A. Thorburn

发表

Autophagy and metastasis: another double-edged sword.

C. Kenific, A. Thorburn, J. Debnath, 2010, Current opinion in cell biology.

Regulation of the Pro-apoptotic Scaffolding Protein POSH by Akt*

A. Thorburn, T. Lyons, J. Thorburn, 2007, Journal of Biological Chemistry.

Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy.

A. Thorburn, M. McMahon, J. Thorburn, 1994, The Journal of biological chemistry.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

ZZ-dependent regulation of p62/SQSTM1 in autophagy

A. Thorburn, Y. Kwon, J. Moscat, 2018, Nature Communications.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Apoptosis and autophagy: regulatory connections between two supposedly different processes

A. Thorburn, Andrew Thorburn, 2007, Apoptosis.

Recruitment of TRADD, FADD, and caspase 8 to double-stranded RNA-triggered death inducing signaling complexes (dsRNA-DISCs)

A. Thorburn, M. Iordanov, B. Magun, 2005, Apoptosis.

The adaptor protein TRADD activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm

A. Thorburn, M. Morgan, L. Bender, 2005, Cell Death and Differentiation.

Death Domain Interactions in Death Receptor Signaling

A. Thorburn, M. Bender, 2005 .

Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms

P. Pandolfi, A. Thorburn, J. Thorburn, 2002, The Journal of cell biology.

Autophagy complexes cell death by necroptosis

A. Thorburn, S. Cramer, Megan L. Goodall, 2016, Oncotarget.

TRAIL Receptor Signaling Regulation of Chemosensitivity In Vivo but Not In Vitro

H. Ford, C. Korch, A. Thorburn, 2011, PloS one.

TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis.

A. Thorburn, H. Moses, P. Clark, 2010, The Journal of urology.

Tumor-derived Mutations in the TRAIL Receptor DR5 Inhibit TRAIL Signaling through the DR4 Receptor by Competing for Ligand Binding*

A. Thorburn, P. Clark, J. Thorburn, 2007, Journal of Biological Chemistry.

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

A. Thorburn, D. Thamm, Rebecca A. Barnard, 2014, Autophagy.

Circumventing autophagy inhibition

A. Thorburn, Christina G. Towers, C. Towers, 2019, Cell cycle.

Measuring Autophagy in the Context of Cancer.

A. Thorburn, M. Morgan, 2016, Advances in experimental medicine and biology.

Autophagy as a Therapeutic Target in Cancer

A. Thorburn, J. Samson, 2016 .

Inhibition of Mer and Axl Receptor Tyrosine Kinases in Astrocytoma Cells Leads to Increased Apoptosis and Improved Chemosensitivity

A. Thorburn, A. Donson, N. Foreman, 2010, Molecular Cancer Therapeutics.

Regulation of cell proliferation and migration by p62 through stabilization of Twist1

A. Thorburn, T. He, Seungmin Hwang, 2014, Proceedings of the National Academy of Sciences.

Identifying specific receptors for cargo-mediated autophagy

A. Thorburn, Megan L. Goodall, 2014, Cell Research.

Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells

H. Ford, A. Thorburn, J. Thorburn, 2017, Molecular Pharmacology.

A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.

M. Willingham, A. Thorburn, A. Frankel, 2003, Cancer research.

Efficient expression of miniprep plasmid DNA after needle micro-injection into somatic cells.

A. Thorburn, A. Alberts, 1993, BioTechniques.

Regulation of HMGB1 release by autophagy

A. Thorburn, J. Thorburn, A. Frankel, 2009, Autophagy.

Surgical procedures suppress autophagic flux in the kidney

Daniel J. Atwood, J. Klawitter, A. Thorburn, 2021, Cell Death & Disease.

Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients

A. Thorburn, Jean M. Mulcahy Levy, 2019, Cell Death & Differentiation.

Targeting autophagy in cancer

A. Thorburn, Christina G. Towers, J. Levy, 2017, Nature Reviews Cancer.

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.

A. Thorburn, D. Mirsky, V. Amani, 2014, Cancer discovery.

I think autophagy controls the death of my cells: What do I do to get my paper published?

