I. Wilson

发表

H. Westerhoff, J. Snoep, S. Geenen, 2012, Archives of Toxicology.

Quantitative structure-metabolism relationships for substituted benzoic acids in the rabbit: prediction of urinary excretion of glycine and glucuronide conjugates.

C. Beddell, I. Wilson, B. Cupid, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice.

M. Rantalainen, I. Wilson, J. Trygg, 2006, Journal of proteome research.

Liquid chromatography-mass spectrometry based global metabolite profiling: a review.

E. Want, I. Wilson, G. Theodoridis, 2012, Analytica chimica acta.

The challenges of modeling mammalian biocomplexity

Elaine Holmes, John C Lindon, Jeremy K Nicholson, 2004, Nature Biotechnology.

Hyphenated MS-based targeted approaches in metabolomics.

I. Wilson, G. Theodoridis, I. Wilson, 2017, The Analyst.

Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometry

Ian D. Wilson, Jeremy K. Nicholson, I. Wilson, 2016, Journal of chromatography. A.

Pharmacometabonomics as an effector for personalized medicine.

John C Lindon, Jeremy K Nicholson, Ian D Wilson, 2011, Pharmacogenomics.

HIGH RESOLUTION PROTON MAGNETIC RESONANCE SPECTROSCOPY OF BIOLOGICAL FLUIDS

Ian D. Wilson, Jeremy K. Nicholson, I. Wilson, 1989 .

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development.

J C Lindon, I. Wilson, J. Lindon, 2000, Journal of chromatography. B, Biomedical sciences and applications.

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy.

John C Lindon, Jeremy K Nicholson, Muireann Coen, 2003, Chemical research in toxicology.

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

I. Wilson, J. Nicholson, 2003, Nature Reviews Drug Discovery.

A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects.

Anthony F. P. Nash, I. Wilson, E. Lenz, 2003, Journal of pharmaceutical and biomedical analysis.

Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects.

I. Wilson, E. Lenz, J. Bright, 2004, Journal of pharmaceutical and biomedical analysis.

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse.

John C Lindon, Jeremy K Nicholson, Muireann Coen, 2004, Journal of pharmaceutical and biomedical analysis.

Metabolism by conjugation appears to confer resistance to paracetamol (acetaminophen) hepatotoxicity in the cynomolgus monkey

I. Wilson, E. Lenz, Hong Yu, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Rapid and noninvasive metabonomic characterization of inflammatory bowel disease.

I. Wilson, E. Holmes, F. Shanahan, 2007, Journal of proteome research.

An NMR‐based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

I. Wilson, J. Nicholson, E. Holmes, 2000, FEBS letters.

A combined (1)H NMR and HPLC-MS-based metabonomic study of urine from obese (fa/fa) Zucker and normal Wistar-derived rats.

I. Wilson, R. Plumb, E. Lenz, 2005, Journal of pharmaceutical and biomedical analysis.

Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice.

I. Wilson, J. Nicholson, Claire L Gavaghan McKee, 2006, Journal of proteome research.

Hippurate: the natural history of a mammalian-microbial cometabolite.

I. Wilson, J. Nicholson, E. Holmes, 2013, Journal of proteome research.

Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: application to human urine.

I. Wilson, G. Theodoridis, H. Gika, 2007, Journal of proteome research.

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum.

Joshua D. Knowles, D. Kell, W. Dunn, 2009, Analytical chemistry.

A QC approach to the determination of day-to-day reproducibility and robustness of LC-MS methods for global metabolite profiling in metabonomics/metabolomics.

I. Wilson, G. Theodoridis, H. Gika, 2012, Bioanalysis.

Gut microorganisms, mammalian metabolism and personalized health care

I. Wilson, J. Nicholson, E. Holmes, 2005, Nature Reviews Microbiology.

Liquid chromatography and ultra-performance liquid chromatography-mass spectrometry fingerprinting of human urine: sample stability under different handling and storage conditions for metabonomics studies.

I. Wilson, G. Theodoridis, H. Gika, 2008, Journal of chromatography. A.

Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies.

I. Wilson, G. Theodoridis, H. Gika, 2011, Mass spectrometry reviews.

High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies.

I. Wilson, J. Nicholson, R. Plumb, 2005, Journal of proteome research.

LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics

I. Wilson, G. Theodoridis, H. Gika, 2008 .

Does the mass spectrometer define the marker? A comparison of global metabolite profiling data generated simultaneously via UPLC-MS on two different mass spectrometers.

I. Wilson, G. Theodoridis, H. Gika, 2010, Analytical chemistry.

A pragmatic and readily implemented quality control strategy for HPLC-MS and GC-MS-based metabonomic analysis.

I. Wilson, H. Major, R. Plumb, 2006, The Analyst.

Evaluation of the repeatability of ultra-performance liquid chromatography-TOF-MS for global metabolic profiling of human urine samples.

I. Wilson, G. Theodoridis, H. Gika, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A mathematical modelling approach to assessing the reliability of biomarkers of glutathione metabolism.

H. Nijhout, M. Reed, H. Westerhoff, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR

I. Wilson, J. Lindon, J. Nicholson, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation.

I. Wilson, J. Nicholson, R. Plumb, 2006, Rapid communications in mass spectrometry : RCM.

Predicting drug metabolism: experiment and/or computation?

Dieter Lang, Gisbert Schneider, Robert C. Glen, 2015, Nature Reviews Drug Discovery.

HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies.

E. Want, I. Wilson, J. Lindon, 2011, Analytical chemistry.

Metabolic Phenotyping in Health and Disease

Ian D. Wilson, Jeremy K. Nicholson, Elaine Holmes, 2008, Cell.

1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies.

Robert S Plumb, Jeremy K Nicholson, Ian D Wilson, 2008, Analytical chemistry.

Analytical strategies in metabonomics.

Ian D Wilson, I. Wilson, E. Lenz, 2007, Journal of proteome research.

Direct analysis of pharmaceutical drug formulations using ion mobility spectrometry/quadrupole-time-of-flight mass spectrometry combined with desorption electrospray ionization.

C. Creaser, I. Wilson, D. Weston, 2005, Analytical chemistry.

Enhanced analyte detection using in-source fragmentation of field asymmetric waveform ion mobility spectrometry-selected ions in combination with time-of-flight mass spectrometry.

C. Creaser, I. Wilson, D. Weston, 2012, Analytical chemistry.

Differential Effect of Troglitazone on the Human Bile Acid Transporters, MRP2 and BSEP, in the PXB Hepatic Chimeric Mouse

I. Wilson, Y. Morikawa, J. Foster, 2012, Toxicologic pathology.

Summary recommendations for standardization and reporting of metabolic analyses

Nigel W. Hardy, Jake T. M. Pearce, Stephen J. Bruce, 2005, Nature Biotechnology.

Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: Measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS

I. Wilson, M. Godejohann, J. Nicholson, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat.

I. Wilson, J. Lindon, J. Nicholson, 1999, Journal of pharmaceutical and biomedical analysis.

NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat.

I. Wilson, S. Caddick, J. Lindon, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS‐DA

I. Wilson, J. Nicholson, C. Gavaghan, 2002, FEBS letters.

Quantitative structure-metabolism relationships (QSMR) using computational chemistry: pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat.

E Holmes, J C Lindon, I. Wilson, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

Comparison of extraction of a beta-blocker from plasma onto a molecularly imprinted polymer with liquid-liquid extraction and solid phase extraction methods.

I. Wilson, P. Martin, G. Jones, 2004, Journal of pharmaceutical and biomedical analysis.

Ethyl glucoside in human urine following dietary exposure: detection by 1H NMR spectroscopy as a result of metabonomic screening of humans.

Jeremiah Stamler, Elaine Holmes, Paul Elliott, 2004, The Analyst.

Ion-Pairing Chromatography and Amine Derivatization Provide Complementary Approaches for the Targeted LC-MS Analysis of the Polar Metabolome

E. Want, I. Wilson, J. Bundy, 2021, Journal of proteome research.

Addressing the challenge of limited sample volumes in in vitro studies with capillary-scale microfluidic LC-MS/MS.

I. Wilson, J. Nicholson, R. Plumb, 2011, Bioanalysis.

Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine.

J P Shockcor, J C Lindon, I. Wilson, 1996, Analytical chemistry.

Metabonomic analysis of mouse urine by liquid-chromatography-time of flight mass spectrometry (LC-TOFMS): detection of strain, diurnal and gender differences.

Ian D Wilson, I. Wilson, R. Plumb, 2003, The Analyst.

A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice.

Jennifer H Granger, Robert S Plumb, Ian D Wilson, 2005, The Analyst.

High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma.

Caroline H. Johnson, I. Wilson, J. Lindon, 2010, Rapid communications in mass spectrometry : RCM.

Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategy.

Alison J. Foster, H. Westerhoff, J. Snoep, 2013, Biochimica et biophysica acta.

Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats.

Hans V Westerhoff, James W T Yates, Ian D Wilson, 2013, Integrative biology : quantitative biosciences from nano to macro.

In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs.

Yan Li, Hugues Dolgos, R. A. Thompson, 2012, Chemical research in toxicology.

Rapid determination of the pharmacokinetics and metabolic fate of gefitinib in the mouse using a combination of UPLC/MS/MS, UPLC/QToF/MS, and ion mobility (IM)-enabled UPLC/QToF/MS

I. Wilson, R. Plumb, L. Gethings, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat

I. Wilson, J. Nicholson, M. Coen, 2020, Chromatographia.

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine.

I. Wilson, J. Langridge, J. Vissers, 2019, Journal of chromatography. A.

Rapid profiling method for the analysis of lipids in human plasma using ion mobility enabled-reversed phase-ultra high performance liquid chromatography/mass spectrometry.

I. Wilson, R. Plumb, G. Isaac, 2020, Journal of chromatography. A.

Supercritical Fluid Chromatography for Metabolic Phenotyping: Potential and Applications

I. Wilson, R. Plumb, 2019, The Handbook of Metabolic Phenotyping.

Metabolic phenotyping (metabonomics/metabolomics) by liquid chromatography-mass spectrometry

I. Wilson, G. Theodoridis, H. Gika, 2017 .

Solid phase extraction methodology for UPLC‐MS based metabolic profiling of urine samples

I. Wilson, D. Palachanis, G. Theodoridis, 2015, Electrophoresis.

Strategies and Techniques for the Identification of Endogenous and Xenobiotic Metabolites Detected in Metabonomic Studies

I. Wilson, J. Shockcor, 2005 .

1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat.

