Westervelt, L. Ratner, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

D. Burke, H. Gendelman, A. Fauci, 1988, The Journal of experimental medicine.

HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise

Jialin Zheng, Howard E. Gendelman, H. Gendelman, 2009, Neurotoxicity Research.

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

Jialin Zheng, Howard E Gendelman, Huangui Xiong, 1999, Journal of Neuroimmunology.

Dementia Immunodeficiency Virus Type 1-Associated Apoptosis : Implications for Human Receptor-Mediated Neural Signaling and Lymphotropic Virions Affect Chemokine

H. Gendelman, L. Epstein, Jialin C. Zheng, 1999 .

Neurobiology and Neural Systems

H. Gendelman, T. Ikezu, 2008 .

Nanocarrier vaccines for SARS-CoV-2

H. Gendelman, D. Oupický, M. Hasan, 2021, Advanced Drug Delivery Reviews.

Oxidative stress and the pathogenesis of neurodegenerative disorders.

Howard E Gendelman, R Lee Mosley, H. Gendelman, 2007, International review of neurobiology.

Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis

H. Gendelman, J. McMillan, S. Akhtar, 2016, Nanomedicine.

Cell-Based Drug Delivery for Improving Antiretroviral Therapeutic Outcomes

H. Gendelman, J. McMillan, 2014 .

Humanized Mice as a Platform for the Development of Long-Acting Nanoformulated Antiretroviral Therapy

H. Gendelman, J. McMillan, 2014 .

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy.

H. Gendelman, A. Fauci, J. Orenstein, 1986, Science.

Neuropathogenesis of human immunodeficiency virus infection.

H. Gendelman, J. McMillan, Christopher J. Woldstad, 2018, Handbook of clinical neurology.

Diagnostics for SARS-CoV-2 infections

H. Gendelman, J. McMillan, M. Hasan, 2021, Nature Materials.

The Immunopathobiology of SARS-CoV-2 Infection

H. Gendelman, M. Hasan, Snigdha Singh, 2021, FEMS microbiology reviews.

Neurological Aspects of Human Immunodeficiency Virus Infection

H. Gendelman, S. Gendelman, 1992 .

Tropism of sheep lentiviruses for monocytes: susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages

H. Gendelman, J. Clements, G. Pezeshkpour, 1986, Journal of virology.

Human immunodeficiency virus type 1 in spinal cords of acquired immunodeficiency syndrome patients with myelopathy: expression and replication in macrophages.

H. Gendelman, J. Orenstein, N. Peress, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus

H. Gendelman, A. Fauci, S. Koenig, 1986, The Journal of experimental medicine.

Inhibition of Indoleamine 2 , 3-dioxygenase ( IDO ) enhances elimination of virus-infected macrophages in animal model of HIV-1 encephalitis

H. Gendelman, D. Munn, O. Takikawa, 2005 .

Functional Proteomic Analysis for Regulatory T Cell Surveillance of the HIV-1-Infected Macrophage

H. Gendelman, David K. Stone, Xiuyan Huang, 2010, Journal of proteome research.

Neuromodulatory Activities of CD4+CD25+ Regulatory T Cells in a Murine Model of HIV-1-Associated Neurodegeneration1

H. Gendelman, Jianuo Liu, R. Mosley, 2009, The Journal of Immunology.

Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases.

H. Gendelman, B. Narasimhan, S. Mallapragada, 2015, Nanomedicine : nanotechnology, biology, and medicine.

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes

H. Gendelman, J. McMillan, Benson J. Edagwa, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Development of europium doped core-shell silica cobalt ferrite functionalized nanoparticles for magnetic resonance imaging.

Howard E Gendelman, H. Gendelman, J. McMillan, 2017, Acta biomaterialia.

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections.

H. Gendelman, J. McMillan, A. Kabanov, 2013, Nanomedicine : nanotechnology, biology, and medicine.

Interferon-(cid:2) and Tumor Necrosis Factor-(cid:3) Regulate Amyloid-(cid:4) Plaque Deposition and (cid:4) -Secretase Expression in Swedish Mutant APP Transgenic Mice

James L. Buescher, Shannon M Walsh, H. Gendelman, 2007 .

Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.

James L. Buescher, Shannon M Walsh, H. Gendelman, 2007, The American journal of pathology.

Animal Model Systems of HIV-Diseases

H. Xiong, H. Gendelman, E. Anderson, 2006 .

Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.

H. Gendelman, V. Sasseville, S. Swindells, 1996, Journal of immunology.

Mononuclear Phagocyte Differentiation, Activation, and Viral Infection Regulate Matrix Metalloproteinase Expression: Implications for Human Immunodeficiency Virus Type 1-Associated Dementia

H. Gendelman, A. Ghorpade, Y. Persidsky, 2001, Journal of Virology.

Impaired Spatial Cognition and Synaptic Potentiation in a Murine Model of Human Immunodeficiency Virus Type 1 Encephalitis

H. Xiong, H. Gendelman, Y. Persidsky, 2002, The Journal of Neuroscience.

Regulation of HIV replication in monocytes by interferon.

H. Gendelman, M. Meltzer, J. Turpin, 1994, Progress in molecular and subcellular biology.

Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120

H. Gendelman, M. Meltzer, J. Bernbaum, 1992, Journal of virology.

LossofInfectivity byProgeny VirusfromAlphaInterferon- Treated HumanImmunodeficiency VirusType1-Infected T Cells IsAssociated withDefective Assembly ofEnvelope gpl20

H. Gendelman, M. Meltzer, J. Bernbaum, 1992 .

Mononuclear phagocytes in the pathogenesis of neurodegenerative diseases

H. Gendelman, Irena Kadiu, J. Kipnis, 2005, Neurotoxicity Research.

Nitrated Alpha-Synuclein and Microglial Neuroregulatory Activities

H. Gendelman, Irena Kadiu, R. Banerjee, 2008, Journal of Neuroimmune Pharmacology.

Proteomic analyses associate cystatin B with restricted HIV-1 replication in placental macrophages.

H. Gendelman, P. Ciborowski, H E Gendelman, 2008, Placenta.

Humanized Mice for Infectious and Neurodegenerative disorders

H. Gendelman, M. Hasan, P. Dash, 2021, Retrovirology.

Macrophages and the human immunodeficiency virus.

H. Gendelman, M. Meltzer, D. Hoover, 1990, Immunology today.

Prodrug Therapies for Infectious and Neurodegenerative Diseases

H. Gendelman, R. Mosley, S. Deodhar, 2022, Pharmaceutics.

Pathways towards human immunodeficiency virus elimination

H. Gendelman, P. Dash, B. Kevadiya, 2020, EBioMedicine.

A Year-Long Extended Release Nanoformulated Cabotegravir Prodrug

J. Meza, H. Gendelman, J. McMillan, 2020, Nature Materials.

Creation of a long-acting rilpivirine prodrug nanoformulation.

H. Gendelman, J. McMillan, H. Fox, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI

A. Epstein, H. Gendelman, M. Boska, 2013, Journal of Neuroimmune Pharmacology.

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

H. Gendelman, J. McMillan, N. Gautam, 2019, International journal of nanomedicine.

Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

Beata J. Wysocki, Howard E. Gendelman, Gang Zhang, 2014, Journal of Virology.

Synthesis of a long acting nanoformulated emtricitabine ProTide.

H. Gendelman, J. McMillan, N. Gautam, 2019, Biomaterials.

Europium sulfide nanoprobes predict antiretroviral drug delivery into HIV-1 cell and tissue reservoirs

H. Gendelman, J. McMillan, M. Hasan, 2021, Nanotheranostics.

Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir

H. Gendelman, J. McMillan, N. Gautam, 2021, Nature Communications.

Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders

H. Gendelman, R. Mosley, B. Kevadiya, 2020, Molecular Neurodegeneration.

The inability of human immunodeficiency virus to infect chimpanzee monocytes can be overcome by serial viral passage in vivo

H. Gendelman, M. Meltzer, B. Poiesz, 1991, Journal of virology.

Mononuclear phagocytes as targets, tissue reservoirs, and immunoregulatory cells in human immunodeficiency virus disease.