A. Thorburn, 2011, Autophagy.

RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis

A. Thorburn, Jihye Kim, A. Tan, 2015, EMBO reports.

The C-terminal Tails of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas Receptors Have Opposing Functions in Fas-associated Death Domain (FADD) Recruitment and Can Regulate Agonist-specific Mechanisms of Receptor Activation*

A. Thorburn, John Calvin Reed, Ronald L. Johnson, 2004, Journal of Biological Chemistry.

Rapid transcriptional assay for the expression of two distinct reporter genes by microinjection.

J. Frost, A. Thorburn, A. Alberts, 1993, DNA and cell biology.

Title: Autophagy Inhibition Improves Chemosensitivity in BRAF Brain Tumors

A. Thorburn, D. Mirsky, A. Donson, 2014 .

Translational evidence that impaired autophagy contributes to arterial ageing

A. Thorburn, G. Pierce, D. Seals, 2012, The Journal of physiology.

Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.

A. Thorburn, M. S. Miller, A. Frankel, 2004, Experimental hematology.

The effect of trehalose on autophagy-related proteins and cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease.

Daniel J. Atwood, A. Thorburn, K. Hopp, 2020, Cellular signalling.

Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases.

S. Shenolikar, A. Thorburn, M. Mumby, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Autophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?

A. Thorburn, D. Gewirtz, Molly L Bristol, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

A. Thorburn, D. Gustafson, Christina G. Towers, 2019, SSRN Electronic Journal.

Autophagy and disease

A. Thorburn, 2017, The Journal of Biological Chemistry.

Regulation of Apoptosis by Autophagy to Enhance Cancer Therapy

A. Thorburn, Kenneth D. Tompkins, 2019, The Yale journal of biology and medicine.

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

H. Ford, A. Thorburn, R. Camidge, 2013, Oncogene.

Expression in Xenopus oocytes.

A. Chambers, M. Braddock, A. Kingsman, 1990, Current opinion in biotechnology.

Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent

A. Thorburn, J. Thorburn, C. Cummings, 2014, Autophagy.

The vitamin E analogue α-TEA stimulates tumor autophagy and enhances antigen cross-presentation.

A. Thorburn, J. Thorburn, T. Hahn, 2012, Cancer research.

Microenvironment and Immunology The Vitamin E Analog aTEA Stimulates Tumor Autophagy and Enhances Antigen Cross-Presentation

A. Thorburn, J. Thorburn, T. Hahn, 2012 .

Diphtheria toxin-epidermal growth factor fusion protein and Pseudomonas exotoxin-interleukin 13 fusion protein exert synergistic toxicity against human glioblastoma multiforme cells.

M. Willingham, A. Thorburn, S. Tatter, 2003, Bioconjugate chemistry.

MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb protein.

A. Thorburn, J. Feramisco, P. Walton, 1993, Molecular biology of the cell.

The Tyrosine Kinase Inhibitor, Genistein, Prevents α-Adrenergic-Induced Cardiac Muscle Cell Hypertrophy by Inhibiting Activation of the Ras-MAP Kinase Signaling Pathway

A. Thorburn, J. Thorburn, 1994 .

Cell density and contraction regulate p 38 MAP kinase-dependent responses in neonatal rat cardiac myocytes

A. Thorburn, J. Thorburn, W. A. Hines, 1999 .

Cell density and contraction regulate p38 MAP kinasedependent responses in neonatal rat cardiac myocytes.

A. Thorburn, J. Thorburn, W. A. Hines, 1999, American journal of physiology. Heart and circulatory physiology.

A Novel Apoptosis Pathway that is Defective in Early Breast Cancer

A. Thorburn, D. Phil., 2003 .

HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy.

S. Powers, A. Thorburn, K. Chien, 1993, The Journal of biological chemistry.

Apoptotic pathway manipulation.

A. Thorburn, D. Camidge, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Protein Tyrosine Phosphatase‐N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis

A. Thorburn, S. Groshong, L. Ortiz, 2018, American journal of respiratory and critical care medicine.

Ras and rho are required for galphaq-induced hypertrophic gene expression in neonatal rat cardiac myocytes.

A. Thorburn, W. A. Hines, Andrew Thorburn, 1998, Journal of molecular and cellular cardiology.

Increased mTOR and suppressed autophagic flux in the heart of a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease.