I. Wilson, S. Caddick, J. Lindon, 1995, Biochemical pharmacology.

Quantitative structure―chromatography relationships : prediction of TLC behavior using theoretically derived molecular properties

Robert C. Glen, Ian D. Wilson, John C. Lindon, 1991 .

5.43 – Metabonomics

I. Wilson, 2007 .

The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry.

I. Wilson, R. Plumb, J. Granger, 2006, Rapid communications in mass spectrometry : RCM.

Plasma metabolic profiling reveals age-dependency of systemic effects of green tea polyphenols in mice with and without prostate cancer.

Donald J L Jones, I. Wilson, H. Keun, 2010, Molecular bioSystems.

Multiple hyphenation of liquid chromatography with nuclear magnetic resonance spectroscopy, mass spectrometry and beyond.

I. Wilson, Ian D. Wilson, 2000, Journal of chromatography. A.

Spectroscopic characterisation and identification of ecdysteroids using high-performance liquid chromatography combined with on-line UV--diode array, FT-infrared and 1H-nuclear magnetic resonance spectroscopy and time of flight mass spectrometry.

I. Wilson, E. Lenz, A. Sage, 2001, Journal of chromatography. A.

Profiling and biomarker identification in plasma from different Zucker rat strains via high mass accuracy multistage mass spectrometric analysis using liquid chromatography/mass spectrometry with a quadrupole ion trap-time of flight mass spectrometer.

I. Wilson, G. Theodoridis, H. Gika, 2008, Rapid communications in mass spectrometry : RCM.

A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats

I. Wilson, J. Nicholson, M. Coen, 2020, Journal of proteome research.

Quality Control and Validation Issues in LC-MS Metabolomics.

I. Wilson, G. Theodoridis, H. Gika, 2018, Methods in molecular biology.

High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure.

I. Wilson, M. Mcphail, J. Nicholson, 2017, Analytical chemistry.

High-Throughput Microbore UPLC-MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies.

I. Wilson, J. Nicholson, Matthew R. Lewis, 2015, Journal of proteome research.

Identification of non-steroidal anti-inflammatory drugs and their metabolites in solid phase extracts of human urine using capillary electrophoresis–mass spectrometry

I. Wilson, A. Ashcroft, H. Major, 1995 .

Selective deuterium exchange during superheated heavy water chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry of sulfonamides.

R. Smith, I. Wilson, B. Wright, 2000, Journal of chromatography. A.

Superheated water chromatography-nuclear magnetic resonance spectroscopy and mass spectrometry of vitamins.

I. Wilson, E. Lenz, Roger M. Smith, 2004, Journal of Pharmaceutical and Biomedical Analysis.

High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline.

I. Wilson, J. Lindon, J. Nicholson, 2000, The Analyst.

Application and elution conditions for the selective elution of analytes from molecular imprinted polymers after extraction from aqueous samples: Application to β-blockers

Paul D. Martin, I. Wilson, G. Jones, 2000 .

Real-time reaction monitoring using ion mobility-mass spectrometry.

C. Creaser, I. Wilson, A. Bristow, 2011, The Analyst.

Comparison of normal and reversed-phase solid phase extraction methods for extraction of beta-blockers from plasma using molecularly imprinted polymers.

Paul D. Martin, I. Wilson, G. Jones, 2003, The Analyst.

Utility of the HRN™ (hepatic cytochrome P450 reductase null) mice for investigating mechanisms of liver toxicity of carboxylic-acid-containing drugs

I. Wilson, S. Sarda, G. Kenna, 2014 .

Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions.

I. Wilson, S. Hansen, J. Lindon, 1996, Journal of chromatography. B, Biomedical applications.

High-performance liquid chromatography directly coupled to 19F and 1H NMR for the analysis of mixtures of isomeric ester glucuronide conjugates of trifluoromethylbenzoic acids

John W. Gilbert, I. Wilson, J. Lindon, 1996 .

Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR

I. Wilson, J. Lindon, J. Nicholson, 1995 .

The metabolism of [14C]N-ethoxycarbonyl-3-morpholinosydnonimine (molsidomine) in laboratory animals.

I. Wilson, H. Illing, I D Wilson, 1986, Xenobiotica; the fate of foreign compounds in biological systems.

Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry.

I. Wilson, R. Weaver, Christopher J. Smith, 2011, Rapid communications in mass spectrometry : RCM.

Metabolite profiles from dried blood spots for metabonomic studies using UPLC combined with orthogonal acceleration ToF-MS: effects of different papers and sample storage stability.

I. Wilson, G. Theodoridis, Christopher J. Smith, 2011, Bioanalysis.

Chapter 20 Drugs

I. Wilson, 2004 .

In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid

I. Wilson, J. G. Kenna, S. Stahl, 2013, Archives of Toxicology.

Capillary ultra performance liquid chromatography-tandem mass spectrometry analysis of tienilic acid metabolites in urine following intravenous administration to the rat.

I. Wilson, M. Coen, R. Plumb, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A validated UPLC-MS/MS assay for the quantification of amino acids and biogenic amines in rat urine.

I. Wilson, J. Nicholson, R. Plumb, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis.

G. Kollias, I. Wilson, M. Firth, 2016, Journal of proteome research.

Global metabolic profiling in health and disease

I. Wilson, G. Theodoridis, A. Nicholls, 2014 .

The role of gut microbiota in drug response.

I. Wilson, J. Nicholson, 2009, Current pharmaceutical design.

UNDERSTANDING DRUG METABOLISM IN HUMANS

I. Wilson, L. Weidolf, 2016 .

Comparison of metabolomic profiles obtained using chemical ionization and electron ionization MS in exhaled breath.

I. Wilson, C. L. Thomas, M. Turner, 2011, Bioanalysis.

Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships.

I. Wilson, J. Lindon, S. Richards, 2020, Organic & biomolecular chemistry.

Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy

David B. Darr, I. Wilson, J. Roach, 2020, Proceedings of the National Academy of Sciences.

Considerations in the design of clinical and epidemiological metabolic phenotyping studies

I. Wilson, G. Theodoridis, H. Gika, 2014 .

Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine.

I. Wilson, L. Tseng, J. Lindon, 1998, The Analyst.

Direct characterization of drug glucuronide isomers in human urine by HPLC-NMR spectroscopy: application to the positional isomers of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid glucuronide.

I. Wilson, M. Hofmann, M. Spraul, 1996, Analytical chemistry.

A metabonomic study of strain- and age-related differences in the Zucker rat.

I. Wilson, R. Plumb, E. Lenz, 2007, Rapid communications in mass spectrometry : RCM.

High-Throughput UHPLC/MS/MS-Based Metabolic Profiling Using a Vacuum Jacketed Column.

I. Wilson, R. Plumb, P. Rainville, 2021, Analytical chemistry.

Direct analysis of pharmaceutical formulations from non-bonded reversed-phase thin-layer chromatography plates by desorption electrospray ionisation ion mobility mass spectrometry.

C. Creaser, I. Wilson, J. C. Reynolds, 2009, Rapid communications in mass spectrometry : RCM.

Directly coupled liquid chromatography with inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the identification of drug metabolites in urine: application to diclofenac using chlorine and sulfur detection.

I. Wilson, J. Nicholson, J. Castro-Pérez, 2000, Rapid communications in mass spectrometry : RCM.

Application of Capillary Electrophoresis–Mass Spectrometry to the Analysis of Urine Samples From Animals and Man Containing Paracetamol and Phenacetin and Their Metabolites

I. Wilson, J. Nicholson, A. Ashcroft, 1997 .

Advances in Mass Spectrometry Within Drug Discovery

I. Wilson, J. Wingfield, 2016, Journal of biomolecular screening.

Extraction methods for the removal of phospholipids and other endogenous material from a biological fluid.

I. Wilson, G. Theodoridis, F. Michopoulos, 2011, Bioanalysis.

High-performance liquid chromatography linked to inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the simultaneous detection and identification of metabolites of 2-bromo-4-trifluoromethyl.

I. Wilson, J. Lindon, J. Nicholson, 2001, Analytical chemistry.

Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid.

Alison J. Foster, I. Wilson, J. G. Kenna, 2017, Toxicology research.

Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice

Alison J. Foster, I. Wilson, J. G. Kenna, 2016, Archives of Toxicology.

Metabonomic Studies Comparing Capillary and Conventional HPLC-oa-TOF MS for the Analysis of Urine from Zucker Obese Rats

I. Wilson, R. Plumb, J. Castro-Pérez, 2005 .

High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat.

I. Wilson, S. Caddick, J. Lindon, 1995, Biochemical pharmacology.

A comparison of the metabolism of midazolam in C57BL/6J and hepatic reductase null (HRN) mice.

I. Wilson, M. Hutchison, R. Gallagher, 2014, Biochemical pharmacology.

The Modulation of Drug Efficacy and Toxicity by the Gut Microbiome

I. Wilson, J. Nicholson, 2015 .

Preclinical Drug Efficacy and Safety Using NMR Spectroscopy

I. Wilson, M. Coen, 2015 .

Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure

I. Wilson, R. Jalan, M. Coen, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: applications to serum, urine and tissue extracts.

I. Wilson, T. Dunkley, G. Theodoridis, 2014, Journal of chromatography. A.

Metabolic Profiling: Status, Challenges, and Perspective.

I. Wilson, G. Theodoridis, H. Gika, 2018, Methods in molecular biology.

NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide.

I. Wilson, J. Lindon, J. Nicholson, 2006, Journal of pharmaceutical and biomedical analysis.

Investigation of chronic alcohol consumption in rodents via ultra-high-performance liquid chromatography-mass spectrometry based metabolite profiling.

I. Wilson, N. Kaplowitz, G. Theodoridis, 2012, Journal of chromatography. A.

Analytical methodology for clinical metabolic profiling: sample preparation, sample analysis and statistical evaluation

I. Wilson, G. Theodoridis, H. Gika, 2014 .

Quantification of urinary mevalonic acid as a biomarker of HMG-CoA reductase activity by a novel translational LC-MS/MS method.

M. Pirmohamed, I. Wilson, M. Coen, 2014, Bioanalysis.

Sample Preparation for Biomedical and Environmental Analysis

I. Wilson, D. Stevenson, 1994, Chromatographic Society Symposium Series.

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective.