H. Gendelman, M. Meltzer, Monte S. Meltzer, 1992, Current topics in microbiology and immunology.

Activation of the human immunodeficiency virus by herpes simplex virus type 1

H. Gendelman, J. Leonard, A. Rabson, 1987, Journal of virology.

An ultralong-acting tenofovir ProTide nanoformulation achieves monthslong HBV suppression

H. Gendelman, N. Osna, M. Ganesan, 2022, Science advances.

Preclinical Pharmacokinetics and Tissue Distribution of Long-Acting Nanoformulated Antiretroviral Therapy

H. Gendelman, J. McMillan, H. Fox, 2013, Antimicrobial Agents and Chemotherapy.

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

H. Gendelman, J. McMillan, H. Fox, 2017, Biomaterials.

Creation of a long-acting nanoformulated dolutegravir

H. Gendelman, J. McMillan, P. Dash, 2018, Nature Communications.

Neuropharmacologic Approaches to Restore the Brain’s Microenvironment

H. Gendelman, Weizhe Li, Yuanan Lu, 2016, Journal of Neuroimmune Pharmacology.

Chapter 5 – The Neuropathogenesis of HIV-1 Infection

H. Gendelman, S. Swindells, H. Gelbard, 2003 .

Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.

H. Gendelman, M. Meltzer, M. Nakamura, 1990, AIDS research and human retroviruses.

Productive, persistent infection of human colorectal cell lines with human immunodeficiency virus

H. Gendelman, A. Fauci, M. Martin, 1987, Journal of virology.

Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice.

H. Gendelman, J. McMillan, P. Dash, 2015, Antiviral research.

Macrophage‐HIV interaction: viral isolation and target cell tropism

H. Gendelman, D. Kalter, Donald S Skillman, 1990, AIDS.

Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs

H. Gendelman, J. McMillan, H. Gelbard, 2017, The Journal of clinical investigation.

Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice

H. Gendelman, Mamoru Ito, S. Gorantla, 2019, Molecular Neurodegeneration.

Immunotherapy for Parkinson’s disease

H. Gendelman, R. Mosley, Mackenzie J. Thurston, 2020, Neurobiology of Disease.

Metabolic drift in the aging brain

G. Siuzdak, A. Epstein, H. Gendelman, 2016, Aging.

Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry.

A. Epstein, H. Gendelman, M. Boska, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Neuroprotective Immunity for Neurodegenerative and Neuroinfectious Diseases

H. Gendelman, R. Mosley, K. E. Olson, 2020 .

The cellular immunology of multiple sclerosis

H. Gendelman, R. Bashir, Howard E. Gendelman, 1999, Journal of leukocyte biology.

Pulsed Stable Isotope Labeling of Amino Acids in Cell Culture Uncovers the Dynamic Interactions between HIV-1 and the Monocyte-Derived Macrophage

Stephanie D. Kraft-Terry, H. Gendelman, H. Fox, 2011, Journal of proteome research.

Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

Howard E. Gendelman, Sankar Ghosh, Jeffrey H. Kordower, 2007, Proceedings of the National Academy of Sciences.

Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases

H. Gendelman, A. Kabanov, E. Batrakova, 2013, PloS one.

HIV-1 gp120 Compromises Blood–Brain Barrier Integrity and Enhance Monocyte Migration across Blood–Brain Barrier: Implication for Viral Neuropathogenesis

Howard E Gendelman, H. Gendelman, Y. Persidsky, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Human Immunodeficiency Virus type 1 Endocytic Trafficking Through Macrophage Bridging Conduits Facilitates Spread of Infection

H. Gendelman, Irena Kadiu, 2011, Journal of Neuroimmune Pharmacology.

Macrophage Bridging Conduit Trafficking of HIV-1 Through the Endoplasmic Reticulum and Golgi Network

H. Gendelman, Irena Kadiu, 2011, Journal of proteome research.

Current Laboratory Methods in Neuroscience Research

Howard E. Gendelman, Huangui Xiong, H. Xiong, 2014, Springer Protocols Handbooks.

CSF proteomic fingerprints for HIV-associated cognitive impairment

Howard E. Gendelman, Wojciech Rozek, Pawel Ciborowski, 2007, Journal of Neuroimmunology.

Investigating the human immunodeficiency virus type 1-infected monocyte-derived macrophage secretome.

Lynette M. Smith, H. Gendelman, Irena Kadiu, 2007, Virology.

CD 4+ T cells in the pathobiology of neurodegenerative disorders

H. Gendelman, R. Mosley, Ashley D. Reynolds, 2009, Journal of Neuroimmunology.

Macrophages, Microglia and Dendritic Cell Function

H. Gendelman, James R. Hilaire, 2017 .

HIV and the Macrophage: From Cell Reservoirs to Drug Delivery to Viral Eradication

H. Gendelman, Jonathan Herskovitz, 2019, Journal of Neuroimmune Pharmacology.

HIV Replication and Persistence in Human Gastrointestinal Cells Cultured In Vitro

H. Gendelman, M. Moyer, 1991, Journal of leukocyte biology.

Infection of human gastrointestinal cells by HIV-1.

H. Gendelman, M. Meltzer, M. Moyer, 1990, AIDS research and human retroviruses.

HUMAN IMMUNODEFICIENCY VIRUS ON RECOMBINANT COLONY-STIMULATING FACTOR I-TREATED MONOCYTES

D. Burke, H. Gendelman, J. Orenstein, 1988 .

Alpha interferon-induced antiretroviral activities: restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes

H. Gendelman, M. Stevenson, L. Baca-Regen, 1994, Journal of virology.

Mononuclear phagocyte immunity and the neuropathogenesis of HIV‐1 infection

H. Gendelman, Y. Persidsky, 2003, Journal of leukocyte biology.

HIV‐1‐Associated Dementia: A Metabolic Encephalopathy Perpetrated by Virus‐Infected and Immune‐Competent Mononuclear Phagocytes

H. Xiong, H. Gendelman, W. Zink, 2002, Journal of acquired immune deficiency syndromes.

Molecular characterization of a polymerase mutant human immunodeficiency virus.

H. Gendelman, M. Martin, S. Venkatesan, 1987, Virology.

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

M. Emerman, M. Bukrinsky, H. Gendelman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Quantitative 1H Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy in an Animal Model of Parkinson's Disease

H. Gendelman, C. Destache, E. Benner, 2005, The Journal of Neuroscience.

Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease

K. Hasan, H. Gendelman, Irena Kadiu, 2006, Clinical Neuroscience Research.

Pathways Toward a Functional HIV-1 Cure: Balancing Promise and Perils of CRISPR Therapy.

H. Gendelman, B. Kevadiya, Mahmudul Hasan, 2022, Methods in molecular biology.

Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA

H. Gendelman, L. Epstein, S. Perry, 1995, Molecular and cellular biology.

Dementia Associated with the Acquired Immunodeficiency Syndrome

Howard E. Gendelman, Stuart A. Lipton, S. Lipton, 1995 .

Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.

H. Gendelman, Honghong Yao, S. Buch, 2010, Blood.

Murine Motor and Behavior Functional Evaluations for Acute 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Intoxication

H. Gendelman, R. Mosley, Jessica A. L. Hutter-Saunders, 2012, Journal of Neuroimmune Pharmacology.

Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte‐associated inflammation and neurotoxicity

H. Gendelman, W. Burke, Jialin C. Zheng, 1999, Journal of leukocyte biology.

Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms

H. Gendelman, L. Epstein, 1993, Annals of neurology.

IN SITU HYBRIDIZATION FOR DETECTION OF VIRAL NUCLEIC ACID IN CELL CULTURES AND TISSUES

H. Gendelman, W. Tourtellotte, P. Shapshak, 1986 .

Monocyte Chemotactic Protein-1 Regulates Voltage-Gated K+ Channels and Macrophage Transmigration

H. Xiong, H. Gendelman, Jianuo Liu, 2009, Journal of Neuroimmune Pharmacology.

STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier.