Daniel J. Atwood, A. Thorburn, K. Hopp, 2020, Cellular signalling.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Activation of Caspase Pathways during Iron Chelator-mediated Apoptosis*

M. Willingham, M. Brechbiel, A. Thorburn, 2002, The Journal of Biological Chemistry.

Malignant progenitors from patients with CD87+ acute myelogenous leukemia are sensitive to a diphtheria toxin-urokinase fusion protein.

A. Thorburn, A. Frankel, D. Vallera, 2002, Experimental hematology.

Regulation of FADD death domain interactions by the death effector domain identified by a modified reverse two-hybrid screen

D. Stillman, A. Thorburn, L. Thomas, 2002 .

The Insulin-like Growth Factor I Receptor/Insulin Receptor Tyrosine Kinase Inhibitor PQIP Exhibits Enhanced Antitumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

A. Thorburn, A. Tan, S. Leong, 2010, Clinical Cancer Research.

Sorting cells for basal and induced autophagic flux by quantitative ratiometric flow cytometry

A. Thorburn, J. Gump, Jacob M. Gump, 2014, Autophagy.

The interplay of autophagy and non-apoptotic cell death pathways.

A. Thorburn, S. Cramer, Dannah R. Miller, 2020, International review of cell and molecular biology.

Title : Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

M. Lucia, A. Jimeno, A. Thorburn, 2013 .

A Low-Affinity Serum Response Element Allows Other Transcription Factors To Activate Inducible Gene Expression in Cardiac Myocytes

A. Thorburn, J. Thorburn, W. A. Hines, 1999, Molecular and Cellular Biology.

Retinoic acid–induced expression of autotaxin in N‐myc–amplified neuroblastoma cells

A. Thorburn, J. Dufner-Beattie, R. Lemons, 2001, Molecular carcinogenesis.

Ras activity is required for phenylephrine-induced activation of mitogen-activated protein kinase in cardiac muscle cells.

A. Thorburn, 1994, Biochemical and biophysical research communications.

Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy.

A. Thorburn, J. Thorburn, M. C. Caino, 2021, Developmental cell.

Autophagy and apoptosis: what is the connection?

A. Thorburn, J. Gump, A. Thorburn, 2011, Trends in cell biology.

Autophagy RIPs into cell death

A. Thorburn, S. Cramer, Megan L. Goodall, 2016, Cell cycle.

Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms

A. Thorburn, C. Towers, Darya Wodetzki, 2020, Autophagy.

An apoptosis signaling pathway induced by the death domain of FADD selectively kills normal but not cancerous prostate epithelial cells

A. Thorburn, A. Brothman, J. Thorburn, 2001, Cell Death and Differentiation.

Membrane‐targeting sequences on AKAP79 bind phosphatidylinositol‐4,5‐bisphosphate

A. Thorburn, John D. Scott, M. Dell'Acqua, 1998, The EMBO journal.

Apoptosis and anthracycline cardiotoxicity

A. Thorburn, A. Frankel, 2006, Molecular Cancer Therapeutics.

Recent insights into cell death and autophagy

A. Thorburn, Brent E. Fitzwalter, Brent E. Fitzwalter, 2015, The FEBS journal.

The Insulin-like Growth Factor I Receptor/Insulin Receptor Tyrosine Kinase Inhibitor PQIP Exhibits Enhanced Antitumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

A. Thorburn, A. Tan, S. Leong, 2010, Clinical Cancer Research.

Targeting Autophagy in BRAF-Mutant Tumors.

A. Thorburn, M. Morgan, 2015, Cancer discovery.

IN THE SPOTLIGHT Targeting Autophagy in BRAF -Mutant Tumors

A. Thorburn, M. Morgan, 2015 .

A new mechanism for autophagy regulation of anti-tumor immune responses

A. Thorburn, 2020, Autophagy.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway signaling.

A. Thorburn, 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Autophagy in malignant transformation and cancer progression

Seamus J. Martin, D. Rubinsztein, V. Karantza, 2015, The EMBO journal.