I. Wilson, A. Boobis, J. Nicholson, 2018, Toxicology research.

The Role of Nuclear Magnetic Resonance Spectroscopy in Drug Metabolism

I. Wilson, J. Lindon, J. Nicholson, 1999 .

On-flow identification of metabolites of paracetamol from human urine using directly coupled CZE–NMR and CEC–NMR spectroscopy

I. Wilson, L. Tseng, J. Lindon, 1998 .

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man.

I. Wilson, J. Lindon, J. Nicholson, 1997, Journal of pharmaceutical and biomedical analysis.

Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra.

I. Wilson, M. Spraul, J. Lindon, 1994, Journal of pharmaceutical and biomedical analysis.

Induction of 5-oxoprolinuria in the rat following chronic feeding with N-acetyl 4-aminophenol (paracetamol).

I. Wilson, J. Nicholson, A. Mclean, 1993, Biochemical pharmacology.

Analysis of biological fluids by high-field nuclear magnetic resonance spectroscopy

I. Wilson, J. Nicholson, K. E. Wade, 1989 .

APPLICATION OF HIGH RESOLUTION H-NMR SPECTROSCOPY TO THE DETECTION OF PENICILLAMINE AND ITS METABOLITES IN HUMAN URINE

I. Wilson, J. Nicholson, J. A. Walshe, 1988 .

Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine.

I. Wilson, J. Nicholson, 1988, Journal of pharmaceutical and biomedical analysis.

Proton magnetic resonance spectroscopy of human urine: Excretion of 1-(3'-carboxypropyl)-3,7-dimethylxanthine by man after dosing with oxpentifylline.

I. Wilson, J. Nicholson, I. Ismail, 1987, Journal of pharmaceutical and biomedical analysis.

Detection, Identification and Quantitative Analysis of Drugs by 1H NMR

I. Wilson, I. Ismail, 1986 .

A rapid method for the isolation and identification of drug metabolites from human urine using solid phase extraction and proton NMR spectroscopy.

I. Wilson, I. Ismail, 1986, Journal of pharmaceutical and biomedical analysis.

UHPLC-MS-Based Lipidomic and Metabonomic Investigation of the Metabolic Phenotypes of Wild Type and Hepatic CYP Reductase Null (HRN) Mice.

I. Wilson, R. Plumb, L. Gethings, 2020, Journal of pharmaceutical and biomedical analysis.

1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat.

I. Wilson, J. Lindon, J. Nicholson, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

Nuclear magnetic resonance and high-performance liquid chromatography-nuclear magnetic resonance studies on the toxicity and metabolism of ifosfamide.

I. Wilson, J. Nicholson, J. Lindon, 1996, Therapeutic drug monitoring.

Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies.

I. Wilson, J. Nicholson, R. Plumb, 2016, Analytical chemistry.

A proton magnetic resonance study of the metabolism of N-methylformamide in the rat.

I. Wilson, J. Nicholson, J. Timbrell, 1986, Drug metabolism and disposition: the biological fate of chemicals.

Hype and hypernation : multiple hyphenation of column liquid chromatography and spectroscopy

I. Wilson, U. Brinkman, 2007 .

HPLC‐NMR Spectroscopy

I. Wilson, 2011 .

Reversed-phase high-performance liquid chromatography combined with on-line UV diode array, FT infrared, and 1H nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry: application to a mixture of nonsteroidal antiinflammatory drugs.

I. Wilson, E. Lenz, A. Sage, 2000, Analytical chemistry.

High-Performance Liquid Chromatography On-Line Coupled to High-Field NMR and Mass Spectrometry for Structure Elucidation of Constituents of Hypericum perforatum L.

I. Wilson, S. Hansen, I. Bjørnsdottir, 1999 .

Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS

I. Wilson, J. Lindon, J. Nicholson, 2000, Xenobiotica; the fate of foreign compounds in biological systems.

Size-exclusion chromatography with on-line ultraviolet, proton nuclear magnetic resonance and mass spectrometric detection and on-line collection for off-line Fourier transform infrared spectroscopy.

I. Wilson, B. Wright, D. Louden, 1999, Journal of Chromatography A.

Application of inductively coupled plasma mass spectrometry and high-performance liquid chromatography--with parallel electrospray mass spectrometry to the investigation of the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids in the rat.

I. Wilson, J. Nicholson, B. Jensen, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High temperature reversed-phase HPLC using deuterium oxide as a mobile phase for the separation of model pharmaceuticals with multiple on-line spectroscopic analysis (UV, IR, 1H-NMR and MS)

I. Wilson, E. Lenz, D. Louden, 2001 .

HPLC analysis of ecdysteroids in plant extracts using superheated deuterium oxide with multiple on-line spectroscopic analysis (UV, IR, 1H NMR, and MS).

I. Wilson, E. Lenz, R. Lafont, 2002, Analytical chemistry.

High performance liquid chromatography coupled to nuclear magnetic resonance spectroscopy and mass spectrometry applied to plant products: Identification of ecdysteroids fromSilene otites

E. Morgan, I. Wilson, J. Nicholson, 1999 .

Application of directly coupled high-performance liquid chromatography-nuclear magnetic resonance-mass spectrometry to the detection and characterisation of the metabolites of 2-bromo-4-trifluoromethylaniline in rat urine

I. Wilson, M. Hofmann, M. Spraul, 1997 .

Size exclusion chromatography with UV detection coupled to on-line 1H-NMR and on-line collection via a dedicated interface for subsequent off-line FT-IR

I. Wilson, B. Wright, D. Louden, 1999 .

High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICMPS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine

I. Wilson, J. Lindon, J. Nicholson, 2002 .

Application of directly coupled HPLC-NMR-MS/MS to the identification of metabolites of 5-trifluoromethylpyridone (2-hydroxy-5-trifluoromethylpyridine) in hydroponically grown plants.

I. Wilson, J. Lindon, J. Nicholson, 2000, Journal of agricultural and food chemistry.

Superheated Heavy Water as the Eluent for HPLC-NMR and HPLC-NMR-MS of Model Drugs

I. Wilson, Roger M. Smith, Stephen D. Taylor, 1999 .

Practical aspects of the use of high performance liquid chromatography combined with simultaneous nuclear magnetic resonance and mass spectrometry

I. Wilson, B. Wright, E. Clayton, 1998 .

Reversed-phase HPLC of polymer additives with multiple on-line spectroscopic analysis (UV, IR, 1H NMR and MS)

I. Wilson, E. Lenz, D. Louden, 2002, Analytical and bioanalytical chemistry.

High-performance liquid chromatography/inductively coupled plasma mass spectrometry and tandem mass spectrometry for the detection of carbon-containing compounds.

I. Wilson, F. Abou-Shakra, B. Jensen, 2004, Rapid communications in mass spectrometry : RCM.

A comparison of the quantitative methods for the analysis of the platinum-containing anticancer drug [cis-[amminedichloro(2-methylpyridine)]platinum(II)] (ZD0473) by HPLC coupled to either a triple quadrupole mass spectrometer or an inductively coupled plasma mass spectrometer.

I. Wilson, D. Roberts, T. Parry, 2003, Analytical chemistry.

The application of high performance liquid chromatography, coupled to nuclear magnetic resonance spectroscopy and mass spectrometry (HPLC-NMR-MS), to the characterisation of ibuprofen metabolites from human urine

I. Wilson, B. Wright, E. Clayton, 1998 .

19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4-trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling.

I. Wilson, J. Lindon, J. Nicholson, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

A metabolic phenotyping study in mice following acute and chronic exposures to ethanol.

I. Wilson, I. Taitzoglou, H. Gika, 2020, Journal of proteome research.

Liquid chromatographic methods combined with mass spectrometry in metabolomics

I. Wilson, G. Theodoridis, H. Gika, 2020, Proteomic and Metabolomic Approaches to Biomarker Discovery.

The metabolic fate and effects of 2-Bromophenol in male Sprague–Dawley rats

I. Wilson, J. Nicholson, E. Holmes, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Ultra high resolution SFC-MS as a high throughput platform for metabolic phenotyping: application to metabolic profiling of rat and dog bile.

I. Wilson, R. Plumb, N. Smith, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Phosphorus and sulfur metabonomic profiling of tissue and plasma obtained from tumour-bearing mice using ultra-performance liquid chromatography/inductively coupled plasma mass spectrometry.

I. Wilson, R. Wilkinson, C. Duckett, 2013, Rapid communications in mass spectrometry : RCM.

Sampling and Sample Preparation for LC-MS-Based Metabonomics/Metabolomics of Samples of Mammalian Origin

I. Wilson, G. Theodoridis, F. Michopoulos, 2012 .

Application of turbulent flow chromatography to the metabonomic analysis of human plasma: comparison with protein precipitation.

I. Wilson, G. Theodoridis, F. Michopoulos, 2010, Journal of separation science.

High temperature-ultra performance liquid chromatography-mass spectrometry for the metabonomic analysis of Zucker rat urine.

I. Wilson, G. Theodoridis, H. Gika, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Asymptomatic 5-oxoprolinuria detected by proton magnetic resonance spectroscopy.

I. Wilson, H. Parkes, J. Nicholson, 1993, Clinical chemistry.

Proton nuclear magnetic resonance of urine and bile from paracetamol dosed rats.

I. Wilson, J. Nicholson, T. Spurway, 1990, Journal of Pharmaceutical and Biomedical Analysis.

Investigation of the human metabolism of antipyrine using coupled liquid chromatography and nuclear magnetic resonance spectroscopy of urine.

I. Wilson, M. Hofmann, M. Spraul, 1993, Journal of chromatography.

Metabolite profiles from dried biofluid spots for metabonomic studies using UPLC combined with oaToF-MS.

I. Wilson, G. Theodoridis, Christopher J. Smith, 2010, Journal of proteome research.

Metabonomics in the Pharmaceutical Industry

I. Wilson, E. Lenz, Rebecca Williams, 2005 .

Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection

I. Wilson, J. Langridge, J. Nicholson, 2017, Analytica chimica acta.

Analysis of a ginger extract by high-performance liquid chromatography coupled to nuclear magnetic resonance spectroscopy using superheated deuterium oxide as the mobile phase.