H. Gendelman, Bo Yang, Y. Persidsky, 2008, Blood.

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy

H. Gendelman, R. Mosley, S. Gorantla, 2017, Retrovirology.

Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: A therapeutic strategy based on modulation of mixed lineage kinase

H. Gendelman, S. Dewhurst, H. Gelbard, 2010, Neurotherapeutics.

Fusobacterium necrophorum causing infective endocarditis and liver and splenic abscesses.

H. Gendelman, B. Miriovsky, U. Sandkovsky, 2011, Revista do Instituto de Medicina Tropical de Sao Paulo.

A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson’s Disease

Jenell R. Smith, Scott J. Shandler, H. Gendelman, 2019, Front. Cell. Neurosci..

Molecular pathogenesis of human immunodeficiency virus infection.

H. Gendelman, S. Koenig, A. Rabson, 1988, Gene analysis techniques.

Immunopathogenesis of human immunodeficiency virus infection in the central nervous system

H. Gendelman, J. Leonard, M. Meltzer, 1988, Annals of neurology.

Commentary: Animal Models of NeuroAIDS

H. Gendelman, H. Fox, 2012, Journal of Neuroimmune Pharmacology.

Rodent models for HIV-associated neurocognitive disorders

H. Gendelman, S. Gorantla, L. Poluektova, 2012, Trends in Neurosciences.

Immunopathology and Infectious Diseases Links between Progressive HIV-1 Infection of Humanized Mice and Viral Neuropathogenesis

H. Gendelman, C. Gebhart, S. Gorantla, 2010 .

Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms.

H. Gendelman, Y. Persidsky, 2002, Journal of neurovirology.

The neuropathogenesis of HIV‐1 infection

S. Lipton, M. Bukrinsky, H. Gendelman, 1994, Handbook of clinical neurology.

Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome.

S. Lipton, H. Gendelman, 1995, The New England journal of medicine.

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

H. Gendelman, E. Benner, S. Przedborski, 2008, PloS one.

Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.

H. Gendelman, M. Boska, A. Kabanov, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Development of a rapid autopsy program for studies of brain immunity

H. Gendelman, S. Swindells, A. Ghorpade, 2005, Journal of Neuroimmunology.

Monocytes, dendritic cells, and Langerhans cells in human immunodeficiency virus infection.

H. Gendelman, M. Meltzer, D. Kalter, 1991, Dermatologic clinics.

Introducing Neuroimmune Pharmacology

H. Gendelman, T. Ikezu, 2008 .

Overexpression of monocyte chemotactic protein-1/ CCL2 in β-amyloid precursor protein transgenic mice show accelerated diffuse β-amyloid deposition

James L. Buescher, H. Gendelman, R. Ransohoff, 2005 .

Overview of Mononuclear Phagocytes

H. Gendelman, Mary G. Banoub, 2017 .

Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation

H. Gendelman, Irena Kadiu, Jianuo Liu, 2007, Journal of neurochemistry.

Simvastatin Inhibits the Activation of p21ras and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

H. Gendelman, K. Pahan, J. Matras, 2009, The Journal of Neuroscience.

A Coat of Many Colors: Neuroimmune Crosstalk in Human Immunodeficiency Virus Infection

Stephanie D. Kraft-Terry, H. Gendelman, S. Buch, 2009, Neuron.

Proteomic Modeling for HIV-1 Infected Microglia-Astrocyte Crosstalk

David J. Volsky, Howard E. Gendelman, Stephanie D. Kraft-Terry, 2008, PloS one.

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV- associated neurological disease

S. Lipton, M. Bukrinsky, H. Gendelman, 1995, The Journal of experimental medicine.

Alzheimer’s disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission

J. Luebke, H. Gendelman, Yuzhi Wang, 2020 .

Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice

H. Gendelman, D. Volsky, M. Potash, 2018, Journal of NeuroVirology.

SCID mice with HIV encephalitis develop behavioral abnormalities.

H. Gendelman, Y. Persidsky, W. Tyor, 1998, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Neuroimmune cross talk and HIV-associated neurocognitive disorders

H. Gendelman, J. McMillan, 2013 .

Huntington's Disease

H. Gendelman, T. Ikezu, S. Gendelman, 2008 .

Regulation of Human Immunodeficiency Virus Type 1 Infection, β-Chemokine Production, and CCR5 Expression in CD40L-Stimulated Macrophages: Immune Control of Viral Entry

H. Gendelman, Jialin C. Zheng, Johnny J. He, 2001, Journal of Virology.

Endosomal Trafficking of Nanoformulated Antiretroviral Therapy 2

Harris, H. Gendelman, J. McMillan, 2014 .

Particle Carriage and HIV Clearance Antiretroviral Therapy Facilitates Drug Endosomal Trafficking of Nanoformulated

H. Gendelman, J. McMillan, T. Wysocki, 2014 .

Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection.

H. Gendelman, M. Meltzer, D. Kalter, 1990, Annual review of immunology.

Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders?

H. Gendelman, S. Gorantla, L. Poluektova, 2012, Journal of Neuroimmune Pharmacology.

leukocyte transmigration across the blood-brain barrier STAT1 signaling modulates HIV-1-induced inflammatory responses and

H. Gendelman, Bo Yang, Y. Persidsky, 2013 .

STAT 1 signaling modulates HIV-1 – induced inflammatory responses and leukocyte transmigration across the blood-brain barrier

H. Gendelman, Bo Yang, Y. Persidsky, 2007 .

Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.

H. Gendelman, S. Swindells, A. Ghorpade, 1998, The Journal of infectious diseases.

Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines.

Anup D. Sharma, H. Gendelman, B. Narasimhan, 2015, Nanomedicine : nanotechnology, biology, and medicine.

Nanomedicines for nervous system diseases

H. Gendelman, J. McMillan, Dongwei Guo, 2014 .

NanoART, neuroAIDS and CNS drug delivery.

H. Gendelman, Ari S. Nowacek, 2009, Nanomedicine.

UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues.

H. Gendelman, J. McMillan, N. Gautam, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Ultra-long-acting antivirals as chemical vaccines to prevent viral diseases.

H. Gendelman, V. Soriano, Benson J. Edagwa, 2022, Future microbiology.

Psychosocial aspects of neurological impairment in children with AIDS.

S. Lipton, I. Grant, H. Gendelman, 2005 .

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery.

H. Gendelman, Ari S. Nowacek, J. McMillan, 2009, Nanomedicine.

Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery.

H. Gendelman, C. Destache, M. Boska, 2006, Blood.

Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation

H. Gendelman, J. McMillan, A. Dahan, 2022, Nature Communications.

Creation of a long-acting nanoformulated dolutegravir

H. Gendelman, J. McMillan, P. Dash, 2018, Nature Communications.

Modulating cellular autophagy for controlled antiretroviral drug release.

H. Gendelman, J. McMillan, H. Gelbard, 2018, Nanomedicine.

Biodegradable polyanhydride-based nanomedicines for blood to brain drug delivery.

H. Gendelman, B. Narasimhan, S. Mallapragada, 2018, Journal of biomedical materials research. Part A.

EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment

H. Gendelman, J. McMillan, O. Arancio, 2018, PLoS pathogens.

SARS-CoV-2 Infection Leads to Neurological Dysfunction

H. Gendelman, S. Byrareddy, B. Kevadiya, 2020, Journal of Neuroimmune Pharmacology.

Regulation of HIV1 replication by interferon alpha: from laboratory bench to bedside.

H. Gendelman, S. Swindells, L. Loomis, 1994, Research in immunology.

A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes

H. Gendelman, R. Friedman, C. Dieffenbach, 1991, The Journal of experimental medicine.

Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders

H. Gendelman, R. Mosley, Katherine A. Estes, 2014, Translational Neurodegeneration.

Methamphetamine-Associated Psychosis

R. Bevins, H. Gendelman, Ming Li, 2011, Journal of Neuroimmune Pharmacology.

Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases

H. Gendelman, R. Mosley, David K. Stone, 2010, Journal of neurochemistry.

Control of neuroinflammation as a therapeutic strategy for amyotrophic lateral sclerosis and other neurodegenerative disorders

H. Gendelman, R. Mosley, 2010, Experimental Neurology.

Innate and adaptive immunity for the pathobiology of Parkinson's disease.