Autophagy and Cancer Therapy

A. Thorburn, D. Thamm, D. Gustafson, 2014, Molecular Pharmacology.

Excitotoxic glutamate insults block autophagic flux in hippocampal neurons

A. Thorburn, S. Coultrap, K. Bayer, 2014, Brain Research.

Autophagy and cancer: Modulation of cell death pathways and cancer cell adaptations

A. Thorburn, C. Towers, Darya Wodetzki, 2019, The Journal of cell biology.

Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy

A. Jimeno, A. Thorburn, B. O'Sullivan, 2011, Nature Medicine.

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis.

D. Green, A. Thorburn, S. Cramer, 2016, Developmental cell.

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

A. Thorburn, K. Davies, D. Aisner, 2017, eLife.

Metastatic cells are preferentially vulnerable to lysosomal inhibition

Rani K. Powers, J. Costello, A. Thorburn, 2018, Proceedings of the National Academy of Sciences.

Targeting autophagy in breast cancer.

A. Thorburn, P. Maycotte, 2014, World journal of clinical oncology.

Autophagy and cancer therapy

A. Thorburn, P. Maycotte, 2011, Cancer biology & therapy.

Therapeutic Targeting of Autophagy☆

A. Thorburn, C. Towers, 2016, EBioMedicine.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

A. Thorburn, P. Timpson, K. Anderson, 2012, Cell cycle.

Autophagy in cancer: good, bad, or both?

A. Thorburn, Andrew Thorburn, Melanie M Hippert, 2006, Cancer research.

Autophagy and organelle homeostasis in cancer.

A. Thorburn, Dannah R. Miller, 2021, Developmental cell.

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

A. Thorburn, H. Horita, J. Redzic, 2008, Cell Death and Differentiation.

Studying autophagy’s relationship to cell death

A. Thorburn, 2008, Autophagy.

Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion

Kenneth L. Jones, A. Thorburn, J. Thorburn, 2015, Molecular Cancer Research.

Autophagy variation within a cell population determines cell fate via selective degradation of Fap-1

A. Thorburn, D. Riches, M. Morgan, 2013, Nature Cell Biology.

Fatty acid synthase: a novel target for antiglioma therapy

S. Kridel, A. Thorburn, S. Hebbar, 2006, British Journal of Cancer.

Targeting autophagy during cancer therapy to improve clinical outcomes.

A. Thorburn, J. Levy, 2011, Pharmacology & therapeutics.

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

S. Finkbeiner, D. Rubinsztein, D. Klionsky, 2011, Autophagy.

N Terminus Is Essential for Tropomyosin Functions

A. Thorburn, S. Hitchcock-DeGregori, S. Bharadwaj, 2004, Journal of Biological Chemistry.

Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.

H. Ford, A. Thorburn, K. Behbakht, 2007, Cancer research.

Death receptor-induced cell killing.

A. Thorburn, Andrew Thorburn, 2004, Cellular signalling.

FOXO3 links autophagy to apoptosis

A. Thorburn, Brent E. Fitzwalter, 2018, Autophagy.

Autophagy and cell death.

A. Thorburn, T. Yonekawa, 2013, Essays in biochemistry.

Consensus guidelines for the detection of immunogenic cell death

P. Vandenabeele, S. Loi, L. Zitvogel, 2014, Oncoimmunology.

Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

A. Thorburn, G. Marcucci, K. Choi, 2015, Cell Research.

A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance

H. Ford, A. Thorburn, Jihye Kim, 2017, Molecular Cancer Research.

Apoptosis induced by overexpression of hMSH2 or hMLH1.

A. Thorburn, M. Meuth, R. Fishel, 1999, Cancer research.

Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels.

D. Green, A. Thorburn, A. Oberst, 2014, Cell reports.

TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them.

H. Ford, A. Thorburn, K. Behbakht, 2008, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Acute Myeloid Leukemia-Targeted Toxin Activates Both Apoptotic and Necroptotic Death Mechanisms

A. Thorburn, H. Horita, A. Frankel, 2008, PloS one.

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

A. Thorburn, J. Thorburn, C. Cummings, 2012, Autophagy.

Targeting Chaperone-Mediated Autophagy in Cancer

A. Thorburn, J. Debnath, 2011, Science Translational Medicine.

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer.

M. Lucia, A. Jimeno, A. Thorburn, 2013, Cancer research.

Specificity and prognostic validation of a polyclonal antibody to detect Six1 homeoprotein in ovarian cancer.