I. Wilson, E. Lenz, Roger M. Smith, 2003, Journal of chromatography. A.

Superheated deuterium oxide reversed-phase chromatography coupled to proton nuclear magnetic resonance spectroscopy

I. Wilson, Roger M. Smith, B. Wright, 1998 .

Towards quality assurance and quality control in untargeted metabolomics studies

David M. Herrington, Richard D. Beger, Katrice A. Lippa, 2019, Metabolomics.

Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human In Vitro Systems

I. Wilson, T. Athersuch, C. Dilworth, 2018, Scientific Reports.

Pharmacokinetics and metabolism of midazolam in chimeric mice with humanised livers

I. Wilson, M. Hutchison, J. Swales, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

A workflow for the metabolomic/metabonomic investigation of exhaled breath using thermal desorption GC-MS.

I. Wilson, C. L. Thomas, M. Turner, 2012, Bioanalysis.

Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity.

I. Wilson, A N Phipps, J Stewart, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Use of Proton NMR for Determining Changes in Metabolite Excretion Profiles Induced by Dietary Changes in the Rat

I. Wilson, B. Wright, A. N. Phipps, 1997 .

Kinetic studies on the intramolecular acyl migration of β-1-O-acyl glucuronides: Application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy

I. Wilson, J. Lindon, J. Nicholson, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

High resolution 1H NMR spectroscopic studies of the composition of the haemolymph of crowd- and solitary-reared nymphs of the desert locust, Schistocerca gregaria.

I. Wilson, S. Simpson, E. Lenz, 2001, Insect biochemistry and molecular biology.

NMR spectroscopic studies on the haemolymph of the tobacco hornworm, Manduca sexta: assignment of 1H and 13C NMR spectra

I. Wilson, S. Reynolds, J. Lindon, 1999 .

β-hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy

I. Wilson, M. P. Harrison, D. Jones, 1991 .

Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites.

I. Wilson, M. Hofmann, M. Spraul, 1992, Journal of pharmaceutical and biomedical analysis.

Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy.

I. Wilson, J. Nicholson, F. Y. Ghauri, 1990, Journal of pharmaceutical and biomedical analysis.

Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine.

I. Wilson, J. Nicholson, 1987, Analytical chemistry.

2.7.5. HPLC/NMR and related hyphenated NMR methods

I. Wilson, J. Lindon, J. Nicholson, 2000 .

High resolution nuclear magnetic resonance spectroscopy of biological samples as an aid to drug development.

I. Wilson, J. Nicholson, I D Wilson, 1987, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

Diclofenac metabolism in the mouse: Novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry

I. Wilson, S. Sarda, T. Schulz-utermoehl, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

NMR spectroscopic and theoretical chemistry studies on the internal acyl migration reactions of the 1-O-acyl-beta-D-glucopyranuronate conjugates of 2-, 3-, and 4-(trifluoromethyl) benzoic acids.

I. Wilson, J. Lindon, J. Nicholson, 1996, Chemical research in toxicology.

Characterizing the metabolic effects of the selective inhibition of gut microbial β-glucuronidases in mice

I. Wilson, M. Redinbo, J. Nicholson, 2022, Scientific Reports.

Sensitive and Reproducible Mass Spectrometry-Compatible RP-UHPLC Analysis of Tricarboxylic Acid Cycle and Related Metabolites in Biological Fluids: Application to Human Urine.

I. Wilson, P. Rainville, Kerri M. Smith, 2020, Analytical chemistry.

Drug development assay approaches, including molecular imprinting and biomarkers

I. Wilson, H. Hill, E. Reid, 1998 .

Flow injection spectroscopic analysis of model drugs using on-line UV-diode array, FT-infrared and 1H-nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry.

I. Wilson, E. Lenz, A. Sage, 2000, The Analyst.

Chromatography and Isolation of Insect Hormones and Pheromones

I. Wilson, Related Compounds, A. McCaffery, 1990, Chromatographic Society Symposium Series.

Ethyl sulphate, a chemically reactive human metabolite of ethanol?

I. Wilson, R. Waring, S. Mitchell, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

A 1H NMR spectroscopic study of the biochemical effects of ifosfamide in the rat: evaluation of potential biomarkers

I. Wilson, J. Nicholson, E. Lenz, 2000 .

High Resolution 1H NMR Spectroscopic Monitoring of Extraction of Model Glucuronides on Phenylboronic Acid and C18 Bonded Phases

I. Wilson, J. Nicholson, M. Tugnait, 1994 .

Proton Nuclear Magnetic Spectroscopy: A Novel Method for the Study of Solid Phase Extraction

I. Wilson, J. Nicholson, 1994 .

Derivatized β-cyclodextrins combined with high field NMR for enantiomer analysis: application to ICI 185,282 5(Z)-7-([2RS,4RS,5SR]-4-

I. Wilson, David A R Williams, A. Taylor, 1991 .

Use of high-field nuclear magnetic resonance spectroscopy for the analysis of biological fluids

I. Wilson, J. Nicholson, F. Y. Ghauri, 1991 .

Revised method of proton NMR urinalysis for detecting inborn errors of metabolism: a critique.

I. Wilson, J. Nicholson, 1988, Clinical chemistry.

An unexpected selectivity of a propranolol-derived molecular imprint for tamoxifen.

I. Wilson, P. Martin, G. Jones, 2001, The Analyst.

Photo-isomerization of azadirachtin studied by high performance liquid chromatography coupled to high field proton NMR spectroscopy

E. Morgan, I. Wilson, M. Hofmann, 1994 .

A method for the direct injection and analysis of small volume human blood spots and plasma extracts containing high concentrations of organic solvents using revered-phase 2D UPLC/MS.

I. Wilson, R. Plumb, P. Rainville, 2015, The Analyst.

Prostatic tissue protein alterations due to delayed time to freezing

I. Wilson, David H Jackson, R. Tonge, 2006, Proteomics.

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

Joshua D. Knowles, D. Kell, R. Goodacre, 2011, Nature Protocols.

Analysis of Rat Urine Using Rapid Microbore Metabolic Profiling ( RAMMP ) HILIC Chromatography with Ion Mobility-MS

I. Wilson, R. Plumb, P. Rainville, 2018 .

Metabolic Profiling Approaches for Biomarkers of Ethanol Intake

I. Wilson, H. Gika, 2016 .

Global metabolic profiling (metabonomics/metabolomics) using dried blood spots: advantages and pitfalls.

I. Wilson, 2011, Bioanalysis.

Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile.

I. Wilson, R. Plumb, P. Rainville, 2009, Journal of proteome research.

19F NMR Spectroscopy: Applications in Pharmaceutical Studies

I. Wilson, J. Lindon, 2015 .

Selectivity in the high-performance liquid chromatography of ecdysteroids

E. Morgan, I. Wilson, I. Wilson, 1994 .

Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice

Alison J. Foster, I. Wilson, J. G. Kenna, 2016, Archives of Toxicology.

Thermal Gradients for the Control of Elution in RP-LC: Application to the Separation of Model Drugs

I. Wilson, A. Edge, S. Shillingford, 2007 .

Superheated water chromatography-nuclear magnetic resonance spectroscopy of kava lactones.

I. Wilson, E. Lenz, Roger M. Smith, 2005, Phytochemical analysis : PCA.

A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat.

P. Haycock, I. Wilson, J. Lindon, 2002, Journal of pharmaceutical and biomedical analysis.

An investigation of the properties of a "shielded" phase for the solid phase extraction of acidic and basic compounds.

E. Morgan, I. Wilson, P. Martin, 1996, Journal of pharmaceutical and biomedical analysis.

Solid state NMR and extraction studies on "phenyl"-bonded stationary phases used for solid phase extraction.

E. Morgan, I. Wilson, K. Albert, 1995, Journal of pharmaceutical and biomedical analysis.

Gut microbiome interactions with drug metabolism, efficacy, and toxicity.

Jeremy K Nicholson, Ian D Wilson, I. Wilson, 2017, Translational research : the journal of laboratory and clinical medicine.

Gut microbiota modulation of chemotherapy efficacy and toxicity

Ian D. Wilson, Jeremy K. Nicholson, Julian Teare, 2017, Nature Reviews Gastroenterology &Hepatology.

Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides.

Caroline H. Johnson, I. Wilson, J. Lindon, 2011, Organic & biomolecular chemistry.

The comparative metabonomics of age-related changes in the urinary composition of male Wistar-derived and Zucker (fa/fa) obese rats.

M. Rantalainen, I. Wilson, E. Lenz, 2006, Molecular bioSystems.

NMR and QSAR studies on the transacylation reactivity of model 1β-O-acyl glucuronides. I: design, synthesis and degradation rate measurement

I. Wilson, J. Lindon, J. Nicholson, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

An NMR study of the metabolic fate of 2-, 3- and 4-fluorobenzyl alcohols in the rat: detection of N-acetylcysteinyl conjugates as minor metabolites in urine.

I. Wilson, J. Nicholson, I D Wilson, 2003, Journal of pharmaceutical and biomedical analysis.

Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat

I. Wilson, J. Lindon, J. Nicholson, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Application of microbore HPLC in combination with tandem MS for the quantification of rosuvastatin in human plasma.

I. Wilson, Tim P Sangster, K. A. Oudhoff, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Determination of two COX-2 inhibitors in serum and synovial fluid of patients with inflammatory arthritis by ultra performance liquid chromatography-inductively coupled plasma mass spectroscopy and quadrupole time-of-flight mass spectrometry.

I. Wilson, G. Theodoridis, H. Gika, 2009, Journal of pharmaceutical and biomedical analysis.

Quantitative structure chromatography relationships in reversed-phase high performance liquid chromatography: Prediction of retention behaviour using theoretically derived molecular properties

R. Glen, C. Beddell, I. Wilson, 1993 .

Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats.

I. Wilson, J. Nicholson, J. Sidaway, 2011, Journal of proteome research.

Gut microbiome modulates the toxicity of hydrazine: a metabonomic study.

Elaine Holmes, Ian D Wilson, Glenn Gibson, 2009, Molecular bioSystems.

Sensitive sulphur-specific detection of omeprazole metabolites in rat urine by high-performance liquid chromatography/inductively coupled plasma mass spectrometry.

I. Wilson, B. Jensen, Christopher J. Smith, 2004, Rapid communications in mass spectrometry : RCM.

High-performance liquid chromatography coupled to high-field proton nuclear magnetic resonance spectroscopy: application to the urinary metabolites of ibuprofen.