H. Gendelman, R. Mosley, David K. Stone, 2009, Antioxidants & redox signaling.

Inhibition of matrix metalloproteinases by HIV-1 integrase strand transfer inhibitors

Nicholas Y. Palermo, H. Gendelman, Yutong Liu, 2023, Frontiers in Toxicology.

Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease.

H. Gendelman, C. Destache, E. Benner, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis

H. Gendelman, Jianuo Liu, R. Mosley, 2011, Journal of Neuroimmunology.

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

H. Xiong, H. Gendelman, R. Ransohoff, 2009, PloS one.

URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease

H. Gendelman, T. Kiyota, Gang Zhang, 2018, Journal of Neuroinflammation.

AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice.

H. Gendelman, R. Ransohoff, W. Klein, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Elucidating the pathogenic mechanisms of AD brain‐derived, tau‐containing extracellular vesicles: Highly transmissible and preferential propagation to GABAergic neurons

H. Gendelman, R. Kayed, T. Ikezu, 2020, Alzheimer's & Dementia.

Inflammation and adaptive immunity in Parkinson's disease.

H. Gendelman, R. Mosley, Jessica A. L. Hutter-Saunders, 2012, Cold Spring Harbor perspectives in medicine.

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice

H. Gendelman, J. McMillan, Donald W. Harms, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Neural Immunity and Human Immunodeficiency Virus-1-Associated Dementia

H. Xiong, H. Gendelman, S. Swindells, 2004 .

HIV-1-Infected Astrocytes and the Microglial Proteome

David J. Volsky, Howard E. Gendelman, Stephanie D. Kraft-Terry, 2008, Journal of Neuroimmune Pharmacology.

Regulation of HIV replication in infected monocytes by IFN-alpha. Mechanisms for viral restriction.

H. Gendelman, J. Orenstein, R. Friedman, 1990, Journal of immunology.

Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment

H. Gendelman, J. McMillan, Yutong Liu, 2021, Molecular Neurobiology.

Cytokine-Stimulated, But Not HIV-Infected, Human Monocyte-Derived Macrophages Produce Neurotoxic Levels of l-Cysteine1

M. Kaul, S. Lipton, H. Gendelman, 2000, The Journal of Immunology.

Produce Neurotoxic Levels of l-Cysteine Human Monocyte-Derived Macrophages Cytokine-Stimulated, But Not HIV-Infected,

M. Kaul, H. Gendelman, Jialin C. Zheng, 2000 .

Immunotherapies for Movement Disorders: Parkinson’s Disease and Amyotrophic Lateral Sclerosis

H. Gendelman, R. Mosley, C. Schutt, 2017 .

Chemokines and the Neuropathogenesis of HIV-1 Infection

H. Gendelman, Jialin C. Zheng, Dawn Eggert, 2009 .

Chemokines and Their Receptors and the Neuropathogenesis of HIV-1 Infection

H. Gendelman, Jialin C. Zheng, L. Meléndez, 2006 .

Nanotechnology: A Focus on Nanoparticles as a Drug Delivery System

Christopher J. Destache, Howard E. Gendelman, Huanyu Dou, 2006, Journal of Neuroimmune Pharmacology.

Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson’s disease trial

G. Siuzdak, T. Wilson, J. Meza, 2017, npj Parkinson's Disease.

CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease

J. Meza, H. Gendelman, D. Standaert, 2012, Journal of Neuroimmune Pharmacology.

Defining the Innate Immune Responses for SARS-CoV-2-Human Macrophage Interactions

H. Gendelman, Prof Vikas Kumar, R. Mosley, 2021, Frontiers in Immunology.

Comparative manufacture and cell-based delivery of antiretroviral nanoformulations

H. Gendelman, Ari S. Nowacek, J. McMillan, 2011, International journal of nanomedicine.

Development of a porous layer-by-layer microsphere with branched aliphatic hydrocarbon porogens.

Md Mahmudul Hasan, H. Gendelman, I. Andreu, 2022, Nanomedicine : nanotechnology, biology, and medicine.

CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination

H. Gendelman, J. McMillan, R. Mosley, 2021, EBioMedicine.

Recovery of Latent HIV-1 from Brain Tissue by Adoptive Cell Transfer in Virally Suppressed Humanized Mice

H. Gendelman, P. Dash, S. Gorantla, 2021, Journal of Neuroimmune Pharmacology.

Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains

H. Gendelman, Weizhe Li, S. Gorantla, 2017, Disease Models & Mechanisms.

Neuropathologic and neuroinflammatory activities of HIV‐1‐infected human astrocytes in murine brain

Lynette M. Smith, H. Gendelman, D. Volsky, 2006, Glia.

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

H. Gendelman, J. McMillan, K. Khalili, 2019, Nature Communications.

Development of laboratory and animal model systems for HIV‐1 encephalitis and its associated dementia

H. Gendelman, Y. Persidsky, 1997, Journal of leukocyte biology.

Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice

H. Gendelman, P. Dash, S. Gorantla, 2019, Front. Immunol..

Long-acting slow effective release antiretroviral therapy

H. Gendelman, J. McMillan, Benson J. Edagwa, 2017, Expert opinion on drug delivery.

CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

H. Gendelman, S. Dewhurst, C. Gebhart, 2010, The Journal of Immunology.

Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

H. Gendelman, J. McMillan, P. Ciborowski, 2015, Retrovirology.

HIV neurocognitive disorders.

S. Lipton, I. Grant, H. Gendelman, 2005 .

Memantine Protects Hippocampal Neuronal Function in Murine Human Immunodeficiency Virus Type 1 Encephalitis

H. Xiong, H. Gendelman, E. Anderson, 2004, The Journal of Neuroscience.

The Neurology of AIDS

Susan Swindells, Stuart A. Lipton, Ian P. Everall, 1998 .

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice

Howard E. Gendelman, Michael D. Boska, Prasanta K. Dash, 2015, Molecular Neurobiology.

Neurobiology of Disease Quantitative 1 H Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy in an Animal Model of Parkinson ’ s Disease

Mariano G. Uberti, H. Gendelman, C. Destache, 2005 .

Macrophages, Microglia, and Dendritic C

H. Gendelman, J. Kipnis, A. Ghorpade, 2008 .

Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson’s disease

H. Gendelman, R. Mosley, C. Schutt, 2018, Molecular Neurodegeneration.

Neuroprotective Mechanisms of Lithium in Murine Human Immunodeficiency Virus-1 Encephalitis

H. Xiong, H. Gendelman, S. Dewhurst, 2005, The Journal of Neuroscience.

Presenilin-1 familial Alzheimer’s disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice

H. Xiong, H. Gendelman, T. Kiyota, 2015, Brain, Behavior, and Immunity.

CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease

H. Gendelman, T. Kiyota, Mohit M. Jain, 2013, Neurobiology of Aging.

Blood-borne macrophage-neural cell interactions hitchhike on endosome networks for cell-based nanozyme brain delivery.

H. Gendelman, Irena Kadiu, M. Sokolsky-Papkov, 2012, Nanomedicine.

Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson's disease.

H. Gendelman, M. Boska, A. Kabanov, 2010, Nanomedicine.

Epidermal Langerhans cells are not principal reservoirs of virus in HIV disease.

H. Gendelman, J. Orenstein, M. Meltzer, 1991, Journal of immunology.

Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS

H. Gendelman, J. Rothstein, J. Julien, 2007, Neurobiology of Disease.

AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease

Weiguo Dong, Howard E Gendelman, Gang Zhang, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Exosomes and Neuroregulation

H. Gendelman, Denise A. Cobb, 2017 .

Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

H. Gendelman, S. Markey, M. Heyes, 2001, Journal of Neuroimmunology.

Neuroprotective Activities of Sodium Valproate in a Murine Model of Human Immunodeficiency Virus-1 Encephalitis

H. Gendelman, S. Dewhurst, H. Gelbard, 2003, The Journal of Neuroscience.

A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis*

H. Gendelman, R. Banerjee, A. Ghorpade, 2006, Journal of Biological Chemistry.

Effects of colony stimulating factors on the interaction of monocytes and the human immunodeficiency virus.