H. Ford, A. Thorburn, M. Spillman, 2012, Gynecologic oncology.

Diphtheria Toxin–Epidermal Growth Factor Fusion Protein DAB389EGF for the Treatment of Bladder Cancer

A. Thorburn, M. Varella‐Garcia, Xiaoping Yang, 2012, Clinical Cancer Research.

Cancer Therapy : Preclinical Diphtheria Toxin – Epidermal Growth Factor Fusion Protein DAB 389 EGF for the Treatment of Bladder Cancer

A. Thorburn, M. Varella‐Garcia, Xiaoping Yang, 2012 .

Crosstalk between autophagy and apoptosis: Mechanisms and therapeutic implications.

A. Thorburn, 2020, Progress in molecular biology and translational science.

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition.

A. Thorburn, A. Goodspeed, D. Gustafson, 2019, Developmental cell.

Targeting the Lysosome for Cancer Therapy.

A. Thorburn, C. Towers, 2017, Cancer discovery.

Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers.

A. Thorburn, B. Bay, D. Virshup, 2015, The Journal of clinical investigation.

STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious.

A. Thorburn, S. Fosmire, Rebecca A. Barnard, 2014, Cancer research.

Therapeutics , Targets , and Chemical Biology STAT 3-Mediated Autophagy Dependence Identi fi es Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Ef fi cacious

A. Thorburn, S. Fosmire, Rebecca A. Barnard, 2014 .

Inhibiting autophagy by shRNA knockdown

A. Thorburn, J. Thorburn, M. Morgan, 2013, Autophagy.

APOPTOSIS INDUCTION BY TUMOR- TARGETED TOXINS

A. Thorburn, 2005 .

Induction of apoptosis by tumor cell-targeted toxins

A. Thorburn, J. Thorburn, A. Frankel, 2004, Apoptosis.

Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.

A. Thorburn, J. Thorburn, A. Frankel, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

pRS yeast vectors with a LYS2 marker.

D. Stillman, A. Thorburn, P. Eriksson, 2004, BioTechniques.

Activation of Ras by phorbol esters in cardiac myocytes

A. Thorburn, C. Montessuit, C Montessuit, 1999, FEBS letters.

Transcriptional Activation of the Glucose Transporter GLUT1 in Ventricular Cardiac Myocytes by Hypertrophic Agonists*

A. Thorburn, C. Montessuit, 1999, The Journal of Biological Chemistry.

Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy

J. Frost, A. Thorburn, J. Thorburn, 1994, The Journal of cell biology.

clinical and Clinical Estimates of the Basal Apoptotic Rate Cancer Predict the Amount of Apoptosis Induced R ubsequent Proapoptotic Stimuli

A. Thorburn, B. Kavanagh, D. Camidge, 2010 .

Intron-less RNA injected into the nucleus of Xenopus oocytes accesses a regulated translation control pathway.

M. Muckenthaler, M. Braddock, A. Kingsman, 1994, Nucleic acids research.

Distinct TRAIL resistance mechanisms can be overcome by proteasome inhibition but not generally by synergizing agents.

H. Ford, A. Thorburn, K. Behbakht, 2011, Cancer research.

EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins

A. Thorburn, H. Horita, J. Thorburn, 2009, Journal of Neuro-Oncology.

Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.

M. Peter, A. Thorburn, C. Slaughter, 2005, Molecular cell.

Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells.

A. Thorburn, S. Cramer, J. Thorburn, 2005, Molecular biology of the cell.

BCL-2 Family Inhibitors Enhance Histone Deacetylase Inhibitor and Sorafenib Lethality via Autophagy and Overcome Blockade of the Extrinsic Pathway to Facilitate Killing

A. Thorburn, D. Häussinger, P. Dent, 2009, Molecular Pharmacology.

Mediation of the DCC Apoptotic Signal by DIP13α*

Russell L Finley, R. Finley, A. Thorburn, 2002, The Journal of Biological Chemistry.

Caspase- and serine protease-dependent apoptosis by the death domain of FADD in normal epithelial cells.

A. Thorburn, J. Thorburn, Andrew Thorburn, 2003, Molecular biology of the cell.

Promoter control of translation in Xenopus oocytes.