I. Wilson, M. Hofmann, M. Spraul, 1993, Analytical chemistry.

Investigation of the metabolic fate of 2-, 3- and 4-bromobenzoic acids in bile-duct-cannulated rats by inductively coupled plasma mass spectrometry and high-performance liquid chromatography/inductively coupled plasma mass spectrometry/electrospray mass spectrometry.

I. Wilson, J. Nicholson, B. Jensen, 2005, Rapid communications in mass spectrometry : RCM.

Use of cyclodextrins and their derivatives for chiral analysis by high field nuclear magnetic resonance spectroscopy

I. Wilson, J. Nicholson, David A R Williams, 1992 .

Global metabolic profiling procedures for urine using UPLC–MS

E. Want, I. Wilson, J. Nicholson, 2010, Nature Protocols.

A Note on Overpressure Thin-Layer Chromatography of Ecdysteroids

I. Wilson, R. Lafont, H. Read, 1990 .

Electroosmotically driven thin-layer electrochromatography on silica media

I. Wilson, T. Shafik, A. Howard, 1999 .

Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry

John C Lindon, Ian D Wilson, Toby J Athersuch, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Planar chromatography coupled with spectroscopic techniques

I. Wilson, G. Somsen, W. Morden, 1995 .

Chromatographic procedures for phytoecdysteroids

E. Morgan, I. Wilson, I. Wilson, 1994 .

Thin-Layer Chromatography of Ecdysteroids: Detection and Identification

I. Wilson, R. Lafont, C. J. Porter, 1990 .

Advances in Instrumentalized TLC

I. Wilson, 1988 .

THIN-LAYER CHROMATOGRAPHY AND HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY OF [3H]METABOLITES OF 20-HYDROXYECDYSONE

I. Wilson, R. Lafont, 1986 .

Thin-layer chromatography of ecdysteroids

I. Wilson, 1985 .

The state of the art in thin-layer chromatography-mass spectrometry: a critical appraisal.

I. Wilson, 1999, Journal of chromatography. A.

HPLC-MS/MS methods for the quantitative analysis of ophthalmic acid in rodent plasma and hepatic cell line culture medium.

K. Kolaja, H. Westerhoff, S. Geenen, 2011, Journal of pharmaceutical and biomedical analysis.

Comparison of the properties of polymeric and C8 based materials for solid phase extraction.

I. Wilson, P. Martin, 1998, Journal of pharmaceutical and biomedical analysis.

Evaporation-induced solvent migration in electrically-driven thin layer chromatography

I. Wilson, T. Shafik, A. Howard, 1999 .

8.05 – Insect Hormones and Insect Chemical Ecology

E. Morgan, I. Wilson, I. Wilson, 1999 .

Chapter 10 Biomedical applications of directly–coupled chromatography—nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS)

I. Wilson, J. Lindon, J. Nicholson, 2003 .

Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites.

I. Wilson, M. Hofmann, M. Spraul, 1993, Journal of pharmaceutical and biomedical analysis.

Current practice of liquid chromatography-mass spectrometry in metabolomics and metabonomics.

Robert S Plumb, Ian D Wilson, I. Wilson, 2014, Journal of pharmaceutical and biomedical analysis.

High-performance liquid chromatography coupled to nuclear magnetic resonance spectroscopy: Application to the ecdysteroids of Silene otites

E. Morgan, I. Wilson, B. Wright, 1998 .

Selective effects of mobile and stationary phases in reversed-phase high-performance liquid chromatography of ecdysteroids

E. Morgan, I. Wilson, C. R. Bielby, 1982 .

Normal-phase thin-layer chromatography on silica gel with simultaneous paraffin impregnation for subsequent reversed-phase thin-layer chromatography in a second dimension

I. Wilson, 1984 .

19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid].

I. Wilson, J. Nicholson, J. Troke, 1990, Journal of pharmaceutical and biomedical analysis.

Drug Determination in Therapeutic and Forensic Contexts

I. Wilson, E. Reid, 2012, Methodological Surveys in Biochemistry and Analysis.

The use of graphitized carbon black in solid phase extraction: comparison with C18 bonded silica gel.

I. Wilson, D. Roberts, R. Ruane, 1989, Journal of pharmaceutical and biomedical analysis.

Recent Advances in Chiral Separations

I. Wilson, D. Stevenson, Recent Advances, 1991, Chromatographic Society Symposium Series.

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts

I. Wilson, J. Nicholson, E. Holmes, 2019, Analytical chemistry.

Picolinic acid: a mobile phase additive for improved chromatography of metal-chelating heterocyclic acids and β-diketones

I. Wilson, D. Roberts, R. Ruane, 1989 .

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.

David Broadhurst, Warwick B Dunn, Ian D Wilson, 2012, Bioanalysis.

Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis.

John C Lindon, Ian D Wilson, I. Wilson, 2006, Journal of medicinal chemistry.

Biomedical and Pharmaceutical Applications of HPLC–NMR and HPLC–NMR–MS

I. Wilson, J. Lindon, J. Nicholson, 2003 .

Supercritical fluid chromatography and extraction of pharmaceuticals

I. Wilson, R. Ruane, P. Davis, 1993 .

Global metabolic profiling of animal and human tissues via UPLC-MS

Robert S Plumb, Elaine Holmes, Jeremy K Nicholson, 2012, Nature Protocols.

Determination of penicillamine and other thiols by combined high-performance liquid chromatography and post-column reaction with Ellman's reagent: application to human urine.

I. Wilson, A. Mclean, D. Beales, 1981, Journal of chromatography.

Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation.

Elaine Holmes, John C Lindon, Jeremy K Nicholson, 2008, Analytical chemistry.

Identification of the Thiophene Ring of Methapyrilene as a Novel Bioactivation-Dependent Hepatic Toxicophore

Ian D. Wilson, John R. Harding, Dominic P. Williams, 2008, Journal of Pharmacology and Experimental Therapeutics.

Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat.

Elaine Holmes, Robert Tonge, Janice Nickson, 2006, Journal of proteome research.

Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration.

I. Wilson, J. Nicholson, J. Castro-Pérez, 2003, Rapid communications in mass spectrometry : RCM.

Advances in Ecdysteroid High Performance Liquid Chromatography

I. Wilson, R. Lafont, 1990 .

Variations in ecdysteroid levels in 5th instar larvae of Schistocerca gregaria in gregarious and solitary phases

E. Morgan, I. Wilson, 1978 .

Sample preparation for the chromatographic determination of ecdysteroids using solid-phase extraction methods.

E. Morgan, I. Wilson, S. J. Murphy, 1990 .

Comparison of high-performance liquid chromatography and gas chromatography for the analysis of ecdysteroids.

E. Morgan, I. Wilson, A. Mclean, 1980, Journal of chromatography.

The metabolic fate of fenclozic acid in chimeric mice with a humanized liver

R. A. Thompson, I. Wilson, Y. Morikawa, 2018, Archives of Toxicology.

Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

I. Wilson, S. Sarda, H. Jones, 2016, Archives of Toxicology.

The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse

I. Wilson, S. Sarda, H. Jones, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid

I. Wilson, J. G. Kenna, S. Stahl, 2013, Archives of Toxicology.

Recent Advances in Thin-Layer Chromatography

I. Wilson, R. Ruane, F. Dallas, 1988, Springer US.

Ion-pair reversed-phase thin-layer chromatography of organic acids : Re-investigation of the effects of solvent pH on RF values

I. Wilson, 1986 .

Factors affecting the ion-pair reversed-phase thin-layer chromatogrphy of organic acids on paraffin-coated and C18 bonded silica gel

I. Wilson, S. Lewis, 1984 .

Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS

I. Wilson, J. Nicholson, J. Castro-Pérez, 2003, Xenobiotica; the fate of foreign compounds in biological systems.

Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.

Caroline H. Johnson, I. Wilson, J. Lindon, 2009, Organic & biomolecular chemistry.

Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein

I. Wilson, J. Errey, B. G. Davis, 2014 .

Integrated HPLC-MS and 1H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides

I. Wilson, J. Lindon, J. Nicholson, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Nuclear magnetic resonance (NMR) and quantitative structure–activity relationship (QSAR) studies on the transacylation reactivity of model 1β-O-acyl glucuronides. II: QSAR modelling of the reaction using both computational and experimental NMR parameters

J C Lindon, I. Wilson, J. Lindon, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism

I. Wilson, J. Lindon, J. Nicholson, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC-NMR: Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid.

I. Wilson, S. Hansen, J. Lindon, 1996, Analytical chemistry.

750 MHz HPLC-NMR spectroscopic studies on the separation and characterization of the positional isomers of the glucuronides of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid.

I. Wilson, M. Hofmann, M. Spraul, 1996, Analytical chemistry.

Identification of a novel human circulating metabolite of tenofovir disoproxil fumarate with LC-MS/MS.

I. Wilson, E. Holmes, R. Plumb, 2015, Bioanalysis.

A comparison of radio-thin-layer and radio-high-performance liquid chromatography for ecdysteroid metabolism studies

E. Morgan, I. Wilson, C. Blais, 1988 .

Solid-Phase Extraction Mediated by Covalent Bonding: APPLICATIONS OF IMMOBILIZED PHENYLBORONIC ACID

I. Wilson, P. Martin, 2000 .

Immobilized phenylboronic acids for the selective extraction of beta-blocking drugs from aqueous solution and plasma.

I. Wilson, P. Martin, B. Leadbetter, 1993, Journal of pharmaceutical and biomedical analysis.

Examination of Conditions in Supercritical Fluid Chromatography for Analysis of Ecdysteroids

E. Morgan, I. Wilson, Huiping Huang, 1990 .

Gas chromatography of ecdysteroids as their trimethylsilyl ethers

E. Morgan, I. Wilson, C. R. Bielby, 1986 .

Managing the challenge of chemically reactive metabolites in drug development

Ian D. Wilson, Alan Boobis, Chris E. P. Goldring, 2011, Nature Reviews Drug Discovery.

Acyl glucuronide reactivity in perspective.