H. Gendelman, M. Meltzer, Monte S. Meltzer, 1988, Immunology letters.

Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacity.

Han Liu, H. Xiong, H. Gendelman, 2013, Journal of proteome research.

Pathways towards an effective immunotherapy for Parkinson’s disease

H. Gendelman, R. Mosley, Jessica A. L. Hutter-Saunders, 2011, Expert review of neurotherapeutics.

Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease

H. Gendelman, K. Pahan, Xiaojuan Liu, 2012, PloS one.

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations.

D. Dimitrov, H. Gendelman, J. McMillan, 2015, Biomaterials.

Immunoregulation of a CB2 Receptor Agonist in a Murine Model of NeuroAIDS

H. Gendelman, S. Gorantla, E. Makarov, 2010, Journal of Neuroimmune Pharmacology.

Plasma proteomic analysis of simian immunodeficiency virus infection of rhesus macaques.

James R. Anderson, H. Gendelman, H. Fox, 2010, Journal of proteome research.

Registration of in vivo MR to histology of rodent brains using blockface imaging

Mariano G. Uberti, Michael D. Boska, Huanyu Dou, 2009, Medical Imaging.

Ingress of blood-borne macrophages across the blood-brain barrier in murine HIV-1 encephalitis

Mariano G. Uberti, Howard E. Gendelman, Michael D. Boska, 2008, Journal of Neuroimmunology.

Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery

H. Gendelman, C. Destache, M. Boska, 2006, Journal of leukocyte biology.

Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS1

H. Gendelman, J. McMillan, C. Destache, 2009, The Journal of Immunology.

Model of NeuroAIDS Antiretroviral Drug to the Brain in a Murine Macrophage Delivery of Nanoformulated

H. Gendelman, J. McMillan, C. Destache, 2009 .

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

H. Gendelman, T. Kiyota, P. Ciborowski, 2016, Journal of Neuroimmune Pharmacology.

The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy.

H. Gendelman, J. McMillan, T. Wysocki, 2016, Nanomedicine : nanotechnology, biology, and medicine.

vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus

H. Gendelman, P. Sova, D. Volsky, 1996, Journal of virology.

Proteomic analyses of monocytes obtained from Hispanic women with HIV‐associated dementia show depressed antioxidants

Stephanie D. Kraft-Terry, H. Gendelman, V. Wojna, 2010, Proteomics. Clinical applications.

AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice.

H. Gendelman, R. Ransohoff, W. Klein, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: a preliminary report

H. Gendelman, C. Destache, P. Ciborowski, 2004, Journal of Neuroimmunology.

Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment.

Howard E Gendelman, Wojciech Rozek, Pawel Ciborowski, 2007, Journal of proteome research.

Parkinson's Disease and Amyotrophic Lateral Sclerosis

H. Gendelman, R. Mosley, David K. Stone, 2008 .

HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: Relevance for HIV-1-associated dementia

Jialin Zheng, Huangui Xiong, H. Xiong, 2001, Neurotoxicity Research.

Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function

Jenae Limoges, Howard E Gendelman, Huangui Xiong, 2003, Journal of Neuroimmunology.

The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation

H. Gendelman, T. Kiyota, H. Gelbard, 2016, Journal of Neuroinflammation.

Motor Function in Rodent Models of Neurodegenerative Disorders

H. Gendelman, R. Mosley, J. Saunders, 2014 .

Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages

H. Gendelman, H. Gelbard, S. Gorantla, 2019, Journal of Neuroimmune Pharmacology.

HIV-1 neuroimmunity in the era of antiretroviral therapy

Stephanie D. Kraft-Terry, H. Gendelman, S. Buch, 2010, Neurobiology of Disease.

Mononuclear phagocytes mediate blood‐brain barrier compromise and neuronal injury during HIV‐1‐associated dementia

H. Gendelman, Jialin C. Zheng, Y. Persidsky, 2000, Journal of leukocyte biology.

Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages

Wei Zhang, H. Gendelman, Irena Kadiu, 2012, The Journal of Immunology.

Neurodegenerative disorders and nanoformulated drug development.

H. Gendelman, Ari S. Nowacek, L. M. Kosloski, 2009, Nanomedicine.

Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients

H. Gendelman, H. Mitsumoto, P. Gordon, 2007, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

The neuropathogenesis of HIV-1 infection.

S. Lipton, M. Bukrinsky, H. Gendelman, 1999, Journal of leukocyte biology.

Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders

H. Gendelman, H. Gelbard, 2014, Current opinion in HIV and AIDS.

HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: New insights into blood–brain barrier dysfunction for HIV-1-associated dementia

Howard E. Gendelman, Wojciech Rozek, Pawel Ciborowski, 2007, Journal of Neuroimmunology.

The spectrum of peripheral neuropathies in AIDS.

S. Lipton, I. Grant, H. Gendelman, 2005 .

The neuropathology of HIV-related neuropathies.

S. Lipton, I. Grant, H. Gendelman, 2005 .

Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia

H. Gendelman, Jialin C. Zheng, S. Morgello, 2003, Journal of Neuroimmunology.

Multidimensional protein fractionation using ProteomeLab PF 2D™ for profiling amyotrophic lateral sclerosis immunity: A preliminary report

H. Gendelman, P. Ciborowski, R. Mosley, 2008, Proteome Science.

CNS expression of anti‐inflammatory cytokine interleukin‐4 attenuates Alzheimer's disease‐like pathogenesis in APP+PS1 bigenic mice

H. Gendelman, T. Kiyota, T. Ikezu, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Brain region mapping using global metabolomics.

G. Siuzdak, A. Epstein, H. Gendelman, 2014, Chemistry & biology.

Control of Neuroinflammation for Therapeutic Gain

H. Gendelman, E. Benner, 2017 .

HIV-1 vaccines.

S. Lipton, I. Grant, H. Gendelman, 2005 .

Monocyte Differentiation, Activation, and Mycobacterial Killing Are Linked to Transsulfuration-dependent Redox Metabolism*

H. Gendelman, R. Banerjee, S. Garg, 2006, Journal of Biological Chemistry.

Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids

G. Siuzdak, A. Epstein, H. Gendelman, 2015, Nature Communications.

Neuroimmune Pharmacology 2nd Edition

H. Gendelman, M. Cosentino, M. Eliezer, 2017 .

Cytokine and viral gene expression during infection of monocytes by the human immunodeficiency virus: central role of interferons in the promotion and resolution of virus infection

H. Gendelman, M. Meltzer, 1992 .

Booster immunization of HIV-1 negative volunteers with HGP-30 vaccine induces protection against HIV-1 virus challenge in SCID mice.

J. Kahn, H. Gendelman, J. Talmadge, 1999, Vaccine.

Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment

Derick R. Peterson, H. Gendelman, G. Schifitto, 2009, Journal of NeuroVirology.

Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice.

J. Meza, H. Gendelman, J. McMillan, 2012, The Journal of infectious diseases.

Europium-Doped Cerium Oxide Nanoparticles for Microglial Amyloid Beta Clearance and Homeostasis.

H. Xiong, H. Gendelman, R. Mosley, 2022, ACS chemical neuroscience.

Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking.

A. Mohs, H. Gendelman, J. McMillan, 2019, Biomaterials.

Surface-engineered multimodal magnetic nanoparticles to manage CNS diseases.

H. Gendelman, M. Nair, K. Khalili, 2019, Drug discovery today.

Development and characterization of a long-acting nanoformulated abacavir prodrug.

H. Gendelman, J. McMillan, Dhirender Singh, 2016, Nanomedicine.

Pharmacokinetics, Biodistribution, and Toxicity of Folic Acid-Coated Antiretroviral Nanoformulations

H. Gendelman, J. McMillan, H. Fox, 2014, Antimicrobial Agents and Chemotherapy.

Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy

H. Gendelman, J. McMillan, R. Mosley, 2015, PloS one.

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

H. Gendelman, J. McMillan, H. Gelbard, 2012, AIDS.

The Promise and Perils of CNS Drug Delivery: A Video Debate

H. Gendelman, A. Kabanov, J. Linder, 2008, Journal of Neuroimmune Pharmacology.

Synthesis and Characterization of Long Acting Darunavir Prodrugs.