M. Muckenthaler, M. Braddock, A. Kingsman, 1995, Nucleic acids research.

Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase.

N. Ahn, A. Thorburn, K. Chien, 1995, Molecular biology of the cell.

ZZ-dependent regulation of p62/SQSTM1 in autophagy

A. Thorburn, Y. Kwon, J. Moscat, 2018, Nature Communications.

A Raf‐induced, MEK‐independent signaling pathway regulates atrial natriuretic factor gene expression in cardiac muscle cells

A. Thorburn, C. Jette, Cicely A. Jette, 2000, FEBS letters.

Interleukin-1α mediates the antiproliferative effects of 1,25-dihydroxyvitamin D3 in prostate progenitor/stem cells.

J. Hipp, A. Thorburn, S. Cramer, 2011, Cancer research.

Regulation of Fas-associated Death Domain Interactions by the Death Effector Domain Identified by a Modified Reverse Two-hybrid Screen*

D. Stillman, A. Thorburn, L. Thomas, 2002, Journal of Biological Chemistry.

MAP kinase‐ and Rho‐dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells

A. Thorburn, J. Thorburn, Shuichan Xu, 1997, EMBO Journal.

Using BRAFV600E as a marker of autophagy dependence in pediatric brain tumors

A. Thorburn, N. Foreman, J. Levy, 2014, Autophagy.

Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease

A. Thorburn, Rebecca A. Barnard, R. Hansen, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Co-Operation Between FADD and Bin1 in Prostate Cancer Apoptosis

A. Thorburn, 2005 .

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.

A. Thorburn, J. Espinosa, Z. Andrysik, 2018, Developmental cell.

Autophagy and Its Effects: Making Sense of Double-Edged Swords

A. Thorburn, 2014, PLoS biology.

Mechanistic insight into the regulation of SQSTM1/p62

A. Thorburn, Y. Kwon, J. Linares, 2019, Autophagy.

MyoDInduced CellCycle Arrest IsAssociated with Increased Nuclear Affinity oftheRbProtein

A. Thorburn, 1993 .

Measurement of caspase activity in individual cells reveals differences in the kinetics of caspase activation between cells

A. Thorburn, M. Morgan, 2001, Cell Death and Differentiation.

A nuclear translational block imposed by the HIV-1 U3 region is relieved by the Tat-TAR interaction

A. Chambers, M. Braddock, A. Kingsman, 1990, Cell.

Modulation of pediatric brain tumor autophagy and chemosensitivity

A. Thorburn, J. Levy, 2011, Journal of Neuro-Oncology.

A caspase-independent way to kill cancer cells

A. Thorburn, Brent E. Fitzwalter, 2017, Nature Cell Biology.

Direct Binding of Fas-associated Death Domain (FADD) to the Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor DR5 Is Regulated by the Death Effector Domain of FADD*

A. Thorburn, John Calvin Reed, F. Salsbury, 2004, Journal of Biological Chemistry.

Preclinical and Clinical Estimates of the Basal Apoptotic Rate of a Cancer Predict the Amount of Apoptosis Induced by Subsequent Proapoptotic Stimuli

A. Thorburn, B. Kavanagh, D. Camidge, 2010, Clinical Cancer Research.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.

M. Willingham, A. Thorburn, A. Frankel, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Enhancing anti-tumor immunity by autophagy inhibition

A. Thorburn, C. Towers, 2021, Nature Cancer.

Acute myeloid leukemia-targeted toxins kill tumor cells by cell type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death

A. Thorburn, H. Horita, A. Frankel, 2008, Leukemia.

Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms

A. Thorburn, Jihye Kim, S. Eckhardt, 2018, Molecular Cancer Therapeutics.

Dexamethasone inhibits insulin-like growth factor signaling and potentiates myoblast apoptosis.

A. Thorburn, J. Singleton, B. Baker, 2000, Endocrinology.

Cell Death and Survival Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL 6 Secretion

Kenneth L. Jones, A. Thorburn, J. Thorburn, 2015 .

Blocking of Tat-dependent HIV-1 RNA modification by an inhibitor of RNA polymerase II processivity

M. Braddock, A. Kingsman, S. Kingsman, 1991, Nature.