I. Wilson, T. Athersuch, A. Stachulski, 2020, Drug discovery today.

Evaluation of liquid chromatography coupled with high‐field 1H NMR spectroscopy for drug metabolite detection and characterization: The identification of paracetamol metabolites in urine and bile

I. Wilson, M. Hofmann, J. Nicholson, 1994, NMR in biomedicine.

The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice

R. Wehr, I. Wilson, I. Wilson, 2018, Archives of Toxicology.

The pharmacokinetics and metabolism of lumiracoxib in chimeric humanized and murinized FRG mice

R. Wehr, I. Wilson, I. Wilson, 2017, Biochemical pharmacology.

Genetically Humanized Animal Models

I. Wilson, C. Wolf, N. Scheer, 2017 .

A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity.

I. Wilson, N. Scheer, 2016, Drug discovery today.

Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone

I. Wilson, K. Spagou, A. Barnes, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice

I. Wilson, S. Sarda, J. Foster, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Drug-drug interactions and metabolism in cytochrome P450 2C knockout mice: application to troleandomycin and midazolam.

I. Wilson, M. Hutchison, R. Gallagher, 2013, Biochemical pharmacology.

Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers

I. Wilson, J. G. Kenna, Y. Morikawa, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium.

K. Kolaja, H. Westerhoff, S. Geenen, 2011, Journal of pharmaceutical and biomedical analysis.

Age and Microenvironment Outweigh Genetic Influence on the Zucker Rat Microbiome

I. Wilson, J. Nicholson, E. Holmes, 2014, PloS one.

Application of 1H NMR spectroscopy to the metabolic phenotyping of rodent brain extracts: A metabonomic study of gut microbial influence on host brain metabolism

I. Wilson, J. Nicholson, J. Sidaway, 2017, Journal of pharmaceutical and biomedical analysis.

Global metabolite profiling of human colorectal cancer xenografts in mice using HPLC-MS/MS.

I. Wilson, R. Odedra, R. Wilkinson, 2013, Journal of proteome research.

The New Data Quality Task Group (DQTG): ensuring high quality data today and in the future

M. Viant, C. Guillou, W. Dunn, 2014, Metabolomics.

Methodological considerations in the development of HPLC-MS methods for the analysis of rodent plasma for metabonomic studies.

I. Wilson, R. Bonner, R. Odedra, 2009, Molecular bioSystems.

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies

Ian D. Wilson, Royston Goodacre, David Broadhurst, 2018, Metabolomics : Official journal of the Metabolomic Society.

LC-MS-based holistic metabolic profiling. Problems, limitations, advantages, and future perspectives.

Ian D Wilson, I. Wilson, G. Theodoridis, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The Development of Metabolic Phenotyping—A Historical Perspective

I. Wilson, J. Lindon, 2016 .

Seasonal production of moulting hormone in the barnacle Semibalanus balanoides

E. Morgan, I. Wilson, C. R. Bielby, 2005 .

Hydrogen/deuterium exchange using a coaxial sheath-flow interface for capillary electrophoresis/mass spectrometry.

I. Wilson, L. Tetler, M. Palmer, 2000, Rapid communications in mass spectrometry : RCM.

HPLC-MS-based methods for the study of metabonomics.

Ian D Wilson, I. Wilson, H. Major, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Site and Strain-Specific Variation in Gut Microbiota Profiles and Metabolism in Experimental Mice

I. Wilson, B. Telfer, I. Stratford, 2010, PloS one.

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

E. Want, I. Wilson, J. Nicholson, 2010, Proceedings of the National Academy of Sciences.

Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

Jeremiah Stamler, Elaine Holmes, John C Lindon, 2007, Analytical chemistry.

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer

L. Maitre, I. Wilson, M. Coen, 2016, Archives of Toxicology.

D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach.

I. Wilson, E. Lock, E. Lenz, 2005, Toxicology.

Profiling biological samples using ultra performance liquid chromatography-inductively coupled plasma-mass spectrometry (UPLC-ICP-MS) for the determination of phosphorus and sulfur-containing metabolites.

I. Wilson, R. Wilkinson, C. Duckett, 2011, Molecular bioSystems.

An Overview of Metabolic Phenotyping and Its Role in Systems Biology

I. Wilson, J. Lindon, E. Holmes, 2019, The Handbook of Metabolic Phenotyping.

The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin.

I. Wilson, J. Sidaway, R. Plumb, 2007, Journal of pharmaceutical and biomedical analysis.

Isotopic enrichment enhancement in metabonomic analysis of UPLC-MS data sets

I. Wilson, J. Nicholson, T. Athersuch, 2007 .

A metabonomic analysis of plasma from Zucker rat strains using gas chromatography/mass spectrometry and pattern recognition.

Ian D Wilson, I. Wilson, R. Williams, 2006, Rapid communications in mass spectrometry : RCM.

A multi-analytical platform approach to the metabonomic analysis of plasma from normal and Zucker (fa/fa) obese rats.

I. Wilson, A. J. Wilson, R. Plumb, 2006, Molecular bioSystems.

Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat

F. Westwood, I. Wilson, E. Lenz, 2005, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

A metabonomic analysis of insect development: 1H-NMR spectroscopic characterization of changes in the composition of the haemolymph of larvae and pupae of the tobacco hornworm, Manduca sexta

I. Wilson, S. Reynolds, J. Lindon, 2008 .

Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC–MS and ion mobility enabled HILIC–MS

I. Wilson, M. Coen, R. Plumb, 2019, Metabolomics.

Detection and identification of morphine in urine extracts using thin-layer chromatography and tandem mass spectrometry.

I. Wilson, I. Watson, W. Morden, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Quantification of endogenous aminoacids and aminoacid derivatives in urine by hydrophilic interaction liquid chromatography tandem mass spectrometry.

I. Wilson, G. Theodoridis, H. Gika, 2021, Journal of chromatography. A.

Hyphenation and hypernation the practice and prospects of multiple hyphenation.

I. Wilson, U. Brinkman, I D Wilson, 2003, Journal of chromatography. A.

Use of Cyclic Ion Mobility Spectrometry (cIM)-Mass Spectrometry to Study the Intramolecular Transacylation of Diclofenac Acyl Glucuronide.

I. Wilson, J. Vissers, R. Plumb, 2021, Analytical chemistry.

NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases.

I. Wilson, J. Nicholson, M. Tugnait, 1991, Journal of pharmaceutical and biomedical analysis.

Detection of metabolic alterations in non-tumor gastrointestinal tissue of the Apc(Min/+) mouse by (1)H MAS NMR spectroscopy.

Hector C. Keun, Ian D. Wilson, Friederike Teichert, 2009, Journal of proteome research.

A GC-MS metabolic profiling study of plasma samples from mice on low- and high-fat diets.

I. Wilson, M. Klapa, G. Theodoridis, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Towards quality assurance and quality control in untargeted metabolomics studies

Krista A. Zanetti, Christina M. Jones, L. Derr, 2019, Metabolomics.

A Note on Selective Separation of 20,22-Dihydroxyecdysteroids from Insect and Plant Material with Immobilized Phenylboronic Acid

E. Morgan, I. Wilson, S. J. Murphy, 1990 .

Bioanalysis of p-trifluoromethylmandelic acid and Mosher's acid by chiral gas chromatography and fluorine nuclear magnetic resonance to study chiral inversion: application to rat urine samples.

I. Wilson, D. Stevenson, D. Matthews, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Application of High Temperature LC to the Separation of AZD5438 (4-(1-Isopropyl-2-methyl-1H-imidazol-5-yl)-N-[4-(methylsulfonyl)phenyl]pyrimidin-2-amine) and Its Metabolites: Comparison of LC, UPLC and HTLC

I. Wilson, Christopher J. Smith, R. Payne, 2009 .

Quantification of the In Vitro and In Vivo Metabolic Fates of 2-, 3- and 4-Bromobenzoic Acids Using High Temperature LC Coupled to ICP-MS and Linear Ion Trap MS

I. Wilson, Christopher J. Smith, Christopher J Bailey, 2008 .

Investigation of a range of stationary phases for the separation of model drugs by HPLC using superheated water as the mobile phase

I. Wilson, 2000 .

Temperature as a variable in liquid chromatography: development and application of a model for the separation of model drugs using water as the eluent.

I. Wilson, R. Payne, A. Edge, 2006, Journal of chromatography. A.

IMMOBILIZED BORONIC ACIDS: EXTRACTION

I. Wilson, P. Martin, 2000 .

An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma.

James P. Murphy, I. Wilson, J. Nicholson, 2015, The Analyst.

Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies.

R. Glen, C. Beddell, I. Wilson, 1992, Biochemical pharmacology.

Protocol for quality control in metabolic profiling of biological fluids by U(H)PLC-MS.

Ian D Wilson, Georgios Theodoridis, I. Wilson, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Advances in liquid chromatography coupled to mass spectrometry for metabolic phenotyping

Ian D. Wilson, Georgios Theodoridis, I. Wilson, 2014 .

A targeted ultra performance liquid chromatography - Tandem mass spectrometric assay for tyrosine and metabolites in urine and plasma: Application to the effects of antibiotics on mice.

I. Wilson, J. Nicholson, M. Dumas, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Drugs, bugs, and personalized medicine: Pharmacometabonomics enters the ring

Ian D Wilson, I. Wilson, 2009, Proceedings of the National Academy of Sciences.

Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics.

I. Wilson, H. Major, E. Lenz, 2004, Journal of pharmaceutical and biomedical analysis.

A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity.

I. Wilson, H. Major, E. Lenz, 2004, The Analyst.

Evaluation of the use of UPLC-TOFMS with simultaneous [14C]-radioflow detection for drug metabolite profiling: application to propranolol metabolites in rat urine.

I. Wilson, T. Athersuch, R. Sison, 2008, Journal of pharmaceutical and biomedical analysis.

Effect of carbon loading on the extraction properties of C-18 bonded silica used for solid-phase extraction of acidic and basic analytes.

E. Morgan, I. Wilson, P. Martin, 1997, Analytical chemistry.

Evaluation of a Molecular-imprinted Polymer for use in the Solid Phase Extraction of Propranolol From Biological Fluids

Ian D. Wilson, Paul D. Martin, Kenneth Jones, 1997 .

The metabonomics of aging and development in the rat: an investigation into the effect of age on the profile of endogenous metabolites in the urine of male rats using 1H NMR and HPLC-TOF MS.

M. Rantalainen, I. Wilson, E. Lenz, 2005, Molecular bioSystems.

Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships.

C. Beddell, I. Wilson, J. Lindon, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

LC‐MS‐Based Nontargeted Metabolomics

I. Wilson, G. Theodoridis, H. Gika, 2013 .

Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays).