H. Gendelman, J. McMillan, N. Gautam, 2019, Molecular pharmaceutics.

Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques

H. Gendelman, J. McMillan, H. Fox, 2017, Antimicrobial Agents and Chemotherapy.

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.

H. Gendelman, Ari S. Nowacek, J. McMillan, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders

H. Gendelman, R. Mosley, B. Kevadiya, 2020, Molecular Neurodegeneration.

Restriction of HIV replication in infected T cells and monocytes by interferon-alpha.

H. Gendelman, J. Orenstein, R. Friedman, 1990, AIDS research and human retroviruses.

Nitrated alpha‐synuclein‐activated microglial profiling for Parkinson’s disease

H. Gendelman, Irena Kadiu, Mark P Thomas, 2008, Journal of neurochemistry.

Formulation design facilitates magnetic nanoparticle delivery to diseased cells and tissues.

H. Gendelman, J. McMillan, M. Sokolsky-Papkov, 2014, Nanomedicine.

CD4+ effector T cells accelerate Alzheimer’s disease in mice

H. Gendelman, T. Kiyota, R. Mosley, 2021, Journal of neuroinflammation.

Cytoskeletal Protein Transformation in HIV-1-Infected Macrophage Giant Cells1

Howard E. Gendelman, Pawel Ciborowski, H. Gendelman, 2007, The Journal of Immunology.

Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages.

H. Gendelman, C. Destache, L. Shlyakhtenko, 2007, Virology.

T cell independent mechanism for copolymer‐1‐induced neuroprotection

H. Gendelman, J. Kipnis, S. Caplan, 2007, European journal of immunology.

Small magnetite antiretroviral therapeutic nanoparticle probes for MRI of drug biodistribution.

H. Gendelman, J. McMillan, B. Sajja, 2014, Nanomedicine.

Erratum to “CSF proteomic fingerprints for HIV-associated cognitive impairment” [J. Neuroimmunol. 192(2007)157–170]

H. Gendelman, V. Wojna, J. Rodríguez-Orengo, 2008, Journal of Neuroimmunology.

Neuroregulatory Events Follow Adaptive Immune-Mediated Elimination of HIV-1-Infected Macrophages: Studies in a Murine Model of Viral Encephalitis1

H. Gendelman, S. Gorantla, H. Dou, 2004, The Journal of Immunology.

Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection.

James R. Anderson, H. Gendelman, S. Swindells, 2001, The Journal of infectious diseases.

Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study

H. Gendelman, V. Wojna, E. Kraiselburd, 2011, Journal of NeuroVirology.

OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis

E. Masliah, H. Gendelman, D. Langford, 2004, Journal of Neuroimmunology.

An interactive cluster heat map to visualize and explore multidimensional metabolomic data

Gary Siuzdak, Howard E. Gendelman, Michael D. Boska, 2015, Metabolomics.

Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice

H. Gendelman, T. Kiyota, R. Mosley, 2018, Journal of Neuroimmunology.

Regulation of tissue inhibitor of metalloproteinase‐1 by astrocytes: Links to HIV‐1 dementia

H. Gendelman, A. Ghorpade, K. Borgmann, 2003, Glia.

A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders

H. Gendelman, R. Mosley, 2015, Journal of Neuroimmune Pharmacology.

Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI

A. Epstein, H. Gendelman, M. Boska, 2013, Journal of Neuroimmune Pharmacology.

Landmark Optimization Using Local Curvature for Point-Based Nonlinear Rodent Brain Image Registration

Yutong Liu, Balasrinivasa Rao Sajja, Mariano G. Uberti, 2011, Int. J. Biomed. Imaging.

Medicinal Chemistry and Brain Drug Penetrance

H. Gendelman, James R. Hilaire, 2017 .

Proteomic analysis of mesenchymal to Schwann cell transdifferentiation.

Anup D. Sharma, H. Gendelman, S. Mallapragada, 2017, Journal of proteomics.

Non-neuronal interactions in HIV-1-associated dementia

H. Gendelman, A. Ghorpade, 2003 .

Macrophages, chemokines and neuronal injury in HIV-1-associated dementia.

Jialin Zheng, Howard E Gendelman, H. Gendelman, 2002, Cellular and molecular biology.

Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage

H. Gendelman, Ari S. Nowacek, J. McMillan, 2011, Nanotoxicology.

4-Aminopyridine Improves Spatial Memory in a Murine Model of HIV-1 Encephalitis

H. Xiong, H. Gendelman, H. Dou, 2009, Journal of Neuroimmune Pharmacology.

Safety, tolerability, and immune-biomarker profiling for year-long sargramostim treatment of Parkinson's disease

H. Gendelman, R. Mosley, Pamela Santamaria, 2021, EBioMedicine.

Change in Evolution

H. Gendelman, 2012, Journal of Neuroimmune Pharmacology.

Neuroprotective Activities of Long-Acting Granulocyte–Macrophage Colony-Stimulating Factor (mPDM608) in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Intoxicated Mice

H. Gendelman, S. Joseph, R. Mosley, 2020, Neurotherapeutics.

A quantitation of myelin‐associated glycoprotein and myelin basic protein loss in different demyelinating disease

N. J. Pressman, H. Gendelman, J. Wolinsky, 1985, Annals of neurology.

Interview: Nanomedicine and the fight against HIV/AIDS.

H. Gendelman, A. Nel, S. Swindells, 2014, Nanomedicine.

Methods Development for Blood Borne Macrophage Carriage of Nanoformulated Antiretroviral Drugs

H. Gendelman, Ari S. Nowacek, J. McMillan, 2010, Journal of visualized experiments : JoVE.

An experimental model system for HIV-1-induced brain injury.

H. Gendelman, M. Jett, H. Nottet, 1994, Advances in neuroimmunology.

A Role for Extracellular Vesicles in SARS-CoV-2 Therapeutics and Prevention

H. Gendelman, D. Oupický, M. Hasan, 2021, Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.

Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson’s disease

H. Gendelman, R. Mosley, C. Schutt, 2018, Molecular Neurodegeneration.

The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia

H. Gendelman, S. Swindells, Y. Persidsky, 2001, Journal of Neuroimmunology.

CD4+ effector T cells accelerate Alzheimer’s disease in mice

H. Gendelman, T. Kiyota, R. Mosley, 2021, Journal of Neuroinflammation.

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson’s disease

H. Gendelman, R. Banerjee, Mark P Thomas, 2007, Journal of neurochemistry.

Structural brain imaging.

S. Lipton, T. Jernigan, I. Grant, 2005 .

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice

H. Gendelman, B. Sajja, M. Boska, 2016, Molecular Neurobiology.

Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson’s Disease

Scott J. Shandler, H. Gendelman, M. Boska, 2016, Neurotherapeutics.

Generation and Disease Model Relevance of a Manganese Enhanced Magnetic Resonance Imaging-Based NOD/scid-IL-2Rγcnull Mouse Brain Atlas

H. Gendelman, B. Sajja, M. Boska, 2016, Journal of Neuroimmune Pharmacology.

Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice

H. Gendelman, D. Volsky, M. Potash, 2018, Journal of NeuroVirology.

Neuroprotective Activities of CEP-1347 in Models of NeuroAIDS

H. Gendelman, G. Schifitto, S. Dewhurst, 2009, The Journal of Immunology.

Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis1

H. Gendelman, D. Munn, Y. Persidsky, 2002, The Journal of Immunology.

The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation

H. Gendelman, T. Kiyota, H. Gelbard, 2016, Journal of Neuroinflammation.

Jialin Zheng, Howard E. Gendelman, H. Gendelman, 2004, Journal of Neuroimmunology.

Proteomic biosignatures for monocyte-macrophage differentiation.

Stephanie D. Kraft-Terry, H. Gendelman, 2011, Cellular immunology.

Isolation, propagation, and HIV-1 infection of monocyte-derived macrophages and recovery of virus from brain and cerebrospinal fluid.

H. Gendelman, S. Gorantla, M. Che, 2005, Methods in molecular biology.

Human immunodeficiency virus-mononuclear phagocyte interactions: emerging avenues of biomarker discovery, modes of viral persistence and disease pathogenesis.

H. Gendelman, P. Ciborowski, 2006, Current HIV research.

Review: neuronal injury in HIV infection.

H. Gendelman, C. Wiley, C. Petito, 1999, Journal of neurovirology.

Mouse brain fixation to preserve In vivo manganese enhancement for ex vivo manganese‐enhanced MRI

Howard E Gendelman, H. Gendelman, B. Sajja, 2013, Journal of magnetic resonance imaging : JMRI.

Defining the Immune Responses for SARS-CoV-2-Human Macrophage Interactions

H. Gendelman, R. Mosley, S. Byrareddy, 2021, bioRxiv.

The new non-nucleoside reverse transcriptase inhibitors

H. Gendelman, S. Swindells, 1996 .

Enhancement of NMDA Receptor-Mediated Excitatory Postsynaptic Currents by gp120-Treated Macrophages: Implications for HIV-1-Associated Neuropathology

H. Xiong, H. Gendelman, Jianuo Liu, 2013, Journal of Neuroimmune Pharmacology.

Glycogen Synthase Kinase 3 Beta (GSK-3β) as a Therapeutic Target in NeuroAIDS

H. Gendelman, G. Schifitto, S. Dewhurst, 2007, Journal of Neuroimmune Pharmacology.

Human immunodeficiency virus type 1 infection of neural xenografts.

H. Gendelman, R. Reichman, T. Cvetkovich, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Human polyomavirus, JC virus, and progressive multifocal leukoencephalopathy.

S. Lipton, I. Grant, H. Gendelman, 2005 .

A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders

H. Gendelman, R. Mosley, 2015, Journal of Neuroimmune Pharmacology.

Predictive biomarkers for cognitive decline during progressive HIV infection

H. Gendelman, 2019, EBioMedicine.

An open-label multiyear study of sargramostim-treated Parkinson’s disease patients examining drug safety, tolerability, and immune biomarkers from limited case numbers

H. Gendelman, R. Mosley, Pamela Santamaria, 2023, Translational Neurodegeneration.

Inhibition of long‐term potentiation by interleukin‐8: Implications for human immunodeficiency virus‐1‐associated dementia

H. Xiong, H. Gendelman, Jialin C. Zheng, 2003, Journal of neuroscience research.

Macrophages/microglia and the pathophysiology of CNS injuries in AIDS

H. Gendelman, M. Tardieu, 1994, Journal of leukocyte biology.

CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice

H. Gendelman, K. Khalili, T. Burdo, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Exonic Disruption Facilitates Antiviral CRISPR-Cas9 Activity for Multistrain HIV-1 Elimination

H. Gendelman, J. McMillan, M. Hasan, 2021, bioRxiv.

Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders

H. Gendelman, C. Dong, H. Gelbard, 2009, Journal of Neuroimmunology.

BL-1023 improves behavior and neuronal survival in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice

H. Gendelman, J. McMillan, R. Mosley, 2011, Neuroscience.

Current concepts in HIV neuropathogenesis: neuronal injury, white matter disease, and neurotrophic factors.

S. Lipton, E. Masliah, I. Grant, 2011 .

HIV‐1‐infected and/or immune activated macrophages regulate astrocyte SDF‐1 production through IL‐1β

H. Gendelman, Jialin C. Zheng, Hui Peng, 2006, Glia.

a Murine Model of HIV-1 Encephalitis Virus-Infected Human Brain Macrophages in Generation of Cytotoxic T Cells Against

H. Gendelman, D. Munn, Y. Persidsky, 2013 .

Expression of pro‐ and anti‐apoptosis gene products in brains from paediatric patients with HIV‐1 encephalitis

H. Gendelman, John Calvin Reed, S. Krajewski, 1997, Neuropathology and applied neurobiology.

Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis

H. Gendelman, A. Ghorpade, Y. Persidsky, 2011, Journal of NeuroVirology.

Experimental Model Systems for Studies of HIV Encephalitis

H. Gendelman, M. Jett, H. Nottet, 1995 .

AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice.

H. Gendelman, R. Ransohoff, W. Klein, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress

G. Siuzdak, H. Gendelman, J. McMillan, 2018, Molecular Neurobiology.

Immunology of HIV-1.

S. Lipton, I. Grant, H. Gendelman, 2005 .

Advances in long-acting slow effective release antiretroviral therapies for treatment and prevention of HIV infection.

Md Mahmudul Hasan, H. Gendelman, V. Soriano, 2023, Advanced drug delivery reviews.

Changes in the plasma proteome follows chronic opiate administration in simian immunodeficiency virus infected rhesus macaques.

H. Gendelman, H. Fox, P. Ciborowski, 2012, Drug and alcohol dependence.

Neuropathological aspects of HIV-1 infection in children.

S. Lipton, I. Grant, H. Gendelman, 2005 .

T cells and Parkinson's disease

H. Gendelman, R. Mosley, 2017, The Lancet Neurology.

Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease

H. Gendelman, P. Ciborowski, Y. Enose, 2004, Journal of Neuroimmunology.

Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24–25, 2008

I. Grant, H. Gendelman, E. Major, 2009, Journal of Neuroimmune Pharmacology.

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

H. Gendelman, J. McMillan, A. Kabanov, 2012, International journal of nanomedicine.

Humanized Mice for Studies of HIV-1 Persistence and Elimination

H. Gendelman, P. Dash, S. Gorantla, 2023, Pathogens.

Neurological and Neuropsychiatric Manifestations of HIV-1 Infection

S. Lipton, H. Gendelman, S. Swindells, 1998 .

Resource Brain Region Mapping Using Global Metabolomics

G. Siuzdak, A. Epstein, H. Gendelman, 2014 .

Postinfectious Encephalomyelitis

H. Gendelman, D. Griffin, Richard T. Johnson, 1985 .

Valproic acid adjunctive therapy for HIV-associated cognitive impairment: A first report

H. Gendelman, G. Schifitto, J. Zhong, 2006, Neurology.

A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.

M. Weinand, H. Gendelman, K. Kim, 1997, Journal of immunology.

Journal of Neuroimmunology: Editorial

H. Gendelman, J. Joseph, H. Fox, 2004, Journal of Neuroimmunology.

Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis.

M. Weinand, H. Gendelman, M. Stins, 1999, The American journal of pathology.

Quantitative 1H Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy in an Animal Model of Parkinson's Disease

Mariano G. Uberti, H. Gendelman, C. Destache, 2005, The Journal of Neuroscience.

Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium

H. Gendelman, D. Kolson, K. Jordan-Sciutto, 2014, Journal of Neuroimmune Pharmacology.

Opportunistic infections of the nervous system in AIDS.

S. Lipton, I. Grant, H. Gendelman, 2005 .

HIV-associated dementia: new insights into disease pathogenesis and therapeutic interventions.

H. Gendelman, S. Swindells, H. Gendelman, 1999, AIDS patient care and STDs.

Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease

H. Gendelman, L. Resnick, L. Epstein, 1992, The Journal of experimental medicine.

Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains

H. Gendelman, Weizhe Li, S. Gorantla, 2017, Disease Models & Mechanisms.

Oral antivirals for the prevention and treatment of SARS-CoV-2 infection.

H. Gendelman, V. Soriano, Benson J. Edagwa, 2022, AIDS reviews.

HIV-1 infection and AIDS: consequences for the central nervous system

M. Kaul, S. Lipton, H. Gendelman, 2005, Cell Death and Differentiation.

HIV-1 Infection in Macrophages of Exosomes and Microvesicles as Facilitators Biochemical and Biologic Characterization of

H. Gendelman, Irena Kadiu, P. Dash, 2012 .

HIV-1 transforms the monocyte plasma membrane proteome.