I. Wilson, J. Nicholson, E. Holmes, 2011, Phytochemical analysis : PCA.

Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis.

Cheng Ji, Neil Kaplowitz, Georgios Theodoridis, 2011, Journal of proteome research.

Metabolic profiling of human urine by CE-MS using a positively charged capillary coating and comparison with UPLC-MS.

E. Nevedomskaya, I. Wilson, G. Theodoridis, 2011, Molecular bioSystems.

Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies.

Ian D Wilson, Nikolaos Raikos, Georgios Theodoridis, 2010, Journal of separation science.

Hyphenated techniques for global metabolite profiling.

I. Wilson, G. Theodoridis, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Topics in Xenobiochemistry: Do metabolic pathways exist for xenobiotics? The micro-metabolism hypothesis

I. Wilson, J. Nicholson, I D Wilson, 2003, Xenobiotica; the fate of foreign compounds in biological systems.

Directly coupled high-performance liquid chromatography and nuclear magnetic resonance spectroscopic with chemometric studies on metabolic variation in Sprague--Dawley rats.

E Holmes, I. Wilson, J. Nicholson, 2001, Analytical biochemistry.

The Role of Mass Spectrometry in Nontargeted Metabolomics

Ian D. Wilson, Helen G. Gika, Georgios Theodoridis, 2014 .

Untargeted LC/MS-based metabolic phenotyping (metabonomics/metabolomics): The state of the art.

Robert S Plumb, Ian D Wilson, Georgios Theodoridis, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Qualitative and Quantitative Characterization of the Metabolome, Lipidome and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC-MS

S. Geenen, I. Wilson, J. Vissers, 2013 .

Hydrophilic interaction chromatography-mass spectrometry for anionic metabolic profiling of urine from antibiotic-treated rats.

I. Wilson, J. Swann, G. D. de Jong, 2014, Journal of pharmaceutical and biomedical analysis.

Application of a Novel Mass Spectral Data Acquisition Approach to Lipidomic Analysis of Liver Extracts from Sitaxentan-treated Liver-Humanized PXB Mice.

Ian D. Wilson, Lee A. Gethings, I. Wilson, 2019, Journal of proteome research.

Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism

I. Wilson, D. Weston, G. V. Van Berkel, 2011, Xenobiotica; the fate of foreign compounds in biological systems.

Integration of microfluidic LC with HRMS for the analysis of analytes in biofluids: past, present and future.

I. Wilson, J. Langridge, M. Wrona, 2015, Bioanalysis.

Characterisation of C18-bonded silicas for solid-phase extraction by solid-state NMR spectroscopy

I. Wilson, K. Albert, R. Brindle, 1994 .

Fluorescence detection in packed-column supercritical fluid chromatographic separations

I. Wilson, Roger M. Smith, O. Chienthavorn, 1998 .

Investigation of water environments in a C18 bonded silica phase using 1H magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy.

I. Wilson, J. Lindon, J. Nicholson, 2001, The Analyst.

An investigation of the effects of carbon loading and endcapping on the solid-phase extraction of beta-blockers onto C18 bonded silica gel.

I. Wilson, A. Fairbrother, P. Martin, 1993, Journal of pharmaceutical and biomedical analysis.

The use of C18 bonded silica in the solid phase extraction of basic drugs - possible role for ionic interactions with residual silanols.

I. Wilson, R. Ruane, 1987, Journal of pharmaceutical and biomedical analysis.

TLC combined with tandem mass spectrometry : application to the analysis of antipyrine and its metabolites in extracts of human urine

I. Wilson, P. Martin, W. Morden, 1992 .

BIOACTIVE ANALYTES, Including CNS Drugs, Peptides, and Enantiomers

I. Wilson, E. Reid, B. Scales, 2013, Methodological Surveys in Biochemistry and Analysis.

Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine.

I. Wilson, J. Lindon, J. Nicholson, 2002, Rapid communications in mass spectrometry : RCM.

High-performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine-specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2-fluoro-4-iodoaniline.

I. Wilson, J. Lindon, J. Nicholson, 2003, Rapid Communications in Mass Spectrometry.

The metabolism of [14C]N-ethoxycarbonyl-3-morpholinosydnonimine (molsidomine) in man.

I. Wilson, H. Illing, I D Wilson, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of 4-bromoaniline in the bile-cannulated rat: application of ICPMS (79/81Br), HPLC-ICPMS & HPLC-oaTOFMS

I. Wilson, C. Duckett, M. McCullagh, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolism of 2-fluoro-4-iodoaniline in earthworm Eisenia veneta using 19F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS (127I)

I. Wilson, J. Lindon, J. Nicholson, 2007, Xenobiotica; the fate of foreign compounds in biological systems.

Analysis of a [14C]-labelled platinum anticancer compound in dosing formulations and urine using a combination of HPLC-ICPMS and flow scintillation counting

I. Wilson, D. Roberts, F. Abou-Shakra, 2002 .

Problems and solutions in chiral thin-layer chromatography: a two-phase “Pirkle” modified amino-bonded plate

I. Wilson, T. Spurway, R. Ruane, 1991 .

A novel LC-MS approach for the detection of metabolites in DMPK studies.

I. Wilson, J. Nicholson, R. Plumb, 2010, Bioanalysis.

Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena.

I. Wilson, J. Nicholson, E. Holmes, 2019, Journal of proteome research.

Anionic metabolic profiling of urine from antibiotic-treated rats by capillary electrophoresis–mass spectrometry

G. J. Jong, I. Wilson, J. Swann, 2013, Analytical and Bioanalytical Chemistry.

Metabonomic and microbiological analysis of the dynamic effect of vancomycin-induced gut microbiota modification in the mouse.

Elaine Holmes, Jeremy K Nicholson, Ian D Wilson, 2008, Journal of proteome research.

An overview of fecal sample preparation for global metabolic profiling.

Ian D Wilson, Olga Deda, I. Wilson, 2015, Journal of pharmaceutical and biomedical analysis.

UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction.

Georgios Theodoridis, I. Wilson, G. Theodoridis, 2009, Journal of proteome research.

Application of 1 H- and 19 F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat

I. Wilson, J. Nicholson, J. A. Evans, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Molecular imprints as sorbents for solid phase extraction: potential and applications

Ian D. Wilson, Paul D. Martin, I. Wilson, 1998 .

Application of a hybrid zwitterionic hydrophilic interaction liquid chromatography column in metabolic profiling studies.

I. Wilson, G. Theodoridis, H. Gika, 2022, Journal of chromatography. A.

A perspective on the standards describing mass spectrometry-based metabolic phenotyping (metabolomics/metabonomics) studies in publications.

I. Wilson, G. Theodoridis, C. Virgiliou, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Global metabolic profiling for the study of alcohol-related disorders.

Ian D Wilson, I. Wilson, H. Gika, 2014, Bioanalysis.

Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine.

Ian D Wilson, I. Wilson, G. Theodoridis, 2008, Journal of separation science.

Top-down systems biology modeling of host metabotype-microbiome associations in obese rodents.

M. Rantalainen, I. Wilson, J. Nicholson, 2009, Journal of proteome research.

The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: Application to the metabolism of diclofenac

I. Wilson, S. Sarda, E. Karlsson, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolite Detection and Profiling

Ian D. Wilson, I. Wilson, 2014 .

HPLC–MS Profiling and Structural Identification of [14C]-Diclofenac Metabolites in Mouse Bile

I. Wilson, S. Sarda, K. Pickup, 2014, Chromatographia.

Directly coupled HPLC-NMR and its application to drug metabolism.

I. Wilson, J. Lindon, J. Nicholson, 1997, Drug metabolism reviews.

Enhanced performance in the determination of ibuprofen 1-β-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid chromatography-time-of-flight mass spectrometry.

C. Creaser, I. Wilson, D. Weston, 2013, Journal of chromatography. A.

An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry.

Ian D Wilson, Daniel J Weston, C. Creaser, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Liquid chromatography coupled with high-field proton nuclear magnetic resonance spectroscopy : current status and future prospects

I. Wilson, M. Hofmann, M. Spraul, 1993 .

SARS-CoV-2 Infection Biomarkers Reveal an Extended RSAD2 Dependant Metabolic Pathway

G. Evans, S. Almo, I. Wilson, 2023, medRxiv.

Generation of ultrahigh peak capacity LC separations via elevated temperatures and high linear mobile-phase velocities.

Robert S Plumb, Jeremy K Nicholson, Ian D Wilson, 2006, Analytical chemistry.

Rapid multi-component detection of fluorinated drug metabolites in whole urine from a ‘cassette’ dose study using high resolution 19F NMR spectroscopy

I. Wilson, J. Nicholson, O. Corcoran, 1999 .

Metabolomics: An Analytical Perspective

I. Wilson, G. Theodoridis, H. Gika, 2013 .

Hypernation: Liquid chromatography combined with multiple spectroscopies

I. Wilson, 2002 .

Molecular phenotyping of a UK population: defining the human serum metabolome

Joshua D. Knowles, D. Kell, R. Goodacre, 2014, Metabolomics.

The chromatographic properties of a mixed-bed stationary phase combining reversed-phase and strong anion exchange properties

I. Wilson, R. Ruane, P. Davis, 1993 .

Packed-Column Supercritical Fluid Chromatography of γ-Blockers

I. Wilson, R. Ruane, C. Bailey, 1994 .

pH dependent formation of beta-glucuronidase resistant conjugates from the biosynthetic ester glucuronide of isoxepac.

I. Wilson, H. Illing, 1981, Biochemical pharmacology.

The development and application of coupled HPLC-NMR spectroscopy.

I. Wilson, J. Lindon, J. Nicholson, 1996, Advances in chromatography.

Erratum: Ethyl glucoside in human urine following dietry exposure: Detection by 1H NMR spectroscopy as a result of metabonomic screening of humans (Analyst (2004) 129 (259) DOI: 10.1039/b314316n)

P. Elliott, I. Wilson, J. Stamler, 2004 .

Methodology for assessing the properties of molecular imprinted polymers for solid phase extraction

I. Wilson, G. Jones, J. Olsen, 1999 .

Optimisation of procedures for the extraction of structural analogues of propranolol with molecular imprinted polymers for sample preparation.

I. Wilson, P. Martin, G. Jones, 2000, Journal of Chromatography A.

Use of an atmospheric solids analysis probe (ASAP) for high throughput screening of biological fluids: preliminary applications on urine and bile.