Howard E Gendelman, Pawel Ciborowski, M. Bukrinsky, 2009, Cellular immunology.

Evaluation of neurodevelopmental deficits in children with HIV-1 infection.

S. Lipton, I. Grant, H. Gendelman, 2005 .

Mononuclear phagocytes and the human immunodeficiency virus.

H. Gendelman, M. Meltzer, 1990, Current opinion in immunology.

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.

H. Gendelman, D. Munn, O. Takikawa, 2005, Blood.

Nanomedicine and Neurodegenerative Disorders

H. Gendelman, Ari S. Nowacek, J. McMillan, 2011 .

A model of nitric oxide induced α-synuclein misfolding in Parkinson's disease

H. Gendelman, T. Kiyota, R. Mosley, 2012, Neuroscience Letters.

Pathways for Dolutegravir Transformation from a Daily Oral to a Once-a-Year Parenteral Medicine

H. Gendelman, J. McMillan, A. Dahan, 2022 .

Human immunodeficiency virus encephalitis in SCID mice.

H. Gendelman, L. Epstein, H. Gelbard, 1996, The American journal of pathology.

Methamphetamine-Associated Psychosis

Howard E. Gendelman, Ming Li, Rick A. Bevins, 2011, Journal of Neuroimmune Pharmacology.

Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis

H. Xiong, H. Gendelman, Y. Persidsky, 2003, Neuroscience.

Immune senescence in aged APP/PS1 mice

H. Gendelman, R. Mosley, Jatin Machhi, 2023, NeuroImmune pharmacology and therapeutics.

HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice

H. Gendelman, P. Dash, K. Bidasee, 2020, Scientific Reports.

Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients

H. Gendelman, G. Schifitto, S. Dewhurst, 2013, Journal of NeuroVirology.

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription

M. Sporn, J. Morrow, M. Beal, 2009, PloS one.

An interactive cluster heat map to visualize and explore multidimensional metabolomic data

G. Siuzdak, A. Epstein, H. Gendelman, 2015, Metabolomics.

An image warping technique for rodent brain MRI-histology registration based on thin-plate splines with landmark optimization

Yutong Liu, Mariano G. Uberti, Howard E. Gendelman, 2009, Medical Imaging.

A call for transparent reporting to optimize the predictive value of preclinical research

S. Lazic, O. Steward, Story C. Landis, 2012, Nature.

Neurodegenerative disorders and nanoformulated drug development.

H. Gendelman, Ari S. Nowacek, L. M. Kosloski, 2009, Nanomedicine.

Neuropharmacologic Approaches to Restore the Brain’s Microenvironment

H. Gendelman, Weizhe Li, Yuanan Lu, 2016, Journal of Neuroimmune Pharmacology.

Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease

K. Hasan, H. Gendelman, Irena Kadiu, 2006, Clinical Neuroscience Research.

Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease

K. Hasan, H. Gendelman, M. Boska, 2007, Neurobiology of Disease.

Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFα inhibitor in SCID mice with HIV-1 encephalitis

H. Gendelman, Y. Persidsky, H. Gendelman, 2001, Journal of Neuroimmunology.

Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis

H. Gendelman, Jianuo Liu, R. Mosley, 2011, Journal of Neuroimmunology.

Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders

H. Gendelman, C. Dong, H. Gelbard, 2009, Journal of Neuroimmunology.

Hiv-1-associated Neurodegeneration Regulatory T Cells in a Murine Model of + Cd25 + Neuromodulatory Activities of Cd4

H. Gendelman, Jianuo Liu, R. Mosley, 2022 .

Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines.

Anup D. Sharma, H. Gendelman, B. Narasimhan, 2015, Nanomedicine : nanotechnology, biology, and medicine.

The promise of nanoneuromedicine: An editorial

H. Gendelman, T. Bronich, A. Pai, 2016 .

HIV and the Macrophage: From Cell Reservoirs to Drug Delivery to Viral Eradication

H. Gendelman, Jonathan Herskovitz, 2018, Journal of Neuroimmune Pharmacology.

A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes [published erratum appears in J Exp Med 1991 Jan 1;173(1):277]

H. Gendelman, L. Baca, Monte S. Meltzer, 1990, The Journal of experimental medicine.

Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages

H. Gendelman, H. Gelbard, S. Gorantla, 2019, Journal of Neuroimmune Pharmacology.

Models of NeuroAIDS Neuroprotective Activities of CEP-1347 in

H. Gendelman, G. Schifitto, H. Gelbard, 2009 .

HIV-1 neuroimmunity in the era of antiretroviral therapy

Stephanie D. Kraft-Terry, H. Gendelman, S. Buch, 2010, Neurobiology of Disease.

Proteomic analysis of mesenchymal to Schwann cell transdifferentiation.

Anup D. Sharma, H. Gendelman, S. Mallapragada, 2017, Journal of proteomics.

Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery.

H. Gendelman, M. Boska, R. Mosley, 2006, Blood.

Model systems for assessing cognitive function: implications for HIV-1 infection and drugs of abuse.

H. Xiong, H. Gendelman, W. Zink, 2001, Advances in experimental medicine and biology.

Delivery of gene editing therapeutics.

H. Gendelman, Neha Bajwa, J. Madan, 2023, Nanomedicine : nanotechnology, biology, and medicine.

Commentary: Animal Models of NeuroAIDS

H. Gendelman, H. Fox, 2012, Journal of Neuroimmune Pharmacology.

Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders?

H. Gendelman, S. Gorantla, L. Poluektova, 2012, Journal of Neuroimmune Pharmacology.

The blood-brain barrier: A defensive shield or a perpetrator of microbial invasion?

H. Gendelman, W. Hickey, J. Rappaport, 1999 .

Murine Motor and Behavior Functional Evaluations for Acute 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Intoxication

H. Gendelman, R. Mosley, Jessica A. L. Hutter-Saunders, 2011, Journal of Neuroimmune Pharmacology.

Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

H. Gendelman, K. Khalili, J. Gordon, 2016, Gene Therapy.

The neuropathogenesis of the AIDS dementia complex.

H. Gendelman, M. Stins, A. Ghorpade, 1997, AIDS.

Quiet connections: Reduced fronto‐temporal connectivity in nondemented Parkinson's Disease during working memory encoding

Alex I. Wiesman, Timothy J. McDermott, T. Wilson, 2016, Human brain mapping.

Long-acting dolutegravir formulations prevent neurodevelopmental impairments in a mouse model

H. Gendelman, B. Sajja, Benson J. Edagwa, 2023, Frontiers in pharmacology.

Erratum: Molecular characterization of a polymerase mutant human immunodeficiency virus (Virology (1987) 160:2 (323-329))

H. Gendelman, S. Venkatesan, A. Adachi, 1992 .

Amyloid-β specific regulatory T cells attenuate Alzheimer’s disease pathobiology in APP/PS1 mice

H. Gendelman, R. Mosley, Jatin Machhi, 2023, Molecular neurodegeneration.

HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.

H. Xiong, H. Gendelman, Y. Persidsky, 2000, Journal of neurovirology.

Accelerated Neuroimmune Dysfunction in Aged HIV-1-Infected Humanized Mice

H. Gendelman, S. Gorantla, L. Poluektova, 2024, Pharmaceuticals.

Neuroprotective mushrooms

H. Gendelman, R. Mosley, M. M. Abdelmoaty, 2024, NeuroImmune Pharmacology and Therapeutics.

The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis.

H. Gendelman, D. Mcclernon, M. Zelivyanskaya, 2001, Virology.

Interferon-(cid:2) and Tumor Necrosis Factor-(cid:3) Regulate Amyloid-(cid:4) Plaque Deposition and (cid:4) -Secretase Expression in Swedish Mutant APP Transgenic Mice

James L. Buescher, Shannon M Walsh, H. Gendelman, 2022 .

Development of a porous layer-by-layer microsphere with Development of a porous layer-by-layer microsphere with branched aliphatic hydrocarbon porogens branched aliphatic hydrocarbon porogens

H. Gendelman, B. Kevadiya, Farah Shahjin, 2023 .