I. Wilson, J. Nicholson, R. Plumb, 2010, Journal of proteome research.

CHIRAL SEPARATIONS BY THIN-lAYER CHROMATOGRAPHY

I. Wilson, T. Spurway, R. Ruane, 1991 .

Prospects for Chiral Thin-Layer Chromatography

I. Wilson, R. Ruane, 1988 .

Direct coupling of chromatographic separations to NMR spectroscopy

I. Wilson, J. Lindon, J. Nicholson, 1996 .

Field-Flow Fractionation of Proteins.

I. Wilson, H. Cölfen, R. Hecker, 2000 .

Biofluid assay for peptide-related and other drugs

I. Wilson, H. Hill, E. Reid, 1996 .

Flow injection analysis with multiple on-line spectroscopic analysis (UV, IR, 1H-NMR and MS).

I. Wilson, E. Lenz, D. Louden, 2002, Journal of pharmaceutical and biomedical analysis.

Studies on the metabolism of 4-fluoroaniline and 4-fluoroacetanilide in rat: formation of 4-acetamidophenol (paracetamol) and its metabolites via defluorination and N-acetylation.

I. Wilson, J. Nicholson, G. Scarfe, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

Thin-layer chromatography: a neglected technique.

I. Wilson, 1996, Therapeutic drug monitoring.

Direct extraction of urinary analytes from undeveloped reversed-phase thin layer chromatography plates using a solvent gradient combined with on-line electrospray ionisation ion mobility-mass spectrometry.

C. Creaser, I. Wilson, D. Weston, 2012, The Analyst.

The metabolism and excretion of [14c] 2- and 4-chlorobenzoic acids in the rat.

I. Wilson, J. Nicholson, E. Partridge, 2000, Journal of pharmaceutical and biomedical analysis.

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

I. Wilson, F. Pognan, T. Orton, 2000, European journal of biochemistry.

Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development.

Yan Li, Hugues Dolgos, R. A. Thompson, 2011, Chemico-biological interactions.

The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.

I. Wilson, R. Jalan, M. Coen, 2020, Bioanalysis.

The analysis of acetaminophen ( paracetamol ) and 7 metabolites in rat , pig and human 1 plasma by U ( H ) PLC-MS 2

I. Wilson, R. Jalan, M. Coen, 2020 .

Hybrid organic/inorganic hybrid surface technology for increasing the performance of LC/MS(MS)-based drug metabolite identification studies: Application to gefitinib and metabolites in mouse plasma and urine.

I. Wilson, R. Plumb, L. Gethings, 2021, Journal of pharmaceutical and biomedical analysis.

A Novel Use of RIA and HPLC in the Identification of Plasma Metabolites of HR 158

I. Wilson, C. Bevan, J. D. Robinson, 1983 .

Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition.

I. Wilson, M. Spraul, J. Lindon, 1995, Journal of pharmaceutical and biomedical analysis.

Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry

I. Wilson, J. Lindon, J. Nicholson, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Enhanced Detection of Sulphur and Phospho-rous Containing Compounds in HPLC-Induc-tively Coupled Plasma Mass Spectrometry Using Chemical Resolution via Hexapole-Based Reaction with Oxygen

I. Wilson, F. Abou-Shakra, L. Weidolf, 2004 .

High-temperature ultra-performance liquid chromatography coupled to hybrid quadrupole time-of-flight mass spectrometry applied to ibuprofen metabolites in human urine.

I. Wilson, R. Plumb, J. Castro-Pérez, 2007, Rapid Communications in Mass Spectrometry.

Enhanced chromatographic efficiency obtained with vacuum jacketed columns facilitates the rapid UHPLC/MS/MS-based analysis of fasiglifam in rat plasma.

I. Wilson, R. Plumb, P. Rainville, 2022, Talanta.

Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration

I. Wilson, J. Nicholson, C. Duckett, 2007, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

I. Wilson, M. Hofmann, M. Spraul, 2002, Journal of pharmaceutical and biomedical analysis.

Investigation of the quantitative metabolic fate and urinary excretion of 3-methyl-4-trifluoromethylaniline and 3-methyl-4-trifluoromethylacetanilide in the rat.

I. Wilson, J. Lindon, J. Nicholson, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS.

J C Lindon, I. Wilson, J. Lindon, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat

I. Wilson, J. Nicholson, T. Athersuch, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy.

I. Wilson, M. Hofmann, M. Spraul, 2003, Journal of pharmaceutical and biomedical analysis.

Species differences in the metabolism of 14C-p-trifluoromethylaniline: production of an oxanilic acid as the major metabolite by the rat.

I. Wilson, J. Troke, J. Fromson, 1985, Biochemical pharmacology.

19F NMR Studies of the Metabolism of Trifluoromethylaniline

I. Wilson, J. Nicholson, J. Troke, 1988 .

Reactivity of thiols towards derivatives of 2- and 6-methyl-1,4-naphthoquinone bioreductive alkylating agents.

I. Wilson, A. Sartorelli, P. Wardman, 1987, Chemico-biological interactions.

Investigation of analytical variation in metabonomic analysis using liquid chromatography/mass spectrometry.

Lyle Burton, Ian D Wilson, Friederike Teichert, 2007, Rapid communications in mass spectrometry : RCM.

Comparison of non-hydrophobic C18 bonded thin-layer and high-performance thin-layer chromatography plates for reversed-phase thin-layer chromatography of ecdysteroids

I. Wilson, 1988 .

Ion-pair reversed-phase thin-layer chromatography of basic drugs using sulphonic acids.

I. Wilson, R. Ruane, 1988, Journal of chromatography.

UvA-DARE ( Digital Academic Repository ) Systems biology tools for toxicology

H. Westerhoff, J. Snoep, S. Geenen, 2017 .

The detection and characterization of analgesics and anti-inflammatory drugs on high performance thin-layer chromatography plates using tandem mass spectrometry: application to drugs and metabolites in urine.

I. Wilson, W. Morden, 1996, Rapid communications in mass spectrometry : RCM.

Systems biology tools for toxicology

H. Westerhoff, J. Snoep, S. Geenen, 2012, Archives of Toxicology.

Gut microbiome modulates the toxicity of hydrazine: a metabonomic study.

I. Wilson, J. Nicholson, J. Sidaway, 2009, Molecular bioSystems.

High temperature-ultra performance liquid chromatography-mass spectrometry for the metabonomic analysis of Zucker rat urine.

I. Wilson, G. Theodoridis, H. Gika, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Evaluation of the repeatability of ultra-performance liquid chromatography-TOF-MS for global metabolic profiling of human urine samples.

I. Wilson, G. Theodoridis, H. Gika, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A 1H NMR spectroscopic study of the biochemical effects of ifosfamide in the rat: evaluation of potential biomarkers

I. Wilson, J. Nicholson, E. Lenz, 2000, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Identification of the Thiophene Ring of Methapyrilene as a Novel Bioactivation-Dependent Hepatic Toxicophore

Dominic P. Williams, I. Wilson, J. Maggs, 2008, Journal of Pharmacology and Experimental Therapeutics.

Hypernation and Concatenation: Multiple On-Line Spectroscopic Analysis for Drug and Natural Product Characterisation

I. Wilson, 2008 .

A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity.

I. Wilson, N. Scheer, 2016, Drug discovery today.

I. Wilson, M. Mcphail, J. Nicholson, 2017, Analytical chemistry.

Towards quality assurance and quality control in untargeted metabolomics studies

Richard D. Beger, Mukesh Verma, Daniel Raftery, 2019, Metabolomics.

Molecular phenotyping of a UK population: defining the human serum metabolome

Douglas B. Kell, Joshua D. Knowles, Ian D. Wilson, 2014, Metabolomics.

Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions.

I. Wilson, J. Lindon, J. Nicholson, 2008, Analytical chemistry.

Phosphorus and sulfur metabonomic profiling of tissue and plasma obtained from tumour-bearing mice using ultra-performance liquid chromatography/inductively coupled plasma mass spectrometry.

I. Wilson, R. Wilkinson, C. Duckett, 2013, Rapid communications in mass spectrometry : RCM.

Mixture Analysis in Pharmaceutical R&D Using Hyphenated NMR Techniques

I. Wilson, J. Lindon, 2015 .

Ion Mobility-Enabled Metabolite Identification of Tienilic Acid and Tienilic Acid Isomer Using Mass-MetaSite and WebMetabase : Waters

I. Wilson, R. Plumb, G. Isaac, 2020 .

Contemporary developments in thin-layer chromatography.

I. Wilson, S. Lewis, 1985, Journal of pharmaceutical and biomedical analysis.

Comparison of non-hydrophobic C18 bonded and paraffin-coated silica gel reversed-phase thin-layer chromatography plates

I. Wilson, 1984 .

CHROMATOGRAPHY: THIN-LAYER (PLANAR) | Ion Pair Thin-Layer (Planar) Chromatography

I. Wilson, 2000 .

A Note on: A Preliminary Investigation of the Influence of the Stationary Phase in Ion-Pair Thin-Layer Chromatography

I. Wilson, R. Ruane, 1988 .

Contemporary Thin-Layer Chromatography: An Introduction

I. Wilson, 1988 .

Reversed-Phase TLC on Alkyl-Bonded and Paraffin-Coated Silica Gel

I. Wilson, 1984 .

Reversed phase ion-pair high performance thin layer chromatography of aromatic acids on cyanopropyl-bonded silica gel

I. Wilson, R. Ruane, G. Tomkinson, 1990 .

Normal and Reversed-Phase Ion-Pair Thin-Layer Chromatography with Bifunctional (Bolaform) Reagents

I. Wilson, R. Ruane, 1988 .

Reversed-phase ion-pair thin-layer chromatography of organic acids : Influence of ion-pair structure and solvent pH on RF

I. Wilson, J. Troke, 1986 .

An Early Description of Paper Chromatography?

E. Morgan, I. Wilson, E. D. Morgan, 2004 .

A QC approach to the determination of day-to-day reproducibility and robustness of LC-MS methods for global metabolite profiling in metabonomics/metabolomics.

I. Wilson, G. Theodoridis, H. Gika, 2012, Bioanalysis.

LC-MS-based holistic metabolic profiling. Problems, limitations, advantages, and future perspectives.

I. Wilson, G. Theodoridis, H. Gika, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.